Navitoclax (ABT-263)

For research use only. Not for use in humans.

目录号：S1001

CAS No. 923564-51-6

Navitoclax (ABT-263)是一种有效的Bcl-xL，Bcl-2和Bcl-w抑制剂，无细胞试验中K_i分别为≤0.5 nM，≤1 nM和≤1 nM，但与Mcl-1和A1结合微弱。Phase 2。

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10mM (1mL in DMSO)	RMB 3285.53	现货
5mg	RMB 975.71	现货
25mg	RMB 3016.58	现货
100mg	RMB 7950.36	现货
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客户使用Selleck生产的Navitoclax (ABT-263)发表文献222篇：

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Nat Cell Biol, 2020, 4

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Sci Rep, 2015, 5:14739

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PLoS One, 2015, 10(3):e0120913

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Microvasc Res, 2015, 101:72-81

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Sci Rep, 2015, 5:16406

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Haematologica, 2013,

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Neoplasia, 2013, 15(5):568-78

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Helsinki Metropolia University, 2013, Jens Desloovere

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Clin Cancer Res, 2010, 16(16):4217-25

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产品安全说明书

Bcl-2抑制剂选择性比较

生物活性

产品描述

Navitoclax (ABT-263)是一种有效的Bcl-xL，Bcl-2和Bcl-w抑制剂，无细胞试验中K_i分别为≤0.5 nM，≤1 nM和≤1 nM，但与Mcl-1和A1结合微弱。Phase 2。

靶点

Bcl-xL ^[1] (Cell-free assay)	Bcl-2 ^[1] (Cell-free assay)	Bcl-w ^[1] (Cell-free assay)
<=0.5 nM(Ki)	<=1 nM(Ki)	<=1 nM(Ki)

体外研究

ABT-263有效抑制Bcl-2蛋白家族，用荧光偏振分析法测试ABT-263作用于Bcl-xL, Bcl-2和 Bcl-w时，K_i分别为0.5, 1和1 nM。^[1]ABT-263结构上与ABT-737相关。ABT-263阻断Bcl-2 和Bcl-XL与凋亡前体蛋白相互作用。Bcl-2家族成员Bcl-2,Bcl-XL, 和Mcl-1的过量表达通常都与肿瘤的修复及抗药性有关。ABT-263作用于过量表达的Bcl-2 和Bcl-XL时显示出保护作用，EC50分别为60 和20 nM。ABT-263作用于不同的细胞显示出不同的细胞活性，作用于H146细胞系时EC50为110nM,而作用于H82细胞系时EC50为22 µM。ABT-737可以有效作用于四种EC50值 <400 nM的细胞系，即H146, H889, H1963, 和H1417。而两种抗ABT-737的细胞系，即H1048和H82，同样也显示出抗ABT-263的特性。^[2]

Cell Data

Cell Lines	Assay Type	Incubation Time	Activity Description	PMID
FL5.12	M1HBcGN6fG:2b4jpZ4l1gSCjc4PhfS=>	NYPyUFZmOjRiaB?=	MWrFR\|UxKD1iMD6wNFQzKM7:TR?=	MkDoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh6NEG4PFIoRjF6OESxPFgzRC:jPh?=
FL5.12	M1n5S2N6fG:2b4jpZ4l1gSCjc4PhfS=>	NXe0OlBuOjRiaB?=	MmX3SWM2OCB;IECuNFA2QSEQvF2=	M1LiXVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6OESxPFgzLz5zOEi0NVg5OjxxYU6=
RS4:11	MVvBdI9xfG:\|aYOgZZN{[Xl?	M4\VU\|YhcA>?	NHTZZmNGSzVyIE2gNE4xOTRizszN	NHzicYk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEi4NVU3Pyd-MkS4PFE2Pjd:L3G+
FDC-P1	NWPVbIY1SkOOLUKgbY5pcWKrdHnvckBie3OjeR?=	MVuyOEBp	M1ftRmlEPTBiPTCwMlAyPSEQvF2=	NGLTVlA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEi4NVU3Pyd-MkS4PFE2Pjd:L3G+
NCI-H1963	MmDkR5l1d3SxeHnjbZR6KGG\|c3H5	M3zjZVQh\GG7cx?=	MVPJR\|UxKD1iMD6wNlY3KM7:TR?=	NYrCSWpRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO0OFgzQThpPkKzOFQ5Ojl6PD;hQi=>
NCI-H187	M1vyZWN6fG:2b4jpZ4l1gSCjc4PhfS=>	M1Tob\|Qh\GG7cx?=	M{GzWmlEPTBiPTCwMlA{QDRizszN	M{m1elxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ\|NES4Nlk5Lz5{M{S0PFI6QDxxYU6=
NCI-H1417	MUPDfZRwfG:6aXPpeJkh[XO\|YYm=	NVTXeo57PCCmYYnz	M1rUbWlEPTBiPTCwMlA2PDJizszN	NWqxdnNlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO0OFgzQThpPkKzOFQ5Ojl6PD;hQi=>
FDC-P1	NIXGdW5DS0xveFygbY5pcWKrdHnvckBie3OjeR?=	MVqyOEBp	NXHhdYR2UUN3MDC9JFAvODZizszN	M1\LdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OEixOVY4Lz5{NEi4NVU3PzxxYU6=
NCI-H146	NVXVUZhzS3m2b4TvfIlkcXS7IHHzd4F6	M336OlQ5KGh?	Ml[zSWM2OCB;IECuNFg3PyEQvF2=	NV3tNHNuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi4OFE5QDJpPkG4PFQyQDh{PD;hQi=>
RS4:11	NGHqT\|NCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		MUDFR\|UxKD1iMD6xNVIh\|ryP	MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDl{NkK0O{c,Ojh7Mk[yOFc9N2F-
MOLT4	NVeydmtjSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=		MlPWSWM2OCB;IECuN\|A{KM7:TR?=	NVzs[WVuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki5NlYzPDdpPkK4PVI3OjR5PD;hQi=>
EoL-1-cell	NWrUU3VoT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		NYXxSG8xUUN3ME2wMlAxPjZ7IN88US=>	M3y2cFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
MV-4-11	NV6yXW1TT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		MWXJR\|UxRTBwMEG1PFYh\|ryP	NEnlRnQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
NKM-1	NHvWW3VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		M{TXe2lEPTB;MD6wNVY6QSEQvF2=	MmXjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
ML-2	MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		M{DzN2lEPTB;MD6wNVk5OyEQvF2=	M3:3RVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
BV-173	NXTTfIJKT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		MX;JR\|UxRTBwMEKzNVQh\|ryP	NVvTfpc5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
RS4-11	MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MVHJR\|UxRTBwMEK1PFch\|ryP	M125TVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
HL-60	NIfxdJNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		NUjrRnhkUUN3ME2wMlAzQTB6IN88US=>	MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
KY821	NIDwPGhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		NUXSRXBuUUN3ME2wMlAzQTd3IN88US=>	M3OwNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
ECC10	NULNU3dlT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		MorlTWM2OD1yLkCzO\|kzKM7:TR?=	NYfsc5NrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
NCI-H720	MnnGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NYjST4YxUUN3ME2wMlA1ODFzIN88US=>	NI\1eXk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
QIMR-WIL	NFr0WopIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		MYHJR\|UxRTBwMESyPFch\|ryP	M4nNVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
KG-1	MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MU\JR\|UxRTBwMES0PFYh\|ryP	NHfyc5M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
TGW	MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		Mmi2TWM2OD1yLkC0OlM{KM7:TR?=	Mn2zQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
ATN-1	MnXQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NFPuUGxKSzVyPUCuNFQ4OzNizszN	MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
RH-18	M3nHWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		M2\2XWlEPTB;MD6wOlA1QCEQvF2=	NEO5S2I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
EW-18	NHXURlJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		MnTOTWM2OD1yLkC2PFQyKM7:TR?=	MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
NB17	NGTXfoFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		NELycXNKSzVyPUCuNFcyOjRizszN	NIXCNmc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
SK-NEP-1	M1LRcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		NIfOcFJKSzVyPUCuNFczOTNizszN	M{nae\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
P12-ICHIKAWA	MojsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NFfPb45KSzVyPUCuNFc4PzhizszN	M3TTZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
KARPAS-45	MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		M1r2eWlEPTB;MD6wO\|gyPSEQvF2=	MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
EW-3	M3XE[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		NFjYdFhKSzVyPUCuNFgxPTNizszN	NFHjPIk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
NB13	M3rpW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7		MYLJR\|UxRTBwMEiyNFMh\|ryP	MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
NCI-H209	MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NFnN[JFKSzVyPUCuNFg4ODRizszN	M4\KcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
NCI-H1092	MonGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MlXCTWM2OD1yLkGwNlc2KM7:TR?=	MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
NH-12	NH;mPZNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		NEPDW2pKSzVyPUCuNVA4PDRizszN	M2X4W\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
697	MkHKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		M37jWWlEPTB;MD6xNFg{QSEQvF2=	NFT0Wm89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
KE-37	M4SzdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		NVLIN\|REUUN3ME2wMlEyOzdizszN	M1zDVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
MOLT-4	M3fuN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7		NF[zSYFKSzVyPUCuNVUyPjlizszN	NFf2[4U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
CHP-134	NIfiOWJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		NIjNVotKSzVyPUCuNVY{ODZizszN	NFzXR5U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
D-283MED	NUjGV4pRT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		MVrJR\|UxRTBwMUe2PFYh\|ryP	NVz3fI04RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
LU-135	MnnpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MkXiTWM2OD1yLkG4OVUzKM7:TR?=	MljNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
LU-134-A	MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NXLDNXZJUUN3ME2wMlE5PjdzIN88US=>	MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
EM-2	NYXBc2RQT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		MnjrTWM2OD1yLkG5PVE5KM7:TR?=	MlfWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
LU-139	MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NUnHVm03UUN3ME2wMlIxPDl6IN88US=>	MorOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
ALL-PO	NWfid5VXT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		NXvNR25OUUN3ME2wMlIyQTh6IN88US=>	M2DGO\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
NB12	MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		M2G1XGlEPTB;MD6yN\|EyPSEQvF2=	M1jiWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
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BB65-RCC	MliwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		M4PrXmlEPTB;ND6wOFM6QSEQvF2=	MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
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LK-2	NWLF[21iT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		MnHFTWM2OD12LkGxNlk{KM7:TR?=	NYLlR4h3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
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RPMI-7951	Mm\0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NHPTXYZKSzVyPUSuNlI1OTNizszN	NVvUTIxjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
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LAN-6	MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MlfZTWM2OD12LkS1NVg6KM7:TR?=	M3TxelxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
FTC-133	M1fWcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		MofrTWM2OD12LkWzPVUh\|ryP	M2mzOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
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NCI-H1623	NXjhNVl4T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		M4jaTmlEPTB;ND63NFIzQCEQvF2=	MkLhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
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UMC-11	M2fibWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		NYrs[2lRUUN3ME20Mlg5QTZ2IN88US=>	M{Hkb\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
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NCI-H2029	NYDCZXFsT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		NGLTSXVKSzVyPUSuPVQyQDVizszN	MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
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KINGS-1	Mom4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NHfhWoFKSzVyPUWuNFc4PDRizszN	NGnaeVQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
HD-MY-Z	MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MVHJR\|UxRTVwMkO5Olkh\|ryP	MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
ESS-1	M3m5cmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		M37yUWlEPTB;NT6yOVU6PyEQvF2=	NWKxXXhTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
GI-1	MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		Ml3RTWM2OD13LkK3PVI3KM7:TR?=	NXPmeoFrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
RPMI-2650	M4Lyemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		NWiy[JR2UUN3ME21MlM3OTZizszN	NVPyZVFCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
IA-LM	MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MWPJR\|UxRTVwM{m4O\|Eh\|ryP	NETJNlE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
KP-4	MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		Mo\aTWM2OD13LkS2N\|M1KM7:TR?=	NVKzSHlORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
G-402	NIXEb2pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		NWjkPIlNUUN3ME21MlUyQDZ3IN88US=>	NWqyd\|V3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
OS-RC-2	M3;qcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		MW\JR\|UxRTVwNUK2NFQh\|ryP	Mnr4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
NCI-H1155	M{i1TGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		MWnJR\|UxRTVwNUS5OVUh\|ryP	NIjHOFc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
OE19	M1fqW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7		M3HaTWlEPTB;NT62PFYzPCEQvF2=	NVfTb4ZWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
U-2-OS	MmPQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NV\WZVFqUUN3ME21Mlg6ODF\|IN88US=>	NIXZRZo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
SCC-15	MnvNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		M{fQTWlEPTB;NT65N\|Y3OiEQvF2=	M1rVS\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
NCI-H630	MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MmC3TWM2OD13Lkm5OFA1KM7:TR?=	M3zVUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
PFSK-1	M162N2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7		NYTF[GUyUUN3ME22MlA2OjV7IN88US=>	Ml30QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
NCI-H1770	M2XXOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		NE\YdJdKSzVyPU[uNlA5PzRizszN	NFLiOmc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
SK-MEL-3	M3TvbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		NFLwUHZKSzVyPU[uOFI6OTVizszN	MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
LB1047-RCC	NX;ONJZCT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		NEDJU5hKSzVyPU[uOFc3OjVizszN	NVqzfotxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
NCI-H446	NYX4S3VpT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		NHH2bW9KSzVyPU[uOlI6OjVizszN	M1rqe\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
SW780	M17UeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		NUD3SGlPUUN3ME22MlcxOTh3IN88US=>	MoPhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
NEC8	NFzhWZNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		M1LkeWlEPTB;Nj63OlY{KM7:TR?=	MkHQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
NOMO-1	NHfFR3lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		NWLwOWhHUUN3ME22Mlc5OTFzIN88US=>	NF3pd5Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
COLO-668	M{j0TWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		NH6zW4FKSzVyPU[uPFQ{QDdizszN	NWPrTWdnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
MC116	NIP2[YZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		MmPkTWM2OD14LkmzPFk4KM7:TR?=	NUnRfWd2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
HCC1937	M3r1eGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		M1XPTmlEPTB;Nj65PVI2OSEQvF2=	Ml7SQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
NCI-N87	NVqxZpN2T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		NHnjZ2xKSzVyPUeuNVkzQTNizszN	M2fGNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
COLO-320-HSR	MoH4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MnrsTWM2OD15LkKyO\|M5KM7:TR?=	MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
HCC1806	MoG0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MnXzTWM2OD15LkK2NFQ1KM7:TR?=	M1n6[\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
OVCAR-3	MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NY[1UXh3UUN3ME23MlM{ODN6IN88US=>	MkH3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
NUGC-3	M3zZPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		NWG1NZFWUUN3ME23MlM6Pjl2IN88US=>	MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
SW1783	NULHXGpWT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		M{PrUmlEPTB;Nz60N\|E4PSEQvF2=	M4fPbVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
GCT	NXHWN4o1T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		MWnJR\|UxRTdwNU[5NFYh\|ryP	NYm2O206RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
NCI-H2126	M4njcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		M2C2eGlEPTB;Nz63N\|YzPSEQvF2=	MmnNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
MEL-HO	MnP3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NFi5SopKSzVyPUeuO\|cxPTRizszN	NIrkOHI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
CAPAN-1	MoXQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NHnKWWhKSzVyPUeuO\|c{PTdizszN	M1i1V\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
SW756	M{HkdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		M{X4[mlEPTB;Nz63PFM{OyEQvF2=	M1H3bFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
SKG-IIIa	MmTxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NXfRSm1RUUN3ME23MlgyQDl{IN88US=>	MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
HCE-T	MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NXnmRXhUUUN3ME23Mlg4Pzh\|IN88US=>	MoDNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
Ca-Ski	MmnXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MVzJR\|UxRTdwOUmzPFMh\|ryP	M3H0RVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
COLO-684	MkPkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		M4PybGlEPTB;OD6wNVgyQCEQvF2=	MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
KYSE-70	M{Xjfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		M2LMOGlEPTB;OD6wO\|czQSEQvF2=	NXv4dHpLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
TI-73	MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NXn2NIl4UUN3ME24MlI2QDVzIN88US=>	M3TNUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
BT-20	NWLDSm1WT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		MXPJR\|UxRThwMk[wOVIh\|ryP	NY[wXnBERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
MHH-ES-1	NGfh[2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		MVfJR\|UxRThwNUG4N\|Qh\|ryP	MofFQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
TE-12	MoL3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MonITWM2OD16LkW5PVMyKM7:TR?=	NVnTSIg5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
YH-13	Ml32S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MYLJR\|UxRThwNkGwNFgh\|ryP	MmTPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
SF126	MnPrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MV\JR\|UxRThwOEO4OlUh\|ryP	Mkj3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
J82	MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MYfJR\|UxRThwOUCwN\|gh\|ryP	NHPzR489[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
RCC10RGB	MkTsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NYXlfYk1UUN3ME24Mlk6PTZzIN88US=>	NVrnfVZDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
SK-UT-1	MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NWPoSnVUUUN3ME25MlA1QTR3IN88US=>	NHr3dmI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
LB2241-RCC	MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MU\JR\|UxRTlwMUmxN\|ch\|ryP	MkLyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
LB996-RCC	MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MkPhTWM2OD17LkG5PFkh\|ryP	MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
EPLC-272H	NXzMZ4tsT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		NWPjd2diUUN3ME25MlM4PjV5IN88US=>	MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
CTV-1	MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MYLJR\|UxRTlwNU[1N\|Ih\|ryP	NFX3cok9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
HSC-2	MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NE\hR45KSzVyPUmuOVc2PSEQvF2=	MkXZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
SK-MEL-28	NHfUVZRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		MkHUTWM2OD17Lk[xPFk{KM7:TR?=	MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
MMAC-SF	MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		Mk\QTWM2OD17Lk[4O\|Uh\|ryP	Mnj5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
CP50-MEL-B	M4T1RWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		M1rFfGlEPTB;OT63OVc5OiEQvF2=	NF;3XpM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
HT-1080	NXWyR3d6T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		NX\ROWlpUUN3ME25Mlc4PzN7IN88US=>	M{\PfFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
HEC-1	Mn7QS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NV\YSVREUUN3ME2xNE4{OzV{IN88US=>	NXPOTXpYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
AGS	NHXjeG5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		M3LRWmlEPTB;MUCuN\|c1KM7:TR?=	MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
GAMG	Mn\qS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		Ml7qTWM2OD1zMD61NVYzKM7:TR?=	M4jBTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
SW48	MoXmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MVXJR\|UxRTFyLkWxPFkh\|ryP	MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
U031	M3rRcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		M{fBPGlEPTB;MUCuOVkxQCEQvF2=	MkDXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
OVCAR-5	MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NGrtTGVKSzVyPUGwMlY1OjlizszN	M2fWOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
SF295	NG\yOGNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		MYXJR\|UxRTFyLk[3NFQh\|ryP	NFTHe4s9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
BHT-101	Mme1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NIntO2JKSzVyPUGwMlcyPzdizszN	MnH3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
VMRC-RCZ	NU\l[Id1T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		NFv0[FRKSzVyPUGxMlMzODFizszN	M3qxXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
ACHN	MnHpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NVfQO4FPUUN3ME2xNU41OjFzIN88US=>	MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
NCI-H526	M4nuO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7		MnfVTWM2OD1zMT61NFQ{KM7:TR?=	NV;tTGZsRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
MN-60	MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MkLOTWM2OD1zMT61N\|kh\|ryP	NI[zb\|M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
NCI-H2291	NITYRotIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		NYPHZlZtUUN3ME2xNU42PDZ4IN88US=>	M3i5TFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
SCC-25	MmC1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NF3oZZhKSzVyPUGxMlc2PTZizszN	MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
SK-MEL-2	MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		M2HqfmlEPTB;MUGuO\|Y{PyEQvF2=	NWnHUIkyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
SN12C	MoPXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MX3JR\|UxRTFzLkmzOVUh\|ryP	MkHVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
NCI-H69	MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MlK5TWM2OD1zMj60NlM1KM7:TR?=	MmTlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
ME-180	MknLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MVfJR\|UxRTF{LkewOVQh\|ryP	MlzUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
MC-IXC	NFr2c4FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		Mm\aTWM2OD1zMj63OVE5KM7:TR?=	NXzMVY9VRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
NCI-H2347	MmfXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NH7rfWNKSzVyPUGyMlc3OTRizszN	NYmzcmExRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
M059J	MmDiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MnW2TWM2OD1zMj63O\|I4KM7:TR?=	NWfCOGhuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
A2058	NH3uNYlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		MWXJR\|UxRTF{Lki2PFEh\|ryP	NYHndpB[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
VA-ES-BJ	MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MV7JR\|UxRTF{Lki3PFUh\|ryP	M2nEXVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
Ca9-22	MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MVjJR\|UxRTF{Lkm0OVEh\|ryP	MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
KNS-42	MmO2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NH\oSHVKSzVyPUGyMlk6QDRizszN	Ml34QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
LoVo	M3Sx[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		MVLJR\|UxRTF\|LkKzNVMh\|ryP	M3;Ce\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
AM-38	NFnhSY1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		MVfJR\|UxRTF\|LkK1OlYh\|ryP	NVm3V3NHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
NB5	MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MUPJR\|UxRTF\|LkO3OVIh\|ryP	MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
L-363	M2G1PGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		M3\oT2lEPTB;MUOuOFA{OyEQvF2=	Mof3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
SK-MEL-30	NYHiVVBFT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		NYPmZVFjUUN3ME2xOE4xPjR3IN88US=>	NGrKcos9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
NCI-H1563	NG\2W3VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		NYT5c2FqUUN3ME2xOE43ODN7IN88US=>	MkPTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
NCI-H2228	M3vmbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		MXHJR\|UxRTF2Lk[wO\|ch\|ryP	NWP2OW94RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
MFM-223	MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NVLXWnZlUUN3ME2xOU4yQDF\|IN88US=>	M3PZfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
LB831-BLC	Mn3SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NUfaVWdFUUN3ME2xOU4zPzZ5IN88US=>	MlrsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
SW872	NUTmNFBNT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		M3;FfmlEPTB;MUWuN\|A5PiEQvF2=	MoXaQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
NCI-H522	Mon3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NXj0SmhWUUN3ME2xOU4{OzB4IN88US=>	MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
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NCI-H292	NXHvS2NYT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		M4fGWGlEPTB;MkWuN\|U{PiEQvF2=	M4TSU\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
COLO-680N	MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NVPVbHVkUUN3ME2yOU43OzJ7IN88US=>	MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
KYSE-520	M1fTbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		MUnJR\|UxRTJ3Lk[0OEDPxE1?	NGX3SGM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
NB10	MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MVrJR\|UxRTJ4LkOxNVch\|ryP	MmTkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
NCI-H661	Mn\1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		M4rjSGlEPTB;Mk[uOFcyOyEQvF2=	MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
GMS-10	MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NWO2[4dqUUN3ME2yOk45PjN6IN88US=>	NEf3N4o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
NCI-H2122	NEW4U4ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		NV3QOHV{UUN3ME2yOk46QTl6IN88US=>	NYPWfIRjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
OVCAR-8	MmHSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NF7Ie45KSzVyPUK3MlA3OzhizszN	MojDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
DJM-1	MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		M3fseGlEPTB;MkeuNVQ2PCEQvF2=	NWTU[JhLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
UACC-893	M{fLPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		Mlz1TWM2OD1{Nz65PFc5KM7:TR?=	M2jNUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
C8166	NXfNS\|RlT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		NETP[3RKSzVyPUK4MlY6OzhizszN	M2PDNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
NCI-H1693	Mm\vS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		M4jmNWlEPTB;MkiuOlk4PSEQvF2=	MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
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SW1710	Mo[0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NXfL[WJjUUN3ME2zNE4yOjZizszN	M2PDWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
A375	MkTaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MYHJR\|UxRTNyLkOyOFMh\|ryP	Ml3nQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
HMV-II	NWnz[2g4T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		MkCzTWM2OD1\|MT6zOVkzKM7:TR?=	Ml\KQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
NCI-H2087	NXTqTmtKT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		Mn34TWM2OD1\|MT62N\|UzKM7:TR?=	Mnv1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
CAL-54	NXHMfZl3T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		M{n6UWlEPTB;M{GuO\|I1OSEQvF2=	MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
HCC70	MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NEHiOWZKSzVyPUOyMlE{QDdizszN	MnqyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
ES1	NYD2UIxjT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		MmLUTWM2OD1\|Mj6zNFYzKM7:TR?=	M3jhcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
NCI-H1355	MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NF25UZFKSzVyPUOzMlIxPCEQvF2=	M4\POFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
CFPAC-1	MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MWfJR\|UxRTN\|LkKzN\|Ih\|ryP	M3TWNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
MKN28	NEPkblVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		Mo\MTWM2OD1\|Mz6zPFA6KM7:TR?=	M1\LNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
HDLM-2	NWHhW4s6T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		NIrKSlBKSzVyPUOzMlY6OzFizszN	NHPrSY49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
PANC-10-05	NWKxRZpGT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		MXTJR\|UxRTN2LkGwNVQh\|ryP	MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
SAS	NHnHXJRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		MnPsTWM2OD1\|ND60OVY2KM7:TR?=	NEPTTIk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
HCC1395	MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NHnYTZpKSzVyPUO0MlcyQDZizszN	NGrJelQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
8305C	MlfIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NX;TPW52UUN3ME2zOU45PDF3IN88US=>	M1[yN\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
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SW1116	NHXidpNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		MXHJR\|UxRTN5LkW5PVIh\|ryP	MkS5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
SK-MEL-1	MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NGn4fHJKSzVyPUO4MlM{QDlizszN	NHfHd4M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
HCC2218	NYfGOnNyT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		NVTDTZZMUUN3ME2zPE43PTF7IN88US=>	NHrsZZM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
T84	NFrJO4JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		MVfJR\|UxRTN6Lke0NFkh\|ryP	NHuyZYc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
ETK-1	M2K5SWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		M{mwOWlEPTB;M{muNFIzKM7:TR?=	NEDNWoc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
COLO-800	MkjMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MVTJR\|UxRTN7LkO4Olgh\|ryP	M3:1b\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
CAL-12T	NUHMVVZqT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		MnXZTWM2OD1\|OT61NlgyKM7:TR?=	MlT2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
ACN	NHTiSXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		NIPi[YRKSzVyPUSwMlQ6OTFizszN	M3S1XFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
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Saos-2	NVLCSoJmT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		NYTrdpJtUUN3ME20Nk45OzZ7IN88US=>	NIrhOpE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
SNU-C2B	NYXxWIFqT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		MnnhTWM2OD12Mz62PFc5KM7:TR?=	M1LIVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
HLE	MknrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MljiTWM2OD12ND6wPFU3KM7:TR?=	MknkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
SW1463	MmHWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		M3nFdGlEPTB;NESuPVk4OSEQvF2=	MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
DSH1	M2nyeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		M{ixWGlEPTB;NEWuNFA{OyEQvF2=	MnX2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
MCF7	NV:3NI9rT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		M4C2dmlEPTB;NEWuOVA2OSEQvF2=	NFftW3Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
K5	NFLlNlVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		M13HWGlEPTB;NEWuPVQxPSEQvF2=	NGjIRpU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
NCI-H358	MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NYTIUmpTUUN3ME20O{4zOTVizszN	MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
NCI-H2030	NH\y[4hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		NWHxVoJRUUN3ME20O{4zOzd2IN88US=>	NI\hNpk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
SW948	MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MXLJR\|UxRTR5LkS2OEDPxE1?	NEfu[VA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
BALL-1	M4\0Smdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		NW\OOHBjUUN3ME20O{43OTZ6IN88US=>	MlHOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>
TE-9	M2nacGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		NG\0eGpKSzVyPUS3Mlk2QDFizszN	MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0OFM3QDRxJ{7TRW5ITVJ:L3G+
SK-N-FI	NGTVPJNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		M4\CZ2lEPTB;NEiuNFM2QCEQvF2=	NILRPVU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
KALS-1	MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MnKwTWM2OD12OD6xNlg6KM7:TR?=	NVfEZ2tPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDR\|Nki0M{c,W0GQR1XSQE9iRg>?
HO-1-N-1	MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NVHreVNHUUN3ME20PE44PDR3IN88US=>	M{jBZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQ1OzZ6ND:nQnNCVkeHUkyvZV4>
NCI-H2452	MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NHvLbm1KSzVyPUS5MlEyPTJizszN	NIf4R4o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1PDN4OESvK\|5USU6JRWK8M4E,
OC-314	MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NELzflVKSzVyPUS5MlY5OzRizszN	MoG5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFQ{Pjh2Lze+V2FPT0WUPD;hQi=>

... Click to View More Cell Line Experimental Data

Assay

Methods	Test Index	PMID
Western blot	STAT3 / pSTAT3 / STAT6 / pSTAT6 / Mcl-1 / Cleaved Mcl-1 / Bcl-xl / Bim / puma / Bik / Bax / PARP / c-Myc; PubMed: 26811457 Proc Natl Acad Sci U S A (A) Western blot analysis of expressions of STAT3/p-STAT3 and STAT6/p-STAT6 as well as antiapoptotic members (Bcl-2, Bcl-xL, and Mcl-1) after 48 h of treatments in HDLM-2 cells. (B) Western blot analysis of expressions of proapoptotic proteins (Bim, Puma, Bik, Bax, and p-Bad) as well as caspase cascade molecules (PARP and c-Myc) after 48 h of treatments. β-Actin was used as an input control. caspase3 / cleaved caspase 3; PubMed: 24481442 Cell Death Dis (b) (i) N/TERT, (ii) SINCE and (iii) SINEG2 cells were either untreated (0 μM/DMSO) or treated with increasing doses of Navitoclax (ABT-263; 0.025–30 μM) and were incubated for 24 h. Next, cells were collected and whole-cell lysates were prepared and immunoblotted against anti-full-length Caspase 3 (∼35 kDa) antibody, whereas β-actin (∼42 kDa) was used as a protein-loading control. Apoptosis was assessed through detecting the cleaved bands of Caspase-3 (∼19, 17 kDa).	26811457 24481442
Growth inhibition assay	Cell viability; PubMed: 25685063 Cancer Cell Int (C) Hcc827, (D) H292, and (E) H1993 cells were treated with increasing concentrations of albendazole or mebendazole in the presence of navitoclax (0, 1, 2, and 4 μM). Viability was determined after 1 day.	25685063

体内研究

用ABT-263处理H345移植瘤模型，按动物体重，每千克每天处理10mg ABT-263，结果肿瘤生长抑制率达80% ，肿瘤体积减小了50%以上，显示出ABT-263极强的抗癌效果。ABT-263作用于非小细胞肺癌和急性淋巴细胞白血病的移植瘤模型时，每天单独口服，结果显示肿瘤完全衰退。ABT-263单独作用于B-细胞淋巴瘤和多发性骨髓瘤的移植瘤模型时效果不明显，但是可以显著增强临床其他相关用药的药性。^[2]

激酶实验： ^[1]	- 合并激酶实验: 用竞争性荧光偏振检测测定ABT-263 作用于Bcl-2 家族不同亚型的Ki值或者IC50值。使用如下的肽探针对或者蛋白对：f-bad (1 nM) 和Bcl-xL (6 nM), f-Bax (1 nM) 和Bcl-2 (10 nM), f-Bax (1 nM) 和Bcl-w (40 nM), f-Noxa (2 nM)和Mcl-1 (40 nM), 及f-Bax (1 nM) 和Bcl-2-A1 (15 nM)。用时间分辨荧光共振能转移法测定ABT-263和Bcl-xL作用的结合紧密度。1 nM 用His标记的Bcl-xL 与200 nM f-Bak,及 1 nM Tb标记的His抗体混合, 然后在室温下处理30分钟。
细胞实验： ^[1]	- 合并 Cell lines: SCLC 细胞系 Concentrations: 0-1 μM Incubation Time: 48小时 Method: 人类肿瘤细胞系在37^oC 含5% CO₂环境下获得，SCLC 细胞系培养在RPMI 1640培养基中，培养基包含10% 胎牛血清, 1% 丙酮酸钠, 25 mM HEPES, 4.5 g/L葡萄糖, 1% 青霉素/链霉素。用含有10% FBS和1% 青霉素/链霉素的RPMI 1640培养基培养白血病和淋巴癌细胞系。细胞在96孔板上处理48小时，最终体积达到100ul。在体外测试ABT-263的细胞毒性。 (Only for Reference)
动物实验： ^[1]	- 合并 Animal Models: C.B.-17严重联合免疫缺陷-米黄鼠 Dosages: 100 mg/kg/d Administration: 口服处理 (Only for Reference)

参考文献

溶解度 (25°C)

体外	DMSO	100 mg/mL (102.6 mM)
	Water	Insoluble
	Ethanol	Insoluble
体内	从左到右依次将纯溶剂加入产品，现配现用(数据来自Selleck实验检测而非文献)： 5% DMSO+corn oil	7mg/mL

* 溶解度检测是由Selleck技术部门检测的，可能会和文献中提供的溶解度有所差异，这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据 Download Navitoclax (ABT-263) SDF

分子量	974.61
化学式	C₄₇H₅₅ClF₃N₅O₆S₃
CAS号	923564-51-6
储存条件	3年-20°C 粉状 2年-80°C 溶于溶剂
别名	N/A

动物体内配方计算器 (澄清溶液)

第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量）

给药剂量

mg/kg

动物平均体重

每只动物给药体积

动物数量

只

第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系Selleck为您提供正确的澄清溶液配方）

% DMSO+ % + % Tween 80+ % ddH₂O

计算重置

计算结果:

工作液浓度： mg/ml；

DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，注：如该浓度超过该批次药物DMSO溶解度，请先联系Selleck）；

体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL ddH₂O，混匀澄清。

注意：1. 首先保证母液是澄清的；
2. 一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。

计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为:

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

质量

浓度

体积

分子量
=

×

×

*在配置溶液时，请务必参考Selleck产品标签上、MSDS / COA（可在Selleck的产品页面获得）批次特异的分子量使用本工具。

稀释计算器

用本工具协助配置特定浓度的溶液，使用的计算公式为：

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入输出 )

C1

V1

C2

V2
×

=

×

在配置溶液时，请务必参考Selleck产品标签上、MSDS / COA（可在Selleck的产品页面获得）批次特异的分子量使用本工具。.

连续稀释计算器方程

连续稀释
初始浓度:
稀释倍数:

计算结果

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):

分子量计算器

通过输入化合物的化学式来计算其分子量：

注：化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量	浓度	体积	分子量
=	×	×
计算

技术支持

在订购、运输、储存和使用我们的产品的任何阶段，您遇到的任何问题，均可以通过拨打我们的热线电话400-668-6834，或者技术支持邮箱tech@selleck.cn，直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题，请给我们留言。

常见问题及建议解决方法

问题 1：
I would like to deliver S1001 via i.p. injection, can you suggest a vehicle solution?
回答：
S1001 ABT-263 (Navitoclax) can be dissolved in 5% DMSO+corn oil at 7mg/ml as a clear solution.
问题 2：
Could you tell me if the catalog number S1001 can go through the hemato-encephalic barrier?
回答：
According to the paper: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223694/, ABT-263 can not cross brain-blood barrier.

Bcl-2 Signaling Pathway Map

Bcl-2 Inhibitors with Unique Features

选择性强的Bcl-2抑制剂

ABT-199 (GDC-0199) : Bcl-2-selective, K_i<0.01 nM.
用于临床的Bcl-2抑制剂

Obatoclax Mesylate (GX15-070) : Phase II for leukemia, lymphoma, myelofibrosis, and mastocytosis.
最新的Bcl-2家族激活剂

BAM7 : Direct and selective activator of proapoptotic Bax with EC50 of 3.3 μM.
经典的Bcl-2抑制剂

ABT-737 : BH3-mimetic inhibitor, Bcl-xL, EC50=78.7 nM; Bcl-2, EC50=30.3 nM; Bcl-w, EC50=197.8 nM.

研究领域

产品类型

定制您的化合物库

Navitoclax (ABT-263)

客户使用Selleck生产的Navitoclax (ABT-263)发表文献222篇：

产品安全说明书

Bcl-2抑制剂选择性比较

生物活性

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

参考文献

溶解度 (25°C)

化学数据 Download Navitoclax (ABT-263) SDF

动物体内配方计算器 (澄清溶液)

计算器

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

稀释计算器

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

连续稀释计算器方程

连续稀释

计算结果

分子量计算器

总分子量：g/mol

摩尔浓度计算器

技术支持

常见问题及建议解决方法

Bcl-2 Signaling Pathway Map

Bcl-2 Inhibitors with Unique Features

相关Bcl-2产品