NU7441 (KU-57788)

目录号:S2638

NU7441 (KU-57788) Chemical Structure

Molecular Weight(MW): 413.49

NU7441 (KU-57788)是一种高度有效的,选择性DNA-PK抑制剂,在无细胞试验中IC50为14 nM,也会抑制PI3K,IC50为5 μM。它可降低NHEJ的频率,而增强Cas9介导DNA剪接后发生的同源重组修复率。

规格 价格 库存 购买数量  
RMB 565.91 现货
RMB 974.57 现货
RMB 3040.41 现货
RMB 7928.18 现货
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客户使用Selleck该产品发表文献25篇:

客户使用该产品的6个实验数据:

  • Cells were treated with cisplatin under the following conditions: pretreatment with Nu7026 (Nu7026, 26) or Nu7441 (Nu7441, 41). Before DNA damage, wortmannin was applied at 100 nM for 30 min, Nu7026 at 10 uM for 1 h, Nu7441 at 1 uM for 1 h. Accompanying quantifications of the adjusted nucleolar EU fluorescence are shown. Each condition was normalized to cells treated with DMSO or indicated inhibitors without DNA damaging treatment. Two-way ANOVA was followed by Holm-Sidak's test for the comparison of cells with and without inhibitors. *, **, *** represent P ≤ 0.05, 0.01, 0.001, respectively.

    Nucleic Acids Res 2013 41(15), 7378-86. NU7441 (KU-57788) purchased from Selleck.

    Confocal immunostaining of S2056 phosphorylation of DNA-PKcs following radiation in HEK 293T and p18CycE-expressing cells.

    Nucleic Acids Res 2013 41, 10157-69. NU7441 (KU-57788) purchased from Selleck.

  • (C) Microirradiation live-cell microscopy of U2OS cells stably expressing mEGFP-MacroD2 full-length construct and treated with KU55933 10 μM, VE-821 1 μM, NU7441 1 μM or DMSO. Scale bar, 10 μm.

    Nucleic Acids Res, 2017, 45(1):244-254. NU7441 (KU-57788) purchased from Selleck.

    (C) Immunohistochemically detection of Cleaved Caspase-3 48 h after treatment to measure apoptosis in vivo, induced levels of apoptosis in xenografts treated with radiation in combination with DNA-PKcsi and HT compared to radiation alone. Necrotic areas were observed in xenograft of triple treatment. DNA-PKcsi:NU7441

    Oncotarget, 2016, 7(40): 65504-65513. NU7441 (KU-57788) purchased from Selleck.

  • Validation of activity and specificity of chemical inhibitors of; ATM, ATR, and DNAPK. H460 cells were treated with 1 uM camptothecin (CPT) or 20 ug/ml bleomycin for 1 h in the presence of the indicated inhibitors: DNAPK-i1—NU7026, DNAPK-i2—NU7441. MSH6, fibrillarin, and tubulin were used as loading controls.Effects of DNAPK inhibitors on its autophosphorylation in bleomycin-treated cells.

    Toxicol Sci 2014 10.1093/toxsci/kfu207. NU7441 (KU-57788) purchased from Selleck.

    After starved in serum-free medium for 24h,A549 cells incubated with the indicated concentrations of NU-7441 for 3h,followed by 20-minute stimolation of 100ng/ml EGF.

    Dr. Zhang of Tianjin Medical University. NU7441 (KU-57788) purchased from Selleck.

产品安全说明书

DNA-PK抑制剂选择性比较

生物活性

产品描述 NU7441 (KU-57788)是一种高度有效的,选择性DNA-PK抑制剂,在无细胞试验中IC50为14 nM,也会抑制PI3K,IC50为5 μM。它可降低NHEJ的频率,而增强Cas9介导DNA剪接后发生的同源重组修复率。
靶点
DNA-PK [1]
(Cell-free assay)
14 nM
体外研究

NU7441抑制DNA依赖性蛋白激酶 (DNA-PK) 比抑制其他PI3K相关激酶 (PIKK)家族成员选择性高,IC50 为14 nM。[1] 电离辐射诱导或Etoposide诱导 DNA 损伤后,1 μM NU7441提高γH2AX病灶的持久性。NU7441 浓度为 0.5 μM 或 1 μM时,作用于SW620 和 LoVo细胞,显著提高电离辐射,Etoposide, 和 Doxorubicin 诱导的G2-M累积增多。[2] NU7441浓度为1 μM时,引起 Doxorubicin和电离辐射诱导的DNA双链断裂的持久性,也稍微降低同源重组活性 DNA-PK充足的 M059-Fus-1和 DNA-PK缺陷的 M059 J人类肿瘤细胞。[3] NU7441浓度为 10 μM 时,作用于缺乏和表达polη的细胞,抑制UV诱导 RPA p34过度磷酸化。[4] NU7441 浓度为1 μM时,作用于慢性淋巴细胞性白血病细胞。提高Fludarabine诱导的γH2AX病灶水平,也相应地降低Fludarabine诱导的细胞死亡。[5] NU7441浓度为 1 μM时,作用于慢性淋巴细胞性白血病细胞,抑制Mitoxantrone诱导的DNA-PKcs自磷酸化和修复。[6]它可降低NHEJ的频率,而增强Cas9介导DNA剪接后发生的同源重组修复率 [7]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1770 NULtS4VCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml\VTWM2OD1yLkCyNVQ{KM7:TR?= MXnTRW5ITVJ?
A172 M1zkSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mnq1TWM2OD1yLkG1N|E3KM7:TR?= MnL0V2FPT0WU
NCI-H526 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX;jdHBvUUN3ME2wMlI5PDB5IN88US=> NFriSXVUSU6JRWK=
HDLM-2 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml;6TWM2OD1yLkOyN|Q2KM7:TR?= M164dnNCVkeHUh?=
HuO-3N1 MorNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWXJR|UxRTBwNE[2N|Yh|ryP MYXTRW5ITVJ?
NCI-SNU-1 M2DHc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M375cmlEPTB;MD62NFk6PCEQvF2= MnTjV2FPT0WU
SK-N-AS M2fNSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NITaWWFKSzVyPUCuOlIzOTZizszN NGG0XIRUSU6JRWK=
LoVo NV7KOINUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVj0V5hkUUN3ME2wMlg3PzR7IN88US=> MnTiV2FPT0WU
LAMA-84 M13teWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYTqV|dvUUN3ME2wMlk5QDN|IN88US=> NGn4TG5USU6JRWK=
CTB-1 M2XuTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUnpUZJbUUN3ME2xMlEyPTR4IN88US=> MmX3V2FPT0WU
KP-N-YS NXnjNpVNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnrZTWM2OD1zLkG0NlMyKM7:TR?= M{jnOnNCVkeHUh?=
HH Ml\SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUnJR|UxRTFwMUiwPVMh|ryP NUX5PZRQW0GQR1XS
CHL-1 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV3KO2E6UUN3ME2xMlIyOzZ6IN88US=> M3K4dHNCVkeHUh?=
NB7 NI\ESZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mon1TWM2OD1zLkK0O|Q2KM7:TR?= NVLSUZZoW0GQR1XS
HL-60 MmTpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUXBW3FXUUN3ME2xMlM5OTlizszN NXT2fFRzW0GQR1XS
639-V MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX3JR|UxRTFwNESxNlgh|ryP M{PjV3NCVkeHUh?=
NCI-H1793 NI\XenpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWPJR|UxRTFwNEW4OEDPxE1? M2jmeHNCVkeHUh?=
NEC8 M36w[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV\JR|UxRTFwNUWzOUDPxE1? MVvTRW5ITVJ?
PA-1 M3zle2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUX1SYhTUUN3ME2xMlU5Ojl2IN88US=> Mlf0V2FPT0WU
D-423MG MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUjJR|UxRTFwNkmzOlEh|ryP M3PZOHNCVkeHUh?=
NCI-H292 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUfJR|UxRTFwN{SwNVMh|ryP Mk\sV2FPT0WU
SK-MEL-1 NHvQbFhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2HkNmlEPTB;MT63PVQ4QSEQvF2= MUjTRW5ITVJ?
LB2241-RCC MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIG1cFlKSzVyPUKuNVQyPDZizszN MXzTRW5ITVJ?
SK-MEL-3 M{TpWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlziTWM2OD1{LkG2OFkh|ryP MWPTRW5ITVJ?
MHH-PREB-1 NFLGW|RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4fSNWlEPTB;Mj6xOlYxQSEQvF2= MoLNV2FPT0WU
BFTC-905 Ml3TS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWnJR|UxRTJwMU[2PFch|ryP M4WzSnNCVkeHUh?=
Ramos-2G6-4C10 NWqwfWY{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHLzclRKSzVyPUKuNVk6ODlizszN M2K5VnNCVkeHUh?=
G-361 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M37D[mlEPTB;Mj6yNVY5KM7:TR?= MUTTRW5ITVJ?
MOLT-4 NES5eVRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYftSmZ4UUN3ME2yMlIyQDh6IN88US=> NH7pNnlUSU6JRWK=
DEL NHrsU5VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2HuZ2lEPTB;Mj6zOVU3PCEQvF2= MXvTRW5ITVJ?
MV-4-11 NHTtcJpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHzuWm5KSzVyPUKuN|c{QSEQvF2= NH3n[5hUSU6JRWK=
SK-NEP-1 MlqxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoHMTWM2OD1{LkO4O|g{KM7:TR?= NYrENFVTW0GQR1XS
RS4-11 NEiye3lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF3EcnVKSzVyPUKuOVYxOjNizszN MV;TRW5ITVJ?
HuH-7 NFr6[5VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mk\pTWM2OD1{LkW2O|AzKM7:TR?= Mm\nV2FPT0WU
A101D MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFnFNGtKSzVyPUKuOlE{OzhizszN M3\t[HNCVkeHUh?=
KG-1 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUHPdlZFUUN3ME2yMlY4QTJ2IN88US=> Mmq3V2FPT0WU
KALS-1 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4nDe2lEPTB;Mj62PVY{OyEQvF2= NH7NPGVUSU6JRWK=
VMRC-RCZ MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV;xcJhXUUN3ME2yMlc4OzJ6IN88US=> MXvTRW5ITVJ?
SK-UT-1 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlGwTWM2OD1|LkG1N|Eh|ryP MnjCV2FPT0WU
SW962 M1W2Umdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGj3WFZKSzVyPUOuNlA{PTJizszN M1PSfXNCVkeHUh?=
DBTRG-05MG M2e3fWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX64d4dzUUN3ME2zMlI5ODh3IN88US=> NHi5Z4FUSU6JRWK=
PANC-08-13 NYrlcZJUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXTJR|UxRTNwNEGyO|gh|ryP NGDNVoVUSU6JRWK=
QIMR-WIL MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlLZTWM2OD1|LkSxN|QyKM7:TR?= NYWwR4Q2W0GQR1XS
SK-MEL-30 MmjsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4jxS2lEPTB;Mz60NlU6QCEQvF2= MnTEV2FPT0WU
697 MnXaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHvQdIxKSzVyPUOuOFQ6QTNizszN M4n1bnNCVkeHUh?=
NY MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MU\JR|UxRTNwNEWwNlIh|ryP MlXLV2FPT0WU
ES7 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NELVSHhKSzVyPUOuOFY4OjlizszN MmXkV2FPT0WU
JVM-3 M2KwNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2DJcGlEPTB;Mz60PFA4PyEQvF2= NVK1NJRWW0GQR1XS
U031 MljJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NG\BboxKSzVyPUOuOVk{PjhizszN M1yzWnNCVkeHUh?=
BHT-101 NGP6PHRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1;afGlEPTB;Mz61PVk5PSEQvF2= NWHuXpp[W0GQR1XS
8305C MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlLlTWM2OD1|Lk[xO|M3KM7:TR?= NHXBVZRUSU6JRWK=
MG-63 NF;jSGZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmHKTWM2OD1|Lk[yOlc3KM7:TR?= MWDTRW5ITVJ?
NOS-1 M2jRSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{i5VmlEPTB;Mz62OVMyOiEQvF2= MXLTRW5ITVJ?
YH-13 NUjIflB6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUjkRlFFUUN3ME2zMlg4OTh7IN88US=> NYWwVHlCW0GQR1XS
LXF-289 MljFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml6wTWM2OD1|LkmxNFQyKM7:TR?= M3HM[XNCVkeHUh?=
GOTO MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVGzXo4{UUN3ME2zMlkyPDlizszN NGDDU4JUSU6JRWK=
EKVX M3n4bWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MorzTWM2OD12LkKyOVI1KM7:TR?= NUPQOYsyW0GQR1XS
CAL-51 NWLvcHN6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGqwfpVKSzVyPUSuNlQ5PTRizszN NUTtN5V5W0GQR1XS
AN3-CA M1;vZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYPJR|UxRTRwMkW4NVMh|ryP MlzCV2FPT0WU
IA-LM M1X2[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mk[yTWM2OD12LkK3PVM2KM7:TR?= M1HCcXNCVkeHUh?=
KU-19-19 M2PnWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGnkRpNKSzVyPUSuN|I6OjFizszN MXPTRW5ITVJ?
A704 NHjTZolIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2mySmlEPTB;ND60NFg5QCEQvF2= NI[wVZRUSU6JRWK=
RH-18 NH71coFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnX4TWM2OD12LkS0PVU{KM7:TR?= MVvTRW5ITVJ?
IST-MEL1 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV;nbWJqUUN3ME20MlU5OjZ|IN88US=> NHLObY9USU6JRWK=
LU-134-A NH3lR2JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEnJ[|lKSzVyPUSuOVk3QDVizszN MnG5V2FPT0WU
SF126 NFOwdm5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUXJR|UxRTRwNkC3NVUh|ryP MkfFV2FPT0WU
EFO-27 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1HCXmlEPTB;ND62OlUzPSEQvF2= NF\2WGZUSU6JRWK=
SN12C NFPRT4JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1jv[2lEPTB;ND63NVg6QCEQvF2= M{[3XXNCVkeHUh?=
L-363 NFXleXVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MljQTWM2OD12Lke3NVE3KM7:TR?= Mn3RV2FPT0WU
MEL-HO NF;2WnJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVzJR|UxRTRwN{e5PFkh|ryP MWfTRW5ITVJ?
TYK-nu MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWjIeJpsUUN3ME20MlgxOTJ6IN88US=> MnrsV2FPT0WU
MDA-MB-415 NF7DXG5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIi0SJpKSzVyPUWuNFA{OTRizszN M333[nNCVkeHUh?=
HCC70 Mm\BS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3j0R2lEPTB;NT6wN|k{QSEQvF2= MWPTRW5ITVJ?
IGROV-1 M4i4dmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkPhTWM2OD13LkK1NlkzKM7:TR?= Mo\YV2FPT0WU
NCI-H1355 NYDZdJFKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoDSTWM2OD13LkK5OkDPxE1? NI[xXJJUSU6JRWK=
23132-87 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkjhTWM2OD13LkOyNFI1KM7:TR?= M3LnZXNCVkeHUh?=
NB69 NWf1V3ZqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH75[ZhKSzVyPUWuN|I1OiEQvF2= NX:0TGF3W0GQR1XS
HSC-2 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFm2bGRKSzVyPUWuOFE4PzNizszN NXf2enFNW0GQR1XS
KYSE-410 NEjFOmdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH7Ic5VKSzVyPUWuOFc3OzZizszN NVizO2JOW0GQR1XS
GCIY NI\PNGhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYnJR|UxRTVwNUGzO|gh|ryP NEfiSmlUSU6JRWK=
A427 NXLaXnNjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M17lR2lEPTB;NT61N|Y3OSEQvF2= M1O5[XNCVkeHUh?=
ChaGo-K-1 NGH4ZYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX;JRW9MUUN3ME21MlU3PTl7IN88US=> MULTRW5ITVJ?
PFSK-1 MnLUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnmbZlKSzVyPUWuOlIyQTRizszN M1zRcXNCVkeHUh?=
MLMA Ml\BS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3mz[GlEPTB;NT64N|YxPiEQvF2= M{Xxe3NCVkeHUh?=
RVH-421 NFXUOoZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUXxb217UUN3ME22MlA4OzN6IN88US=> MYjTRW5ITVJ?
LB1047-RCC NYjtUI5zT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkCwTWM2OD14LkG3OVIzKM7:TR?= MmHSV2FPT0WU
MHH-NB-11 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGXLdWdKSzVyPU[uN|I4OjFizszN MV;TRW5ITVJ?
J-RT3-T3-5 MmDlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHriR|VKSzVyPU[uOlMzQTFizszN MWDTRW5ITVJ?
UM-UC-3 M3jpOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2npNGlEPTB;Nj62OFM{PCEQvF2= M{fzVHNCVkeHUh?=
IST-SL1 M4H5fGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4LZdGlEPTB;Nj62PVM3QSEQvF2= NILZN|NUSU6JRWK=
NB14 NFvYUZhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVnJR|UxRTZwN{m3OlEh|ryP NV;GeZRDW0GQR1XS
NBsusSR NF\yOXpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NETzNGlKSzVyPU[uPFI2ODJizszN NGDZUlVUSU6JRWK=
D-263MG M1LTOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUXJR|UxRTZwOUGwOlgh|ryP M2TkUHNCVkeHUh?=
NCI-H2347 MlnNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVHJR|UxRTZwOUOyNVMh|ryP NILkbIxUSU6JRWK=
ES8 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MULJR|UxRTZwOUe1PFgh|ryP NFHzO4ZUSU6JRWK=
786-0 Ml7YS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGHiW5RKSzVyPUeuNFk4QDZizszN MUfTRW5ITVJ?
EPLC-272H NUX5XFhwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlGzTWM2OD15LkG2NlQ3KM7:TR?= NULsVVBVW0GQR1XS
CAPAN-1 NY\hWlBNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2X3TmlEPTB;Nz6yOFM2QSEQvF2= M4PFeHNCVkeHUh?=
NCI-H82 Ml3BS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn7STWM2OD15LkK2OlU6KM7:TR?= NIjZXHFUSU6JRWK=
G-402 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF\PPJhKSzVyPUeuN|AxPTFizszN NIP0ZVBUSU6JRWK=
SW982 NU\aPYs1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlfoTWM2OD15LkOwNlA{KM7:TR?= NVW1cHlVW0GQR1XS
OVCAR-4 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIDIZnZKSzVyPUeuN|E{OjhizszN NWDqUFM1W0GQR1XS
KARPAS-299 NGruOYxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Moj2TWM2OD15LkOyOlIzKM7:TR?= MoDMV2FPT0WU
MIA-PaCa-2 NIjj[I5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mnv2TWM2OD15LkO2PFI{KM7:TR?= NXrtbXRHW0GQR1XS
AU565 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1rCcmlEPTB;Nz61PVg{OyEQvF2= M2TUU3NCVkeHUh?=
GAMG MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoXITWM2OD15Lk[0NVMyKM7:TR?= NXHORYx2W0GQR1XS
HuO9 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MknTTWM2OD15LkexO|Q{KM7:TR?= M3;QRnNCVkeHUh?=
ACN NFv0NZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFzS[pBKSzVyPUeuO|Q{OyEQvF2= MYnTRW5ITVJ?
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NKM-1 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2H3RWlEPTB;Nz63OFk2PSEQvF2= M{fWNnNCVkeHUh?=
CAL-12T MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWq0ZlY{UUN3ME23Mlk1OzV{IN88US=> NF7VWWdUSU6JRWK=
FADU MmDHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVHGUGZYUUN3ME24MlA{PjV2IN88US=> M3K0enNCVkeHUh?=
NCI-H28 NWPYNHlDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3zmU2lEPTB;OD6xOlk3OiEQvF2= NITB[o1USU6JRWK=
LCLC-97TM1 NWDyS2NxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUTNSWwxUUN3ME24MlIyOTJ{IN88US=> M1;kcHNCVkeHUh?=
CHP-134 MnXsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV;JR|UxRThwMkSxPFUh|ryP MUTTRW5ITVJ?
HT-1080 NFu4SXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV\JR|UxRThwMkWwPVMh|ryP M3nwenNCVkeHUh?=
PC-3 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHjaO4dKSzVyPUiuNlc{QTJizszN NYTad2VUW0GQR1XS
SNU-449 M1S0PGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVjZPHZ3UUN3ME24MlI4QTNizszN NFHrOINUSU6JRWK=
VA-ES-BJ M4L1dmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2fONGlEPTB;OD6zOFY5PiEQvF2= NFvFOZpUSU6JRWK=
HT MnHTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1PJXGlEPTB;OD6zOlQ6KM7:TR?= NYnCUmptW0GQR1XS
HOS MoK4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml;CTWM2OD16LkO3OVg6KM7:TR?= NIKzb|VUSU6JRWK=
KNS-62 NWLlXok5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkfuTWM2OD16LkO3O|YzKM7:TR?= NVnEe3N4W0GQR1XS
OAW-42 NFPzN4lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYjjXIhOUUN3ME24Mlk2QTZ2IN88US=> NHH6VYdUSU6JRWK=
A549 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3TsdGlEPTB;OT6wPVYyOiEQvF2= M{DXfHNCVkeHUh?=
CAKI-1 M2jDdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWXJR|UxRTlwMU[2NUDPxE1? NWO0ZZF3W0GQR1XS
HCC1937 NIDwOYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX3JR|UxRTlwNkm4OlUh|ryP NWXxSZZKW0GQR1XS
GI-ME-N NFL3RWVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHvRXo5KSzVyPUmuO|AyOzdizszN MUfTRW5ITVJ?
DU-4475 NV7kenh7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnrYTWM2OD17Lkm2PVM6KM7:TR?= NV;Ffm9pW0GQR1XS
EM-2 NFXUR3JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWr6SHdbUUN3ME2xNE4zPDJ4IN88US=> NVnL[VNtW0GQR1XS
NCI-H1755 M36wW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{jyN2lEPTB;MUCuNlQzQCEQvF2= NILuOpJUSU6JRWK=
NCI-H1437 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYjLeZZCUUN3ME2xNE42PzJ3IN88US=> MmLVV2FPT0WU
VM-CUB-1 M3zFUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXr0PHB[UUN3ME2xNE43OTZ2IN88US=> NEXIOFBUSU6JRWK=
A2058 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFLQRWFKSzVyPUGwMlY1ODRizszN NYiyTmx7W0GQR1XS
BPH-1 NXTuTI9TT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml;PTWM2OD1zMD63NVQ2KM7:TR?= NFfJdpBUSU6JRWK=
NB5 M1n6eGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFXIPXZKSzVyPUGwMlc2PTlizszN NF65UIRUSU6JRWK=
G-401 NVyxVoNLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWPjfXpIUUN3ME2xNE44PjJ4IN88US=> MVjTRW5ITVJ?
CAL-72 NFrafVdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3Hyb2lEPTB;MUCuPFA6PCEQvF2= MUfTRW5ITVJ?
SK-MEL-28 MkHqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVWyUXZRUUN3ME2xNE45OjB{IN88US=> NWS3OYR7W0GQR1XS
C32 MmDmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2nxdGlEPTB;MUCuPFM1PyEQvF2= MV7TRW5ITVJ?
NCI-H1155 M4ntbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYfJR|UxRTFyLkizO|Yh|ryP NGrCcIRUSU6JRWK=
BB49-HNC NUC2WJo1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUDlXnFZUUN3ME2xNE45PTh4IN88US=> MnXZV2FPT0WU
GMS-10 NVX6NHd2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{XWcWlEPTB;MUCuPFk4OSEQvF2= NFXG[2xUSU6JRWK=
K5 MkPES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYTJR|UxRTFyLkmwO|Eh|ryP MVrTRW5ITVJ?
OS-RC-2 MknLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYHJR|UxRTFzLkC1OVkh|ryP MVrTRW5ITVJ?
HTC-C3 NY[4UFlTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHLrS49KSzVyPUGxMlA4OTRizszN MoGwV2FPT0WU
LB996-RCC NHz5Z2NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGPadplKSzVyPUGxMlA4OjNizszN M3:2TXNCVkeHUh?=
NCI-H1563 NI\1Tm9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmCxTWM2OD1zMT6xNFEyKM7:TR?= NWnzPXZNW0GQR1XS
CAL-54 MkfnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnjRTWM2OD1zMT60PFEyKM7:TR?= M{TQRXNCVkeHUh?=
WM-115 NHKxeIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVnYVXl3UUN3ME2xNU43QDJ2IN88US=> MXPTRW5ITVJ?
COLO-684 NYTvenR1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml21TWM2OD1zMT63NlY4KM7:TR?= MnzIV2FPT0WU
HOP-62 MonCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTFzLke1NFgh|ryP Mnu4V2FPT0WU
NCI-H650 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFftfHZKSzVyPUGxMlg6PjFizszN NXy5bHlDW0GQR1XS
TE-11 M3LCUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2LKSmlEPTB;MUGuPVMyPSEQvF2= NIK0dYRUSU6JRWK=
COLO-679 NFrZWllIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1\HfWlEPTB;MUGuPVQ3KM7:TR?= MXrTRW5ITVJ?
FTC-133 M2nJR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2XwbmlEPTB;MUKuNFA4PiEQvF2= MUTTRW5ITVJ?
D-283MED NEKwWWFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWPvO2c6UUN3ME2xNk4xPTZ7IN88US=> MoTlV2FPT0WU
SK-PN-DW MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH3JZohKSzVyPUGyMlE6ODJizszN NU\vUmFvW0GQR1XS
BALL-1 NGDGeYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Moq4TWM2OD1zMj6yOlYzKM7:TR?= M4i4XnNCVkeHUh?=
GT3TKB NUX2XoNsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYX2VmlDUUN3ME2xNk4{ODd2IN88US=> MVLTRW5ITVJ?
HOP-92 NHe2XIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUTJR|UxRTF{LkWyN|Mh|ryP NWHwPXlvW0GQR1XS
M14 MoDSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX3NeGtOUUN3ME2xN{4xOzN3IN88US=> NYfNOppMW0GQR1XS
SKG-IIIa MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4G1O2lEPTB;MUOuNFU2PCEQvF2= MYXTRW5ITVJ?
Becker NYDXdWdZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX;WXoJwUUN3ME2xN{4xPThizszN NWHa[404W0GQR1XS
ES5 NVTDd4FQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXvJR|UxRTF|LkGzOVYh|ryP M{jYSHNCVkeHUh?=
NCI-H2030 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1\0dmlEPTB;MUOuNlA3OiEQvF2= NX3T[|hFW0GQR1XS
SNU-423 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGnpRZZKSzVyPUGzMlM5OSEQvF2= MU\TRW5ITVJ?
CP50-MEL-B MoK2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2LydmlEPTB;MUOuOlI{OiEQvF2= NEHjc21USU6JRWK=
NCI-H1092 Mmr3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFLEWIxKSzVyPUGzMlc1PzVizszN M1HIWHNCVkeHUh?=
8-MG-BA MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF\0c29KSzVyPUGzMlc2OTNizszN M{jV[HNCVkeHUh?=
CAL-27 NWe0OllmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2LxSmlEPTB;MUSuNFczPyEQvF2= MknoV2FPT0WU
AGS MmT2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1q2TWlEPTB;MUSuNVMyQSEQvF2= M4HHbnNCVkeHUh?=
MZ2-MEL NEKwS|NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlvkTWM2OD1zND6xOFg5KM7:TR?= NHPZVVlUSU6JRWK=
BFTC-909 MlnQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mlf2TWM2OD1zND61NFU2KM7:TR?= NXLnZldZW0GQR1XS
D-566MG MlnkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{LyRWlEPTB;MUSuO|cxPiEQvF2= MUnTRW5ITVJ?
MZ7-mel Ml3US5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTF3LkGwOlch|ryP M3zFcXNCVkeHUh?=
TE-5 MmHOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYG4c2xbUUN3ME2xOU4zOzN|IN88US=> MnrNV2FPT0WU
647-V NWjJOmJvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4HsdGlEPTB;MUWuNlcxPSEQvF2= MVrTRW5ITVJ?
DMS-114 NEjDdJhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXrJR|UxRTF3LkOyPVEh|ryP M{LTWXNCVkeHUh?=
ME-180 M4DQNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MU\JR|UxRTF3LkS3PFMh|ryP MUnTRW5ITVJ?
MS-1 NFXiTXVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHjuOGZKSzVyPUG1MlU3OjNizszN M165XnNCVkeHUh?=
NUGC-3 M2O5fGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV\BPYNHUUN3ME2xOU43OjR3IN88US=> NUC2[4UzW0GQR1XS
GB-1 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MW\JR|UxRTF3Lk[0N|ch|ryP MUDTRW5ITVJ?
LOXIMVI NULGdYFOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4HKO2lEPTB;MUWuPFkyQSEQvF2= M2XvZXNCVkeHUh?=
NCI-H1304 NVP5[4NTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3zLNmlEPTB;MUWuPFkzQCEQvF2= NVnYWndGW0GQR1XS
KURAMOCHI MljZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVLTeWFrUUN3ME2xOU46PzFizszN Mk\HV2FPT0WU
SW1783 NWXjPG42T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoDkTWM2OD1zNj6wPVk{KM7:TR?= NX;kcI9LW0GQR1XS
EGI-1 MlXwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWTJR|UxRTF4LkWzOlUh|ryP NIPydnBUSU6JRWK=
KGN M2SySWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWXJR|UxRTF4LkW1PFYh|ryP M37VNnNCVkeHUh?=
PANC-03-27 M3iyOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHjSUYhKSzVyPUG2Mlc3PjJizszN MkXtV2FPT0WU
RH-1 NF7MT3ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUTldYkzUUN3ME2xOk45OjVizszN MVnTRW5ITVJ?
HT-1376 NF7rRYxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4TzVmlEPTB;MU[uPFQ1PiEQvF2= NH3LZ5pUSU6JRWK=
ZR-75-30 M4S4Zmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmnpTWM2OD1zNj65N|YyKM7:TR?= NVfMd2I4W0GQR1XS
TI-73 MlTQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXHTN2h6UUN3ME2xOk46PDB6IN88US=> MnW2V2FPT0WU
TK10 NYG4fFRZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnL3TWM2OD1zNz6wNFc6KM7:TR?= M3HqeHNCVkeHUh?=
SW684 Mm\LS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVXJR|UxRTF5LkCxOVQh|ryP M4TmUnNCVkeHUh?=
RPMI-8866 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mk\vTWM2OD1zNz6wOlk6KM7:TR?= MnLrV2FPT0WU
LNCaP-Clone-FGC MlXpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUC2NngxUUN3ME2xO{42OjBzIN88US=> MUPTRW5ITVJ?
NCI-H2291 M{Oy[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3LhV2lEPTB;MUiuOFM1PSEQvF2= MmToV2FPT0WU
T47D NE\6NFBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3HBVmlEPTB;MUiuOFg5KM7:TR?= MXPTRW5ITVJ?
A204 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4riPGlEPTB;MUiuOVQ2OiEQvF2= MX3TRW5ITVJ?
HT-144 MlrzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUPJR|UxRTF6Lke0Nlch|ryP MmG2V2FPT0WU
MDA-MB-361 MoTHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX61fVdYUUN3ME2xPU4xPzF2IN88US=> M33qU3NCVkeHUh?=
HCC1806 NH3Xe5pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYm2eW8yUUN3ME2xPU4yPTlzIN88US=> NH\3NotUSU6JRWK=
NCI-H596 MmLXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUjJR|UxRTF7Lk[zPVEh|ryP M2\3XnNCVkeHUh?=
K-562 NXzNR40xT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mm\yTWM2OD1zOT64PVI3KM7:TR?= M4TPb3NCVkeHUh?=
D-336MG NYfzT4Z1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mlr4TWM2OD1zOT65N|IzKM7:TR?= MVLTRW5ITVJ?
SK-MEL-2 M1K2Vmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWrJR|UxRTJyLkG1OVkh|ryP MkTaV2FPT0WU
HEC-1 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NG\ERZRKSzVyPUKwMlQ6PzhizszN NH\2VHlUSU6JRWK=
EW-13 NVPkU29{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWLJR|UxRTJyLkW0OFMh|ryP M{K5[nNCVkeHUh?=
Hs-578-T NIHQellIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWHJR|UxRTJyLkW1PFMh|ryP NGfuVVRUSU6JRWK=
SJSA-1 M1fvdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEW2T4hKSzVyPUKwMlU3QDhizszN M4nVWnNCVkeHUh?=
RCC10RGB MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYn6UVZFUUN3ME2yNE43PzF7IN88US=> MVfTRW5ITVJ?
LAN-6 NF;WS41Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn3XTWM2OD1{MT6wN|k3KM7:TR?= MYTTRW5ITVJ?
NCI-H1048 NFOye2lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml7yTWM2OD1{MT6yNlU5KM7:TR?= M3rhTnNCVkeHUh?=
CW-2 MljuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4nEOmlEPTB;MkGuNlcxPSEQvF2= NWPzV2NrW0GQR1XS
HCC2157 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGLYdoRKSzVyPUKxMlM3KM7:TR?= MWHTRW5ITVJ?
EW-22 MljJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4LNWmlEPTB;MkGuN|c3KM7:TR?= M{HrfnNCVkeHUh?=
A253 M4LJU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWOwSollUUN3ME2yNU41PDhzIN88US=> NYjjd|ZmW0GQR1XS
BE-13 M2f2Xmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYPJR|UxRTJzLk[xNVMh|ryP NGCzS2JUSU6JRWK=
KINGS-1 NGPtXG9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYPJR|UxRTJzLk[zNVYh|ryP NHjtZ2xUSU6JRWK=
ETK-1 MmrSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWjwU4hRUUN3ME2yNU45OTV{IN88US=> MUnTRW5ITVJ?
NCI-H2452 MlLRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkHYTWM2OD1{MT64OlQ4KM7:TR?= MXLTRW5ITVJ?
HPAF-II M160cGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYLrb2dbUUN3ME2yNU45QTJ|IN88US=> MlvVV2FPT0WU
D-542MG NEnm[YxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NY\tSHViUUN3ME2yNU46ODZ7IN88US=> MoHoV2FPT0WU
NCI-H630 NGnubZpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmToTWM2OD1{Mj6wNlk3KM7:TR?= MmfWV2FPT0WU
TGBC11TKB NH3MTlNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NECzbodKSzVyPUKyMlA1QSEQvF2= NYHxcphbW0GQR1XS
BCPAP MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmrMTWM2OD1{Mj62NVEh|ryP MlnJV2FPT0WU
HLE M1P4TGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXnJR|UxRTJ{Lk[5O{DPxE1? NWXNOo9NW0GQR1XS
NCI-H727 M3Xte2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXfLV4tJUUN3ME2yNk44OzVizszN NXT3O49UW0GQR1XS
RD MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV3sSGdUUUN3ME2yNk44PTF6IN88US=> NYrPbI9HW0GQR1XS
NCI-H522 M{jNNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3f5XGlEPTB;MkKuPFQ{OSEQvF2= NGK3XXBUSU6JRWK=
CGTH-W-1 NF3ZZnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn6yTWM2OD1{Mz6wOlQyKM7:TR?= M2K2bXNCVkeHUh?=
SK-LU-1 M1vEO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGr0N5BKSzVyPUKzMlQ3QDNizszN NYKyZnJJW0GQR1XS
BB65-RCC M33COGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn7TTWM2OD1{Mz63PFY{KM7:TR?= NGj3UoFUSU6JRWK=
HSC-3 M{PhSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFrOXYpKSzVyPUKzMlg2OjdizszN NUjFUHV7W0GQR1XS
SK-MES-1 NWLqNWwxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mmq2TWM2OD1{ND6wNVYyKM7:TR?= M2[ycHNCVkeHUh?=
DB MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmXoTWM2OD1{ND6xNFI5KM7:TR?= NVvieY56W0GQR1XS
HO-1-N-1 NWrpbHNTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1e5V2lEPTB;MkSuN|A6OyEQvF2= M2fWc3NCVkeHUh?=
MKN1 NFfJOFZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVPaUVJjUUN3ME2yOE43QCEQvF2= NUXyXmhiW0GQR1XS
MN-60 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVHJR|UxRTJ2Lki1NVkh|ryP MnjQV2FPT0WU
8505C M{PqVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2DlOGlEPTB;MkWuNVg1PSEQvF2= Mm\4V2FPT0WU
COLO-320-HSR NXf6enQzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{T0N2lEPTB;MkWuNlIxQCEQvF2= M{T2XHNCVkeHUh?=
BB30-HNC MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mkj5TWM2OD1{NT6yOFg{KM7:TR?= NHPmVWNUSU6JRWK=
KM12 NWXoWpNET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NILqZXhKSzVyPUK1MlU5ODdizszN NUTKOXZ3W0GQR1XS
NB13 MmTSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVXJR|UxRTJ3LkW4PVgh|ryP M17MTXNCVkeHUh?=
HCC2998 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGXkRYFKSzVyPUK2MlAzQDNizszN NVy3bpVNW0GQR1XS
U-118-MG NV23fW9{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mmq5TWM2OD1{Nj6wPFA5KM7:TR?= NX\3SJVuW0GQR1XS
NB10 MoTZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{HoVmlEPTB;Mk[uNlM1KM7:TR?= MoLLV2FPT0WU
SK-LMS-1 M1XHVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV75[YF[UUN3ME2yO{4xPzB2IN88US=> MnP6V2FPT0WU
SW1573 NIK2PG9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHfT[WRKSzVyPUK3MlEyKM7:TR?= MXLTRW5ITVJ?
LB373-MEL-D MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWPJR|UxRTJ5LkGyPVQh|ryP MVHTRW5ITVJ?
DK-MG MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVjJR|UxRTJ5LkG4NVch|ryP MlHKV2FPT0WU
RMG-I M4\pfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUTJR|UxRTJ5LkKwNlkh|ryP NFW1V4RUSU6JRWK=
SW1088 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXjJR|UxRTJ5LkWwOFIh|ryP NHrOb4VUSU6JRWK=
SK-OV-3 M4D3S2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4XyNGlEPTB;MkeuO|U6OyEQvF2= NX7O[VNoW0GQR1XS
KP-N-YN NGPVUYVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmDGTWM2OD1{Nz64NFQ{KM7:TR?= NI\OWoZUSU6JRWK=
RPMI-7951 M3f1NWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVLJR|UxRTJ6LkK0OVYh|ryP NIHEXHJUSU6JRWK=
CaR-1 NVnve2o4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{TadWlEPTB;MkiuOVU5OiEQvF2= MXvTRW5ITVJ?
MKN7 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{TYPWlEPTB;MkiuOVk3PCEQvF2= NUWwOo5[W0GQR1XS
CHP-212 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGf2eFJKSzVyPUK4Mlc1ODFizszN MUTTRW5ITVJ?
KYSE-450 NV3rSG5GT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFrCZ4pKSzVyPUK4MlgxQTFizszN Mom2V2FPT0WU
RXF393 NGnkOHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXXJR|UxRTJ7LkK5NFYh|ryP NF\mN4hUSU6JRWK=
P30-OHK NU\DV5NsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVTvd3NPUUN3ME2yPU4{ODR6IN88US=> M1vBSHNCVkeHUh?=
Ca9-22 NFvqW|hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEPuW49KSzVyPUK5MlQzQTlizszN MWjTRW5ITVJ?
RT-112 NXPhRVNtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUm5dmZLUUN3ME2yPU41PjFzIN88US=> MoDyV2FPT0WU
ES1 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXPJR|UxRTJ7Lki1OFQh|ryP NYPXdHRSW0GQR1XS
HCE-4 NUTyfZlxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXjJR|UxRTJ7Lki3PFYh|ryP MlvuV2FPT0WU
AM-38 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3GxOWlEPTB;M{CuNFYxPiEQvF2= NYH2codrW0GQR1XS
AsPC-1 NWfP[IhXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX7JR|UxRTNyLkiwOVMh|ryP M1fFSXNCVkeHUh?=
TE-9 NV71N49lT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHu0fINKSzVyPUOwMlg4OzdizszN NGHYb2hUSU6JRWK=
HuP-T4 NHXSbYlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWmzO2QyUUN3ME2zNE46PjN6IN88US=> NGXTdHRUSU6JRWK=
LB2518-MEL MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWfJR|UxRTNzLkC3OFQh|ryP M{TUcnNCVkeHUh?=
NCI-H1703 MmrpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkLGTWM2OD1|MT6wPVA2KM7:TR?= MVTTRW5ITVJ?
NCI-H2228 M2XnVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NY\5OWlmUUN3ME2zNU41PjVzIN88US=> MXjTRW5ITVJ?
SCC-4 M3TwXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3fnOWlEPTB;M{GuPVE5OSEQvF2= NIPZTYJUSU6JRWK=
KNS-81-FD NEOxS2dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlyzTWM2OD1|Mj6wNVI5KM7:TR?= NE\MXFJUSU6JRWK=
NTERA-S-cl-D1 M3Xubmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXnJR|UxRTN{LkC3N|kh|ryP MX7TRW5ITVJ?
Daoy MmexS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn3MTWM2OD1|Mj6wPFM5KM7:TR?= NHv5cXNUSU6JRWK=
ES4 M33he2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWHXWGhLUUN3ME2zNk4{QTJ{IN88US=> NH2w[mhUSU6JRWK=
MHH-ES-1 MkDPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV\sfGQ3UUN3ME2zNk41QDd{IN88US=> M3TvT3NCVkeHUh?=
C-33-A NF\VPJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUjGZpVQUUN3ME2zNk44PzJ6IN88US=> MUTTRW5ITVJ?
BHY MnjOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYDJR|UxRTN{Lkm0PVUh|ryP MXTTRW5ITVJ?
Detroit562 M3\mZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2O3UGlEPTB;M{OuOlY2PyEQvF2= NF;wb2VUSU6JRWK=
EW-1 NYHacHNyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEK2WFJKSzVyPUOzMlk{OjJizszN M{\jO3NCVkeHUh?=
NCI-H1395 MnXUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFKzRYpKSzVyPUO0MlA4QTlizszN NXvpRYg4W0GQR1XS
KM-H2 M4i3RWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mk\OTWM2OD1|Nj60O|Q{KM7:TR?= MlHnV2FPT0WU
NCI-H520 NV\3T48yT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnLuTWM2OD1|Nj63OVQyKM7:TR?= Mny0V2FPT0WU
D-392MG MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGKx[5hKSzVyPUO3MlM{PDRizszN M4nLUHNCVkeHUh?=
NOMO-1 NHLab4hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUnONlQ3UUN3ME2zO{45ODh7IN88US=> M{nmfHNCVkeHUh?=
TE-6 Ml34S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGezNo1KSzVyPUO4MlEzPCEQvF2= MkLkV2FPT0WU
HT-3 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVzOcnhKUUN3ME2zPE41PDN4IN88US=> NXvndpNRW0GQR1XS
RPMI-8226 M3[zO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnjXTWM2OD1|OD65OVE6KM7:TR?= M4\lSXNCVkeHUh?=
U251 M4LEe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXjJR|UxRTN7LkCxNlQh|ryP M3zm[HNCVkeHUh?=
GCT MmHLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF3TemxKSzVyPUO5MlE5PTJizszN M{DydXNCVkeHUh?=
A431 NEDEcWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVj3cphrUUN3ME2zPU4yQDl2IN88US=> NFvDNpBUSU6JRWK=
TE-12 MkDWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGrSTIVKSzVyPUO5MlI1PDhizszN NHLuNWVUSU6JRWK=
HMV-II MoTMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVzK[IRuUUN3ME2zPU42ODR5IN88US=> NVzVfo1PW0GQR1XS
IST-MES1 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWLJR|UxRTRyLkG1NFIh|ryP MUHTRW5ITVJ?
SW13 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3vn[mlEPTB;NECuOVE6KM7:TR?= Mn\vV2FPT0WU
SF295 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYjYR4hGUUN3ME20NE45ODZ4IN88US=> NFG5VWNUSU6JRWK=
MDA-MB-157 M3;OeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1XGdGlEPTB;NECuPVQ3OiEQvF2= MWnTRW5ITVJ?
TE-1 MmLXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXnFfZpWUUN3ME20NU45PzF2IN88US=> M37Nb3NCVkeHUh?=
HuCCT1 Mmq1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX7JR|UxRTR{LkWyPFkh|ryP M1;iSHNCVkeHUh?=
KYSE-510 Mn;PS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1f3[WlEPTB;NEOuNVc2PCEQvF2= NV:ycJNmW0GQR1XS
NCI-H358 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWXtcFNVUUN3ME20OE4xOzB2IN88US=> NXvSfos3W0GQR1XS
SW900 NGryd3VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVjJR|UxRTR2LkC3OVgh|ryP MlrBV2FPT0WU
CAS-1 M3:yOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoC1TWM2OD12ND6wPVkyKM7:TR?= NFzVbHRUSU6JRWK=
TE-8 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWfJR|UxRTR2LkW2OVgh|ryP MVHTRW5ITVJ?
P12-ICHIKAWA NX3zd41uT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4O1dmlEPTB;NESuOlEyOiEQvF2= MWLTRW5ITVJ?
YKG-1 M1;JeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn\jTWM2OD12ND63PFEh|ryP MYDTRW5ITVJ?
SNU-C2B MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXzJR|UxRTR2Lke5NFMh|ryP NEHseZJUSU6JRWK=
LCLC-103H NFfvcm5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXjVdI9zUUN3ME20OE45PzB|IN88US=> MU\TRW5ITVJ?
U-87-MG NHXsV29Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2H3W2lEPTB;NEWuNVAzOiEQvF2= Mmr4V2FPT0WU
HAL-01 MnjES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUXJR|UxRTR3LkGzO|kh|ryP MXXTRW5ITVJ?
OVCAR-8 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGrTWlhKSzVyPUS1MlM2PjRizszN M2r5[XNCVkeHUh?=
KYSE-150 M{\nUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NELoZZBKSzVyPUS3MlExPTJizszN NX:2[oI5W0GQR1XS
OE33 NGK4U|dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUXJR|UxRTR5LkG0Nlkh|ryP NUTBNHRoW0GQR1XS
CAL-62 MoLVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXzjNVF{UUN3ME20O{41ODZ6IN88US=> M2\JenNCVkeHUh?=
TCCSUP NX7vR2p3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX;JR|UxRTR5Lk[yOlQh|ryP M4LvdnNCVkeHUh?=
H4 NYPaPXpWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1nZWGlEPTB;NEeuOlYzOSEQvF2= MlfhV2FPT0WU
CP66-MEL NIHxZnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlTsTWM2OD12OD6wO|A1KM7:TR?= M3KzXHNCVkeHUh?=
SNB75 MojQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWfxO3ZFUUN3ME20PE4yQDd2IN88US=> M1;VZXNCVkeHUh?=
Mo-T NVXwVYh5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn\CTWM2OD12OD6yO|kh|ryP MmD1V2FPT0WU
BT-549 NV\YW|dqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFfJd5JKSzVyPUS4MlM4OjlizszN MlnNV2FPT0WU
IGR-1 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1fteGlEPTB;NEiuOlY1PSEQvF2= MWPTRW5ITVJ?
NCI-H1299 M1zNdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF\PfGdKSzVyPUS4MlczPDhizszN M4\KO3NCVkeHUh?=
ALL-PO MlTTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2TJZmlEPTB;NEmuPVI3QCEQvF2= Mnz6V2FPT0WU

... Click to View More Cell Line Experimental Data

体内研究 NU7441按 10 mg/kg剂量腹腔注射处理携带SW620移植瘤的小鼠,按无毒剂量处理至少4小时,然后提高 Etoposide诱导的肿瘤生长延迟2倍。 [2]

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

细胞实验:

[2]

+ 展开
  • Cell lines: SW620, LoVo, V3-YAC和 V3细胞
  • Concentrations: 0.5 μM或 1 μM
  • Incubation Time: 17 小时
  • Method:

    通过克隆实验测定NU7441,Etoposide, Doxorubicin, 和电离辐射作用于SW620, LoVo, V3,和 V3-YAC细胞存活的效果。在有或无 NU7441(0.5 或 1.0 μM)存在时,使用Etoposide 或Doxorubicin处理6孔板或6-cm盘中指数生长的细胞16小时。放射增敏研究中, NU7441加到细胞中,1小时后,使用辐射处理。使用γ-射线 (3.1 Gy/min 137Cesium)处理V3和V3-YAC 细胞。使用可用设备,使用X-射线 (2.9 Gy/min at 230 kV, 10 mA) 处理SW620 和 LoVo 细胞。辐射处理后,在有或无NU7441存在时,细胞再温育16小时。胰蛋白酶消化,收集细胞,计数,然后按每盘 100 到105 的密度接种在10-cm 直径的Petri盘中, 盘中含无药物培养基,用于形成集落。使用结晶紫对集落进行染色,10 到 14天后,使用自动集落计数器计数。


    (Only for Reference)
动物实验:

[2]

+ 展开
  • Animal Models: 携带 SW620移植瘤的雌性裸鼠
  • Formulation: 无菌 0.9% NaCl溶液
  • Dosages: 10 mg/kg
  • Administration: 腹腔注射
    (Only for Reference)

溶解度 (25°C)

体外 DMSO 4 mg/mL warmed (9.67 mM)
Water Insoluble
Ethanol Insoluble
体内 从左到右依次将纯溶剂加入产品,现配现用(数据来自Selleck实验检测而非文献):
5% DMSO+30% PEG 300+5% Tween 80+ddH2O
2mg/mL

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 413.49
化学式

C25H19NO3S

CAS号 503468-95-9
稳定性 powder
in solvent
别名 N/A

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

技术支持

在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-668-6834,或者技术支持邮箱tech@selleck.cn,直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题,请给我们留言。

  • * 必填项

常见问题及建议解决方法

  • 问题 1:

    Could you please suggest formulations of the drug for in vivo injection?

  • 回答:

    We tested the following formulation for in vivo use, 4% DMSO+30% PEG 300+5% Tween 80+ddH2O up to 1mg/mL. It is a clear solution.

  • 问题 2:

    Previous aliquots were clear and colorless while this time, it becomes yellow when the powder was dissolved in DMSO? Could you advice on this?

  • 回答:

    Slight color variation due to different processing is normal and usually doesn't interfere with the function.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID