Proton Pump

信号通路图

研究领域

  • 抑制剂选择性比较
  • 溶解性比较
目录号 产品目录 溶解度(25°C)
水 DMSO 酒精
S1354 Lansoprazole <1 mg/mL 74 mg/mL 14 mg/mL
S1389 Omeprazole <1 mg/mL 69 mg/mL 13 mg/mL
S1413 Bafilomycin A1(Baf-A1) <1 mg/mL 6 mg/mL <1 mg/mL
S1743 NEXIUM (esomeprazole magnesium) <1 mg/mL 143 mg/mL 143 mg/mL
S4075 Zinc Pyrithione <1 mg/mL 30 mg/mL <1 mg/mL
S5658 Omeprazole Sodium 73 mg/mL 73 mg/mL 73 mg/mL
S5502 Ilaprazole sodium -1 mg/mL 78 mg/mL -1 mg/mL
S4845 Rabeprazole 71 mg/mL 71 mg/mL 71 mg/mL
S5058 Revaprazan Hydrochloride -1 mg/mL 16 mg/mL -1 mg/mL
S2222 PF-3716556 <1 mg/mL 79 mg/mL 79 mg/mL
S4099 Dexlansoprazole <1 mg/mL 74 mg/mL <1 mg/mL
S3666 Ilaprazole <1 mg/mL 73 mg/mL 14 mg/mL
S4212 Tenatoprazole <1 mg/mL 46 mg/mL 14 mg/mL
S4665 Rebeprazole sodium 76 mg/mL 76 mg/mL 76 mg/mL
S4538 Pantoprazole sodium 81 mg/mL 81 mg/mL 81 mg/mL
S2105 Pantoprazole <1 mg/mL 76 mg/mL 76 mg/mL
产品目录 产品描述 文献引用 实验数据
S1354

Lansoprazole

Lansoprazole是一种质子泵抑制剂（PPI），防止胃产生胃酸。

S1389

Omeprazole

Omeprazole 是一种质子泵抑制剂，用于治疗消化不良，消化性溃疡，胃食管逆流，咽喉逆流。
S1413

Bafilomycin A1(Baf-A1)

Bafilomycin A1(Baf-A1)是一种液泡H+-ATPase抑制剂，IC50为0.44 nM。
Immunity, 2016, 45(4):944
Cancer Lett, 2018, 431:85-95
J Exp Clin Cancer Res, 2018, 37(1):251
S1743

NEXIUM (esomeprazole magnesium)

Esomeprazole Magnesium是一种质子泵抑制剂，减少胃酸分泌。

S4075

Zinc Pyrithione

Zinc Pyrithione是一种抗真菌和抗细菌药物，可以通过阻断质子泵破坏膜转运。
S5658New

Omeprazole Sodium

Omeprazole Sodium is the sodium salt form of omeprazole, which is a proton pump inhibitor and suppresses gastric acid secretion.
S5502New

Ilaprazole sodium

Ilaprazole sodium is the sodium salt form of ilaprazole, which is a proton pump inhibitor.
S4845New

Rabeprazole

Rabeprazole is an oral inhibitor of proton pump and blocks the production of acid by the stomach.
S5058New

Revaprazan Hydrochloride

Revaprazan Hydrochloride是一种新型可逆的proton pump抑制剂，具有长效抑酸活性。
S2222

PF-3716556

PF-3716556是一种有效的，选择性的P-CAB钾离子竞争性酸抑制剂，在离子渗透和离子密集检测中，抑制猪H+，K+-ATPase活性，抑制胃酸分泌，对Na+，K+-ATPas没有作用活性，用于治疗胃食管返流疾病。
S4099

Dexlansoprazole

Dexlansoprazole是Lansoprazole的右旋对映体，是质子泵抑制剂（PPI），具有双重缓释性能。
S3666

Ilaprazole

Ilaprazole是新型的质子泵 (proton pump)抑制剂，用于治疗消化不良、消化性溃疡、胃食管返流疾病和十二指肠溃疡。它能抑制H+/K+-ATPase，IC50为6 μM。
S4212

Tenatoprazole

Tenatoprazole 是proton pump 抑制剂类前药, 抑制质子的运输，IC50为3.2 μM。

S4665

Rebeprazole sodium

Rabeprazole是一种抗溃疡药物，是质子泵的抑制剂。
S4538

Pantoprazole sodium

Pantoprazole是质子泵抑制剂，抑制胃酸分泌。它作用于胃黏膜壁细胞，可逆性抑制(H+/K+)-ATPase功能以及抑制胃酸的产生。
S2105

Pantoprazole

Pantoprazole是一种不可逆地、特异性地结合质子泵的抑制剂。

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