Caffeic Acid Phenethyl Ester

For research use only. Not for use in humans.

目录号:S7414 别名: CAPE, Phenylethyl Caffeate 中文名称:咖啡酸苯乙酯

Caffeic Acid Phenethyl Ester Chemical Structure

CAS No. 104594-70-9

Caffeic acid phenethyl ester (CAPE, Phenylethyl Caffeate)是强效的特异性NF-κB活化抑制剂,也能够表现出抗氧化、免疫调节和抗炎活动。

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客户使用Selleck生产的Caffeic Acid Phenethyl Ester发表文献37篇:

产品安全说明书

NF-κB抑制剂选择性比较

生物活性

产品描述 Caffeic acid phenethyl ester (CAPE, Phenylethyl Caffeate)是强效的特异性NF-κB活化抑制剂,也能够表现出抗氧化、免疫调节和抗炎活动。
靶点
NF-κB [1]
体外研究

Caffeic acid phenethyl ester能够通过抑制p65的入核转运来抑制佛波酯,神经酰胺,强心酸过氧化氢等诱导的NF-kB的激活。[1] 在一系列的肿瘤细胞系中,Caffeic acid phenethyl ester具有抗增殖的活性,其对26-L5, B16-BL6恶性瘤, 人类HT-1080的 EC50 分别是 1.76, 3.16, 13.7,和44.0 μM。[2] Caffeic acid phenethyl ester通过抑制ROS的形成和抑制半胱氨酸天冬氨酸蛋白酶的活性发挥抗凋亡的作用。Caffeic acid phenethyl ester通过抑制NF-kB信号通路来减弱LPS诱导的炎症和LPS诱导的HSCs细胞对细胞因子的敏感性。[4]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
mouse RAW264.7 cells Mn3oSpVv[3Srb36gZZN{[Xl? NFn5[3EzPCCq NGi2NVZKdmirYnn0bY9vKG:oIFzQV{1qdmS3Y3XkJI5qfHKrYzDvfIll\SCycn;keYN1cW:wIHnuJI1wfXOnIGLBW|I3PC55IHPlcIx{KGG|c3Xzd4VlKGG|IH7peJJqfGViYXPjeY12dGG2aX;uJIFldWmwaYP0[ZJm\CBzIHjyJIJm\m:{ZTDMVHMh[2ijbHzlcodmKGGwZDDt[YF{fXKnZDDh[pRmeiB{NDDodpMh[nliR4Lp[ZN{KHKnYXflcpQh[XO|YYmsJGVEPTB;MD6xPVMh|ryP M2LiN|E5PjZ5M{Kw
mouse 26-L5 cells MnywVJJwdGmoZYLheIlwdiCjc4PhfS=> MYO3NkBp NWiwVGVESW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBud3W|ZTCyOk1NPSClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBGSzVyPUCuN{DPxE1? MoTlNVIxOjd5M{m=
human HeLa cells MVrQdo9tcW[ncnH0bY9vKGG|c3H5 MWq3NkBp NYrPTGU1SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGVEPTB;Mj6zOkDPxE1? NIO4dY0yOjB{N{ezPS=>
human Bewo cells MnrvSpVv[3Srb36gZZN{[Xl? NELKN2FCdnSrdIXtc5Ih[WO2aY\peJkh[WejaX7zeEBpfW2jbjDC[ZdwKGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[gZ4VtdCCpcn;3eIgh[nliTWTUJIF{e2G7LDDJR|UxRTJwOU[g{txO NYP6[WVlOjVzNkC4N|c>
mouse J774.1 cells MYXGeY5kfGmxbjDhd5NigQ>? M1:1SFI1KGh? NUXxT29pUW6qaXLpeIlwdiCxZjDMVHMucW6mdXPl[EBPVyCycn;keYN1cW:wIHnuJI1wfXOnIFq3O|QvOSClZXzsd{Bi\nSncjCyOEBpenNiYomgS5Jq\XO|IILlZYdmdnRiYYPzZZktKEmFNUC9OE45KM7:TR?= NFnvZYgyPTl5NE[wPC=>
human Bel7402 cells M3TWVWN6fG:2b4jpZ:Kh[XO|YYm= M4jnfGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGJmdDd2MEKgZ4VtdHNiYomgUXRVKGG|c3H5MEBKSzVyPUWuOUDPxE1? Mke5NVg6PTJ2MkC=
human LNCAP cells MV\GeY5kfGmxbjDhd5NigQ>? M1rKSVI1KGh? MXPBcpRq[W6mcn;n[Y5q[yCjY4Tpeol1gSCrbjDoeY1idiCOTlPBVEBk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iRFjUMZN1cW23bHH0[YQhWFODIILlcIVie2ViYX\0[ZIhOjRiaILzJIJ6KEWOSWPBMEBKSzVyPU[uNkBvVQ>? NU\pNotrOjRyOECxNFU>
mouse BV2 cells MYTGeY5kfGmxbjDhd5NigQ>? M4PUSVI1KGh? M3;VU2lvcGmkaYTpc44hd2Zibnn0dolkKG:6aXTlJJBzd2S3Y4Tpc44hcW5iTGDTMZN1cW23bHH0[YQhdW:3c3WgRnYzKGOnbHzzJJRz\WG2ZXSgN{BpenNiYnXmc5JmKEySUzDh[IRqfGmxbjDt[YF{fXKnZDDh[pRmeiB{NDDodpMh[nliR4Lp[ZN{KGG|c3H5MEBKSzVyPU[uOEDPxE1? M4LoVVI{QDdyN{Cw
mouse B16-BL6 cells NWjsfXR3WHKxbHnm[ZJifGmxbjDhd5NigQ>? M37kc|czKGh? MUHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IH3veZNmKEJzNj3CUFYh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygSWM2OD14Lke5JO69VQ>? NVT1[3hQOTJyMke3N|k>
HUVEC cells NIrrbJpEgXSxdH;4bYPDqGG|c3H5 MYCxPEBp MlO3R5l1d3C{b4TlZ5RqfmViYXP0bZZqfHliYXfhbY5{fCCKMl:yMYlv\HWlZXSgc5hq\GG2aY\lJJN1emW|czDpckBJXV[HQzDj[YxteyCjZoTldkAyQCCqcoOgZpkhS2WubD3UbZRmeiCEbIXlJIF{e2G7 M2PlflIxPTl6OEm0
human HT1080 cells NGn6XVFRem:uaX\ldoF1cW:wIHHzd4F6 Mk\XO|IhcA>? NH7kXGdCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjUNVA5OCClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBGSzVyPUmuOUDPxE1? M1T6T|EzODJ5N{O5
human HL60 cells NUmzfIFiS3m2b4TvfIlkyqCjc4PhfS=> MlLjO|IhcA>? NHL4OXFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJVDZyIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUC9PU45KM7:TR?= MknVNlA3PzN5Mke=
human LS 174T cells MoXVR5l1d3SxeHnjxsBie3OjeR?= MUG3NkBp MnjSR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUHMhOTd2VDDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{[wQVkvQSEQvF2= MVWyNFY4Ozd{Nx?=
human SGC7901 cells M1TKNGZ2dmO2aX;uJIF{e2G7 NHTh[GlCdnSrdIXtc5Ih[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTS2M4QTBzIHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4Yh[2WubDDndo94fGhiYomgUXRVKGG|c3H5MEBKSzVyPUG0MlI3KM7:TR?= MVmyOVE3ODh|Nx?=
human Bel7404 cells MmTjR5l1d3SxeHnjxsBie3OjeR?= NFzuTIk4OiCq MkC4R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRoVtPzRyNDDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwQVE1NjVizszN NWrqbmZlOjB4N{O3Nlc>
human BGC823 cells Mn;pR5l1d3SxeHnjxsBie3OjeR?= NEXESVE4OiCq M1vRVmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGJISzh{MzDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwQVE6NjNizszN M1fCSlIxPjd|N{K3
human HO8910 cells M{OxV2N6fG:2b4jpZ:Kh[XO|YYm= NVjSeHduPzJiaB?= MlTlR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTG85QTFyIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUC9NlUvPSEQvF2= MV2yNFY4Ozd{Nx?=
human MCF7 cells Mn3PR5l1d3SxeHnjxsBie3OjeR?= NX;h[2lYS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTB;Mk[uO{DPxE1? M4HjdFE5QTV{NEKw
human A549 cells NGD6VHZEgXSxdH;4bYPDqGG|c3H5 M1exflczKGh? M{\2RmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3ME2yOk45KM7:TR?= MYeyNFY4Ozd{Nx?=
human LNCAP cells M2fNOGN6fG:2b4jpZ:Kh[XO|YYm= NELhSGozPCCq M2fwZWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGxPS0GSIHPlcIx{KGG|c3Xzd4VlKGG|IILl[JVkfGmxbjDpckBk\WyuII\pZYJqdGm2eTDh[pRmeiB{NDDodpMh[nliV2PUMVEh[XO|YYmsJGlEPTB;M{OuO{DPxE1? M{XoO|I1ODhyMUC1
human HeLa cells MVTGeY5kfGmxbjDhd5NigQ>? Mlz1RY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXMZUBk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKG:oIHPlcIwh\3Kxd4ToJIJ6KE2WVDDhd5NigSxiSVO1NF0{Py57ODFOwG0> M2C1ZlI2OTZyOEO3
human HepG2 cells NVPWVY5RTnWwY4Tpc44h[XO|YYm= MlPDRY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXwS|Ih[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDj[YxtKGe{b4f0bEBjgSCPVGSgZZN{[XluIFnDOVA:PDBwOEeg{txO NGO4XVYzPTF4MEizOy=>
human ECA109 cells M3PVemN6fG:2b4jpZ:Kh[XO|YYm= NGLuZVM4OiCq MlXlR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gSWNCOTB7IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUC9OFIvPiEQvF2= NXe2VGFyOjB4N{O3Nlc>
human BCG823 cells NHnpWIdEgXSxdH;4bYPDqGG|c3H5 M2mxNGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGJETzh{MzDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTB;NESuOkDPxE1? NEfrR5YyQDl3MkSyNC=>
human KB cells MnLyR5l1d3SxeHnjxsBie3OjeR?= MkHqO|IhcA>? MVnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDLRkBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxRTR3LkKg{txO NVzNOZNOOjB4N{O3Nlc>
human K562 cells MnLJR5l1d3SxeHnjxsBie3OjeR?= MYK3NkBp MV7DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDLOVYzKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTB;NE[g{txO NF;LSHgzODZ5M{eyOy=>
rat VSMC NWP5V3dRTnWwY4Tpc44h[XO|YYm= MX21JO69VQ>? M12zWVMxKG2rboO= MXzE[YNz\WG|ZTDpckBqdnS{YXPlcIx2dGG{IGLPV{Bt\X[nbDDpckBRTEeILYP0bY12dGG2ZXSgdoF1KF[VTVOgZZQhPSC3TTDwdoV1emWjdHXkJJdqfGhiY3;tdI92dmRiZn;yJFMxKG2rboOgcYVie3W{ZXSgZYZ1\XJidYCgeI8hOjNiaILzJI9nKHCxc4Sgd5RqdXWuYYTpc44hfXOrbnegTFJFS0ZiYomg[oxwfyCleYTvcYV1emmlIHHuZYx6e2m| NHHPVm8zOTJ4NUW1OC=>
rat PC12 cells MofPSpVv[3Srb36gZZN{[Xl? NFvTPVAzNjVizszN MWGzJIg> NWHITplHVmW3cn;wdo91\WO2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgTFJQOi2rbnT1Z4VlKGSjbXHn[UBqdiC{YYSgVGMyOiClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJZq[WKrbHn0fUBifCB{LkWgeW0heHKnaX7jeYJifGWmIH\vdkA{KGi{czDmc4xtd3enZDDifUBJOk9{IHPoZYxt\W6pZTDt[YF{fXKnZDDh[pRmeiB3IHjyd{BjgSCPVGSgZZN{[Xl? NYO1eHlPOjR4OUezN|U>

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
p-p65 / CDH6 / RUNX2 / E-cadherin / N-cadherin / Vimentin / Slug / Snail ; 

PubMed: 29284791     


c/ Effect of Caffeic acid phenethyl ester on the expression of EMT markers, CDH6 and RUNX2 detected by western blotting analysis. e/ Effect of Caffeic acid phenethyl ester on the expression of EMT markers, CDH6 and RUNX2.

Nrf2; 

PubMed: 28275300     


A: HSC-T6 cells were treated with 5 μmol/L, 10 μmol/L and 15 μmol/L CAPE for 24 h. Nrf2 mRNA and cytosol and nuclear protein expression levels were investigated using real-time PCR and Western blot, respectively

AKT / AKT1 / AKT2 / AKT3 / p-AKT / FOXO1 / FOXO3a / p-FOXO1 / p-FOXO3a / Skp2 / p27(Kip) / Cyclin D1 / Rb / p-Rb ; 

PubMed: 23615471     


Effects of CAPE treatment on the abundance and phosphorylation status of signaling proteins. Protein expression of total Akt, Akt1, Akt2, Akt3, phospho-Akt Ser473, phospho-Akt Thr308, GSK3β, Rb, phospho-Rb Ser807/811, cyclin D1, and Skp2, FOXO1, FOXO3a, phospho-FOXO1 Thr24, phospho-FOXO3a Thr32, NF-κB, phospho-NF-κB Ser536, p27(Kip), and β-actin in TW2.6 cells treated with 0, 50, or 100 μM CAPE for 48 h were assayed by Western blotting. Experiments were repeated three times.

29284791 28275300 23615471
Immunofluorescence
NF-κB; 

PubMed: 29284791     


NF-κB localization detected by IF assay in C666-1 cells when treated with Caffeic acid phenethyl ester. DMSO was the negative control. Green, p65; blue, H33342 staining (nuclei). In-NF-κB represents NF-κB inhibitor (the Caffeic acid phenethyl ester)

29284791
Growth inhibition assay
Cell number; 

PubMed: 23615471     


Effect of caffeic acid phenethyl ester (CAPE) on viability and proliferation of TW2.6 oral cancer cells. TW2.6 oral cancer cells were treated with increasing concentrations of CAPE for 24, 48, or 96 h and determined by Hoechst dye 33258-based 96-well proliferation assay (A) or by MTT (3,4,5-dimethylthiazol-2-yl)-2-5-diphenyltetrazolium bromide) 96-well assay (B), respectively, as described in Material and Methods. Cell numbers were normalized to control (DMSO treatment) of each treatment period. The mean and standard deviation represented the average and standard deviation respectively of the results from all 36 wells in the three experiments. Asterisk *** represents statistically significant difference p < 0.001 between the treated group and the control group.

23615471
体内研究 C57BL/6 and BALB/c小鼠腹腔内注射10毫克/千克Caffeic acid phenethyl ester能够抑制在路易斯肺细胞癌,结肠癌,和黑色素瘤的生长和肿瘤的血管新生。[5]在动物体内(5, 10, 20 mg/kg) 的Caffeic acid phenethyl ester通过减少胸腺的重量和胸腺和脾的孔性而具有免疫调节的作用。[6]

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

细胞实验:

[2]

- 合并
  • Cell lines: 小鼠结肠 26-L5, 小鼠B16-BL6黑色素瘤,人类HT-1080 纤维肉瘤和人类肺 A549 腺癌细胞系。
  • Concentrations: ~200 μM
  • Incubation Time: 3天
  • Method:

    人HT-1080纤维肉瘤,人肺癌A549腺癌细胞和鼠B16-BL6黑色素瘤细胞在含有10%的血清,0.1%碳酸盐,和2mM的谷氨酰胺的EMEM培养基中培养。鼠结肠癌细胞 B16-BL6用含有相同添加成分的RPMI中培养。除了A-549以外,这些都是有高度侵染能力的细胞系。细胞存活实验采用标准的MTT方法。简单的说,对数生长的细胞收集以后以2000个每孔的密度种植于96孔板。24小时孵育后,用含有不同浓度的样品的100ul培养基处理细胞,5%的二氧化碳37度条件下培养72小时。加入MTT3小时以后用Perkin Elmer HTS-7000测定550纳米波长的吸收值。待测样品先用DMSO溶解,再用培养基稀释。DMSO的终浓度小于0.25%。对照组还有相同浓度的DMSO。5-氟尿嘧啶(5-FU) 和 doxorubicin HCl用作阳性对照。EC50值通过取4个孔数据的平均值来计算的。


    (Only for Reference)
动物实验:

[5]

- 合并
  • Animal Models: 接种Lewis肺肿瘤,结肠癌以及黑色素瘤细胞的C57BL/6 和 BALB/c 小鼠
  • Dosages: ~10毫克/千克
  • Administration: 腹腔注射
    (Only for Reference)

溶解度 (25°C)

体外 DMSO 57 mg/mL (200.48 mM)
Water Insoluble
Ethanol '57 mg/mL

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 284.31
化学式

C17H16O4

CAS号 104594-70-9
储存条件 粉状
溶于溶剂
别名 CAPE, Phenylethyl Caffeate

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系Selleck为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % ddH2O
计算重置

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、SDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、SDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

临床试验信息

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04633434 Not yet recruiting Device: The Talk Parenting Skill for Alexa Parenting Practices|Self Efficacy|Stress|Child Behavior|Emotional Adjustment|Sleep Problems|Parent-Child Relations Oregon Research Behavioral Intervention Strategies Inc.|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) September 1 2021 Not Applicable
NCT04028674 Enrolling by invitation Device: Laryngeal Pacing Device Bilateral Vocal Fold Paralysis (BVFP) Vanderbilt University Medical Center|National Institute on Deafness and Other Communication Disorders (NIDCD) January 14 2021 Not Applicable
NCT04633473 Recruiting Behavioral: SIB-Time Web-Application Tool Family Relations|Sibling Relations Oregon Research Behavioral Intervention Strategies Inc. January 1 2021 Not Applicable
NCT03790956 Recruiting Procedure: Silk Microparticle Filler Injection Vocal Cord Paralysis Unilateral|Dysphonia|Dysphagia Oropharyngeal University of Southern California|Sofregen Medical Inc. July 1 2020 Not Applicable
NCT03749863 Enrolling by invitation Procedure: Serial PRP injections Presbylarynx|Atrophy; Larynx|Dysphonia|Vocal Cord Atrophy|Presbylarynges|Vocal Fold Scar|Sulcus Vocalis of Vocal Cord University of Southern California February 18 2020 Not Applicable

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID