NU7441 (KU-57788)

目录号:S2638

NU7441 (KU-57788) Chemical Structure

Molecular Weight(MW): 413.49

NU7441 (KU-57788)是一种高度有效的,选择性DNA-PK抑制剂,在无细胞试验中IC50为14 nM,也会抑制PI3K,IC50为5 μM。它可降低NHEJ的频率,而增强Cas9介导DNA剪接后发生的同源重组修复率。

规格 价格 库存 购买数量  
RMB 565.91 现货
RMB 974.57 现货
RMB 3040.41 现货
RMB 7928.18 现货
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客户使用该产品的6个实验数据:

  • Cells were treated with cisplatin under the following conditions: pretreatment with Nu7026 (Nu7026, 26) or Nu7441 (Nu7441, 41). Before DNA damage, wortmannin was applied at 100 nM for 30 min, Nu7026 at 10 uM for 1 h, Nu7441 at 1 uM for 1 h. Accompanying quantifications of the adjusted nucleolar EU fluorescence are shown. Each condition was normalized to cells treated with DMSO or indicated inhibitors without DNA damaging treatment. Two-way ANOVA was followed by Holm-Sidak's test for the comparison of cells with and without inhibitors. *, **, *** represent P ≤ 0.05, 0.01, 0.001, respectively.

    Nucleic Acids Res 2013 41(15), 7378-86. NU7441 (KU-57788) purchased from Selleck.

    Confocal immunostaining of S2056 phosphorylation of DNA-PKcs following radiation in HEK 293T and p18CycE-expressing cells.

    Nucleic Acids Res 2013 41, 10157-69. NU7441 (KU-57788) purchased from Selleck.

  • (C) Microirradiation live-cell microscopy of U2OS cells stably expressing mEGFP-MacroD2 full-length construct and treated with KU55933 10 μM, VE-821 1 μM, NU7441 1 μM or DMSO. Scale bar, 10 μm.

    Nucleic Acids Res, 2017, 45(1):244-254. NU7441 (KU-57788) purchased from Selleck.

    (C) Immunohistochemically detection of Cleaved Caspase-3 48 h after treatment to measure apoptosis in vivo, induced levels of apoptosis in xenografts treated with radiation in combination with DNA-PKcsi and HT compared to radiation alone. Necrotic areas were observed in xenograft of triple treatment. DNA-PKcsi:NU7441

    Oncotarget, 2016, 7(40): 65504-65513. NU7441 (KU-57788) purchased from Selleck.

  • Validation of activity and specificity of chemical inhibitors of; ATM, ATR, and DNAPK. H460 cells were treated with 1 uM camptothecin (CPT) or 20 ug/ml bleomycin for 1 h in the presence of the indicated inhibitors: DNAPK-i1—NU7026, DNAPK-i2—NU7441. MSH6, fibrillarin, and tubulin were used as loading controls.Effects of DNAPK inhibitors on its autophosphorylation in bleomycin-treated cells.

    Toxicol Sci 2014 10.1093/toxsci/kfu207. NU7441 (KU-57788) purchased from Selleck.

    After starved in serum-free medium for 24h,A549 cells incubated with the indicated concentrations of NU-7441 for 3h,followed by 20-minute stimolation of 100ng/ml EGF.

    Dr. Zhang of Tianjin Medical University. NU7441 (KU-57788) purchased from Selleck.

产品安全说明书

DNA-PK抑制剂选择性比较

生物活性

产品描述 NU7441 (KU-57788)是一种高度有效的,选择性DNA-PK抑制剂,在无细胞试验中IC50为14 nM,也会抑制PI3K,IC50为5 μM。它可降低NHEJ的频率,而增强Cas9介导DNA剪接后发生的同源重组修复率。
靶点
DNA-PK [1]
(Cell-free assay)
14 nM
体外研究

NU7441抑制DNA依赖性蛋白激酶 (DNA-PK) 比抑制其他PI3K相关激酶 (PIKK)家族成员选择性高,IC50 为14 nM。[1] 电离辐射诱导或Etoposide诱导 DNA 损伤后,1 μM NU7441提高γH2AX病灶的持久性。NU7441 浓度为 0.5 μM 或 1 μM时,作用于SW620 和 LoVo细胞,显著提高电离辐射,Etoposide, 和 Doxorubicin 诱导的G2-M累积增多。[2] NU7441浓度为1 μM时,引起 Doxorubicin和电离辐射诱导的DNA双链断裂的持久性,也稍微降低同源重组活性 DNA-PK充足的 M059-Fus-1和 DNA-PK缺陷的 M059 J人类肿瘤细胞。[3] NU7441浓度为 10 μM 时,作用于缺乏和表达polη的细胞,抑制UV诱导 RPA p34过度磷酸化。[4] NU7441 浓度为1 μM时,作用于慢性淋巴细胞性白血病细胞。提高Fludarabine诱导的γH2AX病灶水平,也相应地降低Fludarabine诱导的细胞死亡。[5] NU7441浓度为 1 μM时,作用于慢性淋巴细胞性白血病细胞,抑制Mitoxantrone诱导的DNA-PKcs自磷酸化和修复。[6]它可降低NHEJ的频率,而增强Cas9介导DNA剪接后发生的同源重组修复率 [7]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1770 NFLGTY9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWrCSGFiUUN3ME2wMlAzOTR|IN88US=> NUXsS3NGW0GQR1XS
A172 M3;sV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWjJR|UxRTBwMUWzNVYh|ryP M2D5b3NCVkeHUh?=
NCI-H526 MmDnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIn1OYRKSzVyPUCuNlg1ODdizszN M4XqenNCVkeHUh?=
HDLM-2 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnHuTWM2OD1yLkOyN|Q2KM7:TR?= M4DSfXNCVkeHUh?=
HuO-3N1 M37pO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHPqdVdKSzVyPUCuOFY3OzZizszN NFfjfVVUSU6JRWK=
NCI-SNU-1 MmnjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXPJR|UxRTBwNkC5PVQh|ryP NInzdGdUSU6JRWK=
SK-N-AS Ml2zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWTtU444UUN3ME2wMlYzOjF4IN88US=> NYn0UmhSW0GQR1XS
LoVo NV\LZ|lET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NETreWxKSzVyPUCuPFY4PDlizszN M3\hb3NCVkeHUh?=
LAMA-84 M{[1OWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlTQTWM2OD1yLkm4PFM{KM7:TR?= Ml\IV2FPT0WU
CTB-1 M4\tPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVLJR|UxRTFwMUG1OFYh|ryP NG[2bmtUSU6JRWK=
KP-N-YS MonwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIOxTJFKSzVyPUGuNVQzOzFizszN MmDMV2FPT0WU
HH NIjCU2JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4GwXWlEPTB;MT6xPFA6OyEQvF2= MoHpV2FPT0WU
CHL-1 NWPRUZpoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHzke4NKSzVyPUGuNlE{PjhizszN MVfTRW5ITVJ?
NB7 NHjFS4VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVP3fmV7UUN3ME2xMlI1PzR3IN88US=> NIjE[2RUSU6JRWK=
HL-60 MojOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlrkTWM2OD1zLkO4NVkh|ryP MnzHV2FPT0WU
639-V M4TBeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYjJR|UxRTFwNESxNlgh|ryP MXjTRW5ITVJ?
NCI-H1793 M3fuc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MljITWM2OD1zLkS1PFQh|ryP Mmf3V2FPT0WU
NEC8 MnvaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXTLbnhEUUN3ME2xMlU2OzVizszN NVm3e4lHW0GQR1XS
PA-1 NW\1TZh4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmrmTWM2OD1zLkW4Nlk1KM7:TR?= NFnORo9USU6JRWK=
D-423MG M33TTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlfETWM2OD1zLk[5N|YyKM7:TR?= NF3qZ|FUSU6JRWK=
NCI-H292 NX3vV2o3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX3JR|UxRTFwN{SwNVMh|ryP NIexSIFUSU6JRWK=
SK-MEL-1 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1K2XWlEPTB;MT63PVQ4QSEQvF2= NEnmeJRUSU6JRWK=
LB2241-RCC Ml\sS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml7WTWM2OD1{LkG0NVQ3KM7:TR?= MnvRV2FPT0WU
SK-MEL-3 MlrWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4j1bWlEPTB;Mj6xOlQ6KM7:TR?= NF2yOHdUSU6JRWK=
MHH-PREB-1 NGD6N5dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEnwfnpKSzVyPUKuNVY3ODlizszN NGjQNIhUSU6JRWK=
BFTC-905 MnTmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MljOTWM2OD1{LkG2Olg4KM7:TR?= M3H1R3NCVkeHUh?=
Ramos-2G6-4C10 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NI[zU4tKSzVyPUKuNVk6ODlizszN M4OzWnNCVkeHUh?=
G-361 NVq4PIhqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2DBVmlEPTB;Mj6yNVY5KM7:TR?= M1rmPHNCVkeHUh?=
MOLT-4 NH3qW3FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXmxTHF[UUN3ME2yMlIyQDh6IN88US=> NVfScJJCW0GQR1XS
DEL M3zNRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Moe3TWM2OD1{LkO1OVY1KM7:TR?= NGPxblFUSU6JRWK=
MV-4-11 M3nIV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUPJR|UxRTJwM{ezPUDPxE1? NEHEcWJUSU6JRWK=
SK-NEP-1 NW\HUXhoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFzLWWFKSzVyPUKuN|g4QDNizszN NEn4VHlUSU6JRWK=
RS4-11 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnPMTWM2OD1{LkW2NFI{KM7:TR?= NITyVYhUSU6JRWK=
HuH-7 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXrJR|UxRTJwNU[3NFIh|ryP NEnJeHpUSU6JRWK=
A101D MlP3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGLzW4tKSzVyPUKuOlE{OzhizszN M{fmW3NCVkeHUh?=
KG-1 NWnTZlFsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFnLOJlKSzVyPUKuOlc6OjRizszN MYnTRW5ITVJ?
KALS-1 NUPvbJhST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mle1TWM2OD1{Lk[5OlM{KM7:TR?= NISwS3RUSU6JRWK=
VMRC-RCZ NHLxNZBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVz3N3FQUUN3ME2yMlc4OzJ6IN88US=> NXPSdINNW0GQR1XS
SK-UT-1 NU\MZoFrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1fXVGlEPTB;Mz6xOVMyKM7:TR?= MXrTRW5ITVJ?
SW962 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlLTTWM2OD1|LkKwN|UzKM7:TR?= NH\yWJZUSU6JRWK=
DBTRG-05MG MoDzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTNwMkiwPFUh|ryP NEGwdIxUSU6JRWK=
PANC-08-13 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3vhdWlEPTB;Mz60NVI4QCEQvF2= Ml\tV2FPT0WU
QIMR-WIL M37YN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1KwbWlEPTB;Mz60NVM1OSEQvF2= MU\TRW5ITVJ?
SK-MEL-30 NV6zS3ZNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUPmUWh4UUN3ME2zMlQzPTl6IN88US=> Mk\NV2FPT0WU
697 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX\JR|UxRTNwNES5PVMh|ryP M3rHd3NCVkeHUh?=
NY NHPqNYhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnrxTWM2OD1|LkS1NFIzKM7:TR?= MmS3V2FPT0WU
ES7 M2O5fWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVu2cFB2UUN3ME2zMlQ3PzJ7IN88US=> MnvUV2FPT0WU
JVM-3 MkX1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYnpc5ZtUUN3ME2zMlQ5ODd5IN88US=> NXHXOVI3W0GQR1XS
U031 MnvwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTNwNUmzOlgh|ryP Mm\TV2FPT0WU
BHT-101 NYjZZnFQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWfJR|UxRTNwNUm5PFUh|ryP MUTTRW5ITVJ?
8305C NVTZXGM1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmfjTWM2OD1|Lk[xO|M3KM7:TR?= MmfqV2FPT0WU
MG-63 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnOyTWM2OD1|Lk[yOlc3KM7:TR?= MlLiV2FPT0WU
NOS-1 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmfoTWM2OD1|Lk[1N|EzKM7:TR?= NFvRW2FUSU6JRWK=
YH-13 MkLyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1\ORmlEPTB;Mz64O|E5QSEQvF2= NY\5NWh6W0GQR1XS
LXF-289 NWPzOI8zT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXrJR|UxRTNwOUGwOFEh|ryP NXnkS|R{W0GQR1XS
GOTO NGLBTZlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFq0ZlVKSzVyPUOuPVE1QSEQvF2= MV7TRW5ITVJ?
EKVX MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWfU[llnUUN3ME20MlIzPTJ2IN88US=> M1vJVHNCVkeHUh?=
CAL-51 NF;ZVndIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1zueGlEPTB;ND6yOFg2PCEQvF2= MVrTRW5ITVJ?
AN3-CA NWDDVolVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGnyPJZKSzVyPUSuNlU5OTNizszN MXvTRW5ITVJ?
IA-LM M3nodWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1fCZmlEPTB;ND6yO|k{PSEQvF2= NFLtTFFUSU6JRWK=
KU-19-19 Mm\KS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHLqcJJKSzVyPUSuN|I6OjFizszN NFLPXoxUSU6JRWK=
A704 M2O5XGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV7JR|UxRTRwNEC4PFgh|ryP NVXBTZYxW0GQR1XS
RH-18 Ml\rS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHzDWWRKSzVyPUSuOFQ6PTNizszN M{fpWnNCVkeHUh?=
IST-MEL1 NIXNNGpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGfiRVZKSzVyPUSuOVgzPjNizszN M3fz[nNCVkeHUh?=
LU-134-A MmKwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3jFT2lEPTB;ND61PVY5PSEQvF2= MUHTRW5ITVJ?
SF126 NWC4fosyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVTJR|UxRTRwNkC3NVUh|ryP M4\vVXNCVkeHUh?=
EFO-27 NHuyfVdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWrlRohQUUN3ME20MlY3PTJ3IN88US=> M2\qXnNCVkeHUh?=
SN12C NYK3O25NT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3zB[WlEPTB;ND63NVg6QCEQvF2= MW\TRW5ITVJ?
L-363 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mmf4TWM2OD12Lke3NVE3KM7:TR?= NVzSfI5EW0GQR1XS
MEL-HO MkLGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NID5U2FKSzVyPUSuO|c6QDlizszN M2HUdHNCVkeHUh?=
TYK-nu MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYr1UG1jUUN3ME20MlgxOTJ6IN88US=> MoO4V2FPT0WU
MDA-MB-415 M4D0cGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{fMbWlEPTB;NT6wNFMyPCEQvF2= NXHKUXB{W0GQR1XS
HCC70 NHzRWotIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVzxSYZWUUN3ME21MlA{QTN7IN88US=> MV7TRW5ITVJ?
IGROV-1 NE\VOHhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGHhbFBKSzVyPUWuNlUzQTJizszN NWHPSZhuW0GQR1XS
NCI-H1355 M2DXOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFqxXFVKSzVyPUWuNlk3KM7:TR?= NHjVeFRUSU6JRWK=
23132-87 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnTTTWM2OD13LkOyNFI1KM7:TR?= NIHaclJUSU6JRWK=
NB69 NGD6OJFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVTiWIR6UUN3ME21MlMzPDJizszN MofSV2FPT0WU
HSC-2 NH;KblRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIjGeFZKSzVyPUWuOFE4PzNizszN NIDzOXdUSU6JRWK=
KYSE-410 NVTwZWZyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX\JR|UxRTVwNEe2N|Yh|ryP NUOyRnB{W0GQR1XS
GCIY MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2jNT2lEPTB;NT61NVM4QCEQvF2= M4O4bXNCVkeHUh?=
A427 NHHLfWhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoDhTWM2OD13LkWzOlYyKM7:TR?= M1fLdHNCVkeHUh?=
ChaGo-K-1 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MY\JR|UxRTVwNU[1PVkh|ryP Mmq4V2FPT0WU
PFSK-1 M4j1bGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWP5VVBJUUN3ME21MlYzOTl2IN88US=> NUPGUpJ1W0GQR1XS
MLMA NIq3OHpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUTJR|UxRTVwOEO2NFYh|ryP MlfjV2FPT0WU
RVH-421 NHewT|JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWXORmN4UUN3ME22MlA4OzN6IN88US=> MV7TRW5ITVJ?
LB1047-RCC NVu3OYRbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYDJR|UxRTZwMUe1NlIh|ryP M3H5d3NCVkeHUh?=
MHH-NB-11 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1fJT2lEPTB;Nj6zNlczOSEQvF2= NF\SSZRUSU6JRWK=
J-RT3-T3-5 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYHJR|UxRTZwNkOyPVEh|ryP MUDTRW5ITVJ?
UM-UC-3 MnzRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYnJR|UxRTZwNkSzN|Qh|ryP Mn7IV2FPT0WU
IST-SL1 NUezT41IT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFr6bZRKSzVyPU[uOlk{PjlizszN M2G2V3NCVkeHUh?=
NB14 MmPjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFrQV4RKSzVyPU[uO|k4PjFizszN NIHOdIFUSU6JRWK=
NBsusSR M1zKcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGXidYVKSzVyPU[uPFI2ODJizszN NWrMXmRQW0GQR1XS
D-263MG NHTvbmRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFHtcVVKSzVyPU[uPVExPjhizszN MXnTRW5ITVJ?
NCI-H2347 M37CNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHjrdpRKSzVyPU[uPVMzOTNizszN MormV2FPT0WU
ES8 M1vISmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEnXblhKSzVyPU[uPVc2QDhizszN M17qcnNCVkeHUh?=
786-0 M1:4OGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn60TWM2OD15LkC5O|g3KM7:TR?= NIjCTnJUSU6JRWK=
EPLC-272H NV\n[lliT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkLHTWM2OD15LkG2NlQ3KM7:TR?= MmPwV2FPT0WU
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NCI-H82 NIjjeGtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2PBVGlEPTB;Nz6yOlY2QSEQvF2= NXPVbHh6W0GQR1XS
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SW982 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYfJR|UxRTdwM{CyNFMh|ryP MmXQV2FPT0WU
OVCAR-4 NYfXUoxZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXPyZ|FxUUN3ME23MlMyOzJ6IN88US=> NEniNHJUSU6JRWK=
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AU565 MlvLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUTLdGJuUUN3ME23MlU6QDN|IN88US=> NEfjSXJUSU6JRWK=
GAMG MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkfLTWM2OD15Lk[0NVMyKM7:TR?= M13NeHNCVkeHUh?=
HuO9 NFTMVWtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUHJR|UxRTdwN{G3OFMh|ryP MVHTRW5ITVJ?
ACN MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHq1O|dKSzVyPUeuO|Q{OyEQvF2= M3SxUXNCVkeHUh?=
RO82-W-1 NV;kb4k3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVXs[JV2UUN3ME23Mlc1PTN|IN88US=> MUDTRW5ITVJ?
NKM-1 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVnJR|UxRTdwN{S5OVUh|ryP NG\QflVUSU6JRWK=
CAL-12T MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2jmPWlEPTB;Nz65OFM2OiEQvF2= MYPTRW5ITVJ?
FADU M2rXW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUjJR|UxRThwMEO2OVQh|ryP MnHtV2FPT0WU
NCI-H28 NFzDU4pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkDkTWM2OD16LkG2PVYzKM7:TR?= NWPZRXQyW0GQR1XS
LCLC-97TM1 M4jwdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M33hemlEPTB;OD6yNVEzOiEQvF2= NUjSSpFPW0GQR1XS
CHP-134 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVXJR|UxRThwMkSxPFUh|ryP NHrIS2tUSU6JRWK=
HT-1080 MnOzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoTrTWM2OD16LkK1NFk{KM7:TR?= NXz3fogyW0GQR1XS
PC-3 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF7DSJlKSzVyPUiuNlc{QTJizszN Mn;CV2FPT0WU
SNU-449 MlroS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4TvV2lEPTB;OD6yO|k{KM7:TR?= NGX4[plUSU6JRWK=
VA-ES-BJ NXPiWWc6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlfWTWM2OD16LkO0Olg3KM7:TR?= Mn2yV2FPT0WU
HT NFLYe5ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVjXNZo6UUN3ME24MlM3PDlizszN MW\TRW5ITVJ?
HOS MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{n4XGlEPTB;OD6zO|U5QSEQvF2= M3jpUHNCVkeHUh?=
KNS-62 MlLiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWnWU3ZZUUN3ME24MlM4PzZ{IN88US=> MUTTRW5ITVJ?
OAW-42 M3fGRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYjJR|UxRThwOUW5OlQh|ryP MojvV2FPT0WU
A549 M2Toemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M37PcGlEPTB;OT6wPVYyOiEQvF2= NUTvdJF1W0GQR1XS
CAKI-1 NXG0RmFCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnPhTWM2OD17LkG2OlEh|ryP NE\1TmJUSU6JRWK=
HCC1937 NVjDcmg2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnTHTWM2OD17Lk[5PFY2KM7:TR?= NYPNW4pCW0GQR1XS
GI-ME-N NV7iT2lbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVj3eow3UUN3ME25MlcxOTN5IN88US=> MmPEV2FPT0WU
DU-4475 MknXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHfPUmtKSzVyPUmuPVY6OzlizszN MUXTRW5ITVJ?
EM-2 NYOydmU1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH3rbodKSzVyPUGwMlI1OjZizszN MYPTRW5ITVJ?
NCI-H1755 NFTpNpNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2jzSWlEPTB;MUCuNlQzQCEQvF2= MV7TRW5ITVJ?
NCI-H1437 MmHOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEL4NHpKSzVyPUGwMlU4OjVizszN NXvNc4R2W0GQR1XS
VM-CUB-1 NGTDcGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFyyNYRKSzVyPUGwMlYyPjRizszN MUfTRW5ITVJ?
A2058 Mo\xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2PCUGlEPTB;MUCuOlQxPCEQvF2= Ml\CV2FPT0WU
BPH-1 MmPUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGf2b3FKSzVyPUGwMlcyPDVizszN M{LLPXNCVkeHUh?=
NB5 NXi1flZYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3LtN2lEPTB;MUCuO|U2QSEQvF2= MX\TRW5ITVJ?
G-401 M2O2Rmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXXJR|UxRTFyLke2NlYh|ryP MXrTRW5ITVJ?
CAL-72 M3S3cmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MorxTWM2OD1zMD64NFk1KM7:TR?= MlXQV2FPT0WU
SK-MEL-28 NX7PcINLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M33lU2lEPTB;MUCuPFIxOiEQvF2= MWHTRW5ITVJ?
C32 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2[0emlEPTB;MUCuPFM1PyEQvF2= NFLCO2lUSU6JRWK=
NCI-H1155 NFThU|FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{i5cGlEPTB;MUCuPFM4PiEQvF2= MmnaV2FPT0WU
BB49-HNC M1vWOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXjJR|UxRTFyLki1PFYh|ryP NHO5XIRUSU6JRWK=
GMS-10 NYfCVoJTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmfLTWM2OD1zMD64PVcyKM7:TR?= NGTkeoJUSU6JRWK=
K5 NVOxVGlMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVLJR|UxRTFyLkmwO|Eh|ryP MlHaV2FPT0WU
OS-RC-2 NUjz[3Q4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2fMdmlEPTB;MUGuNFU2QSEQvF2= MV;TRW5ITVJ?
HTC-C3 NEHodoRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmTLTWM2OD1zMT6wO|E1KM7:TR?= NX\0WYt1W0GQR1XS
LB996-RCC NUSyd3ZTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NITp[45KSzVyPUGxMlA4OjNizszN NYnQXFg3W0GQR1XS
NCI-H1563 M{ThNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MknNTWM2OD1zMT6xNFEyKM7:TR?= MlflV2FPT0WU
CAL-54 NYrtSoZMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{PwXmlEPTB;MUGuOFgyOSEQvF2= MUjTRW5ITVJ?
WM-115 M2rLbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFHYeHJKSzVyPUGxMlY5OjRizszN NHzublBUSU6JRWK=
COLO-684 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYjJR|UxRTFzLkeyOlch|ryP MXLTRW5ITVJ?
HOP-62 MlTlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUj6eI1pUUN3ME2xNU44PTB6IN88US=> NVjYb5lnW0GQR1XS
NCI-H650 NGnMd21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4HIe2lEPTB;MUGuPFk3OSEQvF2= MVLTRW5ITVJ?
TE-11 M3HGd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFm5SWRKSzVyPUGxMlk{OTVizszN MmjRV2FPT0WU
COLO-679 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3r5TWlEPTB;MUGuPVQ3KM7:TR?= NWPZVHBvW0GQR1XS
FTC-133 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnPHTWM2OD1zMj6wNFc3KM7:TR?= MmDFV2FPT0WU
D-283MED NU\3VI9wT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX7XbpVWUUN3ME2xNk4xPTZ7IN88US=> M4W3NnNCVkeHUh?=
SK-PN-DW M1vrbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX;LW49nUUN3ME2xNk4yQTB{IN88US=> NYLZS2FZW0GQR1XS
BALL-1 NHz1doRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVHXeYtoUUN3ME2xNk4zPjZ{IN88US=> MVXTRW5ITVJ?
GT3TKB NHXSXndIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4jaOmlEPTB;MUKuN|A4PCEQvF2= Mk\CV2FPT0WU
HOP-92 MlHNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWT5cIJEUUN3ME2xNk42OjN|IN88US=> MVnTRW5ITVJ?
M14 Mke4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWXYN4l1UUN3ME2xN{4xOzN3IN88US=> MoTWV2FPT0WU
SKG-IIIa M3zqNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYrJR|UxRTF|LkC1OVQh|ryP MXPTRW5ITVJ?
Becker MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnnPTWM2OD1zMz6wOVgh|ryP MmHNV2FPT0WU
ES5 M1HtOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWXJR|UxRTF|LkGzOVYh|ryP Mmm0V2FPT0WU
NCI-H2030 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1HncmlEPTB;MUOuNlA3OiEQvF2= NHS3PZNUSU6JRWK=
SNU-423 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFnxR|hKSzVyPUGzMlM5OSEQvF2= M37mUXNCVkeHUh?=
CP50-MEL-B NEfaRoZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWfJR|UxRTF|Lk[yN|Ih|ryP M1fFbnNCVkeHUh?=
NCI-H1092 M{HyOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGT2fJNKSzVyPUGzMlc1PzVizszN NGPYVFhUSU6JRWK=
8-MG-BA NF3ZfmZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYPLWowzUUN3ME2xN{44PTF|IN88US=> NGCyR5dUSU6JRWK=
CAL-27 M3HPcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2O0bmlEPTB;MUSuNFczPyEQvF2= M2S4bXNCVkeHUh?=
AGS NHe5OIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH;6NFZKSzVyPUG0MlE{OTlizszN M3[3TnNCVkeHUh?=
MZ2-MEL NVz5bmxST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3HXOGlEPTB;MUSuNVQ5QCEQvF2= M{LxRnNCVkeHUh?=
BFTC-909 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYXTWFFtUUN3ME2xOE42ODV3IN88US=> MX;TRW5ITVJ?
D-566MG MnyxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXzJR|UxRTF2Lke3NFYh|ryP MmrTV2FPT0WU
MZ7-mel MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnjGTWM2OD1zNT6xNFY4KM7:TR?= MWPTRW5ITVJ?
TE-5 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml[1TWM2OD1zNT6yN|M{KM7:TR?= MYHTRW5ITVJ?
647-V MmrhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MY\JR|UxRTF3LkK3NFUh|ryP M3TQdXNCVkeHUh?=
DMS-114 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2j0SGlEPTB;MUWuN|I6OSEQvF2= NGexPJJUSU6JRWK=
ME-180 NGiycmxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFL3do9KSzVyPUG1MlQ4QDNizszN M33LUXNCVkeHUh?=
MS-1 NILtNVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHr4[GtKSzVyPUG1MlU3OjNizszN MVLTRW5ITVJ?
NUGC-3 NVPDd|NxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mlq1TWM2OD1zNT62NlQ2KM7:TR?= NITE[o1USU6JRWK=
GB-1 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYfkPGhXUUN3ME2xOU43PDN5IN88US=> NFnKc2JUSU6JRWK=
LOXIMVI MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUjJR|UxRTF3Lki5NVkh|ryP MmTSV2FPT0WU
NCI-H1304 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXvWXnhpUUN3ME2xOU45QTJ6IN88US=> NUHheohJW0GQR1XS
KURAMOCHI M3PUemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUOwNJZFUUN3ME2xOU46PzFizszN M1PDfnNCVkeHUh?=
SW1783 MonFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn3OTWM2OD1zNj6wPVk{KM7:TR?= M1i1OHNCVkeHUh?=
EGI-1 MmTXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1yzZWlEPTB;MU[uOVM3PSEQvF2= NVvSc48xW0GQR1XS
KGN MojzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoLITWM2OD1zNj61OVg3KM7:TR?= M1;Oc3NCVkeHUh?=
PANC-03-27 NIfuT2dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mlq2TWM2OD1zNj63OlYzKM7:TR?= MnriV2FPT0WU
RH-1 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NW\WNpNvUUN3ME2xOk45OjVizszN NIrRUWlUSU6JRWK=
HT-1376 NI\JVlBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV;JR|UxRTF4Lki0OFYh|ryP NYHmOYwyW0GQR1XS
ZR-75-30 M2LL[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHLiSGtKSzVyPUG2Mlk{PjFizszN NUnVb29HW0GQR1XS
TI-73 MkXHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkmzTWM2OD1zNj65OFA5KM7:TR?= MYXTRW5ITVJ?
TK10 NHLkVJJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2DhXmlEPTB;MUeuNFA4QSEQvF2= NV[3dJRTW0GQR1XS
SW684 NV:wSI9OT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{PR[GlEPTB;MUeuNFE2PCEQvF2= Ml73V2FPT0WU
RPMI-8866 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkHTTWM2OD1zNz6wOlk6KM7:TR?= M3PoZXNCVkeHUh?=
LNCaP-Clone-FGC M2fS[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn20TWM2OD1zNz61NlAyKM7:TR?= NV;qUoRoW0GQR1XS
NCI-H2291 NVu2XJFUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFjIOnJKSzVyPUG4MlQ{PDVizszN NInmfVBUSU6JRWK=
T47D NFX6ZoxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1;IS2lEPTB;MUiuOFg5KM7:TR?= MVHTRW5ITVJ?
A204 M2jkSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1XL[WlEPTB;MUiuOVQ2OiEQvF2= M1XoO3NCVkeHUh?=
HT-144 M3nzd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3zSbmlEPTB;MUiuO|QzPyEQvF2= M4PEbnNCVkeHUh?=
MDA-MB-361 NEPWSGlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVjJR|UxRTF7LkC3NVQh|ryP MmrmV2FPT0WU
HCC1806 NGTBNZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWLUfVJVUUN3ME2xPU4yPTlzIN88US=> MmnuV2FPT0WU
NCI-H596 MlH6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYHJR|UxRTF7Lk[zPVEh|ryP NHnRZ|NUSU6JRWK=
K-562 NUj5OG5MT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVLVN5ZoUUN3ME2xPU45QTJ4IN88US=> NVXHTWZYW0GQR1XS
D-336MG NVrKNpRTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3jv[mlEPTB;MUmuPVMzOiEQvF2= MV\TRW5ITVJ?
SK-MEL-2 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVTJR|UxRTJyLkG1OVkh|ryP MWXTRW5ITVJ?
HEC-1 NGruSoFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoruTWM2OD1{MD60PVc5KM7:TR?= MVfTRW5ITVJ?
EW-13 NGjFXllIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFnr[oNKSzVyPUKwMlU1PDNizszN MXjTRW5ITVJ?
Hs-578-T NXTaW4RWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFLWTJBKSzVyPUKwMlU2QDNizszN NH25Z|ZUSU6JRWK=
SJSA-1 MoXrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVvkN4RpUUN3ME2yNE42Pjh6IN88US=> M3;5d3NCVkeHUh?=
RCC10RGB M2Th[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXnJR|UxRTJyLk[3NVkh|ryP NVPybGZYW0GQR1XS
LAN-6 NGWwbnNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{iwUGlEPTB;MkGuNFM6PiEQvF2= NHnLOXVUSU6JRWK=
NCI-H1048 NUjn[HlVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4\JPWlEPTB;MkGuNlI2QCEQvF2= NYC5WZEyW0GQR1XS
CW-2 M1faSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVi2N4JRUUN3ME2yNU4zPzB3IN88US=> NYK2V5RpW0GQR1XS
HCC2157 MnjoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{TjdWlEPTB;MkGuN|Yh|ryP MUnTRW5ITVJ?
EW-22 MkH0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NITz[3pKSzVyPUKxMlM4PiEQvF2= M3HwNXNCVkeHUh?=
A253 NX:xR5oxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWL5emViUUN3ME2yNU41PDhzIN88US=> M133fHNCVkeHUh?=
BE-13 NWDXbJJlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoeyTWM2OD1{MT62NVE{KM7:TR?= M1mxVXNCVkeHUh?=
KINGS-1 Mm\1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVjJR|UxRTJzLk[zNVYh|ryP NEXEdoFUSU6JRWK=
ETK-1 M{LaW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkjmTWM2OD1{MT64NVUzKM7:TR?= M2ntXXNCVkeHUh?=
NCI-H2452 NYrONHpST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlLMTWM2OD1{MT64OlQ4KM7:TR?= M4ezSnNCVkeHUh?=
HPAF-II NVT2RmMyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFTtb49KSzVyPUKxMlg6OjNizszN MV\TRW5ITVJ?
D-542MG M{TUfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1S1ZmlEPTB;MkGuPVA3QSEQvF2= MmnMV2FPT0WU
NCI-H630 Ml\jS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXLJR|UxRTJ{LkCyPVYh|ryP MUXTRW5ITVJ?
TGBC11TKB MorsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2\6b2lEPTB;MkKuNFQ6KM7:TR?= NIHkTWRUSU6JRWK=
BCPAP NIr0RZhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYXHW49iUUN3ME2yNk43OTFizszN NX[2e3FHW0GQR1XS
HLE NE[we|BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGPle2VKSzVyPUKyMlY6PyEQvF2= MVzTRW5ITVJ?
NCI-H727 NFPIVGhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXPE[nRsUUN3ME2yNk44OzVizszN MVLTRW5ITVJ?
RD M4jBb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mm\xTWM2OD1{Mj63OVE5KM7:TR?= NE\zWXlUSU6JRWK=
NCI-H522 M4LxTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIDabYNKSzVyPUKyMlg1OzFizszN MnzUV2FPT0WU
CGTH-W-1 NXizNHMxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX7SPYx7UUN3ME2yN{4xPjRzIN88US=> M2jLT3NCVkeHUh?=
SK-LU-1 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX3JR|UxRTJ|LkS2PFMh|ryP MV;TRW5ITVJ?
BB65-RCC NW\OS|BwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoixTWM2OD1{Mz63PFY{KM7:TR?= MVTTRW5ITVJ?
HSC-3 NGTDTnpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFTJd29KSzVyPUKzMlg2OjdizszN MYTTRW5ITVJ?
SK-MES-1 NWmybVhsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV;JR|UxRTJ2LkCxOlEh|ryP Ml\iV2FPT0WU
DB MkjQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NInxSWFKSzVyPUK0MlExOjhizszN MXrTRW5ITVJ?
HO-1-N-1 NFnvN5dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3P5U2lEPTB;MkSuN|A6OyEQvF2= M2DxO3NCVkeHUh?=
MKN1 NVrPepJ{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWT1W|FVUUN3ME2yOE43QCEQvF2= MX3TRW5ITVJ?
MN-60 MlrTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHPUZWVKSzVyPUK0Mlg2OTlizszN MUjTRW5ITVJ?
8505C MmDwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1rhTmlEPTB;MkWuNVg1PSEQvF2= M4j3bXNCVkeHUh?=
COLO-320-HSR MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXfJR|UxRTJ3LkKyNFgh|ryP M4WyXXNCVkeHUh?=
BB30-HNC MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHX2RpNKSzVyPUK1MlI1QDNizszN MmT2V2FPT0WU
KM12 MmTNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX\JR|UxRTJ3LkW4NFch|ryP NVTnOW1oW0GQR1XS
NB13 MoLlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF7nTHpKSzVyPUK1MlU5QThizszN NH\LSoxUSU6JRWK=
HCC2998 Mln0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYnJR|UxRTJ4LkCyPFMh|ryP MoXhV2FPT0WU
U-118-MG M4PjN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmCwTWM2OD1{Nj6wPFA5KM7:TR?= NXvDO3NwW0GQR1XS
NB10 MoPCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn;wTWM2OD1{Nj6yN|Qh|ryP M2fKXXNCVkeHUh?=
SK-LMS-1 M{\mNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4LIOWlEPTB;MkeuNFcxPCEQvF2= NWizRWppW0GQR1XS
SW1573 NFfST2NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmLDTWM2OD1{Nz6xNUDPxE1? NX\aNnoyW0GQR1XS
LB373-MEL-D M3fubGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnPMTWM2OD1{Nz6xNlk1KM7:TR?= MV\TRW5ITVJ?
DK-MG MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3fMT2lEPTB;MkeuNVgyPyEQvF2= NULoXFQ{W0GQR1XS
RMG-I NXe5VYVCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn[3TWM2OD1{Nz6yNFI6KM7:TR?= NIC0U|hUSU6JRWK=
SW1088 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmPxTWM2OD1{Nz61NFQzKM7:TR?= MXjTRW5ITVJ?
SK-OV-3 M1nMbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mnr3TWM2OD1{Nz63OVk{KM7:TR?= NWe4U415W0GQR1XS
KP-N-YN M{f2W2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFfQUXNKSzVyPUK3MlgxPDNizszN Ml;0V2FPT0WU
RPMI-7951 NUPOfXF3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn3tTWM2OD1{OD6yOFU3KM7:TR?= NIDzboJUSU6JRWK=
CaR-1 MkPSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHjOUGZKSzVyPUK4MlU2QDJizszN Ml\xV2FPT0WU
MKN7 Mnn2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGTvc4FKSzVyPUK4MlU6PjRizszN Mk\1V2FPT0WU
CHP-212 NHHUR4tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVzmPYhWUUN3ME2yPE44PDBzIN88US=> M2HUZnNCVkeHUh?=
KYSE-450 MnfwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHHNfm9KSzVyPUK4MlgxQTFizszN MmjhV2FPT0WU
RXF393 M{\yVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUnJR|UxRTJ7LkK5NFYh|ryP NHLFfHBUSU6JRWK=
P30-OHK MmXRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3rFb2lEPTB;MkmuN|A1QCEQvF2= M1TPZ3NCVkeHUh?=
Ca9-22 M3jv[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYGzeoRxUUN3ME2yPU41Ojl7IN88US=> M3rsN3NCVkeHUh?=
RT-112 M3;Fe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmrxTWM2OD1{OT60OlEyKM7:TR?= NWDEZXJtW0GQR1XS
ES1 NXTyZ2JMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYXUUZMxUUN3ME2yPU45PTR2IN88US=> MmjRV2FPT0WU
HCE-4 NHPqUYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1H3XmlEPTB;MkmuPFc5PiEQvF2= MlrmV2FPT0WU
AM-38 MmjMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXrJR|UxRTNyLkC2NFYh|ryP NWfSNW12W0GQR1XS
AsPC-1 M{nKPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWrJR|UxRTNyLkiwOVMh|ryP Ml;JV2FPT0WU
TE-9 M4DoNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWXSdppiUUN3ME2zNE45PzN5IN88US=> MXvTRW5ITVJ?
HuP-T4 NYTiWXhxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFewR2dKSzVyPUOwMlk3OzhizszN M3;hSnNCVkeHUh?=
LB2518-MEL MlHZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH\BOVBKSzVyPUOxMlA4PDRizszN MVfTRW5ITVJ?
NCI-H1703 M4PwT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkHuTWM2OD1|MT6wPVA2KM7:TR?= Ml3DV2FPT0WU
NCI-H2228 NEe0XFBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIfNVXhKSzVyPUOxMlQ3PTFizszN MWfTRW5ITVJ?
SCC-4 NGf5dW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX;seZRvUUN3ME2zNU46OThzIN88US=> M1fRZnNCVkeHUh?=
KNS-81-FD NWO4UGd4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYfJR|UxRTN{LkCxNlgh|ryP M{HSZ3NCVkeHUh?=
NTERA-S-cl-D1 NGW0PWxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFL6ZpFKSzVyPUOyMlA4OzlizszN NVjFcIxEW0GQR1XS
Daoy MoLoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXWzWGFHUUN3ME2zNk4xQDN6IN88US=> NU\MT2RsW0GQR1XS
ES4 MlHnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWrJR|UxRTN{LkO5NlIh|ryP NWj6TZZWW0GQR1XS
MHH-ES-1 NWricXpGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFS2bmhKSzVyPUOyMlQ5PzJizszN NXLvR4o6W0GQR1XS
C-33-A M{KwT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUjJR|UxRTN{Lke3Nlgh|ryP NYDmSnF[W0GQR1XS
BHY Mk\LS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGnmTm1KSzVyPUOyMlk1QTVizszN M1G2PHNCVkeHUh?=
Detroit562 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1fCO2lEPTB;M{OuOlY2PyEQvF2= NGm0bFdUSU6JRWK=
EW-1 MlH2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUPJR|UxRTN|LkmzNlIh|ryP NF3mb4JUSU6JRWK=
NCI-H1395 M4\X[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NI[2fY5KSzVyPUO0MlA4QTlizszN MoPSV2FPT0WU
KM-H2 MkKzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoHNTWM2OD1|Nj60O|Q{KM7:TR?= MWnTRW5ITVJ?
NCI-H520 NI\2NmdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mk\MTWM2OD1|Nj63OVQyKM7:TR?= MXjTRW5ITVJ?
D-392MG MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWTJR|UxRTN5LkOzOFQh|ryP Ml;2V2FPT0WU
NOMO-1 NWKwepdlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUDMfIY{UUN3ME2zO{45ODh7IN88US=> MVvTRW5ITVJ?
TE-6 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX3JR|UxRTN6LkGyOEDPxE1? Mn;OV2FPT0WU
HT-3 NV;zR|RiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHHYdldKSzVyPUO4MlQ1OzZizszN Mlm3V2FPT0WU
RPMI-8226 MoPJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGHYd5FKSzVyPUO4Mlk2OTlizszN MVLTRW5ITVJ?
U251 M4PvVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M17yWmlEPTB;M{muNFEzPCEQvF2= MoHHV2FPT0WU
GCT MoCxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXrqcXlSUUN3ME2zPU4yQDV{IN88US=> NULzVo5NW0GQR1XS
A431 NFvyWI1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTN7LkG4PVQh|ryP NWnZXFRTW0GQR1XS
TE-12 M1LSemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV7PPXpDUUN3ME2zPU4zPDR6IN88US=> NWT0XIF6W0GQR1XS
HMV-II NGq3WItIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnPSTWM2OD1|OT61NFQ4KM7:TR?= MoTYV2FPT0WU
IST-MES1 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWDJR|UxRTRyLkG1NFIh|ryP NFTjcHdUSU6JRWK=
SW13 NGD3d4lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MljyTWM2OD12MD61NVkh|ryP MkDUV2FPT0WU
SF295 NXXKdHFsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlThTWM2OD12MD64NFY3KM7:TR?= NYnEVIFKW0GQR1XS
MDA-MB-157 MnzUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEfzVHpKSzVyPUSwMlk1PjJizszN M2OwfHNCVkeHUh?=
TE-1 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1vwZ2lEPTB;NEGuPFcyPCEQvF2= MWXTRW5ITVJ?
HuCCT1 M2jhWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFfZPYtKSzVyPUSyMlUzQDlizszN NUTJSpBMW0GQR1XS
KYSE-510 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF\1bJNKSzVyPUSzMlE4PTRizszN NEe1RoRUSU6JRWK=
NCI-H358 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3PxSWlEPTB;NESuNFMxPCEQvF2= M2fwdHNCVkeHUh?=
SW900 MnvIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlWxTWM2OD12ND6wO|U5KM7:TR?= NFvwbpZUSU6JRWK=
CAS-1 NXGwfHRwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUfWT5BjUUN3ME20OE4xQTlzIN88US=> NETQRnVUSU6JRWK=
TE-8 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEnWdmNKSzVyPUS0MlU3PThizszN MXLTRW5ITVJ?
P12-ICHIKAWA NXztcXluT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3PrUWlEPTB;NESuOlEyOiEQvF2= NGX1NZlUSU6JRWK=
YKG-1 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYnJR|UxRTR2Lke4NUDPxE1? NUP6R2RIW0GQR1XS
SNU-C2B MlHES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHTUZWFKSzVyPUS0Mlc6ODNizszN MWrTRW5ITVJ?
LCLC-103H MnXSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1XCNGlEPTB;NESuPFcxOyEQvF2= MkDTV2FPT0WU
U-87-MG NW\3bnRrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVTEeoNKUUN3ME20OU4yODJ{IN88US=> NHjZSXNUSU6JRWK=
HAL-01 MnHIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4fTemlEPTB;NEWuNVM4QSEQvF2= M4jYeXNCVkeHUh?=
OVCAR-8 NVHCS442T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3izWWlEPTB;NEWuN|U3PCEQvF2= MV3TRW5ITVJ?
KYSE-150 M4raeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlL2TWM2OD12Nz6xNFUzKM7:TR?= M{[yOXNCVkeHUh?=
OE33 M3;3Xmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4jnW2lEPTB;NEeuNVQzQSEQvF2= M1TnSXNCVkeHUh?=
CAL-62 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGPYTlBKSzVyPUS3MlQxPjhizszN MonZV2FPT0WU
TCCSUP MkLxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVfJR|UxRTR5Lk[yOlQh|ryP M3rsW3NCVkeHUh?=
H4 MlfJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2TvdGlEPTB;NEeuOlYzOSEQvF2= M4HVfnNCVkeHUh?=
CP66-MEL NES1SlNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH7tcWRKSzVyPUS4MlA4ODRizszN M3;YRnNCVkeHUh?=
SNB75 MkPzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXPGUI5IUUN3ME20PE4yQDd2IN88US=> NEDPOVBUSU6JRWK=
Mo-T NXPJVYd[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlHwTWM2OD12OD6yO|kh|ryP Ml;HV2FPT0WU
BT-549 MnnNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXXaN|NHUUN3ME20PE4{PzJ7IN88US=> M3;McHNCVkeHUh?=
IGR-1 M1v2c2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlLlTWM2OD12OD62OlQ2KM7:TR?= MVnTRW5ITVJ?
NCI-H1299 NILuPXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWrPN4p6UUN3ME20PE44OjR6IN88US=> M4G3S3NCVkeHUh?=
ALL-PO NGP5fphIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MorQTWM2OD12OT65NlY5KM7:TR?= NF3TS2VUSU6JRWK=

... Click to View More Cell Line Experimental Data

体内研究 NU7441按 10 mg/kg剂量腹腔注射处理携带SW620移植瘤的小鼠,按无毒剂量处理至少4小时,然后提高 Etoposide诱导的肿瘤生长延迟2倍。 [2]

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

细胞实验:

[2]

+ 展开
  • Cell lines: SW620, LoVo, V3-YAC和 V3细胞
  • Concentrations: 0.5 μM或 1 μM
  • Incubation Time: 17 小时
  • Method:

    通过克隆实验测定NU7441,Etoposide, Doxorubicin, 和电离辐射作用于SW620, LoVo, V3,和 V3-YAC细胞存活的效果。在有或无 NU7441(0.5 或 1.0 μM)存在时,使用Etoposide 或Doxorubicin处理6孔板或6-cm盘中指数生长的细胞16小时。放射增敏研究中, NU7441加到细胞中,1小时后,使用辐射处理。使用γ-射线 (3.1 Gy/min 137Cesium)处理V3和V3-YAC 细胞。使用可用设备,使用X-射线 (2.9 Gy/min at 230 kV, 10 mA) 处理SW620 和 LoVo 细胞。辐射处理后,在有或无NU7441存在时,细胞再温育16小时。胰蛋白酶消化,收集细胞,计数,然后按每盘 100 到105 的密度接种在10-cm 直径的Petri盘中, 盘中含无药物培养基,用于形成集落。使用结晶紫对集落进行染色,10 到 14天后,使用自动集落计数器计数。


    (Only for Reference)
动物实验:

[2]

+ 展开
  • Animal Models: 携带 SW620移植瘤的雌性裸鼠
  • Formulation: 无菌 0.9% NaCl溶液
  • Dosages: 10 mg/kg
  • Administration: 腹腔注射
    (Only for Reference)

溶解度 (25°C)

体外 DMSO 4 mg/mL warmed (9.67 mM)
Water Insoluble
Ethanol Insoluble
体内 从左到右依次将纯溶剂加入产品,现配现用(数据来自Selleck实验检测而非文献):
5% DMSO+30% PEG 300+5% Tween 80+ddH2O
2mg/mL

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 413.49
化学式

C25H19NO3S

CAS号 503468-95-9
稳定性 powder
in solvent
别名 N/A

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

技术支持

在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-668-6834,或者技术支持邮箱tech@selleck.cn,直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题,请给我们留言。

  • * 必填项

常见问题及建议解决方法

  • 问题 1:

    Could you please suggest formulations of the drug for in vivo injection?

  • 回答:

    We tested the following formulation for in vivo use, 4% DMSO+30% PEG 300+5% Tween 80+ddH2O up to 1mg/mL. It is a clear solution.

  • 问题 2:

    Previous aliquots were clear and colorless while this time, it becomes yellow when the powder was dissolved in DMSO? Could you advice on this?

  • 回答:

    Slight color variation due to different processing is normal and usually doesn't interfere with the function.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID