Z-VAD-FMK

For research use only. Not for use in humans.

目录号:S7023

Z-VAD-FMK Chemical Structure

Molecular Weight(MW): 467.49

Z-VAD-FMK是一种细胞渗透性的,不可逆泛caspase抑制剂,在THP.1 和 Jurkat T细胞中阻断细胞凋亡的所有特性。

规格 价格 库存 购买数量  
RMB 962.65 现货
RMB 3841.92 现货
RMB 21048.63 现货
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客户使用Selleck生产的Z-VAD-FMK发表文献535篇:

产品安全说明书

Caspase抑制剂选择性比较

生物活性

产品描述 Z-VAD-FMK是一种细胞渗透性的,不可逆泛caspase抑制剂,在THP.1 和 Jurkat T细胞中阻断细胞凋亡的所有特性。
特性 Z-VAD-FMK是研究细胞凋亡的一种关键化合物。
靶点
Pan-caspase [1]
(THP.1, Jurkat T-cells)
体外研究

Z-VAD-FMK(10 mM)作用于THP.1细胞,抑制细胞凋亡。Z-VAD-FMK(10 μM)作用于THP.1细胞裂解液,抑制PARP蛋白酶活性的激活。Z-VAD-FMK(10 mM)作用于完整THP.1和 Jurkat细胞,抑制CPP32加工。[1]Z-VAD-FMK(50 μM)与Camptothecin共处理HL60细胞,废除Camptothecin处理的细胞凋亡形态。Z-VAD-FMK(50 μM)作用于HL60细胞,抑制Camptothecin诱导的DNA分裂。[2]Z-VAD-FMK (50 μM)作用于S2细胞,提高转染细胞的生存百分数从26%提高到63%。[3]Z-VAD-FMK(>100 μM)作用于人类嗜中性粒细胞,增强TNFα-诱导的中性粒细胞凋亡,较低浓度(1-30 μM)时完全抑制TNFα刺激的细胞凋亡。[4]Z-VAD-FMK (10 mM) 作用于早期角膜基质细胞,抑制细胞凋亡。[5]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
GC1a NGTTNYZCeG:ydH;zbZMhSXO|YYm= NYHZ[Yt{PTEQvF2= MWCyOIg> NIXkfGVqdmSrY3H0[ZMh[SCycn;0[YN1cX[nIHXm[oVkfCCjZ3HpcpN1KGW2b4Dvd4ll\Q>? M4nodlI3OTZ7MEe1
HGL5 NF\KNFlCeG:ydH;zbZMhSXO|YYm= NUHXN|BvPTEQvF2= NEf2NngzPGh? NEDFWphqdmSrY3H0[ZMh[SCycn;0[YN1cX[nIHXm[oVkfCCjZ3HpcpN1KGW2b4Dvd4ll\Q>? M3\MUFI3OTZ7MEe1
HepG2 MkS0RZBweHSxc3nzJGF{e2G7 MYeyNO69VQ>? NF;oVZMycA>? MY\heJRmdnWjdHXkJJRp\SCjcH;weI91cWNiaX7keYN1cW:wIH;mJGlKUS1zMNMg MkPENlYyPjR5OUW=
BEL-7402 M4\sU2Fxd3C2b4Ppd{BCe3OjeR?= MX[yNO69VQ>? MUKxbC=> NInyXItifHSnboXheIVlKHSqZTDhdI9xfG:2aXOgbY5lfWO2aX;uJI9nKEmLST2xNOKh NWCyc|hqOjZzNkS3PVU>
CEF M3rwV2tqdmG|ZTDBd5NigQ>? M2qyTlAtOzNuNkesNVAx|ryP M1PnSlE2dWmw MkLu[I94di2{ZXf1cIF1\XNiUGKg[Y57gW2nIHHjeIl3cXS7IITvJFQx97zHIHH0JFExOM7:TR?= NVHKOXFPOjZzMEKzN|k>
SP2/0 NHzoWoJCeG:ydH;zbZMhSXO|YYm= MUOxNFDPxE1? M1HwcFFp NVXHNVBDTE2VTx?= M33HZoJtd2OtczD0bIUh[XCxcITvd4l{KG:oIGPQNk8xKGOnbHzz NGGwWGwzPjB5NEezNi=>
HUVEC-2c M{D2eWFxd3C2b4Ppd{BCe3OjeR?= M373ZVUx|ryP M3P5dlZp NH7aNIll\WO{ZXHz[YQhfGinIH;4MWxFVC2rbnT1Z4VlKGG3dH;wbIFogQ>? MXeyOlAzOTd{OR?=
U1 NH60ZYNCeG:ydH;zbZMhSXO|YYm= NHLqXIsxNTFyMN88US=> MXqybC=> M4K4[pJm\HWlZYOg[JJ2\y2rbnT1Z4VlKGGyb4D0c5NqeyCjbnSgd5Vje2WzdXXueEBJUVZvMTDy[ZBtcWOjdHnvckBqdiCjIHTvd4Uu\GWyZX7k[Y51KG2jbn7ldi=> M1T5PVI2QThyOUSy
ACH-2 NYLBeHI1SXCxcITvd4l{KEG|c3H5 NVnTWnBjOC1{MEFOwG0> M3LVclJp MnXxdoVlfWOnczDkdpVoNWmwZIXj[YQh[XCxcITvd4l{KGGwZDDzeYJ{\XG3ZX70JGhKXi1zIILldIxq[2G2aX;uJIlvKGFiZH;z[U1l\XCnbnTlcpQhdWGwbnXy NWnUSoZOOjV7OEC5OFI>
U1 MojCT4lv[XOnIFHzd4F6 M3jxW|ExOM7:TR?= NHHyWoozcA>? NYOweVVocW6qaXLpeJMh[2G|cHHz[U0{ M2rVTlI2QThyOUSy
A549/V16 NEjZfIFCeG:ydH;zbZMhSXO|YYm= NYG1XY9RPTEQvF2= M{Hke|Fp MkjLdoVxemW|c3XzJHRIN1SPLXnu[JVk\WRiYYDvdJRwe2m| M2HLXVI2QTR4MEOz
SGN Ml\hRZBweHSxc3nzJGF{e2G7 NYLHZVY4OjCvTR?= NWj5TnlHPDiq Mof2bIF{KG6xIHnu[ox2\W6lZTDvckBCUUZuIHPhcJBicW5iZYjwdoV{e2mxbjDvdkBk\WyuIHHwc5B1d3Orcx?= NWXCW3VNOjV6N{S2N|M>
HCT116  NHHZNVlCeG:ydH;zbZMhSXO|YYm= NUjQT3E4PTEQvF2= NEXEUogzcA>? NIL0c4hqdmirYnn0d{B1cGViY3XscEBl\WG2aDDpcoR2[2WmIHL5JGRFXlB? NF23TGMzPTh4OEixPC=>
DTK-SME M4L4PWFxd3C2b4Ppd{BCe3OjeR?= M3[0b|Ux|ryP M2fnO|Jp MV3EUXNQ NVfKd5gyeGG{dHnhcIx6KGmwaHnibZR{KHSqZTDhdI9xfG:|aYOgbY5lfWOnZDDifUBjfXCrdnHjZYlv\Q>? M4TXfVI2QDR|OEm3
HL-60 MnzXRZBweHSxc3nzJGF{e2G7 Ml[wOVDPxE1? MWC0PIg> MX\y[YR2[2W|IHPlcIwh\GWjdHigZ4F2e2WmIHL5JHNMUS2LSTD0doVifG2nboVCpC=> NHTmWW8zPTh{NEC0Ny=>
U937 MlHBRZBweHSxc3nzJGF{e2G7 M4HBe|Ux|ryP NHXjV3k1QGh? M1\SVZJm\HWlZYOgZ4VtdCCmZXH0bEBk[XW|ZXSgZpkhW0uLLVnJJJRz\WG2bXXueOKh M4XmfVI2QDJ2MESz
A549 NGLOfY1CeG:ydH;zbZMhSXO|YYm= NIrDVFgzOCEQvF2= NEfEPXEzPGh? NX3MRnJQemWmdXPld{Bk\WyuIHTlZZRpKGOjdYPl[EBjgSCKRlPQJJRz\WG2bXXueC=> M1zXVVI2Pzl2MUS5
HeLa MVXBdI9xfG:|aYOgRZN{[Xl? M4mzO|Ex|ryP NETW[Vg1QGh? NGXL[Ipl\WOuaX7ld{B1cGVicnH0[UBw\iCjcH;weI9{cXNiZILhcYF1cWOjbHz5 M3LDXlI2Pzd{NUS1
SGC-7901 NYfJOW9oSXCxcITvd4l{KEG|c3H5 NVTzfFlCOjEEoN88US=> Mmq5NYg> MmLubY5pcWKrdIOgeIhmKGOnbHyg[IVifGhiaX7keYNm\CCkeTDvfIFtcXCuYYTpci=> NFXBNIwzPTd4N{C3Oi=>
MCF-7 NV3DNYZOSXCxcITvd4l{KEG|c3H5 M1HmWVEx|ryP NHH6TpEzcA>? M{P2fYlvcGmkaYTzJJRp\SClZXzsJIRm[XSqIHnu[JVk\WRiYomgN2I> MUmyOVczOjFzNB?=
A549 MXPBdI9xfG:|aYOgRZN{[Xl? NUHYUmF7OTBizszN MnfVNlRp MnX4SG1UVw>? MkPLdJJwdW:2ZYOgTGJENXS{ZXH0[YQhSTV2OTDj[YxtKHO3co\peoFtKCZiYYT0[Y52[XSnczD0bIUh[2ynYY\l[EBRSVKSIHX4dJJme3Orb36= M1nEWVI2Pjh|NU[4
U87 M1v4[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHnpcZM2OM7:TR?= NFPScYYycA>? MYny[YNwfmW{czDj[YxtKGe{b4f0bEBnem:vIGTNXkB1emWjdH3lcpQ> MXOyOVY5OTZ4OB?=
Neocortical Neuron NG\NWYVP\XW{b4TvfIlkcXS7IFHzd4F6 NUXXc|lEOTByzszN NIfsT5gycA>? M1fEWoFvfGGpb37pfoV{KEixaXHtbYRmKEFvSX7keYNm\CCQZYXyc5RwgGmlaYT5 Mk\4NlU3PzVyMEG=
Primary human placental cytotrophoblasts NXHoRnVySXCxcITvd4l{KEG|c3H5 NX;ob2hmOzEQvF2= MmHnNlRp NUmyVoFRTE2VTx?= NWDvNJY2emW4ZYLz[ZMhfGinIHnubIljcXSrb36gc4YhOTIQsj3IV2QzKGK7IITybYNtd3OjbtMg MWqyOVY1OjV7Mh?=
MM MX;BdI9xfG:|aYOgRZN{[Xl? NVjjb21mPTEQvF2= NFrqdY4zOG2rbh?= NIfNNodx[XK2bImgbY5pcWKrdIOgV2hMNWmwZIXj[YQhKGOnbHyg[IVifGh? Mnz0NlU2OzByOUi=
DLD1 MoXyRZBweHSxc3nzJGF{e2G7 NV3E[2pWOjEEoN88US=> M2LvdVFp NIiyeVdx[XK2bImgdoV3\XK|ZYOgZ4VtdCCjcH;weI9{cXNiY3H1d4VlKGK7IGfTVFE> MnL3NlU2OjR{NE[=
MDA-MB-231 NUfJRW95S3m2b4TvfIlkcXS7IFHzd4F6 NGnOUHgyOM7:TR?= NVuxUZRKOWh? NH3s[JFifWevZX70d{Bk\WyuIHTlZZRpKGGodHXyJGNJXUFidILlZZRu\W62 NGjlc4IzPTV{MUWwNS=>
MKN28 M{f3cWFxd3C2b4Ppd{BCe3OjeR?= MlHFNVDPxE1? MYqzNI1qdg>? M2n1cGROW09? M4SwcYlvcGmkaYTzJHRPTi4QsTDwcJV{KEOKWD3pcoR2[2WmIHHwc5B1d3Orcx?= NHG0bmIzPTVzM{m2NC=>
HL-60 Mk[4R5l1d3SxeHnjbZR6KEG|c3H5 MluxNVAx|ryP MVOxbC=> NWnDbpE{TE2VTx?= M3XjXeKhcW2ycn;2[ZMhfmmjYnnsbZR6KG:oIGTDUmF{NXS{ZXH0[YQh[2WubIO= MnfDNlU2ODJ7M{K=
AGS M1;POWFxd3C2b4Ppd{BCe3OjeR?= M1HPTVEx|ryP Moe1NYg> M322OZBz\X[nboTzJIN2emO3bXnuMYlv\HWlZXSgZ4xm[X[jZ3Wgc4Yh[2G|cHHz[U0{NCBvODygZY5lKC17IIDyc5RmcW6| NEfFRWQzPTR7MkKxOC=>
A549  MV3BdI9xfG:|aYOgRZN{[Xl? M13JOlEx|ryP M1LEWVI1cA>? MmTUZoxw[2u|IFTNRXMucW6mdXPl[EBkdGWjdnHn[UBw\iClYYPwZZNmNTNiYX7kJHBCWlBiYX7kJIFxd3C2b4TpZ{Bk\WyuIHTlZZRp MVyyOVQ{PDl6OR?=
INS-1 NGjT[5lCeG:ydH;zbZMhSXO|YYm= NIXFXFU2OM7:TR?= Mk\uOog> M3TLVmROW09? MVnk[YNz\WG|ZYOgeIhmKHC{b4DvdpRqd25ib3[g[YFzdHliYYDvdJRwfGmlIHPlcIx{yqB? MorNNlU1OzB6OUe=
Primary hepatocytes  M{S0[mFxd3C2b4Ppd{BCe3OjeR?= NIDTPGM2OM7:TR?= MV6xPIg> NWLkb41lcW6qaXLpeJMh[XCxcITvd4l{KG:oIHjldIF1d2O7dHXzJIlv\HWlZXSgZpkhSWO2IFSgZY5lKFSQRj5OtS=> MlH4NlU1ODd3M{i=
L929-A  NH3heVREgXSxdH;4bYNqfHliQYPzZZk> NXXtZmRJOjEEoN88US=> NXTBNWVqOjSq NUTsZmZPcW6qaXLpeJMhXE6IzsGtbY5lfWOnZDDj[YxtKGSnYYTo NGHaSXEzPTN7OEW0NC=>
L929-N MlrOR5l1d3SxeHnjbZR6KEG|c3H5 M4jablIxyqEQvF2= NGHyT4czPGh? MVTlcohidmOnczDk[YF1cCC4aXGgZZV1d2O{aX7lJHRPTs7zIIDyc4R2[3Srb36= NVTOV3g{OjV|OUi1OFA>
Cytotoxicity Assay NXH2dnRbS2WubDDWbYFjcWyrdImgRZN{[Xl? NGjEblgzOM7:TR?= NVvwV5lxPDiq NHXvXYhxemW4ZX70JG1JVURvaX7keYNm\CClZXzsJIRm[XSq MmW0NlU{QTJzMU[=
COS7 NYDqdJY3U2mwYYPlJGF{e2G7 NXP4N5VOOTEQvF2= NVf3TYN[OjSq MY\pcoNz\WG|ZYOgZ4F{eGG|ZTCzM|ch[WO2aY\peIlmew>? MnH0NlU{QDRyMkW=
COS7 M4PGV2Fxd3C2b4Ppd{BCe3OjeR?= MkP4NVDPxE1? NEPLS4o1QGh? NUXTXXFOeGG{dHnhcIx6KHC{ZY\lcpRm\CCIQ{GwNU1qdmS3Y3XkJINmdGxiZHXheIg> MUmyOVM5PDB{NR?=
A375 NHLkS2ZCeG:ydH;zbZMhSXO|YYm= MoOxN|DPxE1? M4TSU|Jp MnTFdJJmfmWwdIOgeIhmKGS{dXetbY5lfWOnZDDQRXJRKGOuZXH2ZYdm MmPjNlU{PzZzMUW=
A549 MkjqRZBweHSxc3nzJGF{e2G7 Ml\pOVDPxE1? MmLHNlRp NYj5enNUemW4ZYLz[ZMhemmkb4PvcYUh[mmxZ3Xu[ZNqeyCjbnSgZZBweHSxc3nzJINifXOnZDDifUAhS2iran;u[4Ridg>? NEPpN40zPTN2OUe4NS=>
A549 NXuwWIxWSXCxcITvd4l{KEG|c3H5 MkfNNk42NTJ3zszN M4C0c|Fp NETNd4ll\WO{ZXHz[ZMhfGinIIDvdJVt[XSrb36gc4Yh[XCxcITveIlkKGOnbHzzJIRmeGWwZDDvckBkd26lZX70doF1cW:wcx?= MXWyOVM1OjR{Nx?=
 NBL-W-S  M37NWmFxd3C2b4Ppd{BCe3OjeR?= NIDsWnM2OM7:TR?= MoH0NYg> NGTwcJZnfWyueTDy[ZNkfWW|IHPlcIwhfmmjYnnsbZR6KGGodHXyJGdCVlRvNkGgeJJm[XSvZX70 MWeyOVMzOzJ{Mh?=
Caki-1  MmLDRZBweHSxc3nzJGF{e2G7 NYDGfZk{PDEQvF2= NFHNOXk1QGh? NVzuZVNiemWmdXPld{B1cGViboXtZoVzKG:oIFHucoV5cW5iVj3wc5NqfGm4ZTDj[Yxtew>? M1:yT|I2Ojd7MUmx
769-P M4S2S2Fxd3C2b4Ppd{BCe3OjeR?= MmPJOFDPxE1? M4fqSFQ5cA>? M3ewW5Jm\HWlZYOgeIhmKG63bXLldkBw\iCDbn7lfIlvKFZvcH;zbZRqfmViY3XscJM> NEX3eVkzPTJ5OUG5NS=>
H9c2 M3\kUWFxd3C2b4Ppd{BCe3OjeR?= M3PZN|Ux|ryP M4nTcVFp MkDMbY5pcWKrdIOgSG9ZNWmwZIXj[YQh[2G|cHHz[UA{KGGldHn2ZZRqd25iYoX0JI5wfCC2aHWgcI9{eyCxZjDj[Yxtew>? M3Lw[lI2Ojh|OEG5
K562 MmOwRZBweHSxc3nzJGF{e2G7 NWD6Z2k6PTEQvF2= MlroOIg> M3\q[4lvcGmkaYTzJGpi[y2DLXnu[JVk\WRiY3XscEBieG:ydH;zbZM> MVSyOVI1OTZzOR?=
L929 NVLDOYRSSXCxcITvd4l{KEG|c3H5 Mmn1NVDPxE1? MVy2bC=> MWrpcoR2[2W|IH7lZ5JweHSxc3nzJJdqfGhiVF7G M3z5OVI2OTl3Nk[w
A549 MXHBdI9xfG:|aYOgRZN{[Xl? MW[xNO69VQ>? MXOzbC=> NGrWfWNz\WS3Y3XzJINmdGxiYYDvdJRwe2m|IHPheZNm\CCkeTDQVXE> NVnzblVXOjVzNkG2PVk>
MCF-7 MXrBdI9xfG:|aYOgRZN{[Xl? MUSyNO69VQ>? M3LneFJp NGD5O5Vl\WO{ZXHz[ZMhU0SULYPpVm5CNWmwZIXj[YQh[XCxcITvd4l{ NHLW[44zPTF6MkK0NC=>
OS MUTBdI9xfG:|aYOgRZN{[Xl? NVjsbXRTOjBxNEFOwG0> MXi3Nog> NEDoPZRqdmirYnn0d{BQWyClZXzsJJZq[WKrbHn0fUBz\WS3Y4Tpc44h[nliQ{[gZ4Vz[W2rZHW= M13NUVI2OTV{M{m5
HUVECs Ml7rRZBweHSxc3nzJGF{e2G7 M4OyVVEx|ryP NUDLRXZGOmh? MUpCpIlvcGmkaYTzJIFxd3C2b4Ppd{BidmRiZnHjbYxqfGG2ZYOgZZV1d3CqYXf5JIlvKESHTm[yMYlv\mWldHXkJGhWXkWFcx?= MnjiNlUyOzh5MEO=
EA.hy926 MXTBdI9xfG:|aYOgRZN{[Xl? NWH3T|dQOTEQvF2= MWiybC=> M3e5VeKhcW6qaXLpeJMh[XCxcITvd4l{KGGwZDDmZYNqdGm2YYTld{BifXSxcHjh[5khcW5iRFXOWlIucW6oZXP0[YQhTUFwaIm5NlY> MnOwNlUyOzh5MEO=
Ebs M3;vWGFxd3C2b4Ppd{BCe3OjeR?= NF2wNVUyOC1zMEFOwG0> M1zpbVI1cA>? M{PNN:KhVU2WUzDn[Y5memG2aX;uJJJifGViZHXjdoVie2WmIHHzJJRp\SClb37j[Y51emG2aX;uJI9nKHpvVlHEMoZucyCrbnPy[YF{\WR? NV7qV41VOjVzM{S4NVc>
Jurkat NFmwSW5CeG:ydH;zbZMhSXO|YYm= MUKyNO69VQ>? MXKyOIg> MYXEUXNQ MoHXdIFzfGmjbHz5JIlvcGmkaYSgZ4VtdCCmZXH0bEBw\iCMdYLrZZQh[2WubIOgbY5lfWOnZDDifUAyODB3OD3GOEBkd22kaX7l[EB4cXSqIG\QReKh MlrWNlUyOjB5MkO=
K562 MYHBdI9xfG:|aYOgRZN{[Xl? M1Hwe|AvOS1zzszN NG\E[5EycA>? NHz5fGVqdmirYnn0d{BkdGWjdnHn[UBw\iCKU2C5NEBqdiCjIHTvd4Uu\GWyZX7k[Y51KG2jbn7ldi=> NFO3cI8zPTFzOUG4PC=>
IMR-32 MlHURZBweHSxc3nzJGF{e2G7 NGnOPXI1OMLizszNxsA> M1fERVJp Mkm2[IVkemWjc3WgbY4h[XCxcITveIlkKGOnbHzzJINwdXCjcnXkJJRwKFRvMjD0c5hqdg>? M1vUS|I2ODh2N{W1
RPMI 8226 M2\4[GFxd3C2b4Ppd{BCe3OjeR?= NXW2OId3OTByzszN MoH5NYg> NIf1UnFidG2xc4SgZ49ueGyndHXsfUBjdG:la4OgZ4VtdCCmZXH0bEBk[XW|ZXSgZpkhdmWlcn;zeIF1cW5vMR?= M{jsTlI2ODN5OEWx
U266  MnvyRZBweHSxc3nzJGF{e2G7 NH7Yc2IyODEQvF2= M1\PVFFp MWLwZZJ1cWGubImgZoxw[2u|IHPlcIwh\GWjdHigZ4F2e2WmIHL5JI5m[3Kxc4TheIlvNTF? MV[yOVA{Pzh3MR?=
H929  Mn7YRZBweHSxc3nzJGF{e2G7 MknYNVAx|ryP MlLRNYg> MX7wZZJ1cWGubImgZoxw[2u|IHPlcIwh\GWjdHigZ4F2e2WmIHL5JI5m[3Kxc4TheIlvNTF? MmCzNlUxOzd6NUG=
MM.1S  NUnj[|FoSXCxcITvd4l{KEG|c3H5 MkfXNVAx|ryP MXmxbC=> NF:0eGFm\m[rY3nlcpRtgSCycnX2[Y51eyC|b4Lh[oVvcWJvaX7keYNm\CClZXzsJIRm[XSqIHPvcYJqdmVid3n0bEBv\WO{b4P0ZZRqdi1z NVm2e45XOjVyM{e4OVE>
C6 M1PBT2Fxd3C2b4Ppd{BCe3OjeR?= MnnmOVDPxE1? M2rLSlQ5cA>? MUPwdoV3\W62czD0bIUhdG:|czDv[kBk\WyuII\pZYJqdGm2eTDjZZV{\WRiYomgdJJm\26nbn;sc45m NVXURo5WOjVyMUO0O|k>
AGS M3P6VGFxd3C2b4Ppd{BCe3OjeR?= NXTtRWxIPTEQvF2= MoXiNlRp NWPLfYdP[WKxbHnzbJMh|rJvbHHwZYNpd26nLXnu[JVk\WRiY3XscEBl\WG2aDDhcoQhcW6qaXLpeIVlKGe{b4f0bC=> NWnYO2pVOjVyMEm2PVg>
HeLa  MkHORZBweHSxc3nzJGF{e2G7 NFn4fmU1OM7:TR?= MUWyOIg> MnLHbY5pcWKrdIOgeIhmKGmwY4LlZZNm\CCjcH;weI9{cXNiaX7keYNm\CCkeTDzbXJPTjF{MR?= NWfnUGRpOjR7Mki2PFU>
THP-1  M2HaZWFxd3C2b4Ppd{BCe3OjeR?= NGfCcFAyOM7:TR?= M2LxblFp NUX4dmxYemWmdXPld{BieG:ydH;zbZMhcW6mdXPl[EBjgSCDTFGtV2RVyqB? M3HtV|I1QTJ|NkWz
P815  NV2xepFpSXCxcITvd4l{KEG|c3H5 NVTXeHlKOTByINM1US=> NVjiSW1tOTKq MnzFSG1UVw>? MV\pcohq[mm2czD2bZJ2ey2rbnT1Z4VlKGGyb4D0c5Nqew>? MYSyOFkzOzJ5Mx?=
HCT116 M3;oXmFxd3C2b4Ppd{BCe3OjeR?= MUmyNO69VQ>? MnjtNlRp M1jN[IFjem:pYYTld{Bw\iCWUT3pcoR2[2WmIHHwc5B1d3Or MVWyOFg6ODR2OR?=
SW1116  NGTtdXJCeG:ydH;zbZMhSXO|YYm= M{DmcVExKML3TR?= NEPpUVIycA>? NHHHTZVFVVOR NVXQNYg{emW|dILhbY5{KGOnbHygZZBweHSxc3nzJIlv\HWlZXSgZpkh\2WoaYTpcoljKHCudYOg[IVkcXSjYnnu[S=> M2LCR|I1QDd2Mki2
LOVO MYfBdI9xfG:|aYOgRZN{[Xl? NFrlR2gyOCEEtV2= NXexeVRmOWh? MV3EUXNQ M3LwZZJme3S{YXnud{Bk\WyuIHHwc5B1d3OrczDpcoR2[2WmIHL5JIdm\mm2aX7pZkBxdHW|IHTlZ4l1[WKrbnW= NGT1dWkzPDh5NEK4Oi=>
SNU449  NX3hbJZtSXCxcITvd4l{KEG|c3H5 MX:yNO69VQ>? M3LxflQ5cA>? MWjEUXNQ MXjk[YNz\WG|ZYOgcYlTNTR3MT3pcoR2[2WmIHHwc5B1d3SrYx?= MlXWNlQ5PDF4M{i=
Caco-2 NHfUO4xCeG:ydH;zbZMhSXO|YYm= NFrXUZk1OOLCid88US=> NH7t[pU1cA>? M1XZTpBz\X[nboTzJHNVNTdvaX7keYNm\CCcTz2xJINp[W6pZYOgZY5lKFSHUjDkdo9x NHTj[3ozPDh{MkG4Ny=>
macrophage MlTER4VtdCCYaXHibYxqfHliQYPzZZk> NUPpfJJuOC1{MEFOwG0> NGj2dlczPGh? MlrQbY5lfWOnczDUUmYuKGGwZDDSbZA{NWSncHXu[IVvfCCwZXPyc5B1d3OrczDpckBu[WO{b4DoZYdm NEj5bZIzPDd7OUW2OS=>
AGS  M1HISWFxd3C2b4Ppd{BCe3OjeR?= MXuyNO69VQ>? MoPRNVJp MlLmSG1UVw>? MX\y[YR2[2W|IITo[UBqdmS3Y4Tpc44hd2ZiYYDvdJRwe2m|IHnuJJJme3CxboPlJJRwKHSqZTDFeG9C[yCocnHjeIlwdiCrbjDhJIRwe2VvZHXw[Y5l\W62IH3hco5meg>? NYXnTI5TOjR5OEm3NFM>
LCC9  MmXXR4VtdCCYaXHibYxqfHliQYPzZZk> MXOxNFDPxE1? MVe1[C=> M4CwfoJtd2OtczDj[YxtKGSnYYToJIlv\HWlZXSgZpkh[2:vYnnuZZRqd25iTEG3JIFv\CClaHzvdo9yfWmwZR?= M1S3c|I1Pzh3MkW2
U937  M4ra[45m[3KxcITvd4l{KEG|c3H5 MXexNOKh|ryP M13uZ|MxyqCvaX6= NYm0NIhGcW6mdXPld{Bv\WO{b4D0c5NqeyClb33ibY5mKHerdHigWG5H MmTxNlQ4PzN5NU[=
T cell M4[yeWNmdGxicILvcIln\XKjdHnvckBie3OjeR?= M2KzTlAuOTByzszN MXK3Nog> MWHJR|UxRTdyIN88UUwhcW6qaXLpeJMh[W62aT3DSFMucW6mdXPl[EBVKGOnbHygdJJwdGmoZYLheIlwdiCrbjDQRm1Eew>? MoLiNlQ4Pjh5MEe=
HeLa  M3nIbGFxd3C2b4Ppd{BCe3OjeR?= MmriOVDPxE1? MoLQO|Jp NWHPSZZxTE2VTx?= M3v0W5Bz\X[nboTzJIFxd3C2b4Ppd{BqdmS3Y3XkJIJ6KGOxbYDveY5le8LiMfMAl|U> M1\L[lI1PzV2N{i2
HeLa  NIrodIRCeG:ydH;zbZMhSXO|YYm= M1rvTFExOM7:TR?= MnXtNlRp Ml:wd5VxeHKnc4Pld{Bz[XSnIH;mJINmdGxiZHXheIghcW6mdXPl[EBjgSCxdnXy[ZhxemW|c3nvckBw\iCJNUnTJI9zKEd5MWKgdFE2OGeudXXkxsA> M1[zb|I1PzJ{NE[4
IEC-6  NYXWdW5mSXCxcITvd4l{KEG|c3H5 M1HxR|Ex|ryP MVqyOIg> NXm5XYxxeHKndnXueJMhXGOmQT3pcoR2[2WmIHPhd5Bie2VvMzDjcIVifmGpZTDhcoQh|rJvY3H0[Y5qdiCmZXfyZYRifGmxbh?= NHj0emMzPDdzMUW3NS=>
HCT116 NWLwO3F6SXCxcITvd4l{KEG|c3H5 NWrjd|Z6OjEQvF2= NELxZ3IzPGh? NWLJVWxWcW6qaXLpeJMhfGinIHPlcIwh[XCxcITveIlkKGmwZIXj[YQh[nliWVzUNlA2 Mnj5NlQ4OTN6MUK=
L02 MYrBdI9xfG:|aYOgRZN{[Xl? MVeyNO69VQ>? MXGxbC=> Mon3dJJmfmWwdIOgeIhmKGOnbHygZZBweHSxc3nzJIlv\HWlZXSgZpkhVUWKUB?= M4\IdFI1PzB4NE[x
A375 NWfwc25zSXCxcITvd4l{KEG|c3H5 NF;WdpMzOM7:TR?= MWOyOIg> MmTEdoV3\XK|ZYOg[IlkcXS{aX7vcoUhSi2rbnT1Z4VlKGGyb4D0c5Nqew>? MlqwNlQ3QTlzMUG=
HDPC M2juUWFxd3C2b4Ppd{BCe3OjeR?= MYm1NOK2VQ>? MmL6NlRp NYjzZ|hmcW6qaXLpeJMhVk9vaX7keYNm\CCjcH;weI9{cXN? MknNNlQ3OzR3OUO=
A549 MUXBdI9xfG:|aYOgRZN{[Xl? M1zWU|UxyrWP MWiybC=> Mo\wSG1UVw>? MlfYdJJmfmWwdIOgeIhmKGi7cH;kbZBtd2mmIFTORUBkd262ZX70JJBp[XOnIHnu[JVk\WRiYomgZ4VxcGGub3Podo9ucW5? MoC4NlQ2QDhzM{W=
 BV-2 NXT1clhzSXCxcITvd4l{KEG|c3H5 NXPzV4tUOjEQvF2= M1HLVFJp NXq4W4tpe3WycILld5NmeyCXVj3pcoR2[2WmIHPodo9u[XSrbjDlfJRzfXOrb36gZY5lKGSrbHH0bY9vKG:oIITo[UBvfWOuZXHyJIVvfmWub4Dl NYfzTlQzOjR3NUixNVg>
HT-29  NIXzTpZCeG:ydH;zbZMhSXO|YYm= M1PDcVUx|ryP NV3hPJcxPDiq MWficI9kc3NidHjlJIFxd3C2b4Ppd{BqdmS3Y3XkJIJ6KGujZX3w[oVzd2x? NUj4SIhkOjR3NEmxO|U>
A549 MoHyRZBweHSxc3nzJGF{e2G7 NY\rcnF4Pc7:TR?= NWDSPVF6OjSq M{jBbpN2eHC{ZYPz[ZMhPmYEoDjCT|ExODRyKT3pcoR2[2WmIHHwc5B1d3Orc9Mg MVSyOFUzQTh5MR?=
MIA-PaCa-2 M1qxVGFxd3C2b4Ppd{BCe3OjeR?= NFPNV|czPGh? NIDZ[4djdG:la4OgZ4xm[X[jZ3Wgc4Yh[2G|cHHz[U0{KGmwZIXj[YQh[nliYn;0bEBCNTR2M{[1OEBidmRicHHjcIl1[XinbB?= NEfWdVkzPDVzMEm5Ni=>
Caki-1 NF;scotCeG:ydH;zbZMhSXO|YYm= NYi2d3hDOjEQvF2= M2nlWlFp MkK5bY5pcWKrdIOgV2NRNWmwZIXj[YQh[XCxcITvd4l{ NHLFeGkzPDVyNE[4NS=>
CLL NEXsNoNCeG:ydH;zbZMhSXO|YYm= M{Tsb|I2|ryP M4f4c|Fp NHfp[|Zx[XK2aXHscJkh[myxY3vzJG1NVjJ{M{itbY5lfWOnZDDj[YxtKGGyb4D0c5Nqew>? M3HFNFI1PDZ5NkO0
SGC-7901 NXXrXXhDSXCxcITvd4l{KEG|c3H5 M1vzVFEx|ryP MmLDNlRp NU\zOWVweHKxbX;0[ZMhfGinIFPHTWkucW6qaXLpeIVlKGOnbHyg[5Jwf3SqIHnuJHNISy15OUCxJINmdGy| MYOyOFQ2PDR6OB?=
k1735 MUHBdI9xfG:|aYOgRZN{[Xl? NGq5WI4zOOLCid88cS=> MlPnOIg> M1:zZ4lvcGmkaYTzxsBU[Wyvb37lcIxiNWmwZIXj[YQh[XCxcITvd4l{ MYSyOFQ2OTFzNh?=
HaCaT  M3j6[2Fxd3C2b4Ppd{BCe3OjeR?= NIT1RXoyODEQvF2= MoPONYg> NYnqTI03[my3boTzJHVXSi2rbnT1Z4VlKGGyb4D0c5NqeyCrbjDIZWNiXCClZXzsdy=> NYTSXo9mOjR|NU[5PVc>
podocytes MYfBdI9xfG:|aYOgRZN{[Xl? NX\n[4NPOjByzszN NF74UXM3cA>? NHnLcYtqdmirYnn0d{BieG:ydH;zbZMhcW6mdXPl[EBjgSB|LEStSGdG Mn;RNlQ{Ozd5N{e=
 KB NYXvdpROSXCxcITvd4l{KEG|c3H5 M3;aZlUx|ryP M33KWVI1cA>? NInRWGVqdmirYnn0d{BNcWOxLVGtbY5lfWOnZDDjZZNx[XOnLUOgZY5lKFCDUmCgZYN1cX[jdHnvci=> M3nySVI1OzN5NEmy
 HepG2  M3LDd2Fxd3C2b4Ppd{BCe3OjeR?= MVOxNO69VQ>? MnvBNlRp NVTEbIl1emWmdXPld{B3cW2nboTpckBkdGWjdnHn[UBk[XW|ZXSgZpkhVFCV NV;hdFY4OjR|MkW4NVY>
fetal rat lung fibroblasts  NGflWWZMcW6jc3WgRZN{[Xl? NIDGR5c5OM7:TdMg MXSxbC=> NELUbGRqdmirYnn0d{BE[XOyYYPlMVMh[WO2aY\peJnDqA>? Ml;sNlQ{OTRzM{W=
PDL fibroblasts NFfiV5BMcW6jc3WgRZN{[Xl? MUK4NO69VcLi NXfzXJlUOWh? NXnJdldscW6qaXLpeJMhS2G|cHHz[U0{KGGldHn2bZR6yqB? MX[yOFMyPDF|NR?=
MB49 M{HhOWFxd3C2b4Ppd{BCe3OjeR?= MoPkNlDPxE1? MX6xbC=> NETNcWdz\X[ncoPld{BEVS2rbnT1Z4VlKGOnbHyg[IVifGh? M2XHTFI1Ojh{NEOz
5637 MkDGRZBweHSxc3nzJGF{e2G7 NVfvdolDOjEQvF2= NVnjdlhyOWh? NFP0fVlz\X[ncoPld{BEVS2rbnT1Z4VlKGOnbHyg[IVifGh? NFH3WlEzPDJ6MkSzNy=>
A549  NV3HR5pkSXCxcITvd4l{KEG|c3H5 MWSxNFDPxE1? MVW0PIg> MoXUd5VxeHKnc4Pld{B1cGViYYDvdJRwe2m|IHPheZNm\CCkeTDwbZBmemmwZdMg NYLoVlVHOjR{N{KyNFE>
MCC-2 MVPBdI9xfG:|aYOgRZN{[Xl? M4nzOFIxKM7:TR?= MoPBOog> MoHoSG1UVw>? NFHI[pFjdG:la4OgbY5lfWOnZDDifUB{fGG3cn;zdI9zcW6nIHHwc5B1d3OrczDj[YxtKGSnYYTo MoeyNlQzPjJ4NUi=
ADF NXfz[pdpSXCxcITvd4l{KEG|c3H5 MWC0NO69VQ>? MWq2bC=> Mm\wbY5pcWKrdIOgZZBweHSxc3nzJIlv\HWlZXSgZpkh[2inbX;0bIVz[XC7IIDseZMhYm6FbEK= NFi1dFEzPDJ{OEKzNi=>
 U373  NEPJXZJCeG:ydH;zbZMhSXO|YYm= M4PaSVQx|ryP NWTEcI04Pmh? M4rlcolvcGmkaYTzJIFxd3C2b4Ppd{BqdmS3Y3XkJIJ6KGOqZX3veIhmemGyeTDwcJV{KFqwQ3yy MmXtNlQzOjh{M{K=
RKO-HIPK2i NGTPfW9CeG:ydH;zbZMhSXO|YYm= NF7pVlA1OM7:TR?= NXrRW3ptPmh? MYXpcohq[mm2czDhdI9xfG:|aYOgbY5lfWOnZDDifUBkcGWvb4To[ZJieHlicHz1d{BbdkOuMh?= MWCyOFIzQDJ|Mh?=
HEC-1B M3HEbWFxd3C2b4Ppd{BCe3OjeR?= MUiyNO69VQ>? NUPOWGgxOWh? NX\CZ4hmemWmdXPld{BVWC2rbnT1Z4VlKGGyb4D0c5Nqe8LiY3HzdIF{\S1|IHHu[EBk[XOyYYPlMVk> MVmyOFIyOzN3OB?=
4T1 MYTD[YxtKF[rYXLpcIl1gSCDc4PhfS=> M4OwUlIvPS1zMN88US=> M3q2WlRp NF\Yc5NFVVOR MV;y[ZNkfWW|IITo[UBkgXSxdH;4bYNqfHlib3[gOHQyKGOnbHzzJIlv\HWlZXSgZpkhW1CGVDDpckBiKGOxbnPlcpRz[XSrb36g[IVx\W6mZX70JI1idm6nch?= MXOyOFIxPjF4MR?=
OS  M4PoS2Fxd3C2b4Ppd{BCe3OjeR?= MnnONlDPxE1? MYW0bC=> NIrTWXBqdmirYnn0d{B1cGViY3XscEBl\WG2aDDjZZV{\WRiYomgVGRV NEK5S5kzPDJyNEmzOy=>
RPE NXG5WnFqSXCxcITvd4l{KEG|c3H5 MX[xNFDPxE1? NH;vSFc1QGh? NF7yO3Rx[XK2aXHscJkhcW6qaXLpeJMhfGinIHPhcJBicW5vMTDhcoQhNTJiYXP0bZZifGmxbjDhd{B4\WyuIHHzJJRp\SClYYPwZZNmKGGldHn2ZZRqd25? MUGyOFIxOjB3Mh?=
UD29a MV;BdI9xfG:|aYOgRZN{[Xl? MmCxOVDPxE1? NH;rZnIzPGh? NWDlNldlcW6qaXLpeJMhfGinIHPlcIwh\GWjdHigZ4F2e2WmIHL5JG5WXDN? NHzyTGczPDF7MEW3OC=>
SH-SY5Y  MYPBdI9xfG:|aYOgRZN{[Xl? NGfSToEyOM7:TR?= MVuyOIg> NHjoe2xifHSnboXheIV{KGOjc4Dhd4Uh[WO2aY\heIlwdiCjbnSgZ4VtdCCmZXH0bEBqdmS3Y3XkJIJ6KEiQRT2ySGc> NXHmSVFCOjRzNEW0OlM>
HeLa  MmflRZBweHSxc3nzJGF{e2G7 MXqxNE8zOM7:TR?= NIfrdIwzPGh? NGPmcIJqdmirYnn0d{B1cGViYXP0bZZqfHlib3[geIhmKG2jan;ybZR6KG:oIITo[UBu\W2kZYLzJI9nKHSqZTDjZZNx[XOnLX\hcYltgQ>? MlXTNlQyOzd{Nk[=
SCCVII  NXy5TmdVSXCxcITvd4l{KEG|c3H5 NXfGcXJ2OjYQvF2= NFz4ZXAycA>? NG\xPJBqdmirYnn0d{B1cGViY3XscEBscWyuaX7nJIFnfGW{IHThd4F1cW6rYh?= M2PRblI1OTJ4NE[0
RAW 264.7 MmHORZBweHSxc3nzJGF{e2G7 M{fKOlIx|ryP MVixPIg> NEi5NXFqdmO{ZXHz[ZMhVEN|LVnJM:6zNWGldHnuJJJifGmxIHPvcZBiemWmIITvJGVEXFZvTV;TJJRz\WG2bXXueEBwdmy7 Ml\2NlQyOTZ5MEe=
A549  NH7OeW5CeG:ydH;zbZMhSXO|YYm= M2S2cFIvPc7:TR?= NX30c4N6OjSq MX\k[YNz\WG|ZYOgc5Jq\G:waX6tbY5lfWOnZDDheZRweGijZ4mgZZMhf2WubDDhcoQhVG:|czDv[kDPnM,KbTDhcJNwKG:lY4XydoVlKGS3cnnu[{BifXSxcHjh[4lkKHC{b3Pld5M> NVTaOYg{OjRzMEK1NlI>
UM-SCC-10A  NYLWNFB{SXCxcITvd4l{KEG|c3H5 M2LTVFUxyrWP MmfqNog> NVPPcHZlemWmdXPld{BieG:ydH;zbZMhcW6mdXPl[EBjgSCqaXfoMYRwe2ViaYPvZYxidnSxbHHjeI9v\Q>? MorVNlQxQTh5NUO=
BGC-823 MVPBdI9xfG:|aYOgRZN{[Xl? NHz4d3oyOCEQvF2= MnHsNlRp NGPaXmZz\WS3Y3XzJJRmfHKjbnTybY5mNWmwZIXj[YQh[XCxcITvd4l{yqB? NVzWcnNtOjRyOUi1NVE>
Nalm-6  M4rjfWFxd3C2b4Ppd{BCe3OjeR?= MkfoNlDPxE1? NF;ndng1cA>? NHjTO5lqdmirYnn0d{Bk[XOyYYPlMVgh[W6mIHPhd5Bie2VvMzDhZ5RqfmG2aX;uJIFv\CCSQWLQMVEh[2ynYY\h[4U> MV2yOFA{QTl4Nx?=
KHOS  NHiwPJZCeG:ydH;zbZMhSXO|YYm= NFW4PFI1OM7:TR?= NIm0UWYzPGh? NF74c2JjdG:la4OgeIhmKGmwY4LlZZNm\CClbHXheoFo\SCxZjDjZZNx[XOnLUOgZY5lKFCDUmCgbY5lfWOnZDDifUBDSk2GM9Mg MmTSNlQxOjV|NkG=
G292 NGXLe3RCeG:ydH;zbZMhSXO|YYm= MWm0NO69VQ>? MVWyOIg> M{jLbIJtd2OtczD0bIUhcW6lcnXhd4VlKGOuZXH2ZYdmKG:oIHPhd5Bie2VvMzDhcoQhWEGUUDDpcoR2[2WmIHL5JGJDVUR|wrC= MlfyNlQxOjV|NkG=
MG-63 MVPBdI9xfG:|aYOgRZN{[Xl? MV60NO69VQ>? NGDFNIszPGh? NFzm[lJjdG:la4OgeIhmKGmwY4LlZZNm\CClbHXheoFo\SCxZjDjZZNx[XOnLUOgZY5lKFCDUmCgbY5lfWOnZDDifUBDSk2GM9Mg MnjwNlQxOjV|NkG=
EBV-transformed B cells MWDBdI9xfG:|aYOgRZN{[Xl? NHXRWWMzOM7:TR?= M4jDW|Jp M4LwZmROW09? M2OxcYJtd2OtczDhcpRqNUOGOECgZY5lKGGwdHmtR2Q5PiCjboTpZo9lgS2rbnT1Z4VlKGGyb4D0c5Nqew>? NYTmPJRwOjRyMEi2Nlg>
IM-9 B M4\pSWFxd3C2b4Ppd{BCe3OjeR?= NV\CfJBZOjEQvF2= NVrubFRJOmh? M3PUfGROW09? M1TuS4Jtd2OtczDhcpRqNUOGOECgZY5lKGGwdHmtR2Q5PiCjboTpZo9lgS2rbnT1Z4VlKGGyb4D0c5Nqew>? M{XpTFI1ODB6NkK4
CNE1 MlPuRZBweHSxc3nzJGF{e2G7 MkG0NlDPxE1? MYW0PIg> M13LTIJtd2OtczDMT{1CNWmwZIXj[YQh[XCxcITvd4l{ MlX5NlM6QDVyMkm=
CNE2 MUXBdI9xfG:|aYOgRZN{[Xl? NUi1NG5WOjEQvF2= MVS0PIg> NVWwbpA4[myxY3vzJGxMNUFvaX7keYNm\CCjcH;weI9{cXN? NVe1Und[OjN7OEWwNlk>
HL-60 MYrBdI9xfG:|aYOgRZN{[Xl? MmGxOVDDvU1? M2fGdFFp M4jrUWROW09? MWXpcohq[mm2czDhdI9xfG:|aYOgbY5lfWOnZDDifUBDSTF2NR?= NUP1NopoOjN7NEi3OVE>
L929 NHrZOGZCeG:ydH;zbZMhSXO|YYm= Mle1NU4zPeLCk{ZCpO69VcLi NWXnTVJNOjSq M3TWUYF2\22nboTzJHRPTs7zLXnu[JVk\WRibnXjdo9xfG:|aYOgZY5lKGG3dH;wbIFogQ>? MWOyN|k1OTd4OR?=
Jurkat M{\yTmNmdGxiVnnhZoltcXS7IFHzd4F6 M1zHeVLPxE1? MWe0bC=> M3Gzb5JmfmW{c3XzJIdzd3e2aDDpcohq[mm2aX;uJIFv\CEQsj3jZZRmdmmwIHTlZ5Jm[XOnIHL5JGhUNUGVQR?= MlPMNlM5QTZyNkG=
RAW264.7  NEPKfmZCeG:ydH;zbZMhSXO|YYm= NFT3WpYyOCEQvF2= M2DQTFI1cA>? MUHk[YNz\WG|ZYOgeIhmKGGyb4D0c5NqeyCrbnT1Z4VlKGK7IFfB NHez[mkzOzh{MEKwNy=>
A431  MYfLbY5ie2ViQYPzZZk> MVK0NO69VQ>? M4X5OlJp MVzicI9kc3NiZnnz[ZRqdi2rbnT1Z4VlKGOuZXH2ZYdmKG:oIHPhd5Bie2W|IHHu[EBRSVKS MVyyN|gxODB3OB?=
Jurkat NGXVXohE\WyuIG\pZYJqdGm2eTDBd5NigQ>? NGfQS5czPS1zMEFOwG0> MlPEOog> NY\JNJNFcW6qaXLpeJMhgi2IQT3DUWsucW6mdXPl[EBk\WyuIHTlZZRp NHTYR20zOzl|M{WzNi=>
COS-7  M3n6cmZ2dmO2aX;uJGF{e2G7 MnzFOVDDvU1? Mk\qNlRp MljTZYZn\WO2czD0bIUheHKxY3Xzd4lv\yCxZjDBWG4yeyC5aYToJJBwdHmTIITyZYN1ew>? MUiyN|k{OzJyOB?=
CAL27 NEPUT5VCeG:ydH;zbZMhSXO|YYm= NFvySmoyOCEQvF2= NFPiV|UzcA>? M2TteJN2eHC{ZYPz[ZMhS3W{LV7Qd{1z\WS3Y3XkJJZq[WKrbHn0fUBjgSC3cDD0c{A6OCV? NVeyTXoxOjN7MUezPVY>
THP-1  M2PFcmFxd3C2b4Ppd{BCe3OjeR?= NUDrZXJXOTBvNUFOwG0> NYrKWnZsOmh? MoXJbY5pcWKrdIOgZZBweHSxc3nzJIlv\HWlZXSgZpkhfHKrcITvcIll\Q>? NUTucIh3OjN7MECyPVk>
K562 NGfW[HJCeG:ydH;zbZMhSXO|YYm= NWWwNVZ{OjEQvF2= NUfQdmhvPDiq MnHDbY5pcWKrdIOgZZBweHSxc3nzJIlv\HWlZXSgZpkhPC2PVR?= MWOyN|g4Pjh{Nh?=
HL-60 MoPhRZBweHSxc3nzJGF{e2G7 MYSxNFDPxE1? NFq1Xm0zPGh? Mlu4bY5pcWKrdIOgZZBweHSxc3nzJIlv\HWlZXSgZpkh[WKrZYThcoUh\Gm2ZYLw[Y5me8Li Mk[4NlM5PjV5N{i=
HeLa  M2mwVGFxd3C2b4Ppd{BCe3OjeR?= MkXUNlDPxE1? M13YXFJp MmnJbY5pcWKrdIOgSG1OWCCrbnT1Z4VlKGGyb4D0c5Nqew>? NVvUfGt2OjN6NkO5OlY>
U251 NH3lRZJCeG:ydH;zbZMhSXO|YYm= NHjqXoEzOM7:TR?= NYrBWWJ1OjSq NFz5S3lqdmirYnn0d{Bk[XO2aXPpckBqdmS3Y3XkJGczN01icHjhd4Uh[XK{ZYP0JIFv\CCjcH;weI9{cXN? M{PYR|I{QDF4OEG2
HL-60 MUPBdI9xfG:|aYOgRZN{[Xl? MonGOVDDvU1? NH7kbFQ1cA>? M2\kTYJtd2OtczD0bIUh[2ynYY\h[4Uhd2ZiY3HzdIF{\S1|LDCtPUwh[W6mIGDBVnAhcW6mdXPl[EBjgSB4cx?= M1X3VVI{QDB2N{C2
Ec-109 M3S2ZWFxd3C2b4Ppd{BCe3OjeR?= M2nHe|ExKM7:TR?= M3LwVVQ5cA>? NU\qTo1iemWycnXzd4V{KFCHLX3l[IlifGWmIFXjMVExQSClZXzsJIFxd3C2b4Ppdy=> NWPRZWIyOjN5OEK2OFE>
RKO M4fafGNmdGxiVnnhZoltcXS7IFHzd4F6 NFTWUmoyOCEQvF2= M16zflI1cA>? MVfpcohq[mm2czD0bIUh\GWlcnXhd4Uhd2ZiY3XscEB3cWGkaXzpeJkh[2G3c3XkJIJ6KESDQh?= NGK5fJkzOzd3OEC2OC=>
T98G MU\D[YxtKF[rYXLpcIl1gSCDc4PhfS=> MmDZNU0yODEQvF2= MXKyOIg> MoXpbY1xem:4ZYOgZ4VtdCC4aXHibYxqfHliY3;0doVifG2nboSge4l1cCCWUx?= NGTtOFQzOzd4OUK3OS=>
Jurkat NH;uPWNE\WyuIG\pZYJqdGm2eTDBd5NigQ>? M2e1R|ExOC1{MEFOwG0> NVXURVRoOjSq NX;TUFRwcW6qaXLpeJMhUGGDNDDpcoR2[2W|IHHwc5B1d3OrczDk[ZBmdmSnboSgc4Yh[2:wY3XueJJifGmxbtMg MkTGNlM4OzJ2OEG=
Molt-3  Mn;IRZBweHSxc3nzJGF{e2G7 NVrQVVlYPTEQvF2= NIXrSoczcA>? NHr0cHJz\WS3Y3XzJI1mdGG2b37pck1qdmS3Y3XkJIFxd3C2b4Ppdy=> NYnCOIFvOjN5MkWwNVM>
hMSC12 NFXte45CeG:ydH;zbZMhSXO|YYm= NYnyeFNvOTByzszN NHnOcnU1\A>? MkP3bY5pcWKrdIOgc5N1\W:pZX7pZ{BkfWy2dYLlMYlv\HWlZXSgZ4VtdCCmZXH0bEBidmRiY3HsZ4lncWOjdHnvci=> M2fSOlI{PjV5OEKy
HM7  MnXlRZBweHSxc3nzJGF{e2G7 MUWyNO69VcLi NYLIPXk1OWh? MVLicI9kc3NiYYDpZ5Vt[XKnbjDBJIFk\XSjdHWtbY5lfWOnZDDjZZNx[XOnLUOgZYN1cX[jdHnvckBidmRiUFHSVEBkdGWjdnHn[S=> NYnGb3R4OjN3OEO0NVI>
Hep-2  M1fPWmFxd3C2b4Ppd{BCe3OjeR?= M2rBXFIx|ryPwrC= NELtfoozPGh? MYfEUXNQ NEWxe3JidGyndnnheIV{KHSqZTDk[YNz\WG|ZTDv[kBk\WyuII\pZYJqdGm2eTDpcoR2[2WmIHL5JJNqdGmkaX7pci=> NH7LTlUzOzV6MECzNi=>
HSCs NHPOSVdCeG:ydH;zbZMhSXO|YYm= NHvaO|M2OM7:TR?= NF21emczPGh? M3:0fGROW09? M321[YlvcGmkaYTzJI5qdG:2aX7pZk1qdmS3Y3XkJGRPSSCmYX3h[4UhcW6maXPheIVlKGK7IGDBVnAh[2ynYY\h[4U> MlvFNlM1QTl6N{S=
HL-60  NVXHPXJxS3m2b4TvfIlkcXS7IFHzd4F6 NWGzNJFsOjEQvF5CpC=> M{XlZVI1cA>? MYHy[YR2[2W|IITo[UBkgXSxdH;4bYMh\W[oZXP0JI9nKEW{eUW= MUeyN|Q6PDR6MB?=
HA NELud3ZCeG:ydH;zbZMhSXO|YYm= MnP1OVDPxE1? NWrofYtjOjSq M4jKVZN2eHC{ZYPz[ZMhfGinIHPs[YF3[WenIH;mJHBCWlBiYX7kJINie3Cjc3WtN{whNTduIHHu[EAuQSCrbnT1Z4VlKGK7IHLvdpRmgm:vaXKvV2FJSQ>? NWPVZZlVOjN2N{W5OVY>
C666-1 MknuRZBweHSxc3nzJGF{e2G7 NGrySlU2OM7:TR?= MoLQNlRp Mlryd5VxeHKnc4Pld{B1cGViY3zlZZZi\2Vib3[gVGFTWCCjbnSgZ4F{eGG|ZT2zMEAuPyxiYX7kJE06KGmwZIXj[YQh[nliYn;yeIV7d22rYj;TRWhC MnXmNlM1PzV7NU[=
Hepa1-6 MnvxRZBweHSxc3nzJGF{e2G7 M1XFVFUx|ryP MUGybC=> M{P1Z4lvcGmkaYTzJIN2emO3bXnuJIFv\CC{ZYP2[ZJifHKxbD3pcoR2[2WmIHHwc5B1d3Orcx?= MWWyN|Q1Pjd3Mx?=
PLC/PRF/5c NEKyWIRCeG:ydH;zbZMhSXO|YYm= Ml[xOVDPxE1? MWKxbC=> MkiwdJJmfmWwdIOgZZBweHSxc3nzJJRzcWepZYLl[EBjgSCFSV6= MWKyN|Q{QDh{NB?=
HCT116 MoLTRZBweHSxc3nzJGF{e2G7 MkfmNVAx|ryP MV2xMlVp MUnpcohq[mm2czDPd{1qdmS3Y3XkJINmdGxiZHXheIg> M4nNb|I{PzR2M{Wz
HCEC NVTMSYpqTnWwY4Tpc44hSXO|YYm= MkDrOVDPxE1? NYfVNIwzPzKq NF;VXo5FVVOR M{jwOJJme3SxcnXzJI9nKHSqZTDuc5Ju[WxiSFPFR{BxcGWwb4T5dIU> Mn7DNlM4PDJyMUG=
Primary rat cerebral cortical neurons NVrqeYdzSXCxcITvd4l{KEG|c3H5 NWPxfpdjOTByzszN M2D2elFp NYq2SWI4eHKndnXueJMhS2RvaX7keYNm\CCjcH;weI9{cXNiYX7kJINmdGxiZHXheIg> NYHEdHlOOjN5NEGzNVc>
MDA-MB-231  MUnBdI9xfG:|aYOgRZN{[Xl? NVfLdFJoOjYQvF2= MYWyOIg> NHzxWmFi[nKxZ3H0[ZMh[3m2b4TvfIlkcXS7IHHu[EBkdGWjdnHn[UBw\iClYYPwZZNmNTNiYX7kJHBCWlBiaX7keYNm\CCkeTDS[|M> MVWyOVM{PzV2NB?=
NLRP3-Tet-on-MC/9  MV3BdI9xfG:|aYOgRZN{[Xl? MXyxNE01OM7:TR?= NXK2Zpo2OTKq Mle3ZZR1\W63YYTld{B1cGViY3XscEBl\WG2aDDjZZV{\WRiYomgR2FRWy2jc4PvZ4lifGWmIF7MVnA{KG23dHHueJMhcW5idHjlJHRmfC2xbjDzfZN1\W1? NFz0S2EzOzdyM{O4PS=>
KNS42  NXTtZZJHSXCxcITvd4l{KEG|c3H5 NY\F[nhJPTEQvF2= NFztfIsycA>? NWf6ZW8zemWmdXPld{Bk\WyuIHTlZZRpKGGwZDDjc41xdGW2ZXz5JIFjd2yrc3jl[EBk[XOyYYPlJFMwPyCjY4Tpeol1gSCrbjDy[ZNxd26|ZTD0c{BCSlRvMk[zM|JFTy:vZYTmc5JucW5iY3;tZolv[XSrb36= NHv4eZgzOzZ7MUG0OS=>
MCF-7  M1rYWmFxd3C2b4Ppd{BCe3OjeR?= MVOyNO69VcLi M{L6VVczcA>? NHqwOoJqdmirYnn0d{BmeXWxbD2gZY5lKDRvT1jUMY1m\GmjdHXkJIFxd3C2b4Ppdy=> NXXLRWlmOjN4N{W2OFM>
hCMEC/D3  MWjBdI9xfG:|aYOgRZN{[Xl? NFrlfFEzPc7:TR?= M1m3eVczcA>? M12xZZJm\HWlZYOgUJR5SSCrbnT1Z4VlKGGyb4D0c5Nqew>? NUXXWm51OjN4NkWxPVg>
Jurkat M1PZU2Fxd3C2b4Ppd{BCe3OjeR?= MUGxNk42NTVyzszN MXKxbC=> NGG2NXJld3OnIHTldIVv\GWwdHz5JJN2eHC{ZYPz[ZMhW1CKLXnu[JVk\WRiUHHyMVQh[2ynYY\h[4UtKFCDUmCgZ4xm[X[jZ3WsJGRPSSCocnHncYVvfGG2aX;uMEBidmRibH;zd{Bw\iC4aXHibYxqfHl? MYSyN|Q1Ojl5Nh?=
CNE-1 MmTWRZBweHSxc3nzJGF{e2G7 M4fsT|Ix|ryPwrC= MXSyOIg> Mn\ibY5pcWKrdIOgVmFFODBzLXnu[JVk\WRiY3XscEBl\WG2aB?= Mk\rNlM1OjZ6NUC=
HONE-1 NYLw[HpDSXCxcITvd4l{KEG|c3H5 MXuyNO69VcLi MmTONlRp MULpcohq[mm2czDSRWQxODFvaX7keYNm\CClZXzsJIRm[XSq NV7wWno4OjN2Mk[4OVA>
astrocytes cell NU\HNnFqSXCxcITvd4l{KEG|c3H5 M4XXOVQx|ryP MUS2bC=> NHe2S|Zz\WS3Y3XzJIViemy7IHHwc5B1d3OrczDpcoR2[2WmIHL5JJN1[XW{b4Pwc5JqdmV? NUDQSZltOjN2MUG3O|g>
U-937 M{O5TGFxd3C2b4Ppd{BCe3OjeR?= NVi0ZlhDOTEQvF2= M1nsW|MxdWmw NEfXbYdxemW4ZX70d{BVVkZvaX7keYNm\CCwZXPyc5B1d3Orcx?= NV62RVdmOjN2MUC3OFg>
MDA-MB-231 MkjsRZBweHSxc3nzJGF{e2G7 MUCxNFDPxE1? M2L2ZlFp NV2xWJJIcW6qaXLpeJMhe2Wwc3n0bZpifGmxbjD0c{BVWkGLTDD1dI9vKE2WRFig[I94di2{ZXf1cIF1cW:w MkLnNlM1ODh2Mkm=
HeLa  MVvBdI9xfG:|aYOgRZN{[Xl? MXGxNFDPxE1? Mne2Nog> MX7icI9kc3NiSmLTMVE2KEmwZIXj[ZMhSXCxcITveIlkKEOnbHygSIVifGh? MV2yN|M1PDB2NR?=
Ec109 NWXke4dMSXCxcITvd4l{KEG|c3H5 MnHhNVDPxE1? MoTWOog> NUnHOGV[[myxY3vzJIFxd3C2b4TpZ{Bkd22kaX7heIlwdiCxZjDUZZQuW22jY163JIFv\CC{YXTpZZRqd25? NVq3U25MOjN|M{i1Olg>
H460  MVPBdI9xfG:|aYOgRZN{[Xl? NXroUlc2OTEQvF2= NEnr[Fk3cA>? MVPicI9kc3NiYYDvdJRwfGmlIHPvcYJqdmG2aX;uJI9nKFSjdD3TcYFkVjdiYX7kJJJi\GmjdHnvci=> M33mV|I{OzN6NU[4
HeLa  NHLqUoJCeG:ydH;zbZMhSXO|YYm= MmXoOVDPxE1? MkL0NU42cA>? NWK2dmc5[WK{b3fheIV{yqCFaHzhcZllcWFvaX7keYNm\CCjcH;weI9{cXN? Mo\QNlM{ODN6MES=
SK-HEP1 NXnzXYxFSXCxcITvd4l{KEG|c3H5 M3XLUVExOM7:TR?= NUS3RXRsOWh? M1XHUIlvcGmkaYTzJGNzXDFiYXP0bZZifGWmIHPhd5Bie2VvMzygMVctKC16LDCtPUwh[W6mIIDvcJkpSUSSLYLpZo9{\SlicH;sfY1memG|ZR?= M1fqTFI{OzB{NkWw
QGY7701 MVvBdI9xfG:|aYOgRZN{[Xl? NIXRXWYzPc7:TR?= MVexMlVp MXTpcohq[mm2czDhZ4N2dXWuYYTpc44hd2Zic4XiMWcyKHCqYYPlJIlv\HWlZXSgZpkhTE:[IDugdZVmemOndHnu M3e5TFI{OjRyME[x
HepG2 NInuZWlCeG:ydH;zbZMhSXO|YYm= MoXGNlDPxE1? M2rOV|MxdWmw NYflZmc3cW6qaXLpeJMhfGinIHXubIFv[2WmIHPlcIwh\GWjdHigZpkh[2:vYnnu[YQhfHKnYYTt[Y51KG:oIHHwbYdmdmmwIHHu[EBVWkGLTB?= NVyzbpBWOjN{MkSyN|k>
U87  MWjBdI9xfG:|aYOgRZN{[Xl? MYiyOe69VQ>? M3HE[VJp NEDZUHJl\WO{ZXHz[ZMhcXOxbHnxeYlzcXSrZ3XubY4hMEmVTDmtbY5lfWOnZDDhdI9xfG:2aXOgZ4VtdCCmZXH0bEwh[nW2IH7veEBv\WO{b4TpZ{Bk\WyuIHTlZZRp M3PybFI{OjJ7NkK2
HSC-2 M3jNTmFxd3C2b4Ppd{BCe3OjeR?= MXOyOU82OM7:TR?= Ml7nNYg> MUTpcohq[mm2czDTUk0{QC2rbnT1Z4VlKGO7dH;0c5hq[2m2eR?= MWOyN|E2PTJ2OB?=
HSC-4 NFX1W4dCeG:ydH;zbZMhSXO|YYm= M3jyZVI2NzVyzszN MVqxbC=> NW\RN4xQcW6qaXLpeJMhW05vM{itbY5lfWOnZDDjfZRwfG:6aXPpeJk> M{XTRlI{OTV3MkS4