Proton Pump

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研究领域

抑制剂选择性比较

Proton Pump产品

所有产品 Proton Pump抑制剂(16)

目录号	产品描述	文献引用	实验数据
S1354	Lansoprazole Lansoprazole (A-65006, AG-1749)是一种质子泵抑制剂（PPI），防止胃产生胃酸。	Front Microbiol, 2019, 10:2790
S1389	Omeprazole Omeprazole 是一种质子泵抑制剂，用于治疗消化不良，消化性溃疡，胃食管逆流，咽喉逆流。	Redox Biol, 2020, 32:101464 Int J Oncol, 2019, 54(3):1061-1070
S1413	Bafilomycin A1(Baf-A1) Bafilomycin A1(Baf-A1)是一种液泡H⁺-ATPase抑制剂，IC50为0.44 nM。研究发现 Bafilomycin A1 可以抑制自噬，但是诱导凋亡。	Sci Adv, 2020, 29;6(18):eaax7881 Autophagy, 2020, 10.1080/15548627.2020.1740529 Autophagy, 2020, 16(6):1061-1076	Mitochondrial depolarization mediated relocation of mitochondrial RC-TPP into lysosomes and the ensuing lysosomal acidity triggered rhodamine fluorescence. RC-TPP-loaded Tom20-GFP+ HeLa cells were treated without or with CCCP (20 μM) in the presence or absence of BFA (200 nM). Colocalization of Tom20-GFP (in green) and mitochondrial RC-TPP (in blue) is shown in cyan. Scale bar: 10 μm.
S1743	NEXIUM (esomeprazole magnesium) Esomeprazole Magnesium是一种质子泵抑制剂，减少胃酸分泌。
S4075	Zinc Pyrithione Zinc Pyrithione是一种抗真菌和抗细菌药物，可以通过阻断质子泵破坏膜转运。	Biol Reprod, 2019, 100(2):468-478 Cell Syst, 2017, 4(6-:600-610
S2222	PF-3716556 PF-3716556是一种有效的，选择性的P-CAB钾离子竞争性酸抑制剂，在离子渗透和离子密集检测中，抑制猪H⁺，K⁺-ATPase活性，抑制胃酸分泌，对Na⁺，K⁺-ATPas没有作用活性，用于治疗胃食管返流疾病。
S4099	Dexlansoprazole Dexlansoprazole是Lansoprazole的右旋对映体，是质子泵抑制剂（PPI），具有双重缓释性能。	Front Microbiol, 2019, 10:2790
S4845	Rabeprazole Rabeprazole is an oral inhibitor of proton pump and blocks the production of acid by the stomach.	Front Microbiol, 2019, 10:2790
S5658	Omeprazole Sodium Omeprazole Sodium is the sodium salt form of omeprazole, which is a proton pump inhibitor and suppresses gastric acid secretion.
S5502	Ilaprazole sodium Ilaprazole sodium is the sodium salt form of ilaprazole, which is a proton pump inhibitor.
S3666	Ilaprazole Ilaprazole是新型的质子泵 (proton pump)抑制剂，用于治疗消化不良、消化性溃疡、胃食管返流疾病和十二指肠溃疡。它能抑制H+/K+-ATPase，IC50为6 μM。
S4212	Tenatoprazole Tenatoprazole 是proton pump 抑制剂类前药, 抑制质子的运输，IC50为3.2 μM。
S4665	Rabeprazole sodium Rabeprazole是一种抗溃疡药物，是质子泵的抑制剂。
S4538	Pantoprazole sodium Pantoprazole (SKF96022, BY-1023) 是质子泵抑制剂，抑制胃酸分泌。它作用于胃黏膜壁细胞，可逆性抑制(H+/K+)-ATPase功能以及抑制胃酸的产生。
S2105	Pantoprazole Pantoprazole是一种不可逆地、特异性地结合质子泵的抑制剂。	Front Microbiol, 2019, 10:2790
S5058	Revaprazan Hydrochloride Revaprazan Hydrochloride (YH1885)是一种新型可逆的proton pump抑制剂，具有长效抑酸活性。

目录号	产品描述	文献引用	实验数据
S1354	Lansoprazole Lansoprazole (A-65006, AG-1749)是一种质子泵抑制剂（PPI），防止胃产生胃酸。	Front Microbiol,2019, 10:2790
S1389	Omeprazole Omeprazole 是一种质子泵抑制剂，用于治疗消化不良，消化性溃疡，胃食管逆流，咽喉逆流。	Redox Biol,2020, 32:101464 Int J Oncol,2019, 54(3):1061-1070
S1413	Bafilomycin A1(Baf-A1) Bafilomycin A1(Baf-A1)是一种液泡H⁺-ATPase抑制剂，IC50为0.44 nM。研究发现 Bafilomycin A1 可以抑制自噬，但是诱导凋亡。	Sci Adv,2020, 29;6(18):eaax7881 Autophagy,2020, 10.1080/15548627.2020.1740529 Autophagy,2020, 16(6):1061-1076	Mitochondrial depolarization mediated relocation of mitochondrial RC-TPP into lysosomes and the ensuing lysosomal acidity triggered rhodamine fluorescence. RC-TPP-loaded Tom20-GFP+ HeLa cells were treated without or with CCCP (20 μM) in the presence or absence of BFA (200 nM). Colocalization of Tom20-GFP (in green) and mitochondrial RC-TPP (in blue) is shown in cyan. Scale bar: 10 μm.
S1743	NEXIUM (esomeprazole magnesium) Esomeprazole Magnesium是一种质子泵抑制剂，减少胃酸分泌。
S4075	Zinc Pyrithione Zinc Pyrithione是一种抗真菌和抗细菌药物，可以通过阻断质子泵破坏膜转运。	Biol Reprod,2019, 100(2):468-478 Cell Syst,2017, 4(6-:600-610
S2222	PF-3716556 PF-3716556是一种有效的，选择性的P-CAB钾离子竞争性酸抑制剂，在离子渗透和离子密集检测中，抑制猪H⁺，K⁺-ATPase活性，抑制胃酸分泌，对Na⁺，K⁺-ATPas没有作用活性，用于治疗胃食管返流疾病。
S4099	Dexlansoprazole Dexlansoprazole是Lansoprazole的右旋对映体，是质子泵抑制剂（PPI），具有双重缓释性能。	Front Microbiol,2019, 10:2790
S4845	Rabeprazole Rabeprazole is an oral inhibitor of proton pump and blocks the production of acid by the stomach.	Front Microbiol,2019, 10:2790
S5658	Omeprazole Sodium Omeprazole Sodium is the sodium salt form of omeprazole, which is a proton pump inhibitor and suppresses gastric acid secretion.
S5502	Ilaprazole sodium Ilaprazole sodium is the sodium salt form of ilaprazole, which is a proton pump inhibitor.
S3666	Ilaprazole Ilaprazole是新型的质子泵 (proton pump)抑制剂，用于治疗消化不良、消化性溃疡、胃食管返流疾病和十二指肠溃疡。它能抑制H+/K+-ATPase，IC50为6 μM。
S4212	Tenatoprazole Tenatoprazole 是proton pump 抑制剂类前药, 抑制质子的运输，IC50为3.2 μM。
S4665	Rabeprazole sodium Rabeprazole是一种抗溃疡药物，是质子泵的抑制剂。
S4538	Pantoprazole sodium Pantoprazole (SKF96022, BY-1023) 是质子泵抑制剂，抑制胃酸分泌。它作用于胃黏膜壁细胞，可逆性抑制(H+/K+)-ATPase功能以及抑制胃酸的产生。
S2105	Pantoprazole Pantoprazole是一种不可逆地、特异性地结合质子泵的抑制剂。	Front Microbiol,2019, 10:2790
S5058	Revaprazan Hydrochloride Revaprazan Hydrochloride (YH1885)是一种新型可逆的proton pump抑制剂，具有长效抑酸活性。

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