Adrenergic Receptor

信号通路图

研究领域

  • 抑制剂选择性比较
  • 溶解性比较
目录号 产品目录 溶解度(25°C)
DMSO 酒精
S1324 Doxazosin Mesylate <1 mg/mL 15 mg/mL <1 mg/mL
S5703 Carvedilol Phosphate -1 mg/mL 100 mg/mL -1 mg/mL
S5723 Carvedilol EP IMpurity E -1 mg/mL 40 mg/mL -1 mg/mL
S5739 Nebivolol -1 mg/mL 88 mg/mL -1 mg/mL
S5088 Labetalone hydrochloride -1 mg/mL 72 mg/mL -1 mg/mL
S4076 Propranolol HCl 6 mg/mL 59 mg/mL <1 mg/mL
S1206 Bisoprolol fumarate 88 mg/mL 88 mg/mL 88 mg/mL
S4113 Desvenlafaxine <1 mg/mL 37 mg/mL 3 mg/mL
S1642 Methyldopa <1 mg/mL 2 mg/mL <1 mg/mL
S4112 Desvenlafaxine Succinate <1 mg/mL 80 mg/mL <1 mg/mL
S2086 Ivabradine HCl 82 mg/mL 101 mg/mL 101 mg/mL
S2113 Cisatracurium Besylate 47 mg/mL 249 mg/mL 249 mg/mL
S1283 Asenapine maleate <1 mg/mL 80 mg/mL <1 mg/mL
S5666 Moxisylyte hydrochloride -1 mg/mL 63 mg/mL -1 mg/mL
S5540 Landiolol hydrochloride 100 mg/mL 100 mg/mL 42 mg/mL
S5341 Metroprolol succinate 100 mg/mL 100 mg/mL 5 mg/mL
S5430 Metoprolol -1 mg/mL 53 mg/mL -1 mg/mL
S5281 Dapiprazole Hydrochloride 72 mg/mL 21 mg/mL 72 mg/mL
S5432 Dibenamine Hydrochloride -1 mg/mL 59 mg/mL -1 mg/mL
S5337 Rauwolscine hydrochloride -1 mg/mL 7 mg/mL -1 mg/mL
S5042 Bevantolol hydrochloride 52 mg/mL 76 mg/mL 61 mg/mL
S4817 Atenolol 35 mg/mL 53 mg/mL 53 mg/mL
S1409 Alfuzosin HCl 85 mg/mL 85 mg/mL 85 mg/mL
S1613 Silodosin <1 mg/mL 99 mg/mL 99 mg/mL
S1549 Nebivolol HCl <1 mg/mL 88 mg/mL <1 mg/mL
S2691 BMY 7378 Dihydrochloride 92 mg/mL 92 mg/mL 20 mg/mL
S1424 Prazosin HCl <1 mg/mL 4 mg/mL <1 mg/mL
S2038 Phentolamine Mesylate 76 mg/mL 76 mg/mL 76 mg/mL
S1856 Metoprolol Tartrate 100 mg/mL 100 mg/mL 31 mg/mL
S2059 Terazosin HCl Dihydrate <1 mg/mL 26 mg/mL <1 mg/mL
S1387 Naftopidil DiHCl <1 mg/mL 41 mg/mL 2 mg/mL
S2517 Maprotiline HCl <1 mg/mL 63 mg/mL 24 mg/mL
S1831 Carvedilol <1 mg/mL 81 mg/mL 4 mg/mL
S2126 Naftopidil <1 mg/mL 79 mg/mL <1 mg/mL
S2499 Phenoxybenzamine HCl 17 mg/mL 68 mg/mL 68 mg/mL
S2509 Sotalol HCl 61 mg/mL 61 mg/mL <1 mg/mL
S4123 Timolol Maleate <1 mg/mL 86 mg/mL 86 mg/mL
S4010 Acebutolol HCl 75 mg/mL 75 mg/mL 75 mg/mL
S1827 Betaxolol HCl 69 mg/mL 69 mg/mL 69 mg/mL
S2607 Buflomedil HCl 69 mg/mL 31 mg/mL 7 mg/mL
S4729 Tamsulosin hydrochloride 17 mg/mL 88 mg/mL 8 mg/mL
S4124 Tolazoline HCl 39 mg/mL 39 mg/mL 39 mg/mL
S4649 Atipamezole hydrochloride 21 mg/mL 12 mg/mL 49 mg/mL
S4650 Atipamezole <1 mg/mL 42 mg/mL 42 mg/mL
S3656 Piribedil <1 mg/mL 59 mg/mL 59 mg/mL
S4679 Terazosin HCl 1 mg/mL 84 mg/mL <1 mg/mL
S4085 Levobetaxolol HCl 69 mg/mL 69 mg/mL 69 mg/mL
S8114 ICI-118551 Hydrochloride 21 mg/mL 62 mg/mL 62 mg/mL
S4100 Esmolol HCl 66 mg/mL 66 mg/mL 66 mg/mL
S2091 Betaxolol 62 mg/mL 62 mg/mL <1 mg/mL
S4278 Carteolol HCl 65 mg/mL 65 mg/mL <1 mg/mL
S2373 Yohimbine HCl <1 mg/mL 12 mg/mL <1 mg/mL
S4291 Labetalol HCl 8 mg/mL 72 mg/mL 7 mg/mL
S2507 Salbutamol Sulfate 68 mg/mL <1 mg/mL <1 mg/mL
S4009 Mirabegron <1 mg/mL 79 mg/mL 8 mg/mL
S2516 Xylazine HCl 12 mg/mL 50 mg/mL 50 mg/mL
S5683 Isoproterenol sulfate dihydrate -1 mg/mL 100 mg/mL -1 mg/mL
S5564 Xylazine -1 mg/mL 44 mg/mL -1 mg/mL
S5727 Tetryzoline 40 mg/mL
S5734 Midodrine hydrochloride 58 mg/mL
S5735 Midodrine 51 mg/mL
S5217 Arformoterol Tartrate -1 mg/mL 99 mg/mL -1 mg/mL
S5654 Indacaterol <1 mg/mL 52 mg/mL 20 mg/mL
S5267 Nylidrin Hydrochloride 67 mg/mL 2 mg/mL
S5537 Tizanidine 15 mg/mL 50 mg/mL 6 mg/mL
S5494 Salbutamol -1 mg/mL 47 mg/mL -1 mg/mL
S5527 Salmeterol <1 mg/mL 83 mg/mL 83 mg/mL
S3960 Higenamine hydrochloride -1 mg/mL 61 mg/mL -1 mg/mL
S3643 Amitraz <1 mg/mL 58 mg/mL <1 mg/mL
S3664 Flupenthixol dihydrochloride 100 mg/mL 100 mg/mL 30 mg/mL
S3083 Indacaterol Maleate <1 mg/mL 102 mg/mL <1 mg/mL
S2566 Isoprenaline HCl 50 mg/mL 50 mg/mL <1 mg/mL
S2020 Formoterol Hemifumarate <1 mg/mL 80 mg/mL <1 mg/mL
S2521 Epinephrine bitartrate 67 mg/mL 67 mg/mL <1 mg/mL
S2458 Clonidine HCl 53 mg/mL 53 mg/mL 53 mg/mL
S3041 Droxidopa <1 mg/mL <1 mg/mL <1 mg/mL
S3075 Dexmedetomidine <1 mg/mL 40 mg/mL 40 mg/mL
S2522 L-Adrenaline <1 mg/mL 4 mg/mL <1 mg/mL
S2569 Phenylephrine HCl 41 mg/mL 41 mg/mL 41 mg/mL
S4065 Guanabenz Acetate <1 mg/mL 58 mg/mL 5 mg/mL
S2519 Naphazoline HCl 49 mg/mL 17 mg/mL 22 mg/mL
S2533 Ritodrine HCl 65 mg/mL 65 mg/mL 65 mg/mL
S2438 Synephrine HCl 41 mg/mL 14 mg/mL 4 mg/mL
S2090 Dexmedetomidine HCl <1 mg/mL 48 mg/mL 48 mg/mL
S3061 Epinephrine HCl 44 mg/mL 44 mg/mL 7 mg/mL
S3060 Medetomidine HCl 47 mg/mL 12 mg/mL 47 mg/mL
S1437 Tizanidine HCl 15 mg/mL 10 mg/mL <1 mg/mL
S2092 Detomidine HCl 45 mg/mL 45 mg/mL 45 mg/mL
S2545 Scopine <1 mg/mL 31 mg/mL <1 mg/mL
S4296 Salmeterol Xinafoate <1 mg/mL 100 mg/mL 4 mg/mL
S2523 DL-Adrenaline <1 mg/mL 0.02 mg/mL <1 mg/mL
S4266 Brimonidine Tartrate 75 mg/mL 88 mg/mL <1 mg/mL
S2615 Noradrenaline bitartrate monohydrate 64 mg/mL 64 mg/mL <1 mg/mL
S7974 L755507 <1 mg/mL 100 mg/mL <1 mg/mL
S4127 Terbutaline Sulfate 100 mg/mL <1 mg/mL <1 mg/mL
S4135 Clorprenaline HCl 50 mg/mL 50 mg/mL 50 mg/mL
S4043 Tetrahydrozoline HCl 47 mg/mL 12 mg/mL 26 mg/mL
S2576 Xylometazoline HCl 56 mg/mL 27 mg/mL 56 mg/mL
S3640 Methoxyphenamine Hydrochloride 43 mg/mL 43 mg/mL 43 mg/mL
S3727 Vilanterol Trifenate <1 mg/mL 100 mg/mL 14 mg/mL
S4693 Guanfacine Hydrochloride 30 mg/mL 56 mg/mL 56 mg/mL
S4277 Bambuterol HCl 72 mg/mL 80 mg/mL 28 mg/mL
S2362 Synephrine <1 mg/mL 33 mg/mL 2 mg/mL
S3185 Adrenalone HCl 44 mg/mL 44 mg/mL <1 mg/mL
S4243 Deoxycorticosterone acetate <1 mg/mL 11 mg/mL 6 mg/mL

特异性亚型抑制剂

产品目录 产品描述 文献引用 实验数据
S1324

Doxazosin Mesylate

Doxazosin Mesylate是一种α-1肾上腺素能受体抑制剂。

S5703New

Carvedilol Phosphate

Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity.

S5723New

Carvedilol EP IMpurity E

Carvedilol is a nonselective beta blocker/alpha-1 blocker and used in management of congestive heart failure (CHF).

S5739New

Nebivolol

Nebivolol is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and also for left ventricular failure.

S5088New

Labetalone hydrochloride

Labetalone hydrochloride是labetalone的盐酸盐形式,labetalone是alpha- 和 beta-adrenergic receptors的阻滞剂,被用作一种降压药。

S4076

Propranolol HCl

Propranolol HCl是一种竞争性和非选择性β-肾上腺素受体抑制剂,IC50为12 nM.

S1206

Bisoprolol fumarate

Bisoprolol fumarate是一种选择性β1型肾上腺素能受体抑制剂。

S4113

Desvenlafaxine

Desvenlafaxine是一种5-羟色胺(5-HT)去甲肾上腺素(NE)重吸收抑制剂,Ki值分别为40.2 nM和558.4 nM。

S1642

Methyldopa

Methyldopa 是DOPA 脱羧酶竞争性抑制剂,ED50为21.8 mg/kg。

S4112

Desvenlafaxine Succinate

Desvenlafaxine Succinate是一种新型5-羟色胺(5-HT)转运蛋白 和去甲肾上腺素(NE)转运蛋白重吸收抑制剂,Ki值分别为40.2 nM和558.4 nM

S2086

Ivabradine HCl

Ivabradine HCl是一种新型If抑制剂,IC50为2.9 μM,特定有效作用于窦房结心脏起搏器活性,是一种纯粹的心跳速率降低剂。

S2113

Cisatracurium Besylate

Cisatracurium Besylate是一种非去极化神经肌肉阻断剂,通过抑制神经肌肉的传导而对乙酰胆碱起拮抗作用。

S1283

Asenapine maleate

Asenapine maleate是一种高亲和性的包括 serotonin, norepinephrine, dopaminehistamine receptors在内的多种受体的拮抗剂,用于治疗神经分裂症以及抑郁狂躁型忧郁症。

S5666New

Moxisylyte hydrochloride

Moxisylyte hydrochloride is an alpha-adrenergic blocking agent used for the treatment of Raynaud's disease.

S9285New

Fargesin

Fargesin is a neolignan isolated from Magnolia plants. It is a potential β1AR antagonist through cAMP/PKA pathway.

S9050New

Boldine

Boldine, isolated from Peumus boldus, has alpha-adrenergic antagonist activities in vascular tissue with anti-oxidant, hepatoprotective, cytoprotective, antipyretic and anti-inflammatory effects.

S5540New

Landiolol hydrochloride

Landiolol hydrochloride is the hydrochloride salt form of Landiolol, which is an ultra-short-acting β1 selective adrenoceptor antagonist.

S5341New

Metroprolol succinate

Metoprolol Succinate is the succinate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity.

S5430New

Metoprolol

Metoprolol is a cardioselective β1-adrenergic blocking agent with log Kd values of −7.26±0.07, −6.89±0.09, −5.16±0.12 for β1, β2, and β3 adrenoceptors, respectively. It is used for acute myocardial infarction, heart failure, angina pectoris and mild to moderate hypertension.

S5281New

Dapiprazole Hydrochloride

Dapiprazole Hydrochloride is the hydrochloride salt form of dapiprazole, an alpha-adrenergic blocker used to reverse mydriasis after eye examination.

S5432New

Dibenamine Hydrochloride

Dibenamine is an irreversible blocker of α1 adrenoceptors.

S5337New

Rauwolscine hydrochloride

Rauwolscine hydrochloride is the hydrochloride salt form of Rauwolscine, a specific and potent α2 antagonist with Ki of 12 nM.

S5042New

Bevantolol hydrochloride

Bevantolol hydrochloride选择性β肾上腺素受体拮抗剂,没有β内源性拟交感活性,膜稳定性较弱,具有局部麻醉作用。

S4817New

Atenolol

Atenolol是一种选择性的β1 receptor拮抗剂,对人源β1-, β2- 和β3-肾上腺受体的log Kd值分别为−6.66±0.05, −5.99±0.14, −4.11±0.07。

S1409

Alfuzosin HCl

Alfuzosin HCl 是一种α1受体拮抗剂,用于治疗良性前列腺增生(BPH)。

S1613

Silodosin

Silodosin是一种α1-肾上腺素受体拮抗剂,具有高泌尿选择性。

S1549

Nebivolol HCl

在兔肺β1-肾上腺素受体结合实验中,Nebivolol HCl选择性阻断β1受体,IC50为0.8 nM。

S2691

BMY 7378 Dihydrochloride

BMY 7378是一种多靶点抑制剂,作用于α2C-adrenoceptorα1D-adrenoceptorpKi分别为6.54和8.2,且为混合型5-HT1A受体激动剂和拮抗剂,pKi为8.3。

S1424

Prazosin HCl

Prazosin HCl是Quinazoline 衍生物,是一种新型的化学类抗高血压药物。

S2038

Phentolamine Mesylate

Phentolamine Mesylate是一种非选择性α-肾上腺素能拮抗剂,IC50为0.1 μM。

S1856

Metoprolol Tartrate

Metoprolol Tartrate是一种心脏选择性的β-肾上腺素能受体抑制剂,IC50为42 ng/mL。

S2059

Terazosin HCl Dihydrate

Terazosin HCl 是α-肾上腺素能受体抑制剂,用于治疗高血压和前列腺肥大。

S1387

Naftopidil DiHCl

Naftopidil DiHCl是一种选择性5-HT1Aα1-adrenergic receptor(α1-肾上腺素受体)拮抗剂,IC50分别为0.1 μM和0.2 μM。

S2517

Maprotiline HCl

Maprotiline HCl是一种选择性去甲肾上腺素再摄取抑制剂,也是一种四环类抗抑郁药。

S1831

Carvedilol

Carvedilol是一种非选择性β/α-1受体抑制剂,用于治疗充血性心力衰竭和高血压。

S2126

Naftopidil

Naftopidil 是选择性α1-肾上腺素能受体拮抗剂,或α受体抑制剂,Ki为58.3 nM。

S2499

Phenoxybenzamine HCl

Phenoxybenzamine HCl是一种非选择性,不可逆α受体拮抗剂,IC50为550 nM。

S2509

Sotalol HCl

Sotalol 是一种非选择性β受体抑制剂,是钾离子通道抑制剂,IC50为43 μM。

S4123

Timolol Maleate

Timolol Maleate是一种非选择性的β-肾上腺素能受体拮抗剂,作用于β1/β2Ki为1.97 nM/2.0 nM。

S4010

Acebutolol HCl

Acebutolol HCl是beta-adrenergic receptors(β-肾上腺素能受体)拮抗剂,用于治疗高血压,心绞痛,和心律失常。

S1827

Betaxolol HCl

Betaxolol HCl是一种β1肾上腺素受体阻断剂,IC50是6 Μm。

S2607

Buflomedil HCl

Buflomedil HCl是一种血管扩张剂,用于治疗跛行或外周动脉疾病的症状。是一种非选择性alpha adrenergic receptor抑制剂。

S4729

Tamsulosin hydrochloride

Tamsulosin是有效的、选择性α1a肾上腺素能受体拮抗剂,对α1a-AR, α1b-AR 和α1d-AR的Ki值分别为0.13 nM, 1.92 nM 和 0.18 nM。

S4124

Tolazoline HCl

Tolazoline HCl是一种非选择性和竞争性的α-肾上腺素能受体拮抗剂。

S4649

Atipamezole hydrochloride

Atipamezole是一种合成的α2肾上腺素能受体拮抗剂。作为潜在抗帕金森病的药物在人类中被研究。Atipamezole hydrochloride是atipamezole的盐酸盐形式。

S4650

Atipamezole

Atipamezole是一种合成的α2肾上腺素能受体拮抗剂。作为潜在抗帕金森病的药物在人类中被研究。

S3656

Piribedil

Piribedil is a relatively selective dopamine (D2/D3) agonist with moderate antidepressant activity. It also has α2-adrenergic (α2A/α2C) antagonist properties.

S4679

Terazosin HCl

Terazosin是一种选择性的alpha-1拮抗剂,用于治疗前列腺肿大症状。它通过抑制膀胱平滑肌和血管壁上的肾上腺素的作用发挥效应。

S4085

Levobetaxolol HCl

Levobetaxolol高亲和力作用于克隆的人β1和β2受体,Ki分别为0.76 nM和32.6 nM。

S8114

ICI-118551 Hydrochloride

ICI-118551是高选择性的β2肾上腺素受体拮抗剂,其对β2,β1和β3 受体的Ki值分别为0.7, 49.5和611 nM。

S4100

Esmolol HCl

Esmolol是一种心脏选择性B受体阻滞剂,用于控制心跳急或异常心率节律。

S2091

Betaxolol

Betaxolol是一种选择性的β1肾上腺素能受体抑制剂,用于治疗高血压和青光眼。

S4278

Carteolol HCl

Carteolol HCl 是一种β-adrenoceptor拮抗剂,用于治疗青光眼。

S2373

Yohimbine HCl

Yohimbine HCl 是一种瞳孔放大剂,用于治疗阳痿,也是一种春药。

S4291

Labetalol HCl

Labetalol HCl是一种选择性alpha1-adrenergic 和非选择性beta-adrenergic receptors的双重拮抗剂,用于高血压的治疗。

S2507

Salbutamol Sulfate

Salbutamol Sulfate是一种短效的β2-肾上腺素能受体激动剂,IC50为8.93 µM。

S4009

Mirabegron

Mirabegron是一种选择性的beta3-adrenoceptor(β3肾上腺素受体)激动剂,EC50为22.4 nM。

S2516

Xylazine HCl

Xylazine HCl是一种α2肾上腺素能受体激动剂,用作镇定剂和肌肉松弛剂。

S5683New

Isoproterenol sulfate dihydrate

Isoproterenol Sulfate is the sulfate salt form of isoproterenol, a beta-adrenergic receptor agonist with bronchodilator activity.

S5750New

DL-Norepinephrine hydrochloride

Norepinephrine is the neurotransmitter at most sympathetic neuroeffector junctions and has pharmacologic effects on both α1 and β1 adrenoceptors.

S5751New

Dihydroergotamine Mesylate

Dihydroergotamine Mesylate is an ergot derivative with agonistic activity for alpha-adrenergic, serotonergic, and dopaminergic receptors.

S9507New

(−)-Norepinephrine

(−)-Norepinephrine是一种天然存在的神经递质和激素。它是adrenergic receptors的激动剂,对α1, α2A和β1肾上腺素受体的Ki值分别为330 nM、56 nM和740 nM。

S9508New

Brimonidine

Brimonidine is an alpha adrenergic receptor agonist (primarily alpha-2) and is used for the treatment of open-angle glaucoma or ocular hypertension to lower intraocular pressure.

S5564New

Xylazine

Xylazine is a partial alpha-2 adrenergic agonist that is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals.

S5727New

Tetryzoline

Tetryzoline is an alpha-adrenergic agonist used in some over-the-counter eye drops and nasal sprays.

S5734New

Midodrine hydrochloride

Midodrine hydrochloride is the hydrochloride salt form of midodrine, an adrenergic alpha-1 agonist used as a vasopressor.

S5735New

Midodrine

Midodrine belongs to the class of medications known as vasopressors. It is an adrenergic alpha-1 agonist.

S5217New

Arformoterol Tartrate

Arformoterol Tartrate is the tartrate salt of arformoterol, a long-acting beta-2 adrenergic agonist with bronchodilator activity.

S5654New

Indacaterol

Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor.

S5267New

Nylidrin Hydrochloride

Nylidrin Hydrochloride, a β-adrenergic agonist, is used therapeutically for its vasodilating effect on the peripheral circulation and possibly on the cerebral circulation as well.

S5537New

Tizanidine

S5494New

Salbutamol

Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases.

S5527New

Salmeterol

Salmeterol is a long-acting beta2-adrenergic receptor agonist with Ki value of 1.5 nM for WT β2AR and shows very high selectivity for the WT β2AR(β1Ki/β2Ki ratio of approximately 1500).

S3960New

Higenamine hydrochloride

Higenamine, also known as Norcoclaurine HCl, is a non-selective β2 adrenoceptor agonist which is a chemical compound naturally occurring in a number of plants.

S3643New

Amitraz

Amitraz是一种α2 肾上腺素能受体激动剂。它是非系统性杀螨剂和杀虫剂。

S3664New

Flupenthixol dihydrochloride

Flupentixol是一种抗精神病安定药物,是D1 and D2多巴胺受体的强效拮抗剂,也是α肾上腺素能受体的拮抗剂。

S3083

Indacaterol Maleate

Indacaterol Maleate是一种超长效的β-adrenoceptor激动剂,对β1-adrenoceptor的pKi为 7.36,对 β2-adrenoceptor 的pKi为5.48。

S2566

Isoprenaline HCl

Isoprenaline是一种非选择性β-肾上腺素能受体激动剂,用于治疗心动过缓和心传导阻滞。

S2020

Formoterol Hemifumarate

Formoterol Hemifumarate是一种有效的,选择性的,长效β2-adrenoceptor 激动剂,用于治疗哮喘以及慢性阻塞性肺病。

S2521

Epinephrine bitartrate

Epinephrine Bitartrate 是一种α和β-肾上腺素能受体激动剂。

S2458

Clonidine HCl

Clonidine HCl 是一种直接起作用的α2肾上腺素能受体激动剂,ED50为0.02±0.01 mg/kg。

S3041

Droxidopa

Droxidopa是一种精神药物,是合成的氨基酸前体,它作为神经传导物质去甲肾上腺素和肾上腺素的前药来发挥作用。

S3075

Dexmedetomidine

Dexmedetomidine是特护病房和麻醉师使用的一种镇静剂。

S2522

L-Adrenaline

L-Adrenaline属于儿茶酚胺类。

S2569

Phenylephrine HCl

Phenylephrine HCl是一种选择性的α1-肾上腺素能受体激动剂。

S4065

Guanabenz Acetate

Guanabenz Acetate是一种选择性的α2a-肾上腺素能受体α2b-肾上腺素能受体α2c-肾上腺素能受体激动剂,pEC50分别为8.25, 7.01和5左右。

S2519

Naphazoline HCl

Naphazoline HCl 是一种眼部血管收缩剂,是咪唑啉衍生的拟交感胺类。

S2533

Ritodrine HCl

Ritodrine HCl 是Ritodrine的盐酸盐,是β-2肾上腺素能受体激动剂。

S2438

Synephrine HCl

Synephrine HCl是一种交感神经α-adrenergic receptor (AR)(肾上腺素受体)激动剂。

S2090

Dexmedetomidine HCl

Dexmedetomidine HCl 是一种有效的,高度选择性α-2肾上腺素受体激动剂,具有显著的镇静效果,从而降低患者的麻醉量。

S3061

Epinephrine HCl

Epinephrine HCl是一种激素和神经递质。

S3060

Medetomidine HCl

Medetomidine HCl是一种选择性的α2-adrenoceptor(α2-肾上腺素受体)激动剂,Ki为1.08 nM,比作用于α1-adrenoceptor选择性高1620倍。

S1437

Tizanidine HCl

Tizanidine HCl是一种α2-肾上腺素受体,抑制中枢神经系统去甲肾上腺素能神经的神经递质的释放。

S2092

Detomidine HCl

Detomidine HCl可产生镇静和镇痛作用,这种作用具有剂量依赖性,通过激活α2儿茶酚胺受体来调节。

S2545

Scopine

Scopine是Anisodine的代谢产物,是一种α1-肾上腺素能受体激动剂,用于治疗急性循环性休克。

S4296

Salmeterol Xinafoate

Salmeterol Xinafoate是一种长效的β2-adrenergic receptor激动剂,具有抗炎作用,用于哮喘症状和慢性阻塞性肺疾病(COPD)症状的治疗。

S2523

DL-Adrenaline

DL-Adrenaline是一种激素,是由肾上腺髓质分泌的一种神经递质。

S4266

Brimonidine Tartrate

Brimonidine Tartrate是一种高选择性的α-肾上腺素能受体激动剂,EC50为0.45 nM,用于治疗开角型青光眼或高眼压症。

S2615

Noradrenaline bitartrate monohydrate

Noradrenaline bitartrate monohydrate 是一种直接的α-肾上腺素能受体激动剂。

S7974

L755507

L-755,507是一种有效的、选择性的β3肾上腺素能受体部分激动剂,EC50为0.43 nM。它能在iPSCs和其他细胞类型中增强CRISPR介导的同源重组修复效率。

S4127

Terbutaline Sulfate

Terbutaline Sulfate是一种选择性的β2-肾上腺素能受体激动剂,IC50为53 nM。

S4135

Clorprenaline HCl

Clorprenaline HCl是β2-受体激动剂,具有显著的扩张支气管作用。

S4043

Tetrahydrozoline HCl

Tetrahydrozoline HCl是一种咪唑啉衍生物,具有α受体激动剂活性。

S2576

Xylometazoline HCl

Xylometazoline HCl 是α-adrenoceptor激动剂,常用作鼻血管收缩药,高效作用于α2B肾上腺素受体亚型,EC50为4 μM。

S3640

Methoxyphenamine Hydrochloride

Methoxyphenamine Hydrochloride is a β-adrenergic receptor agonist of the amphetamine class used as a bronchodilator.

S3727

Vilanterol Trifenate

Vilanterol trifenatate is a novel inhaled long-acting beta2 adrenoceptor agonist with inherent 24-hour activity for once daily treatment of COPD and asthma.

S4693

Guanfacine Hydrochloride

Guanfacine Hydrochloride是一种选择性的α2A-肾上腺素受体激动剂,具有降压效果。

S4277

Bambuterol HCl

Bambuterol HCl是强效β-adrenoceptor拮抗剂,用于治疗哮喘。

S2362

Synephrine

Synephrine是从苦橘及其他柑橘属植物中提取的一种不饱和的植物甾醇,常用于减肥。

S3185

Adrenalone HCl

Adrenalone HCl是一种肾上腺素激动剂,作为外用的血管收缩剂和止血剂,主要作用于α-1肾上腺素受体。

S4243

Deoxycorticosterone acetate

Deoxycorticosterone acetate是一种类固醇激素,用于肌肉注射,是肾上腺皮质类固醇的代替疗法。

Tags: adrenergic receptor activation | adrenergic receptor types | adrenergic receptor location | adrenergic receptor drugs | adrenergic receptor signaling | adrenergic receptor pathway | beta adrenergic receptor pathway | beta adrenergic receptor activation | beta 2 adrenergic receptor activation | beta 2 adrenergic receptor pathway | alpha adrenergic receptor pathway | alpha 1 adrenergic receptor pathway | beta 1 adrenergic receptor pathway | adrenergic receptor inhibitor review