Z-VAD-FMK

For research use only. Not for use in humans.

目录号:S7023

Z-VAD-FMK Chemical Structure

CAS No. 187389-52-2

Z-VAD-FMK是一种细胞渗透性的,不可逆泛caspase抑制剂,在THP.1 和 Jurkat T细胞中阻断细胞凋亡的所有特性。

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RMB 3841.92 现货

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客户使用Selleck生产的Z-VAD-FMK发表文献581篇:

产品安全说明书

Caspase抑制剂选择性比较

生物活性

产品描述 Z-VAD-FMK是一种细胞渗透性的,不可逆泛caspase抑制剂,在THP.1 和 Jurkat T细胞中阻断细胞凋亡的所有特性。
特性 Z-VAD-FMK是研究细胞凋亡的一种关键化合物。
靶点
Pan-caspase [1]
(THP.1, Jurkat T-cells)
体外研究

Z-VAD-FMK(10 mM)作用于THP.1细胞,抑制细胞凋亡。Z-VAD-FMK(10 μM)作用于THP.1细胞裂解液,抑制PARP蛋白酶活性的激活。Z-VAD-FMK(10 mM)作用于完整THP.1和 Jurkat细胞,抑制CPP32加工。[1]Z-VAD-FMK(50 μM)与Camptothecin共处理HL60细胞,废除Camptothecin处理的细胞凋亡形态。Z-VAD-FMK(50 μM)作用于HL60细胞,抑制Camptothecin诱导的DNA分裂。[2]Z-VAD-FMK (50 μM)作用于S2细胞,提高转染细胞的生存百分数从26%提高到63%。[3]Z-VAD-FMK(>100 μM)作用于人类嗜中性粒细胞,增强TNFα-诱导的中性粒细胞凋亡,较低浓度(1-30 μM)时完全抑制TNFα刺激的细胞凋亡。[4]Z-VAD-FMK (10 mM) 作用于早期角膜基质细胞,抑制细胞凋亡。[5]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
GC1a M2K2OmFxd3C2b4Ppd{BCe3OjeR?= NGfLPZA2OM7:TR?= M3TLcFI1cA>? MnnhbY5lcWOjdHXzJIEheHKxdHXjeIl3\SCnZn\lZ5Qh[WejaX7zeEBmfG:yb4Pp[IU> MYSyOlE3QTB5NR?=
HGL5 MXjBdI9xfG:|aYOgRZN{[Xl? MV[1NO69VQ>? M4rsW|I1cA>? M4HYXolv\GmlYYTld{BiKHC{b4TlZ5RqfmViZX\m[YN1KGGpYXnud5Qh\XSxcH;zbYRm NX;abGtvOjZzNkmwO|U>
HepG2 NIDoNlFCeG:ydH;zbZMhSXO|YYm= M1WyWFIx|ryP MkPVNYg> MoXCZZR1\W63YYTl[EB1cGViYYDvdJRwfGmlIHnu[JVkfGmxbjDv[kBKUUlvMUFCpC=> MX6yOlE3PDd7NR?=
BEL-7402 M4DFNWFxd3C2b4Ppd{BCe3OjeR?= M{fISFIx|ryP MlqxNYg> MYLheJRmdnWjdHXkJJRp\SCjcH;weI91cWNiaX7keYN1cW:wIH;mJGlKUS1zMNMg MnzRNlYyPjR5OUW=
CEF MlnMT4lv[XOnIFHzd4F6 NIrSb3oxNDN|LE[3MFExOM7:TR?= NVfaSJZjOTWvaX6= NXzKSWFx\G:5bj3y[Yd2dGG2ZYOgVHIh\W68eX3lJIFkfGm4aYT5JJRwKDRy78{FJIF1KDFyMN88US=> NFGycW8zPjFyMkOzPS=>
SP2/0 NYL2R3BQSXCxcITvd4l{KEG|c3H5 MYmxNFDPxE1? Moq3NYg> NWHkS3RzTE2VTx?= NGPJbIpjdG:la4OgeIhmKGGyb4D0c5NqeyCxZjDTVFIwOCClZXzsdy=> NFfvXpQzPjB5NEezNi=>
HUVEC-2c NFfQUGlCeG:ydH;zbZMhSXO|YYm= M1X4RlUx|ryP M{jZO|Zp M{XMdIRm[3KnYYPl[EB1cGVib4itUGRNNWmwZIXj[YQh[XW2b4DoZYd6 M{exblI3ODJzN{K5
U1 M1TTSmFxd3C2b4Ppd{BCe3OjeR?= MknVNE0yODEQvF2= NInNeXUzcA>? Moq4doVlfWOnczDkdpVoNWmwZIXj[YQh[XCxcITvd4l{KGGwZDDzeYJ{\XG3ZX70JGhKXi1zIILldIxq[2G2aX;uJIlvKGFiZH;z[U1l\XCnbnTlcpQhdWGwbnXy MVuyOVk5ODl2Mh?=
ACH-2 NH\ne5NCeG:ydH;zbZMhSXO|YYm= NH\yVI8xNTJyMN88US=> M2HZVFJp MWry[YR2[2W|IHTyeYcucW6mdXPl[EBieG:ydH;zbZMh[W6mIIP1ZpNmeXWnboSgTGlXNTFicnXwcIlk[XSrb36gbY4h[SCmb4PlMYRmeGWwZHXueEBu[W6wZYK= NHzxRnczPTl6MEm0Ni=>
U1 NUjGSIhkU2mwYYPlJGF{e2G7 NXzkeVN{OTByzszN MlLLNog> NF2xUJhqdmirYnn0d{Bk[XOyYYPlMVM> M3HzO|I2QThyOUSy
A549/V16 NUnNN4NVSXCxcITvd4l{KEG|c3H5 NInKW4Y2OM7:TR?= NGjUNnYycA>? NXLYTGdpemWycnXzd4V{KFSJL2TNMYlv\HWlZXSgZZBweHSxc3nz MUSyOVk1PjB|Mx?=
SGN M2XrcmFxd3C2b4Ppd{BCe3OjeR?= MWWyNI1O NWfE[Zh1PDiq Ml\rbIF{KG6xIHnu[ox2\W6lZTDvckBCUUZuIHPhcJBicW5iZYjwdoV{e2mxbjDvdkBk\WyuIHHwc5B1d3Orcx?= NVzRcJROOjV6N{S2N|M>
HCT116  M1\SV2Fxd3C2b4Ppd{BCe3OjeR?= NXq4V2ZDPTEQvF2= NHzwTGwzcA>? M2Gy[YlvcGmkaYTzJJRp\SClZXzsJIRm[XSqIHnu[JVk\WRiYomgSGRXWA>? Mn:0NlU5Pjh6MUi=
DTK-SME MmDGRZBweHSxc3nzJGF{e2G7 NIT5d2U2OM7:TR?= NWrRUGpXOmh? MonkSG1UVw>? M1nuNZBienSrYXzsfUBqdmirYnn0d{B1cGViYYDvdJRwe2m|IHnu[JVk\WRiYomgZpVxcX[jY3HpcoU> MkC0NlU5PDN6OUe=
HL-60 NFHmN|ZCeG:ydH;zbZMhSXO|YYm= M{DNU|Ux|ryP MVG0PIg> NFW4TnFz\WS3Y3XzJINmdGxiZHXheIgh[2G3c3XkJIJ6KFONST3JTUB1emWjdH3lcpTDqA>? NYSwOXNmOjV6MkSwOFM>
U937 MWLBdI9xfG:|aYOgRZN{[Xl? MWm1NO69VQ>? MVW0PIg> NWfKRnpYemWmdXPld{Bk\WyuIHTlZZRpKGOjdYPl[EBjgSCVS1mtTWkhfHKnYYTt[Y51yqB? NHTz[oczPTh{NEC0Ny=>
A549 NIXkb2xCeG:ydH;zbZMhSXO|YYm= NXnZcYIxOjBizszN NGXEc3kzPGh? NHe2TWJz\WS3Y3XzJINmdGxiZHXheIgh[2G3c3XkJIJ6KEiIQ2CgeJJm[XSvZX70 Mln3NlU4QTRzNEm=
HeLa Mn\2RZBweHSxc3nzJGF{e2G7 NH7HUXgyOM7:TR?= MoDJOFhp NUnSWJh3\GWlbHnu[ZMhfGinIILheIUhd2ZiYYDvdJRwe2m|IHTyZY1ifGmlYXzsfS=> MVKyOVc4OjV2NR?=
SGC-7901 MW\BdI9xfG:|aYOgRZN{[Xl? NE\FSIQzOMLizszN M4DaNVFp MUfpcohq[mm2czD0bIUh[2WubDDk[YF1cCCrbnT1Z4VlKGK7IH;4ZYxqeGyjdHnu MlHwNlU4PjdyN{[=
MCF-7 MX\BdI9xfG:|aYOgRZN{[Xl? NWjpdXU6OTEQvF2= MX2ybC=> Ml\5bY5pcWKrdIOgeIhmKGOnbHyg[IVifGhiaX7keYNm\CCkeTCzRi=> NUPiUY5YOjV5MkKxNVQ>
A549 NEfvTG5CeG:ydH;zbZMhSXO|YYm= MXmxNEDPxE1? NE\pW3ozPGh? M1rrd2ROW09? M{LQeJBzd22xdHXzJGhDSy22cnXheIVlKEF3NEmgZ4VtdCC|dYL2bZZidCBoIHH0eIVvfWG2ZYOgeIhmKGOuZXH2[YQhWEGUUDDlfJBz\XO|aX;u MkDqNlU3QDN3Nki=
U87 NUn4SoNvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkDSOVDPxE1? M4\ZdFFp NUD6OpE6emWlb4\ldpMh[2WubDDndo94fGhiZoLvcUBVVVpidILlZZRu\W62 MX:yOVY5OTZ4OB?=
Neocortical Neuron NGfDOGdP\XW{b4TvfIlkcXS7IFHzd4F6 NWHmZ|FpOTByzszN MXGxbC=> M1P3U4FvfGGpb37pfoV{KEixaXHtbYRmKEFvSX7keYNm\CCQZYXyc5RwgGmlaYT5 NEj1W3MzPTZ5NUCwNS=>
Primary human placental cytotrophoblasts MYfBdI9xfG:|aYOgRZN{[Xl? M1LKVVMx|ryP NF3JPFQzPGh? MXTEUXNQ NYnyXlZEemW4ZYLz[ZMhfGinIHnubIljcXSrb36gc4YhOTIQsj3IV2QzKGK7IITybYNtd3OjbtMg MYSyOVY1OjV7Mh?=
MM Ml\iRZBweHSxc3nzJGF{e2G7 MXy1NO69VQ>? M2DCZ|IxdWmw NFv1W45x[XK2bImgbY5pcWKrdIOgV2hMNWmwZIXj[YQhKGOnbHyg[IVifGh? M1Xhb|I2PTNyMEm4
DLD1 MXfBdI9xfG:|aYOgRZN{[Xl? NGX2OmgzOMLizszN NGLSVJoycA>? M1zqeZBienSueTDy[ZZmenOnczDj[YxtKGGyb4D0c5NqeyClYYXz[YQh[nliV2PQNS=> MnGzNlU2OjR{NE[=
MDA-MB-231 NHHhe3ZEgXSxdH;4bYNqfHliQYPzZZk> MoD1NVDPxE1? M{\INlFp MkHvZZVodWWwdIOgZ4VtdCCmZXH0bEBi\nSncjDDTHVCKHS{ZXH0cYVvfA>? NIjvdoYzPTV{MUWwNS=>
MKN28 M2LSOGFxd3C2b4Ppd{BCe3OjeR?= NEf0[VIyOM7:TR?= MXuzNI1qdg>? MXvEUXNQ NFXs[2ZqdmirYnn0d{BVVkZvzsGgdIx2eyCFSGitbY5lfWOnZDDhdI9xfG:|aYO= Ml\rNlU2OTN7NkC=
HL-60 NV21OnQ1S3m2b4TvfIlkcXS7IFHzd4F6 MWixNFDPxE1? NYLNT4xUOWh? NESxdVlFVVOR MVJCpIlueHKxdnXzJJZq[WKrbHn0fUBw\iCWQ17Bd{11emWjdHXkJINmdGy| M2LiSFI2PTB{OUOy
AGS MnrRRZBweHSxc3nzJGF{e2G7 M1zhcVEx|ryP M1HDdFFp NWG1e5RDeHKndnXueJMh[3W{Y4XtbY4ucW6mdXPl[EBkdGWjdnHn[UBw\iClYYPwZZNmNTNuID24MEBidmRiLUmgdJJwfGWrboO= NFrZXZozPTR7MkKxOC=>
A549  NVvJdGlDSXCxcITvd4l{KEG|c3H5 MWKxNO69VQ>? NEnMcpUzPGh? M37J[4Jtd2OtczDEUWFUNWmwZIXj[YQh[2ynYY\h[4Uhd2ZiY3HzdIF{\S1|IHHu[EBRSVKSIHHu[EBieG:ydH;0bYMh[2WubDDk[YF1cA>? MWSyOVQ{PDl6OR?=
INS-1 M3T0OmFxd3C2b4Ppd{BCe3OjeR?= MoPpOVDPxE1? NIHqUmU3cA>? M3;UcmROW09? MUnk[YNz\WG|ZYOgeIhmKHC{b4DvdpRqd25ib3[g[YFzdHliYYDvdJRwfGmlIHPlcIx{yqB? M4HrWVI2PDNyOEm3
Primary hepatocytes  NV[0SJRwSXCxcITvd4l{KEG|c3H5 M3fNTFUx|ryP NYj3XVNEOTiq Mnv6bY5pcWKrdIOgZZBweHSxc3nzJI9nKGincHH0c4N6fGW|IHnu[JVk\WRiYomgRYN1KERiYX7kJHRPTi4QsR?= MnPKNlU1ODd3M{i=
L929-A  MWnDfZRwfG:6aXPpeJkhSXO|YYm= NED0bWIzOMLizszN NWqxVVNkOjSq M{XsPIlvcGmkaYTzJHRPTs7zLXnu[JVk\WRiY3XscEBl\WG2aB?= MmDWNlU{QTh3NEC=
L929-N Ml:xR5l1d3SxeHnjbZR6KEG|c3H5 M{XBdFIxyqEQvF2= MVyyOIg> NWHGU|dI\W6qYX7j[ZMh\GWjdHigeoliKGG3dH;jdolv\SCWTldOtUBxem:mdXP0bY9v NIPKPFAzPTN7OEW0NC=>
Cytotoxicity Assay M1jFR2NmdGxiVnnhZoltcXS7IFHzd4F6 NH3Ud2UzOM7:TR?= M4HlXVQ5cA>? M1LmfpBz\X[nboSgUWhOTC2rbnT1Z4VlKGOnbHyg[IVifGh? M1ywN|I2Ozl{MUG2
COS7 M{nuVWtqdmG|ZTDBd5NigQ>? MUOxNO69VQ>? MonzNlRp MVHpcoNz\WG|ZYOgZ4F{eGG|ZTCzM|ch[WO2aY\peIlmew>? M3:xclI2Ozh2MEK1
COS7 MYXBdI9xfG:|aYOgRZN{[Xl? MWWxNO69VQ>? NEL6NoE1QGh? NID2d2Vx[XK2aXHscJkheHKndnXueIVlKE[FMUCxMYlv\HWlZXSgZ4VtdCCmZXH0bC=> NU\QdXpDOjV|OESwNlU>
A375 NHTOdolCeG:ydH;zbZMhSXO|YYm= MmH4N|DPxE1? MWqybC=> MXLwdoV3\W62czD0bIUh\HK3Zz3pcoR2[2WmIGDBVnAh[2ynYY\h[4U> MnjHNlU{PzZzMUW=
A549 M1njeWFxd3C2b4Ppd{BCe3OjeR?= M2DqelUx|ryP NEfLPIYzPGh? MXny[ZZmenOnczDybYJwe2:vZTDibY9o\W6nc3nzJIFv\CCjcH;weI9{cXNiY3H1d4VlKGK7IDDDbIlrd26pZHHu Ml70NlU{PDl5OEG=
A549 Mon3RZBweHSxc3nzJGF{e2G7 M1f1[|IvPS1{Nd88US=> MUSxbC=> NVLj[ohL\GWlcnXhd4V{KHSqZTDwc5B2dGG2aX;uJI9nKGGyb4D0c5Rq[yClZXzsd{Bl\XCnbnSgc44h[2:wY3XueJJifGmxboO= MkXpNlU{PDJ2Mke=
 NBL-W-S  MXjBdI9xfG:|aYOgRZN{[Xl? NEHySI82OM7:TR?= M2H3d|Fp NHTqNHhnfWyueTDy[ZNkfWW|IHPlcIwhfmmjYnnsbZR6KGGodHXyJGdCVlRvNkGgeJJm[XSvZX70 NIC2UlMzPTN{M{KyNi=>
Caki-1  MWPBdI9xfG:|aYOgRZN{[Xl? MXG0NO69VQ>? NXvVWJltPDiq M2TWd5Jm\HWlZYOgeIhmKG63bXLldkBw\iCDbn7lfIlvKFZvcH;zbZRqfmViY3XscJM> MWiyOVI4QTF7MR?=
769-P M1zxcmFxd3C2b4Ppd{BCe3OjeR?= NGO1UFk1OM7:TR?= MlPrOFhp Mn;0doVlfWOnczD0bIUhdnWvYnXyJI9nKEGwbnX4bY4hXi2yb4PpeIl3\SClZXzsdy=> M1jDV|I2Ojd7MUmx
H9c2 NVjNS5JCSXCxcITvd4l{KEG|c3H5 Mki3OVDPxE1? NWXWRZJTOWh? MYLpcohq[mm2czDEU3gucW6mdXPl[EBk[XOyYYPlJFMh[WO2aY\heIlwdiCkdYSgco91KHSqZTDsc5N{KG:oIHPlcIx{ MlXTNlUzQDN6MUm=
K562 Ml[3RZBweHSxc3nzJGF{e2G7 NIrS[3U2OM7:TR?= Ml7mOIg> NW\nfXlUcW6qaXLpeJMhUmGlLVGtbY5lfWOnZDDj[YxtKGGyb4D0c5Nqew>? M2C4VVI2OjRzNkG5
L929 NYPubolISXCxcITvd4l{KEG|c3H5 MnHKNVDPxE1? NV;i[HZTPmh? Ml\XbY5lfWOnczDu[YNzd3C2b4Ppd{B4cXSqIGTOSi=> MYWyOVE6PTZ4MB?=
A549 MXXBdI9xfG:|aYOgRZN{[Xl? MXKxNO69VQ>? MlTkN4g> MmX2doVlfWOnczDj[YxtKGGyb4D0c5NqeyClYYXz[YQh[nliUGHR MYmyOVE3OTZ7OR?=
MCF-7 MUHBdI9xfG:|aYOgRZN{[Xl? MmjoNlDPxE1? MYKybC=> M1fL[YRm[3KnYYPld{BMTFJvc3nSUmEucW6mdXPl[EBieG:ydH;zbZM> NXyyOJR{OjVzOEKyOFA>
OS MUXBdI9xfG:|aYOgRZN{[Xl? MWqyNE81OM7:TR?= MlnvO|Jp MVvpcohq[mm2czDPV{Bk\WyuII\pZYJqdGm2eTDy[YR2[3Srb36gZpkhSzZiY3XyZY1q\GV? MX[yOVE2OjN7OR?=
HUVECs MYPBdI9xfG:|aYOgRZN{[Xl? MVixNO69VQ>? M2CxelJp NWDVbYtOyqCrbnjpZol1eyCjcH;weI9{cXNiYX7kJIZi[2muaYTheIV{KGG3dH;wbIFogSCrbjDESW5XOi2rbn\lZ5Rm\CCKVW\FR5M> M2O0PFI2OTN6N{Cz
EA.hy926 MUXBdI9xfG:|aYOgRZN{[Xl? MkC5NVDPxE1? NXXqWVZsOmh? MorExsBqdmirYnn0d{BieG:ydH;zbZMh[W6mIH\hZ4ltcXSjdHXzJIF2fG:yaHHnfUBqdiCGRV7WNk1qdm[nY4Tl[EBGSS6qeUmyOi=> NV3ZOWdPOjVzM{i3NFM>
Ebs M2PFfWFxd3C2b4Ppd{BCe3OjeR?= NWPicmlsOTBvMUCw{txO MlfsNlRp M4DD[eKhVU2WUzDn[Y5memG2aX;uJJJifGViZHXjdoVie2WmIHHzJJRp\SClb37j[Y51emG2aX;uJI9nKHpvVlHEMoZucyCrbnPy[YF{\WR? NHXWXFMzPTF|NEixOy=>
Jurkat Mn3NRZBweHSxc3nzJGF{e2G7 M4HENVIx|ryP MlHMNlRp NVLORVlYTE2VTx?= M1\MfZBienSrYXzsfUBqdmirYnn0JINmdGxiZHXheIghd2ZiSoXyb4F1KGOnbHzzJIlv\HWlZXSgZpkhOTByNUitSlQh[2:vYnnu[YQhf2m2aDDWVGHDqA>? NULveGdkOjVzMkC3NlM>
K562 NVTDUollSXCxcITvd4l{KEG|c3H5 M3nNc|AvOS1zzszN NWTWOXZIOWh? M3rnbIlvcGmkaYTzJINt\WG4YXflJI9nKEiVUEmwJIlvKGFiZH;z[U1l\XCnbnTlcpQhdWGwbnXy M37iOlI2OTF7MUi4
IMR-32 M1Pn[2Fxd3C2b4Ppd{BCe3OjeR?= MUK0NOKh|ryPwrC= MoHZNog> NGezfJJl\WO{ZXHz[UBqdiCjcH;weI91cWNiY3XscJMh[2:vcHHy[YQhfG9iVD2yJJRwgGmw M1T2fFI2ODh2N{W1
RPMI 8226 MlzDRZBweHSxc3nzJGF{e2G7 NIX3XGgyODEQvF2= M{e5NFFp MX;hcI1we3RiY3;tdIxmfGWueTDicI9kc3NiY3XscEBl\WG2aDDjZZV{\WRiYomgcoVkem:|dHH0bY4uOQ>? MkfvNlUxOzd6NUG=
U266  NWq0U2N{SXCxcITvd4l{KEG|c3H5 M1nUelExOM7:TR?= MkjkNYg> MUHwZZJ1cWGubImgZoxw[2u|IHPlcIwh\GWjdHigZ4F2e2WmIHL5JI5m[3Kxc4TheIlvNTF? M1q2bVI2ODN5OEWx
H929  MkTVRZBweHSxc3nzJGF{e2G7 NYnKZYpCOTByzszN NGrxdpgycA>? NH3TPXpx[XK2aXHscJkh[myxY3vzJINmdGxiZHXheIgh[2G3c3XkJIJ6KG6nY4Lvd5RifGmwLUG= NGm5c3UzPTB|N{i1NS=>
MM.1S  MUfBdI9xfG:|aYOgRZN{[Xl? NUDDPGk2OTByzszN NH;SUm8ycA>? Mn3n[YZncWOrZX70cJkheHKndnXueJMhe2:{YX\lcoljNWmwZIXj[YQh[2WubDDk[YF1cCClb33ibY5mKHerdHigcoVkem:|dHH0bY4uOQ>? NF7yeXgzPTB|N{i1NS=>
C6 NVzCPZZqSXCxcITvd4l{KEG|c3H5 NXq5Rms6PTEQvF2= M4XBZlQ5cA>? NXjTWpNWeHKndnXueJMhfGinIHzvd5Mhd2ZiY3XscEB3cWGkaXzpeJkh[2G3c3XkJIJ6KHC{ZXfu[Y5wdG:wZR?= NY\rU4JOOjVyMUO0O|k>
AGS M{fIOmFxd3C2b4Ppd{BCe3OjeR?= NWHGclJlPTEQvF2= M{XpN|I1cA>? NVX6SW93[WKxbHnzbJMh|rJvbHHwZYNpd26nLXnu[JVk\WRiY3XscEBl\WG2aDDhcoQhcW6qaXLpeIVlKGe{b4f0bC=> NU\aWZo5OjVyMEm2PVg>
HeLa  NWmxNINzSXCxcITvd4l{KEG|c3H5 NHGyXWY1OM7:TR?= MoDMNlRp NEC0bHVqdmirYnn0d{B1cGViaX7jdoVie2WmIHHwc5B1d3OrczDpcoR2[2WmIHL5JJNqWk6IMUKx NH\jdpIzPDl{OE[4OS=>
THP-1  MYHBdI9xfG:|aYOgRZN{[Xl? NX:5VodNOTEQvF2= NGfYb|QycA>? MX;y[YR2[2W|IHHwc5B1d3OrczDpcoR2[2WmIHL5JGFNSS2VRGVCpC=> MmHKNlQ6OjN4NUO=
P815  NF\tZoxCeG:ydH;zbZMhSXO|YYm= MUmxNFAhyrWP NIX5[pMyOmh? MkXoSG1UVw>? NFfSUoVqdmirYnn0d{B3cXK3cz3pcoR2[2WmIHHwc5B1d3Orcx?= MWKyOFkzOzJ5Mx?=
HCT116 MVHBdI9xfG:|aYOgRZN{[Xl? MoTZNlDPxE1? MWiyOIg> M{TSUYFjem:pYYTld{Bw\iCWUT3pcoR2[2WmIHHwc5B1d3Or NWXJOVN6OjR6OUC0OFk>
SW1116  MUnBdI9xfG:|aYOgRZN{[Xl? Ml\ZNVAhyrWP MV6xbC=> NV2xRYx7TE2VTx?= M{fINZJme3S{YXnud{Bk\WyuIHHwc5B1d3OrczDpcoR2[2WmIHL5JIdm\mm2aX7pZkBxdHW|IHTlZ4l1[WKrbnW= M{S4O|I1QDd2Mki2
LOVO MkTpRZBweHSxc3nzJGF{e2G7 MkLMNVAhyrWP NFTp[lcycA>? M1fsb2ROW09? MmjTdoV{fHKjaX7zJINmdGxiYYDvdJRwe2m|IHnu[JVk\WRiYomg[4VncXSrbnniJJBtfXNiZHXjbZRi[mmwZR?= MWmyOFg4PDJ6Nh?=
SNU449  M{DmWGFxd3C2b4Ppd{BCe3OjeR?= M4XBNFIx|ryP MXe0PIg> MVvEUXNQ M1Sy[IRm[3KnYYPld{BucVJvNEWxMYlv\HWlZXSgZZBweHSxdHnj M{DrclI1QDRzNkO4
Caco-2 MYHBdI9xfG:|aYOgRZN{[Xl? M{nFNVQx6oDLzszN M{GxbVRp NXTkWWtPeHKndnXueJMhW1RvNz3pcoR2[2WmIGrPMVEh[2ijbnfld{BidmRiVFXSJIRzd3B? MUGyOFgzOjF6Mx?=
macrophage MV\D[YxtKF[rYXLpcIl1gSCDc4PhfS=> M162OVAuOjByzszN MkHPNlRp NVfzS3J6cW6mdXPld{BVVkZvIHHu[EBTcXB|LXTldIVv\GWwdDDu[YNzd3C2b4Ppd{BqdiCvYXPyc5Bp[Wen NGTINJQzPDd7OUW2OS=>
AGS  MkC4RZBweHSxc3nzJGF{e2G7 NVu0U2RzOjEQvF2= MkHaNVJp M3vZNmROW09? NVvSO|BnemWmdXPld{B1cGViaX7keYN1cW:wIH;mJIFxd3C2b4Ppd{BqdiC{ZYPwc45{\SC2bzD0bIUhTXSRQXOg[pJi[3Srb36gbY4h[SCmb4PlMYRmeGWwZHXueEBu[W6wZYK= NXnUUJhDOjR5OEm3NFM>
LCC9  NYC1T4ZHS2WubDDWbYFjcWyrdImgRZN{[Xl? NGnlV3YyODEQvF2= MlO4OYQ> MVvicI9kc3NiY3XscEBl\WG2aDDpcoR2[2WmIHL5JINwdWKrbnH0bY9vKExzNzDhcoQh[2iub4LvdZVqdmV? MUWyOFc5PTJ3Nh?=
U937  Mn[2coVkem:ydH;zbZMhSXO|YYm= MnLzNVDDqM7:TR?= M3TTTlMxyqCvaX6= MXLpcoR2[2W|IH7lZ5JweHSxc3nzJINwdWKrbnWge4l1cCCWTl[= MmDYNlQ4PzN5NU[=
T cell M2fLUWNmdGxicILvcIln\XKjdHnvckBie3OjeR?= NYj6[nl3OC1zMEFOwG0> MoTzO|Jp NVLSe4xmUUN3ME23NEDPxE1uIHnubIljcXS|IHHueIkuS0R|LXnu[JVk\WRiVDDj[YxtKHC{b3zp[oVz[XSrb36gbY4hWEKPQ4O= NHzYeZMzPDd4OEewOy=>
HeLa  MXzBdI9xfG:|aYOgRZN{[Xl? NWD3emFmPTEQvF2= NW\zSItRPzKq M2PCPWROW09? NE\5PItxemW4ZX70d{BieG:ydH;zbZMhcW6mdXPl[EBjgSClb33wc5Vv\HQEoEJihLM2 MoKyNlQ4PTR5OE[=
HeLa  M2nWfGFxd3C2b4Ppd{BCe3OjeR?= MV6xNFDPxE1? MkmwNlRp MlHXd5VxeHKnc4Pld{Bz[XSnIH;mJINmdGxiZHXheIghcW6mdXPl[EBjgSCxdnXy[ZhxemW|c3nvckBw\iCJNUnTJI9zKEd5MWKgdFE2OGeudXXkxsA> NVexflViOjR5MkK0Olg>
IEC-6  M1zEWWFxd3C2b4Ppd{BCe3OjeR?= NHu0RnAyOM7:TR?= MlnaNlRp Mn7rdJJmfmWwdIOgWINlSS2rbnT1Z4VlKGOjc4Dhd4UuOyClbHXheoFo\SCjbnSg{tIu[2G2ZX7pckBl\We{YXTheIlwdg>? NEHvS|AzPDdzMUW3NS=>
HCT116 NIX3[4xCeG:ydH;zbZMhSXO|YYm= MX:yNO69VQ>? MU[yOIg> MoPobY5pcWKrdIOgeIhmKGOnbHygZZBweHSxdHnjJIlv\HWlZXSgZpkhYUyWMkC1 NYr2ZnQzOjR5MUO4NVI>
L02 NE\rboVCeG:ydH;zbZMhSXO|YYm= NHL2N48zOM7:TR?= Mn3NNYg> MYXwdoV3\W62czD0bIUh[2WubDDhdI9xfG:|aYOgbY5lfWOnZDDifUBOTUiS NU\ibWd2OjR5ME[0OlE>
A375 MXnBdI9xfG:|aYOgRZN{[Xl? M{\5flIx|ryP M37FVlI1cA>? M1POOJJmfmW{c3XzJIRq[2m2cnnuc45mKEJvaX7keYNm\CCjcH;weI9{cXN? NYrGZ49POjR4OUmxNVE>
HDPC MVnBdI9xfG:|aYOgRZN{[Xl? NIjLfHI2OML3TR?= MoP2NlRp MXPpcohq[mm2czDOU{1qdmS3Y3XkJIFxd3C2b4Ppdy=> MlLFNlQ3OzR3OUO=
A549 MWjBdI9xfG:|aYOgRZN{[Xl? NIDacIU2OML3TR?= MV6ybC=> MkjQSG1UVw>? M3H3XZBz\X[nboTzJJRp\SCqeYDv[IlxdG:rZDDEUmEh[2:wdHXueEBxcGG|ZTDpcoR2[2WmIHL5JINmeGijbH;jbJJwdWmw MnzHNlQ2QDhzM{W=
 BV-2 NUfpO5NbSXCxcITvd4l{KEG|c3H5 NYDZN49ZOjEQvF2= NHnYXGQzcA>? M2LTSZN2eHC{ZYPz[ZMhXVZvaX7keYNm\CClaILvcYF1cW5iZYj0dpV{cW:wIHHu[EBlcWyjdHnvckBw\iC2aHWgcpVkdGWjcjDlcpZmdG:yZR?= MnnwNlQ2PThzMUi=
HT-29  MUXBdI9xfG:|aYOgRZN{[Xl? NIqybZY2OM7:TR?= NGHtOVU1QGh? MmP0Zoxw[2u|IITo[UBieG:ydH;zbZMhcW6mdXPl[EBjgSCtYXXtdIZmem:u MYOyOFU1QTF5NR?=
A549 NV3CSFY4SXCxcITvd4l{KEG|c3H5 MYq1{txO M4Tt[lI1cA>? NYjSWlI6e3WycILld5NmeyB4ZdMgLGJMOTByNECpMYlv\HWlZXSgZZBweHSxc3nzxsA> M1zUe|I1PTJ7OEex
MIA-PaCa-2 M2fadGFxd3C2b4Ppd{BCe3OjeR?= MljDNlRp NWKyPXJX[myxY3vzJINt\WG4YXflJI9nKGOjc4Dhd4UuOyCrbnT1Z4VlKGK7IHLveIghSS12NEO2OVQh[W6mIIDhZ4xqfGG6ZXy= NUPNZ4NlOjR3MUC5PVI>
Caki-1 MVXBdI9xfG:|aYOgRZN{[Xl? MXeyNO69VQ>? NX:yOpF4OWh? MVPpcohq[mm2czDTR3AucW6mdXPl[EBieG:ydH;zbZM> Mm\DNlQ2ODR4OEG=
CLL NEfFRZZCeG:ydH;zbZMhSXO|YYm= NGTwOHIzPc7:TR?= MWexbC=> NGnCfo1x[XK2aXHscJkh[myxY3vzJG1NVjJ{M{itbY5lfWOnZDDj[YxtKGGyb4D0c5Nqew>? MV:yOFQ3PzZ|NB?=
SGC-7901 NHnBV4lCeG:ydH;zbZMhSXO|YYm= NFjGUnkyOM7:TR?= NFrxWYQzPGh? M4rmdJBzd22xdHXzJJRp\SCFR1nJMYlvcGmkaYTl[EBk\WyuIHfyc5d1cCCrbjDTS2MuPzlyMTDj[Yxtew>? M1fnW|I1PDV2NEi4
k1735 M2Tk[GFxd3C2b4Ppd{BCe3OjeR?= Mly2NlDjiIoQvH2= MWe0bC=> NYLONGpkcW6qaXLpeJPDqFOjbH3vcoVtdGFvaX7keYNm\CCjcH;weI9{cXN? MlvTNlQ1PTFzMU[=
HaCaT  NWPDXHJ2SXCxcITvd4l{KEG|c3H5 MX2xNFDPxE1? MoPkNYg> MmOwZox2dnS|IGXWRk1qdmS3Y3XkJIFxd3C2b4Ppd{BqdiCKYVPhWEBk\Wyucx?= NF3TVGIzPDN3Nkm5Oy=>
podocytes NXjW[m9MSXCxcITvd4l{KEG|c3H5 MV6yNFDPxE1? M12weFZp M3LPSolvcGmkaYTzJIFxd3C2b4Ppd{BqdmS3Y3XkJIJ6KDNuND3ES2U> NGrLV4szPDN|N{e3Oy=>
 KB NUL0WXV1SXCxcITvd4l{KEG|c3H5 M2jSNVUx|ryP NYDHeGdCOjSq M1XPSolvcGmkaYTzJGxq[29vQT3pcoR2[2WmIHPhd5Bie2VvMzDhcoQhWEGUUDDhZ5RqfmG2aX;u NUK0PGltOjR|M{e0PVI>
 HepG2  M4LxRWFxd3C2b4Ppd{BCe3OjeR?= MXexNO69VQ>? NXz1cJN{OjSq MYHy[YR2[2W|II\pcYVvfGmwIHPs[YF3[WenIHPheZNm\CCkeTDMVHM> MUSyOFMzPThzNh?=
fetal rat lung fibroblasts  NGTG[oJMcW6jc3WgRZN{[Xl? NV:wWXl7QDEQvF5CpC=> MnW4NYg> NVq3N2FVcW6qaXLpeJMhS2G|cHHz[U0{KGGldHn2bZR6yqB? MnjJNlQ{OTRzM{W=
PDL fibroblasts NULFOYRWU2mwYYPlJGF{e2G7 M1rGT|gx|ryPwrC= NVOzeVZyOWh? M4TteIlvcGmkaYTzJGNie3Cjc3WtN{Bi[3Srdnn0feKh MlrlNlQ{OTRzM{W=
MB49 NWTsZlQ4SXCxcITvd4l{KEG|c3H5 MorvNlDPxE1? M2q4WVFp MX7y[ZZmenOnczDDUU1qdmS3Y3XkJINmdGxiZHXheIg> MXmyOFI5OjR|Mx?=
5637 NXywcWUzSXCxcITvd4l{KEG|c3H5 NIL1dmUzOM7:TR?= NG\PS40ycA>? MV\y[ZZmenOnczDDUU1qdmS3Y3XkJINmdGxiZHXheIg> Mly3NlQzQDJ2M{O=
A549  NVWze21jSXCxcITvd4l{KEG|c3H5 NEjkO3UyODEQvF2= NUfmZW9NPDiq NWi0XHRwe3WycILld5NmeyC2aHWgZZBweHSxc3nzJINifXOnZDDifUBxcXCncnnu[eKh NFnEN2ozPDJ5MkKwNS=>
MCC-2 MVfBdI9xfG:|aYOgRZN{[Xl? NUDFV5B2OjBizszN NVLxdGNNPmh? NXTDNHM2TE2VTx?= NVrHfWhq[myxY3vzJIlv\HWlZXSgZpkhe3SjdYLvd5BwemmwZTDhdI9xfG:|aYOgZ4VtdCCmZXH0bC=> MojlNlQzPjJ4NUi=
ADF M2TBO2Fxd3C2b4Ppd{BCe3OjeR?= MYq0NO69VQ>? NEK5W5A3cA>? MUjpcohq[mm2czDhdI9xfG:|aYOgbY5lfWOnZDDifUBkcGWvb4To[ZJieHlicHz1d{BbdkOuMh?= M3;tW|I1OjJ6MkOy
 U373  MnryRZBweHSxc3nzJGF{e2G7 NXPoVXY1PDEQvF2= MlzxOog> NXjabY9KcW6qaXLpeJMh[XCxcITvd4l{KGmwZIXj[YQh[nliY3jlcY91cGW{YYD5JJBtfXNiWn7DcFI> NEnVWIEzPDJ{OEKzNi=>
RKO-HIPK2i NF3ST4xCeG:ydH;zbZMhSXO|YYm= NGjoWIk1OM7:TR?= M3vMfFZp NUf1SW9ncW6qaXLpeJMh[XCxcITvd4l{KGmwZIXj[YQh[nliY3jlcY91cGW{YYD5JJBtfXNiWn7DcFI> MnHrNlQzOjh{M{K=
HEC-1B M1PUcGFxd3C2b4Ppd{BCe3OjeR?= NFPlbmEzOM7:TR?= M3jBWFFp MnH4doVlfWOnczDUVE1qdmS3Y3XkJIFxd3C2b4Ppd:Kh[2G|cHHz[U0{KGGwZDDjZZNx[XOnLUm= NYW5SIdUOjR{MUOzOVg>
4T1 MoP2R4VtdCCYaXHibYxqfHliQYPzZZk> NXPjNXJ1Oi53LUGw{txO NUn1eY1[PGh? MofISG1UVw>? M13HU5Jme2O3ZYOgeIhmKGO7dH;0c5hq[2m2eTDv[kA1XDFiY3XscJMhcW6mdXPl[EBjgSCVUFTUJIlvKGFiY3;uZ4VvfHKjdHnvckBl\XCnbnTlcpQhdWGwbnXy NXLDephKOjR{ME[xOlE>
OS  NYPwXnVWSXCxcITvd4l{KEG|c3H5 NW\BOYpmOjEQvF2= MYW0bC=> NXX4[5RWcW6qaXLpeJMhfGinIHPlcIwh\GWjdHigZ4F2e2WmIHL5JHBFXA>? M1i0TFI1OjB2OUO3
RPE NIHwWXBCeG:ydH;zbZMhSXO|YYm= NEnmdoUyODEQvF2= MXS0PIg> NYTySYtLeGG{dHnhcIx6KGmwaHnibZR{KHSqZTDjZYxx[WmwLUGgZY5lKC1{IHHjeIl3[XSrb36gZZMhf2WubDDhd{B1cGViY3HzdIF{\SCjY4TpeoF1cW:w NX;0PVRmOjR{MEKwOVI>
UD29a MnTSRZBweHSxc3nzJGF{e2G7 NWD3cIhvPTEQvF2= NXfUUmRlOjSq NFz6[21qdmirYnn0d{B1cGViY3XscEBl\WG2aDDjZZV{\WRiYomgUnVVOw>? MXiyOFE6ODV5NB?=
SH-SY5Y  MV\BdI9xfG:|aYOgRZN{[Xl? MVOxNO69VQ>? MknkNlRp M{GwToF1fGWwdXH0[ZMh[2G|cHHz[UBi[3SrdnH0bY9vKGGwZDDj[YxtKGSnYYToJIlv\HWlZXSgZpkhUE6HLULESy=> NF7rVIkzPDF2NUS2Ny=>
HeLa  NID0VI5CeG:ydH;zbZMhSXO|YYm= NH72WXQyOC9{MN88US=> MVKyOIg> MX3pcohq[mm2czD0bIUh[WO2aY\peJkhd2ZidHjlJI1icm:{aYT5JI9nKHSqZTDt[Y1j\XK|IH;mJJRp\SClYYPwZZNmNW[jbXnsfS=> M{\qfVI1OTN5Mk[2
SCCVII  MnnZRZBweHSxc3nzJGF{e2G7 NVL6doFkOjYQvF2= NHP1RpUycA>? MYXpcohq[mm2czD0bIUh[2WubDDrbYxtcW6pIHHmeIVzKGSjc3H0bY5q[g>? MXmyOFEzPjR4NB?=
RAW 264.7 NWDiSW9ISXCxcITvd4l{KEG|c3H5 M1\rOFIx|ryP Mof1NVhp MYXpcoNz\WG|ZYOgUGM{NUmLL98yMYFkfGmwIILheIlwKGOxbYDhdoVlKHSxIFXDWHYuVU:VIITy[YF1dWWwdDDvcox6 M13CeVI1OTF4N{C3
A549  NV75[W9NSXCxcITvd4l{KEG|c3H5 MU[yMlXPxE1? NVTlWIFTOjSq NELTVFll\WO{ZXHz[ZMhd3KrZH;ubY4ucW6mdXPl[EBifXSxcHjh[5kh[XNid3XscEBidmRiTH;zd{Bw\iEQlN-IcUBidHOxIH;jZ5VzemWmIHT1dolv\yCjdYTvdIhi\2mlIIDyc4Nme3N? MXSyOFExOjV{Mh?=
UM-SCC-10A  NFzYW5lCeG:ydH;zbZMhSXO|YYm= MWe1NOK2VQ>? MV2ybC=> MY\y[YR2[2W|IHHwc5B1d3OrczDpcoR2[2WmIHL5JIhq\2hvZH;z[UBqe2:jbHHueI9t[WO2b37l MVOyOFA6QDd3Mx?=
BGC-823 MkizRZBweHSxc3nzJGF{e2G7 NFLiTIsyOCEQvF2= MoH0NlRp NHvPNIZz\WS3Y3XzJJRmfHKjbnTybY5mNWmwZIXj[YQh[XCxcITvd4l{yqB? NG[4NVMzPDB7OEWxNS=>
Nalm-6  MY\BdI9xfG:|aYOgRZN{[Xl? NWi3e20xOjEQvF2= M1:zTVRp MVTpcohq[mm2czDjZZNx[XOnLUigZY5lKGOjc4Dhd4UuOyCjY4TpeoF1cW:wIHHu[EBRSVKSLUGgZ4xm[X[jZ3W= NHTCOHgzPDB|OUm2Oy=>
KHOS  NUXjbVRnSXCxcITvd4l{KEG|c3H5 Mk[2OFDPxE1? NHjl[20zPGh? MUjicI9kc3NidHjlJIlv[3KnYYPl[EBkdGWjdnHn[UBw\iClYYPwZZNmNTNiYX7kJHBCWlBiaX7keYNm\CCkeTDCRm1FO8Li Mk\tNlQxOjV|NkG=
G292 MlP2RZBweHSxc3nzJGF{e2G7 MWC0NO69VQ>? NFvwOpozPGh? M4jLU4Jtd2OtczD0bIUhcW6lcnXhd4VlKGOuZXH2ZYdmKG:oIHPhd5Bie2VvMzDhcoQhWEGUUDDpcoR2[2WmIHL5JGJDVUR|wrC= M{nVO|I1ODJ3M{[x
MG-63 NV;yfllMSXCxcITvd4l{KEG|c3H5 NXf5V5RMPDEQvF2= NVvWfZplOjSq Mlz2Zoxw[2u|IITo[UBqdmO{ZXHz[YQh[2ynYY\h[4Uhd2ZiY3HzdIF{\S1|IHHu[EBRSVKSIHnu[JVk\WRiYomgRmJOTDQEoB?= M33sNlI1ODJ3M{[x
EBV-transformed B cells NWfvbG5oSXCxcITvd4l{KEG|c3H5 NILj[nIzOM7:TR?= Mn\6Nog> M{\TSGROW09? NUfEbmxu[myxY3vzJIFvfGlvQ1S4NEBidmRiYX70bU1ETDh4IHHueIljd2S7LXnu[JVk\WRiYYDvdJRwe2m| NEXZN44zPDByOE[yPC=>
IM-9 B M2mxeWFxd3C2b4Ppd{BCe3OjeR?= NFPRToczOM7:TR?= NYfkbY9xOmh? MlLTSG1UVw>? M2KweoJtd2OtczDhcpRqNUOGOECgZY5lKGGwdHmtR2Q5PiCjboTpZo9lgS2rbnT1Z4VlKGGyb4D0c5Nqew>? NWHJfm1IOjRyMEi2Nlg>
CNE1 MnnpRZBweHSxc3nzJGF{e2G7 Mn3vNlDPxE1? MoTTOFhp MofrZoxw[2u|IFzLMWEucW6mdXPl[EBieG:ydH;zbZM> NVL1U2t4OjN7OEWwNlk>
CNE2 M1jnXWFxd3C2b4Ppd{BCe3OjeR?= MVqyNO69VQ>? NVfLeYN{PDiq NVXEV5I4[myxY3vzJGxMNUFvaX7keYNm\CCjcH;weI9{cXN? MXSyN|k5PTB{OR?=
HL-60 MV3BdI9xfG:|aYOgRZN{[Xl? NGm4XJk2OML3TR?= M2jkWlFp MWfEUXNQ M{jP[YlvcGmkaYTzJIFxd3C2b4Ppd{BqdmS3Y3XkJIJ6KEKDMUS1 M3TTclI{QTR6N{Wx
L929 NH2xVHdCeG:ydH;zbZMhSXO|YYm= NWT3O5o1OS5{NfMAl|XDqM7:TdMg MnnPNlRp MnLtZZVodWWwdIOgWG5H|rFvaX7keYNm\CCwZXPyc5B1d3OrczDhcoQh[XW2b4DoZYd6 MmDkNlM6PDF5Nkm=
Jurkat MX7D[YxtKF[rYXLpcIl1gSCDc4PhfS=> NHf1PXYz|ryP NYPZeYZuPGh? NYX1cI9yemW4ZYLz[ZMh\3Kxd4ToJIlvcGmkaYTpc44h[W6mIN8yMYNifGWwaX6g[IVkemWjc3WgZpkhUFNvQWPB MljKNlM5QTZyNkG=
RAW264.7  NUjqc5ZySXCxcITvd4l{KEG|c3H5 M3XRRlExKM7:TR?= NVfZNJVmOjSq M1XmVoRm[3KnYYPld{B1cGViYYDvdJRwe2m|IHnu[JVk\WRiYomgS2E> MUGyN|gzODJyMx?=
A431  MYjLbY5ie2ViQYPzZZk> M1f5UFQx|ryP MViybC=> MXTicI9kc3NiZnnz[ZRqdi2rbnT1Z4VlKGOuZXH2ZYdmKG:oIHPhd5Bie2W|IHHu[EBRSVKS NXPHO|NVOjN6MECwOVg>
Jurkat MV3D[YxtKF[rYXLpcIl1gSCDc4PhfS=> Mn\jNlUuOTByzszN NV75SWNpPmh? MYLpcohq[mm2czD6MWZCNUOPSz3pcoR2[2WmIHPlcIwh\GWjdHi= NGKyNYszOzl|M{WzNi=>
COS-7  NYLNfWlbTnWwY4Tpc44hSXO|YYm= NI\ic2s2OML3TR?= NET2eWEzPGh? MmntZYZn\WO2czD0bIUheHKxY3Xzd4lv\yCxZjDBWG4yeyC5aYToJJBwdHmTIITyZYN1ew>? MkPPNlM6OzN{MEi=
CAL27 MVPBdI9xfG:|aYOgRZN{[Xl? MU[xNEDPxE1? M32xZlJp NH\jS2l{fXCycnXzd4V{KEO3cj3OVJMuemWmdXPl[EB3cWGkaXzpeJkh[nlidYCgeI8hQTBn NV3sPXI3OjN7MUezPVY>
THP-1  MUnBdI9xfG:|aYOgRZN{[Xl? NYrzc2ZYOTBvNUFOwG0> M120NlJp MmD4bY5pcWKrdIOgZZBweHSxc3nzJIlv\HWlZXSgZpkhfHKrcITvcIll\Q>? M{nhcVI{QTByMkm5
K562 Ml\NRZBweHSxc3nzJGF{e2G7 M17NXlIx|ryP MnTWOFhp MnywbY5pcWKrdIOgZZBweHSxc3nzJIlv\HWlZXSgZpkhPC2PVR?= MVSyN|g4Pjh{Nh?=
HL-60 NH;ZT4NCeG:ydH;zbZMhSXO|YYm= M{TtNVExOM7:TR?= MnXuNlRp NGLndoFqdmirYnn0d{BieG:ydH;zbZMhcW6mdXPl[EBjgSCjYnnleIFv\SCmaYTldpBmdmW|wrC= NXrkO3RzOjN6NkW3O|g>
HeLa  MUXBdI9xfG:|aYOgRZN{[Xl? MUCyNO69VQ>? NIHDUnkzcA>? M{fYTYlvcGmkaYTzJGROVVBiaX7keYNm\CCjcH;weI9{cXN? NFzZfZQzOzh4M{m2Oi=>
U251 MWjBdI9xfG:|aYOgRZN{[Xl? MVqyNO69VQ>? NFfrfm4zPGh? M36wXIlvcGmkaYTzJINie3SrY3nuJIlv\HWlZXSgS|IwVSCyaHHz[UBienKnc4SgZY5lKGGyb4D0c5Nqew>? Mn7CNlM5OTZ6MU[=
HL-60 M4DoZWFxd3C2b4Ppd{BCe3OjeR?= MnTnOVDDvU1? M3vvR|Rp NUj4Xohk[myxY3vzJJRp\SClbHXheoFo\SCxZjDjZZNx[XOnLUOsJE06NCCjbnSgVGFTWCCrbnT1Z4VlKGK7IE\z M4XEdVI{QDB2N{C2
Ec-109 MlLTRZBweHSxc3nzJGF{e2G7 NVrZ[XNZOTBizszN NH64[2I1QGh? MULy[ZBz\XO|ZYOgVGUudWWmaXH0[YQhTWNvMUC5JINmdGxiYYDvdJRwe2m| NV36cId{OjN5OEK2OFE>
RKO NYHt[5R3S2WubDDWbYFjcWyrdImgRZN{[Xl? MYmxNEDPxE1? NX\ISoJlOjSq NEW5dYtqdmirYnn0d{B1cGViZHXjdoVie2Vib3[gZ4VtdCC4aXHibYxqfHliY3H1d4VlKGK7IFTBRi=> MYmyN|c2QDB4NB?=
T98G M1HGVWNmdGxiVnnhZoltcXS7IFHzd4F6 NILIVVQyNTFyMN88US=> M37BfFI1cA>? MojObY1xem:4ZYOgZ4VtdCC4aXHibYxqfHliY3;0doVifG2nboSge4l1cCCWUx?= M{HJO|I{PzZ7Mke1
Jurkat M334fmNmdGxiVnnhZoltcXS7IFHzd4F6 NHPUNpUyODBvMkCw{txO M4jjTVI1cA>? MoP4bY5pcWKrdIOgTIFCPCCrbnT1Z4V{KGGyb4D0c5NqeyCmZYDlcoRmdnRib3[gZ49v[2WwdILheIlwdsLi M163TFI{PzN{NEix
Molt-3  M2HXc2Fxd3C2b4Ppd{BCe3OjeR?= NWPlXWdZPTEQvF2= NIXIeZQzcA>? MX;y[YR2[2W|IH3lcIF1d26rbj3pcoR2[2WmIHHwc5B1d3Orcx?= MYKyN|czPTBzMx?=
hMSC12 NUXVXY1jSXCxcITvd4l{KEG|c3H5 NUTaSmtnOTByzszN Mn[4OIQ> MVXpcohq[mm2czDvd5Rmd2enbnnjJIN2dHS3cnWtbY5lfWOnZDDj[YxtKGSnYYToJIFv\CClYXzjbYZq[2G2aX;u NIrSeXAzOzZ3N{iyNi=>
HM7  MV3BdI9xfG:|aYOgRZN{[Xl? MnKwNlDPxE4EoB?= NFj2NHQycA>? MW\icI9kc3NiYYDpZ5Vt[XKnbjDBJIFk\XSjdHWtbY5lfWOnZDDjZZNx[XOnLUOgZYN1cX[jdHnvckBidmRiUFHSVEBkdGWjdnHn[S=> MXSyN|U5OzRzMh?=
Hep-2  MWPBdI9xfG:|aYOgRZN{[Xl? MWCyNO69VcLi MkXENlRp M{\aOmROW09? MWfhcIxmfmmjdHXzJJRp\SCmZXPy[YF{\SCxZjDj[YxtKH[rYXLpcIl1gSCrbnT1Z4VlKGK7IIPpcIljcW6rbh?= M17EVFI{PThyMEOy
HSCs M4LNU2Fxd3C2b4Ppd{BCe3OjeR?= NIDHbW82OM7:TR?= NHrucFEzPGh? NUPVZ2dtTE2VTx?= M13FcYlvcGmkaYTzJI5qdG:2aX7pZk1qdmS3Y3XkJGRPSSCmYX3h[4UhcW6maXPheIVlKGK7IGDBVnAh[2ynYY\h[4U> M{fkfFI{PDl7OEe0
HL-60  Mn7tR5l1d3SxeHnjbZR6KEG|c3H5 M1PDc|Ix|ryPwrC= NIDUNmczPGh? MnzHdoVlfWOnczD0bIUh[3m2b4TvfIlkKGWoZnXjeEBw\iCHcom1 NF\BS2szOzR7NES4NC=>
HA M4GzN2Fxd3C2b4Ppd{BCe3OjeR?= M3vwd|Ux|ryP MUCyOIg> NXLlZpZpe3WycILld5NmeyC2aHWgZ4xm[X[jZ3Wgc4YhWEGUUDDhcoQh[2G|cHHz[U0{NCBvNzygZY5lKC17IHnu[JVk\WRiYomgZo9zfGW8b33pZk9USUiD Mnq1NlM1PzV7NU[=
C666-1 M3rFemFxd3C2b4Ppd{BCe3OjeR?= NHXhNZQ2OM7:TR?= M2jMNFI1cA>? NWL5SY5We3WycILld5NmeyC2aHWgZ4xm[X[jZ3Wgc4YhWEGUUDDhcoQh[2G|cHHz[U0{NCBvNzygZY5lKC17IHnu[JVk\WRiYomgZo9zfGW8b33pZk9USUiD MWGyN|Q4PTl3Nh?=
Hepa1-6 NIHPRoZCeG:ydH;zbZMhSXO|YYm= MX:1NO69VQ>? M2LDWFJp MVnpcohq[mm2czDjeZJkfW2rbjDhcoQhemW|dnXyZZRzd2xvaX7keYNm\CCjcH;weI9{cXN? MVyyN|Q1Pjd3Mx?=
PLC/PRF/5c M4mweGFxd3C2b4Ppd{BCe3OjeR?= NX7FXpZCPTEQvF2= Mkf2NYg> NHj6SpBxemW4ZX70d{BieG:ydH;zbZMhfHKrZ3fldoVlKGK7IFPJUi=> MnLwNlM1Ozh6MkS=
HCT116 Moq1RZBweHSxc3nzJGF{e2G7 MUOxNFDPxE1? NFLSXW8yNjWq M1rmeYlvcGmkaYTzJG9{NWmwZIXj[YQh[2WubDDk[YF1cA>? MWiyN|c1PDN3Mx?=
HCEC NHfiS2FHfW6ldHnvckBCe3OjeR?= MV[1NO69VQ>? MUO3Nog> NHnKSJJFVVOR M2TQ[ZJme3SxcnXzJI9nKHSqZTDuc5Ju[WxiSFPFR{BxcGWwb4T5dIU> MkLoNlM4PDJyMUG=
Primary rat cerebral cortical neurons NXTVbI54SXCxcITvd4l{KEG|c3H5 M1fLWVExOM7:TR?= M1;jdlFp M1;CWJBz\X[nboTzJGNlNWmwZIXj[YQh[XCxcITvd4l{KGGwZDDj[YxtKGSnYYTo M3XhTVI{PzRzM{G3
MDA-MB-231  NYH6RnFESXCxcITvd4l{KEG|c3H5 NFjCcHMzPc7:TR?= MmP3NlRp NXrqXGJV[WK{b3fheIV{KGO7dH;0c5hq[2m2eTDhcoQh[2ynYY\h[4Uhd2ZiY3HzdIF{\S1|IHHu[EBRSVKSIHnu[JVk\WRiYomgVoc{ NGnHOY0zPTN|N{W0OC=>
NLRP3-Tet-on-MC/9  NV2yb5JLSXCxcITvd4l{KEG|c3H5 NUL6WmJEOTBvNEFOwG0> M2HSU|EzcA>? MVnheJRmdnWjdHXzJJRp\SClZXzsJIRm[XSqIHPheZNm\CCkeTDDRXBUNWG|c3;jbYF1\WRiTlzSVFMhdXW2YX70d{BqdiC2aHWgWIV1NW:wIIP5d5RmdQ>? M37QT|I{PzB|M{i5
KNS42  MVPBdI9xfG:|aYOgRZN{[Xl? NHvQV3M2OM7:TR?= M1rSXVFp NX24W5M1emWmdXPld{Bk\WyuIHTlZZRpKGGwZDDjc41xdGW2ZXz5JIFjd2yrc3jl[EBk[XOyYYPlJFMwPyCjY4Tpeol1gSCrbjDy[ZNxd26|ZTD0c{BCSlRvMk[zM|JFTy:vZYTmc5JucW5iY3;tZolv[XSrb36= M1n1S|I{PjlzMUS1
MCF-7  NYDyXGt3SXCxcITvd4l{KEG|c3H5 NGPGdIwzOM7:TdMg NH62V5g4Omh? M3fYTolvcGmkaYTzJIVyfW:uLTDhcoQhPC2RSGStcYVlcWG2ZXSgZZBweHSxc3nz MkjiNlM3PzV4NEO=
hCMEC/D3  NF7mS4JCeG:ydH;zbZMhSXO|YYm= NE\KSmQzPc7:TR?= M1K2RlczcA>? MVzy[YR2[2W|IFz0fGEhcW6mdXPl[EBieG:ydH;zbZM> MXmyN|Y3PTF7OB?=
Jurkat M{XnZmFxd3C2b4Ppd{BCe3OjeR?= NUTobnNiOTJwNT21NO69VQ>? NFTh[IEycA>? NGOwboVld3OnIHTldIVv\GWwdHz5JJN2eHC{ZYPz[ZMhW1CKLXnu[JVk\WRiUHHyMVQh[2ynYY\h[4UtKFCDUmCgZ4xm[X[jZ3WsJGRPSSCocnHncYVvfGG2aX;uMEBidmRibH;zd{Bw\iC4aXHibYxqfHl? NEDiTWgzOzR2Mkm3Oi=>
CNE-1 NE\YN25CeG:ydH;zbZMhSXO|YYm= MUCyNO69VcLi MkW0NlRp M3[4TIlvcGmkaYTzJHJCTDByMT3pcoR2[2WmIHPlcIwh\GWjdHi= NVjGS4RVOjN2Mk[4OVA>
HONE-1 NFL3OHFCeG:ydH;zbZMhSXO|YYm= MluzNlDPxE4EoB?= NWXvVoJkOjSq MYjpcohq[mm2czDSRWQxODFvaX7keYNm\CClZXzsJIRm[XSq MmLDNlM1OjZ6NUC=
astrocytes cell MonKRZBweHSxc3nzJGF{e2G7 NUPxN|JGPDEQvF2= NXzKfHRNPmh? MoPHdoVlfWOnczDlZZJtgSCjcH;weI9{cXNiaX7keYNm\CCkeTDzeIF2em:|cH;ybY5m M1fwdFI{PDFzN{e4
U-937 NHHucpRCeG:ydH;zbZMhSXO|YYm= NYjDO4NTOTEQvF2= NHvER5o{OG2rbh?= NHL2OlRxemW4ZX70d{BVVkZvaX7keYNm\CCwZXPyc5B1d3Orcx?= NX3POlY4OjN2MUC3OFg>
MDA-MB-231 NX\B[IVZSXCxcITvd4l{KEG|c3H5 Mk\VNVAx|ryP MmW0NYg> Mn\RbY5pcWKrdIOgd4Vve2m2aYrheIlwdiC2bzDUVmFKVCC3cH;uJG1VTEhiZH;3ck1z\We3bHH0bY9v NFvPflIzOzRyOESyPS=>
HeLa  NF3Db5ZCeG:ydH;zbZMhSXO|YYm= M3XrbVExOM7:TR?= Ml;jNog> NVf1emFn[myxY3vzJGpTWy1zNTDJcoR2[2W|IFHwc5B1d3SrYzDD[YxtKESnYYTo MoS3NlM{PDRyNEW=
Ec109 MlfIRZBweHSxc3nzJGF{e2G7 M3PYR|Ex|ryP NFnYeGo3cA>? NHHQO4ljdG:la4OgZZBweHSxdHnjJINwdWKrbnH0bY9vKG:oIGTheE1UdWGlTkegZY5lKHKjZHnheIlwdg>? MVeyN|M{QDV4OB?=
H460  MmDMRZBweHSxc3nzJGF{e2G7 M4fTVVEx|ryP MY[2bC=> MkmxZoxw[2u|IHHwc5B1d3SrYzDjc41jcW6jdHnvckBw\iCWYYStV41i[055IHHu[EBz[WSrYYTpc44> NUjMdW43OjN|M{i1Olg>
HeLa  NFLMUGRCeG:ydH;zbZMhSXO|YYm= MXW1NO69VQ>? NGDsNJAyNjWq MV7hZpJw\2G2ZYRCpGNpdGGveXTpZU1qdmS3Y3XkJIFxd3C2b4Ppdy=> NVPrcXRCOjN|MEO4NFQ>
SK-HEP1 MUDBdI9xfG:|aYOgRZN{[Xl? NGTx[I8yODEQvF2= M2nYW|Fp NGXBcGFqdmirYnn0d{BEelRzIHHjeIl3[XSnZDDjZZNx[XOnLUOsJE04NCBvODygMVktKGGwZDDwc4x6MEGGUD3ybYJwe2VrIIDvcJlu\XKjc3W= M{Kw[FI{OzB{NkWw
QGY7701 NY\EdmxRSXCxcITvd4l{KEG|c3H5 M1TwWFI2|ryP NX64e|NyOS53aB?= MXvpcohq[mm2czDhZ4N2dXWuYYTpc44hd2Zic4XiMWcyKHCqYYPlJIlv\HWlZXSgZpkhTE:[IDugdZVmemOndHnu M3;6T|I{OjRyME[x
HepG2 M3XUNmFxd3C2b4Ppd{BCe3OjeR?= MVqyNO69VQ>? MlnFN|BucW5? M4fpcolvcGmkaYTzJJRp\SCnbnjhcoNm\CClZXzsJIRm[XSqIHL5JINwdWKrbnXkJJRz\WG2bXXueEBw\iCjcHnn[Y5qdiCjbnSgWHJCUUx? Mn3KNlMzOjR{M{m=
U87  NVrhTYltSXCxcITvd4l{KEG|c3H5 MV[yOe69VQ>? M3OwfFJp M{TYWoRm[3KnYYPld{Bqe2:uaYH1bZJqfGmpZX7pckApUVOOKT3pcoR2[2WmIHHwc5B1d3SrYzDj[YxtKGSnYYToMEBjfXRibn;0JI5m[3KxdHnjJINmdGxiZHXheIg> MX2yN|IzQTZ{Nh?=
HSC-2 MmLHRZBweHSxc3nzJGF{e2G7 Mm\JNlUwPTEQvF2= MnPBNYg> MVrpcohq[mm2czDTUk0{QC2rbnT1Z4VlKGO7dH;0c5hq[2m2eR?= MVuyN|E2PTJ2OB?=
HSC-4 MX;BdI9xfG:|aYOgRZN{[Xl? NF63bnAzPS93MN88US=> M{LjVVFp MUjpcohq[mm2czDTUk0{QC2rbnT1Z4VlKGO7dH;0c5hq[2m2eR?= NVf2OVFjOjNzNUWyOFg>
CL-1 NEfIO4lCeG:ydH;zbZMhSXO|YYm= M2DnNlIx|ryP MVOxbC=> Mnu0Zoxw[2u|IF;QOFQ6KGmwZIXj[YQh[2WubDDk[YF1cA>? MYqyN|E{OTd6Mh?=
MEL M2TZ[WFxd3C2b4Ppd{BCe3OjeR?= M1r1c|Ix|ryP M2LmcFI1cA>? MYLEUXNQ M3L6R4lueGGrcnXzJHAzYDdvaX7keYNm\CCPRVygZ4VtdCCjcH;weI9{cXN? MV2yN|AyPDh6Nx?=
Bel-7402  Mmf5R4F{eGG|ZTDBZ5RqfmG2aX;uJGF{e2G7 Mmm0OVDPxE1? MYCybC=> NVjQbJFWcW6qaXLpeJMhWEOHLXnu[JVk\WRiYX7vbYtqew>? MlTmNlMxODh5NEK=
Eca-109 Mn\aRZBweHSxc3nzJGF{e2G7 MlG5NlXPxE1? MmDoN|BucW5? NVvnS25YcW6qaXLpeJMhSkpvQkGxMYlv\HWlZXSgZ4VtdCCmZXH0bC=> NX\HXm83OjNyN{[5Olc>
MEL MVXBdI9xfG:|aYOgRZN{[Xl? NVPSPIJoOjEQvF2= NECySYgycA>? MnTKSG1UVw>? MlLkbY1x[Wm{ZYOgVFJZPy2rbnT1Z4VlKE2HTDDj[YxtKGGyb4D0c5Nqew>? MoHiNlMxOTR6OEe=
Bel-7402  MUHBdI9xfG:|aYOgRZN{[Xl? MoTmOVDPxE1? M{fyVFJp M4DQeolvcGmkaYTzJHBETS2rbnT1Z4VlKGGwb3nrbZM> M1TzXFI{ODB6N{Sy
L929 MojhSpVv[3Srb36gRZN{[Xl? MoDqNk42|ryP M2PVcVFp M{f4dIlv[3KnYYPld{BTUVBzIHX4dJJme3Orb36gZY5lKGW6YXPldoJifGWmIGTOSu6yNWmwZIXj[YQhdWm2b3Poc45lemmjbDDkfZNnfW6ldHnvckBidmRiUl;TJJBzd2S3Y4Tpc44> M4LsbVI{ODByNUG4
RCC  MkLlR4VtdCCYaXHibYxqfHliQYPzZZk> MX[xNFDPxE1? M163TFI1cA>? M4XxPJJm[2:4ZYLld{B1cGVidnnhZoltcXS7IH;mJINmdGy|IHX4dI9{\WRidH:gNVVlNVCJSkK= NWXpR5k5OjJ7OUG0PVQ>
NB2a/d1 NGPRTIVCeG:ydH;zbZMhSXO|YYm= NUnUNYprOTByzszN Ml60O|Jp MnXZZZR1\W63YYTld{B{fGG3cn;zdI9zcW6nLXnu[JVk\WRiY3HzdIF{\SCjY4Tpeol1gSxiUFHSVEwh[W6mIITheUBkdGWjdnHn[S=> Mny3NlI6QDh3NEG=
T cell MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV7q[lJXOjVvMUCw{txO NXPF[GtCOjSq MYrkc5NmNWSncHXu[IVvfGy7IHnubIljcXSnZDDUJINmdGxicILvcIln\XKjdHnvckBu\WSrYYTl[EB1cHKxdXfoJJRp\SClbz3zeIlufWyjdHnvckB4cXSqIHHueIkuS0R|IHHu[EBidnSrLVPENlg> MWiyNlk5OjV|OB?=
K562 NUK1OZN1SXCxcITvd4l{KEG|c3H5 MX[xNFDPxE1? NFraWXIycA>? NX;l[ZQ{[myxY3vzJGFjdm:kYY\pd4N2dcLiRj3pcoR2[2WmIHHwc5B1d3Orcx?= M2jud|IzQTd{M{ey
Jurkat  NGryWWpCeG:ydH;zbZMhSXO|YYm= NIe5PI81OM7:TR?= MnqxNYg> NITuNopi[m:uaYPo[ZMhTmG|TD3pcoR2[2WmIHPhd5Bie2ViYXP0bZZifGmxbjDhcoQh[2WubDDk[YF1cA>? Mmf6NlI6PDJ5M{i=
BGC-823 M3;RUGFxd3C2b4Ppd{BCe3OjeR?= Mm\4NVAx|ryP MXyxbC=> NHLPW4Jx[XK2aXHscJkhemW|Y4Xld{Bk\WyuczDh[4FqdnO2IHThcYFo\SCxZjDkZYllgmWrbh?= MkK2NlI6OjZ3NEW=
Hep3B NWX6T4JbSXCxcITvd4l{KEG|c3H5 NV31eIdOPTEQvF2= NHX1eI8ycA>? MnnlZoxw[2u|IHHwc5B1d3OrczDpcoR2[2WmIHL5JGhGT0O| M1PwflIzQTJ|MUW0
LLC-PK1 NVjUeJdoSXCxcITvd4l{KEG|c3H5 NX:3WWdjOjEQvF2= MljxNYg> MW\wdoV3\W62czDjbZNxdGG2aX6tbY5lfWOnZDDk[Ydz[WSjdHnvckBw\iCDdHe1MEBj\WOuaX6tNUwh[W6mIFH0[|EzKHC{b4TlbY5{ NHHXfpkzOjh7NkCzOy=>
A549 NFX2elNCeG:ydH;zbZMhSXO|YYm= M{S2dVUx|ryP NWL1OYhlOWh? MoDRZoxw[2u|IITo[UBDSUlvaX7keYNm\CCjcH;weI9{cXQEoB?= M3viNVIzQDh5MkG1
SGC-7901  NUXNZ4xSSXCxcITvd4l{KEG|c3H5 MWmxNO69VQ>? NV60NIcyOjSq NXzEdos6cW6qaXLpeJMh|rJuzsKt[Ilu\XSqeXzhZ5J6dHOqaXvvcolvNWmwZIXj[YQh[XCxcITvd4l{yqB? M4PBNVIzQDR6NUm3
DM6 NFj5bm1CeG:ydH;zbZMhSXO|YYm= MWCxNFDPxE1? MWW3Nog> M4HoNYJtd2OtczDic5RpKEV{Rj2xJIFv\CCHMl\0dk1u\WSrYYTl[EBkgXSxdH;4bYNqfHl? NXHH[ZpWOjJ6MkWzNlg>
MCF-7, MDA-MB-468, Caco-2 MkTGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NW\MWYVzPTEQvF2= MWW0PIg> NGqzcIhqdmirYnn0d{B1cGViY3XscEBoem:5dHigbY5pcWKrdHnvckBqdmS3Y3XkJIJ6KHOjcH;ubY4> MX[yNlgxODl4OB?=
A2750  MnPqRZBweHSxc3nzJGF{e2G7 Mn23NlDPxE1? MVuybC=> M4ficWROW09? NXi3UJQ{[myxY3vzJINie3Cjc3WgZ4xm[X[jZ3Wg[JVzcW6pIHjlcIVv[WyrbjD0doVifG2nboSgZY5lKHKnZIXj[ZMh[XW2b4DoZYdq[yClZXzsJIRm[XSq NV:zXGpGOjJ5OESzOlM>
U87  MUfBdI9xfG:|aYOgRZN{[Xl? NUjhToNUOjEQvF2= MmDxNlRp NEXncmNz\WS3Y3XzJJRp\SCjcH;weI9{cXNicnH0[UBqdmS3Y3XkJIJ6KFCOQVK= NFnmU24zOjd5OEe4NC=>
HT1080 NGfsSFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV:1NO69VQ>? MoXhO4Q> MYTpcohq[mm2czD0bIUh[2WubDDndo94fGhiaX7obYJqfGmxbjDjZZV{\WRiYomgZ49u[mmwZXSgeJJm[XSvZX70JI9nKESFQTDhcoQhV02S NEfBbJIzOjd2MEm4OC=>
A549  MYPBdI9xfG:|aYOgRZN{[Xl? NWfRTXhsPTEQvF2= M2LNOVJp M3ixVZBienSrYXzsfUBl\WO{ZXHz[ZMhe2:maYXtJJNmdGWwaYTlMYlv\HWlZXSgZZBweHSxc3nz MnjSNlI4OjF6MES=
Primary OPC MnWzRZBweHSxc3nzJGF{e2G7 MnjmNe69VQ>? M{HxfFZpNzJ2aB?= M2D2OZJm\HWlZYOgeIhmKHCncnPlcpRi\2Vib3[gZ4VtdHNiaX6g[YFzdHlvIHHu[EBt[XSnLXHwc5B1d3Orcz;u[YNzd3Orcx?= MlrwNlI4ODd|OEW=
PMNs MWLBdI9xfG:|aYOgRZN{[Xl? NWHmPVJ{PDEQvF2= NGKxR|Q3cA>? MYLEUXNQ NITpb5Jz\X[ncoPl[EB1cGViYX3veY51KG:oIHPs[YF3\WRiY3HzdIF{\S1|IITvJI5m[XJidnXobYNt\SCuZY\lcJM> NWXMWpRNOjJ4OUK1O|c>
A549  MkLGRZBweHSxc3nzJGF{e2G7 MVO1NO69VQ>? MWGxbC=> NVLNXnFbeHKndnXueJMh[XCxcITvd4l{KGmwZIXj[YQh[nliQnHvbJVwe2mmZTDJ MUmyNlY5PzZ|NR?=
AGS Mmf0RZBweHSxc3nzJGF{e2G7 NVnmPJVyOjEQvF2= NHzVXXMyOmh? MmDubY5pcWKrdIOgeIhmKGGldHn2ZZRqd25ib3[gdJJwNWOjc4Dhd4UuOyCrbjDy[ZNxd26|ZTD0c{B1cGViRYTPRYMh\nKjY4Tpc44> Ml:5NlI3QDd|OUi=
shC9  Mn;1RZBweHSxc3nzJGF{e2G7 MnvPNVDPxE1? NHuzd48yPmh? NHXncnJjdHWwdIOgV2hJKGW6cILld5Nqd25iaX6gd4hEQSClZXzsd{BmgHCxc3XkJJRwKGWrdHjldkBRSSCxcjDMVGM> NVm2bFBvOjJ4NEGwPVQ>
primary MEFs NVrl[JVMTnWwY4Tpc44hSXO|YYm= NWThZWZ3OTKq NF\mS5bDqGmwY4LlZZNmeyCndH;wc5Nq\GVvaX7keYNm\CCvaYTvZ4hwdmS{aXHsJI1mdWK{YX7lJIRmeG:uYYLpfoF1cW:w MknDNlI3OTN5Nke=
3T9 MEFs NWfCT2Z5TnWwY4Tpc44hSXO|YYm= NEDLbnMyPmh? NVfsWGdScW6lcnXhd4V{KGO7dH;jbJJwdWViYzDy[Yxm[XOnIHHmeIVzKGW2b4Dvd4ll\S22cnXheI1mdnR? MlO2NlI3OTN5Nke=
3T9 MEFs Mne4SpVv[3Srb36gRZN{[Xl? NU[w[JRHOTiq NVf1NZdDfXC{ZXf1cIF1\XNiaX7peIlifG:{IHPhd5Bie2VvOTDieZQh\G:5boLl[5Vt[XSnczDl[oZm[3SxcjDjZZNx[XOnczDh[pRmeiCndH;wc5Nq\GVidILlZZRu\W62 NIS0UZQzOjZzM{e2Oy=>
MDA-MB-231  NVzxTIdQSXCxcITvd4l{KEG|c3H5 NF3BSmIzOM7:TR?= NXvze2pZPGR? NIL2T2Fz\WS3Y3XzJJRp\SClZXzsJIFxd3C2b4Ppd{BqdmS3Y3XkJIJ6KG2ndH\vdo1qdiC2cnXheI1mdnRid3HzJJNq\26rZnnjZY51dHl? NVG2RWhQOjJ3OUO0OFE>
C6  NUnQOG9iSXCxcITvd4l{KEG|c3H5 M3PqPFEx|ryP M3TiUVI1cA>? M{C4S4Jtd2OtczD0bIUhe3WycILld5NqfmViZX\m[YN1KG:oIITo[UBx\XC2aXTlJI9vKH[rYXLpcIl1gQ>? MoSzNlI2QDh7OEC=
HL-60  NEDYcJpCeG:ydH;zbZMhSXO|YYm= MXuxNFDPxE1? MUOyOIg> M3n4RolvcGmkaYTzJJRp\SClZXzsJIFxd3C2b4Ppd{B{\WynY4Tl[EApMylvbXXueIh6dCEQsj2oNgKHmjZrLXTp[4x2[2:yeYLhco9{cWSnwrC1 MU[yNlU1PjZ4OR?=
HL-60 M2DEdGFxd3C2b4Ppd{BCe3OjeR?= M4nsOFExNThyzszN NET6N|g1cA>? M1zOVYlvcGmkaYTzJHRIUFFvaX7keYNm\CClZXzsJIFxd3C2b4Ppd:Kh MWqyNlUzOzJ{OR?=
BCC Mnq0RZBweHSxc3nzJGF{e2G7 NYrHXFRVPTEQvF2= MnLjNYg> NWnwdWI3cW6qaXLpeJMhTEGWUz3t[YRq[XSnZDDndo94fGhiaX7obYJqfGmxbh?= M3XPUlIzPTF7NEO2
RAW 264.7 NVHUSXRbSXCxcITvd4l{KEG|c3H5 M3PhT|UxNzFyMN88US=> NH2x[IgycA>? Ml;WZ49v[2WwdILheIlwdi2mZYDlcoRmdnRiaX7obYJqfHNiRF;OMYlv\HWlZXSgdnJPSSClbHXheoFo\Q>? MojKNlI1QTF2Mk[=
K562 MX3BdI9xfG:|aYOgRZN{[Xl? MWKyOe69VQ>? MUWybC=> MnL0dJJmfmWwdIOgZZBweHSxc3nzJIlv\HWlZXSgZpkh[29vdILlZZRu\W62IIfpeIgh[W23cnXud4lvKEdiYX7kJHRTSUmO MW[yNlQ5Ozd5Nx?=
SGC-7901 NETaOFhCeG:ydH;zbZMhSXO|YYm= Ml6wNlAh|ryPwrC= NHLjfZUzcA>? MVLheJRmdnWjdHXzJGgzVzMEoH;yJHRPTiEQsT3pcoR2[2WmIHPlcIwh[XCxcITvd4l{KGG|IIflcIwh[XNiY3HzdIF{\S1|IHHjeIl3cXS7wrC= MVSyNlQ4OTV6OR?=
PC3 NY\kUZdvSXCxcITvd4l{KEG|c3H5 M1zSR|Ex|ryP MYO0bC=> NYnrd2ZG[2:3boTldpMh\myjdn;jc5hq\C2rbnT1Z4VlKGOjc4Dhd4UuemWuYYTl[EBieG:ydH;zbZM> MX2yNlQ4OTl5NB?=