• Cathepsin
  • Calpain
  • Cruzain
  • Papainb
  • Cathepsin

Cathepsin 选择性抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S0194 Balicatib Balicatib (AAE-581) is a potent and selective inhibitor of the osteoclastic enzyme cathepsin K. Selective
S4591 Nitroxoline Nitroxoline (8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol, 5-Nitro-8-hydroxyquinoline) is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. Nitroxoline impairs tumor progression in vitro and in vivo by inhibiting cathepsin B activity. Selective
S7420 CA-074 methyl ester (CA-074 Me) CA-074 methyl ester (CA-074 Me, Cathepsin B Inhibitor IV) is a membrane-permeable derivative of CA-074 and acts as an irreversible cathepsin B inhibitor. Selective
S1115 Odanacatib Odanacatib is a potent, selective, and neutral inhibitor of cathepsin K (human/rabbit) with IC50 of 0.2 nM/1 nM, and demonstrated high selectivity versus off-target cathepsin B, L, S. Phase 3. Selective Cathepsin K (human), IC50: 0.2 nM; Cathepsin K (rabbit), IC50: 1 nM
S5611 2-cyano-Pyrimidine 2-cyano-Pyrimidine is a cathepsin K inhibitor with an IC50 of 170 nM. Selective Cathepsin K, IC50: 170 nM
S7381 Pepstatin A Pepstatin A (Pepstatin) is a potent aspartic protease inhibitor, and also inhibits HIV replication. Pepstatin A is also an inhibitor of cathepsins D and cathepsins E. Pepstatin A inhibits autophagy by suppressing lysosomal proteases. Selective
S2847 Cathepsin Inhibitor 1 Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively. Pan Cathepsin L, pIC50: 7.9; Cathepsin L2, pIC50: 6.7; Cathepsin S, pIC50: 6; Cathepsin K, pIC50: 5.5; Cathepsin B, pIC50: 5.2
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