GSK269962A HCl

目录号:S7687 别名: GSK269962B, GSK269962, GSK 269962

GSK269962A HCl Chemical Structure

Molecular Weight(MW): 607.06

GSK269962是选择性的ROCK(Rho-associated protein kinase)抑制剂,对ROCK1和ROCK2的IC50分别为1.6 nM和4 nM。

规格 价格 库存 购买数量  
RMB 794.65 现货
RMB 3252.41 现货
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产品安全说明书

ROCK抑制剂选择性比较

生物活性

产品描述 GSK269962是选择性的ROCK(Rho-associated protein kinase)抑制剂,对ROCK1和ROCK2的IC50分别为1.6 nM和4 nM。
靶点
ROCK1 [1]
(Cell-free assay)
ROCK2 [1]
(Cell-free assay)
MSK1 [1]
(Cell-free assay)
RSK1 [1]
(Cell-free assay)
1.6 nM 4 nM 49 nM 132 nM
体外研究

GSK269962A在人类平滑肌中,完全阻断血管紧张肽Ⅱ诱导的肌动蛋白张力丝的形成。这一抑制现象始于约1 μM GSK269962A。GSK269962A在预束紧的大鼠动脉(组织浴/组织培养)中诱导血管舒张,IC50为35 nM。GSK269962A所诱导的舒张是可逆的。GSK269962A在巨噬细胞中抑制IL-6 mRNA的转录、减少LPS诱导的IL-6和TNF-α蛋白的产生[1]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1581 NFuxPY1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoTSTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG1PFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yQC56NEe3JO69VQ>? NWqwPG5qW0GQR1XS
NCI-H1694 NIe5UFhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NH7oOnlKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVY6PCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ2Lki3OFkh|ryP M{PpXXNCVkeHUh?=
NCI-H1963 NGTESZhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVHJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUm2N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvOjd6M{mg{txO M33XS3NCVkeHUh?=
NCI-H2081 M1nFc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MX;Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkC4NUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM1NjZyNESg{txO NUXCdodVW0GQR1XS
NCI-H209 NVXWTpZrT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mli1TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKwPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIzNjZ{N{Kg{txO M4q5U3NCVkeHUh?=
NCI-H2107 NUX1[ZB2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYDJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkGwO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI2NjZ3NkGg{txO MWjTRW5ITVJ?
NCI-H2126 NUnXNW5jT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUHOWo5xUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyOjZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD14LkWwOFI3KM7:TR?= NHHDRVZUSU6JRWK=
NCI-H2171 MnXMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlLwTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxO|Eh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjl3OUO3JO69VQ>? NIP0Wm1USU6JRWK=
NCI-H2227 MlrqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlT6TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKyNlch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF04Njh6NkG2JO69VQ>? MXzTRW5ITVJ?
NCI-H524 NVLlNFJFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnPvTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEWyOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIzNjh5NkOg{txO MkW3V2FPT0WU
NCI-H526 MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXPJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KNUK2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVgvPTR|MTFOwG0> M4e1TnNCVkeHUh?=
NCI-H720 MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{G3ZWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi3NlAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjR3MU[xJO69VQ>? NF\OVGFUSU6JRWK=
NMC-G1 MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUXJcohq[mm2aX;uJI9nKGi3bXHuJG5OSy2JMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG1MlA2PzhizszN MWDTRW5ITVJ?
NOS-1 cell NFHhXVRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGTVNmJKdmirYnn0bY9vKG:oIHj1cYFvKE6RUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OU45OjJ7NDFOwG0> NXXwRoJZW0GQR1XS
OCI-AML2 cell NUf6NWNRT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVXBR2RJUW6qaXLpeIlwdiCxZjDoeY1idiCRQ1mtRW1NOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFyLkm0PVYh|ryP NGjwU4hUSU6JRWK=
OCUB-M cell MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3rhcGlvcGmkaYTpc44hd2ZiaIXtZY4hV0OXQj3NJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVcvOjBzIN88US=> M2XHNnNCVkeHUh?=
ONS-76 cell NGPjZohIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1PyOGlvcGmkaYTpc44hd2ZiaIXtZY4hV06VLUe2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvQTF7MTFOwG0> MoPtV2FPT0WU
OS-RC-2 cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUfJcohq[mm2aX;uJI9nKGi3bXHuJG9UNVKFLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Ok4yQTVizszN M3Xse3NCVkeHUh?=
OVCAR-4 cell M37oV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MoD3TY5pcWKrdHnvckBw\iCqdX3hckBQXkODUj20JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE44OThyODFOwG0> MWnTRW5ITVJ?
P30-OHK cell MlS4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NI\XbFNKdmirYnn0bY9vKG:oIHj1cYFvKFB|MD3PTGsh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF04NjZ{OEe3JO69VQ>? MUTTRW5ITVJ?
P30-OHK cell NIH6emZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NE\KUlhKdmirYnn0bY9vKG:oIHj1cYFvKFCILUO4NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvODR7NUSg{txO NWTCe2loW0GQR1XS
PSN1 cell M4[4b2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYHJcohq[mm2aX;uJI9nKGi3bXHuJHBUVjFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD14LkKyNVI3KM7:TR?= M2TOdHNCVkeHUh?=
QIMR-WIL cell MVHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlzNTY5pcWKrdHnvckBw\iCqdX3hckBSUU2ULWfJUEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPDlyMESg{txO Mn72V2FPT0WU
RCC10RGB cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4WxWmlvcGmkaYTpc44hd2ZiaIXtZY4hWkOFMUDSS2Ih[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yQC57MEO2JO69VQ>? M2nWTHNCVkeHUh?=
RKO cell MoLVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH3XZ3NKdmirYnn0bY9vKG:oIHj1cYFvKFKNTzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGwMlU3PjJizszN MU\TRW5ITVJ?
RL95-2 cell M1PXWGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVXJcohq[mm2aX;uJI9nKGi3bXHuJHJNQTVvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGwMlY4KM7:TR?= MUfTRW5ITVJ?
RPMI-6666 cell MV3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1rURWlvcGmkaYTpc44hd2ZiaIXtZY4hWlCPST22OlY3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwNUKzOkDPxE1? NGTKU4xUSU6JRWK=
RPMI-8402 cell MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnjjTY5pcWKrdHnvckBw\iCqdX3hckBTWE2LLUi0NFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjV6NU[g{txO NFHnfnZUSU6JRWK=
RXF393 cell NWjT[ZNnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHrvT|FKdmirYnn0bY9vKG:oIHj1cYFvKFK[RkO5N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzl|IN88US=> MlXrV2FPT0WU
Ramos-2G6-4C10 cell NXzydYt4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1XnXmlvcGmkaYTpc44hd2ZiaIXtZY4hWmGvb4OtNmc3NTSFMUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlM2PyEQvF2= MV\TRW5ITVJ?
SCLC-21H cell MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MV7Jcohq[mm2aX;uJI9nKGi3bXHuJHNEVENvMkHIJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{43OTF2OTFOwG0> NHmxNZdUSU6JRWK=
SF126 cell NGDBcGtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEnBS5pKdmirYnn0bY9vKG:oIHj1cYFvKFOIMUK2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVEvQDN{Md88US=> NG\6eGtUSU6JRWK=
SF268 cell NHH3T2NIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M33keGlvcGmkaYTpc44hd2ZiaIXtZY4hW0Z{NkigZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME22MlI{OTh|IN88US=> NGey[IlUSU6JRWK=
SF539 cell MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYrJcohq[mm2aX;uJI9nKGi3bXHuJHNHPTN7IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6yPFY3OSEQvF2= M2PlbHNCVkeHUh?=
SH-4 cell MnPQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MX7Jcohq[mm2aX;uJI9nKGi3bXHuJHNJNTRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13Lke1OVA5KM7:TR?= M4DaPXNCVkeHUh?=
SIG-M5 cell NFL6NnBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1K3PWlvcGmkaYTpc44hd2ZiaIXtZY4hW0mJLV21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVEvPzJ3OTFOwG0> MkP2V2FPT0WU
SJSA-1 cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYe2OVJJUW6qaXLpeIlwdiCxZjDoeY1idiCVSmPBMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjB2NUK2JO69VQ>? MXTTRW5ITVJ?
SK-LMS-1 cell MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFrJVJlKdmirYnn0bY9vKG:oIHj1cYFvKFONLVzNV{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzJwNUm2OUDPxE1? NVPvcJkxW0GQR1XS
SK-MM-2 cell MoewS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4racGlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTV2tNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQzNjN2MEWg{txO MnT4V2FPT0WU
SK-N-DZ cell M{nUfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2\vcmlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTj3EXkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVkvPDh|MUSg{txO NUPSOnNOW0GQR1XS
SK-NEP-1 cell MnzsS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFnlVIFKdmirYnn0bY9vKG:oIHj1cYFvKFONLV7FVE0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTdwNUS1OkDPxE1? NHP4SohUSU6JRWK=
SK-PN-DW cell MYnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NH7pUnFKdmirYnn0bY9vKG:oIHj1cYFvKFONLWDOMWRYKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjRwOUezOkDPxE1? NXrGOIp[W0GQR1XS
SNB75 cell NHfZc2hIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHHj[W9KdmirYnn0bY9vKG:oIHj1cYFvKFOQQke1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE4xPzd|NzFOwG0> MVLTRW5ITVJ?
SR cell Mmq5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYnmXm4xUW6qaXLpeIlwdiCxZjDoeY1idiCVUjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFAxOTN5IN88US=> M4nDcnNCVkeHUh?=
SU-DHL-1 cell MmjUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGK1OFhKdmirYnn0bY9vKG:oIHj1cYFvKFOXLVTIUE0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTJwN{OzOkDPxE1? M4HNOHNCVkeHUh?=
SW684 cell MmXQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MW\Jcohq[mm2aX;uJI9nKGi3bXHuJHNYPjh2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{muNFEyKM7:TR?= NH2xSpVUSU6JRWK=
SW872 cell NGXhVYJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MX7Jcohq[mm2aX;uJI9nKGi3bXHuJHNYQDd{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD64PFY2PiEQvF2= NXPQV2FUW0GQR1XS
SW962 cell MlnVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFnRRYJKdmirYnn0bY9vKG:oIHj1cYFvKFOZOU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvPzV{MTFOwG0> MVfTRW5ITVJ?
697 cell MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVTDSYdHUW6qaXLpeIlwdiCxZjDoeY1idiB4OUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlI6QTFizszN MUXTRW5ITVJ?
8-MG-BA cell Ml\CS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2fkPGlvcGmkaYTpc44hd2ZiaIXtZY4hQC2PRz3CRUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI{NjB5OUOg{txO MlHSV2FPT0WU
A101D cell M3LTOWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYXJcohq[mm2aX;uJI9nKGi3bXHuJGEyODGGIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT64O|A{PCEQvF2= Ml62V2FPT0WU
ACN cell NEXP[o9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NH7peINKdmirYnn0bY9vKG:oIHj1cYFvKEGFTjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKxMlQ{QDdizszN MULTRW5ITVJ?
AM-38 cell NGfO[VZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4DXXGlvcGmkaYTpc44hd2ZiaIXtZY4hSU1vM{igZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME23MlI3OzJ5IN88US=> NU[1U5AxW0GQR1XS
ATN-1 cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXPtdox{UW6qaXLpeIlwdiCxZjDoeY1idiCDVF6tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI1Njd3NUWg{txO MmnwV2FPT0WU
BB30-HNC cell NYrTVIROT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEey[VZKdmirYnn0bY9vKG:oIHj1cYFvKEKEM{CtTG5EKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjJwMkWzNkDPxE1? MUTTRW5ITVJ?
BB49-HNC cell NELQRVRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NULPR3ZOUW6qaXLpeIlwdiCxZjDoeY1idiCEQkS5MWhPSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMEC3PFkh|ryP NWHzT4tlW0GQR1XS
human BC-1 cell NFHqXFhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWTUcmI2UW6qaXLpeIlwdiCxZjDoeY1idiCEQz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{46PzFyNzFOwG0> M2jVUHNCVkeHUh?=
BE-13 cell M2XzT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlXLTY5pcWKrdHnvckBw\iCqdX3hckBDTS1zMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNVQxQDIQvF2= MoXMV2FPT0WU
BL-70 cell NV3wVYF3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFjufGFKdmirYnn0bY9vKG:oIHj1cYFvKEKOLUewJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{41ODdyMzFOwG0> M3;aTHNCVkeHUh?=
BV-173 cell MojNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mk\0TY5pcWKrdHnvckBw\iCqdX3hckBDXi1zN{OgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xPE45QDV7IN88US=> NUTCUpNUW0GQR1XS
Becker cell NHvT[Y9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2nESGlvcGmkaYTpc44hd2ZiaIXtZY4hSmWla3XyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvQTV2NTFOwG0> NVjwOIZKW0GQR1XS
CAL-148 cell NILKV3BIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{LySmlvcGmkaYTpc44hd2ZiaIXtZY4hS0GOLUG0PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM2NjZ3NUeg{txO Ml\ZV2FPT0WU
TE-10 cell MmnHS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXzJcohq[mm2aX;uJI9nKGi3bXHuJHRGNTFyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkKuPFQzOyEQvF2= MXvTRW5ITVJ?
TE-12 cell NXe0UWtLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHLOfVVKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUGyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|IvPDFzNDFOwG0> Mnf3V2FPT0WU
TE-8 cell MlvLS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmGzTY5pcWKrdHnvckBw\iCqdX3hckBVTS16IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUGuOlA5QSEQvF2= NIjJeFlUSU6JRWK=
TE-9 cell NHq0eYhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWCzN41CUW6qaXLpeIlwdiCxZjDoeY1idiCWRT25JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|YvPjN6MTFOwG0> NHnr[FNUSU6JRWK=
TGW cell MXvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHvJdnBKdmirYnn0bY9vKG:oIHj1cYFvKFSJVzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKzMlM2PzdizszN MkLUV2FPT0WU
UACC-257 cell MYnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXrtfGRFUW6qaXLpeIlwdiCxZjDoeY1idiCXQVPDMVI2PyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRThwN{C2NlUh|ryP MX7TRW5ITVJ?
WSU-NHL cell NVnDWXZvT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NX;mSW13UW6qaXLpeIlwdiCxZjDoeY1idiCZU2WtUmhNKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjdwMUmwO{DPxE1? M4riW3NCVkeHUh?=
no-10 cell NYrDN2VXT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFfzcm5KdmirYnn0bY9vKG:oIHj1cYFvKG6xLUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE43Pjh2NjFOwG0> MVvTRW5ITVJ?
no-11 cell NH\TXplIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mm\OTY5pcWKrdHnvckBw\iCqdX3hckBvdy1zMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS3MlAzPjNizszN MWXTRW5ITVJ?
CAS-1 cell MWHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NELnO3dKdmirYnn0bY9vKG:oIHj1cYFvKEODUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE45PDdizszN MnTDV2FPT0WU
CCRF-CEM cell NUL0TmFzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnLPTY5pcWKrdHnvckBw\iCqdX3hckBES1KILVPFUUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvPjV|OUKg{txO M{T1fHNCVkeHUh?=
CMK cell NFHHeHBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1qxbmlvcGmkaYTpc44hd2ZiaIXtZY4hS02NIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6wNVMzOyEQvF2= NU\5XmFbW0GQR1XS
COLO-829 cell MlzZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MojmTY5pcWKrdHnvckBw\iCqdX3hckBEV0yRLUiyPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvOjR{Mk[g{txO M1j2c3NCVkeHUh?=
COR-L279 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3izOGlvcGmkaYTpc44hd2ZiaIXtZY4hS0:ULVyyO|kh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjB5M{ig{txO M3;VZXNCVkeHUh?=
CP66-MEL cell Mn76S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MniyTY5pcWKrdHnvckBw\iCqdX3hckBEWDZ4LV3FUEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM3NjV2OUeg{txO MX3TRW5ITVJ?
CRO-AP2 cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoK4TY5pcWKrdHnvckBw\iCqdX3hckBEWk9vQWCyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4{PjB6ODFOwG0> MU\TRW5ITVJ?
CTV-1 cell MlHyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkDMTY5pcWKrdHnvckBw\iCqdX3hckBEXFZvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKzMlkyPDVizszN MV;TRW5ITVJ?
Calu-6 cell M3nOWWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVjJcohq[mm2aX;uJI9nKGi3bXHuJGNidHVvNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS3MlU5PiEQvF2= M3\YRnNCVkeHUh?=
D-247MG cell MVrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHG0O2FKdmirYnn0bY9vKG:oIHj1cYFvKERvMkS3UWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjZ{OEG0JO69VQ>? M37FWHNCVkeHUh?=
D-263MG cell MnTkS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYn0TVV4UW6qaXLpeIlwdiCxZjDoeY1idiCGLUK2N21IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yOEWwPUDPxE1? MlnvV2FPT0WU
D-336MG cell NFrNZZJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoS0TY5pcWKrdHnvckBw\iCqdX3hckBFNTN|Nl3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE43Ojh3NDFOwG0> NEPxXFFUSU6JRWK=
D-392MG cell MWjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIrISJNKdmirYnn0bY9vKG:oIHj1cYFvKERvM{myUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjR|MEO5JO69VQ>? M3\acXNCVkeHUh?=
D-502MG cell NITvfI5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXLJeYN[UW6qaXLpeIlwdiCxZjDoeY1idiCGLUWwNm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:QC53M{S5NkDPxE1? MXfTRW5ITVJ?
D-542MG cell NHXCZmpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYj4O3hCUW6qaXLpeIlwdiCxZjDoeY1idiCGLUW0Nm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTJwM{G1NkDPxE1? NXT4UJlqW0GQR1XS
DB cell NH72S2pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVvJcohq[mm2aX;uJI9nKGi3bXHuJGRDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDdwMUSxO{DPxE1? NXW0epJVW0GQR1XS
DEL cell MkLWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Moe2TY5pcWKrdHnvckBw\iCqdX3hckBFTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD15LkCxPFk5KM7:TR?= M1HLRnNCVkeHUh?=
DMS-114 cell NYPGTXFJT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkizTY5pcWKrdHnvckBw\iCqdX3hckBFVVNvMUG0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFkvQDR4ODFOwG0> Mmm5V2FPT0WU
DMS-153 cell NWnZTWdFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MU\Jcohq[mm2aX;uJI9nKGi3bXHuJGROWy1zNUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Nk46QTJ|IN88US=> MmezV2FPT0WU
DOHH-2 cell Ml7oS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIHoRpFKdmirYnn0bY9vKG:oIHj1cYFvKESRSFitNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvOjJ5NkSg{txO MonPV2FPT0WU
DSH1 cell NUT0RppbT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVrJcohq[mm2aX;uJI9nKGi3bXHuJGRUUDFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD16LkSzOlI{KM7:TR?= NFHuRmtUSU6JRWK=
Daudi cell MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmnGTY5pcWKrdHnvckBw\iCqdX3hckBF[XWmaTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuNFk5ODJizszN NYDVWZJOW0GQR1XS
EC-GI-10 cell NHrJOFFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHy2ZpBKdmirYnn0bY9vKG:oIHj1cYFvKEWFLVfJMVExKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDRwMkW4PUDPxE1? MULTRW5ITVJ?
ECC4 cell MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4nDTWlvcGmkaYTpc44hd2ZiaIXtZY4hTUOFNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOyMlE5QTZizszN NXm1So1[W0GQR1XS
EM-2 cell NXHI[lg{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnnNTY5pcWKrdHnvckBw\iCqdX3hckBGVS1{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj60OVU6PCEQvF2= MoLIV2FPT0WU
ES1 cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHu2SW9KdmirYnn0bY9vKG:oIHj1cYFvKEWVMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWuOVQxQDdizszN NYP1V|M6W0GQR1XS
ES3 cell NHTMR2pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFfTUGFKdmirYnn0bY9vKG:oIHj1cYFvKEWVMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSyMlQ4OjlizszN NEe4TXZUSU6JRWK=
ES4 cell NUCyTpc{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWTye2UxUW6qaXLpeIlwdiCxZjDoeY1idiCHU{SgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOU4yQTVizszN NXTvU4tlW0GQR1XS
ES6 cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NY\yNYtXUW6qaXLpeIlwdiCxZjDoeY1idiCHU{[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlI1PzN|IN88US=> MUXTRW5ITVJ?
ES7 cell NFPnVlBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3X3dGlvcGmkaYTpc44hd2ZiaIXtZY4hTVN5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NT6yN|EzPCEQvF2= NGHEdWJUSU6JRWK=
ES8 cell MX3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2HrcmlvcGmkaYTpc44hd2ZiaIXtZY4hTVN6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD64NVkzPCEQvF2= NYm1WXZnW0GQR1XS
EW-18 cell NELOOY9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGeyUFVKdmirYnn0bY9vKG:oIHj1cYFvKEWZLUG4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvPjd3OTFOwG0> NH7aPIFUSU6JRWK=
EW-22 cell M{SzVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGOwRWVKdmirYnn0bY9vKG:oIHj1cYFvKEWZLUKyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFcvPzl2NzFOwG0> M1XzeXNCVkeHUh?=
GCIY cell NIHXU4NIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mke1TY5pcWKrdHnvckBw\iCqdX3hckBIS0m\IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OT64NFM5QSEQvF2= M4jOWHNCVkeHUh?=
GDM-1 cell NXiwT4ZlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWjJcohq[mm2aX;uJI9nKGi3bXHuJGdFVS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OD6zPVE6PiEQvF2= MVnTRW5ITVJ?
GI-1 cell NYexWI53T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoDVTY5pcWKrdHnvckBw\iCqdX3hckBIUS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6wNFUzOyEQvF2= NGjPTFJUSU6JRWK=
GI-ME-N cell NW\0NmlvT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1O1b2lvcGmkaYTpc44hd2ZiaIXtZY4hT0lvTVWtUkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODR7NUGg{txO M33wUHNCVkeHUh?=
GR-ST cell M4LadWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUjJcohq[mm2aX;uJI9nKGi3bXHuJGdTNVOWIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUOuO|kxOiEQvF2= MV7TRW5ITVJ?
GT3TKB cell NXK3NVhvT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWjJcohq[mm2aX;uJI9nKGi3bXHuJGdVO1SNQjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuOlA{QDlizszN MkDiV2FPT0WU
HAL-01 cell MnzCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFrnU|FKdmirYnn0bY9vKG:oIHj1cYFvKEiDTD2wNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvPjl5MUKg{txO MVTTRW5ITVJ?
HCC1599 cell MkjrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVvJcohq[mm2aX;uJI9nKGi3bXHuJGhESzF3OUmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zO{43ODFzIN88US=> NHzzVnVUSU6JRWK=
HCC2218 cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoTlTY5pcWKrdHnvckBw\iCqdX3hckBJS0N{MkG4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvOzh|NDFOwG0> M{PXbHNCVkeHUh?=
HD-MY-Z cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MV7Jcohq[mm2aX;uJI9nKGi3bXHuJGhFNU2\LWqgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yOU4zOTR4IN88US=> NWPsd3d5W0GQR1XS
HL-60 cell M1TtNGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M17ud2lvcGmkaYTpc44hd2ZiaIXtZY4hUExvNkCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNk4zOTF2IN88US=> NYXaOZRFW0GQR1XS
HOP-62 cell MmjIS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWTqdlBnUW6qaXLpeIlwdiCxZjDoeY1idiCKT2CtOlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOy57NUK3JO69VQ>? NHnPZnZUSU6JRWK=
HT cell NELZN5VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2H1PGlvcGmkaYTpc44hd2ZiaIXtZY4hUFRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12LkS0N|IyKM7:TR?= NVv5N|IxW0GQR1XS
HT-144 cell MnTMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NX\uNG9DUW6qaXLpeIlwdiCxZjDoeY1idiCKVD2xOFQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjlyNki2JO69VQ>? NIjRZVJUSU6JRWK=
HUTU-80 cell M3vzSGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWnRSZN7UW6qaXLpeIlwdiCxZjDoeY1idiCKVWTVMVgxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oy55OEm4OkDPxE1? M2rub3NCVkeHUh?=
IST-MEL1 cell M3vi[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmfUTY5pcWKrdHnvckBw\iCqdX3hckBKW1RvTVXMNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMzNjlyOE[g{txO NFf4dHVUSU6JRWK=
IST-SL1 cell NFvuc|VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVPlUJdWUW6qaXLpeIlwdiCxZjDoeY1idiCLU2StV2wyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oi5zN{C3PUDPxE1? NFWzTYNUSU6JRWK=
IST-SL2 cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoTnTY5pcWKrdHnvckBw\iCqdX3hckBKW1RvU1yyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{4zPjZyODFOwG0> MYXTRW5ITVJ?
K052 cell NVTIPWRCT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHrDeHRKdmirYnn0bY9vKG:oIHj1cYFvKEtyNUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlc2OzBzIN88US=> MVTTRW5ITVJ?
K5 cell NY\mSIFTT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MULJcohq[mm2aX;uJI9nKGi3bXHuJGs2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzNwNUmxOUDPxE1? MmXoV2FPT0WU
KALS-1 cell MkTmS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3PEdmlvcGmkaYTpc44hd2ZiaIXtZY4hU0GOUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlkvOzl4OTFOwG0> M{\USHNCVkeHUh?=
KARPAS-422 cell MmSyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUDRNmxNUW6qaXLpeIlwdiCxZjDoeY1idiCNQWLQRXMuPDJ{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEKuPVE1OiEQvF2= MkjqV2FPT0WU
KARPAS-45 cell MnLTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoXvTY5pcWKrdHnvckBw\iCqdX3hckBMSVKSQWOtOFUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjFzMkS3JO69VQ>? MYjTRW5ITVJ?
KE-37 cell MWDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGTBdotKdmirYnn0bY9vKG:oIHj1cYFvKEuHLUO3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PU45OzVizszN M4O0TXNCVkeHUh?=
KG-1 cell M4TocWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MV;Jcohq[mm2aX;uJI9nKGi3bXHuJGtINTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{Mz65O|U4KM7:TR?= M2HKOHNCVkeHUh?=
KGN cell NFm1W5lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmXwTY5pcWKrdHnvckBw\iCqdX3hckBMT05iY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkW2O|QzKM7:TR?= NHPnbZNUSU6JRWK=
KM12 cell NWT1UXVlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFvn[YhKdmirYnn0bY9vKG:oIHj1cYFvKEuPMUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlUzQTZ2IN88US=> NEfudnhUSU6JRWK=
KMOE-2 cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mon2TY5pcWKrdHnvckBw\iCqdX3hckBMVU:HLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNE41PTR7IN88US=> M1e3PXNCVkeHUh?=
KNS-42 cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlrLTY5pcWKrdHnvckBw\iCqdX3hckBMVlNvNEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME24MlgyQTF3IN88US=> NE\KfIVUSU6JRWK=
KNS-81-FD cell NVH3U25DT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXznSoJwUW6qaXLpeIlwdiCxZjDoeY1idiCNTmOtPFEuTkRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Nz60NlYh|ryP M3vsN3NCVkeHUh?=
KS-1 cell MlLGS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NX3aU4JjUW6qaXLpeIlwdiCxZjDoeY1idiCNUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xODR4IN88US=> Mn76V2FPT0WU
KU812 cell M1zXVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWHJcohq[mm2aX;uJI9nKGi3bXHuJGtWQDF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkOuOFg1KM7:TR?= MnTMV2FPT0WU
L-540 cell NHLOVJVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NH\LfmVKdmirYnn0bY9vKG:oIHj1cYFvKExvNUSwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlAvPzR2NTFOwG0> MX7TRW5ITVJ?
LAMA-84 cell M2XHZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYjncHhrUW6qaXLpeIlwdiCxZjDoeY1idiCOQV3BMVg1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTNwNke0NkDPxE1? Mkj6V2FPT0WU
LB1047-RCC cell M1jodmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1\SZ2lvcGmkaYTpc44hd2ZiaIXtZY4hVEJzMES3MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ6LkO4PFMh|ryP MVLTRW5ITVJ?
LB2241-RCC cell M2\0NWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1znWWlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{MkSxMXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFyLkW1N|Yh|ryP MmfLV2FPT0WU
LB2518-MEL cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVPJcohq[mm2aX;uJI9nKGi3bXHuJGxDOjVzOD3NSWwh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjdzNEm2{txO NWLlZ5JtW0GQR1XS
LB831-BLC cell MoK2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkLNTY5pcWKrdHnvckBw\iCqdX3hckBNSjh|MT3CUGMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOS5zN{K2JO69VQ>? M3r6eHNCVkeHUh?=
LB996-RCC cell NWG4V5B4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEHsWZJKdmirYnn0bY9vKG:oIHj1cYFvKEyEOUm2MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF{Lke0N|Eh|ryP NXv5OZN3W0GQR1XS
LC4-1 cell NFyxUFhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1TQV2lvcGmkaYTpc44hd2ZiaIXtZY4hVEN2LUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNk45OzRzIN88US=> NEjHPGhUSU6JRWK=
LOUCY cell NIPPfVNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkTrTY5pcWKrdHnvckBw\iCqdX3hckBNV1WFWTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNVUzPzZizszN M{jicHNCVkeHUh?=
LOXIMVI cell M4noOWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmDqTY5pcWKrdHnvckBw\iCqdX3hckBNV1iLTW\JJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|AvOjF{MjFOwG0> NUTWRZhyW0GQR1XS
LS-123 cell MlL5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3Sze2lvcGmkaYTpc44hd2ZiaIXtZY4hVFNvMUKzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|kvOjJ3ODFOwG0> MlqxV2FPT0WU
LU-134-A cell NIWzfWlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFPoPJFKdmirYnn0bY9vKG:oIHj1cYFvKEyXLUGzOE1CKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Py5zNEC2PEDPxE1? MlzLV2FPT0WU
LU-139 cell MnOwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXrJcohq[mm2aX;uJI9nKGi3bXHuJGxWNTF|OTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKyMlIyQCEQvF2= NFzEU2JUSU6JRWK=
LXF-289 cell NInyV3RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmPKTY5pcWKrdHnvckBw\iCqdX3hckBNYEZvMki5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVcvPDN3Md88US=> M2noZnNCVkeHUh?=
MC116 cell M4K5NGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYjJcohq[mm2aX;uJI9nKGi3bXHuJG1EOTF4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEWuNFg1OSEQvF2= MYjTRW5ITVJ?
MDA-MB-134-VI cell MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHW0Z4lKdmirYnn0bY9vKG:oIHj1cYFvKE2GQT3NRk0yOzRvVlmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zPU4zPDh4IN88US=> NELwPG5USU6JRWK=
MFH-ino cell MoO1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWjINnBmUW6qaXLpeIlwdiCxZjDoeY1idiCPRlitbY5wKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC54NEO4N{DPxE1? Ml;TV2FPT0WU
MHH-NB-11 cell MlLjS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlXOTY5pcWKrdHnvckBw\iCqdX3hckBOUEhvTlKtNVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB4Nkmg{txO NVHnSWE{W0GQR1XS
ML-2 cell NXnReVcxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUnJcohq[mm2aX;uJI9nKGi3bXHuJG1NNTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|LkSwN|A1KM7:TR?= NHvlVG9USU6JRWK=
MOLT-13 cell MlS4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkPxTY5pcWKrdHnvckBw\iCqdX3hckBOV0yWLUGzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE41OzZ3MzFOwG0> MmXvV2FPT0WU
MOLT-16 cell NHX2OmRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnnpTY5pcWKrdHnvckBw\iCqdX3hckBOV0yWLUG2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE4yOTF4MzFOwG0> MXrTRW5ITVJ?
MOLT-4 cell M3q5fWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MoTnTY5pcWKrdHnvckBw\iCqdX3hckBOV0yWLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xOE41OTJ2IN88US=> MmTUV2FPT0WU
MPP-89 cell NFLtTXNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXTUN3BRUW6qaXLpeIlwdiCxZjDoeY1idiCPUGCtPFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjJ3OUKyJO69VQ>? NEXFVXFUSU6JRWK=
MRK-nu-1 cell MlP6S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M365[GlvcGmkaYTpc44hd2ZiaIXtZY4hVVKNLX71MVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjV5NUeyJO69VQ>? MU\TRW5ITVJ?
MSTO-211H cell NIjsepRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3fTbGlvcGmkaYTpc44hd2ZiaIXtZY4hVVOWTz2yNVFJKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTJwOE[5JO69VQ>? NUjPN4lNW0GQR1XS
MV-4-11 cell NYn5fGdDT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{TNSWlvcGmkaYTpc44hd2ZiaIXtZY4hVVZvND2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOTN7MUWg{txO NVXReFZrW0GQR1XS
NALM-6 cell M2i2PWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIHSe5dKdmirYnn0bY9vKG:oIHj1cYFvKE6DTF2tOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvPTZzMEmg{txO MmXTV2FPT0WU
NB1 cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVPJcohq[mm2aX;uJI9nKGi3bXHuJG5DOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTNwOESzOlkh|ryP MVfTRW5ITVJ?
NB10 cell NXz0VHR5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlTnTY5pcWKrdHnvckBw\iCqdX3hckBPSjFyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6xN|kyPSEQvF2= NFPDZWFUSU6JRWK=
NB12 cell NVTQTGJIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NX\WN|RmUW6qaXLpeIlwdiCxZjDoeY1idiCQQkGyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVYvPTZ3NjFOwG0> MULTRW5ITVJ?
NB13 cell Mn3VS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXvoUZNrUW6qaXLpeIlwdiCxZjDoeY1idiCQQkGzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4{OTJ5ODFOwG0> NF3Ye|BUSU6JRWK=
NB17 cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkfTTY5pcWKrdHnvckBw\iCqdX3hckBPSjF5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz61PFA2OSEQvF2= M4TC[HNCVkeHUh?=
NB6 cell M{nYW2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFXHN2ZKdmirYnn0bY9vKG:oIHj1cYFvKE6ENjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuOVkyOTRizszN NYDXclBZW0GQR1XS
NCCIT cell MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYe1OlBNUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1PJWEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQyNjh2NUOg{txO M4\tSHNCVkeHUh?=
NCI-H1155 cell MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MorhTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEGxOVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPC5|NEC4JO69VQ>? NH3BTIFUSU6JRWK=
NCI-H1304 cell M13heWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnvCTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEGzNFQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOS56OUiyJO69VQ>? MlnnV2FPT0WU
NCI-H1355 cell MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M325R2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixN|U2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC57NEGxJO69VQ>? M4T4enNCVkeHUh?=
NCI-H1395 cell MmnKS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUTncopwUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE{QTViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{Mj64O|k2KM7:TR?= NF3Ec2RUSU6JRWK=
NCI-H1417 cell NYftZlhQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYnJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUSxO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUvPjd3MkKg{txO MkT5V2FPT0WU
NCI-H1436 cell MlL2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1X0d2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOFM3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oy56NEGwNUDPxE1? MkPVV2FPT0WU
NTERA-S-cl-D1 cell NHS3ToFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnvqTY5pcWKrdHnvckBw\iCqdX3hckBPXEWUQT3TMYNtNURzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUKuPFk{PSEQvF2= NHjqZpZUSU6JRWK=
JiyoyeP-2003 cell NUXzRWRpT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnjkTY5pcWKrdHnvckBw\iCqdX3hckBLcXmxeXXQMVIxODNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Nj62Nlg1KM7:TR?= M{\xUHNCVkeHUh?=

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体内研究 自发性高血压大鼠口服GSK269962A将降低体循环血压,血压的减少非常迅速并显著。在口服给药后约2小时,其降血压作用达到峰值。血压的减少伴随着急性、剂量依赖性的心率增加,这可能是压力反射机制的激活[1]。用10 mg/kg的GSK 269962抑制ROCK在大鼠内能依次地引起排尿量、排尿后残余尿、容量阈值、泌尿效率、ICI(intercontraction interval)、膀胱顺应性、VTNVC的升高,而对心率、收缩压、平均血压、舒张压没有影响[2]

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

细胞实验:[1]
+ 展开
  • Cell lines: 平滑肌细胞
  • Concentrations: 3 μM
  • Incubation Time: 150 min
  • Method: 对人类平滑肌细胞进行血清饥饿处理(细胞于盖玻片上生长,达到50%融合时,血清饥饿处理过夜),用AngⅡ(100 nM)对其进行刺激2小时。在刺激前30分钟,加入ROCK抑制剂(3 μM SB-772077-B或GSK269962A),刺激后将细胞进行固定,用鬼笔环肽对肌动蛋白进行染色。
    (Only for Reference)
动物实验:[2]
+ 展开
  • Animal Models: Wistar雌性大鼠
  • Formulation: 生理盐水
  • Dosages: 5 或 10 mg/kg
  • Administration: 动脉注射
    (Only for Reference)

溶解度 (25°C)

体外 DMSO 100 mg/mL (164.72 mM)
Ethanol 6 mg/mL (9.88 mM)
Water Insoluble

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 607.06
化学式

C29H30N8O5.HCl

CAS号 850664-21-0(free base)
稳定性 powder
in solvent
别名 GSK269962B, GSK269962, GSK 269962

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

技术支持

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操作手册

如果有其他问题,请给我们留言。

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ROCK Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID