WH-4-023

For research use only. Not for use in humans.

目录号:S7565 别名: KIN001-112, KIN112

WH-4-023 Chemical Structure

CAS No. 837422-57-8

WH-4-023 (KIN001-112, KIN112) 是一种有效的,口服具有活性的Lck/Src抑制剂,无细胞试验中IC50分别为2 nM 和 6 nM。对p38α和KDR的选择性低300倍以上,还能有效抑制SIK(对SIK1、2、3的IC50分别为10、22、60 nM)。

规格 价格 库存 购买数量  
RMB 1221.65 现货
RMB 3880.83 现货
RMB 8150.52 现货
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客户使用Selleck生产的WH-4-023发表文献7篇:

客户使用该产品的1个实验数据:

  • (G-I) WB analysis of total LCK, LCK Y505, and Src Y416 expression in ALL-SIL, CCRF-CEM, and TALL-1. Cells were treated with DMSO only (Ctrl), dasatinib, bosutinib, nintedanib, or WH-4-023 overnight at the compound concentrations corresponding to the GI50 at 48 hr. Bos, bosutinib; Das, dasatinib; Nint, nintedanib; WH, WH-4-023.

    Blood, 2017, 130(25):2750-2761. WH-4-023 purchased from Selleck.

产品安全说明书

Src抑制剂选择性比较

生物活性

产品描述 WH-4-023 (KIN001-112, KIN112) 是一种有效的,口服具有活性的Lck/Src抑制剂,无细胞试验中IC50分别为2 nM 和 6 nM。对p38α和KDR的选择性低300倍以上,还能有效抑制SIK(对SIK1、2、3的IC50分别为10、22、60 nM)。
靶点
Lck [1]
(Cell-free assay)
Src [1]
(Cell-free assay)
2 nM 6 nM
体外研究

