WH-4-023

For research use only. Not for use in humans.

目录号:S7565 别名: KIN001-112, KIN112

WH-4-023 Chemical Structure

CAS No. 837422-57-8

WH-4-023 (KIN001-112, KIN112) 是一种有效的,口服具有活性的Lck/Src抑制剂,无细胞试验中IC50分别为2 nM 和 6 nM。对p38α和KDR的选择性低300倍以上,还能有效抑制SIK(对SIK1、2、3的IC50分别为10、22、60 nM)。

规格 价格 库存 购买数量  
RMB 1221.65 现货
RMB 3880.83 现货
RMB 8150.52 现货
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客户使用Selleck生产的WH-4-023发表文献7篇:

客户使用该产品的1个实验数据:

  • (G-I) WB analysis of total LCK, LCK Y505, and Src Y416 expression in ALL-SIL, CCRF-CEM, and TALL-1. Cells were treated with DMSO only (Ctrl), dasatinib, bosutinib, nintedanib, or WH-4-023 overnight at the compound concentrations corresponding to the GI50 at 48 hr. Bos, bosutinib; Das, dasatinib; Nint, nintedanib; WH, WH-4-023.

    Blood, 2017, 130(25):2750-2761. WH-4-023 purchased from Selleck.

产品安全说明书

Src抑制剂选择性比较

生物活性

产品描述 WH-4-023 (KIN001-112, KIN112) 是一种有效的,口服具有活性的Lck/Src抑制剂,无细胞试验中IC50分别为2 nM 和 6 nM。对p38α和KDR的选择性低300倍以上,还能有效抑制SIK(对SIK1、2、3的IC50分别为10、22、60 nM)。
靶点
Lck [1]
(Cell-free assay)
Src [1]
(Cell-free assay)
2 nM 6 nM
体外研究

WH-4-023对p38 和 KDR显示出低活性。[1]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
human EM-2 cell NUDkd41TT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkTrTY5pcWKrdHnvckBw\iCqdX3hckBGVS1{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz65NYUuODhizszN NYKxUGlTW0GQR1XS
human LAMA-84 cell MnTxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUnJcohq[mm2aX;uJI9nKGi3bXHuJGxCVUFvOESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlc5\S1yNjFOwG0> NF;BNo1USU6JRWK=
human EoL-1-cell cell NWHUNoFmT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFLDZmVKdmirYnn0bY9vKG:oIHj1cYFvKEWxTD2xMYNmdGxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD17LkWx[U0xPiEQvF2= NGnZbZVUSU6JRWK=
human MEG-01 cell M33xUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3LqUmlvcGmkaYTpc44hd2ZiaIXtZY4hVUWJLUCxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU43O2VvMEWg{txO MoLpV2FPT0WU
human CTV-1 cell MWHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MV\Jcohq[mm2aX;uJI9nKGi3bXHuJGNVXi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz6xPIUuODVizszN M3LqWHNCVkeHUh?=
human BL-70 cell MojYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHrHPJlKdmirYnn0bY9vKG:oIHj1cYFvKEKOLUewJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE44OmVvMEWg{txO MYnTRW5ITVJ?
human K-562 cell NI\2WXRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXHGUHd1UW6qaXLpeIlwdiCxZjDoeY1idiCNLUW2NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODByMU[yJO69VQ>? MWXTRW5ITVJ?
human BV-173 cell NV7qSpI2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{XXT2lvcGmkaYTpc44hd2ZiaIXtZY4hSlZvMUezJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xODB3MUSg{txO NVvGXJlOW0GQR1XS
human DOHH-2 cell MYfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWPKT3FlUW6qaXLpeIlwdiCxZjDoeY1idiCGT1jIMVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjByMEW5O{DPxE1? MXPTRW5ITVJ?
human A704 cell MnzHS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVjX[od2UW6qaXLpeIlwdiCxZjDoeY1idiCDN{C0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xODF{NzFOwG0> MWTTRW5ITVJ?
human NCI-SNU-16 cell Mmr4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3XLfGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLWPOWU0yPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMEG1O|Ih|ryP MlO0V2FPT0WU
human LC-2-ad cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWn2R45yUW6qaXLpeIlwdiCxZjDoeY1idiCOQz2yMYFlKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yMkCzN{DPxE1? MoXzV2FPT0WU
human LB2518-MEL cell NE\1SXRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXviXIR{UW6qaXLpeIlwdiCxZjDoeY1idiCOQkK1NVguVUWOIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6wOFY3PyEQvF2= NWnFc5lTW0GQR1XS
human D-336MG cell NIHyT2pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2DhZmlvcGmkaYTpc44hd2ZiaIXtZY4hTC1|M{\NS{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODR4OEGg{txO NYTqe4xXW0GQR1XS
human LB996-RCC cell Mn3iS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4\uTWlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ7OU[tVmNEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yNU[2PEDPxE1? MlPpV2FPT0WU
human Becker cell NIru[Y5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUS3XFBmUW6qaXLpeIlwdiCxZjDoeY1idiCEZXPr[ZIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB4M{ixJO69VQ>? M1nxfnNCVkeHUh?=
human LB1047-RCC cell NFTpO5JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MV7Jcohq[mm2aX;uJI9nKGi3bXHuJGxDOTB2Nz3SR2Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB5NUmyJO69VQ>? Mlv2V2FPT0WU
human KS-1 cell NX\G[HVFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVPsWIM{UW6qaXLpeIlwdiCxZjDoeY1idiCNUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xPzd3ODFOwG0> M4fPVHNCVkeHUh?=
human MPP-89 cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4PETWlvcGmkaYTpc44hd2ZiaIXtZY4hVVCSLUi5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xQDJ{OTFOwG0> NWnBbXNvW0GQR1XS
human RXF393 cell M{W3TWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Ml7PTY5pcWKrdHnvckBw\iCqdX3hckBTYEZ|OUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlExPjN|IN88US=> NIL1VJBUSU6JRWK=
LB831-BLC cell NFXqSmJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmixTY5pcWKrdHnvckBw\iCqdX3hckBNSjh|MT3CUGMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjF{N{G1JO69VQ>? MYDTRW5ITVJ?
HUTU-80 cell M1foTmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXjFfpJDUW6qaXLpeIlwdiCxZjDoeY1idiCKVWTVMVgxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5zN{WyPUDPxE1? Ml\vV2FPT0WU
A498 cell NYe3UXFoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUfJcohq[mm2aX;uJI9nKGi3bXHuJGE1QThiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkG4PVQ2KM7:TR?= M{jRV3NCVkeHUh?=
MZ1-PC cell MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Ml;KTY5pcWKrdHnvckBw\iCqdX3hckBOYjFvUFOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlIzPzF4IN88US=> NX7yZ4tSW0GQR1XS
TE-8 cell NULU[W5[T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXP5OXhqUW6qaXLpeIlwdiCxZjDoeY1idiCWRT24JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4zOzl{NDFOwG0> MV\TRW5ITVJ?
MFH-ino cell  M2rNd2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmewTY5pcWKrdHnvckBw\iCqdX3hckBOTkhvaX7vJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4zOzl{NTFOwG0> NVq1PHg4W0GQR1XS
TE-15 cell M4D4PWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUnuNZNQUW6qaXLpeIlwdiCxZjDoeY1idiCWRT2xOUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOjR{N{[g{txO NYnIbIs5W0GQR1XS
NTERA-S-cl-D1 cell Mn\1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mon3TY5pcWKrdHnvckBw\iCqdX3hckBPXEWUQT3TMYNtNURzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6yPFg2PSEQvF2= M3\GOnNCVkeHUh?=
COLO-829 cell NW\yVZppT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MljSTY5pcWKrdHnvckBw\iCqdX3hckBEV0yRLUiyPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzF{MUKg{txO MV\TRW5ITVJ?
SW684 cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1fvOmlvcGmkaYTpc44hd2ZiaIXtZY4hW1d4OESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlMzPTh6IN88US=> MUXTRW5ITVJ?
OS-RC-2 cell MkXTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{n1cmlvcGmkaYTpc44hd2ZiaIXtZY4hV1NvUlOtNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzVyMUGg{txO Mom1V2FPT0WU
IST-MES1 cell MoHBS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUDDZnNjUW6qaXLpeIlwdiCxZjDoeY1idiCLU2StUWVUOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwM{W3NlMh|ryP MVnTRW5ITVJ?
SNB75 cell Mn;lS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4TuOWlvcGmkaYTpc44hd2ZiaIXtZY4hW06EN{WgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlM2Pzd2IN88US=> MU\TRW5ITVJ?
SW954 cell M2iyPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnnqTY5pcWKrdHnvckBw\iCqdX3hckBUXzl3NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuN|cyPjNizszN Ml;BV2FPT0WU
RCC10RGB cell NXrERXhDT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYrJcohq[mm2aX;uJI9nKGi3bXHuJHJESzFyUlfCJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE41OjZ|MTFOwG0> NH3JZ5JUSU6JRWK=
VA-ES-BJ cell MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{fJO2lvcGmkaYTpc44hd2ZiaIXtZY4hXkFvRWOtRmoh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjR4Mk[g{txO NHjFbm9USU6JRWK=
NCI-H1648 cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnfFTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG2OFgh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjVzNUiyJO69VQ>? M1PQUHNCVkeHUh?=
PF-382 cell MojXS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M37Jc2lvcGmkaYTpc44hd2ZiaIXtZY4hWEZvM{iyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE44ODd4MzFOwG0> M2m2XXNCVkeHUh?=
human Daudi cell Mn\qS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3;LemlvcGmkaYTpc44hd2ZiaIXtZY4hTGG3ZHmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlcyPDFzIN88US=> MWDTRW5ITVJ?
SW982 cell NHzZUopIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mn:zTY5pcWKrdHnvckBw\iCqdX3hckBUXzl6MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuPFU5OTlizszN NY\4fnBPW0GQR1XS
SW872 cell MljES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWnJcohq[mm2aX;uJI9nKGi3bXHuJHNYQDd{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD64OlQ2QCEQvF2= MV;TRW5ITVJ?
TE-12 cell NETnc5RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHnqRmtKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUGyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE45QDh|MTFOwG0> M2LoenNCVkeHUh?=
human HOP-62 cell MVHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1nqemlvcGmkaYTpc44hd2ZiaIXtZY4hUE:SLU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE46OTV7OTFOwG0> NH7zRpdUSU6JRWK=
human NOS-1 cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{HRfmlvcGmkaYTpc44hd2ZiaIXtZY4hVk:VLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlk2ODR3IN88US=> MlLjV2FPT0WU
human BL-41 cell NIfDb|VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXTPfm1tUW6qaXLpeIlwdiCxZjDoeY1idiCETD20NUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvODByMUOg{txO MlvXV2FPT0WU
human TGBC24TKB cell MmTBS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MV3Jcohq[mm2aX;uJI9nKGi3bXHuJHRISkN{NGTLRkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvODN6M{Gg{txO M4rv[XNCVkeHUh?=
human KGN cell M37OU2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUfJcohq[mm2aX;uJI9nKGi3bXHuJGtIViClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwMEWyNUDPxE1? MkDjV2FPT0WU
human TK10 cell M121dWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MoO5TY5pcWKrdHnvckBw\iCqdX3hckBVUzFyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6wPFQyQCEQvF2= M4jYTnNCVkeHUh?=
human GB-1 cell NXmzWZYxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVvDc2xMUW6qaXLpeIlwdiCxZjDoeY1idiCJQj2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4yPjB4NDFOwG0> M3rHPHNCVkeHUh?=
human GCIY cell MlzXS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mn\nTY5pcWKrdHnvckBw\iCqdX3hckBIS0m\IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6yN|AyKM7:TR?= MWrTRW5ITVJ?
human LXF-289 cell NXnQRXkxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2W4fGlvcGmkaYTpc44hd2ZiaIXtZY4hVFiILUK4PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvOjd{NU[g{txO NHLWPHRUSU6JRWK=
RL95-2 cell M1;rdGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXjJcohq[mm2aX;uJI9nKGi3bXHuJHJNQTVvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuN|I1OzZizszN NFjQWpFUSU6JRWK=
human SW962 cell M3P6Smdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWCyOFBlUW6qaXLpeIlwdiCxZjDoeY1idiCVV{m2NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvOzN5NEKg{txO NVO3eWhSW0GQR1XS
human HT-144 cell NETUSnFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{nobGlvcGmkaYTpc44hd2ZiaIXtZY4hUFRvMUS0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU41PDVzNzFOoI0> M3HobnNCVkeHUh?=
human IST-SL2 cell M4WyOGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mon6TY5pcWKrdHnvckBw\iCqdX3hckBKW1RvU1yyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU41PzR{MTFOwG0> MVvTRW5ITVJ?
human NB6 cell MX3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlX5TY5pcWKrdHnvckBw\iCqdX3hckBPSjZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLk[5Olk5KM7:TR?= MWPTRW5ITVJ?
human SF126 cell M1LKSGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnfnTY5pcWKrdHnvckBw\iCqdX3hckBUTjF{NjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuO|MyPzhizszN NXLHR4RSW0GQR1XS
human BOKU cell M1;1SWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIG5NoZKdmirYnn0bY9vKG:oIHj1cYFvKEKRS2WgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlgxPTJ5IN88US=> MXXTRW5ITVJ?
human BB30-HNC cell Mni0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmrRTY5pcWKrdHnvckBw\iCqdX3hckBDSjNyLVjOR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvQDV2N{Kg{txO MlPDV2FPT0WU
human KLE cell M1;iNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHnMcHhKdmirYnn0bY9vKG:oIHj1cYFvKEuORTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuPFYzOzJizszN NGXwemlUSU6JRWK=
human MLMA cell MY\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEjqZ|FKdmirYnn0bY9vKG:oIHj1cYFvKE2OTVGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlkzOzFizszN M2\1UnNCVkeHUh?=
human KINGS-1 cell M2jrOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mlr1TY5pcWKrdHnvckBw\iCqdX3hckBMUU6JUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU46Pjh7NzFOwG0> NITBc3JUSU6JRWK=
human ES6 cell NYjZOpdnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2TjcGlvcGmkaYTpc44hd2ZiaIXtZY4hTVN4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj6wOVQxOSEQvF2= NXjaPJBJW0GQR1XS
human SH-4 cell M3e2WWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4DuPGlvcGmkaYTpc44hd2ZiaIXtZY4hW0hvNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuNVIxPTVizszN M{izOnNCVkeHUh?=
human D-263MG cell MlqxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MX;Jcohq[mm2aX;uJI9nKGi3bXHuJGQuOjZ|TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlI5QDV|IN88US=> NFTnN|FUSU6JRWK=
human SF268 cell MV7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NInBR|dKdmirYnn0bY9vKG:oIHj1cYFvKFOIMk[4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk41QDZ6MjFOwG0> MWDTRW5ITVJ?
human NB17 cell NIDZeGpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYTJcohq[mm2aX;uJI9nKGi3bXHuJG5DOTdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{Lk[yPFc2KM7:TR?= M3;wZ3NCVkeHUh?=
human DMS-114 cell NWDH[|hPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEiyXZZKdmirYnn0bY9vKG:oIHj1cYFvKESPUz2xNVQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjd7MEKyJO69VQ>? MkmyV2FPT0WU
MC116 cell M1HXSGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MULJcohq[mm2aX;uJI9nKGi3bXHuJG1EOTF4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj64OVcxPCEQvF2= NXy4fGpTW0GQR1XS
human NCI-H747 cell MljiS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NF:wdYhKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IO|Q4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PS55NEG1PUDPxE1? NXzQTod3W0GQR1XS
human A388 cell MmTwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWfTVY1GUW6qaXLpeIlwdiCxZjDoeY1idiCDM{i4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVQvPjd3ODFOwG0> MXjTRW5ITVJ?

... Click to View More Cell Line Experimental Data

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

溶解度 (25°C)

体外 DMSO 12 mg/mL warmed (21.1 mM)
Ethanol 6 mg/mL warmed (10.55 mM)
Water Insoluble
体内 从左到右依次将纯溶剂加入产品,现配现用(数据来自Selleck实验检测而非文献):
5% DMSO+30% PEG 300+5% Tween 80+ddH2O
1mg/mL

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 568.67
化学式

C32H36N6O4

CAS号 837422-57-8
储存条件 粉状
溶于溶剂
别名 KIN001-112, KIN112

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系Selleck为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % ddH2O
计算重置

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

技术支持

在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-668-6834,或者技术支持邮箱tech@selleck.cn,直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题,请给我们留言。

  • * 必填项

Src Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID