Adrenergic Receptor
信号通路图
研究领域
- 抑制剂选择性比较
- 溶解性比较
| 目录号 | 产品目录 | 溶解度(25°C) | ||
|---|---|---|---|---|
| 水 | DMSO | 酒精 | ||
| S1324 | Doxazosin Mesylate | <1 mg/mL | 15 mg/mL | <1 mg/mL |
| S5088 | Labetalone hydrochloride | -1 mg/mL | 72 mg/mL | -1 mg/mL |
| S4076 | Propranolol HCl | 6 mg/mL | 59 mg/mL | <1 mg/mL |
| S1206 | Bisoprolol fumarate | 88 mg/mL | 88 mg/mL | 88 mg/mL |
| S4113 | Desvenlafaxine | <1 mg/mL | 37 mg/mL | 3 mg/mL |
| S1642 | Methyldopa | <1 mg/mL | 2 mg/mL | <1 mg/mL |
| S4112 | Desvenlafaxine Succinate | <1 mg/mL | 80 mg/mL | <1 mg/mL |
| S2086 | Ivabradine HCl | 82 mg/mL | 101 mg/mL | 101 mg/mL |
| S2113 | Cisatracurium Besylate | 47 mg/mL | 249 mg/mL | 249 mg/mL |
| S1283 | Asenapine maleate | <1 mg/mL | 80 mg/mL | <1 mg/mL |
| S5540 | Landiolol hydrochloride | 100 mg/mL | 100 mg/mL | 42 mg/mL |
| S5341 | Metroprolol succinate | 100 mg/mL | 100 mg/mL | 5 mg/mL |
| S5430 | Metoprolol | -1 mg/mL | 53 mg/mL | -1 mg/mL |
| S5281 | Dapiprazole Hydrochloride | 72 mg/mL | 21 mg/mL | 72 mg/mL |
| S5432 | Dibenamine Hydrochloride | -1 mg/mL | 59 mg/mL | -1 mg/mL |
| S5337 | Rauwolscine hydrochloride | -1 mg/mL | 7 mg/mL | -1 mg/mL |
| S5042 | Bevantolol hydrochloride | 52 mg/mL | 76 mg/mL | 61 mg/mL |
| S4817 | Atenolol | 35 mg/mL | 53 mg/mL | 53 mg/mL |
| S1409 | Alfuzosin HCl | 85 mg/mL | 85 mg/mL | 85 mg/mL |
| S1613 | Silodosin | <1 mg/mL | 99 mg/mL | 99 mg/mL |
| S1549 | Nebivolol HCl | <1 mg/mL | 88 mg/mL | <1 mg/mL |
| S2691 | BMY 7378 Dihydrochloride | 92 mg/mL | 92 mg/mL | 20 mg/mL |
| S1424 | Prazosin HCl | <1 mg/mL | 4 mg/mL | <1 mg/mL |
| S2038 | Phentolamine Mesylate | 76 mg/mL | 76 mg/mL | 76 mg/mL |
| S1856 | Metoprolol Tartrate | 100 mg/mL | 100 mg/mL | 31 mg/mL |
| S2059 | Terazosin HCl Dihydrate | <1 mg/mL | 26 mg/mL | <1 mg/mL |
| S1387 | Naftopidil DiHCl | <1 mg/mL | 41 mg/mL | 2 mg/mL |
| S2517 | Maprotiline HCl | <1 mg/mL | 63 mg/mL | 24 mg/mL |
| S1831 | Carvedilol | <1 mg/mL | 81 mg/mL | 4 mg/mL |
| S2126 | Naftopidil | <1 mg/mL | 79 mg/mL | <1 mg/mL |
| S2499 | Phenoxybenzamine HCl | 17 mg/mL | 68 mg/mL | 68 mg/mL |
| S2509 | Sotalol HCl | 61 mg/mL | 61 mg/mL | <1 mg/mL |
| S4123 | Timolol Maleate | <1 mg/mL | 86 mg/mL | 86 mg/mL |
| S4010 | Acebutolol HCl | 75 mg/mL | 75 mg/mL | 75 mg/mL |
| S1827 | Betaxolol HCl | 69 mg/mL | 69 mg/mL | 69 mg/mL |
| S2607 | Buflomedil HCl | 69 mg/mL | 31 mg/mL | 7 mg/mL |
| S4729 | Tamsulosin hydrochloride | 17 mg/mL | 88 mg/mL | 8 mg/mL |
| S4124 | Tolazoline HCl | 39 mg/mL | 39 mg/mL | 39 mg/mL |
| S4649 | Atipamezole hydrochloride | 21 mg/mL | 12 mg/mL | 49 mg/mL |
| S4650 | Atipamezole | <1 mg/mL | 42 mg/mL | 42 mg/mL |
| S4679 | Terazosin HCl | 1 mg/mL | 84 mg/mL | <1 mg/mL |
| S4085 | Levobetaxolol HCl | 69 mg/mL | 69 mg/mL | 69 mg/mL |
| S8114 | ICI-118551 Hydrochloride | 21 mg/mL | 62 mg/mL | 62 mg/mL |
| S4100 | Esmolol HCl | 66 mg/mL | 66 mg/mL | 66 mg/mL |
| S2091 | Betaxolol | 62 mg/mL | 62 mg/mL | <1 mg/mL |
| S4278 | Carteolol HCl | 65 mg/mL | 65 mg/mL | <1 mg/mL |
| S2373 | Yohimbine HCl | <1 mg/mL | 12 mg/mL | <1 mg/mL |
| S4291 | Labetalol HCl | 8 mg/mL | 72 mg/mL | 7 mg/mL |
| S2507 | Salbutamol Sulfate | 68 mg/mL | <1 mg/mL | <1 mg/mL |
| S4009 | Mirabegron | <1 mg/mL | 79 mg/mL | 8 mg/mL |
| S2516 | Xylazine HCl | 12 mg/mL | 50 mg/mL | 50 mg/mL |
| S5217 | Arformoterol Tartrate | -1 mg/mL | 99 mg/mL | -1 mg/mL |
| S5654 | Indacaterol | <1 mg/mL | 52 mg/mL | 20 mg/mL |
| S5267 | Nylidrin Hydrochloride | 67 mg/mL | 2 mg/mL | |
| S5537 | Tizanidine | 15 mg/mL | 50 mg/mL | 6 mg/mL |
| S5494 | Salbutamol | -1 mg/mL | 47 mg/mL | -1 mg/mL |
| S5527 | Salmeterol | <1 mg/mL | 83 mg/mL | 83 mg/mL |
| S3960 | Higenamine hydrochloride | -1 mg/mL | 61 mg/mL | -1 mg/mL |
| S3643 | Amitraz | <1 mg/mL | 58 mg/mL | <1 mg/mL |
| S3664 | Flupenthixol dihydrochloride | 100 mg/mL | 100 mg/mL | 30 mg/mL |
| S3640 | Methoxyphenamine Hydrochloride | 43 mg/mL | 43 mg/mL | 43 mg/mL |
| S3727 | Vilanterol Trifenate | <1 mg/mL | 100 mg/mL | 14 mg/mL |
| S3656 | Piribedil | <1 mg/mL | 59 mg/mL | 59 mg/mL |
| S3083 | Indacaterol Maleate | <1 mg/mL | 102 mg/mL | <1 mg/mL |
| S2566 | Isoprenaline HCl | 50 mg/mL | 50 mg/mL | <1 mg/mL |
| S2020 | Formoterol Hemifumarate | <1 mg/mL | 80 mg/mL | <1 mg/mL |
| S2521 | Epinephrine bitartrate | 67 mg/mL | 67 mg/mL | <1 mg/mL |
| S2458 | Clonidine HCl | 53 mg/mL | 53 mg/mL | 53 mg/mL |
| S3041 | Droxidopa | <1 mg/mL | <1 mg/mL | <1 mg/mL |
| S3075 | Dexmedetomidine | <1 mg/mL | 40 mg/mL | 40 mg/mL |
| S2522 | L-Adrenaline | <1 mg/mL | 4 mg/mL | <1 mg/mL |
| S2569 | Phenylephrine HCl | 41 mg/mL | 41 mg/mL | 41 mg/mL |
| S4065 | Guanabenz Acetate | <1 mg/mL | 58 mg/mL | 5 mg/mL |
| S2519 | Naphazoline HCl | 49 mg/mL | 17 mg/mL | 22 mg/mL |
| S2533 | Ritodrine HCl | 65 mg/mL | 65 mg/mL | 65 mg/mL |
| S2438 | Synephrine HCl | 41 mg/mL | 14 mg/mL | 4 mg/mL |
| S2090 | Dexmedetomidine HCl | <1 mg/mL | 48 mg/mL | 48 mg/mL |
| S3061 | Epinephrine HCl | 44 mg/mL | 44 mg/mL | 7 mg/mL |
| S3060 | Medetomidine HCl | 47 mg/mL | 12 mg/mL | 47 mg/mL |
| S1437 | Tizanidine HCl | 15 mg/mL | 10 mg/mL | <1 mg/mL |
| S2092 | Detomidine HCl | 45 mg/mL | 45 mg/mL | 45 mg/mL |
| S2545 | Scopine | <1 mg/mL | 31 mg/mL | <1 mg/mL |
| S4296 | Salmeterol Xinafoate | <1 mg/mL | 100 mg/mL | 4 mg/mL |
| S2523 | DL-Adrenaline | <1 mg/mL | 0.02 mg/mL | <1 mg/mL |
| S4266 | Brimonidine Tartrate | 75 mg/mL | 88 mg/mL | <1 mg/mL |
| S2615 | Noradrenaline bitartrate monohydrate | 64 mg/mL | 64 mg/mL | <1 mg/mL |
| S7974 | L755507 | <1 mg/mL | 100 mg/mL | <1 mg/mL |
| S4127 | Terbutaline Sulfate | 100 mg/mL | <1 mg/mL | <1 mg/mL |
| S4135 | Clorprenaline HCl | 50 mg/mL | 50 mg/mL | 50 mg/mL |
| S4043 | Tetrahydrozoline HCl | 47 mg/mL | 12 mg/mL | 26 mg/mL |
| S2576 | Xylometazoline HCl | 56 mg/mL | 27 mg/mL | 56 mg/mL |
| S4693 | Guanfacine Hydrochloride | 30 mg/mL | 56 mg/mL | 56 mg/mL |
| S4277 | Bambuterol HCl | 72 mg/mL | 80 mg/mL | 28 mg/mL |
| S2362 | Synephrine | <1 mg/mL | 33 mg/mL | 2 mg/mL |
| S3185 | Adrenalone HCl | 44 mg/mL | 44 mg/mL | <1 mg/mL |
| S4243 | Deoxycorticosterone acetate | <1 mg/mL | 11 mg/mL | 6 mg/mL |
- Adrenergic Receptor抑制剂（96）
- 新Adrenergic Receptor产品
| 产品目录 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|
| S1324 |
Doxazosin MesylateDoxazosin Mesylate是一种α-1肾上腺素能受体抑制剂。 |
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| S5088New |
Labetalone hydrochlorideLabetalone hydrochloride是labetalone的盐酸盐形式，labetalone是alpha- 和 beta-adrenergic receptors的阻滞剂，被用作一种降压药。 |
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| S4076 |
Propranolol HClPropranolol HCl是一种竞争性和非选择性β-肾上腺素受体抑制剂，IC50为12 nM. |
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| S1206 |
Bisoprolol fumarateBisoprolol fumarate是一种选择性β1型肾上腺素能受体抑制剂。 |
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| S4113 |
DesvenlafaxineDesvenlafaxine是一种5-羟色胺(5-HT)和去甲肾上腺素(NE)重吸收抑制剂，Ki值分别为40.2 nM和558.4 nM。 |
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| S1642 |
MethyldopaMethyldopa 是DOPA 脱羧酶竞争性抑制剂，ED50为21.8 mg/kg。 |
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| S4112 |
Desvenlafaxine SuccinateDesvenlafaxine Succinate是一种新型5-羟色胺(5-HT)转运蛋白 和去甲肾上腺素(NE)转运蛋白重吸收抑制剂，Ki值分别为40.2 nM和558.4 nM |
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| S2086 |
Ivabradine HClIvabradine HCl是一种新型If抑制剂，IC50为2.9 μM，特定有效作用于窦房结心脏起搏器活性，是一种纯粹的心跳速率降低剂。 |
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| S2113 |
Cisatracurium BesylateCisatracurium Besylate是一种非去极化神经肌肉阻断剂，通过抑制神经肌肉的传导而对乙酰胆碱起拮抗作用。 |
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| S1283 |
Asenapine maleateAsenapine maleate是一种高亲和性的包括 serotonin, norepinephrine, dopamine 和 histamine receptors在内的多种受体的拮抗剂，用于治疗神经分裂症以及抑郁狂躁型忧郁症。 |
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| S5540New |
Landiolol hydrochlorideLandiolol hydrochloride is the hydrochloride salt form of Landiolol, which is an ultra-short-acting β1 selective adrenoceptor antagonist. |
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| S5341New |
Metroprolol succinateMetoprolol Succinate is the succinate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. |
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| S5430New |
MetoprololMetoprolol is a cardioselective β1-adrenergic blocking agent with log Kd values of −7.26±0.07, −6.89±0.09, −5.16±0.12 for β1, β2, and β3 adrenoceptors, respectively. It is used for acute myocardial infarction, heart failure, angina pectoris and mild to moderate hypertension. |
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| S5281New |
Dapiprazole HydrochlorideDapiprazole Hydrochloride is the hydrochloride salt form of dapiprazole, an alpha-adrenergic blocker used to reverse mydriasis after eye examination. |
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| S5432New |
Dibenamine HydrochlorideDibenamine is an irreversible blocker of α1 adrenoceptors. |
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| S5337New |
Rauwolscine hydrochlorideRauwolscine hydrochloride is the hydrochloride salt form of Rauwolscine, a specific and potent α2 antagonist with Ki of 12 nM. |
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| S5042New |
Bevantolol hydrochlorideBevantolol hydrochloride选择性β肾上腺素受体拮抗剂，没有β内源性拟交感活性，膜稳定性较弱，具有局部麻醉作用。 |
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| S4817New |
AtenololAtenolol是一种选择性的β1 receptor拮抗剂，对人源β1-, β2- 和β3-肾上腺受体的log Kd值分别为−6.66±0.05, −5.99±0.14, −4.11±0.07。 |
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| S1409 |
Alfuzosin HClAlfuzosin HCl 是一种α1受体拮抗剂，用于治疗良性前列腺增生（BPH）。 |
PC-3 and LNCaP cell viability following treatment with a1-adrenoceptor antagonists. (A) Cells were treated with drug (0.01-100 μM) for 72 hr and cell viability determined using the resazurin reduction assay. (B) Effect of treatment duration on PC-3 and LNCap cell survival following treatment with doxazosin (30 μM) or prazosin (30 μM). Survival is expressed as the percentage values of untreated vehicle control and values are the mean ( sem) of six independent determinations each conducted in triplicate. *P<0.05, ***P<0.001 compared to corresponding values for LNCap cells.
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| S1613 |
SilodosinSilodosin是一种α1-肾上腺素受体拮抗剂，具有高泌尿选择性。 |
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| S1549 |
Nebivolol HCl在兔肺β1-肾上腺素受体结合实验中，Nebivolol HCl选择性阻断β1受体，IC50为0.8 nM。 |
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| S2691 |
BMY 7378 DihydrochlorideBMY 7378是一种多靶点抑制剂，作用于α2C-adrenoceptor和α1D-adrenoceptor，pKi分别为6.54和8.2，且为混合型5-HT1A受体激动剂和拮抗剂，pKi为8.3。 |
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| S1424 |
Prazosin HClPrazosin HCl是Quinazoline 衍生物，是一种新型的化学类抗高血压药物。 |
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| S2038 |
Phentolamine MesylatePhentolamine Mesylate是一种非选择性α-肾上腺素能拮抗剂，IC50为0.1 μM。 |
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| S1856 |
Metoprolol TartrateMetoprolol Tartrate是一种心脏选择性的β-肾上腺素能受体抑制剂，IC50为42 ng/mL。 |
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| S2059 |
Terazosin HCl DihydrateTerazosin HCl 是α-肾上腺素能受体抑制剂，用于治疗高血压和前列腺肥大。 |
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| S1387 |
Naftopidil DiHClNaftopidil DiHCl是一种选择性5-HT1A和α1-adrenergic receptor（α1-肾上腺素受体）拮抗剂，IC50分别为0.1 μM和0.2 μM。 |
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| S2517 |
Maprotiline HClMaprotiline HCl是一种选择性去甲肾上腺素再摄取抑制剂，也是一种四环类抗抑郁药。 |
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| S1831 |
CarvedilolCarvedilol是一种非选择性β/α-1受体抑制剂，用于治疗充血性心力衰竭和高血压。 |
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| S2126 |
NaftopidilNaftopidil 是选择性α1-肾上腺素能受体拮抗剂，或α受体抑制剂，Ki为58.3 nM。 |
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| S2499 |
Phenoxybenzamine HClPhenoxybenzamine HCl是一种非选择性，不可逆α受体拮抗剂，IC50为550 nM。 |
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| S2509 |
Sotalol HClSotalol 是一种非选择性β受体抑制剂，是钾离子通道抑制剂，IC50为43 μM。 |
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| S4123 |
Timolol MaleateTimolol Maleate是一种非选择性的β-肾上腺素能受体拮抗剂，作用于β1/β2，Ki为1.97 nM/2.0 nM。 |
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| S4010 |
Acebutolol HClAcebutolol HCl是beta-adrenergic receptors（β-肾上腺素能受体）拮抗剂，用于治疗高血压，心绞痛，和心律失常。 |
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| S1827 |
Betaxolol HClBetaxolol HCl是一种β1肾上腺素受体阻断剂，IC50是6 Μm。 |
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| S2607 |
Buflomedil HClBuflomedil HCl是一种血管扩张剂，用于治疗跛行或外周动脉疾病的症状。是一种非选择性alpha adrenergic receptor抑制剂。 |
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| S4729 |
Tamsulosin hydrochlorideTamsulosin是有效的、选择性α1a肾上腺素能受体拮抗剂，对α1a-AR, α1b-AR 和α1d-AR的Ki值分别为0.13 nM, 1.92 nM 和 0.18 nM。 |
The presence of autophagosomes was visualized by fluorescent microscopy. (Cytotoxicity, caspase-3 activity and autophagy induced by treatment of PC-3 and LNCap cells with prazosin or doxazosin for 24 hr)
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| S4124 |
Tolazoline HClTolazoline HCl是一种非选择性和竞争性的α-肾上腺素能受体拮抗剂。 |
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| S4649 |
Atipamezole hydrochlorideAtipamezole是一种合成的α2肾上腺素能受体拮抗剂。作为潜在抗帕金森病的药物在人类中被研究。Atipamezole hydrochloride是atipamezole的盐酸盐形式。 |
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| S4650 |
AtipamezoleAtipamezole是一种合成的α2肾上腺素能受体拮抗剂。作为潜在抗帕金森病的药物在人类中被研究。 |
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| S4679 |
Terazosin HClTerazosin是一种选择性的alpha-1拮抗剂，用于治疗前列腺肿大症状。它通过抑制膀胱平滑肌和血管壁上的肾上腺素的作用发挥效应。 |
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| S4085 |
Levobetaxolol HClLevobetaxolol高亲和力作用于克隆的人β1和β2受体，Ki分别为0.76 nM和32.6 nM。 |
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| S8114 |
ICI-118551 HydrochlorideICI-118551是高选择性的β2肾上腺素受体拮抗剂，其对β2,β1和β3 受体的Ki值分别为0.7, 49.5和611 nM。 |
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| S4100 |
Esmolol HClEsmolol是一种心脏选择性B受体阻滞剂，用于控制心跳急或异常心率节律。 |
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| S2091 |
BetaxololBetaxolol是一种选择性的β1肾上腺素能受体抑制剂，用于治疗高血压和青光眼。 |
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| S4278 |
Carteolol HClCarteolol HCl 是一种β-adrenoceptor拮抗剂,用于治疗青光眼。 |
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| S2373 |
Yohimbine HClYohimbine HCl 是一种瞳孔放大剂，用于治疗阳痿，也是一种春药。 |
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| S4291 |
Labetalol HClLabetalol HCl是一种选择性alpha1-adrenergic 和非选择性beta-adrenergic receptors的双重拮抗剂，用于高血压的治疗。 |
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| S2507 |
Salbutamol SulfateSalbutamol Sulfate是一种短效的β2-肾上腺素能受体激动剂，IC50为8.93 µM。 |
(B) Bar graphs summarize the incidence of VA from Con (An external file that holds a picture, illustration, etc. Object name is srep07681-m1.jpg) and HF (An external file that holds a picture, illustration, etc. Object name is srep07681-m2.jpg) guinea pigs before and after administration of Sal (10 μM) or Sal plus ICI (1 μM) (*p < 0.05, HF + Sal vs. Con + Sal; #p < 0.05, HF + Sal vs. HF + Sal + ICI, n = 6).
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| S4009 |
MirabegronMirabegron是一种选择性的beta3-adrenoceptor（β3肾上腺素受体）激动剂，EC50为22.4 nM。 |
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| S2516 |
Xylazine HClXylazine HCl是一种α2肾上腺素能受体激动剂，用作镇定剂和肌肉松弛剂。 |
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| S5217New |
Arformoterol TartrateArformoterol Tartrate is the tartrate salt of arformoterol, a long-acting beta-2 adrenergic agonist with bronchodilator activity. |
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| S5654New |
IndacaterolIndacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor. |
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| S5267New |
Nylidrin HydrochlorideNylidrin Hydrochloride, a β-adrenergic agonist, is used therapeutically for its vasodilating effect on the peripheral circulation and possibly on the cerebral circulation as well. |
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| S5537New |
Tizanidine |
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| S5494New |
SalbutamolSalbutamol is a short-acting, selective beta2-adrenergic receptor agonist used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases. |
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| S5527New |
SalmeterolSalmeterol is a long-acting beta2-adrenergic receptor agonist with Ki value of 1.5 nM for WT β2AR and shows very high selectivity for the WT β2AR(β1Ki/β2Ki ratio of approximately 1500). |
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| S3960New |
Higenamine hydrochlorideHigenamine, also known as Norcoclaurine HCl, is a non-selective β2 adrenoceptor agonist which is a chemical compound naturally occurring in a number of plants. |
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| S3643New |
AmitrazAmitraz是一种α2 肾上腺素能受体激动剂。它是非系统性杀螨剂和杀虫剂。 |
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| S3664New |
Flupenthixol dihydrochlorideFlupentixol是一种抗精神病安定药物，是D1 and D2多巴胺受体的强效拮抗剂，也是α肾上腺素能受体的拮抗剂。 |
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| S3640New |
Methoxyphenamine HydrochlorideMethoxyphenamine Hydrochloride is a β-adrenergic receptor agonist of the amphetamine class used as a bronchodilator. |
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| S3727New |
Vilanterol TrifenateVilanterol trifenatate is a novel inhaled long-acting beta2 adrenoceptor agonist with inherent 24-hour activity for once daily treatment of COPD and asthma. |
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| S3656New |
PiribedilPiribedil is a relatively selective dopamine (D2/D3) agonist with moderate antidepressant activity. It also has α2-adrenergic (α2A/α2C) antagonist properties. |
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| S3083 |
Indacaterol MaleateIndacaterol Maleate是一种超长效的β-adrenoceptor激动剂，对β1-adrenoceptor的pKi为 7.36，对 β2-adrenoceptor 的pKi为5.48。 |
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| S2566 |
Isoprenaline HClIsoprenaline是一种非选择性β-肾上腺素能受体激动剂，用于治疗心动过缓和心传导阻滞。 |
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| S2020 |
Formoterol HemifumarateFormoterol Hemifumarate是一种有效的，选择性的，长效β2-adrenoceptor 激动剂，用于治疗哮喘以及慢性阻塞性肺病。 |
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| S2521 |
Epinephrine bitartrateEpinephrine Bitartrate 是一种α和β-肾上腺素能受体激动剂。 |
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| S2458 |
Clonidine HClClonidine HCl 是一种直接起作用的α2肾上腺素能受体激动剂，ED50为0.02±0.01 mg/kg。 |
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| S3041 |
DroxidopaDroxidopa是一种精神药物，是合成的氨基酸前体，它作为神经传导物质去甲肾上腺素和肾上腺素的前药来发挥作用。 |
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| S3075 |
DexmedetomidineDexmedetomidine是特护病房和麻醉师使用的一种镇静剂。 |
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| S2522 |
L-AdrenalineL-Adrenaline属于儿茶酚胺类。 |
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| S2569 |
Phenylephrine HClPhenylephrine HCl是一种选择性的α1-肾上腺素能受体激动剂。 |
(F) Fluo-4 AM-loaded EPLC-SMCs and HCASMCs displayed a change in cell surface area following phenylephrine stimulation. Scale bars, 100 μm. (G) Percentage change in cell surface area. Error bars represent SEM; n = 12 cells; **p < 0.01 versus D15 + 8 + 6 cells that did not exhibit calcium transients, analyzed by the Student's t-test. HCASMCs, human coronary artery smooth muscle cells; NS, no significant difference.
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| S4065 |
Guanabenz AcetateGuanabenz Acetate是一种选择性的α2a-肾上腺素能受体， α2b-肾上腺素能受体和α2c-肾上腺素能受体激动剂，pEC50分别为8.25， 7.01和5左右。 |
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| S2519 |
Naphazoline HClNaphazoline HCl 是一种眼部血管收缩剂，是咪唑啉衍生的拟交感胺类。 |
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| S2533 |
Ritodrine HClRitodrine HCl 是Ritodrine的盐酸盐，是β-2肾上腺素能受体激动剂。 |
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| S2438 |
Synephrine HClSynephrine HCl是一种交感神经α-adrenergic receptor (AR)（肾上腺素受体）激动剂。 |
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| S2090 |
Dexmedetomidine HClDexmedetomidine HCl 是一种有效的，高度选择性α-2肾上腺素受体激动剂，具有显著的镇静效果，从而降低患者的麻醉量。 |
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| S3061 |
Epinephrine HClEpinephrine HCl是一种激素和神经递质。 |
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| S3060 |
Medetomidine HClMedetomidine HCl是一种选择性的α2-adrenoceptor（α2-肾上腺素受体）激动剂，Ki为1.08 nM，比作用于α1-adrenoceptor选择性高1620倍。 |
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| S1437 |
Tizanidine HClTizanidine HCl是一种α2-肾上腺素受体，抑制中枢神经系统去甲肾上腺素能神经的神经递质的释放。 |
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| S2092 |
Detomidine HClDetomidine HCl可产生镇静和镇痛作用，这种作用具有剂量依赖性，通过激活α2儿茶酚胺受体来调节。 |
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| S2545 |
ScopineScopine是Anisodine的代谢产物，是一种α1-肾上腺素能受体激动剂，用于治疗急性循环性休克。 |
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| S4296 |
Salmeterol XinafoateSalmeterol Xinafoate是一种长效的β2-adrenergic receptor激动剂，具有抗炎作用，用于哮喘症状和慢性阻塞性肺疾病（COPD）症状的治疗。 |
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| S2523 |
DL-AdrenalineDL-Adrenaline是一种激素，是由肾上腺髓质分泌的一种神经递质。 |
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| S4266 |
Brimonidine TartrateBrimonidine Tartrate是一种高选择性的α-肾上腺素能受体激动剂，EC50为0.45 nM，用于治疗开角型青光眼或高眼压症。 |
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| S2615 |
Noradrenaline bitartrate monohydrateNoradrenaline bitartrate monohydrate 是一种直接的α-肾上腺素能受体激动剂。 |
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| S7974 |
L755507L-755,507是一种有效的、选择性的β3肾上腺素能受体部分激动剂，EC50为0.43 nM。它能在iPSCs和其他细胞类型中增强CRISPR介导的同源重组修复效率。 |
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| S4127 |
Terbutaline SulfateTerbutaline Sulfate是一种选择性的β2-肾上腺素能受体激动剂，IC50为53 nM。 |
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| S4135 |
Clorprenaline HClClorprenaline HCl是β2-受体激动剂，具有显著的扩张支气管作用。 |
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| S4043 |
Tetrahydrozoline HClTetrahydrozoline HCl是一种咪唑啉衍生物，具有α受体激动剂活性。 |
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| S2576 |
Xylometazoline HClXylometazoline HCl 是α-adrenoceptor激动剂，常用作鼻血管收缩药，高效作用于α2B肾上腺素受体亚型，EC50为4 μM。 |
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| S4693 |
Guanfacine HydrochlorideGuanfacine Hydrochloride是一种选择性的α2A-肾上腺素受体激动剂，具有降压效果。 |
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| S4277 |
Bambuterol HClBambuterol HCl是强效β-adrenoceptor拮抗剂，用于治疗哮喘。 |
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| S2362 |
SynephrineSynephrine是从苦橘及其他柑橘属植物中提取的一种不饱和的植物甾醇，常用于减肥。 |
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| S3185 |
Adrenalone HClAdrenalone HCl是一种肾上腺素激动剂，作为外用的血管收缩剂和止血剂，主要作用于α-1肾上腺素受体。 |
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| S4243 |
Deoxycorticosterone acetateDeoxycorticosterone acetate是一种类固醇激素，用于肌肉注射，是肾上腺皮质类固醇的代替疗法。 |
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