HT1080 |
Growth Inhibition Assay |
1-100 μM |
4/24/48 h |
induces cell death significantly in a very low concentration |
25078064 |
MCF7 BMI1 |
Function Assay |
10-100 μM |
2 h |
ETOP induces ATM activation |
25088203 |
MCF7 EV |
Function Assay |
10-100 μM |
2 h |
ETOP induces ATM activation |
25088203 |
MCF 7BMI1 |
Function Assay |
10-100 μM |
2 h |
induces production of γH2AX |
25088203 |
MCF7 EV |
Function Assay |
10-100 μM |
2 h |
induces production of γH2AX |
25088203 |
MKL-1 |
Function Assay |
10-1000 nM |
4 d |
induces the induction of MHC-I expression |
25116754 |
NSCs |
Growth Inhibition Assay |
0.01-300 μM |
48 h |
IC50=0.3-3 μM |
25119185 |
UW228-3 |
Growth Inhibition Assay |
0.01-300 μM |
48 h |
IC50=0.99 μM |
25119185 |
DU145 stem-like |
Function Assay |
10-100 μM |
2 h |
increases the pCHK1 expression and decreases the pCHK1 expression in a dose-dependent manner |
25149681 |
DU145 |
Function Assay |
10-100 μM |
2 h |
increases the pCHK1 expression and decreases the pCHK1 expression in a dose-dependent manner |
25149681 |
DU145 stem-like |
Apoptosis Assay |
10-100 μM |
8 h |
induces cell death in a dose-dependent manner |
25149681 |
DU145 |
Apoptosis Assay |
10-100 μM |
8 h |
induces cell death significantly in a very low concentration |
25149681 |
SH-EP |
Function Assay |
20 μg/ml |
24 h |
increases the expression of endogenous DEPP |
25261981 |
MCF7 |
Growth Inhibition Assay |
5-100 μM |
7 d |
inhibits cell growth in a dose-dependent manner |
25472619 |
SMMC-7721 |
Function Assay |
40 μM |
48 h |
induces γH2AX foci formation |
25544361 |
Hep3B |
Function Assay |
0.1-10 μM |
24 h |
suppresses the expression of hepcidin mRNA |
25633564 |
Hep3B |
Function Assay |
10 μM |
48 h |
reduces the enhancing effect of BMP-6 |
25633564 |
HEK293T |
Growth Inhibition Assay |
1-5 μM |
48 h |
IC50=2.42 ± 0.05 μM |
25746763 |
SW480 |
Growth Inhibition Assay |
0.5-2.5 μM |
48 h |
IC50=4.92 ± 0.33 μM |
25746763 |
COLO 205 |
Growth Inhibition Assay |
0.5-2.5 μM |
48 h |
IC50=1.61 ± 0.02 μM |
25746763 |
Caco2 |
Growth Inhibition Assay |
0.5-2.5 μM |
48 h |
IC50=7.26 ± 1.68 μM |
25746763 |
HT-29 |
Growth Inhibition Assay |
0.5-2.5 μM |
48 h |
IC50=7.2 ± 1.04 μM |
25746763 |
HCT116 |
Growth Inhibition Assay |
0.5-2.5 μM |
48 h |
IC50=1.73 ± 0.21 μM |
25746763 |
U87 |
Growth Inhibition Assay |
0-50 μM |
48 h |
decreases cell viability which can be enhanced by silibinin |
25750273 |
HT1080 |
Function Assay |
0.0001-100 μM |
1-24 h |
induces p-p53(ser15) in both time- and concentration-dependent manner |
25078064 |
HT1080 |
Growth Inhibition Assay |
0.0001-100 μM |
24 h |
causes an increase in the number of cells in G2/M, while decreasing S and G1 phase cells |
25078064 |
Kelly |
Growth Inhibition Assay |
0-10 μM |
72 h |
IC50=1.518 μM |
25008900 |
SH-SY5Y |
Growth Inhibition Assay |
0-10 μM |
72 h |
IC50=0.754 μM |
25008900 |
SK-N-AS |
Growth Inhibition Assay |
0-10 μM |
72 h |
IC50=1.712 μM |
25008900 |
SK-N-DZ |
Growth Inhibition Assay |
0-10 μM |
72 h |
IC50=5.485 μM |
25008900 |
MDA-MB-231 |
Growth Inhibition Assay |
|
48 h |
IC50=12.8 ± 1.0 μM |
25216378 |
T-47D |
Growth Inhibition Assay |
|
48 h |
IC50=7.7 ± 0.7 μM |
25216378 |
MCF-7 |
Growth Inhibition Assay |
|
48 h |
IC50=7.2 ± 0.8 μM |
25216378 |
FaDu |
Growth Inhibition Assay |
|
72 h |
IC50=5.02 ± 1.15 μM |
25220729 |
CAL27 |
Growth Inhibition Assay |
|
72 h |
IC50=4.27 ± 1.14 μM |
25220729 |
SCC25 |
Growth Inhibition Assay |
|
72 h |
IC50=8.41 ± 1.11 μM |
25220729 |
FaDu |
Growth Inhibition Assay |
|
48 h |
IC50=6.43 ± 1.13 μM |
25220729 |
CAL27 |
Growth Inhibition Assay |
|
48 h |
IC50=18.24 ± 1.15 μM |
25220729 |
SCC25 |
Growth Inhibition Assay |
|
48 h |
IC50=20.86 ± 1.07 μM |
25220729 |
FaDu |
Growth Inhibition Assay |
|
24 h |
IC50=25.89 ± 1.13 μM |
25220729 |
CAL27 |
Growth Inhibition Assay |
|
24 h |
IC50=52.1 ± 1.09 μM |
25220729 |
SCC25 |
Growth Inhibition Assay |
|
24 h |
IC50=43.3 ± 1.12 μM |
25220729 |
K/VP.5 |
Growth Inhibition Assay |
|
72 h |
IC50=4.9 μM |
25282653 |
K562 |
Growth Inhibition Assay |
|
72 h |
IC50=0.29 μM |
25282653 |
HeLa |
Growth Inhibition Assay |
|
72 h |
IC50=3.9 ± 2.3 μM |
25486219 |
Jurkat |
Growth Inhibition Assay |
|
72 h |
IC50=1.2 ± 1.5 μM |
25486219 |
MCF-7 |
Growth Inhibition Assay |
|
72 h |
IC50=10.9 ± 2.1 μM |
25486219 |
MDA-MB-231 |
Growth Inhibition Assay |
|
72 h |
IC50=21.2 ± 4.2 μM |
25486219 |
HD-MY-Z |
Growth Inhibition Assay |
|
24/48/72 h |
IC50>100 μM |
25048236 |
DOHH-2 |
Growth Inhibition Assay |
|
24 h |
IC50>100 μM |
25048236 |
DOHH-2 |
Growth Inhibition Assay |
|
48 h |
IC50=19.9 μM |
25048236 |
DOHH-2 |
Growth Inhibition Assay |
|
72 h |
IC50=5 μM |
25048236 |
REH |
Growth Inhibition Assay |
|
24 h |
IC50=0.027 μM |
25048236 |
REH |
Growth Inhibition Assay |
|
48 h |
IC50=0.014 μM |
25048236 |
REH |
Growth Inhibition Assay |
|
72 h |
IC50=0.015 μM |
25048236 |
HH |
Growth Inhibition Assay |
|
24 h |
IC50=104.7 μM |
25048236 |
HH |
Growth Inhibition Assay |
|
48 h |
IC50=48.6 μM |
25048236 |
HH |
Growth Inhibition Assay |
|
72 h |
IC50=14.7 μM |
25048236 |
HuT-78 |
Growth Inhibition Assay |
|
24 h |
IC50=9.3 μM |
25048236 |
HuT-78 |
Growth Inhibition Assay |
|
48 h |
IC50=4.3 μM |
25048236 |
HuT-78 |
Growth Inhibition Assay |
|
72 h |
IC50=4.2 μM |
25048236 |
OPM-2 |
Growth Inhibition Assay |
|
24 h |
IC50=24.1 μM |
25048236 |
OPM-2 |
Growth Inhibition Assay |
|
48 h |
IC50=4 μM |
25048236 |
OPM-2 |
Growth Inhibition Assay |
|
72 h |
IC50=1.3 μM |
25048236 |
RPMI-8226 |
Growth Inhibition Assay |
|
24 h |
IC50=106.6 μM |
25048236 |
RPMI-8226 |
Growth Inhibition Assay |
|
48 h |
IC50=91.1 μM |
25048236 |
RPMI-8226 |
Growth Inhibition Assay |
|
72 h |
IC50=14.9 μM |
25048236 |
U-266 |
Growth Inhibition Assay |
|
24 h |
IC50=86.2 μM |
25048236 |
U-266 |
Growth Inhibition Assay |
|
48 h |
IC50=68.4 μM |
25048236 |
U-266 |
Growth Inhibition Assay |
|
72 h |
IC50=27.4 μM |
25048236 |
HepG2 |
Growth Inhibition Assay |
|
48 h |
IC50=13.65 ± 0.92 μM |
24996136 |
A549 |
Growth Inhibition Assay |
|
48 h |
IC50=241.9 ± 31.23 μM |
24996136 |
MCF7 |
Growth Inhibition Assay |
|
48 h |
IC50=81.09 ± 14.21 μM |
24996136 |
HL-60 |
Growth Inhibition Assay |
|
72 h |
IC50=0.12 μM |
24993014 |
HL-60[R] |
Growth Inhibition Assay |
|
72 h |
IC50=3.12 μM |
24993014 |
MO59K |
Growth Inhibition Assay |
|
7 d |
IC50=0.17 μM |
24953561 |
MO59J |
Growth Inhibition Assay |
|
7 d |
IC50=0.1 μM |
24953561 |
ME 180 |
Growth Inhibition Assay |
|
48 h |
IC50=8.9 ± 0.3 μM |
24953027 |
MCF-7 |
Growth Inhibition Assay |
|
48 h |
IC50=23.9 ± 0.3 μM |
24953027 |
HeLa |
Growth Inhibition Assay |
|
48 h |
IC50=4.71 ± 1.4 μM |
24953027 |
MDA-MB-453 |
Growth Inhibition Assay |
|
48 h |
IC50=12.5 ± 0.85 μM |
24953027 |
MDA-MB-231 |
Growth Inhibition Assay |
|
48 h |
IC50=24.22 ± 2.94 μM |
24953027 |
PC-3 |
Growth Inhibition Assay |
|
48 h |
IC50=14.4 ± 3.23 μM |
24953027 |
HT-29 |
Growth Inhibition Assay |
|
48 h |
IC50=21.45 ± 3.87 μM |
24953027 |
BGC-823 |
Growth Inhibition Assay |
|
48 h |
IC50=43.74 ± 5.13 μM |
24793877 |
HeLa |
Growth Inhibition Assay |
|
48 h |
IC50=209.90 ± 13.42 μM |
24793877 |
A549 |
Growth Inhibition Assay |
|
48 h |
IC50=139.54 ± 7.05 μM |
24793877 |
HK-2 |
Growth Inhibition Assay |
|
48 h |
IC50=9.17 ± 1.58 μM |
24793877 |
KB |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human KB cells assessed as reduction in cell number after 3 days, ID50 = 0.2 μM. |
1331331 |
KB |
Cytotoxicity assay |
|
3 days |
In vitro cytotoxicity against KB cells after a 3-day incubation., ID50 = 0.2 μM. |
2158562 |
KB |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against KB cells after a 3 day incubation, ID50 = 0.2 μM. |
8120864 |
P388 |
Cytotoxicity assay |
|
1 hr |
In vitro cytotoxicity against P388 murine leukemia cells in culture in a clonogenic assay after 1 hour exposure to drug, IC50 = 0.3 μM. |
8410993 |
Bel7402 |
Cytotoxicity assay |
|
5 days |
Cytotoxicity against human Bel7402 cells after 5 days by MTT assay, IC50 = 1.9 μM. |
8778240 |
BGC |
Cytotoxicity assay |
|
5 days |
Cytotoxicity against human BGC cells after 5 days by MTT assay, IC50 = 6.7 μM. |
8778240 |
HCT8 |
Cytotoxicity assay |
|
5 days |
Cytotoxicity against human HCT8 cells after 5 days by MTT assay, IC50 = 6.4 μM. |
8778240 |
HL60 |
Cytotoxicity assay |
|
5 days |
Cytotoxicity against human HL60 cells after 5 days by MTT assay, IC50 = 0.16 μM. |
8778240 |
C6 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against rat C6 cells after 3 days treated 4 hrs before db-cAMP challenge by MTT assay, LC50 = 0.12 μM. |
8988604 |
HL-60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.025 μM. |
11170674 |
HT-29 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HT-29 cells after 72 hrs by methylene blue assay, IC50 = 2.3 μM. |
14738395 |
KB |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB cells after 72 hrs by methylene blue assay, IC50 = 1.1 μM. |
14738395 |
KB |
Function assay |
|
3 days |
Dose required for reduction in camptothecin resistant human nasopharyngeal KB cancer cells after 3 days incubation, ED50 = 7 μM. |
15456257 |
KB-7d |
Function assay |
|
3 days |
Dose required for reduction in etoposide resistant human nasopharyngeal KB-7d cancer cells after 3 days incubation, ED50 = 17.2 μM. |
15456257 |
A549 |
Function assay |
|
3 days |
Dose required for reduction in human lung A549 cancer cells after 3 days incubation, ED50 = 10.6 μM. |
15456257 |
KB |
Function assay |
|
3 days |
Dose required to cause reduction in human nasopharyngeal KB cancer cells after 3 days incubation, ED50 = 0.3 μM. |
15456257 |
1A9 |
Function assay |
|
3 days |
Dose required to cause reduction in human ovarian 1A9 cancer cells after 3 days incubation, ED50 = 0.15 μM. |
15456257 |
HSC2 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human HSC2 cells assessed as cell viability after 24 hrs, IC50 = 41 μM. |
15620262 |
HL60 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human HL60 cells after 24 hrs by MTT assay, IC50 = 25 μM. |
15974617 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay, IC50 = 0.8775 μM. |
16309315 |
TK10 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human TK10 cells after 48 hrs by SRB assay, IC50 = 9.9525 μM. |
16309315 |
UACC62 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human UACC62 cells after 48 hrs by SRB assay, IC50 = 1.13 μM. |
16309315 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by MTT assay, ED50 = 3.76 μM. |
16441087 |
HeLa |
Antiproliferative assay |
|
69 hrs |
Antiproliferative effect against human HeLa cells after 69 hrs by MTT assay, IC50 = 3.6 μM. |
16499324 |
HL60 |
Antiproliferative assay |
|
69 hrs |
Antiproliferative effect against human HL60 cells after 69 hrs, IC50 = 0.21 μM. |
16499324 |
MCF7 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative effect against human MCF7 cells after 72 hrs by MTT assay, IC50 = 0.19 μM. |
16499324 |
K-562 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human K-562 cells after 72 hrs by MTT assay, IC50 = 1.87 μM. |
16872135 |
LAMA-84 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human LAMA-84 cells after 72 hrs by MTT assay, IC50 = 0.79 μM. |
16872135 |
SKW3 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SKW3 cells after 72 hrs by MTT assay, IC50 = 0.82 μM. |
16872135 |
HL-60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL-60 cells after 72 hrs by MTT assay, IC50 = 10.5 μM. |
16933865 |
HSC2 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human HSC2 cells after 24 hrs by MTT assay, IC50 = 24 μM. |
17125230 |
KB |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB cells after 72 hrs, IC50 = 2 μM. |
17125231 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxic activity against human MCF7 cells after 48 hrs by MTT reduction assay, IC50 = 3.2 μM. |
17316916 |
K562 |
Growth inhibition assay |
|
5 days |
Growth inhibition of K562 cells by XTT assay after 5 days, IC50 = 0.32 μM. |
17411092 |
BV173 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human BV173 cells after 72 hrs by MTT assay, IC50 = 0.9 μM. |
17459529 |
K562 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human K562 cells after 72 hrs by MTT assay, IC50 = 3.1 μM. |
17459529 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by SRB method, IC50 = 0.32 μM. |
17493824 |
HCT15 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HCT15 cells after 48 hrs by SRB method, IC50 = 2.43 μM. |
17493824 |
SK-MEL-2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB method, IC50 = 0.3 μM. |
17493824 |
SKOV3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SKOV3 cells after 48 hrs by SRB method, IC50 = 1.72 μM. |
17493824 |
HL20 |
Growth inhibition assay |
|
48 hrs |
Inhibition of cell growth in human HL20 cells after 48 hrs by MTT assay, IC50 = 0.315 μM. |
17889547 |
HeLa |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of HeLa cells after 48 hrs by MTT assay, GI50 = 8 μM. |
17894480 |
HeLa |
Antitumor assay |
|
72 hrs |
Antitumor activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 3 μM. |
17935309 |
MiaPaCa2 |
Antitumor assay |
|
72 hrs |
Antitumor activity against human MiaPaCa2 cells after 72 hrs by MTT assay, IC50 = 15 μM. |
17935309 |
SW620 |
Antitumor assay |
|
72 hrs |
Antitumor activity against human SW620 cells after 72 hrs by MTT assay, IC50 = 20 μM. |
17935309 |
HL60 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, GI50 = 0.14 μM. |
17962028 |
K562 |
Cytotoxicity assay |
|
5 days |
Cytotoxicity against human K562 cells after 5 days by XTT assay, IC50 = 0.32 μM. |
18076140 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 2.9 μM. |
18258438 |
AGS |
Antitumor assay |
|
72 hrs |
Antitumor against human AGS cells after 72 hrs by MTT assay, IC50 = 0.36 μM. |
18299197 |
HL60 |
Antitumor assay |
|
72 hrs |
Antitumor against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.8 μM. |
18299197 |
J82 |
Antitumor assay |
|
72 hrs |
Antitumor against human J82 cells after 72 hrs by MTT assay, IC50 = 2.8 μM. |
18299197 |
SK-MES1 |
Antitumor assay |
|
72 hrs |
Antitumor against human SK-MES1 cells after 72 hrs by MTT assay, IC50 = 2.5 μM. |
18299197 |
MRC5 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MRC5 cells after 72 hrs by MTT assay, IC50 = 3.9 μM. |
18299197 |
H520 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human H520 cells after 72 hrs by Cell Titer 96 Aqueous Non-Radioactive assay, GI50 = 8.7 μM. |
18321710 |
PC3 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human PC3 cells after 72 hrs by Cell Titer 96 Aqueous Non-Radioactive assay, GI50 = 11.1 μM. |
18321710 |
A549 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human A549 cells after 3 days by SRB assay, IC50 = 1.16 μM. |
18321715 |
HCT15 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human HCT15 cells after 3 days by SRB assay, IC50 = 2.8 μM. |
18321715 |
HL60 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human HL60 cells after 3 days by SRB assay, IC50 = 0.37 μM. |
18321715 |
HT1080 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human HT1080 cells after 3 days by SRB assay, IC50 = 0.25 μM. |
18321715 |
SK-MEL-2 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human SK-MEL-2 cells after 3 days by SRB assay, IC50 = 5.72 μM. |
18321715 |
SKOV3 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human SKOV3 cells after 3 days by SRB assay, IC50 = 4.28 μM. |
18321715 |
SNU638 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human SNU638 cells after 3 days by SRB assay, IC50 = 0.23 μM. |
18321715 |
XF498 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human XF498 cells after 3 days by SRB assay, IC50 = 3.48 μM. |
18321715 |
HL60 |
Apoptosis assay |
|
48 hrs |
Induction of apoptosis in human HL60 cells after 48 hrs, AC50 = 0.4 μM. |
18339455 |
5637 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human 5637 cells after 96 hrs by crystal violet assay, IC50 = 0.54 μM. |
18434163 |
A427 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human A427 cells after 96 hrs by crystal violet assay, IC50 = 0.13 μM. |
18434163 |
KYSE70 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human KYSE70 cells after 96 hrs by crystal violet assay, IC50 = 0.94 μM. |
18434163 |
MCF7 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human MCF7 cells after 96 hrs by crystal violet assay, IC50 = 0.5 μM. |
18434163 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human mitoxantrone-sensitive HL60 cells after 72 hrs, IC50 = 0.486 μM. |
18507368 |
HL60/MX2 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against mitoxantrone-resistant human HL60/MX2 cells after 72 hrs, IC50 = 48.5 μM. |
18507368 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.2 μM. |
18507472 |
HL60 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.315 μM. |
18513974 |
K562 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay, IC50 = 1.27 μM. |
18514972 |
KB |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human KB cells after 48 hrs by MTT assay, IC50 = 0.42 μM. |
18514972 |
L02 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human L02 cells after 48 hrs by MTT assay, IC50 = 13 μM. |
18514972 |
DU145 ATCC HTB 81 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human DU145 ATCC HTB 81 cells after 72 hrs by MTT assay, IC50 = 1.5 μM. |
18558490 |
K562 ATCC CCL 243 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human K562 ATCC CCL 243 cells after 72 hrs by MTT assay, IC50 = 4.9 μM. |
18558490 |
MCF7 ATCC HTB 22 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MCF7 ATCC HTB 22 cells after 72 hrs by MTT assay, IC50 = 12.2 μM. |
18558490 |
U251 RCB 0641 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human U251 RCB 0641 cells after 72 hrs by MTT assay, IC50 = 0.5 μM. |
18558490 |
3LL CRL 1642 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against mouse 3LL CRL 1642 cells after 48 hrs by MTT assay, IC50 = 4 μM. |
18558490 |
L1210 ATCC CCL 219 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against mouse L1210 ATCC CCL 219 cells after 48 hrs by MTT assay, IC50 = 0.5 μM. |
18558490 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 8.37 μM. |
18844422 |
KB |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB cells after 72 hrs by MTT assay, IC50 = 1.25 μM. |
18844422 |
AGS |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human AGS cells after 3 days by MTT assay, IC50 = 0.36 μM. |
19013074 |
HL-60 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human HL-60 cells after 3 days by MTT assay, IC50 = 0.8 μM. |
19013074 |
J82 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human J82 cells after 3 days by MTT assay, IC50 = 2.8 μM. |
19013074 |
MRC5 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human MRC5 cells after 3 days by MTT assay, IC50 = 3.9 μM. |
19013074 |
SK-MES-1 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human SK-MES-1 cells after 3 days by MTT assay, IC50 = 2.5 μM. |
19013074 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 5.9 μM. |
19053514 |
HL-60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL-60 cells after 72 hrs by MTT assay, IC50 = 0.25 μM. |
19053514 |
U937 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human U937 cells after 72 hrs by MTT assay, IC50 = 0.92 μM. |
19053514 |
ACHN |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human ACHN cells after 96 hrs by MTT assay, IC50 = 2.15 μM. |
19053767 |
CCRF-CEM |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human CCRF-CEM cells after 96 hrs by MTT assay, IC50 = 1.2 μM. |
19053767 |
CCRF-SB |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human CCRF-SB cells after 96 hrs by MTT assay, IC50 = 0.1 μM. |
19053767 |
HeLa |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human HeLa cells after 96 hrs by MTT assay, IC50 = 3 μM. |
19053767 |
HT-29 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay, IC50 = 2.5 μM. |
19053767 |
MCF7 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human MCF7 cells after 96 hrs by MTT assay, IC50 = 1 μM. |
19053767 |
MRC5 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human MRC5 cells after 96 hrs by MTT assay, IC50 = 3.9 μM. |
19053767 |
MT4 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human MT4 cells after 96 hrs by MTT assay, IC50 = 1.25 μM. |
19053767 |
SF-268 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human SF-268 cells after 96 hrs by MTT assay, IC50 = 3.25 μM. |
19053767 |
XF498 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human XF498 cells after 96 hrs by MTT assay, IC50 = 3.45 μM. |
19053767 |
KB |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human KB cells after 72 hrs by methylene blue dye assay, IC50 = 1.1 μM. |
19053773 |
KB-TAX50 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human Pgp170 overexpressing multidrug resistant-KB-TAX50 cells after 72 hrs by methylene blue dye assay, IC50 = 3.5 μM. |
19053773 |
KB-VIN10 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human Pgp170 overexpressing multidrug resistant-KB-VIN10 cells after 72 hrs by methylene blue dye assay, IC50 = 23 μM. |
19053773 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by WST-8 assay, IC50 = 1.7 μM. |
19072209 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells after 48 hrs by WST-8 assay, IC50 = 7.6 μM. |
19072209 |
NB4 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human NB4 cells after 48 hrs by WST-8 assay, IC50 = 1.3 μM. |
19072209 |
PC3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human PC3 cells after 48 hrs by WST-8 assay, IC50 = 13.6 μM. |
19072209 |
SH-SY5Y |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SH-SY5Y cells after 48 hrs by WST-8 assay, IC50 = 1.7 μM. |
19072209 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs, IC50 = 1.2 μM. |
19115839 |
DLD1 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human DLD1 cells after 48 hrs, IC50 = 27 μM. |
19115839 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells after 48 hrs, IC50 = 0.7 μM. |
19115839 |
PC3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human PC3 cells after 48 hrs, IC50 = 1.7 μM. |
19115839 |
WS1 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human WS1 cells after 48 hrs, IC50 = 34 μM. |
19115839 |
HL60 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 3.3 μM. |
19251420 |
AGS |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human AGS cells after 72 hrs by MTT assay, IC50 = 0.36 μM. |
19269832 |
J82 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human J82 cells after 72 hrs by MTT assay, IC50 = 2.8 μM. |
19269832 |
MRC5 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MRC5 cells after 72 hrs by MTT assay, IC50 = 3.9 μM. |
19269832 |
SKMES1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SKMES1 cells after 72 hrs by MTT assay, IC50 = 2.5 μM. |
19269832 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 14.3 μM. |
19394829 |
CCRF-CEM |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human CCRF-CEM cells after 72 hrs by MTT assay, IC50 = 1.1 μM. |
19394829 |
HeLa |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 3.9 μM. |
19394829 |
Jurkat |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human Jurkat cells after 72 hrs by MTT assay, IC50 = 1.2 μM. |
19394829 |
MCF7 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 10.9 μM. |
19394829 |
MDA-MB-231 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay, IC50 = 21.2 μM. |
19394829 |
AGS |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human AGS cells after 3 days by MTT assay, IC50 = 0.36 μM. |
19419803 |
HL60 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human HL60 cells after 3 days by MTT assay, IC50 = 0.8 μM. |
19419803 |
J82 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human J82 cells after 3 days by MTT assay, IC50 = 2.5 μM. |
19419803 |
MRC5 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human MRC5 cells after 3 days by MTT assay, IC50 = 3.93 μM. |
19419803 |
SKMES1 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human SKMES1 cells after 3 days by MTT assay, IC50 = 2.8 μM. |
19419803 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by SRB method, IC50 = 1.7 μM. |
19425589 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells after 48 hrs by SRB method, IC50 = 7.6 μM. |
19425589 |
NB4 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human NB4 cells after 48 hrs by SRB method, IC50 = 1.3 μM. |
19425589 |
PC3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human PC3 cells after 48 hrs by SRB method, IC50 = 13.6 μM. |
19425589 |
SH-SY5Y |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SH-SY5Y cells after 48 hrs by SRB method, IC50 = 1.7 μM. |
19425589 |
HT-29 |
Cytotoxicity assay |
|
96 hrs |
Cytotoxicity against human HT-29 cells after 96 hrs by SRB assay, GI50 = 0.73 μM. |
19572549 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 0.63 μM. |
19685913 |
Bel7402 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 1.03 μM. |
19685913 |
HL60 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human HL60 cells after 24 hrs by SRB assay, IC50 = 0.042 μM. |
19685913 |
P388 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against mouse P388 cells after 24 hrs by SRB assay, IC50 = 0.05 μM. |
19685913 |
HCT116 |
Antiproliferative assay |
|
3 days |
Antiproliferative activity against human HCT116 cells after 3 days by XTT assay, IC50 = 1.7 μM. |
19691293 |
SW948 |
Antiproliferative assay |
|
3 days |
Antiproliferative activity against human SW948 cells after 3 days by XTT assay, IC50 = 1.3 μM. |
19691293 |
A549 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human A549 cells after 24 hrs by SRB assay, IC50 = 0.63 μM. |
19769341 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.042 μM. |
19769341 |
HONE1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HONE1 cells after 72 hrs by methylene blue dye assay, IC50 = 1.2 μM. |
19785430 |
HT-29 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HT-29 cells after 72 hrs by methylene blue dye assay, IC50 = 2.3 μM. |
19785430 |
KB |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB cells after 72 hrs by methylene blue dye assay, IC50 = 1.3 μM. |
19785430 |
HCT116 |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human HCT116 cells after 4 days, IC50 = 14.39 μM. |
19800803 |
HaCaT |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HaCaT cells after 72 hrs by MTT assay, IC50 = 0.55 μM. |
19919064 |
B16 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against mouse B16 cells after 72 hrs by MTT assay, IC50 = 0.28 μM. |
19919064 |
DU145 |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human DU145 cells after 4 days by ELISA reader assay, IC50 = 1.3 μM. |
19939682 |
HCT15 |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human HCT15 cells after 4 days by ELISA reader assay, IC50 = 1.09 μM. |
19939682 |
HeLa |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human HeLa cells after 4 days by ELISA reader assay, IC50 = 1.29 μM. |
19939682 |
K562 |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human K562 cells after 4 days by ELISA reader assay, IC50 = 2.41 μM. |
19939682 |
MCF7 |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human MCF7 cells after 4 days by ELISA reader assay, IC50 = 1.89 μM. |
19939682 |
DU145 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human DU145 cells after 3 days, IC50 = 21.07 μM. |
19954977 |
HCT116 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human HCT116 cells after 3 days, IC50 = 17.92 μM. |
19954977 |
HeLa |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human HeLa cells after 3 days, IC50 = 8.43 μM. |
19954977 |
MCF7 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human MCF7 cells after 3 days, IC50 = 18.01 μM. |
19954977 |
MDA-MB-231 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human MDA-MB-231 cells after 3 days, IC50 = 16.85 μM. |
19954977 |
K562 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human K562 cells after 72 hrs by MTS assay, IC50 = 0.42 μM. |
20006518 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs, IC50 = 0.29 μM. |
20053564 |
HL60 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL60 cells after 48 hrs, IC50 = 0.42 μM. |
20053564 |
RPMI8226 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human RPMI8226 cells after 48 hrs, IC50 = 0.14 μM. |
20053564 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 0.83 μM. |
20071056 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60 cells after 72 hrs by CCK8 method, IC50 = 0.18 μM. |
20071056 |
RPMI8226 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human RPMI8226 cells after 72 hrs by CCK8 method, IC50 = 0.7 μM. |
20071056 |
DU145 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human DU145 cells after 48 hrs by MTT assay, IC50 = 1.63 μM. |
20093033 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 0.47 μM. |
20093033 |
HL60 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.97 μM. |
20093033 |
HT-29 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 1.42 μM. |
20093033 |
MDA-MB-231 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 2.87 μM. |
20093033 |
KB |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB cells after 72 hrs by MTT assay, ED50 = 0.2 μM. |
20187635 |
KB |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB cells after 72 hrs by MTT assay, IC50 = 0.6 μM. |
20187635 |
KB1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB1 cells after 72 hrs by MTT assay, IC50 = 34.8 μM. |
20187635 |
KB-7d |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB-7d cells after 72 hrs by MTT assay, ED50 = 25 μM. |
20187635 |
KB |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human vincristine-resistant KB cells after 72 hrs by MTT assay, IC50 = 28.7 μM. |
20187635 |
NCI-H460 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human NCI-H460 cells after 48 hrs by [3H]thymidine incorporation assay, IC50 = 0.09 μM. |
20210346 |
SKHEP1 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SKHEP1 cells after 48 hrs by [3H]thymidine incorporation assay, IC50 = 0.062 μM. |
20210346 |
U87MG |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human U87MG cells after 48 hrs by [3H]thymidine incorporation assay, IC50 = 0.145 μM. |
20210346 |
HepG2 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human HepG2 cells after 72 hrs by sulforhodamine B assay, IC50 = 4.1 μM. |
20346660 |
DU145 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human DU145 cells after 2 days by automatic ELISA reader system, IC50 = 0.5 μM. |
20392646 |
HCT15 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HCT15 cells after 2 days by automatic ELISA reader system, IC50 = 1.1 μM. |
20392646 |
HeLa |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HeLa cells after 2 days by automatic ELISA reader system, IC50 = 1.4 μM. |
20392646 |
HL60 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HL60 cells after 2 days by automatic ELISA reader system, IC50 = 1 μM. |
20392646 |
MDA-MB-231 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human MDA-MB-231 cells after 2 days by automatic ELISA reader system, IC50 = 0.7 μM. |
20392646 |
HM-SFME-1 |
Antiproliferative assay |
|
24 hrs |
Antiproliferative activity against mouse r/m HM-SFME-1 cells after 24 hrs by MTT assay, IC50 = 9 μM. |
20398972 |
SFME |
Antiproliferative assay |
|
24 hrs |
Antiproliferative activity against mouse SFME cells after 24 hrs by MTT assay, IC50 = 0.5 μM. |
20398972 |
HT-29 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 30.38 μM. |
20405844 |
MDA-MB-231 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 23.22 μM. |
20405844 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by resazurin reduction assay, IC50 = 16 μM. |
20413315 |
DLD1 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human DLD1 cells after 48 hrs by resazurin reduction assay, IC50 = 10 μM. |
20413315 |
WS1 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human WS1 cells after 48 hrs by resazurin reduction assay, IC50 = 4.3 μM. |
20413315 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by SRB assay, IC50 = 0.63 μM. |
20415462 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.042 μM. |
20415462 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.39 μM. |
20524638 |
HL60/MX2 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60/MX2 cells after 72 hrs by MTT assay, IC50 = 11.9 μM. |
20570510 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human topoisomerase 2-sensitive HL60 cells after 72 hrs by MTT assay, IC50 = 1.3 μM. |
20570510 |
A375 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity activity against human A375 cells after 24 hrs by NRU assay, IC50 = 19 μM. |
20570625 |
A375 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity activity against human A375 cells after 48 hrs by NRU assay, IC50 = 12 μM. |
20570625 |
B16 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity activity against mouse B16 cells after 24 hrs by NRU assay, IC50 = 9 μM. |
20570625 |
B16 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity activity against mouse B16 cells after 48 hrs by NRU assay, IC50 = 0.13 μM. |
20570625 |
DU145 |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human DU145 cells after 4 days by MTT assay, IC50 = 13.8 μM. |
20619511 |
HCT116 |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human HCT116 cells after 4 days by MTT assay, IC50 = 11.9 μM. |
20619511 |
HeLa |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human HeLa cells after 4 days by MTT assay, IC50 = 18.2 μM. |
20619511 |
MCF7 |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human MCF7 cells after 4 days by MTT assay, IC50 = 17.5 μM. |
20619511 |
MDA-MB-231 |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human MDA-MB-231 cells after 4 days by MTT assay, IC50 = 16.3 μM. |
20619511 |
AGS |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human AGS cells after 72 hrs by MTT assay, IC50 = 0.36 μM. |
20828890 |
HL-60(TB) |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL-60(TB) cells after 72 hrs by MTT assay, IC50 = 0.8 μM. |
20828890 |
J82 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human J82 cells after 72 hrs by MTT assay, IC50 = 2.8 μM. |
20828890 |
MRC5 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MRC5 cells after 72 hrs by MTT assay, IC50 = 3.9 μM. |
20828890 |
SKMES1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SKMES1 cells after 72 hrs by MTT assay, IC50 = 2.5 μM. |
20828890 |
colon cancer cells |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human colon cancer cells after 72 hrs by sulforhodamine B assay, GI50 = 1.3 μM. |
20884089 |
gastric cancer cells |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human gastric cancer cells after 72 hrs by sulforhodamine B assay, GI50 = 1.3 μM. |
20884089 |
lung cancer cells |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human lung cancer cells after 72 hrs by sulforhodamine B assay, GI50 = 1.3 μM. |
20884089 |
HCT15 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HCT15 cells after 48 hrs by sulforhodamine B assay, IC50 = 1.6 μM. |
20939516 |
MESSA |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human MESSA cells after 48 hrs by sulforhodamine B assay, IC50 = 0.3 μM. |
20939516 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60 cells after 72 hrs, IC50 = 0.486 μM. |
20961767 |
HL60/MX2 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60/MX2 cells after 72 hrs, IC50 = 48.5 μM. |
20961767 |
KB |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human KB cells after 3 days by sulforhodamine B assay, EC50 = 4.5 μM. |
21028898 |
502713 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human 502713 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 0.1 μM. |
21074444 |
A549 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human A549 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 3.08 μM. |
21074444 |
DU145 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 3.7 μM. |
21074444 |
HCT15 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human HCT15 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 0.9 μM. |
21074444 |
Hep2 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human Hep2 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 0.9 μM. |
21074444 |
IMR32 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human IMR32 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 6.3 μM. |
21074444 |
PC3 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human PC3 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 2.6 μM. |
21074444 |
HT-29 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay, GI50 = 31.62 μM. |
21115210 |
K562 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human K562 cells after 72 hrs by MTT assay, GI50 = 12.59 μM. |
21115210 |
MCF7 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, GI50 = 19.95 μM. |
21115210 |
PC3 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human PC3 cells after 72 hrs by MTT assay, GI50 = 0.63 μM. |
21115210 |
PC3 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human PC3 cells after 72 hrs by MTT assay, TGI = 3.98 μM. |
21115210 |
95-D |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human 95-D cells after 72 hrs by MTT assay, IC50 = 0.0202 μM. |
21145139 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 0.00256 μM. |
21145139 |
KB |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB cells after 72 hrs by MTT assay, IC50 = 0.00461 μM. |
21145139 |
KB/VCR |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB/VCR cells after 72 hrs by MTT assay, IC50 = 0.0834 μM. |
21145139 |
A549 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human A549 cells assessed as cell growth inhibition after 3 days by MTT assay, IC50 = 21.4 μM. |
21277655 |
HCT116 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 3 days by MTT assay, IC50 = 13.5 μM. |
21277655 |
HepG2 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition after 3 days by MTT assay, IC50 = 4.9 μM. |
21277655 |
HT1080 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human HT1080 cells after 96 hrs by MTT assay, IC50 = 0.75 μM. |
21296467 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 11 μM. |
21397370 |
A2780 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A2780 cells after 48 hrs by sulforhodamine B based ELISA, GI50 = 1.3 μM. |
21402478 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B based ELISA, GI50 = 3.08 μM. |
21402478 |
COLO205 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B based ELISA, GI50 = 0.13 μM. |
21402478 |
KB |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human KB cells after 48 hrs by sulforhodamine B based ELISA, GI50 = 0.3 μM. |
21402478 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells after 48 hrs by sulforhodamine B based ELISA, GI50 = 2.1 μM. |
21402478 |
DU145 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human DU145 cells after 2 days, IC50 = 2.19 μM. |
21419530 |
HCT116 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HCT116 cells after 2 days, IC50 = 9.5 μM. |
21419530 |
HeLa |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HeLa cells after 2 days, IC50 = 2.36 μM. |
21419530 |
HL60 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HL60 cells after 2 days, IC50 = 1.28 μM. |
21419530 |
MDA-MB-231 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human MDA-MB-231 cells after 2 days, IC50 = 1.23 μM. |
21419530 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay, IC50 = 5.62 μM. |
21477899 |
HCT15 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay, IC50 = 7.15 μM. |
21477899 |
Hep2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human Hep2 cells after 48 hrs by sulforhodamine B assay, IC50 = 2.15 μM. |
21477899 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells after 48 hrs by sulforhodamine B assay, IC50 = 19 μM. |
21477899 |
PC3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay, IC50 = 17.5 μM. |
21477899 |
SF295 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SF295 cells after 48 hrs by sulforhodamine B assay, IC50 = 13.5 μM. |
21477899 |
A2780 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.3 μM. |
21489802 |
A549 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.08 μM. |
21489802 |
COLO205 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.13 μM. |
21489802 |
DWD |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human DWD cells after 48 hrs by sulforhodamine B assay, GI50 = 0.6 μM. |
21489802 |
Gurav |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human Gurav cells after 48 hrs by sulforhodamine B assay, GI50 = 0.5 μM. |
21489802 |
HOP62 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.8 μM. |
21489802 |
KB |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human KB cells after 48 hrs by sulforhodamine B assay, GI50 = 0.3 μM. |
21489802 |
MCF7 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.1 μM. |
21489802 |
PC3 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.6 μM. |
21489802 |
SiHa |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human SiHa cells after 48 hrs by sulforhodamine B assay, GI50 = 3.1 μM. |
21489802 |
ZR-75-1 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human ZR-75-1 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.2 μM. |
21489802 |
HeLa |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 4 μM. |
21570846 |
KB |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB cells after 72 hrs by MTT assay, IC50 = 10 μM. |
21570846 |
DU145 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human DU145 cells after 2 days, IC50 = 0.5 μM. |
21601964 |
HCT15 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HCT15 cells after 2 days, IC50 = 1.1 μM. |
21601964 |
HeLa |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HeLa cells after 2 days, IC50 = 1.4 μM. |
21601964 |
HL60 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HL60 cells after 2 days, IC50 = 1 μM. |
21601964 |
MDA-MB-231 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human MDA-MB-231 cells after 2 days, INH = 0.7 μM. |
21601964 |
AGS |
Anticancer assay |
|
3 days |
Anticancer activity against human AGS cells after 3 days by MTT assay, IC50 = 0.36 μM. |
21621882 |
J82 |
Anticancer assay |
|
3 days |
Anticancer activity against human J82 cells after 3 days by MTT assay, IC50 = 0.8 μM. |
21621882 |
MRC5 |
Anticancer assay |
|
3 days |
Anticancer activity against human MRC5 cells after 3 days by MTT assay, IC50 = 3.9 μM. |
21621882 |
SKMES1 |
Anticancer assay |
|
3 days |
Anticancer activity against human SKMES1 cells after 3 days by MTT assay, IC50 = 2.8 μM. |
21621882 |
Caco2 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human Caco2 cells after 72 hrs by MTS assay, IC50 = 18.6 μM. |
21724394 |
CCD-18Co |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human CCD-18Co cells after 72 hrs by MTS assay, IC50 = 44.4 μM. |
21724394 |
HCT116 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay, IC50 = 25.5 μM. |
21724394 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 14.8 μM. |
21733601 |
SiHa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SiHa cells after 48 hrs by MTT assay, IC50 = 30.7 μM. |
21733601 |
A2780 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A2780 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.3 μM. |
21737288 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.08 μM. |
21737288 |
COLO205 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.13 μM. |
21737288 |
DWD |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human DWD cells after 48 hrs by sulforhodamine B assay, GI50 = 0.6 μM. |
21737288 |
Gurav |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human Gurav cells after 48 hrs by sulforhodamine B assay, GI50 = 0.5 μM. |
21737288 |
HOP62 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.8 μM. |
21737288 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.1 μM. |
21737288 |
ZR-75-1 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human ZR-75-1 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.2 μM. |
21737288 |
CCRF-CEM |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human CCRF-CEM cells after 96 hrs by MTT assay, CC50 = 0.09 μM. |
21741130 |
CCRF-SB |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human CCRF-SB cells after 96 hrs by MTT assay, CC50 = 0.1 μM. |
21741130 |
DU145 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human DU145 cells after 96 hrs by MTT assay, CC50 = 0.4 μM. |
21741130 |
HepG2 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human HepG2 cells after 96 hrs by MTT assay, CC50 = 0.7 μM. |
21741130 |
MCF7 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human MCF7 cells after 96 hrs by MTT assay, CC50 = 1 μM. |
21741130 |
SK-MEL-28 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human SK-MEL-28 cells after 96 hrs by MTT assay, CC50 = 1.2 μM. |
21741130 |
SKMES1 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human SKMES1 cells after 96 hrs by MTT assay, CC50 = 0.3 μM. |
21741130 |
WIL2-NS |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human WIL2-NS cells after 96 hrs by MTT assay, CC50 = 0.2 μM. |
21741130 |
MT4 |
Cytotoxicity assay |
|
96 hrs |
Cytotoxicity against human MT4 cells infected with HTLV-1 after 96 hrs by MTT assay, CC50 = 0.09 μM. |
21741130 |
HeLa |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HeLa cells after 2 days by MTT assay, IC50 = 6.27 μM. |
21821321 |
K562 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human K562 cells after 2 days by MTT assay, IC50 = 2.11 μM. |
21821321 |
HeLa |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human HeLa cells assessed as inhibition of cell viability after 24 hrs by MTT assay, IC50 = 23.33 μM. |
21983445 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 24.9 μM. |
22041063 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by CCK-8 assay, IC50 = 2.76 μM. |
22041063 |
HL60 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by CCK-8 assay, IC50 = 2.85 μM. |
22041063 |
SiHa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SiHa cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 40.4 μM. |
22041063 |
KB |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human KB cells after 72 hrs by methylene blue assay, IC50 = 1.1 μM. |
22060033 |
KB-S15 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human KB-S15 cells after 72 hrs by methylene blue assay, IC50 = 3.5 μM. |
22060033 |
KB-VIN10 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human KB-VIN10 cells after 72 hrs by methylene blue assay, IC50 = 23 μM. |
22060033 |
CCRF-CEM |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human CCRF-CEM cells after 72 hrs by MTT assay, GI50 = 12.59 μM. |
22104973 |
HT-29 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay, GI50 = 31.62 μM. |
22104973 |
MCF7 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, GI50 = 19.95 μM. |
22104973 |
THP1 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human THP1 cells after 48 hrs by MTT assay, IC50 = 2.16 μM. |
22115593 |
U937 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human U937 cells after 48 hrs by MTT assay, IC50 = 17.94 μM. |
22115593 |
B16F10 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against mouse B16F10 cells after 48 hrs by MTT assay, IC50 = 18.69 μM. |
22115593 |
HCT116 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HCT116 cells after 72 hrs by sulforhodamine B and MTT assay, IC50 = 0.91 μM. |
22119124 |
K562 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human K562 cells after 72 hrs by sulforhodamine B and MTT assay, IC50 = 5.16 μM. |
22119124 |
KB |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B and MTT assay, IC50 = 0.85 μM. |
22119124 |
MCF7 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B and MTT assay, IC50 = 1.09 μM. |
22119124 |
A375 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human A375 cells after 48 hrs by MTT assay, IC50 = 1.39 μM. |
22136907 |
A549 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human A549 cells after 48 hrs by MTT assay, IC50 = 2.34 μM. |
22136907 |
ACHN |
Anticancer assay |
|
48 hrs |
Anticancer activity against human ACHN cells after 48 hrs by MTT assay, IC50 = 7.61 μM. |
22136907 |
HT-29 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 1.81 μM. |
22136907 |
MCF7 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 0.68 μM. |
22136907 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 24.9 μM. |
22244588 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells after 48 hrs by CCK-8 assay, IC50 = 40.4 μM. |
22244588 |
HL60 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL60 cells after 48 hrs by CCK-8 assay, IC50 = 2.85 μM. |
22244588 |
SiHa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SiHa cells after 48 hrs by MTT assay, IC50 = 2.76 μM. |
22244588 |
DU145 |
Cytotoxicity assay |
|
96 hrs |
Cytotoxicity against human DU145 cells after 96 hrs, IC50 = 3 μM. |
22276775 |
HepG2 |
Cytotoxicity assay |
|
96 hrs |
Cytotoxicity against human HepG2 cells after 96 hrs, IC50 = 4 μM. |
22276775 |
MT4 |
Cytotoxicity assay |
|
96 hrs |
Cytotoxicity against human MT4 cells after 96 hrs, IC50 = 0.09 μM. |
22276775 |
DU145 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human DU145 cells after 2 days, IC50 = 2.94 μM. |
22318164 |
HCT15 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HCT15 cells after 2 days, IC50 = 1.33 μM. |
22318164 |
HeLa |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HeLa cells after 2 days, IC50 = 3.2 μM. |
22318164 |
K562 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human K562 cells after 2 days, IC50 = 2.09 μM. |
22318164 |
MCF7 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human MCF7 cells after 2 days, IC50 = 3.25 μM. |
22318164 |
A549 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human A549 cells after 2 days by MTT assay, IC50 = 9.51 μM. |
22325897 |
HL60 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HL60 cells after 2 days by MTT assay, IC50 = 1.83 μM. |
22325897 |
Jurkat |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human Jurkat cells after 2 days by MTT assay, IC50 = 5.35 μM. |
22325897 |
THP1 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human THP1 cells after 2 days by MTT assay, IC50 = 2.16 μM. |
22325897 |
U937 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human U937 cells after 2 days by MTT assay, IC50 = 17.94 μM. |
22325897 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 23.8 μM. |
22342101 |
Hep3B |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human Hep3B cells after 72 hrs by MTT assay, IC50 = 6.7 μM. |
22342101 |
U87 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human U87 cells after 72 hrs by MTT assay, IC50 = 12.4 μM. |
22342101 |
A2780 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.31 μM. |
22364746 |
A549 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.08 μM. |
22364746 |
COLO205 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.13 μM. |
22364746 |
DWD |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human DWD cells after 48 hrs by sulforhodamine B assay, GI50 = 0.62 μM. |
22364746 |
HOP62 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.8 μM. |
22364746 |
KB |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human KB cells after 48 hrs by sulforhodamine B assay, GI50 = 0.31 μM. |
22364746 |
MCF7 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.11 μM. |
22364746 |
ZR-75-1 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human ZR-75-1 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.2 μM. |
22364746 |
Vero |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against african green monkey Vero cells after 48 hrs by MTT assay, LC50 = 18 μM. |
22381050 |
HEK293 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HEK293 cells after 48 hrs by MTT assay, LC50 = 28 μM. |
22381050 |
DU145 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human DU145 cells after 2 days by cell counting kit-8 analysis, IC50 = 1.21 μM. |
22503656 |
HCT15 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HCT15 cells after 2 days by cell counting kit-8 analysis, IC50 = 1.17 μM. |
22503656 |
HEK293 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HEK293 cells after 2 days by cell counting kit-8 analysis, IC50 = 1.21 μM. |
22503656 |
T47D |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human T47D cells after 2 days by cell counting kit-8 analysis, IC50 = 2.39 μM. |
22503656 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 0.48 μM. |
22564383 |
T98G |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human T98G cells expressing mutant p53 after 48 hrs by MTT assay, IC50 = 0.46 μM. |
22564383 |
U87 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human U87 cells expressing wild-type p53 after 48 hrs by MTT assay, IC50 = 0.62 μM. |
22564383 |
COLO205 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human COLO205 cells after 48 hrs by MTT assay, IC50 = 0.43 μM. |
22578452 |
HepG2 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 4.76 μM. |
22578452 |
THP1 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human THP1 cells after 48 hrs by MTT assay, IC50 = 2.16 μM. |
22578452 |
U937 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human U937 cells after 48 hrs by MTT assay, IC50 = 17.96 μM. |
22578452 |
B16F10 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay, IC50 = 18.71 μM. |
22578452 |
CCRF-CEM |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human CCRF-CEM cells assessed as cell viability after 48 hrs by celltiter-blue assay, IC50 = 0.24 μM. |
22582991 |
HL60 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL60 cells assessed as cell viability after 48 hrs by celltiter-blue assay, IC50 = 0.11 μM. |
22582991 |
K562 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human K562 cells assessed as cell viability after 48 hrs by celltiter-blue assay, IC50 = 2.3 μM. |
22582991 |
HeLa |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay, GI50 = 3.56 μM. |
22682920 |
HeLa |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay, TGI = 40.18 μM. |
22682920 |
MCF7 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human MCF7 cells after 48 hrs by SRB assay, GI50 = 0.56 μM. |
22682920 |
TK10 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human TK10 cells after 48 hrs by SRB assay, GI50 = 7.19 μM. |
22682920 |
TK10 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human TK10 cells after 48 hrs by SRB assay, TGI = 49.74 μM. |
22682920 |
UACC62 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human UACC62 cells after 48 hrs by SRB assay, GI50 = 0.89 μM. |
22682920 |
Vero |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay, IC50 = 31.14 μM. |
22687745 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 10.12 μM. |
22687745 |
HepG2 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 5.48 μM. |
22687745 |
SGC7901 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 12.09 μM. |
22687745 |
SH-SY5Y |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay, IC50 = 5.37 μM. |
22687745 |
L929 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against mouse L929 cells after 72 hrs by MTT assay, IC50 = 1 μM. |
22687745 |
KBCPT100 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human camptothecin-resistant KBCPT100 cells after 72 hrs by ethylene blue dye assay, IC50 = 0.336 μM. |
22698783 |
KB |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human KB cells after 72 hrs by ethylene blue dye assay, IC50 = 0.475 μM. |
22698783 |
KBCPT100 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human partially revertant camptothecin-resistant KBCPT100 cells after 72 hrs by ethylene blue dye assay, IC50 = 0.374 μM. |
22698783 |
DU145 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human DU145 cells after 72 hrs by MTT assay, IC50 = 1.42 μM. |
22819942 |
HCT15 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay, IC50 = 0.28 μM. |
22819942 |
HEK293 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HEK293 cells after 72 hrs by MTT assay, IC50 = 0.41 μM. |
22819942 |
T47D |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human T47D cells after 72 hrs by MTT assay, IC50 = 1.21 μM. |
22819942 |
A549 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity at human A549 cells after 72 hrs by MTT assay, IC50 = 0.8 μM. |
22861499 |
DMS53 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity at human DMS53 cells after 72 hrs by MTT assay, IC50 = 1.5 μM. |
22861499 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.83 μM. |
22889556 |
TK10 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human TK10 cells after 48 hrs by sulforhodamine B assay, GI50 = 5.89 μM. |
22889556 |
TK10 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human TK10 cells after 48 hrs by sulforhodamine B assay, TGI = 43.33 μM. |
22889556 |
UACC62 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human UACC62 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.41 μM. |
22889556 |
UACC62 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human UACC62 cells after 48 hrs by sulforhodamine B assay, TGI = 4 μM. |
22889556 |
DOGUM |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human DOGUM cells after 72 hrs by MTT assay, IC50 = 0.075 μM. |
23031590 |
DOGUM |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human etoposide-resistant DOGUM cells after 72 hrs by MTT assay, IC50 = 0.28 μM. |
23031590 |
GUMBUS |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human etoposide-resistant GUMBUS cells after 72 hrs by MTT assay, IC50 = 0.57 μM. |
23031590 |
GUMBUS |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human GUMBUS cells after 72 hrs by MTT assay, IC50 = 0.042 μM. |
23031590 |
A549 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human A549 cells after 72 hrs by SRB assay, GI50 = 2.2 μM. |
23153810 |
HT-29 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human HT-29 cells after 72 hrs by SRB assay, GI50 = 9.4 μM. |
23153810 |
MDA-MB-231 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human MDA-MB-231 cells after 72 hrs by SRB assay, GI50 = 7.2 μM. |
23153810 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 2.8 μM. |
23182091 |
ACHN |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human ACHN cells after 72 hrs by MTT assay, IC50 = 7.61 μM. |
23182091 |
HeLa |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 1.52 μM. |
23182091 |
HT-29 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay, IC50 = 1.81 μM. |
23182091 |
B16 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against mouse B16 cells after 72 hrs by MTT assay, IC50 = 1.39 μM. |
23182091 |
HeLa |
Antitumor assay |
|
48 hrs |
Antitumor activity against human HeLa cells assessed as growth inhibition measured after 48 hrs by MTT assay, IC50 = 8.32 μM. |
23313635 |
HepG2 |
Antitumor assay |
|
48 hrs |
Antitumor activity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay, IC50 = 9.14 μM. |
23313635 |
Vero |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against african green monkey Vero cells after 48 hrs by MTT assay, LC50 = 29 μM. |
23321564 |
HEK293 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against HEK293 cells after 48 hrs by MTT assay, LC50 = 17 μM. |
23321564 |
BGC832 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human BGC832 cells after 24 hrs by MTT assay, IC50 = 26.85 μM. |
23369687 |
HeLa |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human HeLa cells after 24 hrs by MTT assay, IC50 = 17.68 μM. |
23369687 |
K562 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human K562 cells after 24 hrs by MTT assay, IC50 = 2.85 μM. |
23369687 |
AGS |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human AGS cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 0.36 μM. |
23454511 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 1.8 μM. |
23454511 |
J82 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human J82 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 2.8 μM. |
23454511 |
MRC5 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MRC5 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 3.9 μM. |
23454511 |
SKMES1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SKMES1 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 2.5 μM. |
23454511 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by SRB assay, IC50 = 2.58 μM. |
23490151 |
DU145 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human DU145 cells after 72 hrs by SRB assay, IC50 = 2.03 μM. |
23490151 |
KB |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB cells after 72 hrs by SRB assay, IC50 = 3.88 μM. |
23490151 |
HepG2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 6.41 μM. |
23668986 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 3.2 μM. |
23711769 |
HCT8 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HCT8 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 7.06 μM. |
23711769 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 2.91 μM. |
23711769 |
HL60 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by CCK-8 assay, IC50 = 1.15 μM. |
23711769 |
HT-29 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay, GI50 = 31.62 μM. |
23831811 |
MCF7 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, GI50 = 19.95 μM. |
23831811 |
A2780 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.31 μM. |
23849207 |
A549 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.08 μM. |
23849207 |
COLO205 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.13 μM. |
23849207 |
DWD |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human DWD cells after 48 hrs by sulforhodamine B assay, GI50 = 0.62 μM. |
23849207 |
Gurav |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human Gurav cells after 48 hrs by sulforhodamine B assay, GI50 = 0.51 μM. |
23849207 |
HOP62 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.8 μM. |
23849207 |
KB |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human KB cells after 48 hrs by sulforhodamine B assay, GI50 = 0.31 μM. |
23849207 |
MCF7 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.11 μM. |
23849207 |
SiHa |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human SiHa cells after 48 hrs by sulforhodamine B assay, GI50 = 3.11 μM. |
23849207 |
ZR-75-1 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human ZR-75-1 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.2 μM. |
23849207 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.5 μM. |
23865778 |
U937 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human U937 cells after 72 hrs by MTT assay, IC50 = 1.4 μM. |
23865778 |
H460 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human H460 cells after 48 hrs by MTT assay, IC50 = 1 μM. |
23867385 |
HL60 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 5.48 μM. |
23867385 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 32.05 μM. |
23968711 |
HL60 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.33 μM. |
23968711 |
K562 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human K562 cells after 48 hrs by MTT assay, IC50 = 8.45 μM. |
23968711 |
MCF10A |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MCF10A cells after 72 hrs by MTT assay, IC50 = 36.26 μM. |
23999041 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay, GI50 = 0.87 μM. |
23999041 |
MCF7 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 1.2 μM. |
23999041 |
MDA-MB-231 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by SRB assay, GI50 = 1.67 μM. |
23999041 |
MDA-MB-231 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay, IC50 = 1.5 μM. |
23999041 |
A549 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 14.3 μM. |
24012378 |
CCRF-CEM |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human CCRF-CEM cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 1.1 μM. |
24012378 |
HeLa |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 3.9 μM. |
24012378 |
Jurkat |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human Jurkat cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 1.2 μM. |
24012378 |
MCF7 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 10.9 μM. |
24012378 |
MDA-MB-231 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human MDA-MB-231 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 21.2 μM. |
24012378 |
HEK293 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against HEK293 cells after 2 days by CCK-8 assay, IC50 = 0.72 μM. |
24013413 |
DU145 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human DU145 cells after 2 days by CCK-8 assay, IC50 = 9.29 μM. |
24013413 |
HCT15 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HCT15 cells after 2 days by CCK-8 assay, IC50 = 5.12 μM. |
24013413 |
T47D |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human T47D cells after 2 days by CCK-8 assay, IC50 = 3.42 μM. |
24013413 |
A549 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 1.71 μM. |
24095018 |
HCT116 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 0.87 μM. |
24095018 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 14.9 μM. |
24095019 |
HCT8 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HCT8 cells after 48 hrs by MTT assay, IC50 = 6.54 μM. |
24095019 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 4.73 μM. |
24095019 |
HepG2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 11.52 μM. |
24095019 |
KB |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB cells assessed as growth inhibition after 72 hrs by methylene blue staining-based assay, IC50 = 1.1 μM. |
24106982 |
KB-S15 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB-S15 cells overexpressing P-gp170/MDR assessed as growth inhibition after 72 hrs by methylene blue staining-based assay, IC50 = 3.5 μM. |
24106982 |
KB-VIN10 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB-VIN10 cells overexpressing P-gp170/MDR assessed as growth inhibition after 72 hrs by methylene blue staining-based assay, IC50 = 23 μM. |
24106982 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 3.2 μM. |
24140948 |
HCT8 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HCT8 cells after 48 hrs by MTT assay, IC50 = 7.06 μM. |
24140948 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 2.91 μM. |
24140948 |
HL60 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL60 cells after 48 hrs by cell counting kit-8 assay, IC50 = 1.15 μM. |
24140948 |
A549 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human A549 cells after 72 hrs by MTT assay, IC50 = 2 μM. |
24180210 |
Hs683 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human Hs683 cells after 72 hrs by MTT assay, IC50 = 2 μM. |
24180210 |
MCF7 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human MCF7 cells after 72 hrs by MTT assay, IC50 = 4 μM. |
24180210 |
SK-MEL-28 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human SK-MEL-28 cells after 72 hrs by MTT assay, IC50 = 3 μM. |
24180210 |
U373 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human U373 cells after 72 hrs by MTT assay, IC50 = 25 μM. |
24180210 |
HBL100 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human HBL100 cells after 48 hrs by SRB assay, GI50 = 1.4 μM. |
24211632 |
HeLa |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human HeLa cells after 48 hrs by SRB assay, GI50 = 3.3 μM. |
24211632 |
SW1573 |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human SW1573 cells after 48 hrs by SRB assay, GI50 = 15 μM. |
24211632 |
T47D |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human T47D cells after 48 hrs by SRB assay, GI50 = 22 μM. |
24211632 |
WiDr |
Growth inhibition assay |
|
48 hrs |
Growth inhibition of human WiDr cells after 48 hrs by SRB assay, GI50 = 23 μM. |
24211632 |
HCT116 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTS assay, IC50 = 1 μM. |
24328269 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay, IC50 = 2.58 μM. |
24332656 |
DU145 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human DU145 cells after 72 hrs by sulforhodamine B assay, IC50 = 2.03 μM. |
24332656 |
KB |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B assay, IC50 = 3.88 μM. |
24332656 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by MTT assay relative to untreated control, GI50 = 4.46 μM. |
24389510 |
HT-29 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay relative to untreated control, GI50 = 31.62 μM. |
24389510 |
MCF7 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay relative to untreated control, GI50 = 19.95 μM. |
24389510 |
PC3 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human PC3 cells after 72 hrs by MTT assay relative to untreated control, GI50 = 0.63 μM. |
24389510 |
PC3 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human PC3 cells after 72 hrs by MTT assay relative to untreated control, TGI = 3.98 μM. |
24389510 |
RWPE1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human RWPE1 cells after 72 hrs by MTT assay relative to untreated control, GI50 = 0.9 μM. |
24389510 |
RWPE1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human RWPE1 cells after 72 hrs by MTT assay relative to untreated control, TGI = 4.8 μM. |
24389510 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 4.71 μM. |
24487188 |
HT-29 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 21.45 μM. |
24487188 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 23.9 μM. |
24487188 |
MDA-MB-231 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 24.22 μM. |
24487188 |
ME180 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human ME180 cells after 48 hrs by MTT assay, IC50 = 8.9 μM. |
24487188 |
PC3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human PC3 cells after 48 hrs by MTT assay, IC50 = 14.4 μM. |
24487188 |
DLD1 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human DLD1 cells assessed as inhibition of cell viability after 72 hrs by MTT assay, IC50 = 20 μM. |
24527835 |
HeLa |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human HeLa cells assessed as inhibition of cell viability after 72 hrs by MTT assay, IC50 = 16 μM. |
24527835 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by SRB assay, IC50 = 2.58 μM. |
24553146 |
DU145 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human DU145 cells after 72 hrs by SRB assay, IC50 = 2.03 μM. |
24553146 |
KB |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB cells after 72 hrs by SRB assay, IC50 = 3.88 μM. |
24553146 |
KB |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human KB cells after 72 hrs by methylene blue assay, IC50 = 1.5 μM. |
24657567 |
KB-S15 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human vincristine/paclitaxel-resistant KB-S15 cells overexpressing P-gp170 after 72 hrs by methylene blue assay, IC50 = 3.5 μM. |
24657567 |
KB-VIN10 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human vincristine/paclitaxel-resistant KB-VIN10 cells overexpressing P-gp170 after 72 hrs by methylene blue assay, IC50 = 26.4 μM. |
24657567 |
KB-7d |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human VP16-resistant KB-7d cells overexpressing MRP after 72 hrs by methylene blue assay, IC50 = 46.1 μM. |
24657567 |
A549 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human A549 cells after 48 hrs by MTT assay, IC50 = 2.45 μM. |
24721832 |
ACHN |
Anticancer assay |
|
48 hrs |
Anticancer activity against human ACHN cells after 48 hrs by MTT assay, IC50 = 2.04 μM. |
24721832 |
DU145 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human DU145 cells after 48 hrs by MTT assay, IC50 = 3.17 μM. |
24721832 |
HeLa |
Anticancer assay |
|
48 hrs |
Anticancer activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 2.75 μM. |
24721832 |
HT-29 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 1.47 μM. |
24721832 |
BGC823 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay, IC50 = 30.74 μM. |
24775914 |
HepG2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 15.32 μM. |
24775914 |
HL-7702 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay, IC50 = 24.61 μM. |
24775914 |
H460 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human H460 cells after 72 hrs by MTT assay, IC50 = 0.1 μM. |
24780599 |
HCT116 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 5 μM. |
24780599 |
MCF7 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 1 μM. |
24780599 |
HepG2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 30.16 μM. |
24836071 |
MOLT3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MOLT3 cells after 48 hrs by MTT assay, IC50 = 0.051 μM. |
24836071 |
EPG85-257P |
Antiproliferative assay |
|
5 days |
Antiproliferative activity against human EPG85-257P cells after 5 days by sulforhodamine B assay, IC50 = 0.105 μM. |
24864039 |
EPG85-257RD |
Antiproliferative assay |
|
5 days |
Antiproliferative activity against human EPG85-257RD cells after 5 days by sulforhodamine B assay, IC50 = 6.2 μM. |
24864039 |
EPG85-257RN |
Antiproliferative assay |
|
5 days |
Antiproliferative activity against human EPG85-257RN cells after 5 days by sulforhodamine B assay, IC50 = 1.55 μM. |
24864039 |
EPP85-181P |
Antiproliferative assay |
|
5 days |
Antiproliferative activity against human EPP85-181P cells after 5 days by sulforhodamine B assay, IC50 = 0.58 μM. |
24864039 |
EPP85-181RN |
Antiproliferative assay |
|
5 days |
Antiproliferative activity against human EPP85-181RN cells after 5 days by sulforhodamine B assay, IC50 = 4.5 μM. |
24864039 |
HT-29 |
Antiproliferative assay |
|
5 days |
Antiproliferative activity against human HT-29 cells after 5 days by sulforhodamine B assay, IC50 = 2.3 μM. |
24864039 |
HT-29RD |
Antiproliferative assay |
|
5 days |
Antiproliferative activity against human HT-29RD cells after 5 days by sulforhodamine B assay, IC50 = 26 μM. |
24864039 |
HT-29RN |
Antiproliferative assay |
|
5 days |
Antiproliferative activity against human HT-29RN cells after 5 days by sulforhodamine B assay, IC50 = 35 μM. |
24864039 |
DU145 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human DU145 cells after 2 days, IC50 = 13.85 μM. |
24904965 |
HCT15 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HCT15 cells after 2 days, IC50 = 9.45 μM. |
24904965 |
MCF10A |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human MCF10A cells after 2 days, IC50 = 12.23 μM. |
24904965 |
T47D |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human T47D cells after 2 days, IC50 = 2.57 μM. |
24904965 |
A549 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human A549 cells after 72 hrs by MTT assay, IC50 = 0.1 μM. |
24950030 |
Hs683 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human Hs683 cells after 72 hrs by MTT assay, IC50 = 1 μM. |
24950030 |
MCF7 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human MCF7 cells after 72 hrs by MTT assay, IC50 = 17 μM. |
24950030 |
PC3 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human PC3 cells after 72 hrs by MTT assay, IC50 = 2 μM. |
24950030 |
SK-MEL-28 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human SK-MEL-28 cells after 72 hrs by MTT assay, IC50 = 1 μM. |
24950030 |
U373 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human U373 cells after 72 hrs by MTT assay, IC50 = 7 μM. |
24950030 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.6 μM. |
25014747 |
HepG2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 20.389 μM. |
25019480 |
MOLT3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MOLT3 cells after 48 hrs by MTT assay, IC50 = 0.051 μM. |
25019480 |
HEK293 |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against HEK293 cells after 4 days by CCK-8 assay, IC50 = 1.04 μM. |
25062006 |
DU145 |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human DU145 cells after 4 days by CCK-8 assay, IC50 = 0.001 μM. |
25062006 |
HCT15 |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human HCT15 cells after 4 days by CCK-8 assay, IC50 = 7.74 μM. |
25062006 |
T47D |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human T47D cells after 4 days by CCK-8 assay, IC50 = 8.74 μM. |
25062006 |
Vero |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against african green monkey Vero cells after 48 hrs by MTT assay, LC50 = 28 μM. |
25078313 |
HEK293 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against HEK293 cells after 48 hrs by MTT assay, LC50 = 18 μM. |
25078313 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 6.27 μM. |
25113878 |
K562 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human K562 cells after 48 hrs by MTT assay, IC50 = 3.39 μM. |
25113878 |
HeLa |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay, GI50 = 0.62 μM. |
25131956 |
MCF7 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay, GI50 = 0.25 μM. |
25131956 |
MIAPaCa2 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human MIAPaCa2 cells assessed as growth inhibition after 48 hrs by SRB assay, GI50 = 1.1 μM. |
25131956 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay, IC50 = 13.78 μM. |
25240702 |
HeLa |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HeLa cells after 72 hrs by sulforhodamine B assay, IC50 = 4.36 μM. |
25240702 |
MDA-MB-231 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay, IC50 = 3.67 μM. |
25240702 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 9.3 μM. |
25402632 |
HCT15 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay, IC50 = 4.6 μM. |
25402632 |
HeLa |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 3.4 μM. |
25402632 |
HepG2 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 3.6 μM. |
25402632 |
U373 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human U373 cells after 72 hrs by MTT assay, IC50 = 8.5 μM. |
25402632 |
ZR-7530 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human ZR-7530 cells after 72 hrs by MTT assay, IC50 = 2.5 μM. |
25402632 |
HeLa |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 4.71 μM. |
25453799 |
MCF7 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 23.9 μM. |
25453799 |
ME180 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human ME180 cells after 72 hrs by MTT assay, IC50 = 8.9 μM. |
25453799 |
PC3 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human PC3 cells after 72 hrs by MTT assay, IC50 = 14.4 μM. |
25453799 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 10.12 μM. |
25462233 |
HepG2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 5.48 μM. |
25462233 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by Alamar Blue assay, IC50 = 2.87 μM. |
25466187 |
L6 |
Cytotoxicity assay |
|
71.5 hrs |
Cytotoxicity against rat L6 cells after 71.5 hrs by Presto Blue assay, IC50 = 18.99 μM. |
25466187 |
DU145 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human DU145 cells after 2 days by CCK-8 assay, IC50 = 0.5 μM. |
25481396 |
HCT15 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HCT15 cells after 2 days by CCK-8 assay, IC50 = 1.1 μM. |
25481396 |
HeLa |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HeLa cells after 2 days by CCK-8 assay, IC50 = 1.26 μM. |
25481396 |
MCF7 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human MCF7 cells after 2 days by CCK-8 assay, IC50 = 0.73 μM. |
25481396 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay, IC50 = 0.8 μM. |
25495422 |
HCT116 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HCT116 cells after 72 hrs by sulforhodamine B assay, IC50 = 1.9 μM. |
25495422 |
K562 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human K562 cells after 72 hrs by sulforhodamine B assay, IC50 = 3.1 μM. |
25495422 |
MDA-MB-231 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay, IC50 = 10.6 μM. |
25495422 |
SKHEP1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SKHEP1 cells after 72 hrs by sulforhodamine B assay, IC50 = 1.1 μM. |
25495422 |
SNU638 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SNU638 cells after 72 hrs by sulforhodamine B assay, IC50 = 0.5 μM. |
25495422 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 8.91 μM. |
25599951 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 0.54 μM. |
25599951 |
HL60 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.06 μM. |
25599951 |
K562 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human K562 cells after 48 hrs by MTT assay, IC50 = 1.64 μM. |
25599951 |
A549 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human A549 cells after 48 hrs by MTT assay, IC50 = 3.01 μM. |
25615796 |
DU145 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human DU145 cells after 48 hrs by MTT assay, IC50 = 1.98 μM. |
25615796 |
HeLa |
Anticancer assay |
|
48 hrs |
Anticancer activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 3.23 μM. |
25615796 |
HepG2 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 2.45 μM. |
25615796 |
MCF7 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 2.69 μM. |
25615796 |
HepG2 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 1.4 μM. |
25644672 |
MDA-MB-468 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 6.69 μM. |
25644672 |
THP1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human THP1 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 1.82 μM. |
25644672 |
U937 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 1.1 μM. |
25644672 |
EL4 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against mouse EL4 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 4.9 μM. |
25644672 |
N9 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against mouse N9 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 1.95 μM. |
25644672 |
RAW264.7 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 0.82 μM. |
25644672 |
S17 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against mouse S17 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 10.4 μM. |
25644672 |
A549 |
Antiproliferative assay |
|
3 days |
Antiproliferative activity against human A549 cells after 3 days by sulforhodamine B assay, IC50 = 0.8 μM. |
25700232 |
HCT116 |
Antiproliferative assay |
|
3 days |
Antiproliferative activity against human HCT116 cells after 3 days by sulforhodamine B assay, IC50 = 1.9 μM. |
25700232 |
K562 |
Antiproliferative assay |
|
3 days |
Antiproliferative activity against human K562 cells after 3 days by sulforhodamine B assay, IC50 = 3.1 μM. |
25700232 |
MDA-MB-231 |
Antiproliferative assay |
|
3 days |
Antiproliferative activity against human MDA-MB-231 cells after 3 days by sulforhodamine B assay, IC50 = 11 μM. |
25700232 |
SKHEP1 |
Antiproliferative assay |
|
3 days |
Antiproliferative activity against human SKHEP1 cells after 3 days by sulforhodamine B assay, IC50 = 1.1 μM. |
25700232 |
SNU638 |
Antiproliferative assay |
|
3 days |
Antiproliferative activity against human SNU638 cells after 3 days by sulforhodamine B assay, IC50 = 0.5 μM. |
25700232 |
A549 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human A549 cells after 48 hrs by MTT assay, IC50 = 11.92 μM. |
25744190 |
HL60 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.31 μM. |
25744190 |
MCF7 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 32.82 μM. |
25744190 |
SMMC7721 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human SMMC7721 cells after 48 hrs by MTT assay, IC50 = 8.12 μM. |
25744190 |
SW480 |
Anticancer assay |
|
48 hrs |
Anticancer activity against human SW480 cells after 48 hrs by MTT assay, IC50 = 17.11 μM. |
25744190 |
CCRF-CEM |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human CCRF-CEM cells after 72 hrs by MTT assay, GI50 = 1.6 μM. |
25792142 |
HT-29 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay, GI50 = 31.6 μM. |
25792142 |
MCF7 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, GI50 = 19.9 μM. |
25792142 |
PC3 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human PC3 cells after 72 hrs by MTT assay, GI50 = 0.6 μM. |
25792142 |
PC3 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human PC3 cells after 72 hrs by MTT assay, TGI = 4 μM. |
25792142 |
DU145 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human DU145 cells assessed as cell viability incubated for 72 hrs by MTT assay, IC50 = 0.4 μM. |
25799376 |
PC3 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human PC3 cells assessed as cell viability incubated for 72 hrs by MTT assay, IC50 = 4.33 μM. |
25799376 |
U937 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human U937 cells after 24 hrs by MTT assay, IC50 = 1.5 μM. |
25800433 |
MDA-MB-435 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MDA-MB-435 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 2.81 μM. |
25800514 |
HL60 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by trypan blue staining-based hemocytometric analysis, GI50 = 0.4 μM. |
25874335 |
HBL100 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HBL100 cells after 48 hrs incubation by SRB assay, GI50 = 1.9 μM. |
25899335 |
HeLa |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HeLa cells after 48 hrs incubation by SRB assay, GI50 = 2 μM. |
25899335 |
SW1573 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human SW1573 cells after 48 hrs incubation by SRB assay, GI50 = 3 μM. |
25899335 |
T47D |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human T47D cells after 48 hrs incubation by SRB assay, GI50 = 15 μM. |
25899335 |
WiDr |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human WiDr cells after 48 hrs incubation by SRB assay, GI50 = 26 μM. |
25899335 |
K/VP.5 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against etoposide-resistant human K/VP.5 cells assessed as cell growth inhibition after 72 hrs by MTS assay, IC50 = 2.5 μM. |
25922181 |
K562 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human K562 cells assessed as cell growth inhibition after 72 hrs by MTS assay, IC50 = 0.163 μM. |
25922181 |
DU145 |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human DU145 cells measured on day 4 by CCK8 assay, IC50 = 2.09 μM. |
25936262 |
HCT15 |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human HCT15 cells measured on day 4 by CCK8 assay, IC50 = 18.87 μM. |
25936262 |
HeLa |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human HeLa cells measured on day 4 by CCK8 assay, IC50 = 7.32 μM. |
25936262 |
T47D |
Cytotoxicity assay |
|
4 days |
Cytotoxicity against human T47D cells measured on day 4 by CCK8 assay, IC50 = 13.7 μM. |
25936262 |
NALM6 |
Cytotoxicity assay |
|
5 days |
Cytotoxicity against human NALM6 cells expressing 50% TOP2A assessed as growth inhibition after 5 days by XTT assay, IC50 = 0.234 μM. |
25945730 |
NALM6 |
Cytotoxicity assay |
|
5 days |
Cytotoxicity against TOP2B double knockout human NALM6 cells assessed as growth inhibition after 5 days by XTT assay, IC50 = 0.182 μM. |
25945730 |
NALM6 |
Cytotoxicity assay |
|
5 days |
Cytotoxicity against wild type human NALM6 cells assessed as growth inhibition after 5 days by XTT assay, IC50 = 0.134 μM. |
25945730 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by sulforhodamine B assay, IC50 = 0.4 μM. |
26010585 |
HCT116 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 72 hrs by sulforhodamine B assay, IC50 = 1.9 μM. |
26010585 |
MDA-MB-231 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell proliferation after 72 hrs by sulforhodamine B assay, IC50 = 7.7 μM. |
26010585 |
SKHEP1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SKHEP1 cells assessed as inhibition of cell proliferation after 72 hrs by sulforhodamine B assay, IC50 = 2.8 μM. |
26010585 |
SNU638 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SNU638 cells assessed as inhibition of cell proliferation after 72 hrs by sulforhodamine B assay, IC50 = 0.3 μM. |
26010585 |
DU145 |
Cytotoxicity assay |
|
2 to 4 days |
Cytotoxicity against human DU145 cells incubated from day 2 to day 4 by CCK8 assay, IC50 = 0.5 μM. |
26022080 |
HCT15 |
Cytotoxicity assay |
|
2 to 4 days |
Cytotoxicity against human HCT15 cells incubated from day 2 to day 4 by CCK8 assay, IC50 = 1.1 μM. |
26022080 |
HeLa |
Cytotoxicity assay |
|
2 to 4 days |
Cytotoxicity against human HeLa cells incubated from day 2 to day 4 by CCK8 assay, IC50 = 1.41 μM. |
26022080 |
T47D |
Cytotoxicity assay |
|
2 to 4 days |
Cytotoxicity against human T47D cells incubated from day 2 to day 4 by CCK8 assay, IC50 = 0.7 μM. |
26022080 |
KB |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human KB cells after 72 hrs by methylene blue assay, IC50 = 1.5 μM. |
26160020 |
KB-7d |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human KB-7d cells expressing MRP after 72 hrs by methylene blue assay, IC50 = 46.1 μM. |
26160020 |
KB-S15 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human KB-S15 cells expressing P-gp170/MDR after 72 hrs by methylene blue assay, IC50 = 3.5 μM. |
26160020 |
KB-VIN10 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human KB-VIN10 cells expressing P-gp170/MDR after 72 hrs by methylene blue assay, IC50 = 26.4 μM. |
26160020 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by Hoechst assay, IC50 = 0.48 μM. |
26225905 |
DLD1 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human DLD1 cells assessed as inhibition of cell growth incubated for 48 hrs by Hoechst assay, IC50 = 3.3 μM. |
26225905 |
HepG2 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HepG2 cells after 72 hrs by SRB assay, IC50 = 30 μM. |
26291037 |
MDA-MB-231 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by SRB assay, IC50 = 3.6 μM. |
26291037 |
MDA-MB-435 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human MDA-MB-435 cells after 72 hrs by SRB assay, IC50 = 1.7 μM. |
26291037 |
PC3 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human PC3 cells after 72 hrs by SRB assay, IC50 = 1 μM. |
26291037 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 38.5 μM. |
26292628 |
DU145 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human DU145 cells after 48 hrs by MTT assay, IC50 = 5.21 μM. |
26292628 |
HGC |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HGC cells after 48 hrs by MTT assay, IC50 = 10.9 μM. |
26292628 |
MDA-MB-231 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 49.35 μM. |
26292628 |
RWPE1 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human RWPE1 cells after 48 hrs by MTT assay, IC50 = 27.64 μM. |
26292628 |
HCT15 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HCT15 cells measured after 2 days by MTT assay, IC50 = 5.54 μM. |
26334499 |
HeLa |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HeLa cells measured after 2 days by MTT assay, IC50 = 7.6 μM. |
26334499 |
T47D |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human T47D cells measured after 2 days by MTT assay, IC50 = 9.28 μM. |
26334499 |
GBM2 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human GBM2 cells assessed as reduction in cell viability incubated for 72 hrs by WST-1 method, IC50 = 1.1 μM. |
26355532 |
DU145 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human DU145 cells after 2 days by CCK8 assay, IC50 = 13.1 μM. |
26361737 |
HCT15 |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human HCT15 cells after 2 days by CCK8 assay, IC50 = 2.6 μM. |
26361737 |
MCF10A |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human MCF10A cells after 2 days by CCK8 assay, IC50 = 10.14 μM. |
26361737 |
T47D |
Cytotoxicity assay |
|
2 days |
Cytotoxicity against human T47D cells after 2 days by CCK8 assay, IC50 = 0.94 μM. |
26361737 |
HepG2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 33.98 μM. |
26397393 |
MOLT3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MOLT3 cells after 48 hrs by XTT assay, IC50 = 0.041 μM. |
26397393 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by resazurin assay, IC50 = 1.7 μM. |
26592897 |
DLD1 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human DLD1 cells assessed as growth inhibition after 48 hrs by resazurin assay, IC50 = 2 μM. |
26592897 |
A549 |
Antiproliferative assay |
|
24 to 72 hrs |
Antiproliferative activity against human A549 cells after 24 to 72 hrs by SRB assay, IC50 = 0.8 μM. |
26595875 |
CAKI-1 |
Antiproliferative assay |
|
24 to 72 hrs |
Antiproliferative activity against human CAKI-1 cells after 24 to 72 hrs by SRB assay, IC50 = 1.1 μM. |
26595875 |
HCT116 |
Antiproliferative assay |
|
24 to 72 hrs |
Antiproliferative activity against human HCT116 cells after 24 to 72 hrs by SRB assay, IC50 = 3.3 μM. |
26595875 |
HCT116 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HCT116 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 2.3 μM. |
26595875 |
HCT116 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by SRB assay, IC50 = 0.3 μM. |
26595875 |
K562 |
Antiproliferative assay |
|
24 to 72 hrs |
Antiproliferative activity against human K562 cells after 24 to 72 hrs by SRB assay, IC50 = 6.7 μM. |
26595875 |
HCT116 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against p53-expressing human HCT116 cells assessed as cell viability after 72 hrs by SRB assay, IC50 = 1.1 μM. |
26595875 |
HCT116 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against p53-null human HCT116 cells assessed as cell viability after 72 hrs by SRB assay, IC50 = 3.1 μM. |
26595875 |
A549 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human A549 cells assessed as growth inhibition after 72 hrs by CCK-8 assay, IC50 = 2.675 μM. |
26615886 |
HeLa |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HeLa cells assessed as growth inhibition after 72 hrs by CCK-8 assay, IC50 = 1.605 μM. |
26615886 |
HepG2 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HepG2 cells assessed as growth inhibition after 72 hrs by CCK-8 assay, IC50 = 1.748 μM. |
26615886 |
K562 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human K562 cells assessed as growth inhibition after 72 hrs by CCK-8 assay, IC50 = 0.413 μM. |
26615886 |
K562/ADR |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human K562/ADR cells assessed as growth inhibition after 72 hrs by CCK-8 assay, IC50 = 2.025 μM. |
26615886 |
HCT116 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by SRB assay, IC50 = 26.1 μM. |
26618211 |
HeLa |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HeLa cells assessed as cell viability after 72 hrs by SRB assay, IC50 = 3.2 μM. |
26618211 |
MDA-MB-231 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human MDA-MB-231 cells assessed as cell viability after 72 hrs by SRB assay, IC50 = 4.2 μM. |
26618211 |
A549 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 6.74 μM. |
26649766 |
HeLa |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 32.45 μM. |
26649766 |
HL60 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.16 μM. |
26649766 |
HL60/MX2 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HL60/MX2 cells after 48 hrs by MTT assay, IC50 = 9.02 μM. |
26649766 |
K562 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay, IC50 = 0.51 μM. |
26649766 |
MDA-MB-201 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human MDA-MB-201 cells after 48 hrs by MTT assay, IC50 = 31.33 μM. |
26649766 |
Raji |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human Raji cells after 48 hrs by MTT assay, IC50 = 1.68 μM. |
26649766 |
HEK293 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against HEK293 cells after 48 hrs by MTT assay, IC50 = 0.69 μM. |
26649766 |
GM07492A |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human GM07492A cells assessed as cell growth inhibition after 24 hrs by XTT assay, IC50 = 1.2 μM. |
26649907 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by SRB assay, IC50 = 1.74 μM. |
26706168 |
HCT15 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HCT15 cells after 48 hrs by SRB assay, IC50 = 2.95 μM. |
26706168 |
SK-MEL-2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay, IC50 = 1.33 μM. |
26706168 |
SKOV3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay, IC50 = 1.96 μM. |
26706168 |
HT-29 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HT-29 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay, IC50 = 2.2 μM. |
26731300 |
MCF7 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human MCF7 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay, IC50 = 0.8 μM. |
26731300 |
PC3 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human PC3 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay, IC50 = 1.1 μM. |
26731300 |
T84 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human T84 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay, IC50 = 3 μM. |
26731300 |
A375 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A375 cells assessed as growth inhibition after 72 hrs by ATPlite assay, IC50 = 0.24 μM. |
26793989 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by ATPlite assay, IC50 = 0.59 μM. |
26793989 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60 cells assessed as growth inhibition after 72 hrs by ATPlite assay, IC50 = 0.86 μM. |
26793989 |
HCT116 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 1.7 μM. |
26804229 |
HepG2 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 5.62 μM. |
26804229 |
22Rv1 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human 22Rv1 cells after 96 hrs by propidium iodide-based monolayer assay, IC50 = 0.364 μM. |
26854430 |
MCF7 |
Antiproliferative assay |
|
96 hrs |
Antiproliferative activity against human MCF7 cells after 96 hrs by propidium iodide-based monolayer assay, IC50 = 1.264 μM. |
26854430 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 23.94 μM. |
26873416 |
HCT8 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HCT8 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 10.89 μM. |
26873416 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 12.12 μM. |
26873416 |
HepG2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 27.07 μM. |
26873416 |
WI38 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human WI38 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 35.8 μM. |
26873416 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 12.4 μM. |
26890115 |
MDA-MB-231 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 15.7 μM. |
26890115 |
T47D |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human T47D cells after 48 hrs by MTT assay, IC50 = 11.8 μM. |
26890115 |
K562 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human K562 cells assessed as reduction in viable cells after 48 hrs by MTT assay, IC50 = 4.39 μM. |
26916436 |
HONE1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HONE1 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 1.2 μM. |
26920801 |
HT-29 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 2 μM. |
26920801 |
MCF7 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 2.2 μM. |
26920801 |
P388 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against mouse P388 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 1.3 μM. |
26920801 |
HCT15 |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human HCT15 cells after 3 days by CCK8 assay, IC50 = 2.82 μM. |
26927425 |
HeLa |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human HeLa cells after 3 days by CCK8 assay, IC50 = 0.18 μM. |
26927425 |
T47D |
Cytotoxicity assay |
|
3 days |
Cytotoxicity against human T47D cells after 3 days by CCK8 assay, IC50 = 1.84 μM. |
26927425 |
DU145 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human DU145 cells after 48 hrs by CCK8 assay, IC50 = 2.09 μM. |
26945111 |
HCT15 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HCT15 cells after 48 hrs by CCK8 assay, IC50 = 18.87 μM. |
26945111 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells after 48 hrs by CCK8 assay, IC50 = 7.32 μM. |
26945111 |
T47D |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human T47D cells after 48 hrs by CCK8 assay, IC50 = 13.7 μM. |
26945111 |
BT474 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human BT474 cells after 72 hrs by CCK8 assay, IC50 = 6.6 μM. |
26988802 |
HCT15 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay, IC50 = 6.9 μM. |
26988802 |
T47D |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay, IC50 = 6.4 μM. |
26988802 |
A549 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 3.82 μM. |
27060757 |
CCRF-CEM |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human CCRF-CEM cells after 48 hrs by MTT assay, IC50 = 0.12 μM. |
27060757 |
HCT116 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 6.03 μM. |
27060757 |
HeLa |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 41.21 μM. |
27060757 |
A375 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human A375 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay, IC50 = 0.24 μM. |
27096049 |
A549 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay, IC50 = 0.59 μM. |
27096049 |
HL60 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HL60 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay, IC50 = 0.86 μM. |
27096049 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 0.5 μM. |
27145162 |
MOLT3 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MOLT3 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 0.7 μM. |
27145162 |
HEK293T |
Cytotoxicity assay |
|
36 hrs |
Cytotoxicity against HEK293T cells after 36 hrs by MTT assay, IC50 = 11.47 μM. |
27262599 |
A549 |
Cytotoxicity assay |
|
36 hrs |
Cytotoxicity against human A549 cells after 36 hrs by MTT assay, IC50 = 8.01 μM. |
27262599 |
HeLa |
Cytotoxicity assay |
|
36 hrs |
Cytotoxicity against human HeLa cells after 36 hrs by MTT assay, IC50 = 4.39 μM. |
27262599 |
MCF7 |
Cytotoxicity assay |
|
36 hrs |
Cytotoxicity against human MCF7 cells after 36 hrs by MTT assay, IC50 = 1.74 μM. |
27262599 |
HEK293 |
Anticlonogenic assay |
|
48 hrs |
Anticlonogenic activity against HEK293 cells assessed as inhibition of colony formation incubated for 48 hrs measured after 6 days by crystal violet staining based assay, LC50 = 20 μM. |
27343852 |
HEK293 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by MTT assay, LC50 = 22 μM. |
27343852 |
H460 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human H460 cells after 72 hrs by MTT assay, IC50 = 0.1 μM. |
27448912 |
HCT116 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 5 μM. |
27448912 |
MCF7 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 1 μM. |
27448912 |
shGFP-fused HMLE |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human shGFP-fused HMLE cells after 72 hrs by MTT assay, IC50 = 0.4 μM. |
27448912 |
HCT15 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HCT15 cells assessed as reduction in cell growth after 72 hrs by CCK8 assay, IC50 = 1.06 μM. |
27484510 |
HeLa |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HeLa cells assessed as reduction in cell growth after 72 hrs by CCK8 assay, IC50 = 10.03 μM. |
27484510 |
NCI-N87 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human NCI-N87 cells assessed as reduction in cell growth after 72 hrs by CCK8 assay, IC50 = 1.29 μM. |
27484510 |
T47D |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human T47D cells assessed as reduction in cell growth after 72 hrs by CCK8 assay, IC50 = 2.8 μM. |
27484510 |
K562 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human K562 cells measured after 72 hrs by CCK8 assay, IC50 = 0.345 μM. |
27484511 |
K562/ADR |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human K562/ADR cells measured after 72 hrs by CCK8 assay, IC50 = 2.211 μM. |
27484511 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells measured after 48 hrs by MTT assay, IC50 = 29.7 μM. |
27517805 |
HCT8 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HCT8 cells measured after 48 hrs by MTT assay, IC50 = 10 μM. |
27517805 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells measured after 48 hrs by MTT assay, IC50 = 13.5 μM. |
27517805 |
HepG2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HepG2 cells measured after 48 hrs by MTT assay, IC50 = 5.21 μM. |
27517805 |
WI38 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human WI38 cells measured after 48 hrs by MTT assay, IC50 = 17.6 μM. |
27517805 |
HEK293 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50 = 0.6 μM. |
27533261 |
H1975-1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human H1975-1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay, IC50 = 9.5 μM. |
27560280 |
HeLa |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay, IC50 = 8.2 μM. |
27560280 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay, IC50 = 2.1 μM. |
27560280 |
Vero |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay, IC50 = 1.5 μM. |
27560280 |
HCT116 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against resistant human HCT116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay, IC50 = 2.8 μM. |
27560280 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 0.3 μM. |
27598828 |
HEK293 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against HEK293 cells after 72 hrs by CCK8 assay, IC50 = 1.74 μM. |
27643560 |
DU145 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human DU145 cells after 72 hrs by CCK8 assay, IC50 = 0.02 μM. |
27643560 |
HCT15 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay, IC50 = 1.1 μM. |
27643560 |
HeLa |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay, IC50 = 0.18 μM. |
27643560 |
T47D |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay, IC50 = 1.84 μM. |
27643560 |
DU145 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human DU145 cells measured after 72 hrs by CCK8 assay, IC50 = 2.19 μM. |
27654394 |
HCT15 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HCT15 cells measured after 72 hrs by CCK8 assay, IC50 = 1.27 μM. |
27654394 |
MCF7 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human MCF7 cells measured after 72 hrs by CCK8 assay, IC50 = 35.55 μM. |
27654394 |
T47D |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human T47D cells measured after 72 hrs by CCK8 assay, IC50 = 4.85 μM. |
27654394 |
HBL100 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HBL100 cells assessed as growth inhibition after 48 hrs by SRB assay, GI50 = 1.4 μM. |
27765506 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay, GI50 = 3.3 μM. |
27765506 |
SW1573 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SW1573 cells assessed as growth inhibition after 48 hrs by SRB assay, GI50 = 15 μM. |
27765506 |
WiDr |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human WiDr cells assessed as growth inhibition after 48 hrs by SRB assay, GI50 = 23 μM. |
27765506 |
MCF7 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 27.41 μM. |
27863370 |
MDA-MB-231 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 13.35 μM. |
27863370 |
T47D |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human T47D cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 9.8 μM. |
27863370 |
HEK293T |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against HEK293T cells assessed as cells growth inhibition after 48 hrs by MTT assay, IC50 = 22 μM. |
27994737 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by SRB assay, GI50 = 0.56 μM. |
28041801 |
TK10 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human TK10 cells assessed as cell growth inhibition after 48 hrs by SRB assay, GI50 = 7.19 μM. |
28041801 |
TK10 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human TK10 cells assessed as cell growth inhibition after 48 hrs by SRB assay, TGI = 49.74 μM. |
28041801 |
UACC62 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human UACC62 cells assessed as cell growth inhibition after 48 hrs by SRB assay, GI50 = 0.89 μM. |
28041801 |
THP1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human THP1 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 1.82 μM. |
28062194 |
U937 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 1.1 μM. |
28062194 |
EL4 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against mouse EL4 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 4.9 μM. |
28062194 |
S17 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against mouse S17 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 10.4 μM. |
28062194 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 5.87 μM. |
28068602 |
DU145 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 3.1 μM. |
28068602 |
MDA-MB-231 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 20.3 μM. |
28068602 |
PC3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 13.9 μM. |
28068602 |
HCT15 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay, IC50 = 5.4 μM. |
28068603 |
HeLa |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay, IC50 = 9.1 μM. |
28068603 |
T47D |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay, IC50 = 7 μM. |
28068603 |
HepG2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by Cell Titer-Glo assay, EC50 = 15.9 μM. |
28080063 |
HEK293 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against HEK293 cells after 48 hrs by SRB assay, IC50 = 7.51 μM. |
28094224 |
DLD1 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human DLD1 cells after 48 hrs by SRB assay, IC50 = 8.11 μM. |
28094224 |
DU145 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human DU145 cells after 48 hrs by SRB assay, IC50 = 10.64 μM. |
28094224 |
FADU |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human FADU cells after 48 hrs by SRB assay, IC50 = 16.01 μM. |
28094224 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by SRB assay, IC50 = 0.92 μM. |
28165740 |
BT549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human BT549 cells after 48 hrs by SRB assay, IC50 = 1.24 μM. |
28165740 |
SK-MEL-2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay, IC50 = 1.1 μM. |
28165740 |
SKOV3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay, IC50 = 1.95 μM. |
28165740 |
HepG2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 0.83 μM. |
28169166 |
LO2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 3.78 μM. |
28169166 |
SMMC7721 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 0.15 μM. |
28169166 |
HCT15 |
Antiproliferative assay |
|
24 hrs |
Antiproliferative activity against human HCT15 cells after 24 hrs by WST-1 assay, IC50 = 19.7 μM. |
28181805 |
HeLaS3 |
Antiproliferative assay |
|
24 hrs |
Antiproliferative activity against human HeLaS3 cells after 24 hrs by WST-1 assay, IC50 = 43.1 μM. |
28181805 |
HCT15 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay, IC50 = 1.33 μM. |
28384547 |
HeLa |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay, IC50 = 3.2 μM. |
28384547 |
T47D |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay, IC50 = 3.25 μM. |
28384547 |
Vero |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against African green monkey Vero cells assessed as decrease in cell viability after 72 hrs by MTT assay, IC50 = 16 μM. |
28385594 |
HCT116 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 72 hrs by MTT assay, IC50 = 3 μM. |
28385594 |
HeLa |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by MTT assay, IC50 = 8 μM. |
28385594 |
HL60 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HL60 cells assessed as decrease in cell viability after 72 hrs by MTT assay, IC50 = 20 μM. |
28385594 |
K562 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human K562 cells assessed as decrease in cell viability after 72 hrs by MTT assay, IC50 = 12 μM. |
28385594 |
A549 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human A549 cells after 72 hrs by MTT assay, GI50 = 1.7 μM. |
28406636 |
Hs683 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human Hs683 cells after 72 hrs by MTT assay, GI50 = 1.5 μM. |
28406636 |
MCF7 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human MCF7 cells after 72 hrs by MTT assay, GI50 = 4 μM. |
28406636 |
SK-MEL-28 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human SK-MEL-28 cells after 72 hrs by MTT assay, GI50 = 3.2 μM. |
28406636 |
U373 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human U373 cells after 72 hrs by MTT assay, GI50 = 24.9 μM. |
28406636 |
HeLa |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 7.89 μM. |
28431878 |
MDA-MB-231 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay, IC50 = 29.27 μM. |
28431878 |
SMMC7721 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay, IC50 = 40.44 μM. |
28431878 |
A549 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 19.83 μM. |
28462840 |
HeLa |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 15.93 μM. |
28462840 |
MCF7 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 24.01 μM. |
28462840 |
MGC803 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 20.91 μM. |
28462840 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 14.7 μM. |
28512026 |
HCT8 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HCT8 cells after 48 hrs by MTT assay, IC50 = 26.3 μM. |
28512026 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 24.9 μM. |
28512026 |
HepG2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 13.4 μM. |
28512026 |
WI38 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human WI38 cells after 48 hrs by MTT assay, IC50 = 46.9 μM. |
28512026 |
A549 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human A549 cells incubated for 72 hrs by sulforhodamine B assay, IC50 = 0.3 μM. |
28625715 |
HCT116 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human HCT116 cells incubated for 72 hrs by sulforhodamine B assay, IC50 = 1.06 μM. |
28625715 |
K562 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human K562 cells incubated for 72 hrs by sulforhodamine B assay, IC50 = 0.76 μM. |
28625715 |
MDA-MB-231 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human MDA-MB-231 cells incubated for 72 hrs by sulforhodamine B assay, IC50 = 1.53 μM. |
28625715 |
MRC5 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human MRC5 cells incubated for 72 hrs by sulforhodamine B assay, IC50 = 11.73 μM. |
28625715 |
SKHEP1 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human SKHEP1 cells incubated for 72 hrs by sulforhodamine B assay, IC50 = 0.63 μM. |
28625715 |
SNU638 |
Growth inhibition assay |
|
72 hrs |
Growth inhibition of human SNU638 cells incubated for 72 hrs by sulforhodamine B assay, IC50 = 1.05 μM. |
28625715 |
HCT15 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay, IC50 = 9.27 μM. |
28633898 |
HeLa |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay, IC50 = 4.12 μM. |
28633898 |
T47D |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay, IC50 = 8.81 μM. |
28633898 |
HeLa |
Cytotoxicity assay |
|
72 hrs |
Cytotoxic activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 7.21 μM. |
28733083 |
MDA-MB-231 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxic activity against human MDA-MB-231 cells after 72 hrs by MTT assay, IC50 = 16.27 μM. |
28733083 |
SMMC7721 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxic activity against human SMMC7721 cells after 72 hrs by MTT assay, IC50 = 21.03 μM. |
28733083 |
A549 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human A549 cells after 24 hrs by MTT assay, IC50 = 6.21 μM. |
28757065 |
HeLa |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human HeLa cells after 24 hrs by MTT assay, IC50 = 1.58 μM. |
28757065 |
HepG2 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay, IC50 = 5.52 μM. |
28757065 |
L02 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human L02 cells after 24 hrs by MTT assay, IC50 = 7.75 μM. |
28757065 |
MCF7 |
Cytotoxicity assay |
|
24 hrs |
Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay, IC50 = 2.08 μM. |
28757065 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by SRB assay, IC50 = 1.1 μM. |
28841320 |
BT549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human BT549 cells after 48 hrs by SRB assay, IC50 = 1 μM. |
28841320 |
SK-MEL-2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay, IC50 = 0.2 μM. |
28841320 |
SKOV3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay, IC50 = 2.9 μM. |
28841320 |
SK-MEL-1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SK-MEL-1 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 8 μM. |
29032930 |
A549 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 1.3 μM. |
29077404 |
DU145 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human DU145 cells after 72 hrs by MTT assay, IC50 = 1 μM. |
29077404 |
HeLa |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 2.4 μM. |
29077404 |
MCF7 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 10.5 μM. |
29077404 |
A549 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human A549 cells after 48 hrs by SRB assay, GI50 = 1.5 μM. |
29129514 |
HBL100 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay, GI50 = 2.3 μM. |
29129514 |
HeLa |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay, GI50 = 3 μM. |
29129514 |
SW1573 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay, GI50 = 15 μM. |
29129514 |
T47D |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human T47D cells after 48 hrs by SRB assay, GI50 = 22 μM. |
29129514 |
WiDr |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay, GI50 = 23 μM. |
29129514 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells assessed as reduction in inhibition of cell growth incubated for 48 hrs by MTT assay, IC50 = 9.1 μM. |
29248296 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells assessed as reduction in inhibition of cell growth incubated for 48 hrs by MTT assay, IC50 = 11.2 μM. |
29248296 |
HepG2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HepG2 cells assessed as reduction in inhibition of cell growth incubated for 48 hrs by MTT assay, IC50 = 9.2 μM. |
29248296 |
LoVo |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human LoVo cells assessed as reduction in inhibition of cell growth incubated for 48 hrs by MTT assay, IC50 = 18.7 μM. |
29248296 |
WI38 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human WI38 cells assessed as reduction in inhibition of cell growth incubated for 48 hrs by MTT assay, IC50 = 25.7 μM. |
29248296 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 2.03 μM. |
29269253 |
DU145 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human DU145 cells after 48 hrs by MTT assay, IC50 = 2.03 μM. |
29269253 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 2.03 μM. |
29269253 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 2.03 μM. |
29269253 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 2.27 μM. |
29289881 |
DU145 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human DU145 cells after 48 hrs by MTT assay, IC50 = 1.97 μM. |
29289881 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 1.93 μM. |
29289881 |
HT-29 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 1.64 μM. |
29289881 |
MDA-MB-231 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 1.91 μM. |
29289881 |
A549 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 1.97 μM. |
29289884 |
DU145 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay, IC50 = 2.35 μM. |
29289884 |
HeLa |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 2.71 μM. |
29289884 |
HepG2 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 2.84 μM. |
29289884 |
HT-29 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 1.87 μM. |
29289884 |
MCF7 |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 1.62 μM. |
29289884 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 32.61 μM. |
29335211 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 22.35 μM. |
29335211 |
HL60 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 0.19 μM. |
29335211 |
PC3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 5.73 μM. |
29335211 |
HCT15 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HCT15 cells incubated for 72 hrs by CCK8 assay, IC50 = 2.94 μM. |
29402741 |
HeLa |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HeLa cells incubated for 72 hrs by CCK8 assay, IC50 = 9.21 μM. |
29402741 |
T47D |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human T47D cells incubated for 72 hrs by CCK8 assay, IC50 = 0.4 μM. |
29402741 |
HCT15 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HCT15 cells after 72 hrs by CCK-8 assay, IC50 = 2.45 μM. |
29510948 |
HeLa |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HeLa cells after 72 hrs by CCK-8 assay, IC50 = 10.03 μM. |
29510948 |
T47D |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human T47D cells after 72 hrs by CCK-8 assay, IC50 = 0.32 μM. |
29510948 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 3.25 μM. |
29525336 |
DU145 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 2.13 μM. |
29525336 |
HCT116 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 2.6 μM. |
29525336 |
HT-29 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HT-29 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 1.8 μM. |
29525336 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 2.03 μM. |
29525336 |
PC3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 5.4 μM. |
29525336 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 13.71 μM. |
29545100 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 32.05 μM. |
29545100 |
HL60 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.33 μM. |
29545100 |
K562 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human K562 cells after 48 hrs by MTT assay, IC50 = 8.45 μM. |
29545100 |
K562 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human etoposide-sensitive K562 cells after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay, IC50 = 1.22 μM. |
29656990 |
HT-29 |
Cytotoxicity assay |
|
24 to 72 hrs |
Cytotoxicity against human HT-29 cells measured after 24 to 72 hrs by SRB assay, IC50 = 15 μM. |
29656990 |
K/VP.5 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human K/VP.5 cells after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay, IC50 = 35.36 μM. |
29656990 |
OVCAR3 |
Cytotoxicity assay |
|
24 to 72 hrs |
Cytotoxicity against human OVCAR3 cells measured after 24 to 72 hrs by SRB assay, IC50 = 2.9 μM. |
29656990 |
CCRF-CEM |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human CCRF-CEM cells assessed as growth inhibition after 72 hrs by MTT assay, GI50 = 1.26 μM. |
29670691 |
HT-29 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by MTT assay, GI50 = 31.62 μM. |
29670691 |
K562 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human K562 cells assessed as growth inhibition after 72 hrs by MTT assay, GI50 = 12.59 μM. |
29670691 |
MCF7 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay, GI50 = 19.95 μM. |
29670691 |
PC3 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay, GI50 = 0.63 μM. |
29670691 |
K562 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human K562 cells after 72 hrs by CCK8 assay, IC50 = 0.764 μM. |
29678463 |
K562/VCR |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human K562/VCR cells after 72 hrs by CCK8 assay, IC50 = 11.84 μM. |
29678463 |
HepG2 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HepG2 cells assessed as reduction in cell proliferation after 72 hrs by MTS assay, IC50 = 20.1 μM. |
29778894 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 9.4695 μM. |
29886322 |
L02 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human L02 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 3.4805 μM. |
29886322 |
MCF7 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 4.7165 μM. |
29886322 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay, IC50 = 0.72 μM. |
29893558 |
HCT116 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HCT116 cells after 72 hrs by sulforhodamine B assay, IC50 = 0.68 μM. |
29893558 |
K562 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human K562 cells after 72 hrs by sulforhodamine B assay, IC50 = 1.3 μM. |
29893558 |
MDA-MB-231 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay, IC50 = 4.4 μM. |
29893558 |
SKHEP1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SKHEP1 cells after 72 hrs by sulforhodamine B assay, IC50 = 0.93 μM. |
29893558 |
SNU638 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SNU638 cells after 72 hrs by sulforhodamine B assay, IC50 = 0.43 μM. |
29893558 |
A549 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 0.3 μM. |
30041947 |
HCT116 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 1.06 μM. |
30041947 |
K562 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human K562 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 0.76 μM. |
30041947 |
MDA-MB-231 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 1.53 μM. |
30041947 |
MRC5 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human MRC5 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 11.73 μM. |
30041947 |
SKHEP1 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SKHEP1 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 0.63 μM. |
30041947 |
SNU638 |
Cytotoxicity assay |
|
72 hrs |
Cytotoxicity against human SNU638 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 1.05 μM. |
30041947 |
CCRF-CEM |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human CCRF-CEM cells after 72 hrs by MTT assay, GI50 = 1.6 μM. |
30071406 |
HT-29 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay, GI50 = 31.6 μM. |
30071406 |
MCF7 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, GI50 = 19.9 μM. |
30071406 |
PC3 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, GI50 = 0.6 μM. |
30071406 |
PC3 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, TGI = 4 μM. |
30071406 |
HCT15 |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HCT15 cells after 72 hrs by EZ-CYTOX reagent based assay, IC50 = 2.94 μM. |
30262132 |
HeLa |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human HeLa cells after 72 hrs by EZ-CYTOX reagent based assay, IC50 = 9.21 μM. |
30262132 |
T47D |
Antiproliferative assay |
|
72 hrs |
Antiproliferative activity against human T47D cells after 72 hrs by EZ-CYTOX reagent based assay, IC50 = 0.4 μM. |
30262132 |
A549 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 22.5 μM. |
30265994 |
HeLa |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 21.4 μM. |
30265994 |
HepG2 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 20 μM. |
30265994 |
HL7702 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HL7702 cells after 48 hrs by MTT assay, IC50 = 24.6 μM. |
30265994 |
MRC5 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MRC5 cells after 48 hrs by MTT assay, IC50 = 33.5 μM. |
30265994 |
MOLT-3 |
Growth Inhibition Assay |
|
|
IC50=0.051 ± 0.002 μM |
25078311 |
HepG2 |
Growth Inhibition Assay |
|
|
IC50=30.16 ± 0.50 μM |
25078311 |
T47D |
Growth Inhibition Assay |
|
|
IC50=3.18 ± 0.11 μM |
25603122 |
HCT15 |
Growth Inhibition Assay |
|
|
IC50=0.81 ± 0.01 μM |
25603122 |
DU145 |
Growth Inhibition Assay |
|
|
IC50=2.28 ± 0.04 μM |
25603122 |
HEK293 |
Growth Inhibition Assay |
|
|
IC50=7.14 ± 0.36 μM |
25603122 |
SK-N-ASCis24 |
Growth Inhibition Assay |
|
|
IC50=0.57 ± 0.11 μM |
25960282 |
SK-N-AS |
Growth Inhibition Assay |
|
|
IC50=0.24 ± 0.03 μM |
25960282 |
KellyCis83 |
Growth Inhibition Assay |
|
|
IC50=0.16 ± 0.02 μM |
25960282 |
Kelly |
Growth Inhibition Assay |
|
|
IC50=0.12 ± 0.01 μM |
25960282 |
MIAPACA |
Growth Inhibition Assay |
|
|
GI50=1.3 ± 0.03 μM |
24953821 |
MCF-7 |
Growth Inhibition Assay |
|
|
GI50=0.25 ± 0.1 μM |
24953821 |
HeLa |
Growth Inhibition Assay |
|
|
GI50=0.64 ± 0.4 μM |
24953821 |
HCT116 |
Cytotoxicity assay |
|
|
Cytotoxicity against HCT116 cells., IC50 = 2.5 μM. |
7473578 |
CCRF CEM |
Function assay |
|
|
Tested for the inhibitory activity against CCRF CEM T- cell leukemia cells, IC50 = 0.002 μM. |
7932571 |
KB ATCC |
Function assay |
|
|
50% reduction in the number of KB ATCC cells, ID50 = 0.32 μM. |
8120864 |
SCLC |
Cytotoxicity assay |
|
|
Cytotoxicity against human SCLC cells resistant to cisplatin (SCLC/CDDP), IC50 = 1.3 μM. |
8258835 |
HeLa |
Function assay |
|
|
Tested for inhibition of topoisomerase II isolated from HeLa cells by DNA-cleavage assay, EC50 = 0.81 μM. |
8410993 |
KB |
Growth inhibition assay |
|
|
Compound concentration required to reduce the exponential growth of KB cells by 50%, CC50 = 0.1 μM. |
9767632 |
MT-4 |
Growth inhibition assay |
|
|
Compound concentration required to reduce the exponential growth of MT-4 cells by 50%, CC50 = 0.08 μM. |
9767632 |
L1210 |
Cytotoxicity assay |
|
|
In vitro cytotoxic activity against murine L1210 leukemia cells., IC50 = 0.2 μM. |
9804687 |
HL-60 |
Cytotoxicity assay |
|
|
Relative cytotoxicity against human promyelocytic leukemia(HL-60) cells, IC50 = 0.367 μM. |
10377219 |
HL-60 |
Cytotoxicity assay |
|
|
Relative cytotoxicity against human promyelocytic leukemia(HL-60) cells, IC90 = 0.73 μM. |
10377219 |
A549 |
Function assay |
|
|
GI values against A549 cells (lung cancer), GI50 = 6.30957 μM. |
11311065 |
CAKI-1 |
Function assay |
|
|
GI values against CAKI-1 cells(renal carcinoma), GI50 = 6.30957 μM. |
11311065 |
KB |
Function assay |
|
|
GI values against KB cells (nasopharyngeal carcinoma), GI50 = 0.19953 μM. |
11311065 |
HEL |
Function assay |
|
|
Inhibitory activity against human cytomegalovirus (HCMV) in HEL cells, ED50 = 8.64 μM. |
11311065 |
A549 |
Cytotoxicity assay |
|
|
Cytotoxicity against human A549 cells by MTT assay, IC50 = 0.5 μM. |
11473438 |
HL60 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HL60 cells by MTT assay, IC50 = 5.4 μM. |
11473438 |
MCF7 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MCF7 cells by MTT assay, IC50 = 12.3 μM. |
11473438 |
P388 |
Cytotoxicity assay |
|
|
Cytotoxicity against mouse P388 cells by MTT assay, IC50 = 0.1 μM. |
11473438 |
HT-29 |
Cytotoxicity assay |
|
|
Tested for cytotoxicity against Colon carcinoma type HT-29 cell line expressing MDR-1 (-) gene; 35% of cells were affected, IC50 = 10 μM. |
11844671 |
KB |
Function assay |
|
|
Compound concentration required to reduce the cell proliferation of Wild type and Drug- resistant human nasopharyngeal carcinoma KB cells by 50%, IC50 = 0.6 μM. |
12431048 |
P388 |
Growth inhibition assay |
|
|
Growth inhibitory activity against murine P388 leukemia cells, IC50 = 0.15 μM. |
12620081 |
HL60 |
Apoptosis assay |
|
|
In vitro concentration required to induce apoptosis in HL60 cells, AC50 = 0.45 μM. |
12877593 |
HL60R |
Apoptosis assay |
|
|
In vitro concentration required to induce apoptosis in HL60R cells, AC50 = 15 μM. |
12877593 |
HL60 |
Function assay |
|
|
In vitro inhibitory concentration against proliferation of HL60 cells, IC50 = 0.123 μM. |
12877593 |
HL60R |
Function assay |
|
|
In vitro inhibitory concentration against proliferation of HL60R cells, IC50 = 6.5 μM. |
12877593 |
HL60R |
Function assay |
|
|
In vitro inhibitory concentration against proliferation of HL60R cells along with 5 (uM) verapamil, IC50 = 0.5 μM. |
12877593 |
HL60 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HL60 cells by MTT assay, IC50 = 0.2 μM. |
14738377 |
KB |
Cytotoxicity assay |
|
|
Cytotoxicity against human KB cells, ID50 = 0.2 μM. |
14987069 |
KB |
Cytotoxicity assay |
|
|
Cytotoxicity against human KB cells, LD50 = 3 μM. |
14987069 |
MCF7 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MCF7 cells, GI50 = 4.36516 μM. |
14987069 |
MOLT4 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MOLT4 cells, GI50 = 1.02329 μM. |
14987069 |
HeLa |
Function assay |
|
|
Concentration required to inhibit S phase and G2/M phase in HeLa cells, Concentration = 2 μM. |
15026047 |
HeLa |
Growth inhibition assay |
|
|
Growth inhibitory concentration of compound was determined against HeLa cells by alamar blue assay, GI50 = 40 μM. |
15026047 |
A549 |
Function assay |
|
|
Effective dose on human lung carcinoma (A549) cells, ED50 = 3.39 μM. |
15914002 |
A549 |
Cytotoxicity assay |
|
|
Cytotoxicity against human A549 cells by SRB assay, IC50 = 1.16 μM. |
17194596 |
HCT116 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HCT116 cells by SRB assay, IC50 = 1.87 μM. |
17194596 |
HL60 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HL60 cells by SRB assay, IC50 = 0.37 μM. |
17194596 |
HT1080 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HT1080 cells by SRB assay, IC50 = 0.25 μM. |
17194596 |
SK-MEL-2 |
Cytotoxicity assay |
|
|
Cytotoxicity against human SK-MEL-2 cells by SRB assay, IC50 = 5.72 μM. |
17194596 |
SK-OV-3 |
Cytotoxicity assay |
|
|
Cytotoxicity against human SK-OV-3 cells by SRB assay, IC50 = 4.28 μM. |
17194596 |
SNU638 |
Cytotoxicity assay |
|
|
Cytotoxicity against human SNU638 cells by SRB assay, IC50 = 0.23 μM. |
17194596 |
XF498 |
Cytotoxicity assay |
|
|
Cytotoxicity against human XF498 cells by SRB assay, IC50 = 3.48 μM. |
17194596 |
HCT116 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HCT116 cells by XTT assay, IC50 = 1.7 μM. |
17368022 |
MCF7 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MCF7 cells by XTT assay, IC50 = 35.6 μM. |
17368022 |
MDA-MB468 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MDA-MB468 cells by XTT assay, IC50 = 13.6 μM. |
17368022 |
mouse astrocyte cells |
Antiproliferative assay |
|
|
Antiproliferative activity against mouse astrocyte cells by MTT assay, EC50 = 0.433 μM. |
17417631 |
mouse medulloblastoma cells |
Antiproliferative assay |
|
|
Antiproliferative activity against mouse medulloblastoma cells harboring heterozygous ptch1 gene by MTT assay, EC50 = 0.208 μM. |
17417631 |
mouse neural precursor cells |
Antiproliferative assay |
|
|
Antiproliferative activity against mouse neural precursor cells by MTT assay, EC50 = 0.34 μM. |
17417631 |
H460 |
Growth inhibition assay |
|
|
Growth inhibition of human H460 cells by MTT assay, IC50 = 0.2 μM. |
17482821 |
HeLa |
Growth inhibition assay |
|
|
Growth inhibition of human HeLa cells by MTT assay, IC50 = 2.9 μM. |
17482821 |
MiaPaCa2 |
Growth inhibition assay |
|
|
Growth inhibition of human MiaPaCa2 cells by MTT assay, IC50 = 15.4 μM. |
17482821 |
SW620 |
Growth inhibition assay |
|
|
Growth inhibition of human SW620 cells by MTT assay, IC50 = 20 μM. |
17482821 |
A549 |
Cytotoxicity assay |
|
|
Cytotoxicity against human A549 cells by SRB microtiter plate assay, IC50 = 1.4 μM. |
17585747 |
DU145 |
Cytotoxicity assay |
|
|
Cytotoxicity against human DU145 cells by SRB microtiter plate assay, IC50 = 2.4 μM. |
17585747 |
KB |
Cytotoxicity assay |
|
|
Cytotoxicity against human KB cells by SRB microtiter plate assay, IC50 = 4.8 μM. |
17585747 |
ZR751 |
Cytotoxicity assay |
|
|
Cytotoxicity against human ZR751cells by SRB microtiter plate assay, IC50 = 3.1 μM. |
17585747 |
HL60/MX2 |
Cytotoxicity assay |
|
|
Cytotoxicity against DNA topoisomerase-2 deficient human HL60/MX2 cells by MTT assay, GI50 = 5.98 μM. |
17962028 |
502713 |
Cytotoxicity assay |
|
|
Cytotoxicity against human 502713 cells by sulforhodamine B assay, IC50 = 2.42 μM. |
17988764 |
A549 |
Cytotoxicity assay |
|
|
Cytotoxicity against human A549 cells by sulforhodamine B assay, IC50 = 5.62 μM. |
17988764 |
DU145 |
Cytotoxicity assay |
|
|
Cytotoxicity against human DU145 cells by sulforhodamine B assay, IC50 = 3.85 μM. |
17988764 |
HCT-15 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HCT-15 cells by sulforhodamine B assay, IC50 = 1.48 μM. |
17988764 |
HEP2 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HEP2 cells by sulforhodamine B assay, IC50 = 2.15 μM. |
17988764 |
PC-3 |
Cytotoxicity assay |
|
|
Cytotoxicity against human PC-3 cells by sulforhodamine B assay, IC50 = 17.4 μM. |
17988764 |
SF295 |
Cytotoxicity assay |
|
|
Cytotoxicity against human SF295 cells by sulforhodamine B assay, IC50 = 13.3 μM. |
17988764 |
MCF7 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MCF7 cells by XTT assay, IC50 = 35.6 μM. |
18093835 |
DU145 |
Cytotoxicity assay |
|
|
Cytotoxicity against human DU145 cells, IC50 = 29.79 μM. |
18178085 |
HCT116 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HCT116 cells, IC50 = 15.11 μM. |
18178085 |
HeLa |
Cytotoxicity assay |
|
|
Cytotoxicity against human HeLa cells, IC50 = 18.24 μM. |
18178085 |
HL60 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HL60 cells, IC50 = 1.44 μM. |
18178085 |
MDA-MB-231 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MDA-MB-231 cells, IC50 = 16.25 μM. |
18178085 |
NCI-H520 |
Growth inhibition assay |
|
|
Growth inhibition of human NCI-H520 cells, GI50 = 13.5 μM. |
18502124 |
PC3 |
Growth inhibition assay |
|
|
Growth inhibition of human PC3 cells, GI50 = 12.5 μM. |
18502124 |
SK-Hep1 |
Cytotoxicity assay |
|
|
Cytotoxicity against human SK-Hep1 cells by MTT assay, IC50 = 49.6 μM. |
18637688 |
HL60 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HL60 cells by SRB assay, IC50 = 0.2 μM. |
18651771 |
A549 |
Cytotoxicity assay |
|
|
Cytotoxicity against human A549 cells assessed as reduction of cell growth by SRB method, IC50 = 9.98 μM. |
18782668 |
KB |
Cytotoxicity assay |
|
|
Cytotoxicity against human KB cells assessed as reduction of cell growth by SRB method, IC50 = 14.2 μM. |
18782668 |
A375 |
Cytotoxicity assay |
|
|
Cytotoxicity against human A375 cells by MTT assay, IC50 = 3.92 μM. |
19036584 |
A549 |
Cytotoxicity assay |
|
|
Cytotoxicity against human A549 cells by MTT assay, IC50 = 9.51 μM. |
19036584 |
HL60 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HL60 cells by MTT assay, IC50 = 1.83 μM. |
19036584 |
THP1 |
Cytotoxicity assay |
|
|
Cytotoxicity against human THP1 cells by MTT assay, IC50 = 2.16 μM. |
19036584 |
HCT15 |
Antiproliferative assay |
|
|
Antiproliferative activity against human HCT15 cells by SRB assay, GI50 = 1.25 μM. |
19394218 |
MESSA |
Antiproliferative assay |
|
|
Antiproliferative activity against human MESSA cells by SRB assay, GI50 = 0.21 μM. |
19394218 |
HCT15/CLO2 |
Antiproliferative assay |
|
|
Antiproliferative activity against multidrug resistant human HCT15/CLO2 cells by SRB assay, GI50 = 10.02 μM. |
19394218 |
MES-SA/Dx5 |
Antiproliferative assay |
|
|
Antiproliferative activity against multidrug resistant human MES-SA/Dx5 cells by SRB assay, GI50 = 9.72 μM. |
19394218 |
A375 |
Cytotoxicity assay |
|
|
Cytotoxicity against human A375 cells by MTT assay, IC50 = 3.92 μM. |
19782567 |
A549 |
Cytotoxicity assay |
|
|
Cytotoxicity against human A549 cells by MTT assay, IC50 = 9.51 μM. |
19782567 |
HL60 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HL60 cells by MTT assay, IC50 = 2.16 μM. |
19782567 |
THP1 |
Cytotoxicity assay |
|
|
Cytotoxicity against human THP1 cells by MTT assay, IC50 = 1.83 μM. |
19782567 |
H69 |
Cytotoxicity assay |
|
|
Cytotoxicity against human adriamycin resistant H69 cells, IC50 = 46 μM. |
19788270 |
HeLa |
Cytotoxicity assay |
|
|
Cytotoxicity against human HeLa cells, IC50 = 0.4 μM. |
19788270 |
HuCCa1 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HuCCa1 cells, IC50 = 5.1 μM. |
19788270 |
KB |
Cytotoxicity assay |
|
|
Cytotoxicity against human KB cells, IC50 = 0.5 μM. |
19788270 |
MDA-MB-231 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MDA-MB-231 cells, IC50 = 0.3 μM. |
19788270 |
T47D |
Cytotoxicity assay |
|
|
Cytotoxicity against human T47D cells, IC50 = 0.1 μM. |
19788270 |
DU145 |
Cytotoxicity assay |
|
|
Cytotoxicity against human DU145 cells by MTT assay, IC50 = 5.16 μM. |
19836231 |
HeLa |
Cytotoxicity assay |
|
|
Cytotoxicity against human HeLa cells by MTT assay, IC50 = 2.15 μM. |
19836231 |
HL60 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HL60 cells by MTT assay, IC50 = 0.93 μM. |
19836231 |
HT-29 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HT-29 cells by MTT assay, IC50 = 6.32 μM. |
19836231 |
MDA-MB-231 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MDA-MB-231 cells by MTT assay, IC50 = 3.5 μM. |
19836231 |
KB |
Cytotoxicity assay |
|
|
Cytotoxicity against human KB cells, EC50 = 1.1 μM. |
20102168 |
DU145 |
Cytotoxicity assay |
|
|
Cytotoxicity against human DU145 cells in presence of 10% fetal bovine serum, IC50 = 2.45 μM. |
20188578 |
HCT15 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HCT15 cells in presence of 10% fetal bovine serum, IC50 = 1.29 μM. |
20188578 |
HeLa |
Cytotoxicity assay |
|
|
Cytotoxicity against human HeLa cells in presence of 10% fetal bovine serum, IC50 = 1.57 μM. |
20188578 |
K562 |
Cytotoxicity assay |
|
|
Cytotoxicity against human K562 cells in presence of 10% fetal bovine serum, IC50 = 2.84 μM. |
20188578 |
HeLa |
Cytotoxicity assay |
|
|
Cytotoxicity against human HeLa cells by MTT assay, IC50 = 8.93 μM. |
20356735 |
HL60 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HL60 cells by MTT assay, IC50 = 1.81 μM. |
20356735 |
HL60 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HL60 cells, IC50 = 0.49 μM. |
20863598 |
NCI60 |
Growth inhibition assay |
|
|
Growth inhibition of human NCI60 cells by SBR assay, GI50 = 38.9045 μM. |
21035334 |
DU145 |
Cytotoxicity assay |
|
|
Cytotoxicity against human DU145 cells by MTT assay, IC50 = 1.44 μM. |
21115246 |
HCT15 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HCT15 cells by MTT assay, IC50 = 2.03 μM. |
21115246 |
K562 |
Cytotoxicity assay |
|
|
Cytotoxicity against human K562 cells by MTT assay, IC50 = 1.21 μM. |
21115246 |
MCF7 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MCF7 cells by MTT assay, IC50 = 1.98 μM. |
21115246 |
HepG2 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HepG2 cells by MTT assay, IC50 = 15.8 μM. |
21174408 |
MOLT3 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MOLT3 cells by XTT assay, IC50 = 0.03 μM. |
21174408 |
A549 |
Cytotoxicity assay |
|
|
Cytotoxicity against human A549 cells by SRB assay, IC50 = 1.85 μM. |
21182258 |
SK-MEL-2 |
Cytotoxicity assay |
|
|
Cytotoxicity against human SK-MEL-2 cells by SRB assay, IC50 = 1.17 μM. |
21182258 |
SKOV3 |
Cytotoxicity assay |
|
|
Cytotoxicity against human SKOV3 cells by SRB assay, IC50 = 1.81 μM. |
21182258 |
XF498 |
Cytotoxicity assay |
|
|
Cytotoxicity against human XF498 cells by SRB assay, IC50 = 1.72 μM. |
21182258 |
A549 |
Anticancer assay |
|
|
Anticancer activity against human A549 cells by SRB assay, IC50 = 1.85 μM. |
21420296 |
SK-MEL-2 |
Anticancer assay |
|
|
Anticancer activity against human SK-MEL-2 cells by SRB assay, IC50 = 1.17 μM. |
21420296 |
SKOV3 |
Anticancer assay |
|
|
Anticancer activity against human SKOV3 cells by SRB assay, IC50 = 1.81 μM. |
21420296 |
XF498 |
Anticancer assay |
|
|
Anticancer activity against human XF498 cells by SRB assay, IC50 = 1.72 μM. |
21420296 |
HL60 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HL60 cells, IC50 = 1.4 μM. |
21439821 |
HL60/MX2 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HL60/MX2 cells, IC50 = 15.75 μM. |
21439821 |
A549 |
Cytotoxicity assay |
|
|
Cytotoxicity against human A549 cells by sulforhodamine B assay, IC50 = 0.44 μM. |
21936523 |
SK-MEL-2 |
Cytotoxicity assay |
|
|
Cytotoxicity against human SK-MEL-2 cells by sulforhodamine B assay, IC50 = 0.41 μM. |
21936523 |
SKOV3 |
Cytotoxicity assay |
|
|
Cytotoxicity against human SKOV3 cells by sulforhodamine B assay, IC50 = 1.31 μM. |
21936523 |
HBL100 |
Growth inhibition assay |
|
|
Growth inhibition of human HBL100 cells, GI50 = 2.3 μM. |
21986585 |
HeLa |
Growth inhibition assay |
|
|
Growth inhibition of human HeLa cells, GI50 = 3 μM. |
21986585 |
Ishikawa |
Growth inhibition assay |
|
|
Growth inhibition of human Ishikawa cells, GI50 = 11 μM. |
21986585 |
SW1573 |
Growth inhibition assay |
|
|
Growth inhibition of human SW1573 cells, GI50 = 15 μM. |
21986585 |
T47D |
Growth inhibition assay |
|
|
Growth inhibition of human T47D cells, GI50 = 22 μM. |
21986585 |
WiDr |
Growth inhibition assay |
|
|
Growth inhibition of human WiDr cells, GI50 = 23 μM. |
21986585 |
Bel7402 |
Cytotoxicity assay |
|
|
Cytotoxicity against human Bel7402 cells, IC50 = 0.08 μM. |
23092389 |
HeLa |
Cytotoxicity assay |
|
|
Cytotoxicity against human HeLa cells, IC50 = 0.08 μM. |
23092389 |
SGC7901 |
Cytotoxicity assay |
|
|
Cytotoxicity against human SGC7901 cells, IC50 = 0.08 μM. |
23092389 |
P388 |
Cytotoxicity assay |
|
|
Cytotoxicity against mouse P388 cells, IC50 = 0.08 μM. |
23092389 |
SNU638 |
Cytotoxicity assay |
|
|
Cytotoxicity against human SNU638 cells by MTT assay, IC50 = 2.57 μM. |
23608763 |
T47D |
Cytotoxicity assay |
|
|
Cytotoxicity against human T47D cells by MTT assay, IC50 = 4.98 μM. |
23608763 |
H460 |
Cytotoxicity assay |
|
|
Cytotoxicity against human H460 cells assessed as growth inhibition by MTT assay, IC50 = 30 μM. |
23920485 |
MCF7 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MCF7 cells assessed as growth inhibition by MTT assay, IC50 = 20.9 μM. |
23920485 |
PC3 |
Cytotoxicity assay |
|
|
Cytotoxicity against human PC3 cells assessed as growth inhibition by MTT assay, IC50 = 18.2 μM. |
23920485 |
HeLa |
Cytotoxicity assay |
|
|
Cytotoxicity against human HeLa cells by MTT assay, IC50 = 0.0057 μM. |
24422592 |
BGC823 |
Cytotoxicity assay |
|
|
Cytotoxicity against human BGC823 cells, IC50 = 25.72 μM. |
24775914 |
HepG2 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HepG2 cells, IC50 = 1.15 μM. |
24775914 |
KB |
Antiproliferative assay |
|
|
Antiproliferative activity against human KB cells, IC50 = 1.1 μM. |
25059503 |
KB-S15 |
Antiproliferative assay |
|
|
Antiproliferative activity against human KB-S15 cells, IC50 = 3.5 μM. |
25059503 |
KB-VIN10 |
Antiproliferative assay |
|
|
Antiproliferative activity against human KB-VIN10 cells, IC50 = 23 μM. |
25059503 |
SKMES1 |
Cytotoxicity assay |
|
|
Cytotoxicity against human SKMES1 cells, IC50 = 1.83 μM. |
25440884 |
HepG2 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HepG2 cells by MTT assay, IC50 = 40.47 μM. |
25747499 |
MOLT3 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MOLT3 cells by XTT assay, IC50 = 0.11 μM. |
25747499 |
MCF7 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MCF7 cells by MTT assay, IC50 = 7.6 μM. |
25847767 |
MDA-MB-231 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MDA-MB-231 cells by MTT assay, IC50 = 10.3 μM. |
25847767 |
T47D |
Cytotoxicity assay |
|
|
Cytotoxicity against human T47D cells by MTT assay, IC50 = 8.9 μM. |
25847767 |
A549 |
Antiproliferative assay |
|
|
Antiproliferative activity against human A549 cells by MTT assay, IC50 = 18.2 μM. |
26216018 |
HepG2 |
Antiproliferative assay |
|
|
Antiproliferative activity against human HepG2 cells by MTT assay, IC50 = 20.9 μM. |
26216018 |
A549 |
Cytotoxicity assay |
|
|
Cytotoxicity in human A549 cells by SRB assay, IC50 = 1.4 μM. |
26812172 |
HCT116 |
Cytotoxicity assay |
|
|
Cytotoxicity in human HCT116 cells by SRB assay, IC50 = 1 μM. |
26812172 |
SK-MEL-2 |
Cytotoxicity assay |
|
|
Cytotoxicity in human SK-MEL-2 cells by SRB assay, IC50 = 1.5 μM. |
26812172 |
SKOV3 |
Cytotoxicity assay |
|
|
Cytotoxicity in human SKOV3 cells by SRB assay, IC50 = 2.6 μM. |
26812172 |
A549 |
Cytotoxicity assay |
|
|
Cytotoxicity against human A549 cells by SRB assay, IC50 = 1.85 μM. |
26988298 |
SK-MEL-2 |
Cytotoxicity assay |
|
|
Cytotoxicity against human SK-MEL-2 cells by SRB assay, IC50 = 1.17 μM. |
26988298 |
SKOV3 |
Cytotoxicity assay |
|
|
Cytotoxicity against human SKOV3 cells by SRB assay, IC50 = 0.84 μM. |
26988298 |
XF498 |
Cytotoxicity assay |
|
|
Cytotoxicity against human XF498 cells by SRB assay, IC50 = 1.72 μM. |
26988298 |
HL60 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HL60 cells assessed as reduction in cell survival, IC50 = 0.025 μM. |
27234147 |
HepG2 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HepG2 cells by MTT assay, IC50 = 15.8 μM. |
27759375 |
HCT116 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HCT116 cells assessed as growth inhibition by MTS assay, IC50 = 0.49 μM. |
28055208 |
A549 |
Cytotoxicity assay |
|
|
Cytotoxicity against human A549 cells assessed as reduction in cell viability by MTT assay, IC50 = 16.6 μM. |
28571311 |
HeLa |
Cytotoxicity assay |
|
|
Cytotoxicity against human HeLa cells assessed as reduction in cell viability by MTT assay, IC50 = 15 μM. |
28571311 |
HepG2 |
Cytotoxicity assay |
|
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay, IC50 = 16.1 μM. |
28571311 |
MCF7 |
Cytotoxicity assay |
|
|
Cytotoxicity against human MCF7 cells by MTT assay, IC50 = 12.4 μM. |
28886509 |
HeLaS3 |
Antiproliferative assay |
|
|
Antiproliferative activity against human HeLaS3 cells by MTT assay, IC50 = 0.5 μM. |
29072457 |
HT-29 |
Antiproliferative assay |
|
|
Antiproliferative activity against human HT-29 cells by MTT assay, IC50 = 7.6 μM. |
29072457 |
K562 |
Antiproliferative assay |
|
|
Antiproliferative activity against human K562 cells, IC50 = 0.3 μM. |
29871847 |
K/VP.5 |
Function assay |
|
|
Inhibition of human topoisomerase-2 in etoposide-resistant K/VP.5 cells assessed as growth inhibition, IC50 = 5.1 μM. |
29871847 |
RH-1 |
Growth inhibition assay |
|
|
IC50 = 0.01778 μM |
SANGER |
A253 |
Growth inhibition assay |
|
|
IC50 = 0.01843 μM |
SANGER |
HT-144 |
Growth inhibition assay |
|
|
IC50 = 0.02009 μM |
SANGER |
EW-16 |
Growth inhibition assay |
|
|
IC50 = 0.02148 μM |
SANGER |
NTERA-S-cl-D1 |
Growth inhibition assay |
|
|
IC50 = 0.02502 μM |
SANGER |
KE-37 |
Growth inhibition assay |
|
|
IC50 = 0.04072 μM |
SANGER |
SK-UT-1 |
Growth inhibition assay |
|
|
IC50 = 0.04237 μM |
SANGER |
OCUB-M |
Growth inhibition assay |
|
|
IC50 = 0.04455 μM |
SANGER |
8-MG-BA |
Growth inhibition assay |
|
|
IC50 = 0.04687 μM |
SANGER |
TE-9 |
Growth inhibition assay |
|
|
IC50 = 0.05593 μM |
SANGER |
CGTH-W-1 |
Growth inhibition assay |
|
|
IC50 = 0.05741 μM |
SANGER |
BB30-HNC |
Growth inhibition assay |
|
|
IC50 = 0.06418 μM |
SANGER |
ACN |
Growth inhibition assay |
|
|
IC50 = 0.07896 μM |
SANGER |
EW-13 |
Growth inhibition assay |
|
|
IC50 = 0.08885 μM |
SANGER |
DU-4475 |
Growth inhibition assay |
|
|
IC50 = 0.09615 μM |
SANGER |
HGC-27 |
Growth inhibition assay |
|
|
IC50 = 0.10212 μM |
SANGER |
A427 |
Growth inhibition assay |
|
|
IC50 = 0.10338 μM |
SANGER |
HT-1080 |
Growth inhibition assay |
|
|
IC50 = 0.10853 μM |
SANGER |
MC-IXC |
Growth inhibition assay |
|
|
IC50 = 0.11512 μM |
SANGER |
MRK-nu-1 |
Growth inhibition assay |
|
|
IC50 = 0.1162 μM |
SANGER |
EW-7 |
Growth inhibition assay |
|
|
IC50 = 0.12506 μM |
SANGER |
SW982 |
Growth inhibition assay |
|
|
IC50 = 0.13069 μM |
SANGER |
SIG-M5 |
Growth inhibition assay |
|
|
IC50 = 0.13082 μM |
SANGER |
PA-1 |
Growth inhibition assay |
|
|
IC50 = 0.13219 μM |
SANGER |
ES8 |
Growth inhibition assay |
|
|
IC50 = 0.14221 μM |
SANGER |
MV-4-11 |
Growth inhibition assay |
|
|
IC50 = 0.15121 μM |
SANGER |
QIMR-WIL |
Growth inhibition assay |
|
|
IC50 = 0.15458 μM |
SANGER |
COLO-679 |
Growth inhibition assay |
|
|
IC50 = 0.16303 μM |
SANGER |
CCRF-CEM |
Growth inhibition assay |
|
|
IC50 = 0.17043 μM |
SANGER |
IGROV-1 |
Growth inhibition assay |
|
|
IC50 = 0.17072 μM |
SANGER |
LOUCY |
Growth inhibition assay |
|
|
IC50 = 0.1766 μM |
SANGER |
ML-2 |
Growth inhibition assay |
|
|
IC50 = 0.17847 μM |
SANGER |
RS4-11 |
Growth inhibition assay |
|
|
IC50 = 0.19612 μM |
SANGER |
DJM-1 |
Growth inhibition assay |
|
|
IC50 = 0.20294 μM |
SANGER |
ATN-1 |
Growth inhibition assay |
|
|
IC50 = 0.20386 μM |
SANGER |
NALM-6 |
Growth inhibition assay |
|
|
IC50 = 0.20584 μM |
SANGER |
HUTU-80 |
Growth inhibition assay |
|
|
IC50 = 0.21676 μM |
SANGER |
REH |
Growth inhibition assay |
|
|
IC50 = 0.22424 μM |
SANGER |
NCI-H2030 |
Growth inhibition assay |
|
|
IC50 = 0.22992 μM |
SANGER |
A204 |
Growth inhibition assay |
|
|
IC50 = 0.23248 μM |
SANGER |
NCI-H460 |
Growth inhibition assay |
|
|
IC50 = 0.23571 μM |
SANGER |
697 |
Growth inhibition assay |
|
|
IC50 = 0.2432 μM |
SANGER |
KYSE-270 |
Growth inhibition assay |
|
|
IC50 = 0.25188 μM |
SANGER |
ES1 |
Growth inhibition assay |
|
|
IC50 = 0.25434 μM |
SANGER |
COLO-205 |
Growth inhibition assay |
|
|
IC50 = 0.26497 μM |
SANGER |
SK-HEP-1 |
Growth inhibition assay |
|
|
IC50 = 0.26712 μM |
SANGER |
RPMI-8402 |
Growth inhibition assay |
|
|
IC50 = 0.27109 μM |
SANGER |
H4 |
Growth inhibition assay |
|
|
IC50 = 0.29654 μM |
SANGER |
LU-134-A |
Growth inhibition assay |
|
|
IC50 = 0.29919 μM |
SANGER |
EoL-1-cell |
Growth inhibition assay |
|
|
IC50 = 0.30172 μM |
SANGER |
SBC-5 |
Growth inhibition assay |
|
|
IC50 = 0.30262 μM |
SANGER |
DEL |
Growth inhibition assay |
|
|
IC50 = 0.31149 μM |
SANGER |
P12-ICHIKAWA |
Growth inhibition assay |
|
|
IC50 = 0.31679 μM |
SANGER |
AGS |
Growth inhibition assay |
|
|
IC50 = 0.31823 μM |
SANGER |
KS-1 |
Growth inhibition assay |
|
|
IC50 = 0.33444 μM |
SANGER |
SK-PN-DW |
Growth inhibition assay |
|
|
IC50 = 0.34228 μM |
SANGER |
DOHH-2 |
Growth inhibition assay |
|
|
IC50 = 0.34733 μM |
SANGER |
KGN |
Growth inhibition assay |
|
|
IC50 = 0.35189 μM |
SANGER |
A3-KAW |
Growth inhibition assay |
|
|
IC50 = 0.35826 μM |
SANGER |
M059J |
Growth inhibition assay |
|
|
IC50 = 0.36401 μM |
SANGER |
Daoy |
Growth inhibition assay |
|
|
IC50 = 0.36773 μM |
SANGER |
MKN1 |
Growth inhibition assay |
|
|
IC50 = 0.38169 μM |
SANGER |
CESS |
Growth inhibition assay |
|
|
IC50 = 0.38386 μM |
SANGER |
SW620 |
Growth inhibition assay |
|
|
IC50 = 0.38448 μM |
SANGER |
NCI-H1355 |
Growth inhibition assay |
|
|
IC50 = 0.38972 μM |
SANGER |
EB2 |
Growth inhibition assay |
|
|
IC50 = 0.39146 μM |
SANGER |
ABC-1 |
Growth inhibition assay |
|
|
IC50 = 0.40453 μM |
SANGER |
GT3TKB |
Growth inhibition assay |
|
|
IC50 = 0.40644 μM |
SANGER |
CTV-1 |
Growth inhibition assay |
|
|
IC50 = 0.40969 μM |
SANGER |
VA-ES-BJ |
Growth inhibition assay |
|
|
IC50 = 0.41481 μM |
SANGER |
KP-4 |
Growth inhibition assay |
|
|
IC50 = 0.41615 μM |
SANGER |
MOLT-4 |
Growth inhibition assay |
|
|
IC50 = 0.41754 μM |
SANGER |
NKM-1 |
Growth inhibition assay |
|
|
IC50 = 0.42516 μM |
SANGER |
A2058 |
Growth inhibition assay |
|
|
IC50 = 0.42537 μM |
SANGER |
BFTC-905 |
Growth inhibition assay |
|
|
IC50 = 0.42621 μM |
SANGER |
SR |
Growth inhibition assay |
|
|
IC50 = 0.44265 μM |
SANGER |
NCI-H526 |
Growth inhibition assay |
|
|
IC50 = 0.45612 μM |
SANGER |
MES-SA |
Growth inhibition assay |
|
|
IC50 = 0.45821 μM |
SANGER |
MHH-ES-1 |
Growth inhibition assay |
|
|
IC50 = 0.46271 μM |
SANGER |
IMR-5 |
Growth inhibition assay |
|
|
IC50 = 0.46935 μM |
SANGER |
RKO |
Growth inhibition assay |
|
|
IC50 = 0.47075 μM |
SANGER |
HOS |
Growth inhibition assay |
|
|
IC50 = 0.47376 μM |
SANGER |
647-V |
Growth inhibition assay |
|
|
IC50 = 0.48734 μM |
SANGER |
786-0 |
Growth inhibition assay |
|
|
IC50 = 0.4922 μM |
SANGER |
Calu-3 |
Growth inhibition assay |
|
|
IC50 = 0.49556 μM |
SANGER |
U251 |
Growth inhibition assay |
|
|
IC50 = 0.50083 μM |
SANGER |
23132-87 |
Growth inhibition assay |
|
|
IC50 = 0.50139 μM |
SANGER |
BE-13 |
Growth inhibition assay |
|
|
IC50 = 0.50368 μM |
SANGER |
SW1710 |
Growth inhibition assay |
|
|
IC50 = 0.51838 μM |
SANGER |
ES4 |
Growth inhibition assay |
|
|
IC50 = 0.52145 μM |
SANGER |
HOP-62 |
Growth inhibition assay |
|
|
IC50 = 0.52437 μM |
SANGER |
MHH-NB-11 |
Growth inhibition assay |
|
|
IC50 = 0.52443 μM |
SANGER |
KYSE-150 |
Growth inhibition assay |
|
|
IC50 = 0.53039 μM |
SANGER |
ESS-1 |
Growth inhibition assay |
|
|
IC50 = 0.53078 μM |
SANGER |
HLE |
Growth inhibition assay |
|
|
IC50 = 0.53357 μM |
SANGER |
NEC8 |
Growth inhibition assay |
|
|
IC50 = 0.53895 μM |
SANGER |
HC-1 |
Growth inhibition assay |
|
|
IC50 = 0.54032 μM |
SANGER |
BC-1 |
Growth inhibition assay |
|
|
IC50 = 0.54533 μM |
SANGER |
SK-LMS-1 |
Growth inhibition assay |
|
|
IC50 = 0.5528 μM |
SANGER |
NCI-H2342 |
Growth inhibition assay |
|
|
IC50 = 0.55508 μM |
SANGER |
OCI-AML2 |
Growth inhibition assay |
|
|
IC50 = 0.55935 μM |
SANGER |
KYSE-510 |
Growth inhibition assay |
|
|
IC50 = 0.56639 μM |
SANGER |
HMV-II |
Growth inhibition assay |
|
|
IC50 = 0.56879 μM |
SANGER |
RPMI-2650 |
Growth inhibition assay |
|
|
IC50 = 0.57196 μM |
SANGER |
DMS-273 |
Growth inhibition assay |
|
|
IC50 = 0.57348 μM |
SANGER |
MC-CAR |
Growth inhibition assay |
|
|
IC50 = 0.57962 μM |
SANGER |
DU-145 |
Growth inhibition assay |
|
|
IC50 = 0.59125 μM |
SANGER |
HCC1599 |
Growth inhibition assay |
|
|
IC50 = 0.61627 μM |
SANGER |
RT-112 |
Growth inhibition assay |
|
|
IC50 = 0.62053 μM |
SANGER |
CAL-148 |
Growth inhibition assay |
|
|
IC50 = 0.62544 μM |
SANGER |
ES3 |
Growth inhibition assay |
|
|
IC50 = 0.62849 μM |
SANGER |
A375 |
Growth inhibition assay |
|
|
IC50 = 0.63084 μM |
SANGER |
SW872 |
Growth inhibition assay |
|
|
IC50 = 0.6404 μM |
SANGER |
LCLC-103H |
Growth inhibition assay |
|
|
IC50 = 0.6511 μM |
SANGER |
MEL-JUSO |
Growth inhibition assay |
|
|
IC50 = 0.6571 μM |
SANGER |
NH-12 |
Growth inhibition assay |
|
|
IC50 = 0.67198 μM |
SANGER |
NCI-H187 |
Growth inhibition assay |
|
|
IC50 = 0.67362 μM |
SANGER |
CAL-33 |
Growth inhibition assay |
|
|
IC50 = 0.6858 μM |
SANGER |
ALL-PO |
Growth inhibition assay |
|
|
IC50 = 0.68979 μM |
SANGER |
8505C |
Growth inhibition assay |
|
|
IC50 = 0.69275 μM |
SANGER |
NCI-H2009 |
Growth inhibition assay |
|
|
IC50 = 0.69655 μM |
SANGER |
KURAMOCHI |
Growth inhibition assay |
|
|
IC50 = 0.6986 μM |
SANGER |
HSC-2 |
Growth inhibition assay |
|
|
IC50 = 0.70578 μM |
SANGER |
SUP-T1 |
Growth inhibition assay |
|
|
IC50 = 0.70586 μM |
SANGER |
GI-1 |
Growth inhibition assay |
|
|
IC50 = 0.71317 μM |
SANGER |
TUR |
Growth inhibition assay |
|
|
IC50 = 0.72224 μM |
SANGER |
PF-382 |
Growth inhibition assay |
|
|
IC50 = 0.72388 μM |
SANGER |
MEL-HO |
Growth inhibition assay |
|
|
IC50 = 0.72874 μM |
SANGER |
BCPAP |
Growth inhibition assay |
|
|
IC50 = 0.73695 μM |
SANGER |
MFH-ino |
Growth inhibition assay |
|
|
IC50 = 0.7513 μM |
SANGER |
ONS-76 |
Growth inhibition assay |
|
|
IC50 = 0.75429 μM |
SANGER |
MFE-296 |
Growth inhibition assay |
|
|
IC50 = 0.76297 μM |
SANGER |
NCI-H2087 |
Growth inhibition assay |
|
|
IC50 = 0.76306 μM |
SANGER |
LCLC-97TM1 |
Growth inhibition assay |
|
|
IC50 = 0.76624 μM |
SANGER |
ES7 |
Growth inhibition assay |
|
|
IC50 = 0.76713 μM |
SANGER |
A431 |
Growth inhibition assay |
|
|
IC50 = 0.79754 μM |
SANGER |
HCE-4 |
Growth inhibition assay |
|
|
IC50 = 0.80135 μM |
SANGER |
SK-MES-1 |
Growth inhibition assay |
|
|
IC50 = 0.80842 μM |
SANGER |
MZ1-PC |
Growth inhibition assay |
|
|
IC50 = 0.8111 μM |
SANGER |
ME-180 |
Growth inhibition assay |
|
|
IC50 = 0.8238 μM |
SANGER |
MCF7 |
Growth inhibition assay |
|
|
IC50 = 0.8305 μM |
SANGER |
G-361 |
Growth inhibition assay |
|
|
IC50 = 0.83387 μM |
SANGER |
ACHN |
Growth inhibition assay |
|
|
IC50 = 0.83874 μM |
SANGER |
A4-Fuk |
Growth inhibition assay |
|
|
IC50 = 0.84103 μM |
SANGER |