NU7441 (KU-57788)

For research use only. Not for use in humans.

目录号:S2638

NU7441 (KU-57788) Chemical Structure

Molecular Weight(MW): 413.49

NU7441 (KU-57788)是一种高度有效的,选择性DNA-PK抑制剂,在无细胞试验中IC50为14 nM,也会抑制PI3K,IC50为5 μM。它可降低NHEJ的频率,而增强Cas9介导DNA剪接后发生的同源重组修复率。

规格 价格 库存 购买数量  
RMB 565.91 现货
RMB 974.57 现货
RMB 3040.41 现货
RMB 7928.18 现货
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客户使用Selleck生产的NU7441 (KU-57788)发表文献94篇:

产品安全说明书

DNA-PK抑制剂选择性比较

生物活性

产品描述 NU7441 (KU-57788)是一种高度有效的,选择性DNA-PK抑制剂,在无细胞试验中IC50为14 nM,也会抑制PI3K,IC50为5 μM。它可降低NHEJ的频率,而增强Cas9介导DNA剪接后发生的同源重组修复率。
靶点
DNA-PK [1]
(Cell-free assay)
14 nM
体外研究

NU7441抑制DNA依赖性蛋白激酶 (DNA-PK) 比抑制其他PI3K相关激酶 (PIKK)家族成员选择性高,IC50 为14 nM。[1] 电离辐射诱导或Etoposide诱导 DNA 损伤后,1 μM NU7441提高γH2AX病灶的持久性。NU7441 浓度为 0.5 μM 或 1 μM时,作用于SW620 和 LoVo细胞,显著提高电离辐射,Etoposide, 和 Doxorubicin 诱导的G2-M累积增多。[2] NU7441浓度为1 μM时,引起 Doxorubicin和电离辐射诱导的DNA双链断裂的持久性,也稍微降低同源重组活性 DNA-PK充足的 M059-Fus-1和 DNA-PK缺陷的 M059 J人类肿瘤细胞。[3] NU7441浓度为 10 μM 时,作用于缺乏和表达polη的细胞,抑制UV诱导 RPA p34过度磷酸化。[4] NU7441 浓度为1 μM时,作用于慢性淋巴细胞性白血病细胞。提高Fludarabine诱导的γH2AX病灶水平,也相应地降低Fludarabine诱导的细胞死亡。[5] NU7441浓度为 1 μM时,作用于慢性淋巴细胞性白血病细胞,抑制Mitoxantrone诱导的DNA-PKcs自磷酸化和修复。[6]它可降低NHEJ的频率,而增强Cas9介导DNA剪接后发生的同源重组修复率 [7]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1770 NVvBfoFOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NED2VYlKSzVyPUCuNFIyPDNizszN NXnaeFBYW0GQR1XS
A172 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYO1e|ZoUUN3ME2wMlE2OzF4IN88US=> M3flfXNCVkeHUh?=
NCI-H526 Mor2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHPlU2lKSzVyPUCuNlg1ODdizszN NYTqcoRGW0GQR1XS
HDLM-2 Mn7HS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVvJR|UxRTBwM{KzOFUh|ryP MWnTRW5ITVJ?
HuO-3N1 Mm\OS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHzmSZdKSzVyPUCuOFY3OzZizszN MXvTRW5ITVJ?
NCI-SNU-1 M3HtOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NU\D[FhnUUN3ME2wMlYxQTl2IN88US=> NGj4bYpUSU6JRWK=
SK-N-AS NVH1VHhtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF3OfWRKSzVyPUCuOlIzOTZizszN Mlf0V2FPT0WU
LoVo MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWjJR|UxRTBwOE[3OFkh|ryP NEXzSVlUSU6JRWK=
LAMA-84 MnjES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHrXU4RKSzVyPUCuPVg5OzNizszN MnjUV2FPT0WU
CTB-1 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWHhd2hrUUN3ME2xMlEyPTR4IN88US=> MVLTRW5ITVJ?
KP-N-YS M2fKb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NISwWG5KSzVyPUGuNVQzOzFizszN Mn\6V2FPT0WU
HH NFuzc5ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml33TWM2OD1zLkG4NFk{KM7:TR?= MljPV2FPT0WU
CHL-1 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXPJR|UxRTFwMkGzOlgh|ryP NGD0SmtUSU6JRWK=
NB7 NXj2[|dnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWXJR|UxRTFwMkS3OFUh|ryP NV;MXZFqW0GQR1XS
HL-60 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEXiOZNKSzVyPUGuN|gyQSEQvF2= NUPjcYNsW0GQR1XS
639-V NUj5RVhPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3XqO2lEPTB;MT60OFEzQCEQvF2= NX3RUJJqW0GQR1XS
NCI-H1793 M3T5Wmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3PseGlEPTB;MT60OVg1KM7:TR?= MmnJV2FPT0WU
NEC8 M{mzRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mln2TWM2OD1zLkW1N|Uh|ryP NHfIWVRUSU6JRWK=
PA-1 NXjlcW15T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1H3bGlEPTB;MT61PFI6PCEQvF2= M3SwUHNCVkeHUh?=
D-423MG MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYDJR|UxRTFwNkmzOlEh|ryP NWfSTokxW0GQR1XS
NCI-H292 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmrUTWM2OD1zLke0NFE{KM7:TR?= M2rye3NCVkeHUh?=
SK-MEL-1 MmT2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NITib3ZKSzVyPUGuO|k1PzlizszN NHq5cYlUSU6JRWK=
LB2241-RCC MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlHsTWM2OD1{LkG0NVQ3KM7:TR?= Mkf2V2FPT0WU
SK-MEL-3 NWXGd|RGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3rwZ2lEPTB;Mj6xOlQ6KM7:TR?= M3L1PHNCVkeHUh?=
MHH-PREB-1 M2excmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUHJR|UxRTJwMU[2NFkh|ryP NH\5XZlUSU6JRWK=
BFTC-905 M3zCVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{PDTWlEPTB;Mj6xOlY5PyEQvF2= NF7N[mpUSU6JRWK=
Ramos-2G6-4C10 M4Lx[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlfETWM2OD1{LkG5PVA6KM7:TR?= Mo\SV2FPT0WU
G-361 M1XSR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWDqOlVTUUN3ME2yMlIyPjhizszN NYTU[YdjW0GQR1XS
MOLT-4 NUnNVo43T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1[0T2lEPTB;Mj6yNVg5QCEQvF2= NGS1eWtUSU6JRWK=
DEL NX34OndvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHroN|NKSzVyPUKuN|U2PjRizszN MWnTRW5ITVJ?
MV-4-11 NEPVd2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4jjOWlEPTB;Mj6zO|M6KM7:TR?= MXnTRW5ITVJ?
SK-NEP-1 MoPDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYDJR|UxRTJwM{i3PFMh|ryP M1;0S3NCVkeHUh?=
RS4-11 MlnLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1PibWlEPTB;Mj61OlAzOyEQvF2= M37LS3NCVkeHUh?=
HuH-7 NWjR[3pYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4SzW2lEPTB;Mj61OlcxOiEQvF2= NYjP[G9KW0GQR1XS
A101D MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1Pv[mlEPTB;Mj62NVM{QCEQvF2= NIDkWI5USU6JRWK=
KG-1 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWrLVXNzUUN3ME2yMlY4QTJ2IN88US=> MWDTRW5ITVJ?
KALS-1 NHjTbphIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHK0N5pKSzVyPUKuOlk3OzNizszN NIDKZ2NUSU6JRWK=
VMRC-RCZ MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoLnTWM2OD1{Lke3N|I5KM7:TR?= NUjrPHZ2W0GQR1XS
SK-UT-1 MlvoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVXB[VFKUUN3ME2zMlE2OzFizszN MoHiV2FPT0WU
SW962 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NELPNXJKSzVyPUOuNlA{PTJizszN MWXTRW5ITVJ?
DBTRG-05MG Ml\MS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWiwcnRUUUN3ME2zMlI5ODh3IN88US=> MWrTRW5ITVJ?
PANC-08-13 NVPrdVE1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4H2RmlEPTB;Mz60NVI4QCEQvF2= MY\TRW5ITVJ?
QIMR-WIL NF\vS41Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MorkTWM2OD1|LkSxN|QyKM7:TR?= NXPLNmpTW0GQR1XS
SK-MEL-30 M2rNV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFLDXYpKSzVyPUOuOFI2QThizszN NIHQ[WdUSU6JRWK=
697 M4S1OGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M13CWWlEPTB;Mz60OFk6OyEQvF2= Ml3CV2FPT0WU
NY NIL0ZWlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYrJN29qUUN3ME2zMlQ2ODJ{IN88US=> NILqb4ZUSU6JRWK=
ES7 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHThXpdKSzVyPUOuOFY4OjlizszN NH2zeJVUSU6JRWK=
JVM-3 M3rQZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NU[5T4huUUN3ME2zMlQ5ODd5IN88US=> NF7TWFNUSU6JRWK=
U031 NXS4fod1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHzFUHhKSzVyPUOuOVk{PjhizszN MljXV2FPT0WU
BHT-101 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIf4NmJKSzVyPUOuOVk6QDVizszN NWW4PG1HW0GQR1XS
8305C Mn:1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVHJR|UxRTNwNkG3N|Yh|ryP MXLTRW5ITVJ?
MG-63 NYTIN5diT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1fse2lEPTB;Mz62NlY4PiEQvF2= MkHRV2FPT0WU
NOS-1 NV3IfWJ1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVzJR|UxRTNwNkWzNVIh|ryP MliyV2FPT0WU
YH-13 M3rKZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGXr[45KSzVyPUOuPFcyQDlizszN NUPNUWZiW0GQR1XS
LXF-289 NXPMOlVQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVPzTmxHUUN3ME2zMlkyODRzIN88US=> MkLvV2FPT0WU
GOTO NFTqfGJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXLJR|UxRTNwOUG0PUDPxE1? NWr4RY1{W0GQR1XS
EKVX M4\CeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3rQW2lEPTB;ND6yNlUzPCEQvF2= NHqxZ3lUSU6JRWK=
CAL-51 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEXaXYdKSzVyPUSuNlQ5PTRizszN NIPsUGNUSU6JRWK=
AN3-CA NUCxeoRXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmnNTWM2OD12LkK1PFE{KM7:TR?= NEjXeZFUSU6JRWK=
IA-LM MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVjOWldQUUN3ME20MlI4QTN3IN88US=> MknTV2FPT0WU
KU-19-19 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV3JR|UxRTRwM{K5NlEh|ryP MX7TRW5ITVJ?
A704 M4nWdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkfLTWM2OD12LkSwPFg5KM7:TR?= NHv2VGtUSU6JRWK=
RH-18 M2nFR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXPJR|UxRTRwNES5OVMh|ryP MUHTRW5ITVJ?
IST-MEL1 NVfqV3l7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4j2XGlEPTB;ND61PFI3OyEQvF2= NY\ufndHW0GQR1XS
LU-134-A MoTBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTRwNUm2PFUh|ryP NH3kTllUSU6JRWK=
SF126 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEnqVFlKSzVyPUSuOlA4OTVizszN MXjTRW5ITVJ?
EFO-27 M3PqXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF[1WlBKSzVyPUSuOlY2OjVizszN MVnTRW5ITVJ?
SN12C NFrLNoRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFzJcXRKSzVyPUSuO|E5QThizszN NG\HOmVUSU6JRWK=
L-363 NHHLdWRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3K2VmlEPTB;ND63O|EyPiEQvF2= NUPB[FRQW0GQR1XS
MEL-HO NGrhZ4VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlvmTWM2OD12Lke3PVg6KM7:TR?= M2G0V3NCVkeHUh?=
TYK-nu M4DVemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlnjTWM2OD12LkiwNVI5KM7:TR?= NGfoNndUSU6JRWK=
MDA-MB-415 NF7LZo5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHHifVlKSzVyPUWuNFA{OTRizszN NE\iUohUSU6JRWK=
HCC70 NUHxfII3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHWwSpZKSzVyPUWuNFM6OzlizszN NWjDdGNrW0GQR1XS
IGROV-1 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn3ETWM2OD13LkK1NlkzKM7:TR?= NITC[GxUSU6JRWK=
NCI-H1355 NVfy[pM3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYTUUYVLUUN3ME21MlI6PiEQvF2= M1rKfnNCVkeHUh?=
23132-87 NV61UYFHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYrMZnIzUUN3ME21MlMzODJ2IN88US=> M132XXNCVkeHUh?=
NB69 MnXtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4\qZWlEPTB;NT6zNlQzKM7:TR?= NXLyXY5IW0GQR1XS
HSC-2 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnfPTWM2OD13LkSxO|c{KM7:TR?= M{fZZnNCVkeHUh?=
KYSE-410 NGrwV2hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUjJR|UxRTVwNEe2N|Yh|ryP MlvVV2FPT0WU
GCIY NGLZeIpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlG0TWM2OD13LkWxN|c5KM7:TR?= MYPTRW5ITVJ?
A427 NVvo[W1vT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYXEeGtoUUN3ME21MlU{PjZzIN88US=> M3PxTHNCVkeHUh?=
ChaGo-K-1 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX7JR|UxRTVwNU[1PVkh|ryP M2nTfXNCVkeHUh?=
PFSK-1 NFraOJJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYfDcZVJUUN3ME21MlYzOTl2IN88US=> MX3TRW5ITVJ?
MLMA NF3wUmtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkHvTWM2OD13LkizOlA3KM7:TR?= M3zoR3NCVkeHUh?=
RVH-421 MlHnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUjLcJJLUUN3ME22MlA4OzN6IN88US=> MWPTRW5ITVJ?
LB1047-RCC M2fOXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYfJR|UxRTZwMUe1NlIh|ryP M2r0WHNCVkeHUh?=
MHH-NB-11 NETsZ4xIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mo\3TWM2OD14LkOyO|IyKM7:TR?= MULTRW5ITVJ?
J-RT3-T3-5 MoCxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmKzTWM2OD14Lk[zNlkyKM7:TR?= NVr1fYdVW0GQR1XS
UM-UC-3 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGPpb|dKSzVyPU[uOlQ{OzRizszN M3nFOnNCVkeHUh?=
IST-SL1 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{jkcGlEPTB;Nj62PVM3QSEQvF2= NHvSRppUSU6JRWK=
NB14 NYO2Oo55T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4nHO2lEPTB;Nj63PVc3OSEQvF2= NUD5[4RjW0GQR1XS
NBsusSR NITqfVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWLFbGk6UUN3ME22MlgzPTB{IN88US=> MoLlV2FPT0WU
D-263MG M1;HTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmLXTWM2OD14LkmxNFY5KM7:TR?= NVTFPYpuW0GQR1XS
NCI-H2347 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVLJR|UxRTZwOUOyNVMh|ryP MWHTRW5ITVJ?
ES8 NGG1NllIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTZwOUe1PFgh|ryP NH;leINUSU6JRWK=
786-0 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX3JR|UxRTdwMEm3PFYh|ryP NVK1WZlrW0GQR1XS
EPLC-272H MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVHJR|UxRTdwMU[yOFYh|ryP MmnsV2FPT0WU
CAPAN-1 NUPiSYxIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFn5e3JKSzVyPUeuNlQ{PTlizszN MUHTRW5ITVJ?
NCI-H82 Ml7sS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmL6TWM2OD15LkK2OlU6KM7:TR?= MU\TRW5ITVJ?
G-402 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYD1XZRoUUN3ME23MlMxODVzIN88US=> NHrac4RUSU6JRWK=
SW982 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1LuR2lEPTB;Nz6zNFIxOyEQvF2= MXzTRW5ITVJ?
OVCAR-4 NVvpRVRxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYfabYxOUUN3ME23MlMyOzJ6IN88US=> MXXTRW5ITVJ?
KARPAS-299 NGDMbFZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1;ZWWlEPTB;Nz6zNlYzOiEQvF2= NYTTXXBWW0GQR1XS
MIA-PaCa-2 NVnGS|JqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF7nZWRKSzVyPUeuN|Y5OjNizszN NIjVS2hUSU6JRWK=
AU565 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoWwTWM2OD15LkW5PFM{KM7:TR?= M3y0b3NCVkeHUh?=
GAMG NWPvUpJtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkPwTWM2OD15Lk[0NVMyKM7:TR?= MXHTRW5ITVJ?
HuO9 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn3rTWM2OD15LkexO|Q{KM7:TR?= MkLSV2FPT0WU
ACN MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmTGTWM2OD15Lke0N|Mh|ryP Mk\pV2FPT0WU
RO82-W-1 NYXEcmJzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHPnVlFKSzVyPUeuO|Q2OzNizszN M{m2b3NCVkeHUh?=
NKM-1 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXfUcGpQUUN3ME23Mlc1QTV3IN88US=> NH\6cpVUSU6JRWK=
CAL-12T NGPh[25Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1fQRWlEPTB;Nz65OFM2OiEQvF2= M3XIT3NCVkeHUh?=
FADU MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWrMTG1vUUN3ME24MlA{PjV2IN88US=> NFq4PZpUSU6JRWK=
NCI-H28 NVrIO4ZkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV7JR|UxRThwMU[5OlIh|ryP Moe2V2FPT0WU
LCLC-97TM1 NEfDUWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlnrTWM2OD16LkKxNVIzKM7:TR?= NFrXWXNUSU6JRWK=
CHP-134 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkW0TWM2OD16LkK0NVg2KM7:TR?= NYThTYRSW0GQR1XS
HT-1080 M4f0WWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnTUTWM2OD16LkK1NFk{KM7:TR?= MXHTRW5ITVJ?
PC-3 MlXoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M13DcWlEPTB;OD6yO|M6OiEQvF2= MoTQV2FPT0WU
SNU-449 M{LCbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mmr1TWM2OD16LkK3PVMh|ryP NXfrT|BnW0GQR1XS
VA-ES-BJ Mmq1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2\BdmlEPTB;OD6zOFY5PiEQvF2= NFLDdoxUSU6JRWK=
HT M1\H[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH[0VHpKSzVyPUiuN|Y1QSEQvF2= M4rLcnNCVkeHUh?=
HOS MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoD0TWM2OD16LkO3OVg6KM7:TR?= NX3pUZVrW0GQR1XS
KNS-62 NEnQdYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX;JR|UxRThwM{e3OlIh|ryP MXTTRW5ITVJ?
OAW-42 NYHjcY1xT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXTJR|UxRThwOUW5OlQh|ryP M{HsbnNCVkeHUh?=
A549 NUTOVpN7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVnJR|UxRTlwMEm2NVIh|ryP NH62SIFUSU6JRWK=
CAKI-1 Ml7ES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXXLOFBrUUN3ME25MlE3PjFizszN MYXTRW5ITVJ?
HCC1937 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3fO[2lEPTB;OT62PVg3PSEQvF2= MUTTRW5ITVJ?
GI-ME-N NXLpcIVST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2\Ob2lEPTB;OT63NFE{PyEQvF2= MmHBV2FPT0WU
DU-4475 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWCwem5wUUN3ME25Mlk3QTN7IN88US=> NF\xNndUSU6JRWK=
EM-2 MlznS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUnJR|UxRTFyLkK0NlYh|ryP NEfWSGNUSU6JRWK=
NCI-H1755 MnP3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVfJR|UxRTFyLkK0Nlgh|ryP Ml;SV2FPT0WU
NCI-H1437 NXP5e2czT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXzJR|UxRTFyLkW3NlUh|ryP M37NbHNCVkeHUh?=
VM-CUB-1 NG\jOZZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHO1TXlKSzVyPUGwMlYyPjRizszN NFH5PHVUSU6JRWK=
A2058 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoH0TWM2OD1zMD62OFA1KM7:TR?= NF\JTpFUSU6JRWK=
BPH-1 NYTKXlBkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH7LZYtKSzVyPUGwMlcyPDVizszN Mn2xV2FPT0WU
NB5 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYnR[GZPUUN3ME2xNE44PTV7IN88US=> NEXPVpJUSU6JRWK=
G-401 M2XkWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVvJR|UxRTFyLke2NlYh|ryP MmK4V2FPT0WU
CAL-72 M1PV[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXjJR|UxRTFyLkiwPVQh|ryP MoCzV2FPT0WU
SK-MEL-28 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn;CTWM2OD1zMD64NlAzKM7:TR?= NF:5[3dUSU6JRWK=
C32 NW\WV|NWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH3FbnlKSzVyPUGwMlg{PDdizszN NFjnTpZUSU6JRWK=
NCI-H1155 NIfhWXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mo\BTWM2OD1zMD64N|c3KM7:TR?= MVfTRW5ITVJ?
BB49-HNC MmnsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEGzcm1KSzVyPUGwMlg2QDZizszN MYPTRW5ITVJ?
GMS-10 M3S4d2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWW0ZodDUUN3ME2xNE45QTdzIN88US=> MoX3V2FPT0WU
K5 M2nPfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmLLTWM2OD1zMD65NFcyKM7:TR?= M3;s[XNCVkeHUh?=
OS-RC-2 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXrMSGxPUUN3ME2xNU4xPTV7IN88US=> NGjmW4pUSU6JRWK=
HTC-C3 NHfnXJNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGjIUHZKSzVyPUGxMlA4OTRizszN M3f6NnNCVkeHUh?=
LB996-RCC NHXtRVVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4HaPWlEPTB;MUGuNFczOyEQvF2= MmfUV2FPT0WU
NCI-H1563 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGi3fpdKSzVyPUGxMlExOTFizszN MV7TRW5ITVJ?
CAL-54 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX6z[Y1iUUN3ME2xNU41QDFzIN88US=> NI\KT3dUSU6JRWK=
WM-115 NWXVPHhbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{Hr[GlEPTB;MUGuOlgzPCEQvF2= MkP4V2FPT0WU
COLO-684 NXjKTXQ{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUfOfo5{UUN3ME2xNU44OjZ5IN88US=> MWjTRW5ITVJ?
HOP-62 M{jSe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWjJR|UxRTFzLke1NFgh|ryP MXzTRW5ITVJ?
NCI-H650 M4rJNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoS3TWM2OD1zMT64PVYyKM7:TR?= NX7hcJB3W0GQR1XS
TE-11 NGfIWndIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnTwTWM2OD1zMT65N|E2KM7:TR?= NXHITGMxW0GQR1XS
COLO-679 NHSxSJdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3rLPWlEPTB;MUGuPVQ3KM7:TR?= NV;KOWJQW0GQR1XS
FTC-133 NGnCZoFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVLaTmc{UUN3ME2xNk4xODd4IN88US=> MWXTRW5ITVJ?
D-283MED MkHHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2ryTmlEPTB;MUKuNFU3QSEQvF2= Mom0V2FPT0WU
SK-PN-DW NHnKXZFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFTSbVlKSzVyPUGyMlE6ODJizszN Mn3KV2FPT0WU
BALL-1 MmLCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{fJWGlEPTB;MUKuNlY3OiEQvF2= M2e1[HNCVkeHUh?=
GT3TKB MkD1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX3TWZVVUUN3ME2xNk4{ODd2IN88US=> Mn;KV2FPT0WU
HOP-92 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUHJR|UxRTF{LkWyN|Mh|ryP NUSzdnhJW0GQR1XS
M14 MnHkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXn0NIVuUUN3ME2xN{4xOzN3IN88US=> MVjTRW5ITVJ?
SKG-IIIa MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn\PTWM2OD1zMz6wOVU1KM7:TR?= NEH6c5ZUSU6JRWK=
Becker MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV;JR|UxRTF|LkC1PEDPxE1? NVvF[pdiW0GQR1XS
ES5 NYnFbGRVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFzXXZJKSzVyPUGzMlE{PTZizszN NV:5doRYW0GQR1XS
NCI-H2030 MoTHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXnhTItZUUN3ME2xN{4zODZ{IN88US=> MU\TRW5ITVJ?
SNU-423 MmHnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{LWd2lEPTB;MUOuN|gyKM7:TR?= MY\TRW5ITVJ?
CP50-MEL-B M{KyOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkXNTWM2OD1zMz62NlMzKM7:TR?= Mle0V2FPT0WU
NCI-H1092 NVS0WVRbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV7JR|UxRTF|Lke0O|Uh|ryP MV3TRW5ITVJ?
8-MG-BA NWiybG5uT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NY\3cld4UUN3ME2xN{44PTF|IN88US=> M2nhPHNCVkeHUh?=
CAL-27 Ml3LS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1fnOGlEPTB;MUSuNFczPyEQvF2= M3zDc3NCVkeHUh?=
AGS MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkTlTWM2OD1zND6xN|E6KM7:TR?= NHHhe4RUSU6JRWK=
MZ2-MEL M3OzXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYPmNWRJUUN3ME2xOE4yPDh6IN88US=> MXHTRW5ITVJ?
BFTC-909 NVfNR5hST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWTJboVHUUN3ME2xOE42ODV3IN88US=> MVjTRW5ITVJ?
D-566MG NU\wXHBUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NU\C[pNZUUN3ME2xOE44PzB4IN88US=> MX;TRW5ITVJ?
MZ7-mel MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHvn[Y5KSzVyPUG1MlExPjdizszN MoXlV2FPT0WU
TE-5 M3vSN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnnZTWM2OD1zNT6yN|M{KM7:TR?= NIPTO2ZUSU6JRWK=
647-V NFvWRlJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEe4UpdKSzVyPUG1MlI4ODVizszN M1;HWXNCVkeHUh?=
DMS-114 M4\xR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2PSN2lEPTB;MUWuN|I6OSEQvF2= NF\4VmRUSU6JRWK=
ME-180 NUjycodGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGT1b4NKSzVyPUG1MlQ4QDNizszN NVLLdWZrW0GQR1XS
MS-1 M1nvTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4XjWmlEPTB;MUWuOVYzOyEQvF2= M2PP[3NCVkeHUh?=
NUGC-3 NV;OXVBRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEjt[HBKSzVyPUG1MlYzPDVizszN NX;xOVl7W0GQR1XS
GB-1 M3:3c2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn7tTWM2OD1zNT62OFM4KM7:TR?= NVnqNpZ3W0GQR1XS
LOXIMVI NF3hU4pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnrITWM2OD1zNT64PVE6KM7:TR?= M{[2RXNCVkeHUh?=
NCI-H1304 NEnidmVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUnIOXc2UUN3ME2xOU45QTJ6IN88US=> MUXTRW5ITVJ?
KURAMOCHI MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{fZcWlEPTB;MUWuPVcyKM7:TR?= MmPWV2FPT0WU
SW1783 NV6wdG12T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWfsfVVWUUN3ME2xOk4xQTl|IN88US=> NYnB[HBVW0GQR1XS
EGI-1 MoPHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEjTOZVKSzVyPUG2MlU{PjVizszN NIDJWW5USU6JRWK=
KGN M{DJRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXPJR|UxRTF4LkW1PFYh|ryP NHm1ZY9USU6JRWK=
PANC-03-27 M3TlbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3vtUmlEPTB;MU[uO|Y3OiEQvF2= MYDTRW5ITVJ?
RH-1 M{HNNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHWyV3NKSzVyPUG2MlgzPSEQvF2= MUPTRW5ITVJ?
HT-1376 NYnl[VdCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MY\JR|UxRTF4Lki0OFYh|ryP M1jhSHNCVkeHUh?=
ZR-75-30 NYHWdVUyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVvJR|UxRTF4LkmzOlEh|ryP M3rCbnNCVkeHUh?=
TI-73 Mm\DS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEjPdYVKSzVyPUG2Mlk1ODhizszN MmXPV2FPT0WU
TK10 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{CwN2lEPTB;MUeuNFA4QSEQvF2= NUP6b|R4W0GQR1XS
SW684 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYrJR|UxRTF5LkCxOVQh|ryP NYqzN5pXW0GQR1XS
RPMI-8866 M1Kx[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXnN[nJ6UUN3ME2xO{4xPjl7IN88US=> MV\TRW5ITVJ?
LNCaP-Clone-FGC NIfJZmZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3qwW2lEPTB;MUeuOVIxOSEQvF2= MVnTRW5ITVJ?
NCI-H2291 NFrubFhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFPEcZlKSzVyPUG4MlQ{PDVizszN MUDTRW5ITVJ?
T47D NUHXcWtZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUfDN2RrUUN3ME2xPE41QDhizszN MUjTRW5ITVJ?
A204 M4rsTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1TzUGlEPTB;MUiuOVQ2OiEQvF2= M2rMcHNCVkeHUh?=
HT-144 NFiyNJZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXrJR|UxRTF6Lke0Nlch|ryP MYLTRW5ITVJ?
MDA-MB-361 MmDIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXvyWJROUUN3ME2xPU4xPzF2IN88US=> Ml;WV2FPT0WU
HCC1806 NHTDWWJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mnn3TWM2OD1zOT6xOVkyKM7:TR?= NYjWZWR{W0GQR1XS
NCI-H596 MknwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYTJR|UxRTF7Lk[zPVEh|ryP NHnOXldUSU6JRWK=
K-562 MlLiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVzRT5JnUUN3ME2xPU45QTJ4IN88US=> M2jsbnNCVkeHUh?=
D-336MG NE\QV29Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mm\0TWM2OD1zOT65N|IzKM7:TR?= NI\ndlZUSU6JRWK=
SK-MEL-2 NVO4[lRMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1nodmlEPTB;MkCuNVU2QSEQvF2= NYDBNmg5W0GQR1XS
HEC-1 NVW5eWN6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWTKdJR[UUN3ME2yNE41QTd6IN88US=> M4C2NXNCVkeHUh?=
EW-13 NUSy[HFyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVnPW3JzUUN3ME2yNE42PDR|IN88US=> M360OnNCVkeHUh?=
Hs-578-T MoO5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mo\iTWM2OD1{MD61OVg{KM7:TR?= NU\CbGZMW0GQR1XS
SJSA-1 NVfmNVJXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWrJR|UxRTJyLkW2PFgh|ryP NHzMeINUSU6JRWK=
RCC10RGB M2f5eWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXfPZmV{UUN3ME2yNE43PzF7IN88US=> M2jyXHNCVkeHUh?=
LAN-6 NEfy[W5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1PjU2lEPTB;MkGuNFM6PiEQvF2= NETTNJJUSU6JRWK=
NCI-H1048 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYLwZ2ROUUN3ME2yNU4zOjV6IN88US=> NYjZPZE2W0GQR1XS
CW-2 NYTBeYdHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEjIW4JKSzVyPUKxMlI4ODVizszN NUXIPZRwW0GQR1XS
HCC2157 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkXpTWM2OD1{MT6zOkDPxE1? NWriVmVbW0GQR1XS
EW-22 NELONm5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2LTSGlEPTB;MkGuN|c3KM7:TR?= NYHWc25kW0GQR1XS
A253 NU\CRmJRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVq2bHlHUUN3ME2yNU41PDhzIN88US=> NUL1[FZKW0GQR1XS
BE-13 MorrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2jmN2lEPTB;MkGuOlEyOyEQvF2= MULTRW5ITVJ?
KINGS-1 Mn\IS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVXJR|UxRTJzLk[zNVYh|ryP NUXFUpB{W0GQR1XS
ETK-1 M{jGOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVPJR|UxRTJzLkixOVIh|ryP NVTQOmlpW0GQR1XS
NCI-H2452 M1jqemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYDoSppMUUN3ME2yNU45PjR5IN88US=> MmfDV2FPT0WU
HPAF-II NWPjeYk6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3jxNWlEPTB;MkGuPFkzOyEQvF2= MoTOV2FPT0WU
D-542MG M{\JVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2TKUWlEPTB;MkGuPVA3QSEQvF2= Mo\hV2FPT0WU
NCI-H630 NYTqZo9mT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUTJR|UxRTJ{LkCyPVYh|ryP M4\WZ3NCVkeHUh?=
TGBC11TKB NFvG[opIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUDJR|UxRTJ{LkC0PUDPxE1? NIjCZXdUSU6JRWK=
BCPAP NEi0VJBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF34ZnRKSzVyPUKyMlYyOSEQvF2= Moi0V2FPT0WU
HLE MmXNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NILM[YNKSzVyPUKyMlY6PyEQvF2= NUHhNWNyW0GQR1XS
NCI-H727 Ml[wS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWnJR|UxRTJ{LkezOUDPxE1? M{Lj[nNCVkeHUh?=
RD MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXjJR|UxRTJ{Lke1NVgh|ryP Ml34V2FPT0WU
NCI-H522 NIT0T5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHnpToRKSzVyPUKyMlg1OzFizszN NUTVfGE2W0GQR1XS
CGTH-W-1 MmLXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGn6enhKSzVyPUKzMlA3PDFizszN NGDIcW9USU6JRWK=
SK-LU-1 MoKxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;QU|BKSzVyPUKzMlQ3QDNizszN MY\TRW5ITVJ?
BB65-RCC MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M37YO2lEPTB;MkOuO|g3OyEQvF2= NXXY[WlVW0GQR1XS
HSC-3 NWS5Wo5MT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4XQ[GlEPTB;MkOuPFUzPyEQvF2= NX;LO4F3W0GQR1XS
SK-MES-1 NHS1SohIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlrHTWM2OD1{ND6wNVYyKM7:TR?= MoDOV2FPT0WU
DB M3Lwe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2n0[WlEPTB;MkSuNVAzQCEQvF2= NFfqfnlUSU6JRWK=
HO-1-N-1 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYXpWZlYUUN3ME2yOE4{ODl|IN88US=> NUDGWJNnW0GQR1XS
MKN1 NWLQWY56T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NITxS|VKSzVyPUK0MlY5KM7:TR?= MYjTRW5ITVJ?
MN-60 Mlu5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4CxUGlEPTB;MkSuPFUyQSEQvF2= NYLIU4pLW0GQR1XS
8505C NF;4ZYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX;JR|UxRTJ3LkG4OFUh|ryP NHyyPJJUSU6JRWK=
COLO-320-HSR MlHDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUK4PWZOUUN3ME2yOU4zOjB6IN88US=> M3LCcnNCVkeHUh?=
BB30-HNC NX\ReIlJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVq4fW1NUUN3ME2yOU4zPDh|IN88US=> M{TpeHNCVkeHUh?=
KM12 NFfIWnhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1PNfWlEPTB;MkWuOVgxPyEQvF2= NXnRNo86W0GQR1XS
NB13 NFXi[YZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmXvTWM2OD1{NT61PFk5KM7:TR?= NHi5SGxUSU6JRWK=
HCC2998 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1nSd2lEPTB;Mk[uNFI5OyEQvF2= NWKxenVmW0GQR1XS
U-118-MG M4X1c2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFnXc2dKSzVyPUK2MlA5ODhizszN MnrUV2FPT0WU
NB10 Mn\5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3LXfGlEPTB;Mk[uNlM1KM7:TR?= NGH2TIFUSU6JRWK=
SK-LMS-1 NYPoNFJtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXPPUGtTUUN3ME2yO{4xPzB2IN88US=> Mni1V2FPT0WU
SW1573 M2fxcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIXOW2lKSzVyPUK3MlEyKM7:TR?= M{LOTHNCVkeHUh?=
LB373-MEL-D NG\VTXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnjITWM2OD1{Nz6xNlk1KM7:TR?= NH;CdlhUSU6JRWK=
DK-MG NFTZb|NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{H1N2lEPTB;MkeuNVgyPyEQvF2= NXzMVpRoW0GQR1XS
RMG-I Mn30S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF;4fmJKSzVyPUK3MlIxOjlizszN MlO0V2FPT0WU
SW1088 MkTnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV;JR|UxRTJ5LkWwOFIh|ryP M4XEbHNCVkeHUh?=
SK-OV-3 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlXRTWM2OD1{Nz63OVk{KM7:TR?= NEHFSpFUSU6JRWK=
KP-N-YN MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVjOd|RjUUN3ME2yO{45ODR|IN88US=> MkTCV2FPT0WU
RPMI-7951 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmSyTWM2OD1{OD6yOFU3KM7:TR?= MnzUV2FPT0WU
CaR-1 MmfxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV\WfY5zUUN3ME2yPE42PTh{IN88US=> MlTQV2FPT0WU
MKN7 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGnBdIFKSzVyPUK4MlU6PjRizszN M2fpVnNCVkeHUh?=
CHP-212 MoLZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3jZd2lEPTB;MkiuO|QxOSEQvF2= M4TYXHNCVkeHUh?=
KYSE-450 NX\CWmpuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUfvb5NwUUN3ME2yPE45ODlzIN88US=> NYPFO5pSW0GQR1XS
RXF393 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXnJR|UxRTJ7LkK5NFYh|ryP NXS0V4tPW0GQR1XS
P30-OHK NIDQeVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXTrc244UUN3ME2yPU4{ODR6IN88US=> M1v4[3NCVkeHUh?=
Ca9-22 NUDOZXlqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnrnTWM2OD1{OT60Nlk6KM7:TR?= NYjMWYNlW0GQR1XS
RT-112 MlnES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHLZNoFKSzVyPUK5MlQ3OTFizszN MXzTRW5ITVJ?
ES1 M3vXcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXrpTpJWUUN3ME2yPU45PTR2IN88US=> NWHpPIdQW0GQR1XS
HCE-4 MnvES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX\JR|UxRTJ7Lki3PFYh|ryP NXu4d3RVW0GQR1XS
AM-38 NFnqVmZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml;qTWM2OD1|MD6wOlA3KM7:TR?= MlLNV2FPT0WU
AsPC-1 NYDGSI5kT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXrJR|UxRTNyLkiwOVMh|ryP MljkV2FPT0WU
TE-9 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlTFTWM2OD1|MD64O|M4KM7:TR?= M3Tae3NCVkeHUh?=
HuP-T4 NX64XlgyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1;0UmlEPTB;M{CuPVY{QCEQvF2= M1vFNXNCVkeHUh?=
LB2518-MEL Ml\VS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV;JR|UxRTNzLkC3OFQh|ryP NI\uXYtUSU6JRWK=
NCI-H1703 NIL6eWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2HxT2lEPTB;M{GuNFkxPSEQvF2= NVvqcVF7W0GQR1XS
NCI-H2228 NHvQR|NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkKzTWM2OD1|MT60OlUyKM7:TR?= MWrTRW5ITVJ?
SCC-4 M4G0OWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEHMN|FKSzVyPUOxMlkyQDFizszN MmD6V2FPT0WU
KNS-81-FD M2nh[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3fobGlEPTB;M{KuNFEzQCEQvF2= NVGxepR4W0GQR1XS
NTERA-S-cl-D1 MkDuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NG\mNoxKSzVyPUOyMlA4OzlizszN M4H1R3NCVkeHUh?=
Daoy NH\hdXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWWwNHQ2UUN3ME2zNk4xQDN6IN88US=> MX3TRW5ITVJ?
ES4 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3XQRWlEPTB;M{KuN|kzOiEQvF2= MVzTRW5ITVJ?
MHH-ES-1 M1vvfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIO5eHFKSzVyPUOyMlQ5PzJizszN NGG4dWFUSU6JRWK=
C-33-A NFj6RVFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2fOWGlEPTB;M{KuO|czQCEQvF2= NXzhO3dMW0GQR1XS
BHY NIPZZWRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1rWNGlEPTB;M{KuPVQ6PSEQvF2= NI[1dpRUSU6JRWK=
Detroit562 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MULJR|UxRTN|Lk[2OVch|ryP Ml;SV2FPT0WU
EW-1 M2PaWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3:4NWlEPTB;M{OuPVMzOiEQvF2= NWTQW5p4W0GQR1XS
NCI-H1395 M2[w[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUPxRWNnUUN3ME2zOE4xPzl7IN88US=> MkDuV2FPT0WU
KM-H2 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MULJR|UxRTN4LkS3OFMh|ryP MlnOV2FPT0WU
NCI-H520 NFjjTXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NITEZlNKSzVyPUO2Mlc2PDFizszN NWDO[YJ[W0GQR1XS
D-392MG NHLmTlJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUTJR|UxRTN5LkOzOFQh|ryP NEPIU5JUSU6JRWK=
NOMO-1 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUfJR|UxRTN5LkiwPFkh|ryP NXewWVhlW0GQR1XS
TE-6 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXzJR|UxRTN6LkGyOEDPxE1? M3vKOXNCVkeHUh?=
HT-3 NH70[nNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVS2WGFPUUN3ME2zPE41PDN4IN88US=> M1jlXnNCVkeHUh?=
RPMI-8226 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHzwbWFKSzVyPUO4Mlk2OTlizszN MkTOV2FPT0WU
U251 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVrz[5Z2UUN3ME2zPU4xOTJ2IN88US=> MmDJV2FPT0WU
GCT MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkXVTWM2OD1|OT6xPFUzKM7:TR?= M2racHNCVkeHUh?=
A431 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEL3eWpKSzVyPUO5MlE5QTRizszN MXXTRW5ITVJ?
TE-12 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3jPNGlEPTB;M{muNlQ1QCEQvF2= MWjTRW5ITVJ?
HMV-II NF7NOVJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIjEWVJKSzVyPUO5MlUxPDdizszN MXfTRW5ITVJ?
IST-MES1 MmOwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVvTflJFUUN3ME20NE4yPTB{IN88US=> NFf0fo9USU6JRWK=
SW13 NEjPdpFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWXJR|UxRTRyLkWxPUDPxE1? M2nRUnNCVkeHUh?=
SF295 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MofxTWM2OD12MD64NFY3KM7:TR?= NGDyV4NUSU6JRWK=
MDA-MB-157 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWrjZlc2UUN3ME20NE46PDZ{IN88US=> NYLIXmQ5W0GQR1XS
TE-1 Mk\kS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkS2TWM2OD12MT64O|E1KM7:TR?= M4\K[XNCVkeHUh?=
HuCCT1 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXLQPYQ6UUN3ME20Nk42Ojh7IN88US=> NEjEdHpUSU6JRWK=
KYSE-510 M3naSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVHGeFdxUUN3ME20N{4yPzV2IN88US=> Mn7aV2FPT0WU
NCI-H358 NVLDcZR5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIHCdXFKSzVyPUS0MlA{ODRizszN NYj2[WtWW0GQR1XS
SW900 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFHWUlhKSzVyPUS0MlA4PThizszN MUXTRW5ITVJ?
CAS-1 MknzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NY\nXohXUUN3ME20OE4xQTlzIN88US=> NGqweItUSU6JRWK=
TE-8 NF7pc5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV7iWWgyUUN3ME20OE42PjV6IN88US=> M1;5T3NCVkeHUh?=
P12-ICHIKAWA M2\F[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXO5VndJUUN3ME20OE43OTF{IN88US=> NWX6Rod2W0GQR1XS
YKG-1 NE\pe5NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGK0R3NKSzVyPUS0Mlc5OSEQvF2= MUfTRW5ITVJ?
SNU-C2B MojtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2DucGlEPTB;NESuO|kxOyEQvF2= NUHLc21GW0GQR1XS
LCLC-103H NGjUSIZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYrnPIxvUUN3ME20OE45PzB|IN88US=> MnfGV2FPT0WU
U-87-MG MojnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTR3LkGwNlIh|ryP Mo\JV2FPT0WU
HAL-01 M{\CNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYO2cplUUUN3ME20OU4yOzd7IN88US=> NFnOdJhUSU6JRWK=
OVCAR-8 MnvBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX21NlNjUUN3ME20OU4{PTZ2IN88US=> NYfX[lhLW0GQR1XS
KYSE-150 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHPmenFKSzVyPUS3MlExPTJizszN M37uPHNCVkeHUh?=
OE33 NVnuSnl{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkjLTWM2OD12Nz6xOFI6KM7:TR?= MYrTRW5ITVJ?
CAL-62 NUe2R5RxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVXZOoI6UUN3ME20O{41ODZ6IN88US=> M3OzVnNCVkeHUh?=
TCCSUP MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWDHTVBjUUN3ME20O{43OjZ2IN88US=> NGPwSI9USU6JRWK=
H4 M3\6W2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1XzTGlEPTB;NEeuOlYzOSEQvF2= M3L5VHNCVkeHUh?=
CP66-MEL NIL3OFJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mo\XTWM2OD12OD6wO|A1KM7:TR?= M{[0d3NCVkeHUh?=
SNB75 MkDWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHjvOYNKSzVyPUS4MlE5PzRizszN M{W2THNCVkeHUh?=
Mo-T NXKwUZRGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYXON29WUUN3ME20PE4zPzlizszN MoPhV2FPT0WU
BT-549 NYD4[JEzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVLkSnhDUUN3ME20PE4{PzJ7IN88US=> M4rTNnNCVkeHUh?=
IGR-1 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVjZbW11UUN3ME20PE43PjR3IN88US=> Mmf3V2FPT0WU
NCI-H1299 MnXlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnXDTWM2OD12OD63NlQ5KM7:TR?= M3:2dXNCVkeHUh?=
ALL-PO MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnTwTWM2OD12OT65NlY5KM7:TR?= MojRV2FPT0WU

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
p-DNA-PKcs / DNA-PKcs / p-ATM / ATM / p-ATR / ATR / Ku70 / p-CHK1 / p-CHK2/ p-AKT / RAD51; 

PubMed: 29344644     


SUNE1 cells were irradiated with 5 Gy in the presence or absence of NU7441 (2 µM). The expression of cell cycle checkpoint proteins and double strand break repair proteins was assayed by western blot analysis at 6 or 12 h post-IR.

p-mTOR(Ser2448) / mTOR / p-S6K(Thr389); 

PubMed: 25714019     


Phosphorylation of mTOR and p70S6K were detected by Western blot analysis 24 hours after treatment.

29344644 25714019
体内研究 NU7441按 10 mg/kg剂量腹腔注射处理携带SW620移植瘤的小鼠,按无毒剂量处理至少4小时,然后提高 Etoposide诱导的肿瘤生长延迟2倍。 [2]

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

细胞实验:

[2]

- 合并
  • Cell lines: SW620, LoVo, V3-YAC和 V3细胞
  • Concentrations: 0.5 μM或 1 μM
  • Incubation Time: 17 小时
  • Method:

    通过克隆实验测定NU7441,Etoposide, Doxorubicin, 和电离辐射作用于SW620, LoVo, V3,和 V3-YAC细胞存活的效果。在有或无 NU7441(0.5 或 1.0 μM)存在时,使用Etoposide 或Doxorubicin处理6孔板或6-cm盘中指数生长的细胞16小时。放射增敏研究中, NU7441加到细胞中,1小时后,使用辐射处理。使用γ-射线 (3.1 Gy/min 137Cesium)处理V3和V3-YAC 细胞。使用可用设备,使用X-射线 (2.9 Gy/min at 230 kV, 10 mA) 处理SW620 和 LoVo 细胞。辐射处理后,在有或无NU7441存在时,细胞再温育16小时。胰蛋白酶消化,收集细胞,计数,然后按每盘 100 到105 的密度接种在10-cm 直径的Petri盘中, 盘中含无药物培养基,用于形成集落。使用结晶紫对集落进行染色,10 到 14天后,使用自动集落计数器计数。


    (Only for Reference)
动物实验:

[2]

- 合并
  • Animal Models: 携带 SW620移植瘤的雌性裸鼠
  • Formulation: 无菌 0.9% NaCl溶液
  • Dosages: 10 mg/kg
  • Administration: 腹腔注射
    (Only for Reference)

溶解度 (25°C)

体外 DMSO 4 mg/mL warmed (9.67 mM)
Water Insoluble
Ethanol Insoluble
体内 从左到右依次将纯溶剂加入产品,现配现用(数据来自Selleck实验检测而非文献):
5% DMSO+30% PEG 300+5% Tween 80+ddH2O
2mg/mL

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 413.49
化学式

C25H19NO3S

CAS号 503468-95-9
储存条件 粉状
溶于溶剂
别名 N/A

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

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操作手册

如果有其他问题,请给我们留言。

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常见问题及建议解决方法

  • 问题 1:

    Could you please suggest formulations of the drug for in vivo injection?

  • 回答:

    We tested the following formulation for in vivo use, 4% DMSO+30% PEG 300+5% Tween 80+ddH2O up to 1mg/mL. It is a clear solution.

  • 问题 2:

    Previous aliquots were clear and colorless while this time, it becomes yellow when the powder was dissolved in DMSO? Could you advice on this?

  • 回答:

    Slight color variation due to different processing is normal and usually doesn't interfere with the function.

DNA-PK Signaling Pathway Map

DNA-PK Inhibitors with Unique Features

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID