Staurosporine (AM-2282)

For research use only. Not for use in humans.

目录号：S1421 别名： Antibiotic AM-2282, STS 中文名称：星形孢菌素

Staurosporine (AM-2282) Chemical Structure

CAS No. 62996-74-1

Staurosporine (AM-2282, Antibiotic AM-2282, STS)是一种有效的PKC抑制剂，在无细胞试验中作用于PKCα，PKCγ 和PKCη，IC50分别为2 nM，5 nM 和 4 nM，对PKCδ(20 nM)和PKCε(73 nM作用较弱，对PKCζ (1086 nM)的活性很低。同时对其他的激酶PKA, PKG, S6K, CaMKII, 等也显示抑制活性。Phase 3。

规格

价格

库存

购买数量

2mg	RMB 2186.89	现货
5mg	RMB 4095.0	现货
25mg	RMB 12203.1	现货
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客户使用Selleck生产的Staurosporine (AM-2282)发表文献96篇：

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Gastroenterology, 2017, 153(5):1429-1443

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Nat Commun, 2021, 12(1):3636

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Cell Chem Biol, 2021, S2451-9456(21)00303-2

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Front Cell Dev Biol, 2021, 9:698679

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Eur J Med Chem, 2021, 211:113003

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J Cell Physiol, 2021, 10.1002/jcp.30443

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Biochem Biophys Res Commun, 2021, 567:92-98

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STAR Protoc, 2021, 2(2):100391

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Cell Rep, 2021, 34(8):108767

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J Immunother Cancer, 2021, 9(2)e001906

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EMBO J, 2020, 39(5):e102608

PubMed: 31930741 ( click the link to review the publication )

Genes Dev, 2020, 34(7-8):526-543

PubMed: 32079652 ( click the link to review the publication )

Cell Rep, 2020, 10;30(10):3411-3423 e7

PubMed: 32160546 ( click the link to review the publication )

Cell Rep, 2020, 30(11):3864-3874

PubMed: 32187555 ( click the link to review the publication )

EBioMedicine, 2020, 51:102585

PubMed: 31879244 ( click the link to review the publication )

Sci Signal, 2020, 13(623)

PubMed: 32184287 ( click the link to review the publication )

Cancers (Basel), 2020, 12(9)E2668

PubMed: 32962010 ( click the link to review the publication )

Cancers (Basel), 2020, 10;12(6):E1523

PubMed: 32532053 ( click the link to review the publication )

Anal Chem, 2020, 92(1):1363-1371

PubMed: 31794197 ( click the link to review the publication )

Anal Chem, 2020, 10.1021/acs.analchem.0c02756

PubMed: 32933243 ( click the link to review the publication )

FASEB J, 2020, 34(1):1122-1135

PubMed: 31914633 ( click the link to review the publication )

Eur J Med Chem, 2020, 193:112232

PubMed: 32199135 ( click the link to review the publication )
Nephrol Dial Transplant, 2020, gfaa290

PubMed: 33367746 ( click the link to review the publication )

Eur J Immunol, 2020, 10.1002/eji.202048905

PubMed: 33354776 ( click the link to review the publication )

Int J Mol Sci, 2020, 18;21(8):2825

PubMed: 32325639 ( click the link to review the publication )

Sci Rep, 2020, 10(1):18677

PubMed: 33122816 ( click the link to review the publication )

Sci Rep, 2020, 10(1):931

PubMed: 31969633 ( click the link to review the publication )

Molecules, 2020, 25(18)E4318

PubMed: 32967084 ( click the link to review the publication )

Eur J Pharmacol, 2020, 868:172886

PubMed: 31866407 ( click the link to review the publication )

Neoplasia, 2020, 22(10):470-483

PubMed: 32818841 ( click the link to review the publication )

Cell Res, 2020, 1-13

PubMed: 32759968 ( click the link to review the publication )

Cell Rep, 2020, 32(4):107959

PubMed: 32726624 ( click the link to review the publication )

Oncogene, 2020, 10.1038/s41388-020-1382-5

PubMed: 32651460 ( click the link to review the publication )

Mol Cancer Ther, 2020, 19(2):637-649

PubMed: 31784455 ( click the link to review the publication )

Autophagy, 2019, 10.1080/15548627

PubMed: 31251111 ( click the link to review the publication )

Autophagy, 2019, 15(2):295-311

PubMed: 30176161 ( click the link to review the publication )

Br J Pharmacol, 2019, 176(22):4388-4401

PubMed: 30270436 ( click the link to review the publication )

Ther Adv Med Oncol, 2019, 11:1758835919891567

PubMed: 31839810 ( click the link to review the publication )

FASEB J, 2019, 33(8):9062-9074

PubMed: 31180722 ( click the link to review the publication )

Nephrol Dial Transplant, 2019, 34(6):934-941

PubMed: 30189026 ( click the link to review the publication )

Int J Biol Sci, 2019, 15(4):838-846

PubMed: 30906214 ( click the link to review the publication )

Int Immunopharmacol, 2019, 66:146-153

PubMed: 30453148 ( click the link to review the publication )

Methods Mol Biol, 2019, 2054:171-183

PubMed: 31482456 ( click the link to review the publication )

J Org Chem, 2019, 10.1021/acs.joc.9b02414

PubMed: 31858795 ( click the link to review the publication )

Cell Res, 2018, 28(8):833-854

PubMed: 30030520 ( click the link to review the publication )

Nat Commun, 2018, 9(1):4846

PubMed: 30451870 ( click the link to review the publication )
Oncogene, 2018, 37(30):4122-4136

PubMed: 29706657 ( click the link to review the publication )

Oncogene, 2018, 37(11):1485-1502

PubMed: 29321664 ( click the link to review the publication )

Arch Toxicol, 2018, 92(6):2119-2135

PubMed: 29589053 ( click the link to review the publication )

Biochem Pharmacol, 2018, 150:9-23

PubMed: 29338970 ( click the link to review the publication )

Acta Pharmacol Sin, 2018, 39(12):1902-1912

PubMed: 30038340 ( click the link to review the publication )

Analyst, 2018, 143(12):2908-2914

PubMed: 29808847 ( click the link to review the publication )

Mol Carcinog, 2018, 57(7):886-895

PubMed: 29566278 ( click the link to review the publication )

Phytomedicine, 2018, 40:148-157

PubMed: 29496167 ( click the link to review the publication )

Exp Cell Res, 2018, 370(1):103-115

PubMed: 29908160 ( click the link to review the publication )

Virus Res, 2018, 246:55-64

PubMed: 29341877 ( click the link to review the publication )

J Child Adolesc Psychopharmacol, 2018, 28(2):117-123

PubMed: 29161523 ( click the link to review the publication )

Oncotarget, 2018, 9(24):16917-16931

PubMed: 29682194 ( click the link to review the publication )

Oncotarget, 2018, 9(89):35962-35973

PubMed: 30542510 ( click the link to review the publication )

Oncotarget, 2018, 9(32):22254-22268

PubMed: 29854276 ( click the link to review the publication )

Nat Commun, 2017, 1;8(1):1232

PubMed: 29089541 ( click the link to review the publication )

EMBO J, 2017, 36(2):202-212

PubMed: 27852626 ( click the link to review the publication )

Cell Rep, 2017, 20(7):1692-1704

PubMed: 28813679 ( click the link to review the publication )

Anal Chem, 2017, 89(3):1892-1899

PubMed: 28208281 ( click the link to review the publication )

Mol Cancer Ther, 2017, 16(1):57-67

PubMed: 27760835 ( click the link to review the publication )

Mol Cancer Ther, 2017, 16(10):2201-2214

PubMed: 28619755 ( click the link to review the publication )

J Virol, 2017, 91(23)

PubMed: 28904196 ( click the link to review the publication )

Acta Pharmacol Sin, 2017, 38(12):1632-1641

PubMed: 28713162 ( click the link to review the publication )

J Agric Food Chem, 2017, 65(31):6625-6637

PubMed: 28697598 ( click the link to review the publication )

Virology, 2017, 505:91-101

PubMed: 28235685 ( click the link to review the publication )
SLAS Discov, 2017, 22(5):507-515

PubMed: 28324660 ( click the link to review the publication )

Oncotarget, 2017, 8(42):71512-71519

PubMed: 29069723 ( click the link to review the publication )

Eur J Med Chem, 2016, 124:583-607

PubMed: 27614407 ( click the link to review the publication )

Mol Pharm, 2016, 13(11):3724-3735

PubMed: 27653969 ( click the link to review the publication )

J Cancer Res Clin Oncol, 2016, 142(11):2263-73

PubMed: 27576506 ( click the link to review the publication )

PLoS One, 2016, 11(5):e0154932

PubMed: 27183222 ( click the link to review the publication )

Biochem Biophys Res Commun, 2016, 471(4):528-32

PubMed: 26879140 ( click the link to review the publication )

Exp Clin Endocrinol Diabetes, 2016, 1427:419-30

PubMed: 26849668 ( click the link to review the publication )

Oncotarget, 2016, 7(46):74987-74999

PubMed: 27602492 ( click the link to review the publication )

Oncotarget, 2016, 7(27):41488-41504

PubMed: 27166192 ( click the link to review the publication )

Methods Mol Biol, 2016, 1427:419-30

PubMed: 27259939 ( click the link to review the publication )

Mol Cancer, 2015, 14:114

PubMed: 26041471 ( click the link to review the publication )

Mol Cancer, 2015, 14:59

PubMed: 25880778 ( click the link to review the publication )

J Exp Clin Cancer Res, 2015, 34:69

PubMed: 26198850 ( click the link to review the publication )

Cancer Cell Int, 2015, 15:97

PubMed: 26464561 ( click the link to review the publication )

PLoS One, 2015, 10(3):e0119715

PubMed: 25790461 ( click the link to review the publication )

PLoS One, 2015, 10(7):e0134306

PubMed: 26218638 ( click the link to review the publication )

Cancer Res, 2014, 74(23):7090-102

PubMed: 25277525 ( click the link to review the publication )

Cell Rep, 2014, 8(4):1037-48

PubMed: 25127139 ( click the link to review the publication )

Cell Commun Signal, 2013, 11:76

PubMed: 24090154 ( click the link to review the publication )

Am J Physiol Cell Physiol, 2013, 304(9):C895-904

PubMed: 23447036 ( click the link to review the publication )

J Biomol Screen, 2013, 18(4):388-99

PubMed: 23134735 ( click the link to review the publication )

PLoS One, 2012, 7(6):e39679

PubMed: 22768106 ( click the link to review the publication )

J Biomol Screen, 2012, 17(6):813-21

PubMed: 22453235 ( click the link to review the publication )

产品安全说明书

Antineoplastic and Immunosuppressive Antibiotics抑制剂选择性比较

生物活性

产品描述

靶点

PKCα ^[1] (Cell-free assay)	c-Fgr ^[2] (Cell-free assay)	phosphorylase kinase ^[2] (Cell-free assay)	PKCη ^[1] (Cell-free assay)	PKCγ ^[1] (Cell-free assay)	点击更多
2 nM	2 nM	3 nM	4 nM	5 nM	点击更多

体外研究

Staurosporine 也强抑制HeLa S3细胞，IC50为4 nM。^[1]Staurosporine 也抑制多种其他蛋白激酶，包括PKA, PKG, 磷酸激酶, S6 激酶, 肌球蛋白轻链激酶(MLCK), CAM PKII, cdc2, v-Src, Lyn, c-Fgr, 和Syk ， IC50分别为 15 nM, 18 nM, 3 nM, 5 nM, 21 nM, 20 nM, 9 nM, 6 nM, 20 nM, 2 nM, 和 16 nM。^[3] Staurosporine (1 μM) 诱导 PC12细胞90%以上凋亡,这种作用可被过量表达的Bcl-2抑制,或者zVAD-fmk, cycloheximide (10 μM) 及actinomycin D (5 μM)处理也可抑制。相应地, Staurosporine处理，诱导细胞内游离钙水平 [Ca²⁺]_i快速且持久的提升，线粒体活性氧（ROS）的积累,及随后的线粒体功能障碍。^[4]通过caspase-8激活和Bid 分裂，功能性caspase-3的表达可增强Staurosporine诱导MCF7细胞死亡。^[5] 1 μM Staurosporine处理，只部分抑制IL-3刺激的Bcl2 磷酸化，而完全阻断PKC调节的 Bcl2磷酸化。^[6] Staurosporine 诱导人类包皮成纤维细胞AG-1518凋亡,根据溶酶体组织蛋白酶D调节的细胞色素 c释放和 caspase 激活。^[7] 除了激活传统线粒体凋亡通路, Staurosporine触发一种新型内在凋亡通路, 依赖Apaf-1存在时对caspase-9的激活。^[8]

Cell Data

Cell Lines	Assay Type	Concentration	Incubation Time	Activity Description	PMID
human colon carcinoma cell line HCT116	MmrQSpVv[3Srb36gZZN{[Xl?			M4HZO2NwdmOnboTyZZRqd25icnXxeYlz\WRiZn;yJIdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJINwdG:wIHPhdoNqdm:vYTDj[YxtKGyrbnWgTGNVOTF4LDDJR\|UxRTZibl2u	NXr4dHZbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW1N\|c{PDVpPkG1OVM4OzR3PD;hQi=>
human PBMC	NGDCeo5HfW6ldHnvckBie3OjeR?=		NUHNe3ExOjRiaB?=	NH7mc4lUfXCycnXzd4lwdiCxZjDJUFIheHKxZIXjeIlwdiCrbjDoeY1idiCSQl3DJIFnfGW{IEK0JIhzeyCkeTDFUGlUSSxiSVO1NF0yPiCwTT6=	MlP6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh3OEWwOFYoRjF6NUi1NFQ3RC:jPh?=
endothelial cells	NGm0RXpHfW6ldHnvckBie3OjeR?=			NEjtN\|NG\m[nY4TpeoUh\G:\|ZTDh[4FqdnO2IIDsZZNucW6xZ3XuJIFkfGm4YYTvdkBi[3Srdnn0fUB{fGmvdXzheIVlKGK7IIDoc5Jjd2xiZYP0[ZIhcW5iZX7kc5Rp\WyrYXygZ4VtdHNuIFXEOVAhRSB5LkWg{txONg>?	NITr[W49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi96N{C5NFk2Lz56N{C5NFk2RC:jPh?=
Sf9 insect cells	MnHSSpVv[3Srb36gZZN{[Xl?			M{DWNWlvcGmkaYTpc44hd2ZicILveIVqdiCtaX7hd4UhSyhzOkHtbZh1fXKnIH;mJHBMSyCjbIDoZUAnKGKndHGpJIV5eHKnc4Pl[EBqdiCVZkmgbY5{\WO2IHPlcIx{NCCLQ{WwJF0hOC5yMjFOwG0v	MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek86QDd\|NkC1K\|46QDd\|NkC1QE9iRg>?
LoVo cells	NXTHfWlrSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=			NFrXdYFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIHPvcI9vKGOjbnPldkBk\WyuIHzpcoUhMEyxVn:gZ4VtdHNrIIXzbY5oKE2WVDDhd5NigSxiSVO1NEA:KDBwMECxJO69VS5?	MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOTV7MUWwOUc,OTF3OUG1NFU9N2F-
umbilical vein endothelial cells	NWfpO4JsSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=			NX\BW29ESW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjD1cYJqdGmlYXygeoVqdiCnbnTveIhmdGmjbDDj[YxteyBqSGXWSWN{MSC3c3nu[{BOXFRiYYPzZZktKEmFNUCgQUAxNjByNDFOwG0v	NGTh[GE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUW5NVUxPSd-MUG1PVE2ODV:L3G+
ST-486 cells	MV;BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?			MYfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHL1dotqfCCueX3wbI9u[SClZXzsJIxqdmViKGPUMVQ5PiClZXzsd{khfXOrbnegUXRVKGG\|c3H5MEBKSzVyIE2gNE4xODdizszNMi=>	NWXFdGo6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUG1PVE2ODVpPkGxOVkyPTB3PD;hQi=>
DLD-1 cells	Mli0RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?			MlvtRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiClb3zvckBk[W6lZYKgZ4VtdCCuaX7lJEhFVERvMTDj[YxteylidYPpcochVVSWIHHzd4F6NCCLQ{WwJF0hOC5yMEmg{txONg>?	NIj4W5A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUW5NVUxPSd-MUG1PVE2ODV:L3G+
HEK293 cells	MX3GeY5kfGmxbjDhd5NigQ>?			MlXxTY5pcWKrdHnvckBw\iCSS1OtZoV1[SCLSTDt[YRq[XSnZDDJUE05KHKnbHXhd4Uh\nKxbTDISWszQTNiY3XscJMh[nliRVzJV2EtKEmFNUCgQUAxNjB5NzFOwG0v	NXjsSHEyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUK5OFE{OzFpPkGyPVQyOzNzPD;hQi=>
P19 cells	M3rON2Z2dmO2aX;uJIF{e2G7			NYLLWmNNUW6qaXLpeIlwdiCxZjDQcIF1\WyndD3k[ZJqfmWmIHfyc5d1cCCoYXP0c5IhemWlZYD0c5IhcW5iUEG5JINmdGy\|LDDJR\|UxKD1iMD6wNFIh\|ryPLh?=	M4DFVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{exOFE6Lz5zNUe3NVQyQTxxYU6=
P19 cells	MVzGeY5kfGmxbjDhd5NigQ>?			MUDJcohq[mm2aX;uJI9nKFCuYYTlcIV1NWSncnn2[YQh\3Kxd4ToJIZi[3SxcjDy[YNmeHSxcjDpckBROTliY3XscJMtKEmFNUCgQUAxNjByMjFOwG0v	NGCwTlM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUe3NVQyQSd-MUW3O\|E1OTl:L3G+
P19 cells	Ml\OSpVv[3Srb36gZZN{[Xl?			MkXDTY5pcWKrdHnvckBw\iCScn;0[YlvKEurbnHz[UBCKGmwIGCxPUBk\WyuczygTWM2OCB;IECuNFA1KM7:TT6=	Mn3NQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV5N{G0NVkoRjF3N{exOFE6RC:jPh?=
P19 cells	M2jS[mZ2dmO2aX;uJIF{e2G7			NHHDc4xKdmirYnn0bY9vKG:oIFPhcINqfW1xY3HscY9lfWyrbj3k[ZBmdmSnboSgdJJwfGWrbjDrbY5ie2VidInw[UBKUSCrbjDQNVkh[2WubIOsJGlEPTBiPTCwMlAxPiEQvF2u	NWPjO4lQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3O\|E1OTlpPkG1O\|cyPDF7PD;hQi=>
P19 cells	NFS1cZBHfW6ldHnvckBie3OjeR?=			NH\uUXRKdmirYnn0bY9vKG:oIFP5Z4xqdi2mZYDlcoRmdnRia3nuZZNmKDFiaX6gVFE6KGOnbHzzMEBKSzVyIE2gNE4xODhizszNMi=>	M4PrXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{exOFE6Lz5zNUe3NVQyQTxxYU6=
P19 cells	NYfxeopRTnWwY4Tpc44h[XO\|YYm=			NGfWV4pKdmirYnn0bY9vKG:oIG\hd4N2dGG{IHXu[I91cGWuaXHsJIdzd3e2aDDmZYN1d3JicnXj[ZB1d3JiaX6gVFE6KGOnbHzzMEBKSzVyIE2gNE4xOTRizszNMi=>	NIjob4M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUe3NVQyQSd-MUW3O\|E1OTl:L3G+
HEK293 cells	MnrUSpVv[3Srb36gZZN{[Xl?			M3vscWlvcGmkaYTpc44hd2ZiSVytPEBz\WynYYPlJIJ6KEiHS{K5N{Bk\WyuczDlfJBz\XO\|aX7nJHBMSy2kZYThNkwhUUN3MDC9JFAvODd5IN88UU4>	MoeyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV5N{G0NVkoRjF3N{exOFE6RC:jPh?=
P19 cells	NG\sOpBHfW6ldHnvckBie3OjeR?=			NH7yXWVKdmirYnn0bY9vKG:oIFnud5VtcW5icnXj[ZB1d3Jia3nuZZNmKGmwIGCxPUBk\WyuczygTWM2OCB;IECuNkDPxE1w	NIfkW2M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUe3NVQyQSd-MUW3O\|E1OTl:L3G+
P19 cells	NYe3codQTnWwY4Tpc44h[XO\|YYm=			MX;Jcohq[mm2aX;uJI9nKEOjc3XpckBscW6jc3WgNUBqdiCSMUmgZ4VtdHNuIFnDOVAhRSBzLkSg{txONg>?	MmrjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV5N{G0NVkoRjF3N{exOFE6RC:jPh?=
FL5.12-Akt1 cells	M3r0OWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7			MnP0RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDGUFUvOTJvQXv0NUBk\WyuczDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjJ7IN88UU4>	NF;0[Yk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkSwN\|YzPid-MU[0NFM3OjZ:L3G+
MiaPaCa-2 cells	MmrpRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?			NY\vS2RjSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBOcWGSYVPhMVIh[2WubIOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC5\|NzFOwG0v	MkLHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ2MEO2NlYoRjF4NECzOlI3RC:jPh?=
FL5.12-Akt1 cells	NU\4fId1TnWwY4Tpc44h[XO\|YYm=			MW\BZ5Rqfmm2eTDh[4FqdnO2IFfTT\|MhcW5iRly1MlEzNUGtdEGgZ4VtdHNuIFXDOVAhRSByLkS2JO69VS5?	M{PWVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NECzOlI3Lz5zNkSwN\|YzPjxxYU6=
MiaPaCa-2 cells	MWTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?			M2nEZWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTXnhVIFE[S1{IHPlcIx{NCCLQ{WwJF0hOC5\|NzFOwG0v	MnrNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ2MUO3PFAoRjF4NEGzO\|gxRC:jPh?=
FL5.12-Akt1 cells	M3HKXmZ2dmO2aX;uJIF{e2G7			NUfPOVJqSWO2aY\peJkh[WejaX7zeEBIW0t\|IIDoc5NxcG:{eXzheIlwdiCrbjDGUFUvOTJvQXv0NUBk\WyuczygSWM2OCB;IECuOFYh\|ryPLh?=	NYTycYV4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[0NVM4QDBpPkG2OFE{PzhyPD;hQi=>
Sf21 cells	MnPlSpVv[3Srb36gZZN{[Xl?			MYDJcohq[mm2aX;uJI9nKEqDS{Og[ZhxemW\|c3XkJIlvKFOoMkGgZ4VtdHNuIFnDOVAhRSByLkCwOkDPxE1w	MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzB6OEC1PUc,OTdyOEiwOVk9N2F-
U937 cells	NXTLR2tDS3m2b4TvfIlkcXS7IHHzd4F6			NG[5[YZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBWQTN5IHPlcIx{NCCLQ{WwJF0hOiEQvF2u	M4LTfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MEi4NFY4Lz5zN{C4PFA3PzxxYU6=
Sf9 cells	M4jYbGZ2dmO2aX;uJIF{e2G7		NUfaV2xEOSCvaX6=	NVfNS2xqUW6qaXLpeIlwdiCxZjDoeY1idiCIeX6g[ZhxemW\|c3XkJIlvKFOoOTDj[YxteyCjZoTldkAyKG2rbjDifUBGVEmVQTDpckBxemW\|ZX7j[UBw\iBzIIXtc4wwVCCDVGCsJGlEPTBiPTCwMlAxPSEQvF2u	NEHsdIs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{OxOVg2Oyd-MUezNVU5PTN:L3G+
Sf9 cells	Mo[0SpVv[3Srb36gZZN{[Xl?		NYnqTYdpOjBibXnudy=>	NYP0XmY3UW6qaXLpeIlwdiCxZjDoeY1idiCIeX6g[ZhxemW\|c3XkJIlvKFOoOTDj[YxteyCjZoTldkAzOCCvaX7zJIJ6KEWOSWPBJIlvKHC{ZYPlcoNmKG:oIEGgeY1wdC:OIFHUVEwhUUN3MDC9JFAvODF3IN88UU4>	MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzNzNUi1N{c,OTd\|MUW4OVM9N2F-
Sf9 cells	M4PHOmZ2dmO2aX;uJIF{e2G7		MnHlNUBucW5?	NGnadIdKdmirYnn0bY9vKG:oIHj1cYFvKE[7bjDlfJBz\XO\|ZXSgbY4hW2Z7IHPlcIx{KGGodHXyJFEhdWmwIHL5JGVNUVODIHnuJJBz\XOnbnPlJI9nKDFyIIXtc4wwVCCDVGCsJGlEPTBiPTCwMlA{PiEQvF2u	NGHLOWg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{OxOVg2Oyd-MUezNVU5PTN:L3G+
Sf9 cells	NWLsWW5tTnWwY4Tpc44h[XO\|YYm=		NEiyRVMzOCCvaX7z	MYDJcohq[mm2aX;uJI9nKGi3bXHuJGZ6diCneIDy[ZN{\WRiaX6gV4Y6KGOnbHzzJIFnfGW{IEKwJI1qdnNiYomgSWxKW0FiaX6gdJJme2WwY3Wgc4YhOTBidX3vcE9NKEGWUDygTWM2OCB;IECuNFg{KM7:TT6=	M4W4NlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{G1PFU{Lz5zN{OxOVg2OzxxYU6=
Sf9 cells	MUfGeY5kfGmxbjDhd5NigQ>?		NFm4elQyKG2rbh?=	NFzCbYVKdmirYnn0bY9vKG:oIHj1cYFvKE[7bjDlfJBz\XO\|ZXSgbY4hW2Z7IHPlcIx{KGGodHXyJFEhdWmwIHL5JGVNUVODIHnuJJBz\XOnbnPlJI9nKDFyMDD1cY9tN0xiQWTQMEBKSzVyIE2gNE4zPyEQvF2u	NXS4UYhIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezNVU5PTNpPkG3N\|E2QDV\|PD;hQi=>
Sf9 cells	NH\KV3dHfW6ldHnvckBie3OjeR?=		MoryNlAhdWmwcx?=	MmjKTY5pcWKrdHnvckBw\iCqdX3hckBHgW5iZYjwdoV{e2WmIHnuJHNnQSClZXzsd{Bi\nSncjCyNEBucW6\|IHL5JGVNUVODIHnuJJBz\XOnbnPlJI9nKDFyMDD1cY9tN0xiQWTQMEBKSzVyIE2gNE42OSEQvF2u	MoTkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd\|MUW4OVMoRjF5M{G1PFU{RC:jPh?=
A549 cells	MmP6R5l1d3SxeHnjbZR6KGG\|c3H5		NHX1ZZc4OiCq	MnLMR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bi\nSncjC3NkBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDt[ZRpd2RuIFfJOVAhRSByLkCwNlQh\|ryPLh?=	NXLmTm1IRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0PFQ4PzVpPkG4OFg1Pzd3PD;hQi=>
MDA-MB-231 cells	MX7DfZRwfG:6aXPpeJkh[XO\|YYm=		MoqwO\|IhcA>?	MXTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvMkOxJINmdGy\|IHHmeIVzKDd{IHjyd{BjgSC\|dXzmc5Jpd2SjbXnu[UBDKG2ndHjv[EwhT0l3MDC9JFAvODB5MTFOwG0v	NYjjRW5PRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0PFQ4PzVpPkG4OFg1Pzd3PD;hQi=>
HT29 cells	NGTFN3FEgXSxdH;4bYNqfHliYYPzZZk>		NIjwTIg4OiCq	NFSyTmdEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXDJ7IHPlcIx{KGGodHXyJFczKGi{czDifUB{fWyob4Loc4RidWmwZTDCJI1mfGixZDygS2k2OCB;IECuNFExQSEQvF2u	NEjzXGo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOES4OFc4PSd-MUi0PFQ4PzV:L3G+
MCF7 cells	MYLGeY5kfGmxbjDhd5NigQ>?			MmDuTY5pcWKrdHnvckBw\iCSS1GgbY4hcHWvYX6gUWNHPyClZXzsd{BjgSCjcoLhfU1j[XOnZDDmcJVwemW\|Y3XuZ4Uh[XO\|YYmsJGtqKD1iMD6wNFUh\|ryPLh?=	Mof4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4NU[zOlkoRjF6NkW2N\|Y6RC:jPh?=
MCF7 cells	Ml\xSpVv[3Srb36gZZN{[Xl?			NGjJZmVKdmirYnn0bY9vKG:oIGDLRUBqdiCqdX3hckBOS0Z5IHPlcIx{KGK7IHHydoF6NWKjc3XkJIZtfW:{ZYPj[Y5k\SCjc4PhfUwhUUN3MDC9JFIh\|ryPLh?=	MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZ3NkO2PUc,OTh4NU[zOlk9N2F-
Sf9 cells	M3vPcWZ2dmO2aX;uJIF{e2G7			NWrHOGN6UW6qaXLpeIlwdiCxZjDoeY1idiCVeXug[ZhxemW\|c3XkJIlvKFOoOTDj[YxteyxiSVO1NEA:KDBwMECzJO69VS5?	MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDh{M{e4OEc,OTh6MkO3PFQ9N2F-
Sf9 cells	MmPmSpVv[3Srb36gZZN{[Xl?			NHWzUXpKdmirYnn0bY9vKG:oIHj1cYFvKFqDUEewJIV5eHKnc4Pl[EBqdiCVZkmgZ4VtdHNuIFnDOVAhRSByLkC1N{DPxE1w	MoDKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh6MkO3PFQoRjF6OEKzO\|g1RC:jPh?=
insect cells	NUPhO\|VGTnWwY4Tpc44h[XO\|YYm=			NGDqV2xKdmirYnn0bY9vKG:oIHj1cYFvKHKnY3;tZolv[W62IGDpcVEh\XiycnXzd4VlKGmwIHnud4VkfCClZXzsd{BjgSCKVGLGMEBKSzVyIE2gNE4xOSEQvF2u	MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTF5OUC3Okc,OTlzN{mwO\|Y9N2F-
HT-29 cells	NEnrdWJCeG:ydH;zbZMh[XO\|YYm=		MkTpNkBp	MWXJcoR2[3Srb36gc4Yh[XCxcITvd4l{KGmwIHj1cYFvKEiWLUK5JINmdGy\|IHHzd4V{e2WmIHHzJINp[W6pZTDpckBucXSxY3jvcoRzcWGuIITyZY5{dWWvYoLhcoUheG:2ZX70bYFtKGGodHXyJFIhcHK\|IHL5JGpEOSC\|dHHpcolv\yCkYYPl[EBndHWxcnXzZ4Vv[2ViYYPzZZktKEWGNUCgQUAxNjByMk[g{txONg>?	MmXpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl2MkKyNFYoRjF7NEKyNlA3RC:jPh?=
insect Sf21 cells	NGjtSpBHfW6ldHnvckBie3OjeR?=			MXjJcohq[mm2aX;uJI9nKEqDS{Og[ZhxemW\|c3XkJIlvKGmwc3XjeEBU\jJzIHPlcIx{KGG\|c3Xzd4VlKGG\|IHnubIljcXSrb36gc4Yh[mmxdHnufYxifGWmIIP1ZpN1emG2ZTDwbI9{eGixconsZZRqd25uIFnDOVAhRSByLkCwOkDPxE1w	NFzU[pY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUSyO\|IxOyd-MUm0NlczODN:L3G+
Jurkat cells	Mo\KRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?			NHqwTGRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JGpCUzNiZYjwdoV{e2mwZzDJUFIue3SrbYXsZZRm\CCqdX3hckBLfXKtYYSgZ4VtdHNuIFnDOVAhRSByLkC3NUDPxE1w	NXHSeo54RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm0NlczODNpPkG5OFI4OjB\|PD;hQi=>
Jurkat cells	M3faUGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7			NFjTfZBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JGpCUzNiZYjwdoV{e2mwZzDoeY1idiC{ZYP0bY5oKEq3cnvheEBk\WyuczygTWM2OCB;IECuN\|EyKM7:TT6=	MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTR{N{KwN{c,OTl2MkeyNFM9N2F-
HUE cells	MUjGeY5kfGmxbjDhd5NigQ>?		NFHCWGs6OCCvaX7z	NV3FfpB1UW6qaXLpeIlwdiCxZjDWSWdHWjJiaX6gTHVGKGOnbHzzJIF{e2W\|c3XkJIF{KGmwaHnibZRqd25ib3[gWmVITi2rbnT1Z4VlKGG3dH;wbI9{eGixconsZZRqd25idILlZZRm\CCob4KgPVAhdWmwczDi[YZwemViVlXHSkBkcGGubHXu[4Uh[nliRVzJV2EtKEmFNUCgQUAxNjB5IN88UU4>	MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODF5MEG2N{c,OjBzN{CxOlM9N2F-
Sf9 cells	M1rSdGZ2dmO2aX;uJIF{e2G7		M1XaRlYxKG2rboO=	NWXGeZZlUW6qaXLpeIlwdiCxZjDoeY1idiC{ZXPvcYJqdmGwdDDHV3Qu\nW\|ZXSgUmlMKGW6cILld5Nm\CCrbjDT[lkh[2WubIOgZYZ1\XJiNkCgcYlveyCkeTDyZYRqd22ndILpZ{Bxem:2ZXnuJItqdmG\|ZTDhd5NigSxiSVO1NEA:KDJwMzFOwG0v	Mkn6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB3OEC1OVIoRjJyNUiwOVUzRC:jPh?=
Sf21 cells	MYDGeY5kfGmxbjDhd5NigQ>?	NYjKNVZZOzBidV2=		MkTyTY5pcWKrdHnvckBw\iCqdX3hckBEUEt{IHvpcoF{\SCneIDy[ZN{\WRiaX6gbY5{\WO2IGPmNlEh[2WubIOgeZNqdmdicHjvd5Bpdy2FUlXCeIll\SCjczDzeYJ{fHKjdHWgZZQhOzBidV2sJGlEPTBiPTCwMlAzPyEQvF2u	MnvOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF\|M{S3PVYoRjJzM{O0O\|k3RC:jPh?=
Sf21 cells	MnmxSpVv[3Srb36gZZN{[Xl?	NELSbmc{OCC3TR?=		MYXJcohq[mm2aX;uJI9nKGi3bXHuJJJm[2:vYnnuZY51KEmNSz3hcJBp[SCneIDy[ZN{\WRiaX6gbY5{\WO2IGPmNlEh[2WubIOgeZNqdmdicHjvd5Bpdy2XbHnnbJQuUWujcIDhRk1idHCqYTDhd{B{fWK\|dILheIUh[XRiM{CgeW0tKEmFNUCgQUAxNjB\|OTFOwG0v	NVHob4M{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGzN\|Q4QTZpPkKxN\|M1Pzl4PD;hQi=>
Sf21 cells	MV7GeY5kfGmxbjDhd5NigQ>?	Mon5N\|AhfU1?		NGrOZVJKdmirYnn0bY9vKG:oIHj1cYFvKHKnY3;tZolv[W62IFnLT{1j\XSjIHX4dJJme3OnZDDpckBqdnOnY4SgV4YzOSClZXzsd{B2e2mwZzDwbI9{eGixLWXsbYdpfC2La3HwdIFDNWGucHjhJIF{KHO3YoP0doF1\SCjdDCzNEB2VSxiSVO1NEA:KDBwNEmg{txONg>?	MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN\|NEe5Okc,OjF\|M{S3PVY9N2F-
HeLa cells	MVfDfZRwfG:6aXPpeJkh[XO\|YYm=		NH7NWpU1QCCq	NIDtXm9EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjByMECwOEDPxE1w	MlfPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF\|OEixPVEoRjJzM{i4NVkyRC:jPh?=
MCF7 cells	NYXNeWxIS3m2b4TvfIlkcXS7IHHzd4F6		Mm\ZOFghcA>?	M1\2b2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvODVizszNMi=>	NWLZVZlHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGzPFgyQTFpPkKxN\|g5OTlzPD;hQi=>
HT-29 cells	NV;VU3B2TnWwY4Tpc44h[XO\|YYm=		NFrJS5czKGh?	MYXF[oZm[3Rib36gcYl1d2Oqb37kdolidCCvZX3idoFv\SCyb4TlcpRq[WxiaX6gbJVu[W5iSGStNlkh[2WubIOgZYZ1\XJiMjDodpMhfXOrbnegTmMuOSC\|dHHpcolv\yCkeTDmcJVwemW\|Y3XuZ4Uh[XO\|YYmsJGlEPTBiPTCwMlAxOiEQvF2u	MkWxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF2MkizO\|UoRjJzNEK4N\|c2RC:jPh?=
HeLa cells	NHnaU3dEgXSxdH;4bYNqfHliYYPzZZk>		NIfucWM1QCCq	NVTOdWl3S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC5yMECwNFQh\|ryPLh?=	MnHYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF2OEi2OVUoRjJzNEi4OlU2RC:jPh?=
MCF7 cells	MYfDfZRwfG:6aXPpeJkh[XO\|YYm=		NFnKN241QCCq	Ml;xR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG\|c3H5MEBKSzVyIE2gNE4xPSEQvF2u	MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTR6OE[1OUc,OjF2OEi2OVU9N2F-
HT-29 cells	MWrGeY5kfGmxbjDhd5NigQ>?			NXjiU25HUW6qaXLpeIlwdiCxZjDtbZRw[2ixbnTybYFtKG2nbXLyZY5mKHCxdHXueIlidCCrbjDoeY1idiCKVD2yPUBk\WyuczD1d4lv\yCMQ{Gg[JlmKHO2YXnubY5oKGK7IH\seY9z\XOlZX7j[UBxdGG2ZTDy[YFl\XJiYYPzZZktKEmFNUCgQUAxNjByMkWg{txONg>?	Ml7TQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF3MUOyPVMoRjJzNUGzNlk{RC:jPh?=
SF268 cells	MY\DfZRwfG:6aXPpeJkh[XO\|YYm=		MYm0PEBp	MlTLR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gV2YzPjhiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFAvODR2IN88UU4>	MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTVzM{K5OEc,OjF3MUOyPVQ9N2F-
CHOK1 cells	M1npemN6fG:2b4jpZ4l1gSCjc4PhfS=>		MUS0PEBp	NHPoOWhEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBEUE:NMTDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCJSUWwJF0hOC5zMzFOwG0v	MnfhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF3MUOyPVQoRjJzNUGzNlk1RC:jPh?=
H460 cells	MXrDfZRwfG:6aXPpeJkh[XO\|YYm=		MXO0PEBp	M4LzbGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGg1PjBiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFMvPiEQvF2u	NEDMeoc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUWxN\|I6PCd-MkG1NVMzQTR:L3G+
HT-29 cells	NX61UFdwS3m2b4TvfIlkcXS7IHHzd4F6		NX7rTHlGPDhiaB?=	NInF[2ZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXC1{OTDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCJSUWwJF0hOy54IN88UU4>	MkPGQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF3MUOyPVQoRjJzNUGzNlk1RC:jPh?=
MCF7 cells	NWfVV4RYS3m2b4TvfIlkcXS7IHHzd4F6		M2DJPVQ5KGh?	NIKyb4VEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKEeLNUCgQUAyOSEQvF2u	MkfXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF3MUOyPVQoRjJzNUGzNlk1RC:jPh?=
SW1116 cells	M2XqemZ2dmO2aX;uJIF{e2G7		NFfoWZczPCCq	MWjJcohq[mm2aX;uJI9nKHSnbH;t[ZJie2ViaX6gbJVu[W5iU2exNVE3KGOnbHzzJIFnfGW{IEK0JIhzeyCkeTDUVmFRNVCFUj3FUGlUSSCjc4PhfUwhUUN3MDC9JFgvOzJizszNMi=>	NV;hWW9jRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG5OlI2OjNpPkKxPVYzPTJ\|PD;hQi=>
HT-29 cells	M3\OXWFxd3C2b4Ppd{Bie3OjeR?=		M1TWVlIhcA>?	MULJcoR2[3Srb36gc4Yh[XCxcITvd4l{KGmwIHj1cYFvKEiWLUK5JINmdGy\|IHHzd4V{e2WmIILl[JVkfGmxbjDv[kBucXSxY3jvcoRzcWGuIH3lcYJz[W6nIIDveIVvfGmjbDDh[pRmeiB{IHjyd{BjgSC3c3nu[{BLSzFic4ThbY5qdmdiYomg[ox2d3Knc3PlcoNmKGOnbHytZoF{\WRiYYPzZZktKEWGNUCgQUAxNjByMk[g{txONg>?	NIfEW\|Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUm3N\|ExOSd-MkG5O\|MyODF:L3G+
LoVo cells	MVPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		NXz5XZF{PDhidH:gO\|IhcA>?	MXTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEyxVn:gZ4VtdHNiYX\0[ZIhPDhidH:gO\|IhcHK\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvODBzIN88UU4>	MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjF6MkmyPUc,OjJzOEK5Nlk9N2F-
ST486 cells	MWHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		MX20PEB1dyB5MjDo	NWXYd2p5SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTWFQ5PiClZXzsd{Bi\nSncjC0PEB1dyB5MjDodpMh[nliTWTUJIF{e2G7LDDJR\|UxKD1iMD6wNFch\|ryPLh?=	NHTWRmM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkG4NlkzQSd-MkKxPFI6Ojl:L3G+
DLD1 cells	NIfMbVZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		MlXCOFghfG9iN{KgbC=>	NGjnOGhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFTMSFEh[2WubIOgZYZ1\XJiNEigeI8hPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwMEC5JO69VS5?	MmDpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzOEK5NlkoRjJ{MUiyPVI6RC:jPh?=
B16F10 cells	NFfNblFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		Mo[wOFghcA>?	MVTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IH3veZNmKEJzNl[xNEBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR\|UxKD1iMj64NkDPxE1w	NGnvUpk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkWwN\|M3PCd-MkK1NFM{PjR:L3G+
MCF7 cells	Mli5RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?		NYfYeIo1PDhiaB?=	M4DhUmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVPGO{Bk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR\|UxKD1iMz6wO{DPxE1w	NVnOU5dZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK1NFM{PjRpPkKyOVA{OzZ2PD;hQi=>
A431 cells	Mlz3R5l1d3SxeHnjbZR6KGG\|c3H5		MlLnNlQhcA>?	M1fPXWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE1OzFiY3XscJMh[W[2ZYKgNlQhcHK\|IIXzbY5oKEGwbnX4bY4hXmWISWTDM5Bzd3CrZHn1cUBqd2SrZHWgd5RicW6rbnegZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC5yNzFOwG0v	MlviQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3NEGwOVEoRjJ{NUSxNFUyRC:jPh?=
MCF7 cells	NIjSZVNEgXSxdH;4bYNqfHliYYPzZZk>		NGPsVW8zPCCq	NXvlUVNCS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkAzPCCqcoOgeZNqdmdiQX7u[ZhqdiCYZV\JWGMweHKxcHnkbZVuKGmxZHnk[UB{fGGrbnnu[{BjgSCPVGSgZZN{[XluIFnDOVAhRSByLkG4JO69VS5?	MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjV2MUC1NUc,OjJ3NEGwOVE9N2F-
BJ cells	NXPVSmt1S3m2b4TvfIlkcXS7IHHzd4F6		MkXJO\|IhcA>?	NU\uXmlYS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSkpiY3XscJMh[W[2ZYKgO\|IhcHK\|IHL5JGNidGOnaX6gRW0h[XO\|YYmsJGlEPTBiPTCwMlAxOiEQvF2u	NU\v[phCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5NlExQDFpPkKyPVIyODhzPD;hQi=>
CEM cells	NVO0N4tCS3m2b4TvfIlkcXS7IHHzd4F6		MlywO\|IhcA>?	NVHPO5lTS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hS0WPIHPlcIx{KGGodHXyJFczKGi{czDifUBE[WylZXnuJGFOKGG\|c3H5MEBKSzVyIE2gNE4xOjNizszNMi=>	MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjl{MUC4NUc,OjJ7MkGwPFE9N2F-
MCF7 cells	M4Ky[GN6fG:2b4jpZ4l1gSCjc4PhfS=>		M{T1[FczKGh?	NGLUR5dEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFczKGi{czDifUBE[WylZXnuJGFOKGG\|c3H5MEBKSzVyIE2gNE4xPjRizszNMi=>	NV;hT5JXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5NlExQDFpPkKyPVIyODhzPD;hQi=>
HeLa cells	NVHVSZhnS3m2b4TvfIlkcXS7IHHzd4F6		MV[3NkBp	M3fDWWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgO\|IhcHK\|IHL5JGNidGOnaX6gRW0h[XO\|YYmsJGlEPTBiPTCwMlE4PSEQvF2u	MkjmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ7MkGwPFEoRjJ{OUKxNFgyRC:jPh?=
HepG2 cells	M3X5VWZ2dmO2aX;uJIF{e2G7		NYrFU3IxOjRiaB?=	NFWzVHJKdmirYnn0bY9vKG:oIITlcI9u\XKjc3WgbY4hcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgNlQhcHK\|IHL5JHRTSVBvUFPSMWVNUVODIHHzd4F6NCCLQ{WwJF0hPC5zNDFOwG0v	MlvsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNyMUiwPVYoRjJ\|MEG4NFk3RC:jPh?=
SW1116 cells	MlfmRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?		MWG0PEBp	M3;wc2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU2exNVE3KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQhdWW2aH;kMEBKSzVyIE2gOE46PSEQvF2u	NWjkN5R2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwNVgxQTZpPkKzNFE5ODl4PD;hQi=>
HepG2 cells	MYjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		NYfDcGN2PDhiaB?=	MnTYRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiCKZYDHNkBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJI1mfGixZDygTWM2OCB;IE[uO\|Mh\|ryPLh?=	M2K5fFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ\|MEG4NFk3Lz5{M{CxPFA6PjxxYU6=
BGC823 cells	MoW4RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?		MYC0PEBp	NXL6VG9ISW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDCS2M5OjNiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JG1VXCCvZYToc4QtKEmFNUCgQUA3Njh\|IN88UU4>	M2nEUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ\|MEG4NFk3Lz5{M{CxPFA6PjxxYU6=
HeLa cells	MknuRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?		MVi0PEBp	MYTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEinTHGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDt[ZRpd2RuIFnDOVAhRSB7LkGyJO69VS5?	NHfITmM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{CxPFA6Pid-MkOwNVgxQTZ:L3G+
HCT116 cells	M3r2cWZ2dmO2aX;uJIF{e2G7			MlG1TY5pcWKrdHnvckBw\iCWTlnLMY1m\GmjdHXkJHRETjRxYnX0ZU1k[XOnaX6geJJidnOlcnnweIlwdiCrbjDoeY1idiCKQ2SxNVYh[2WubIOgZpkh[mW2YT3sZYN1[W2jc3WgdoVxd3K2ZYKg[4Vv\SCjc4PhfUwhUUN3MDC9JFAvODN7IN88UU4>	NXLHellvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyN\|IxPjBpPkKzNlMzODZyPD;hQi=>
HepG2 cells	MVHGeY5kfGmxbjDhd5NigQ>?		NVXlUmJxPDhiaB?=	NXjyPGtsUW6qaXLpeIlwdiCxZjD0[YxwdWW{YYPlJIlvKGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBVWkGSLWDDVk1GVEmVQTygTWM2OCB;IEiuN{DPxE1w	NX7QPY5zRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyO\|k5PjRpPkKzNlc6QDZ2PD;hQi=>
SW1116 cells	MmP1SpVv[3Srb36gZZN{[Xl?		NYnZbpJnOjRiaB?=	M3L0XGlvcGmkaYTpc44hd2ZidHXsc41memG\|ZTDpckBpfW2jbjDTW\|EyOTZiY3XscJMh[W[2ZYKgNlQhcHK\|IHL5JHRTSVBvUFPSMWVNUVODIHHzd4F6NCCLQ{WwJF0hPC5zODFOwG0v	MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDJ6Nke2NUc,OjR{OE[3OlE9N2F-
KE-97 cells	MoX5R5l1d3SxeHnjbZR6KGG\|c3H5		M1TD[\|czKGh?	NWe2enFMS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hU0VvOUegZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KEOnbHzUbZRz\S2JbH:gcJVucW6nc3PlcpQh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVAhRSByLkGzJO69VS5?	MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDN{OEK4N{c,OjR\|MkiyPFM9N2F-
Jurkat cells	NIPWVJFEgXSxdH;4bYNqfHliYYPzZZk>		MlW2O\|IhcA>?	Mmr4R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTpVzc2G2IHPlcIx{KGGodHXyJFczKGi{czDifUBE\WyuVHn0doUuT2yxIHz1cYlv\XOlZX70JINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwJF0hOC5zNDFOwG0v	MnjtQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR\|MkiyPFMoRjJ2M{K4Nlg{RC:jPh?=
HuH7 cells	NEPZNpZEgXSxdH;4bYNqfHliYYPzZZk>		MoL0O\|IhcA>?	M3PGZWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGh2UDdiY3XscJMh[W[2ZYKgO\|IhcHK\|IHL5JGNmdGyWaYTy[U1IdG9ibIXtbY5me2OnboSgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUCgQUAxNjJ\|IN88UU4>	M4LkNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{K4Nlg{Lz5{NEOyPFI5OzxxYU6=
BGC823 cells	NWjnRXcxS3m2b4TvfIlkcXS7IHHzd4F6		NXq5NoNQPzJiaB?=	NGjZW\|FEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBDT0N6MkOgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KEOnbHzUbZRz\S2JbH:gcJVucW6nc3PlcpQh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVAhRSByLkO4JO69VS5?	NVm0UnpCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSzNlgzQDNpPkK0N\|I5Ojh\|PD;hQi=>
MCF7 cells	M4nEXGN6fG:2b4jpZ4l1gSCjc4PhfS=>		Mn3kO\|IhcA>?	MWjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDD[YxtXGm2cnWtS4xwKGy3bXnu[ZNk\W62IHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyIE2gNE42OiEQvF2u	M4[x[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{K4Nlg{Lz5{NEOyPFI5OzxxYU6=
NIH/3T3 cells	MWPDfZRwfG:6aXPpeJkh[XO\|YYm=		NIT4UIg6PiCq	MXXDfZRwfG:6aXPpeJkh[WejaX7zeEBud3W\|ZTDOTWgwO1R\|IHPlcIx{KGGodHXyJFk3KGi{czDifUBUWkJiYYPzZZktKEmFNUCgQUAxNjJizszNMi=>	M4jmUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{[xOVIyLz5{NEO2NVUzOTxxYU6=
A2780 cells	M1K3VmN6fG:2b4jpZ4l1gSCjc4PhfS=>		MVO5OkBp	MVLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBNlc5OCClZXzsd{Bi\nSncjC5OkBpenNiYomgV3JDKGG\|c3H5MEBKSzVyIE2gNE4zKM7:TT6=	MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDN4MUWyNUc,OjR\|NkG1NlE9N2F-
HT-29 cells	MWfDfZRwfG:6aXPpeJkh[XO\|YYm=		MXG5OkBp	NYLFd5ZYS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUFRvMkmgZ4VtdHNiYX\0[ZIhQTZiaILzJIJ6KFOUQjDhd5NigSxiSVO1NEA:KDBwMjFOwG0v	NHz2TJc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEO2NVUzOSd-MkSzOlE2OjF:L3G+
8505C cells	NFWwcnVEgXSxdH;4bYNqfHliYYPzZZk>		NYjaOYY4QTZiaB?=	MVvDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjC4OVA2SyClZXzsd{Bi\nSncjC5OkBpenNiYomgV3JDKGG\|c3H5MEBKSzVyIE2gNE4zKM7:TT6=	MnjoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR\|NkG1NlEoRjJ2M{[xOVIyRC:jPh?=
518A2 cells	NEPQc5pEgXSxdH;4bYNqfHliYYPzZZk>		NFOzW\|Y6PiCq	NXfhNlBQS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hPTF6QUKgZ4VtdHNiYX\0[ZIhQTZiaILzJIJ6KFOUQjDhd5NigSxiSVO1NEA:KDBwMjFOwG0v	MlTIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR\|NkG1NlEoRjJ2M{[xOVIyRC:jPh?=
MCF7 cells	MXPDfZRwfG:6aXPpeJkh[XO\|YYm=		NV\lU\|VLQTZiaB?=	M1ztRWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgPVYhcHK\|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFAvPCEQvF2u	NHi3SnA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEO2NVUzOSd-MkSzOlE2OjF:L3G+
A549 cells	M4HGVWN6fG:2b4jpZ4l1gSCjc4PhfS=>		MXi5OkBp	NUHTeHloS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA6PiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwJF0hOC54IN88UU4>	M3v6eFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{[xOVIyLz5{NEO2NVUzOTxxYU6=
V79 MZ cells	MkG4SpVv[3Srb36gZZN{[Xl?			Mnr2TY5pcWKrdHnvckBw\iCqdX3hckBidGSxc4Tldo9v\SC\|eX70bIF{\SCneIDy[ZN{\WRiaX6gWlc6KE2cIHPlcIx{KGG\|c3Xzd4VlKGG\|IHnubIljcXSrb36gc4Yh[Wymb4P0[ZJwdmVic4nueIhme2m\|LDDJR\|UxKD1iMD6wNVEh\|ryPLh?=	NXe5WFgzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS0NlI2OTlpPkK0OFIzPTF7PD;hQi=>
HEK293 cells	MWfDfZRwfG:6aXPpeJkh[XO\|YYm=		NYj5d\|JmPzJiaB?=	M4LnPWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KEiHS{K5N{Bk\WyuczDh[pRmeiB5MjDodpMh[nliQ3XscHRqfGW{R3zvJIF{e2G7LDDJR\|UxKD1iMD6wOVYh\|ryPLh?=	M2S0NFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2N{[zNlYzLz5{NEe2N\|I3OjxxYU6=
HeLa cells	MYLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		NGjPdZkzPCC2bzC0PEBp	MnrVRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiCKZVzhJINmdGy\|IHHmeIVzKDJ2IITvJFQ5KGi{czDifUBES0tvODDhd5NigSxiSVO1NEA:KDJwN{Kg{txONg>?	NGHSdWY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEe5NlgyOSd-MkS3PVI5OTF:L3G+
A549 cells	M1rBNWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7		NEm1eHYzPCC2bzC0PEBp	M1HJbWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQUW0PUBk\WyuczDh[pRmeiB{NDD0c{A1QCCqcoOgZpkhS0ONLUigZZN{[XluIFnDOVAhRSB\|LkC1JO69VS5?	NXTIUGptRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3PVI5OTFpPkK0O\|kzQDFzPD;hQi=>
HepG2 cells	Mnq5R5l1d3SxeHnjbZR6KGG\|c3H5			MXnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{whTUN3MDC9JFIh\|ryPLh?=	NHvHTWs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUOxOlMyPyd-MkWzNVY{OTd:L3G+
Raji cells	NXzRb5VTS3m2b4TvfIlkcXS7IHHzd4F6			MVXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDSZYpqKGOnbHzzMEBGSzVyIE2gNkDPxE1w	MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTNzNkOxO{c,OjV\|MU[zNVc9N2F-
BJ cells	MofiR5l1d3SxeHnjbZR6KGG\|c3H5			NUHJSWZHS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSkpiY3XscJMtKEWFNUCgQUAzKM7:TT6=	MkDEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV\|MU[zNVcoRjJ3M{G2N\|E4RC:jPh?=
HEK293 cells	NEL4NodEgXSxdH;4bYNqfHliYYPzZZk>			NE\zO3JEgXSxdH;4bYNqfHliYXfhbY5{fCCKRVuyPVMh[2WubIOsJGVEPTBiPTCyJO69VS5?	M1ryT\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3M{G2N\|E4Lz5{NUOxOlMyPzxxYU6=
A549 cells	MkTWR5l1d3SxeHnjbZR6KGG\|c3H5		M1;LUlQ5KGh?	M3niV2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgOFghcHK\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvODJizszNMi=>	NF\YN4k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUiyOVk{PCd-MkW4NlU6OzR:L3G+
HeLa cells	NV;xU4k1S3m2b4TvfIlkcXS7IHHzd4F6		NVfyNFJSPDhiaB?=	M4PIS2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvODJ3IN88UU4>	NEW3XJk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUiyOVk{PCd-MkW4NlU6OzR:L3G+
PC3 cells	M3j2e2N6fG:2b4jpZ4l1gSCjc4PhfS=>		M2jBZlQ5KGh?	NFj6UFdEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSzNiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvODNzIN88UU4>	MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTh{NUmzOEc,OjV6MkW5N\|Q9N2F-
MGC-803 cells	NVfDeGw4TnWwY4Tpc44h[XO\|YYm=		Mn6wNlQhcA>?	NFTZZYtKdmirYnn0bY9vKG:oIITlcI9u\XKjc3WgbY4hcHWvYX6gUWdENThyMzDj[YxteyCjZoTldkAzPCCqcoOgZpkhXFKDUD3QR3IuTUyLU1GgZZN{[XluIFnDOVAhRSB6Lkm3JO69VS5?	MmnxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ7MEC2OVYoRjJ4OUCwOlU3RC:jPh?=
Sf9 insect cells	NVvnfHUxTnWwY4Tpc44h[XO\|YYm=		NWPDVZlpOTBibXnudy=>	MnLjTY5pcWKrdHnvckBw\iCQLYTldo1qdmGuIFfTWEB1[WepZXSgdoVkd22kaX7hcpQh\nWubD3s[Y5ofGhiaIXtZY4hS0iNMTDlfJBz\XO\|ZXSgbY4h[mGldXzveolzfXNiU3[5JIlve2WldDDj[YxteyCjZoTldkAyOCCvaX7zJIJ6KGy3bXnu[ZNk\W62IFHEVE1IdG9iYYPzZZktKEmFNUCgQUAxNjByMUKg{txONg>?	MoPxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdyOEmyNVEoRjJ5MEi5NlEyRC:jPh?=
Sf21 cells	M{W0WWZ2dmO2aX;uJIF{e2G7		NITqOWQ3OCCvaX7z	M1[ydGlvcGmkaYTpc44hd2ZiaIXtZY4hemWlb33ibY5idnRiSlHLNkBmgHC{ZYPz[YQhcW5iU3[yNUBk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iVXzp[4h1NUODR1HHRWlGXESNRWnZWHZMTCCyaH;zdIhwenmuYYTpc44heHKnLXnuZ5Vj[XSnZDDi[YZwemVic4Xid5Rz[XSnIHHk[Il1cW:wIHHu[EBu\WG\|dYLl[EBi\nSncjC2NEBucW6\|IHL5JGxCVkOHIHTleIVkfGmxbjDt[ZRpd2RuIFnDOVAhRSByLkCwNkDPxE1w	M4KxWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MUO3N\|U6Lz5{N{GzO\|M2QTxxYU6=
Neuro2a cells	M2\LR2N6fG:2b4jpZ4l1gSCjc4PhfS=>		NFvVPGI4OiCq	NV7GTm85S3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhVmW3cn:yZUBk\WyuczDhd5Nme3OnZDDhd{Bk\WyuII\pZYJqdGm2eTDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR\|UxKD1iMD6wNVE{KM7:TT6=	NInSZ449[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEG1NlQzPyd-MkixOVI1Ojd:L3G+
MDA-MB-231 cells	MV\GeY5kfGmxbjDhd5NigQ>?		NH:yRmUyPiCq	MYrJcohq[mm2aX;uJI9nKHKndHnuc4Jt[XO2b33hJJBzd3SnaX6gdIhwe3Cqb4L5cIF1cW:wIHnuJIh2dWGwIF3ERU1OSi1{M{GgZ4VtdHNiYX\0[ZIhOTZiaILzJIJ6KEixZXPod5QhOzN\|NEKgd5RicW6rbnegZoF{\WRiZnz1c5Jme2OnbnPlJIF{e2G7LDDJR\|UxKD1iMD6wOlYh\|ryPLh?=	NUTvPJJ5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki0N\|E{PDJpPkK4OFMyOzR{PD;hQi=>
Sf9 insect cells	MYXGeY5kfGmxbjDhd5NigQ>?		MlTDNlAhdWmwcx?=	MoPBTY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCQLYTldo1qdmGubImgS3NVNXSjZ3fl[EBGT0[UIFy4OVhTN1R5OUDNM2M4QTeVIITybZBt\SCvdYThcpQh\XiycnXzd4VlKGmwIHLhZ5Vtd3[rcoXzJIlvKFOoOTDpcpNm[3RiY3XscJMheHKnaX7jeYJifGWmIH\vdkAzOCCvaX7zJIZwdGyxd3XkJIJ6KGGmZHn0bY9vKG:oIGuzN3BeNUGWUDDt[YF{fXKnZDDh[pRmeiB{IHjyd{BjgSCoaXz0[ZIu[mmwZHnu[{Bu\XSqb3SsJGlEPTBiPTCwMlAxODJ7IN88UU4>	M3vLVVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NEiyNVUyLz5{OES4NlE2OTxxYU6=
HEK293 cells	NVexUpZ[S3m2b4TvfIlkcXS7IHHzd4F6		NVHWeJVJPzJiaB?=	NUTvOlBmS3m2b4TvfIlkcXS7IHHnZYlve3RiSFXLNlk{KGOnbHzzJIF{e2W\|c3XkJIF{KGSnY4LlZZNmKGmwIHPlcIwhfmmjYnnsbZR6KGGodHXyJFczKGi{czDifUBE\WyuVHn0[ZIhT2yxIHz1cYlv\XOlZX70JIF{e2G7LDDDR\|UxKD1iMD6wNFM2PCEQvF2u	NYfWd2ZCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki2NlQ4ODFpPkK4OlI1PzBzPD;hQi=>
BT549 cells	NHTwNY1EgXSxdH;4bYNqfHliYYPzZZk>		NF20VmYzPCCq	NG\BZ5JEgXSxdH;4bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDCWFU1QSClZXzsd{BqdmO3YnH0[YQh\m:{IEK0JIhzeyCkeTDNWHQh[XO\|YYmsJGlEPTBiPTCwMlA5KM7:TT6=	NH;wWYM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEewOVQ{Oid-Mki3NFU1OzJ:L3G+
MDA-MB-468 cells	NGnlPYNEgXSxdH;4bYNqfHliYYPzZZk>		NV72SXpnOjRiaB?=	MkG2R5l1d3SxeHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVTBMW1DNTR4ODDj[YxteyCrbnP1ZoF1\WRiZn;yJFI1KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjF3IN88UU4>	NYPiV5h3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki3NFU1OzJpPkK4O\|A2PDN{PD;hQi=>
MDA-MB-231 cells	M4[3VmN6fG:2b4jpZ4l1gSCjc4PhfS=>		NH3OWYYzPCCq	MlHTR5l1d3SxeHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVTBMW1DNTJ\|MTDj[YxteyCrbnP1ZoF1\WRiZn;yJFI1KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjJ2IN88UU4>	NWr2SVNCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki3NFU1OzJpPkK4O\|A2PDN{PD;hQi=>
Vero cells	NYHoXHBtS3m2b4TvfIlkcXS7IHHzd4F6		NVnnXHM{OiCmYYnz	MYDDfZRwfG:6aXPpeJkh[WejaX7zeEBC\nKrY3HuJIdz\WWwIH3vcotmgSCYZYLvJINmdGy\|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiClZXzsJJZq[WKrbHn0fUBi\nSncjCyJIRigXNiYomgZ4VtdC22aYTldk1odG9ibIXtbY5me2OnboSgZZN{[XluIGTDOVAhRSByLkCwNlQh\|ryPLh?=	MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDd4M{[0OUc,Ojh5NkO2OFU9N2F-
L929 cells	NG\ZXZNCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		M173cFUh\GG7cx?=	Mlu5RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDtc5V{\SCOOUK5JINmdGy\|IHHmeIVzKDViZHH5d{BjgSCZU2StNUBie3OjeTygTWM2OCB;IECuNkDPxE1w	NGDwemY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEm1OlkyPSd-Mki5OVY6OTV:L3G+
KB-3-1 cells	NXPSZpZDSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=		MXu1JIRigXN?	MkDiRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiCNQj2zMVEh[2WubIOgZYZ1\XJiNTDkZZl{KGK7IGfTWE0yKGG\|c3H5MEBKSzVyIE2gNE4zKM7:TT6=	MkG1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh7NU[5NVUoRjJ6OUW2PVE2RC:jPh?=
MCF7 cells	MoPPRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?		NF;5N2k2KGSjeYO=	NVfuRpE1SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEWg[IF6eyCkeTDXV3QuOSCjc4PhfUwhUUN3MDC9JFEvQCEQvF2u	MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDl3NkmxOUc,Ojh7NU[5NVU9N2F-
FS4-LTM cells	MYnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		MojCNlQhcA>?	MU\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE[VND3MWG0h[2WubIOgZYZ1\XJiMkSgbJJ{KGK7IGfTWE0yKGG\|c3H5MEBKSzVyIE2gNk45KM7:TT6=	MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDl3NkmxOUc,Ojh7NU[5NVU9N2F-
Vero cells	NGjjbnFEgXSxdH;4bYNqfHliYYPzZZk>		NETL[oIzKGSjeYO=	Ml71R5l1d3SxeHnjbZR6KGGpYXnud5QhSW[{aXPhckBoemWnbjDtc45s\XliVnXyc{Bk\WyuczDh[pRmeiB{IHThfZMh[nliQ3XscHRqfGW{LVfsc{BtfW2rbnXzZ4VvfCClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OCB;IECuNFAzPCEQvF2u	MmrIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh7OUOxNFYoRjJ6OUmzNVA3RC:jPh?=
HepG2 cells	M2f5XGN6fG:2b4jpZ4l1gSCjc4PhfS=>	NUnmSJNjOTByIIXN	NGr4XXk{KGSjeYO=	M1vZ[mN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGG2IEGwNEB2VSCjZoTldkA{KGSjeYOgZpkhS2WubGTpeIVzNUeubzDseY1qdmW\|Y3XueEBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NEA:KDBwMEG4JO69VS5?	NWi5fnRMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki5PVMyODZpPkK4PVk{OTB4PD;hQi=>
NIH/3T3 cells	NYDPW3Y1S3m2b4TvfIlkcXS7IHHzd4F6		M1HOXFk3KGh?	MYDDfZRwfG:6aXPpeJkh[WejaX7zeEBud3W\|ZTDOTWgwO1R\|IHPlcIx{KGGodHXyJFk3KGi{czDifUBUWkJiYYPzZZktKEWFNUCgQUAxNjByODFOwG0v	Mn;uQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjlzOUe3N\|AoRjJ7MUm3O\|MxRC:jPh?=
518A2 cells	M4f1emN6fG:2b4jpZ4l1gSCjc4PhfS=>		NYXW[5E6QTZiaB?=	MU\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjC1NVhCOiClZXzsd{Bi\nSncjC5OkBpenNiYomgV3JDKGG\|c3H5MEBGSzVyIE2gNE4xOyEQvF2u	NXPWb5lKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmxPVc4OzBpPkK5NVk4PzNyPD;hQi=>
A549 cells	MkHKR5l1d3SxeHnjbZR6KGG\|c3H5		M1nsfFk3KGh?	NGXPdllEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFk3KGi{czDifUBUWkJiYYPzZZktKEWFNUCgQUAxNjB2IN88UU4>	M1rRZ\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MUm3O\|MxLz5{OUG5O\|c{ODxxYU6=
MCF7 cells	NHzNTo5EgXSxdH;4bYNqfHliYYPzZZk>		M3;OV\|k3KGh?	MojvR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC5OkBpenNiYomgV3JDKGG\|c3H5MEBGSzVyIE2gNE4yKM7:TT6=	M1;wU\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MUm3O\|MxLz5{OUG5O\|c{ODxxYU6=
A2780 cells	MWTDfZRwfG:6aXPpeJkh[XO\|YYm=		M3LTPFk3KGh?	NEnCR4JEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCOjd6MDDj[YxteyCjZoTldkA6PiCqcoOgZpkhW1KEIHHzd4F6NCCHQ{WwJF0hOC5zMjFOwG0v	MmDWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjlzOUe3N\|AoRjJ7MUm3O\|MxRC:jPh?=
HT-29 cells	M{DtT2N6fG:2b4jpZ4l1gSCjc4PhfS=>		M{H1eVk3KGh?	NFnu[GdEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXC1{OTDj[YxteyCjZoTldkA6PiCqcoOgZpkhW1KEIHHzd4F6NCCHQ{WwJF0hOC5zNTFOwG0v	MofUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjlzOUe3N\|AoRjJ7MUm3O\|MxRC:jPh?=
PC3 cells	MXrDfZRwfG:6aXPpeJkh[XO\|YYm=			NFPiT3hEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSzNiY3XscJMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhUUN3MDC9JFAvODF5IN88UU4>	NFHpVGM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUO4PVEzOid-MkmzPFkyOjJ:L3G+
HCT116 cells	MmDwR5l1d3SxeHnjbZR6KGG\|c3H5			M3zrWmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhEXDFzNjDj[YxteyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCLQ{WwJF0hOC5yNUWg{txONg>?	NFLaTHE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUO4PVEzOid-MkmzPFkyOjJ:L3G+
insect cells	MYDGeY5kfGmxbjDhd5NigQ>?		MVKzNEBucW6\|	MojiTY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCSRFfGVoJmfGFiZYjwdoV{e2WmIHnuJIlve2WldDDj[YxteyC3c3nu[{BWdGmpaIStVI9tgSCJQWTbSWF[MDF8MUqxLX1vKGG\|IIP1ZpN1emG2ZTDh[pRmeiB\|MDDtbY5{KGK7IFzBUmNGKG2ndHjv[EwhUUN3MDC9JFAvODByN{[g{txONg>?	M3OzfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NUS5PFM3Lz5{OUW0PVg{PjxxYU6=
Sf9 insect cells	MmfOSpVv[3Srb36gZZN{[Xl?		NYPEO4tbPjBibXnudy=>	MmjQTY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCNRGKg[ZhxemW\|c3XkJIlvKFOoOTDpcpNm[3RiY3XscJMhfXOrbnegWYxq\2i2LVPBS2FISUmHVFTLSXl[XF[NRDDhd{B{fWK\|dILheIUh[W[2ZYKgOlAhdWmwczDifUBNSU6FRTDt[ZRpd2RuIFnDOVAhRSByLkCwNlEh\|ryPLh?=	MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTV2OUizOkc,Ojl3NEm4N\|Y9N2F-
insect cells	NYLx[plsTnWwY4Tpc44h[XO\|YYm=		MWCxNEBucW6\|	NGTMOG9KdmirYnn0bY9vKG:oIILlZ49u[mmwYX70JIh2dWGwIGPyZ{BmgHC{ZYPz[YQhcW5iaX7z[YN1KGOnbHzzJJV{cW6pIGXsbYdpfC2Sb3z5JGdCXFuHQWmoNVoyQjFrXX6gZZMhe3Wkc4TyZZRmKGGodHXyJFExKG2rboOgZpkhVEGQQ1WgcYV1cG:mLDDJR\|UxKD1iMD6wNFUh\|ryPLh?=	NYH6U\|VjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm1OFk5OzZpPkK5OVQ6QDN4PD;hQi=>
insect cells	NXO4fIJqTnWwY4Tpc44h[XO\|YYm=		MXSxOUBucW6\|	MUHJcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IHj1cYFvKEOGS{GvR5lkdGmwIFKg[ZhxemW\|c3XkJIlvKGmwc3XjeEBk\WyuczD1d4lv\yCXbHnnbJQuS0[IS17JWnRRWlSSUGDTVWdMNWGvaXTlJIF{KHO3YoP0doF1\SCjZoTldkAyPSCvaX7zJIJ6KEyDTlPFJI1mfGixZDygTWM2OCB;IECuNFI2KM7:TT6=	NEfST\|A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUW0PVg{Pid-Mkm1OFk5OzZ:L3G+
insect cells	NGCxU2pHfW6ldHnvckBie3OjeR?=		NUHub3k2OTVibXnudy=>	MknoTY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCFRFuxM2N6[2yrbjDCJIV5eHKnc4Pl[EBqdiCrboPlZ5Qh[2WubIOgeZNqdmdiVXzp[4h1NUOIRlvOTXZVWFKWUGDQV3FIUy2jbXnk[UBieyC\|dXLzeJJifGViYX\0[ZIhOTVibXnud{BjgSCOQV7DSUBu\XSqb3SsJGlEPTBiPTCwMlAzPSEQvF2u	MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTV2OUizOkc,Ojl3NEm4N\|Y9N2F-
Sf9 insect cells	MXHGeY5kfGmxbjDhd5NigQ>?		NEnmUG4yPSCvaX7z	NV\SVoxiUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDGcJQyKGW6cILld5Nm\CCrbjDT[lkhcW6\|ZXP0JINmdGy\|IIXzbY5oKFWuaXfoeE1VUyCyZYD0bYRmKGG\|IIP1ZpN1emG2ZTDh[pRmeiBzNTDtbY5{KGK7IFzBUmNGKG2ndHjv[EwhUUN3MDC9JFAvODN3IN88UU4>	M4HKW\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NUS5PFM3Lz5{OUW0PVg{PjxxYU6=
Sf21 insect cells	NVjGeGw6TnWwY4Tpc44h[XO\|YYm=		NUXYU2ZsOTVibXnudy=>	MmTiTY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCDdYLvdoEuSSCneIDy[ZN{\WRiaX6gV4YzOSCrboPlZ5Qh[2WubIOgeZNqdmdiVXzp[4h1NVKUUmPMUGUh[XNic4Xid5Rz[XSnIHHmeIVzKDF3IH3pcpMh[nliTFHOR2UhdWW2aH;kMEBKSzVyIE2gNE4xOzlizszNMi=>	MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTV2OUizOkc,Ojl3NEm4N\|Y9N2F-
insect cells	MVvGeY5kfGmxbjDhd5NigQ>?		NXPK[3FpPjBibXnudy=>	NXfIXY1nUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDBT3QyKGW6cILld5Nm\CCrbjDpcpNm[3RiY3XscJMhfXOrbnegR3JGSnSrZHWgZZMhe3Wkc4TyZZRmKGGodHXyJFYxKG2rboOgZpkhVEGQQ1WgcYV1cG:mLDDJR\|UxKD1iMD6wOVYh\|ryPLh?=	NF6ycIM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUW0PVg{Pid-Mkm1OFk5OzZ:L3G+
Sf9 insect cells	NWjQN\|ZmTnWwY4Tpc44h[XO\|YYm=		M{nDU\|YxKG2rboO=	MV\Jcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IHj1cYFvKE[DSzDlfJBz\XO\|ZXSgbY4hW2Z7IHnud4VkfCClZXzsd{B2e2mwZzDVcIlocHRvVFugdIVxfGmmZTDhd{B{fWK\|dILheIUh[W[2ZYKgOlAhdWmwczDifUBNSU6FRTDt[ZRpd2RuIFnDOVAhRSByLkC2NkDPxE1w	MnHkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl3NEm4N\|YoRjJ7NUS5PFM3RC:jPh?=
insect cells	MlHRSpVv[3Srb36gZZN{[Xl?		MV[2NEBucW6\|	NFmzVJJKdmirYnn0bY9vKG:oIILlZ49u[mmwYX70JIh2dWGwIFHCUEBmgHC{ZYPz[YQhcW5iaX7z[YN1KGOnbHzzJJV{cW6pIGXsbYdpfC2WSzDw[ZB1cWSnIHHzJJN2[nO2cnH0[UBi\nSncjC2NEBucW6\|IHL5JGxCVkOHIH3leIhw\CxiSVO1NEA:KDBwMkmg{txONg>?	M4D4OlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NUS5PFM3Lz5{OUW0PVg{PjxxYU6=
insect cells	NWDXfIpiTnWwY4Tpc44h[XO\|YYm=		Ml7tOlAhdWmwcx?=	M4jkcWlvcGmkaYTpc44hd2ZicnXjc41jcW6jboSgbJVu[W5iYz3NSXQh\XiycnXzd4VlKGmwIHnud4VkfCClZXzsd{B2e2mwZzDVcIlocHRvQ1HHRWdCUUWWRFvFXXlVXkuGIHHzJJN2[nO2cnH0[UBi\nSncjC2NEBucW6\|IHL5JGxCVkOHIH3leIhw\CxiSVO1NEA:KDBwM{Gg{txONg>?	NXfXbZRURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm1OFk5OzZpPkK5OVQ6QDN4PD;hQi=>
PC3 cells	NE\0d\|VEgXSxdH;4bYNqfHliYYPzZZk>		M1zMNlczKGh?	NYHWeYtRS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWEN\|IHPlcIx{KGGodHXyJFczKGi{czDifUBUWkJiYYPzZZktKEmFNUCgQUAxNjB\|OTFOwG0v	M2PUbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NUW4NVE6Lz5{OUW1PFEyQTxxYU6=
Sf9 cells	NYPi[5lpTnWwY4Tpc44h[XO\|YYm=		MWq0OUBucW6\|	NXHJW4RRUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDDMZRmem2rbnHsJGhqey22YXfn[YQwVi22ZYLtbY5idCCJU2SteIFo\2WmIFXHSnIhMDZ4ODD0c{AyOjFyIILld4llfWW\|KTDlfJBz\XO\|ZXSgbY4h[mGldXzveolzfXNiaX7m[YN1\WRiU3[5JINmdGy\|IIXzbY5oKFCxbImtLGdtfSxiVInyLUBieyC\|dXLzeJJifGVibXXhd5Vz\WRiYX\0[ZIhPDVibXnueZRmeyCkeTDLbY5ie2VvR3zvJIx2dWmwZYPj[Y51KGG\|c3H5MEBKSzVyIE2gNE4xPDdizszNMi=>	NFLDNHE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUmwNlcyQSd-Mkm5NFI4OTl:L3G+
Sf9 cells	NWjBcGRmTnWwY4Tpc44h[XO\|YYm=		NG\SRm81PSCvaX7z	M1;le2lvcGmkaYTpc44hd2ZicnXjc41jcW6jboSgbJVu[W5iTj30[ZJucW6jbDDHV3QufGGpZ3XkJGhGWjJiKE[3PUB1dyBzMkW1JJJme2mmdXXzLUBmgHC{ZYPz[YQhcW5iYnHjeYxwfmm{dYOgbY5n\WO2ZXSgV4Y6KGOnbHzzJJV{cW6pIGDvcJkuMEeudTygWJlzMSCjczDzeYJ{fHKjdHWgcYVie3W{ZXSgZYZ1\XJiNEWgcYlvfXSnczDifUBMcW6jc3WtS4xwKGy3bXnu[ZNk\W62IHHzd4F6NCCLQ{WwJF0hOC5yNkC4JO69VS5?	NFj3WnI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUmwNlcyQSd-Mkm5NFI4OTl:L3G+
HT-29 cells	MnPaSpVv[3Srb36gZZN{[Xl?		NGnhTVc{KGh?	M4LsbWlvcGmkaYTpc44hd2ZibXn0c4Npd26mcnnhcEBu\W2kcnHu[UBxd3SnboTpZYwhcW5iaIXtZY4hUFRvMkmgZ4VtdHNiYX\0[ZIhOyCqcoOgZpkhUkNvMTDzeIFqdmmwZzDiZZNm\CCobIXvdoV{[2WwY3WgZZN{[XluIFnDOVAhRSByLkCyJO69VS5?	NIL4cFM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9\|MEC1O\|E2PSd-M{CwOVcyPTV:L3G+
Sf9 cells	MlfzSpVv[3Srb36gZZN{[Xl?			NIrrNldKdmirYnn0bY9vKG:oIF6teIVzdWmwYXygSmxCTy22YXfn[YQhcHWvYX6g[pVtdC2uZX7neIghS0SNMUKgLFEhfG9iMUS5NEBz\XOrZIXld{kwVi22ZYLtbY5idCCKaYOteIFo\2WmIFP5Z2shMDFidH:gOVgxKHKnc3nkeYV{MSCneIDy[ZN{\WRiaX6gV4Y6KGOnbHzzJIF{e2W\|c3XkJIF{KHKnZIXjeIlwdiCrbjDBWHAu\GWyZX7k[Y51KFWOaXfoeE01TS2EUEGgLHRpejN5L2TodlQ3MSC\|dXLzeJJifGVicHXweIll\SCyaH;zdIhwenmuYYTpc44heHJuIFnDOVAhRSByLkC1N{DPxE1w	NXHaWINVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{CwOlc{PThpPkOwNFY4OzV6PD;hQi=>
Sf9 cells	NGH2NIJHfW6ldHnvckBie3OjeR?=			MXLJcohq[mm2aX;uJI9nKE5vdHXycYlv[WxiRlzBS{11[WepZXSgbJVu[W5iZoXscE1t\W6pdHigR2RMOTJiKEGgeI8hOTR7MDDy[ZNq\HWnczmvUk11\XKvaX7hcEBJcXNvdHHn[4VlKEO7Y1ugLFEhfG9iNUiwJJJme2mmdXXzLUBmgHC{ZYPz[YQhcW5iU3[5JINmdGy\|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiCDVGCt[IVx\W6mZX70JHVNcWeqdD20SU1DWDFiKGTodlM4N1SqckS2LUB{fWK\|dILheIUheGWydHnk[UBxcG:\|cHjvdplt[XSrb36gdJItKEmFNUCgQUAxNjB3MzFOwG0v	M{PQflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyME[3N\|U5Lz5\|MEC2O\|M2QDxxYU6=
Sf9 cells	M2XIcGZ2dmO2aX;uJIF{e2G7			M1\xXWlvcGmkaYTpc44hd2ZiTj30[ZJucW6jbDDGUGFINXSjZ3fl[EBpfW2jbjDmeYxtNWynbnf0bEBETEtzMzCoNUB1dyBzNUGyJJJme2mmdXXzLU9PNXSncn3pcoFtKEircz30ZYdo\WRiQ4njT{ApOSC2bzC1PFAhemW\|aXT1[ZMqKGW6cILld5Nm\CCrbjDT[lkh[2WubIOgZZN{\XO\|ZXSgZZMhemWmdXP0bY9vKGmwIFHUVE1l\XCnbnTlcpQhXUyrZ3j0MVRGNUKSMTCoWIhzOzdxVHjyOFYqKHO3YoP0doF1\SCyZYD0bYRmKHCqb4PwbI9zgWyjdHnvckBxeixiSVO1NEA:KDBwMEW3JO69VS5?	MmnhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzByNkezOVgoRjNyME[3N\|U5RC:jPh?=
Sf9 cells	Mne3SpVv[3Srb36gZZN{[Xl?			MmWyTY5pcWKrdHnvckBw\iCQLYTldo1qdmGuIF\MRWcufGGpZ3XkJIh2dWGwIH\1cIwudGWwZ4ToJGNFUzF\|IDixJJRwKDF3MUKgdoV{cWS3ZYOpM24ufGW{bXnuZYwhUGm\|LYTh[4dm\CCFeXPLJEgyKHSxIEW4NEBz\XOrZIXld{kh\XiycnXzd4VlKGmwIGPmPUBk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iQWTQMYRmeGWwZHXueEBWVGmpaIStOGUuSlBzIDjUbJI{Py:WaIK0Okkhe3Wkc4TyZZRmKHCncITp[IUheGixc4Doc5J6dGG2aX;uJJBzNCCLQ{WwJF0hOC5yNUeg{txONg>?	NVHXOXNkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{CwOlc{PThpPkOwNFY4OzV6PD;hQi=>
HCT116 cells	M3HSTGN6fG:2b4jpZ4l1gSCjc4PhfS=>		NVn2UlE2PDhiaB?=	MXrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[XO\|ZYPz[YQh[XNiZHXjdoVie2ViaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwMEOg{txONg>?	NIm1Unc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9\|MEGwOlI6OSd-M{CxNFYzQTF:L3G+
Huh7.5 cells	M{XuemN6fG:2b4jpZ4l1gSCjc4PhfS=>		M3XoNFQ5KGh?	NUPO[IF[S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUHWqNz61JINmdGy\|IHHzd4V{e2WmIHHzJIRm[3KnYYPlJIlvKGOnbHygeoli[mmuaYT5JIFnfGW{IES4JIhzeyCkeTDNWHQh[XO\|YYmsJGlEPTBiPTCwMlYh\|ryPLh?=	Mk\2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzBzME[yPVEoRjNyMUC2NlkyRC:jPh?=
K562 cells	M4PsNWN6fG:2b4jpZ4l1gSCjc4PhfS=>		MVG0PEBp	M33aNGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGs2PjJiY3XscJMh[XO\|ZYPz[YQh[XNiZHXjdoVie2ViaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFwNzFOwG0v	M3u3WlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyMUC2NlkyLz5\|MEGwOlI6OTxxYU6=
LO2 cells	NHfnVJREgXSxdH;4bYNqfHliYYPzZZk>		MlL2OFghcA>?	NH;4NHhEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBNVzJiY3XscJMh[XO\|ZYPz[YQh[XNiZHXjdoVie2ViaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDlwNTFOwG0v	NInIU2U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9\|MEGwOlI6OSd-M{CxNFYzQTF:L3G+

... Click to View More Cell Line Experimental Data

Assay

Methods	Test Index	PMID
Western blot	FAK / RIP; PubMed: 15121855 Mol Cell Biol Western blot (WB) analysis of BT-20 and BT-474 lysates treated with staurosporine (200 nM). Control cells were treated with dimethyl sulfoxide for 18 h. p-Akt / Akt / PARP /Cleaved PARP; PubMed: 24174874 Int J Nanomedicine Western blot analysis for Akt, P-Akt, and cleaved poly(ADP-ribose) polymerase. U87 cells were incubated with 200 nM, 10 nM, and 0.1 nM of staurosporine encapsulated in liposomes and staurosporine for 32 hours. Ambra1; PubMed: 24587252 PLoS One SW620 cells treated with various doses of staurosporine for 6 h. Ambra1 levels were measured by Western blot.	15121855 24174874 24587252
Growth inhibition assay	Cell viability; PubMed: 25215174 Oxid Med Cell Longev Staurosporine reduces cerebellar astrocytes viability. (a) Cerebellar astrocytes were treated with staurosporine 0.1 μM, 0.25 μM, and 0.5 μM for 24 h and the cell viability was measured by MTT transformation. (b) Cerebellar astrocytes were treated with staurosporine 0.5 μM for 6, 12, and 24 h and the cell viability was measured by MTT transformation. Data are presented as mean ± SEM of four independent experiments. ∗ is significantly different from control (P < 0.05).	25215174
Immunofluorescence	Phalloidin / Type II collagen; PubMed: 22684244 Exp Mol Med Cell were cultured in the absence (a-f) or presence of staurosporine (STSN, 5 × 10-9M) or cytochalasin D (CD, 1 µg/ml) for 1 (upper panel) or 2 (lower panel) days at low density and stained for F-actin (Phalloidin) and type II collagen (Type II). STSN: Staurosporine. Tubulin / Actin; PubMed: 25215174 Oxid Med Cell Longev Morphological changes of astrocytes induced by St are evidenced by the rearrangement of cytoskeletal proteins. Astrocytes were treated with St (0.5 μM) for 12 hours and then were labelled with rhodamine-phalloidin or immunostained for tubulin. Representative images of phase contrast, rhodamine-phalloidin, and tubulin are shown in control and St treated astrocytes. Scale bar represents 50 μm. FAK 4.47; PubMed: 15121855 Mol Cell Biol BT-20 or BT-474 cell culture were plated on six-well plates and were treated with staurosporine (200 nM) after 24 h. After 6 h of treatment, cells were immunostained with anti-FAK 4.47 antibody (white arrowheads mark some focal adhesions). cleaved-caspase 3; PubMed: 19840952 Cardiovasc Res Representative images (×1000 magnification) showing vehicle treated (C) and staurosporine treated (D) cells stained with anti-cleaved caspase 3 antibody and DAPI. Annexin; PubMed: 15140398 Neoplasia Induction of apoptosis with staurosporine resulting in activation of the ICE-NIRF probe. Gli36 cells were treated with 50 µM staurosporine for 24 hours (A-C) or with the same percentage of DMSO (0.01%) to which experimental wells were exposed (D-488nm laser, E-633nm laser and F-bright field). To examine the role of caspase-1 in staurosporine-induced apoptosis and probe activation, cells were coincubated in caspase-1 inhibitor (10 µM) and staurosporine (G-I). Staurosporine induces apoptosis, indicated by the positive annexin staining viewed with the 488-nm laser (A), which colocalized with activated probe viewed with the 633-nm laser (B). Coincubation of the caspase-1 inhibitor with staurosporine did not completely block apoptosis, indicated by the relatively higher number of apoptotic cells stained with annexin (G), as those that activated the probe (H). Magnification, x 40; scale bar, 50 µM. Pyk2; PubMed: 19880522 J Biol Chem Pyk2 translocates to the nucleus upon staurosporine addition to ID8 cells. Confocal immunofluorescent analysis of endogenous Pyk2 upon DMSO (control) or 1 μm staurosporine addition for 2 h. The scale bar is 10 μm.	22684244 25215174 15121855 19840952 15140398 19880522

体内研究

在局部贫血前，使用Staurosporine(0.1-10 ng)预处理局部贫血沙鼠和大鼠模型，可防止神经元损伤，这种作用存在剂量依赖性，说明CAl锥体细胞死亡涉及PKC。^[2]

激酶实验： ^[1]	- 合并 Enzyme assay and binding assay: Protein kinase C is assayed in a reaction mixture (0.25 mL) containing 5 μmol of Tris/HCl, pH 7.5, 2.5 μmol of magnesium acetate, 50 μg of histone II S, 20 μg of phosphatidylserine, 0.88 μg of diolein, 125 nmol of CaCl₂, 1.25 nmol of [γ-³²]ATP (5-10 × 10⁴ cpm/nmol) and 5 μg of partially purified enzyme. The binding of [³H]PDBu to protein kinase C is determined: Reaction mixture (200 μL contained 4 μmo1 of Tris/malate, pH 6.8, 20 μmol of KCl, 30 nmol of CaC1₂, 20 μg of phosphatidylserine, 5 μg of partially purified protein kinase C, 0.5% (final concentration) of DMSO,10 pmol of [³H]PDBu (l-3 × 10⁴ cpm/pmol) and 10 μL of various amounts of Staurosporine.
细胞实验：^[4]	- 合并 Cell lines: PC12 Concentrations: 溶于DMSO,终浓度为1 μM Incubation Time: ~32 小时 Method: 使用Staurosporine处理细胞32小时。细胞在4%多聚甲醛中混合，然后使用DNA结合染料Hoechst 33342染色。在荧光照明下观察细胞，测定凋亡细胞百分数。 (Only for Reference)
动物实验：^[2]	- 合并 Animal Models: 短暂局部贫血的雄性Mongolian沙鼠或雄性 Wistar大鼠 Dosages: ~10 ng Administration: 定向处理到海马双边CA₁子域 (Only for Reference)

参考文献

- 合并

溶解度 (25°C)

体外	DMSO	4 mg/mL (8.57 mM)
	Water	Insoluble
	Ethanol	Insoluble

* 溶解度检测是由Selleck技术部门检测的，可能会和文献中提供的溶解度有所差异，这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据 Download Staurosporine (AM-2282) SDF

分子量	466.53
化学式	C₂₈H₂₆N₄O₃
CAS号	62996-74-1
储存条件	3年-20°C 粉状 2年-80°C 溶于溶剂
别名	Antibiotic AM-2282, STS

动物体内配方计算器 (澄清溶液)

第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量）

给药剂量

mg/kg

动物平均体重

每只动物给药体积

动物数量

只

第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系Selleck为您提供正确的澄清溶液配方）

% DMSO+ % + % Tween 80+ % ddH₂O

计算重置

计算结果:

工作液浓度： mg/ml；

DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，注：如该浓度超过该批次药物DMSO溶解度，请先联系Selleck）；

体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL ddH₂O，混匀澄清。

注意：1. 首先保证母液是澄清的；
2. 一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。

计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为:

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

质量

浓度

体积

分子量
=

×

×

*在配置溶液时，请务必参考Selleck产品标签上、SDS / COA（可在Selleck的产品页面获得）批次特异的分子量使用本工具。

稀释计算器

用本工具协助配置特定浓度的溶液，使用的计算公式为：

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入输出 )

C1

V1

C2

V2
×

=

×

在配置溶液时，请务必参考Selleck产品标签上、SDS / COA（可在Selleck的产品页面获得）批次特异的分子量使用本工具。.

连续稀释计算器方程

连续稀释
初始浓度:
稀释倍数:

计算结果

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):

分子量计算器

通过输入化合物的化学式来计算其分子量：

注：化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量	浓度	体积	分子量
=	×	×
计算

技术支持

在订购、运输、储存和使用我们的产品的任何阶段，您遇到的任何问题，均可以通过拨打我们的热线电话400-668-6834，或者技术支持邮箱tech@selleck.cn，直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题，请给我们留言。

研究领域

产品类型

定制您的化合物库

Staurosporine (AM-2282)

客户使用Selleck生产的Staurosporine (AM-2282)发表文献96篇：

产品安全说明书

Antineoplastic and Immunosuppressive Antibiotics抑制剂选择性比较

生物活性

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

参考文献

溶解度 (25°C)

化学数据 Download Staurosporine (AM-2282) SDF

动物体内配方计算器 (澄清溶液)

计算器

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

稀释计算器

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

连续稀释计算器方程

连续稀释

计算结果

分子量计算器

总分子量：g/mol

摩尔浓度计算器

技术支持