WH-4-023对p38 和 KDR显示出低活性。[1]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
human EM-2 cell NGLaPZVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWXJcohq[mm2aX;uJI9nKGi3bXHuJGVONTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Lkmx[U0xQCEQvF2= MV3TRW5ITVJ?
human LAMA-84 cell MmjYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnHVTY5pcWKrdHnvckBw\iCqdX3hckBNSU2DLUi0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{44QGVvME[g{txO MnXKV2FPT0WU
human EoL-1-cell cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGfPU3NKdmirYnn0bY9vKG:oIHj1cYFvKEWxTD2xMYNmdGxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD17LkWx[U0xPiEQvF2= MnL0V2FPT0WU
human MEG-01 cell NWrLOpN5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXfJcohq[mm2aX;uJI9nKGi3bXHuJG1GTy1yMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuOlNmNTB3IN88US=> NGXPNIlUSU6JRWK=
human CTV-1 cell NYPrXWxVT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MU\Jcohq[mm2aX;uJI9nKGi3bXHuJGNVXi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz6xPIUuODVizszN NGDnXGlUSU6JRWK=
human BL-70 cell M2XwPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M13HXWlvcGmkaYTpc44hd2ZiaIXtZY4hSkxvN{CgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Mlcz\S1yNTFOwG0> MXjTRW5ITVJ?
human K-562 cell NHmxclJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWfXT2VFUW6qaXLpeIlwdiCxZjDoeY1idiCNLUW2NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODByMU[yJO69VQ>? MnXaV2FPT0WU
human BV-173 cell NWnyZm1YT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVXzepBNUW6qaXLpeIlwdiCxZjDoeY1idiCEVj2xO|Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjByMEWxOEDPxE1? MljaV2FPT0WU
human DOHH-2 cell MYLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYHJPG41UW6qaXLpeIlwdiCxZjDoeY1idiCGT1jIMVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjByMEW5O{DPxE1? NEfz[GhUSU6JRWK=
human A704 cell MkXWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEXRZmNKdmirYnn0bY9vKG:oIHj1cYFvKEF5MESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlAxOTJ5IN88US=> M4rPOnNCVkeHUh?=
human NCI-SNU-16 cell M2fjcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{fwO2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLWPOWU0yPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMEG1O|Ih|ryP NHzFNlVUSU6JRWK=
human LC-2-ad cell M4rm[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NF\IXIlKdmirYnn0bY9vKG:oIHj1cYFvKEyFLUKtZYQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB{MEOzJO69VQ>? NUC3PZh5W0GQR1XS
human LB2518-MEL cell M4L0[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3fvdGlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{NUG4MW1GVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMES2Olch|ryP MnP5V2FPT0WU
human D-336MG cell NXfLSnU4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVPJcohq[mm2aX;uJI9nKGi3bXHuJGQuOzN4TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlA1PjhzIN88US=> M2TPRnNCVkeHUh?=
human LB996-RCC cell NUPMZmd1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWq4b2NmUW6qaXLpeIlwdiCxZjDoeY1idiCOQkm5Ok1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkC1OlY5KM7:TR?= NHXtXIZUSU6JRWK=
human Becker cell M1HLe2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2\1fWlvcGmkaYTpc44hd2ZiaIXtZY4hSmWla3XyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xPjN6MTFOwG0> MWjTRW5ITVJ?
human LB1047-RCC cell NWniXFN1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1fDfWlvcGmkaYTpc44hd2ZiaIXtZY4hVEJzMES3MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMEe1PVIh|ryP MkT1V2FPT0WU
human KS-1 cell Mo\VS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2LlOGlvcGmkaYTpc44hd2ZiaIXtZY4hU1NvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFc4PThizszN NGfYOWhUSU6JRWK=
human MPP-89 cell MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFLxO|BKdmirYnn0bY9vKG:oIHj1cYFvKE2SUD24PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODh{Mkmg{txO M3vWOnNCVkeHUh?=
human RXF393 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlntTY5pcWKrdHnvckBw\iCqdX3hckBTYEZ|OUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlExPjN|IN88US=> M2nPXHNCVkeHUh?=
LB831-BLC cell MoTxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYP3TY1rUW6qaXLpeIlwdiCxZjDoeY1idiCOQkizNU1DVENiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkGyO|E2KM7:TR?= MkX1V2FPT0WU
HUTU-80 cell M4niWGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXrWeZZ5UW6qaXLpeIlwdiCxZjDoeY1idiCKVWTVMVgxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5zN{WyPUDPxE1? Mon6V2FPT0WU
A498 cell MWjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3vXSmlvcGmkaYTpc44hd2ZiaIXtZY4hSTR7ODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNVg6PDVizszN NYDheHV1W0GQR1XS
MZ1-PC cell MkexS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVXJcohq[mm2aX;uJI9nKGi3bXHuJG1bOS2SQzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNlI4OTZizszN M4\hcXNCVkeHUh?=
TE-8 cell M3;6cWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmHuTY5pcWKrdHnvckBw\iCqdX3hckBVTS16IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6yN|kzPCEQvF2= M3;COXNCVkeHUh?=
MFH-ino cell  NG\XTFJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlrqTY5pcWKrdHnvckBw\iCqdX3hckBOTkhvaX7vJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4zOzl{NTFOwG0> NEXt[GVUSU6JRWK=
TE-15 cell MnnLS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGfTVIJKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUG1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4zPDJ5NjFOwG0> NFXhSmtUSU6JRWK=
NTERA-S-cl-D1 cell MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUDpfolpUW6qaXLpeIlwdiCxZjDoeY1idiCQVFXSRU1UNWOuLVSxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4zQDh3NTFOwG0> MYnTRW5ITVJ?
COLO-829 cell Mnj0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkPlTY5pcWKrdHnvckBw\iCqdX3hckBEV0yRLUiyPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzF{MUKg{txO NXywPIN5W0GQR1XS
SW684 cell MlfjS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3Tz[GlvcGmkaYTpc44hd2ZiaIXtZY4hW1d4OESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlMzPTh6IN88US=> NILo[mdUSU6JRWK=
OS-RC-2 cell M4\LSWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUPJcohq[mm2aX;uJI9nKGi3bXHuJG9UNVKFLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlM2ODFzIN88US=> NVnXPINxW0GQR1XS
IST-MES1 cell MkjmS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoHDTY5pcWKrdHnvckBw\iCqdX3hckBKW1RvTVXTNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzV5MkOg{txO MY\TRW5ITVJ?
SNB75 cell NGj0b4lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFLSXVJKdmirYnn0bY9vKG:oIHj1cYFvKFOQQke1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4{PTd5NDFOwG0> MX3TRW5ITVJ?
SW954 cell MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFriUGRKdmirYnn0bY9vKG:oIHj1cYFvKFOZOUW0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4{PzF4MzFOwG0> NU\aO413W0GQR1XS
RCC10RGB cell M1;VXWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NX;zbIN6UW6qaXLpeIlwdiCxZjDoeY1idiCUQ1OxNHJISiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwNEK2N|Eh|ryP NVfrVG1DW0GQR1XS
VA-ES-BJ cell M4TzXmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUi2NlFRUW6qaXLpeIlwdiCxZjDoeY1idiCYQT3FV{1DUiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwNE[yOkDPxE1? Ml62V2FPT0WU
NCI-H1648 cell NVf2XJFyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3u5[WlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOlQ5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC53MUW4NkDPxE1? NHrXe4RUSU6JRWK=
PF-382 cell M2\ubWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MonaTY5pcWKrdHnvckBw\iCqdX3hckBRTi1|OEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlcxPzZ|IN88US=> MWPTRW5ITVJ?
human Daudi cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MX\Jcohq[mm2aX;uJI9nKGi3bXHuJGRifWSrIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD63NVQyOSEQvF2= NEnndW1USU6JRWK=
SW982 cell NYnsVVR3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NF7ydZRKdmirYnn0bY9vKG:oIHj1cYFvKFOZOUiyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE45PThzOTFOwG0> NFm2V5RUSU6JRWK=
SW872 cell MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2O4[WlvcGmkaYTpc44hd2ZiaIXtZY4hW1d6N{KgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlg3PDV6IN88US=> NIHNTXFUSU6JRWK=
TE-12 cell NHPUZmNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUHsN25iUW6qaXLpeIlwdiCxZjDoeY1idiCWRT2xNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvQDh6M{Gg{txO NYnWemlDW0GQR1XS
human HOP-62 cell M2jVNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYrLXHNoUW6qaXLpeIlwdiCxZjDoeY1idiCKT2CtOlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjlzNUm5JO69VQ>? M3XYbnNCVkeHUh?=
human NOS-1 cell NWD4blhoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHTyZ|VKdmirYnn0bY9vKG:oIHj1cYFvKE6RUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE46PTB2NTFOwG0> NEnidpRUSU6JRWK=
human BL-41 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M121WWlvcGmkaYTpc44hd2ZiaIXtZY4hSkxvNEGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlAxODF|IN88US=> MYjTRW5ITVJ?
human TGBC24TKB cell MkfkS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3vjbmlvcGmkaYTpc44hd2ZiaIXtZY4hXEeEQ{K0WGtDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS5yM{izNUDPxE1? MmTkV2FPT0WU
human KGN cell NGTSRXpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXjJcohq[mm2aX;uJI9nKGi3bXHuJGtIViClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwMEWyNUDPxE1? M2rGbHNCVkeHUh?=
human TK10 cell NIXj[WRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2P0U2lvcGmkaYTpc44hd2ZiaIXtZY4hXEtzMDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNFg1OThizszN MmnSV2FPT0WU
human GB-1 cell M{T4O2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXjJcohq[mm2aX;uJI9nKGi3bXHuJGdDNTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkG2NFY1KM7:TR?= NEW0Z4tUSU6JRWK=
human GCIY cell MXvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX7iVHZkUW6qaXLpeIlwdiCxZjDoeY1idiCJQ1nZJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4zOzBzIN88US=> M3jORnNCVkeHUh?=
human LXF-289 cell NHfjUIZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlzYTY5pcWKrdHnvckBw\iCqdX3hckBNYEZvMki5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4zPzJ3NjFOwG0> NXvnPWppW0GQR1XS
RL95-2 cell MWHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmrCTY5pcWKrdHnvckBw\iCqdX3hckBTVDl3LUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlMzPDN4IN88US=> NFLmZ5lUSU6JRWK=
human SW962 cell MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGXacGZKdmirYnn0bY9vKG:oIHj1cYFvKFOZOU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4{Ozd2MjFOwG0> M33uVHNCVkeHUh?=
human HT-144 cell MkDXS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{DpeWlvcGmkaYTpc44hd2ZiaIXtZY4hUFRvMUS0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU41PDVzNzFOoI0> NWiyeFdGW0GQR1XS
human IST-SL2 cell MnTGS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4DFdWlvcGmkaYTpc44hd2ZiaIXtZY4hUVOWLWPMNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvPDd2MkGg{txO M4HPSHNCVkeHUh?=
human NB6 cell NF;uRndIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MojpTY5pcWKrdHnvckBw\iCqdX3hckBPSjZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLk[5Olk5KM7:TR?= NXLPfplIW0GQR1XS
human SF126 cell MlnrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NV\GenFqUW6qaXLpeIlwdiCxZjDoeY1idiCVRkGyOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvPzNzN{ig{txO NHTjcopUSU6JRWK=
human BOKU cell MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Ml;nTY5pcWKrdHnvckBw\iCqdX3hckBDV0uXIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT64NFUzPyEQvF2= MmfaV2FPT0WU
human BB30-HNC cell NELIOGtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3v2VmlvcGmkaYTpc44hd2ZiaIXtZY4hSkJ|MD3IUmMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjh3NEeyJO69VQ>? NGjyVlFUSU6JRWK=
human KLE cell MoWxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWLvfVdvUW6qaXLpeIlwdiCxZjDoeY1idiCNTFWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlg3OjN{IN88US=> NYjoV5FWW0GQR1XS
human MLMA cell NF7oOIZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3zxUGlvcGmkaYTpc44hd2ZiaIXtZY4hVUyPQTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuPVI{OSEQvF2= NGXEWmlUSU6JRWK=
human KINGS-1 cell M4XlUWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWHZbndQUW6qaXLpeIlwdiCxZjDoeY1idiCNSV7HV{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS57Nki5O{DPxE1? NYHBcI1yW0GQR1XS
human ES6 cell NGnwO3JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXPpUWFbUW6qaXLpeIlwdiCxZjDoeY1idiCHU{[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlA2PDBzIN88US=> M4PMbXNCVkeHUh?=
human SH-4 cell NHXYSHJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF3OepJKdmirYnn0bY9vKG:oIHj1cYFvKFOKLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlEzODV3IN88US=> M4XNNHNCVkeHUh?=
human D-263MG cell M3;y[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmTxTY5pcWKrdHnvckBw\iCqdX3hckBFNTJ4M13HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4zQDh3MzFOwG0> M2rHR3NCVkeHUh?=
human SF268 cell M2f6[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MoflTY5pcWKrdHnvckBw\iCqdX3hckBUTjJ4ODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuOFg3QDJizszN MnTyV2FPT0WU
human NB17 cell Mo[xS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXnhb3lLUW6qaXLpeIlwdiCxZjDoeY1idiCQQkG3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk43Ojh5NTFOwG0> NUTxe5lIW0GQR1XS
human DMS-114 cell NETCdopIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHfHXHdKdmirYnn0bY9vKG:oIHj1cYFvKESPUz2xNVQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjd7MEKyJO69VQ>? M1;yW3NCVkeHUh?=
MC116 cell NVX5Z2VoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NX3UXHBlUW6qaXLpeIlwdiCxZjDoeY1idiCPQ{GxOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvQDV5MESg{txO NHXVbZNUSU6JRWK=
human NCI-H747 cell M3;ZeWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWDJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KN{S3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OU44PDF3OTFOwG0> MlPUV2FPT0WU
human A388 cell NGDxVJlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXPoXVdZUW6qaXLpeIlwdiCxZjDoeY1idiCDM{i4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVQvPjd3ODFOwG0> MVzTRW5ITVJ?

... Click to View More Cell Line Experimental Data

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

溶解度 (25°C)

体外 DMSO 12 mg/mL warmed (21.1 mM)
Ethanol 6 mg/mL warmed (10.55 mM)
Water Insoluble
体内 从左到右依次将纯溶剂加入产品,现配现用(数据来自Selleck实验检测而非文献):
5% DMSO+30% PEG 300+5% Tween 80+ddH2O
1mg/mL

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 568.67
化学式

C32H36N6O4

CAS号 837422-57-8
储存条件 粉状
溶于溶剂
别名 KIN001-112, KIN112

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系Selleck为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % ddH2O
计算重置

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

技术支持

在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-668-6834,或者技术支持邮箱tech@selleck.cn,直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题,请给我们留言。

  • * 必填项

Src Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID