Bacterial

抑制剂选择性比较

Bacterial产品

所有产品(223) Bacterial抑制剂(48)

目录号	产品描述	文献引用	实验数据
S3021	Rimonabant (SR141716) Rimonabant (SR141716)是一个大脑中心大麻素受体（CB1）特异性口服拮抗剂。在hCB1转染HEK293细胞中IC50浓度为13.6 nM，EC50浓度为17.3 nM。Rimonabant也是一种acyl CoA:cholesterol acyltransferases(ACAT) 1和2的双重抑制剂并且可抑制分支杆菌的MmpL3。	Nat Commun, 2020, 11(1):5962 Sci Rep, 2020, 10(1):15556 Microbiol Immunol, 2020, 10.1111/1348-0421.12777
S1162	Pretomanid (PA-824) PA-824是一种抗肺结核药，作用于tuberculosis，MIC为<1 μg/mL。Phase 2。
E0365^New	Fucoidan Fucoidan是从海洋褐藻中提取的阴离子硫酸化多糖，具有广泛的生物活性，包括抗炎、抗癌、抗病毒、抗氧化、抗凝、抗血栓、抗血管生成和抗幽门螺杆菌等。
E0052^New	Merafloxacin Merafloxacin (CI-934) 是一种氟喹诺酮类抗菌剂，可抑制 SARS-CoV-2 和其他 β 冠状病毒的 -1 移码效率。
E0010^New	Hypocrellin A Hypocrellin A (HA) 是一种从 Shiraia bambusicola 中分离的苝醌，显示出抗病毒、抗菌和抗癌的活性。Hypocrellin A 还是 PKC 的选择性和有效抑制剂。
S1677	Chloramphenicol Chloramphenicol (Chloromycetin)是通过抑制蛋白质的合成的抑菌剂。	EMBO Rep, 2021, e53081 Cell Rep, 2021, 34(3):108631 Oncotarget, 2018, 9(40):26086-26095
S2457	Clindamycin HCl Clindamycin HCl 是Clindamycin的水合盐酸盐，是一种半合成的抗生素。	Proc Natl Acad Sci U S A, 2016, 113(50):14408-14413
S2908	Hygromycin B Hygromycin B (Hygrovetine)是选择性抗生素，有效作用于大多数细菌，真菌，和更高等的真核生物，通过干扰易位，抑制蛋白合成，造成70S核糖体的错译。	Autophagy, 2021, 1-17 PLoS Pathog, 2021, 17(4):e1009530 Cell Res, 2020,
S1762	Pyrazinamide Pyrazinamide (Pyrazinoic Acid Amide) 是一种治疗肺结核的药物。
S1791	Bacitracin Zinc Bacitracin是一种抗生素，能够干扰C55-isoprenyl pyrophosphate的去磷酸化，C55-isoprenyl pyrophosphate是一种膜载体分子，参与转运构成肽聚糖细菌细胞壁内膜外部成分。Bacitracin抑制甲硫啡肽中Tyr的裂解，IC50为10 μM。
S1618	Sulfameter Sulfameter 是一种长效的磺胺类抗菌药。
S1685	Sulfanilamide Sulfanilamide是细菌酶中二氢喋呤合成的适度竞争性抑制剂，IC50为320 μM。
S1881	Protionamide Protionamide (Prothionamide, 1321-TH) 用于治疗肺结核的一种药。	Mol Imaging Biol, 2021, 10.1007/s11307-021-01689-8
S3295	Taxifolin 7-rhamnoside Taxifolin 7-rhamnoside (TR, Taxifolin 7-O-rhamnoside, Taxifolin 7-O-α-L-rhamnoside) 是一种从 Hypericum japonicum 中分离出的类黄酮，其具有对抗耐甲氧西林金黄色葡萄球菌 (MRSA).的临床分离株的抗菌活性。
S5199	Oxytetracycline hydrochloride Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride 是一种抗生素，会干扰细菌产生必需蛋白质的能力。	Front Microbiol, 2016, 7:1765
S4490	Tetracycline Tetracycline (TC) 是一种广谱的抗生素，对多种微生物具有活性，包括革兰氏阳性和革兰氏阴性细菌、衣原体、支原体、立克次氏体和原生动物寄生虫。
S2830	Clindamycin Clindamycin通过作用于50S ribosomal subunits（50S核糖体亚基）而抑制蛋白合成。
S9226	Steviolbioside Steviolbioside (CCRIS-6025), a natural sweetener, exhibits moderate antituberculosis activity against M. tuberculosis strain H37RV in vitro.
S5186	Cefpiramide Cefpiramide (Cefpiramide acid, Cefpiramido, Cefpiramidum, WY-44635, SM-1652) 是一种具有广谱抗菌活性的假单胞菌活性头孢菌素。
S5008	Ciprofloxacin hydrochloride Ciprofloxacin (CPX, Cetraxal, Ciloxan, Cipro, Bay-09867) hydrochloride 是一种氟喹诺酮盐酸盐，一种具有广谱抗菌活性的β-二酮类抗生素。Ciprofloxacin 是细菌 DNA gyrase (一种 Type II topoisomerases 亚型) 的抑制剂。
S3496	Lefamulin acetate (Xenleta) Lefamulin acetate (Xenleta, BC-3781 acetate) 是一种截短侧耳素抗生素，用于 community-acquired bacterial pneumonia (CABP) 的治疗。Lefamulin acetate 通过与 50S bacterial ribosome 的肽基转移酶中心结合来抑制蛋白质合成，从而阻止了转移RNA与肽转移的结合。
S5495	Ceftiofur sodium Ceftiofur sodium 是一种半合成的、β-内酰胺酶稳定的广谱头孢菌素，具有抗菌活性。
S3499	Monocaprylin Monocaprylin (2,3-dihydroxypropyl octanoate, Monoctanoin, 1-Octanoyl-rac-glycerol, MC) 对金黄色葡萄球菌和大肠杆菌具有优异的抗菌活性。
S7550	Erythromycin Cyclocarbonate Erythromycin Cyclocarbonate，红霉素的衍生物，通过结合于50S核糖体抑制细菌蛋白质合成。
S4861	Oxindole Oxindole (2-indolone, 2-Oxindole, Indolin-2-one)是芳香族杂环有机化合物，当剂量过量时，可引起镇静、肌无力、低血压和昏迷。
S4647	Cefmenoxime hydrochloride Cefmenoxime (SCE-1365), 肠杆菌科的有效抑制剂，是一种头孢菌素抗生素，通常用于静脉注射或肌内注射。
S6867	Glyceryl monocaprate (Monocaprin) Monocaprin (Glyceryl caprate)是癸酸的1一甘油酯，对包膜病毒、某些细菌和白色念珠菌具有抗菌的活性。
S4602	Acetohydroxamic acid Acetohydroxamic acid (N-Hydroxyacetamide, Methylhydroxamic acid, Acetic acid\|oxime, Lithostat) 是尿素酶抑制剂。在尿液中，它可作为细菌酶尿素酶的拮抗剂。
S6549	PBTZ169 PBTZ169 (macozinone)是DprE1的不可逆性抑制剂，是一种抗生素。	Cell Death Dis, 2019, 10(4):319
S6584	Amdinocillin Amdinocillin (Mecillinam, Coactin, FL 1060) 是一种β-内酰胺抗生素，具有广泛的抗菌活性。Amdinocillin 单独可对许多革兰氏阴性菌都有活性。
S0147	KKL-10 KKL-10 是一种 ribosome rescue 的抑制剂，对细菌具有优异的广谱抗菌活性。
S4307	Auranofin Auranofin (Ridaura, SKF-39162) 是一种 thioredoxin reductase (TrxR) 的抑制剂，在无细胞分析中对纯化的幽门螺杆菌TrxR的IC50值为88 nM。Auranofin 具有抗癌活性，在1.2 μM浓度下可以完全抑制细菌的生长。Auranofin 是一种FDA批准的含金化合物，用于治疗类风湿关节炎。	Oncotarget, 2018,
S4983	Sorbic acid Sorbic acid (2,4-Hexadienoic acid) is a naturally occurring compound that originated from the unripe berries of the Rowan Tree. It inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division).
S4198	Aminothiazole Aminothiazole作为甲状腺抑制剂，具有抗菌活性。	J Electroanal Chem (Lausanne), 2020, 878:114733
S3710	Fosfomycin calcium Fosfomycin (phosphomycin, phosphonomycin) 是一种杀菌剂，可通过使UDP-N-acetylglucosamine-3-enolpyruvyltransferase失活而一直细菌细胞壁形成。Fosfomycin可通过甘油磷酸盐转运蛋白进入细胞壁。
S5166	Benzoyleneurea Benzoyleneurea (2,4-Dihydroxyquinazoline, Quinazolinedione, Quinazoline-2,4-diol) scaffold is used in the synthesis of novel protein geranylgeranyltransferase-I inhibitors.
S6090	JFD01307SC JFD01307SC ([(1,1-dioxidotetrahydrothien-3-yl)amino]acetic acid)对结核分枝杆菌 M.tuberculosis 具有活性，最低抑菌浓度 (MIC) 范围为 8-16 µg/ml。JFD01307SC 可能靶向参与谷氨酰胺 (glutamine) 生物合成的酶。
S4105	Closantel Sodium Closantel Sodium是革兰氏阳性的抗菌活性抑制剂，抑制KinA/Spo0F系统，IC50为3.8 μM。
S4106	Closantel Closantel (R-31520) 是革兰氏阳性的抗菌活性抑制剂，抑制KinA/Spo0F系统，IC50为3.8 μM。
S6464	Ftaxilide Ftaxilide是一种新型的抗痨药。
S0195	Walrycin B Walrycin B 是一种抗菌化合物，是一种靶向WalR反应调节剂的 WalR 的有效抑制剂。
S4780	7-Methoxy-4-methylcoumarin 7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label.
S5201	Acetylisovaleryltylosin Tartrate Acetylisovaleryltylosin tartrate (AK105039)是一种具有抗菌作用的大环内酯物，对革兰氏阳性细菌具有抑制活性。
S4425	Rifamycin S Rifamycin S 是一种quinone和抗 Gram-positive bacteria(包括MRSA) 的抗生素，是一种用于治疗肺结核和麻风病的临床药物。Rifamycin S 可产生 reactive oxygen species (ROS)，并抑制微粒体脂质过氧化 microsomal lipid peroxidation。
S4436	Pleuromutilin Pleuromutilin (Drosophilin B, Mutilin 14-glycolate) 是新型抗生素的先导化合物，它通过结合细菌的50S核糖体亚基来抑制细菌蛋白质的合成。
S7739	Telacebec (Q203) Telacebec (Q203, IAP6) 是一种新型抗结核药物，通过抑制分枝杆菌细胞色素 bc1 复合物来靶向结核分枝杆菌（Mycobacterium tuberculosis）细胞能量的产生。Telacebec 对结核分枝杆菌 H37Rv 具有活性，在培养基中的 MIC50 为 2.7 nM。
S4404	Pasiniazid Pasiniazid，由isoniazid和4-aminosalicylic acid组成，用于治疗肺结核患者。
S4854	Bedaquiline fumarate Bedaquiline fumarate (TMC-207), an oral diarylquinoline, is a bactericidal antimycobacterial drug. It is a proton-translocating ATP synthetase inhibitor.	Adv Healthc Mater, 2022, e2102117
S1373	Daptomycin (LY146032) Daptomycin (LY146032)是一种新型抗生素，在体外对革兰氏阳性菌具有快速的杀菌活性。	J Phys Chem B, 2021, 125(22):5775-5785 Sci Adv, 2020, 6(34):eaba8968 Front Microbiol, 2020, 21;11:646	Same experiment as in Figure 2 with fluorescent daptomycin shown as confocal images. A 7/3 DOPC/DOPG GUV (including 1% Rh-PE) was introduced at time zero into a solution containing 1 uM daptomycin with 0.5 uM BODIPY-daptomycin and 1 mM Ca2+. To show colocalization of lipid and peptide in aggregates, confocal images were taken: red for RH-PE and green for BODIPY-daptomycin. As the protrusion length decreased, aggregates appeared on the GUV surface containing both lipid and peptide. The scale bar is 10 um.
S1097	BTZ043 Racemate BTZ043 Racemate是一种decaprenylphosphoryl-β-D-ribose 2’-epimerase的抑制剂，是一个可以杀死结核杆菌的新的抗分支杆菌的药物。	Drug Deliv Transl Res, 2021, 11(4):1766-1778 J Med Chem, 2020, 28;63(10):5367-5386 Biochem Pharmacol, 2019, 162:41-54
S1403	Tigecycline (GAR-936) Tigecycline (GAR-936) 是一种甘氨酰环素类抗生素，具有抑菌作用，是一种蛋白质合成的抑制剂，通过与细菌的 30S核糖体亚基结合，从而在原核翻译过程中阻止氨酰tRNA进入核糖体的A位点。Tigecycline 可通过下调PI3K-AKT-mTOR途径诱导自噬。	iScience, 2021, 24(11):103350 Biomolecules, 2020, 10(10)E1395 Aging (Albany NY), 2020, 12(12):11364-11385	CHX blocked Pim-1 AUG isoform translocation from the cytosol to mitochondria and led to reduced pBADS112. Cox-2 was examined to assess the effect of tigecycline on mitochondrial translation. Cy-Cox-2: cytoplasmic Cox-2; Mt-Cox-2: mitochondrial Cox-2.
S1741	Rifabutin (LM427) Rifabutin (LM427, Ansamycin) 是一种半合成的Ansamycin 抗生素，具有有效的抗分枝杆菌特性。	Antibiotics (Basel), 2020, 9(2) Antimicrob Agents Chemother, 2020, AAC.00363-20
S1370	Biapenem Biapenem (L-627, LJC10627) 是一种碳青霉烯类抗生素，抑制了革兰氏阳性菌以及革兰氏阴性菌的活性。
S1399	Teicoplanin Teicoplanin (Teichomycin) 是一种预防用的抗生素。	ACS Appl Mater Interfaces, 2020, 12(14):16150-16158 Clin Exp Dent Res, 2016, 2(1):35-43
S1505	Aztreonam Aztreonam (SQ 26776) 是一种合成的单环β-内酰胺类抗生素。	PLoS Pathog, 2016, 12(10):e1005932 Expert Opinion on Orphan Drugs, 2013, 1(7):549-556
S1768	Cefditoren Pivoxil Cefditoren Pivoxil (ME-1207) 是一种广谱的抗生素，用于治疗格兰仕阳性菌和阴性菌感染。
S1839	Chloroxine Chloroxine是一种人工合成的抗菌化合物，加入洗发液中，有效治疗头皮屑和脂溢性皮炎。	Hum Mol Genet, 2020, ddaa244 Front Microbiol, 2020, 10:2936
S1605	Cefdinir Cefdinir (FK 482, PD 134393, CI-983) 是一种杀菌抗生素。
S1502	Cephalexin Cephalexin (Cefalexin)是可以治疗许多细菌感染的抗生素。	Clin Cancer Res, 2018, 24(3):659-673 Theranostics, 2017, 7(7):2092-2107 Blood Cancer J, 2017, 10.1038/bcj.2017.61
S1835	Azithromycin (CP-62993) Azithromycin (CP-62993, XZ-450)是一种抑制蛋白合成的抗生素，用于细菌感染的治疗。	J Cell Biochem, 2022, 10.1002/jcb.30213 Hum Cell, 2022, 10.1007/s13577-022-00671-y Hum Cell, 2021, 34(6):1911-1918
S1773	Oxytetracycline (Terramycin) Oxytetracycline(Terramycin) 是第二个被发现的广谱四环素类抗生素。	Sci Rep, 2018, 8(1):7653 Front Microbiol, 2016, 7: 1765	Effect of FDA approved drugs on EBOV transfected donor and recipient immune cells. (A) Varying concentrations of Cambinol and Esomepraole (1 nM, 1 μM, 10 μM), Oxytetracycline (1 nM, 10 nM, 10 μM), and DMSO (0.00001, 0.0001, 0.001%) treatments were administered to VP40-transfected 293T cells, followed by incubation for 3 days. Supernatant was centrifuged to remove cellular material and subsequently incubated for 72 h at 4°C with 20 μL of 30% slurry of NT80/82 beads. The NT pellet was washed twice with PBS and resuspended in SDS Laemmli buffer, followed by Western blot analysis for levels of exosomal markers CD63 and Alix. Actin levels were also analyzed. Mid-log phase EVTR2C cells (containing VP40) were treated with either low (0.1 μM), medium (1 μM), or high (10 μM) concentrations of Oxytetracycline and incubated for 5 days along with untreated 293T cells. Cell-free supernatants were harvested, filtered, and used to treat CEM (B), Jurkat (C), and U937 (D) cells. Cells were incubated for 5 days and assayed with CellTiter-Glo for viability. Statistical significance was determined using two-tailed student’s t-test with all groups compared to the untreated 293T cell control groups. RLU, Relative Luminescent Units. ∗p < 0.05, ∗∗∗p < 0.001.
S2568	Neomycin sulfate Neomycin sulfate属于氨基糖苷类抗生素。	Mol Cell, 2020, 22 pii: S1097-2765(20)30231-8
S2420	Aloperine Aloperine是提取自苦参植物，如Sophora alopecuroides L的生物碱，具有抗炎，抗菌，抗病毒,和抗肿瘤的特性。	Cancer Cell Int, 2021, 21(1):662 Tissue Cell, 2021, 74:101706 J Cancer Res Clin Oncol, 2020, 10.1007/s00432-020-03157-2
S2565	Amoxicillin Sodium Amoxicillin Sodium (Clavulanate) 是一种中等谱，溶菌，β-内酰胺类抗生素。	ChemMedChem, 2022, e202200043 PLoS Comput Biol, 2020, 16(12):e1008489 Toxicol Appl Pharmacol, 2015, 285(1):51-60
S2544	Cefprozil hydrate Cefprozil hydrate 是第二代头孢菌素类抗生素。
S2563	Oxacillin sodium monohydrate Oxacillin sodium monohydrate (Methicillin)是一种抗菌剂，是一种窄谱，青霉素类的β-内酰胺类抗生素。
S3129	Trimethoprim Trimethoprim (BW 56-72, NIH 204, NSC-106568) 是一种抑制细菌的抗生素，主要用于预防和治疗尿路感染。
S1915	Sulfamethoxazole Sulfamethoxazole 是磺胺类抑制细菌的抗生素，IC50为2.7 μM。
S2575	Vancomycin HCl Vancomycin HCl 是Vancomycin的盐酸盐，是一种窄谱的糖肽类抗菌剂。	Elife, 2021, 10e64237 Gut Microbes, 2020, 12(1):1-20 Oncotarget, 2018, 9(40):26086-26095
S2543	Ceftiofur HCl Ceftiofur HCl (U-67279A)是Ceftiofur的盐酸盐，是一种广谱头孢菌素。
S1916	Sulfisoxazole Sulfisoxazole (NU-445) 是一种磺胺类抗菌药，具有一个恶唑取代基。
S3195	Azlocillin sodium salt Azlocillin sodium salt是一种酰基氨苄青霉素，具有广谱抗菌作用。
S4004	Ethambutol 2HCl Ethambutol 2HCl (CL40881)是一种抗分枝杆菌抑菌剂, 通过抑制阿拉伯糖基转移酶来干扰细胞壁形成。	Molecules, 2019, 25(1)
S4146	Bacitracin Bacitracin是由Bacillus subtilis var生物体产生的相关环状多肽组成的混合物，通过干扰细胞壁肽聚糖的合成，从而破坏革兰氏阳性和革兰氏阴性细菌。	Onco Targets Ther, 2020, 13:9543-9558 Anal Chem, 2017, 89(16):8501-8508 Chem Res Toxicol, 2017, 30(10):1804-1814
S3015	Amoxicillin Amoxicillin (Amoxycillin) 是一种温和β-内酰胺抗生素，用于治疗敏感菌引起的微生物细菌感染。	ChemMedChem, 2022, e202200043 PLoS Comput Biol, 2020, 16(12):e1008489 Toxicol Appl Pharmacol, 2015, 285(1):51-60
S1957	Sulfamethizole Sulfamethizole 是一种磺胺类抗菌剂。
S4093	Bismuth Subcitrate Potassium Bismuth Subcitrate是一种抗生素，用于治疗感染幽门螺旋杆菌的胃溃疡。	Cell Rep, 2022, 38(6):110359 J Clin Invest, 2020, 130(7):3901-3918
S3122	Amikacin hydrate Amikacin hydrate 是一种氨基糖甙类抗生素，用于治疗不同类型的细菌感染。	Molecules, 2019, 25(1)
S3133	Sulfamethazine Sulfamethazine是一种磺胺类抗菌药,是一种用来治疗支气管炎，前列腺炎以及尿道感染的抗生素。Sulfamethazine 通过抑制二氢叶酸合成酶活性来阻断二氢叶酸合成。此外， sulfamethazine 是一种对氨基苯甲酸(PABA)的结构类似物和竞争性拮抗剂，可以抑制正常的细菌利用PABA 来合成叶酸，而叶酸是一种重要的DNA合成代谢物。
S1855	Pefloxacin Mesylate Pefloxacin Mesylate是一种合成的化疗药物和抗菌剂，IC50为6.7 nM。	J Biol Chem, 2019, 294(49):18624-18638
S3179	Carbenicillin disodium Carbenicillin (BRL-2064) 是一种半合成的青霉素抗生素，可以干扰革兰氏阴性菌细胞壁的合成，具有低毒性。
S3193	Ticarcillin sodium Ticarcillin (AB 2288, BRL 2288) 是一种半合成的抗生素，对多种革兰氏阳性和阴性需氧以及厌氧菌具有广谱杀菌活性。
S5227	Erythromycin thiocyanate Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits and inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
S5352	Cefminox Sodium Cefminox Sodium (Meicelin, MT-141) is the sodium salt form of cefminox, a semi-synthetic, second-generation, beta-lactamase-stable cephalosporin with antibacterial activity.
S6235	Sodium dehydroacetate Sodium dehydroacetate是无水醋酸的钠盐形式。无水醋酸是一种杀菌剂，通常被用作食品防腐剂。
S3621	Pazufloxacin mesylate Pazufloxacin Mesylate (T-3762, Pazucross)，也被称作是Pazucross和T-3762，是一种喹诺酮类抗菌剂，用于多种感染的治疗。
S5560	Midecamycin Midecamycin (Espinomycin A, Medecamycin A1, Platenomycin B1, Rubimycin, Turimycin P3) is a naturally occuring macrolide antibiotic that acts by inhibiting bacterial protein synthesis.
S5406	Sultamicillin Tosylate Sultamicillin Tosylate is the tosylate salt of the double ester of sulbactam plus ampicillin. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would otherwise be resistant.
S5048	Fosfomycin Disodium Fosfomycin (Phosphonemycin)是一种具有杀菌活性的，低分子量、广谱抗生素，通过抑制细胞壁合成的早期阶段，对一些细菌具有潜在活性，如多药耐药的革兰氏阴性细菌。
S5051	Pipemidic acid Pipemidic acid (Acido pipemidico)是一类吡啶并嘧啶类抗生素，是piromidic acid的衍生物，对革兰氏阴性和某些革兰氏阳性细菌具有活性。	Hum Mol Genet, 2020, ddaa244
S4576	Sulfabenzamide Sulfabenzamide (Sultrin, N-Sulfanilylbenzamide) 是一种抗菌剂，它通过多种途径也可以发挥抗肿瘤效果。
S5353	Cefpiramide sodium Cefpiramide sodium (CPMS, SM-1652,wy-44635) is an anionic β-lactam antibiotic. It exhibits antibacterial activity against gram-positive and gram-negative bacteria, in particular, to Pseudomonas aeruginosa, which can result in achronic life-threatening infection in the lungs of cystic fibrosis patients.
S4848	Dalbavancin Dalbavancin (Zeven, BI 397, MDL 63397)是一种脂糖肽类抗生素，对革兰氏阳性菌，如多种葡萄状球菌，具有杀菌活性。
S5081	Ceforanide Ceforanide是一种新型头孢菌素，具有抗细菌活性，具有较长的消除半衰期。
S5951	Cefoxitin Cefoxitin是一种β-内酰胺、头孢菌素抗生素，具有杀菌活性。
S5356	Ceftiofur Ceftiofur is a semisynthetic, beta-lactamase-stable, broad-spectrum cephalosporin with antibacterial activity.	Vet J, 2018, 234:24-26
S5012	Octenidine Dihydrochloride Octenidine是一种阳离子型表面活性剂，对革兰氏阳性和阴性的细菌具有活性。
S3623	Ceftibuten dihydrate Ceftibuten Dihydrate is the dihydrate form of ceftibuten, a semisynthetic, beta-lactamase-stable, third-generation cephalosporin with antibacterial activity.
S4850	Flucloxacillin sodium Flucloxacillin sodium (Floxacillin sodium) is the sodium salt of flucloxacillin, a penicillin antibiotic used to treat bacterial infections.
S9224	Dehydroandrographolide Succinate Dehydroandrographolide succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, has antibacterial and antiviral effects.
S4846	Meropenem Trihydrate Meropenem is a broad-spectrum antibacterial agent of the carbapenem family with a broad spectrum of in vitro activity against Gram-positive and Gram-negative pathogens.
S5533	Tobramycin sulfate Tobramycin sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity.	Oncotarget, 2018, 9(40):26086-26095
S4594	Cephalothin sodium Cephalothin (Cefalotin, Cephalotin) sodium 是一种半合成的β-内酰胺类抗生素，第一代头孢菌素抗生素，具有杀菌活性。Cephalothin与位于细菌细胞壁内膜的青霉素结合蛋白（PBP）结合并使之失活。
S5941	Besifloxacin Besifloxacin是第四代氟喹诺酮类眼部抗生素，用于治疗细菌性结膜炎。
S4880	Cefathiamidine Cefathiamidine is the first generation of cephalosporin antibacterial used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis.
S5268	Solithromycin Solithromycin (CEM-101, OP-1068), belonging to the well-known class of macrolide antibiotics that also includes azithromycin, is a potent bacterial protein synthesis inhibitor.
S1617	Sulfapyridine Sulfapyridine 是一种磺胺类抗菌药。
S5332	Cefquinome sulfate Cefquinome sulphate is a veterinary, parenteral, and fourth-generation cephalosporin. Its antimicrobial potency and extensive antibacterial spectrum result from the introduction of a methoxyimino-aminothiazolyl moiety into the acyl side chain.
S5278	Tedizolid (TR-700) Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.
S4029	Colistin Sulfate Colistin (Polymixin E)是一种环状阳离子十肽，链接到脂肪酸侧链，属于一组结构类似的细菌抗微生物肽。	Front Pharmacol, 2021, 12:744494 Biogerontology, 2016, 17(5-6):907-920
S2052	Oxytetracycline Dihydrate Oxytetracycline Dihydrate 是一种处方抗生素，干扰细菌产生必需蛋白质的能力。	Front Microbiol, 2016, 7:1765
S5532	Erythromycin estolate Erythromycin (Lubomycine B), a naturally occurring macrolide, is derived from Streptomyces erythrus. It inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
S5535	Moxifloxacin Moxifloxacin is an antibiotic used to treat a number of bacterial infections, active against Mycobacterium tuberculosis in vitro.	Transl Vis Sci Technol, 2018, 7(2):11 J Pharmacol Toxicol Methods, 2017, 90:39-47 Circ Arrhythm Electrophysiol, 2016, 9(4):e003655
S5625	Ammonium lactate Ammonium lactate (Lac-hydrin) is the ammonium salt of lactic acid with mild anti-bacterial properties.
S4869	Sulfamethoxazole sodium Sulfamethoxazole sodium是一种用于治疗细菌感染的抗生素。
S5054	Rifamycin sodium salt Rifamycin sodium is an antibacterial drug used for treatment of mycobacterium infections.
S5491	Lomefloxacin Lomefloxacin is a fluoroquinolone antibiotic used to treat bacterial infections.
S5331	Ceftezole sodium Ceftezole Sodium (Celoslin sodium, Falomesin sodium) is the sodium salt form of ceftezole, a semi-synthetic first-generation cephalosporin with antibacterial activity.
S4595	Cefazolin Sodium Cefazolin Sodium (cefazoline, cephazolin, Ancef)是一种半合成的头孢菌素类似物，具有广谱抗菌作用，抑制细菌细胞壁的合成。它能达到较高的血清水平，通过尿液排泄出去。
S5936	Cefazolin Cefazolin是一种半合成的头孢菌素，具有广谱的抗菌作用，抑制细菌细胞壁的合成。它可达到高血清水平，通过尿液快速排泄。
S4596	Cefixime Cefixime (Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635) 是一种对于治疗许多细菌感染疾病有用的抗生素。
S4148	Ampicillin Trihydrate Ampicillin Trihydrate (NCI-C56086)是β-内酰胺类抗生素，通过使细菌细胞膜内表面上的转肽酶失活而抑制细菌细胞壁合成（肽聚糖的交联）。	Bone Joint Res, 2020, 16;9(4):152-161
S4875	Cephapirin Benzathine Cephapirin Benzathine是cephapirin的苄星青霉素盐形式。Cephapirin是半合成的、广谱的、第一代头孢菌素，具有抗菌活性。
S4885	Taurolidine Taurolidine (Taurolin, Tauroline, Tauroflex) 是一种合成的、广谱的抗生素，具有抗细菌、抗凝的和潜在的抗血管新生的活性。
S5492	Econazole Econazole is a broad spectrum antimycotic with some action against Gram positive bacteria.	Am J Cancer Res, 2020, 10(1):263-274 Biomol Ther (Seoul), 2020, 25
S4874	Cefazedone Cefazedone (Refosporen, Cefazedonum) 是一种半合成的一代头孢菌素，具有抗细菌活性。
S9466	Methenamine Hippurate Methenamine Hippurate是methenamine的马草酸盐形式，是一种前药和惰性弱碱，在酸性尿液中会水解成甲醛。Methenamine Hippurate是Hiprex药物的成分，具有抗菌活性。
S9292	Dictamnine Dictamnine, a natural plant product, has been reported to have antimicrobial activity against bacteria and fungi.
S5296	Cephradine monohydrate Cefradine is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.
S5487	Cefoperazone sodium Cefoperazone Sodium is the sodium salt form of cefoperazone, which is a semi-synthetic, broad-spectrum, beta-lactamase resistant antibiotic with bactericidal activity.
S4822	Silver Sulfadiazine Silver sulfadiazine是一种杀菌剂，对很多革兰氏阴性和阳性的细菌以及酵母都十分有效。
S5736	Benzathine penicilline Benzathine penicilline (Benzathine penicillin G) is an antibiotic useful for the treatment of a number of bacterial infections.
S1884	Sparfloxacin Sparfloxacin (AT-4140, CI-978, PD 131501)是一种喹诺酮类抗生素，具有广谱有效的抗菌活性。
S2385	Hordenine Hordenine是一种苯乙胺生物碱具有抗菌特性。
S4634	Sodium sulfadiazine Sodium Sulfadiazine (Sulfadiazin-natrium)是sulfadiazine的钠盐形式，一种具有中效抑菌作用的合成sulfanilamide衍生物。
S4959	Skatole Skatole (3-methylindole, Scatole)是一种具有轻度毒性的白色结晶有机化合物，天然存在于排泄物中，具有相当广泛的抑菌作用。
S5291	sulfaisodimidine Sulfaisodimidine (Sulfamethin) is a sulfonamide antibacterial.
S5235	Cefodizime Cefodizime (CEF, CDZ) 是一种氨基噻唑基头孢菌素，具有广泛的抗菌活性。
S5417	Spectinomycin dihydrochloride pentahydrate Spectinomycin dihydrochloride pentahydrate (Trobicin) 是一种广泛使用的抗生素，可通过阻止信使RNA的易位和核糖体上的转移RNA来抑制细菌蛋白质的合成。
S3644	Sulfamonomethoxine Sulfamonomethoxine is a long-acting sulfonamide antibacterial agent and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
S5298	Amoxicillin trihydrate Amoxicillin (Amoxil, Amoxipen, Moxaline) is a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity.	ChemMedChem, 2022, e202200043 PLoS Comput Biol, 2020, 16(12):e1008489
S5546	Sulfacetamide Sulfacetamide (Acetosulfamine) is a synthetic sulfanylacetamide derivative with bacteriostatic activity. It is an anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
S4179	Mezlocillin Sodium Mezlocillin Sodium是青霉素的beta-内酰胺类抗生素，通常用于治疗革兰氏阳性菌引起的感染。
S4060	Erythromycin Ethylsuccinate Erythromycin Ethylsuccinate, 是一种口服的大环内酯类抗菌素，由链霉菌产生, 可以可逆的结合细菌50S 核糖体并抑制蛋白合成。
S5515	Penicillin G Procaine Procaine benzylpenicillin (Procaine benzylpenicillin), also known as Procaine benzylpenicillin, is an antibiotic useful for the treatment of a number of bacterial infections.
S5289	Ceftezole Ceftezole (Celoslin, Falomesin) is a semi-synthetic first-generation cephalosporin with antibacterial activity.
S3655	Cefepime Dihydrochloride Monohydrate Cefepime is a cephalosporin antibacterial drug used to treat pneumonia, urinary tract, skin, and intra-abdominal infections.	ACS Chem Neurosci, 2021, 10.1021/acschemneuro.1c00608
S5637	Cefotiam Hexetil Hydrochloride Cefotiam Hexetil Hydrochloride is the hydrochloride salt of cefotiam hexetil. Cefotiam is a semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity.
S4541	Triclosan Triclosan (Irgasan, Cloxifenolum) 是在化妆品和香皂中被用作防腐剂的二苯醚衍生物。它具有抑菌作用。	FASEB J, 2019, 10.1096/fj.201802603RR Onco Targets Ther, 2018, 11:2945-2954
S5638	Cefozopran hydrochloride Cefozopran Hydrochloride is the hydrochloride salt form of cefozopran, a semi-synthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity.
S5644	Ceftriaxone Sodium Ceftriaxone Sodium is the sodium salt form of ceftriaxone, a beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity.
S4720	Cefotaxime Cefotaxime是第三代头孢菌素抗生素，对革兰氏阴性菌和阳性菌具有广谱活性。
S8871	Omadacycline tosylate Omadacycline tosylate 是氨甲环素类抗生素，对革兰氏阳性和阴性的需氧菌以及一些厌氧菌具有抗菌活性。
S5330	Amikacin Sulfate Salt Amikacin (BAY 41-6551) sulfate 是卡那霉素的半合成类似物，是一种氨基糖苷类抗生素，对大多数革兰氏阴性细菌，包括对庆大霉素和妥布霉素耐药的菌株，都具有非常强的活性。
S5420	Clindamycin alcoholate Clindamycin alcoholate is a crystallizable compound of Clindamycin with alcohol. Clindamycin is a semisynthetic lincosamide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
S4750	Sulfacetamide sodium salt hydrate Sulfacetamide是一种磺胺类抗生素，通过抑制dihydropteroate synthase(DHPS)阻滞二氢叶酸的合成。Sulfacetamide是细菌para-aminobenzoic acid (PABA)的竞争性抑制剂，PABA是细菌合成叶酸所必需的。
S9046	Berberine Berberine (Umbellatine), an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic.	Front Pharmacol, 2021, 12:632201 Brain Res Bull, 2021, 177:22-30 Biology (Basel), 2021, 10(3)250
S3636	Cefadroxil hydrate Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.
S3637	Cefpirome sulfate Cefpirome is a fourth-generation cephalosporin and is considered highly active against Gram-negative bacteria.
S3638	Cefamandole nafate Cefamandole Nafate is the sodium salt form of cefamandole formyl ester. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall, interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
S5440	Berberine Sulfate Berberine sulfate (Umbellatine), an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria, fungi, and protozoa.	Front Pharmacol, 2021, 12:632201 Biology (Basel), 2021, 10(3)250
S3350	Cholesteryl linoleate Cholesteryl linoleate 是一种人鼻液中极性较低的脂质，助力固有的抗菌活性。
S5784	Vancomycin Vancomycin是一种抗生素，用于治疗各种细菌感染。	Gut Microbes, 2020, 12(1):1-20 Oncotarget, 2018, 9(40):26086-26095
S3708	Sulfachloropyridazine Sulfachloropyridazine是一种抗生素，用于治疗多种细菌感染。
S4201	Florfenicol Florfenicol (SCH-25298) 是一种氟化的Thiamphenicol合成类似物，具有广谱的抑菌活性。
S4663	Fusidate Sodium Fusidate Sodium (Fucidin, SQ-16360) 是fusidic acid的钠盐形式，fusidic acid是一种来自于梭链孢菌的抑菌性抗生素，被用来作为局部药物治疗，治疗皮肤感染。
S3709	Furagin Furagin (NF-416, F-35, Akritoin, Furazidin, Furazidine)是一种2-substituted 5-nitrofuran，在化学结构上与已知的抗细菌化合物nitrofurantoin类似，具有抑菌活性。
S4203	Furaltadone HCl Furaltadone HCl是一种抗菌药，治疗球虫病具有明显的疗效。	Eur J Pharmacol, 2018, 828:119-125
S4986	Latamoxef sodium Latamoxef sodium (Moxalactam Disodium, FestamoxinLy, Shiomarin, Ly 127935, 6059 S) is an antibiotic and has anti-bacterial and anti-inflammation effects.
S6411	Nimorazole Nimorazole是一种水溶性的硝基咪唑化合物，具有抗细菌和潜在的放射增敏作用。
S3058	Danofloxacin Mesylate Danofloxacin (CP-76136-27) 是一种喹诺酮类抗菌剂，兽医用药，MIC90为0.28 μM。
S4271	Isepamicin Sulphate Isepamicin Sulphate (Isepamicine, Isepamycin, sch21420) 是一种氨基糖苷类antibiotic，以细菌30S核糖体亚基为靶点抑制细菌蛋白质的合成。
S3672	Cefonicid sodium Cefonicid sodium (Monocid) is a cephalosporin antibiotic. It interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism.
S4213	Dirithromycin Dirithromycin (LY-237216, ASE 136) 是大环内酯类糖肽抗生素，通过与细菌70S核糖体的50S亚基结合，从而抑制肽易位。
S4216	Valnemulin HCl Valnemulin是天然存在的二萜类抗生素pleuromutilin的半合成衍生物，它的作用是抑制肽基转移酶。
S5070	Mupirocin calcium Mupirocin Calcium (Pseudomonic acid A)是mupirocin的钙盐形式。Mupirocin是一种天然的巴豆酸衍生物，提取自荧光假单胞菌，抑制细菌蛋白质合成，被用作一种抗生素。
S6067	2,4-dichlorobenzyl alcohol 2,4-Dichlorobenzyl alcohol是一种温和的防腐剂，能够杀死口喉感染相关的细菌和病毒。
S9099	Orientin Orientin (Lutexin, Luteolin-8-glucoside), isolated from medicinal plants, has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects.
S2335	Oridonin (NSC-250682) Oridonin (Isodonol, Rubescenin, NSC-250682) 是从Rabdosia rubescens中分离的对映贝壳杉烷二萜,是一种具有抗肿瘤、抗细菌和抗感染效果的传统中药。Oridonin 抑制AKT1 和 AKT2的激酶活性，对应的IC50值分别为8.4 μM 和 8.9 μM。	Pharmacol Res, 2022, 178:106188 Int Immunopharmacol, 2022, 102:108387 J Exp Med, 2021, 218(9)e20202637	Histopathological analysis of H460 tumors following combination treatment with oridonin and radiation. Hematoxylin and eosin (H-E) staining and immunohistochemistry for cleaved caspase-3 and γ-H2AX were performed on tumors harvested at 14 days after IR. Representative images of H-E-stained tumors (upper images) and cleaved caspase-3- and γ-H2AX-positive cells (middle images, brown staining) and quantification of cleaved caspase-3 and γ-H2AX-positive staining with six mice in each group (lower plots, means ± SEM) are shown; * p < 0.05.
S5776	Proflavine Proflavine (3,6-Diaminoacridine)是一种消毒抑菌剂，可抑制许多革兰氏阳性菌。它常被用作伤口敷料中的局部杀菌剂。
S6444	Triclocarban Triclocarban是一种常用于个人护理用品中的抗细菌试剂。
S3650	Penicillin V potassium salt Phenoxymethylpenicillin, also known as penicillin V, is an antibiotic useful for the treatment of a number of bacterial infections. It acts by inhibiting the biosynthesis of cell-wall peptidoglycan.
S9328	5,6,7-Trimethoxyflavone 5,6,7-Trimethoxyflavone (Baicalein Trimethyl Ether), methylations of the hydroxyl groups of oroxylin A or baicalein, has various pharmacological activities including antiviral, anticancer and antibacterial.
S5036	Nisin Nisin (Ambicin N) 是一种核糖体合成的肽段，具有广谱的抑菌活性，抑制多种细菌包括食品腐败菌与致病菌。
S3121	Ornidazole Ornidazole (Ro7-0207, NSC 95075)是5-硝基咪唑衍生物，具有抗原虫和抗厌氧菌的抗菌性能。
S5924	Olanexidine Hydrochloride semihydrate Olanexidine (OPB-2045, OPB-2045G)是一种具有杀菌活性的单双胍化合物。
S5410	Chloramphenicol sodium succinate Chloramphenicol Sodium Succinate is the sodium succinate salt form of chloramphenicol, a nitrobenzene derivate and broad-spectrum antibiotic with antibacterial activity.	Oncotarget, 2018, 9(40):26086-26095
S4517	Cefotaxime sodium Cefotaxime sodium salt是第三代头孢菌素抗生素，是一种广谱的、具有抵抗大多数Gram-positive和Gram-negative细菌的抗菌剂。
S9122	Tectorigenin
S4518	Chloroxylenol Chloroxylenol是一种广谱的抗菌类化合物，用来抵抗细菌、藻类、真菌和病毒。
S5209	Enoxacin Sesquihydrate Enoxacin sesquihydrate (Enoxacin hydrate)是一种广谱的6-fluoronaphthyridinone抗菌剂。
S9377	Eugenyl acetate Eugenyl acetate, an aromatic component of clove essential oil, exhibits various pharmacological activities, including antibacterial and anti-virulence activities against drug-resistant A. baumannii clinical isolates.
S3132	Sulfamerazine Sulfamerazine (RP 2632) 是磺胺类抗菌药。
S5208	Ciprofloxacin hydrochloride hydrate Ciprofloxacin Hydrochloride (Ciloxan, Ceprimax, Oftacilox) 是ciprofloxacin的盐酸盐形式，ciprofloxacin是一种抗生素，用于治疗一些细菌感染疾病。
S3065	Amikacin disulfate Amikacin sulfate (BB-K8)是一种半合成，水溶性的卡那霉素氨基糖苷类衍生物，可以结合到细菌30S 核糖体亚基上引起mRNA读取错误从而导致细菌不能合成自身生长所必需的蛋白。
S4523	Dihydrostreptomycin sulfate Dihydrostreptomycin sulfate是氨基糖苷类抗生素，用来在牛、猪和羊中治疗细菌性疾病。Dihydrostreptomycin是链霉素的衍生物。
S5473	Pivmecillinam hydrochloride Pivmecillinam is a β-lactam antibiotic and a prodrug of mecillinam. It has selective activity against Gram-negative bacteria and is used primarily in the treatment of lower urinary tract infections.
S5202	Quinocetone Quinocetone是一种新型的兽用化合物，具有杀菌作用和潜在的抗肿瘤活性。
S4528	Furazolidone Furazolidone是一种合成的硝基呋喃衍生物。对Gram-positive和Gram-negative的细菌具有灭菌或抑菌作用。	Kaohsiung J Med Sci, 2020, 10.1002/kjm2.12281
S5211	4-Aminosalicylic acid 4-Aminosalicylic acid (Para-aminosalicylic acid, Aminosalicylic acid, 4-aminosalicylate)是一种抗结核药，对结核杆菌具有抑菌活性。
S4833	Cefoxitin sodium Cefoxitin Sodium is the sodium salt form of cefoxitin, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.
S4536	Nitrofurantoin Nitrofurantoin (Macrodantin, Furadantine, Furadonine) 是一种用来治疗膀胱感染的抗菌素。抑制细菌DNA、RNA和细胞壁蛋白合成。
S9135	Artemisic acid Artemisic acid (Artemisinic acid), an amorphane sesquiterpene isolated from Artemisia annua L., has a variety of pharmacological activity, such as antimalarial activity, anti-tumor activity, antipyretic effect, antibacterial activity, allelopathy effect and anti-adipogenesis effect.	ACS Infect Dis, 2020, 10.1021/acsinfecdis.0c00522
S9136	Neochlorogenic acid Neochlorogenic acid (Neochlorogenate, 5-O-Caffeoylquinic acid) is a natural polyphenolic compound found in some types of dried fruits and a variety of other plant sources such as peaches. It shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia.
S5350	Cefpodoxime proxetil Cefpodoxime Proxetil is a third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity.
S5095	Olaquindox Olaquindox (Bisergon, Bayernox, Bayonox, Olachindox)是一种口服的抗细菌剂，被用作动物食品中的添加剂。
S5159	Doxycycline Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum)是一种抗生素，用于治疗由细菌和原生动物引起的多种感染。Doxycycline 也是一种非特异性的 matrix metalloproteinase (MMP) 抑制剂。	Mol Cancer, 2022, 21(1):43 EMBO Rep, 2022, e52984 Cell Rep, 2022, 39(1):110643
S4279	Demeclocycline HCl Demeclocycline HCl 是一种四环素antibiotic可抑制细菌的蛋白合成，用于治疗细菌感染。	J Biol Chem, 2020, 10.1074/jbc.RA119.011633. Sci Rep, 2018, 8(1):7653
S4813	Cefuroxime axetil Cefuroxime axetil, a prodrug of the cephalosporin cefuroxime, is a second generation oral cephalosporin antibiotic with in vitro antibacterial activity against several gram-positive and gram-negative organisms.
S4393	Cephapirin Sodium Cephapirin Sodium (Cefapirin)是cephapirin的钠盐形式，是一种半合成的第一代头孢菌素抗生素，对革兰氏阴性细菌和革兰氏阳性细菌都有效。
S4547	8-Hydroxyquinoline 8-Hydroxyquinoline (8-Oxychinolin, 8-Quinolinol, Oxine) 是一种具有轻度抑制真菌、细菌、驱虫、杀伤阿米巴原虫特性的防腐剂。也被用作金属螯合剂、放射性铟的载体用于诊断治疗。
S5354	Cefteram pivoxil Cefteram Pivoxil is the pivalate ester prodrug of cefteram, a semi-synthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity.
S3280	Linderene Linderene (Lindenenol) 是从Lindera pulcherrima中分离出来的呋喃倍半萜类，具有抗菌和抗氧化活性。
S4550	Azelaic acid Azelaic acid (Nonanedioic acid, Finacea, Azelex, Anchoic acid)是一种通过油酸臭氧分解而来的有机化合物，具有抗菌、消除粉刺、抗氧化活性。
S4844	Cefcapene Pivoxil Hydrochloride Cefcapene Pivoxil is the pivalate ester prodrug form of cefcapene, a semi-synthetic third-generation cephalosporin with antibacterial activity.
S4553	Bronopol Bronopol (2-bromo-2-nitropropane-1,3-diol)是一种抗细菌剂，在化妆品行业被用作防腐剂。
S5007	Delamanid Delamanid (OPC-67683)是一种新型的抗肺结核药物，具有良好的胞内杀菌活性，在细胞中具有高积累率。	Front Immunol, 2021, 12:796677
S5863	Metronidazole Benzoate Metronidazole Benzoate (Benzoyl metronidazole)是metronidazole的苯甲酸酯形式。Metronidazole是一种合成的硝基咪唑衍生物，具有抗原生动物和抗细菌活性。
S4522	Dehydroacetic acid Dehydroacetic acid (Biocide 470F, Methylacetopyronone)是一种有机化合物，主要用作杀菌剂。
S4408	Procodazole Procodazole (Propazol, 2-Benzimidazolepropionic acid, 3-(1H-benzimidazole-2) propanoic acid)可用作增效剂，对病毒和细菌感染具有非特异性活性免疫保护作用。
S4565	Diiodohydroxyquinoline Diiodohydroxyquinoline (Iodoquinol) 是一种局部药物，喹啉衍生物，具有抗菌特性。
S5456	Isobavachalcone Isobavachalcone (Corylifolinin), a naturally occurring chalcone compound derived from the seeds of Psoralea corylifolia L., has long been used in traditional Chinese medicine as anthelmintic, antibacterial, aphrodisiac, astringent and antiplatelet agent.
S0906	6-Methoxydihydroavicine 6-Methoxydihydroavicine (6-Methoxy Dihydrosanguinarine) 是一种从是博落回果实中分离得到的生物碱。

目录号	产品描述	文献引用
S3021	Rimonabant (SR141716) Rimonabant (SR141716)是一个大脑中心大麻素受体（CB1）特异性口服拮抗剂。在hCB1转染HEK293细胞中IC50浓度为13.6 nM，EC50浓度为17.3 nM。Rimonabant也是一种acyl CoA:cholesterol acyltransferases(ACAT) 1和2的双重抑制剂并且可抑制分支杆菌的MmpL3。	Nat Commun,2020, 11(1):5962 Sci Rep,2020, 10(1):15556 Microbiol Immunol,2020, 10.1111/1348-0421.12777
S1162	Pretomanid (PA-824) PA-824是一种抗肺结核药，作用于tuberculosis，MIC为<1 μg/mL。Phase 2。
E0365^New	Fucoidan Fucoidan是从海洋褐藻中提取的阴离子硫酸化多糖，具有广泛的生物活性，包括抗炎、抗癌、抗病毒、抗氧化、抗凝、抗血栓、抗血管生成和抗幽门螺杆菌等。
E0052^New	Merafloxacin Merafloxacin (CI-934) 是一种氟喹诺酮类抗菌剂，可抑制 SARS-CoV-2 和其他 β 冠状病毒的 -1 移码效率。
E0010^New	Hypocrellin A Hypocrellin A (HA) 是一种从 Shiraia bambusicola 中分离的苝醌，显示出抗病毒、抗菌和抗癌的活性。Hypocrellin A 还是 PKC 的选择性和有效抑制剂。
S1677	Chloramphenicol Chloramphenicol (Chloromycetin)是通过抑制蛋白质的合成的抑菌剂。	EMBO Rep,2021, e53081 Cell Rep,2021, 34(3):108631 Oncotarget,2018, 9(40):26086-26095
S2457	Clindamycin HCl Clindamycin HCl 是Clindamycin的水合盐酸盐，是一种半合成的抗生素。	Proc Natl Acad Sci U S A,2016, 113(50):14408-14413
S2908	Hygromycin B Hygromycin B (Hygrovetine)是选择性抗生素，有效作用于大多数细菌，真菌，和更高等的真核生物，通过干扰易位，抑制蛋白合成，造成70S核糖体的错译。	Autophagy,2021, 1-17 PLoS Pathog,2021, 17(4):e1009530 Cell Res,2020,
S1762	Pyrazinamide Pyrazinamide (Pyrazinoic Acid Amide) 是一种治疗肺结核的药物。
S1791	Bacitracin Zinc Bacitracin是一种抗生素，能够干扰C55-isoprenyl pyrophosphate的去磷酸化，C55-isoprenyl pyrophosphate是一种膜载体分子，参与转运构成肽聚糖细菌细胞壁内膜外部成分。Bacitracin抑制甲硫啡肽中Tyr的裂解，IC50为10 μM。
S1618	Sulfameter Sulfameter 是一种长效的磺胺类抗菌药。
S1685	Sulfanilamide Sulfanilamide是细菌酶中二氢喋呤合成的适度竞争性抑制剂，IC50为320 μM。
S1881	Protionamide Protionamide (Prothionamide, 1321-TH) 用于治疗肺结核的一种药。	Mol Imaging Biol,2021, 10.1007/s11307-021-01689-8
S3295	Taxifolin 7-rhamnoside Taxifolin 7-rhamnoside (TR, Taxifolin 7-O-rhamnoside, Taxifolin 7-O-α-L-rhamnoside) 是一种从 Hypericum japonicum 中分离出的类黄酮，其具有对抗耐甲氧西林金黄色葡萄球菌 (MRSA).的临床分离株的抗菌活性。
S5199	Oxytetracycline hydrochloride Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride 是一种抗生素，会干扰细菌产生必需蛋白质的能力。	Front Microbiol,2016, 7:1765
S4490	Tetracycline Tetracycline (TC) 是一种广谱的抗生素，对多种微生物具有活性，包括革兰氏阳性和革兰氏阴性细菌、衣原体、支原体、立克次氏体和原生动物寄生虫。
S2830	Clindamycin Clindamycin通过作用于50S ribosomal subunits（50S核糖体亚基）而抑制蛋白合成。
S9226	Steviolbioside Steviolbioside (CCRIS-6025), a natural sweetener, exhibits moderate antituberculosis activity against M. tuberculosis strain H37RV in vitro.
S5186	Cefpiramide Cefpiramide (Cefpiramide acid, Cefpiramido, Cefpiramidum, WY-44635, SM-1652) 是一种具有广谱抗菌活性的假单胞菌活性头孢菌素。
S5008	Ciprofloxacin hydrochloride Ciprofloxacin (CPX, Cetraxal, Ciloxan, Cipro, Bay-09867) hydrochloride 是一种氟喹诺酮盐酸盐，一种具有广谱抗菌活性的β-二酮类抗生素。Ciprofloxacin 是细菌 DNA gyrase (一种 Type II topoisomerases 亚型) 的抑制剂。
S3496	Lefamulin acetate (Xenleta) Lefamulin acetate (Xenleta, BC-3781 acetate) 是一种截短侧耳素抗生素，用于 community-acquired bacterial pneumonia (CABP) 的治疗。Lefamulin acetate 通过与 50S bacterial ribosome 的肽基转移酶中心结合来抑制蛋白质合成，从而阻止了转移RNA与肽转移的结合。
S5495	Ceftiofur sodium Ceftiofur sodium 是一种半合成的、β-内酰胺酶稳定的广谱头孢菌素，具有抗菌活性。
S3499	Monocaprylin Monocaprylin (2,3-dihydroxypropyl octanoate, Monoctanoin, 1-Octanoyl-rac-glycerol, MC) 对金黄色葡萄球菌和大肠杆菌具有优异的抗菌活性。
S7550	Erythromycin Cyclocarbonate Erythromycin Cyclocarbonate，红霉素的衍生物，通过结合于50S核糖体抑制细菌蛋白质合成。
S4861	Oxindole Oxindole (2-indolone, 2-Oxindole, Indolin-2-one)是芳香族杂环有机化合物，当剂量过量时，可引起镇静、肌无力、低血压和昏迷。
S4647	Cefmenoxime hydrochloride Cefmenoxime (SCE-1365), 肠杆菌科的有效抑制剂，是一种头孢菌素抗生素，通常用于静脉注射或肌内注射。
S6867	Glyceryl monocaprate (Monocaprin) Monocaprin (Glyceryl caprate)是癸酸的1一甘油酯，对包膜病毒、某些细菌和白色念珠菌具有抗菌的活性。
S4602	Acetohydroxamic acid Acetohydroxamic acid (N-Hydroxyacetamide, Methylhydroxamic acid, Acetic acid\|oxime, Lithostat) 是尿素酶抑制剂。在尿液中，它可作为细菌酶尿素酶的拮抗剂。
S6549	PBTZ169 PBTZ169 (macozinone)是DprE1的不可逆性抑制剂，是一种抗生素。	Cell Death Dis,2019, 10(4):319
S6584	Amdinocillin Amdinocillin (Mecillinam, Coactin, FL 1060) 是一种β-内酰胺抗生素，具有广泛的抗菌活性。Amdinocillin 单独可对许多革兰氏阴性菌都有活性。
S0147	KKL-10 KKL-10 是一种 ribosome rescue 的抑制剂，对细菌具有优异的广谱抗菌活性。
S4307	Auranofin Auranofin (Ridaura, SKF-39162) 是一种 thioredoxin reductase (TrxR) 的抑制剂，在无细胞分析中对纯化的幽门螺杆菌TrxR的IC50值为88 nM。Auranofin 具有抗癌活性，在1.2 μM浓度下可以完全抑制细菌的生长。Auranofin 是一种FDA批准的含金化合物，用于治疗类风湿关节炎。	Oncotarget,2018,
S4983	Sorbic acid Sorbic acid (2,4-Hexadienoic acid) is a naturally occurring compound that originated from the unripe berries of the Rowan Tree. It inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division).
S4198	Aminothiazole Aminothiazole作为甲状腺抑制剂，具有抗菌活性。	J Electroanal Chem (Lausanne),2020, 878:114733
S3710	Fosfomycin calcium Fosfomycin (phosphomycin, phosphonomycin) 是一种杀菌剂，可通过使UDP-N-acetylglucosamine-3-enolpyruvyltransferase失活而一直细菌细胞壁形成。Fosfomycin可通过甘油磷酸盐转运蛋白进入细胞壁。
S5166	Benzoyleneurea Benzoyleneurea (2,4-Dihydroxyquinazoline, Quinazolinedione, Quinazoline-2,4-diol) scaffold is used in the synthesis of novel protein geranylgeranyltransferase-I inhibitors.
S6090	JFD01307SC JFD01307SC ([(1,1-dioxidotetrahydrothien-3-yl)amino]acetic acid)对结核分枝杆菌 M.tuberculosis 具有活性，最低抑菌浓度 (MIC) 范围为 8-16 µg/ml。JFD01307SC 可能靶向参与谷氨酰胺 (glutamine) 生物合成的酶。
S4105	Closantel Sodium Closantel Sodium是革兰氏阳性的抗菌活性抑制剂，抑制KinA/Spo0F系统，IC50为3.8 μM。
S4106	Closantel Closantel (R-31520) 是革兰氏阳性的抗菌活性抑制剂，抑制KinA/Spo0F系统，IC50为3.8 μM。
S6464	Ftaxilide Ftaxilide是一种新型的抗痨药。
S0195	Walrycin B Walrycin B 是一种抗菌化合物，是一种靶向WalR反应调节剂的 WalR 的有效抑制剂。
S4780	7-Methoxy-4-methylcoumarin 7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label.
S5201	Acetylisovaleryltylosin Tartrate Acetylisovaleryltylosin tartrate (AK105039)是一种具有抗菌作用的大环内酯物，对革兰氏阳性细菌具有抑制活性。
S4425	Rifamycin S Rifamycin S 是一种quinone和抗 Gram-positive bacteria(包括MRSA) 的抗生素，是一种用于治疗肺结核和麻风病的临床药物。Rifamycin S 可产生 reactive oxygen species (ROS)，并抑制微粒体脂质过氧化 microsomal lipid peroxidation。
S4436	Pleuromutilin Pleuromutilin (Drosophilin B, Mutilin 14-glycolate) 是新型抗生素的先导化合物，它通过结合细菌的50S核糖体亚基来抑制细菌蛋白质的合成。
S7739	Telacebec (Q203) Telacebec (Q203, IAP6) 是一种新型抗结核药物，通过抑制分枝杆菌细胞色素 bc1 复合物来靶向结核分枝杆菌（Mycobacterium tuberculosis）细胞能量的产生。Telacebec 对结核分枝杆菌 H37Rv 具有活性，在培养基中的 MIC50 为 2.7 nM。
S4404	Pasiniazid Pasiniazid，由isoniazid和4-aminosalicylic acid组成，用于治疗肺结核患者。
S4854	Bedaquiline fumarate Bedaquiline fumarate (TMC-207), an oral diarylquinoline, is a bactericidal antimycobacterial drug. It is a proton-translocating ATP synthetase inhibitor.	Adv Healthc Mater,2022, e2102117

目录号	产品描述	文献引用	实验数据
S1373	Daptomycin (LY146032) Daptomycin (LY146032)是一种新型抗生素，在体外对革兰氏阳性菌具有快速的杀菌活性。	J Phys Chem B, 2021, 125(22):5775-5785 Sci Adv, 2020, 6(34):eaba8968 Front Microbiol, 2020, 21;11:646	Same experiment as in Figure 2 with fluorescent daptomycin shown as confocal images. A 7/3 DOPC/DOPG GUV (including 1% Rh-PE) was introduced at time zero into a solution containing 1 uM daptomycin with 0.5 uM BODIPY-daptomycin and 1 mM Ca2+. To show colocalization of lipid and peptide in aggregates, confocal images were taken: red for RH-PE and green for BODIPY-daptomycin. As the protrusion length decreased, aggregates appeared on the GUV surface containing both lipid and peptide. The scale bar is 10 um.
S1097	BTZ043 Racemate BTZ043 Racemate是一种decaprenylphosphoryl-β-D-ribose 2’-epimerase的抑制剂，是一个可以杀死结核杆菌的新的抗分支杆菌的药物。	Drug Deliv Transl Res, 2021, 11(4):1766-1778 J Med Chem, 2020, 28;63(10):5367-5386 Biochem Pharmacol, 2019, 162:41-54
S1403	Tigecycline (GAR-936) Tigecycline (GAR-936) 是一种甘氨酰环素类抗生素，具有抑菌作用，是一种蛋白质合成的抑制剂，通过与细菌的 30S核糖体亚基结合，从而在原核翻译过程中阻止氨酰tRNA进入核糖体的A位点。Tigecycline 可通过下调PI3K-AKT-mTOR途径诱导自噬。	iScience, 2021, 24(11):103350 Biomolecules, 2020, 10(10)E1395 Aging (Albany NY), 2020, 12(12):11364-11385	CHX blocked Pim-1 AUG isoform translocation from the cytosol to mitochondria and led to reduced pBADS112. Cox-2 was examined to assess the effect of tigecycline on mitochondrial translation. Cy-Cox-2: cytoplasmic Cox-2; Mt-Cox-2: mitochondrial Cox-2.
S1741	Rifabutin (LM427) Rifabutin (LM427, Ansamycin) 是一种半合成的Ansamycin 抗生素，具有有效的抗分枝杆菌特性。	Antibiotics (Basel), 2020, 9(2) Antimicrob Agents Chemother, 2020, AAC.00363-20
S1370	Biapenem Biapenem (L-627, LJC10627) 是一种碳青霉烯类抗生素，抑制了革兰氏阳性菌以及革兰氏阴性菌的活性。
S1399	Teicoplanin Teicoplanin (Teichomycin) 是一种预防用的抗生素。	ACS Appl Mater Interfaces, 2020, 12(14):16150-16158 Clin Exp Dent Res, 2016, 2(1):35-43
S1505	Aztreonam Aztreonam (SQ 26776) 是一种合成的单环β-内酰胺类抗生素。	PLoS Pathog, 2016, 12(10):e1005932 Expert Opinion on Orphan Drugs, 2013, 1(7):549-556
S1768	Cefditoren Pivoxil Cefditoren Pivoxil (ME-1207) 是一种广谱的抗生素，用于治疗格兰仕阳性菌和阴性菌感染。
S1839	Chloroxine Chloroxine是一种人工合成的抗菌化合物，加入洗发液中，有效治疗头皮屑和脂溢性皮炎。	Hum Mol Genet, 2020, ddaa244 Front Microbiol, 2020, 10:2936
S1605	Cefdinir Cefdinir (FK 482, PD 134393, CI-983) 是一种杀菌抗生素。
S1502	Cephalexin Cephalexin (Cefalexin)是可以治疗许多细菌感染的抗生素。	Clin Cancer Res, 2018, 24(3):659-673 Theranostics, 2017, 7(7):2092-2107 Blood Cancer J, 2017, 10.1038/bcj.2017.61
S1835	Azithromycin (CP-62993) Azithromycin (CP-62993, XZ-450)是一种抑制蛋白合成的抗生素，用于细菌感染的治疗。	J Cell Biochem, 2022, 10.1002/jcb.30213 Hum Cell, 2022, 10.1007/s13577-022-00671-y Hum Cell, 2021, 34(6):1911-1918
S1773	Oxytetracycline (Terramycin) Oxytetracycline(Terramycin) 是第二个被发现的广谱四环素类抗生素。	Sci Rep, 2018, 8(1):7653 Front Microbiol, 2016, 7: 1765	Effect of FDA approved drugs on EBOV transfected donor and recipient immune cells. (A) Varying concentrations of Cambinol and Esomepraole (1 nM, 1 μM, 10 μM), Oxytetracycline (1 nM, 10 nM, 10 μM), and DMSO (0.00001, 0.0001, 0.001%) treatments were administered to VP40-transfected 293T cells, followed by incubation for 3 days. Supernatant was centrifuged to remove cellular material and subsequently incubated for 72 h at 4°C with 20 μL of 30% slurry of NT80/82 beads. The NT pellet was washed twice with PBS and resuspended in SDS Laemmli buffer, followed by Western blot analysis for levels of exosomal markers CD63 and Alix. Actin levels were also analyzed. Mid-log phase EVTR2C cells (containing VP40) were treated with either low (0.1 μM), medium (1 μM), or high (10 μM) concentrations of Oxytetracycline and incubated for 5 days along with untreated 293T cells. Cell-free supernatants were harvested, filtered, and used to treat CEM (B), Jurkat (C), and U937 (D) cells. Cells were incubated for 5 days and assayed with CellTiter-Glo for viability. Statistical significance was determined using two-tailed student’s t-test with all groups compared to the untreated 293T cell control groups. RLU, Relative Luminescent Units. ∗p < 0.05, ∗∗∗p < 0.001.
S2568	Neomycin sulfate Neomycin sulfate属于氨基糖苷类抗生素。	Mol Cell, 2020, 22 pii: S1097-2765(20)30231-8
S2420	Aloperine Aloperine是提取自苦参植物，如Sophora alopecuroides L的生物碱，具有抗炎，抗菌，抗病毒,和抗肿瘤的特性。	Cancer Cell Int, 2021, 21(1):662 Tissue Cell, 2021, 74:101706 J Cancer Res Clin Oncol, 2020, 10.1007/s00432-020-03157-2
S2565	Amoxicillin Sodium Amoxicillin Sodium (Clavulanate) 是一种中等谱，溶菌，β-内酰胺类抗生素。	ChemMedChem, 2022, e202200043 PLoS Comput Biol, 2020, 16(12):e1008489 Toxicol Appl Pharmacol, 2015, 285(1):51-60
S2544	Cefprozil hydrate Cefprozil hydrate 是第二代头孢菌素类抗生素。
S2563	Oxacillin sodium monohydrate Oxacillin sodium monohydrate (Methicillin)是一种抗菌剂，是一种窄谱，青霉素类的β-内酰胺类抗生素。
S3129	Trimethoprim Trimethoprim (BW 56-72, NIH 204, NSC-106568) 是一种抑制细菌的抗生素，主要用于预防和治疗尿路感染。
S1915	Sulfamethoxazole Sulfamethoxazole 是磺胺类抑制细菌的抗生素，IC50为2.7 μM。
S2575	Vancomycin HCl Vancomycin HCl 是Vancomycin的盐酸盐，是一种窄谱的糖肽类抗菌剂。	Elife, 2021, 10e64237 Gut Microbes, 2020, 12(1):1-20 Oncotarget, 2018, 9(40):26086-26095
S2543	Ceftiofur HCl Ceftiofur HCl (U-67279A)是Ceftiofur的盐酸盐，是一种广谱头孢菌素。
S1916	Sulfisoxazole Sulfisoxazole (NU-445) 是一种磺胺类抗菌药，具有一个恶唑取代基。
S3195	Azlocillin sodium salt Azlocillin sodium salt是一种酰基氨苄青霉素，具有广谱抗菌作用。
S4004	Ethambutol 2HCl Ethambutol 2HCl (CL40881)是一种抗分枝杆菌抑菌剂, 通过抑制阿拉伯糖基转移酶来干扰细胞壁形成。	Molecules, 2019, 25(1)
S4146	Bacitracin Bacitracin是由Bacillus subtilis var生物体产生的相关环状多肽组成的混合物，通过干扰细胞壁肽聚糖的合成，从而破坏革兰氏阳性和革兰氏阴性细菌。	Onco Targets Ther, 2020, 13:9543-9558 Anal Chem, 2017, 89(16):8501-8508 Chem Res Toxicol, 2017, 30(10):1804-1814
S3015	Amoxicillin Amoxicillin (Amoxycillin) 是一种温和β-内酰胺抗生素，用于治疗敏感菌引起的微生物细菌感染。	ChemMedChem, 2022, e202200043 PLoS Comput Biol, 2020, 16(12):e1008489 Toxicol Appl Pharmacol, 2015, 285(1):51-60
S1957	Sulfamethizole Sulfamethizole 是一种磺胺类抗菌剂。
S4093	Bismuth Subcitrate Potassium Bismuth Subcitrate是一种抗生素，用于治疗感染幽门螺旋杆菌的胃溃疡。	Cell Rep, 2022, 38(6):110359 J Clin Invest, 2020, 130(7):3901-3918
S3122	Amikacin hydrate Amikacin hydrate 是一种氨基糖甙类抗生素，用于治疗不同类型的细菌感染。	Molecules, 2019, 25(1)
S3133	Sulfamethazine Sulfamethazine是一种磺胺类抗菌药,是一种用来治疗支气管炎，前列腺炎以及尿道感染的抗生素。Sulfamethazine 通过抑制二氢叶酸合成酶活性来阻断二氢叶酸合成。此外， sulfamethazine 是一种对氨基苯甲酸(PABA)的结构类似物和竞争性拮抗剂，可以抑制正常的细菌利用PABA 来合成叶酸，而叶酸是一种重要的DNA合成代谢物。
S1855	Pefloxacin Mesylate Pefloxacin Mesylate是一种合成的化疗药物和抗菌剂，IC50为6.7 nM。	J Biol Chem, 2019, 294(49):18624-18638
S3179	Carbenicillin disodium Carbenicillin (BRL-2064) 是一种半合成的青霉素抗生素，可以干扰革兰氏阴性菌细胞壁的合成，具有低毒性。
S3193	Ticarcillin sodium Ticarcillin (AB 2288, BRL 2288) 是一种半合成的抗生素，对多种革兰氏阳性和阴性需氧以及厌氧菌具有广谱杀菌活性。
S5227	Erythromycin thiocyanate Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits and inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
S5352	Cefminox Sodium Cefminox Sodium (Meicelin, MT-141) is the sodium salt form of cefminox, a semi-synthetic, second-generation, beta-lactamase-stable cephalosporin with antibacterial activity.
S6235	Sodium dehydroacetate Sodium dehydroacetate是无水醋酸的钠盐形式。无水醋酸是一种杀菌剂，通常被用作食品防腐剂。
S3621	Pazufloxacin mesylate Pazufloxacin Mesylate (T-3762, Pazucross)，也被称作是Pazucross和T-3762，是一种喹诺酮类抗菌剂，用于多种感染的治疗。
S5560	Midecamycin Midecamycin (Espinomycin A, Medecamycin A1, Platenomycin B1, Rubimycin, Turimycin P3) is a naturally occuring macrolide antibiotic that acts by inhibiting bacterial protein synthesis.
S5406	Sultamicillin Tosylate Sultamicillin Tosylate is the tosylate salt of the double ester of sulbactam plus ampicillin. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would otherwise be resistant.
S5048	Fosfomycin Disodium Fosfomycin (Phosphonemycin)是一种具有杀菌活性的，低分子量、广谱抗生素，通过抑制细胞壁合成的早期阶段，对一些细菌具有潜在活性，如多药耐药的革兰氏阴性细菌。
S5051	Pipemidic acid Pipemidic acid (Acido pipemidico)是一类吡啶并嘧啶类抗生素，是piromidic acid的衍生物，对革兰氏阴性和某些革兰氏阳性细菌具有活性。	Hum Mol Genet, 2020, ddaa244
S4576	Sulfabenzamide Sulfabenzamide (Sultrin, N-Sulfanilylbenzamide) 是一种抗菌剂，它通过多种途径也可以发挥抗肿瘤效果。
S5353	Cefpiramide sodium Cefpiramide sodium (CPMS, SM-1652,wy-44635) is an anionic β-lactam antibiotic. It exhibits antibacterial activity against gram-positive and gram-negative bacteria, in particular, to Pseudomonas aeruginosa, which can result in achronic life-threatening infection in the lungs of cystic fibrosis patients.
S4848	Dalbavancin Dalbavancin (Zeven, BI 397, MDL 63397)是一种脂糖肽类抗生素，对革兰氏阳性菌，如多种葡萄状球菌，具有杀菌活性。
S5081	Ceforanide Ceforanide是一种新型头孢菌素，具有抗细菌活性，具有较长的消除半衰期。
S5951	Cefoxitin Cefoxitin是一种β-内酰胺、头孢菌素抗生素，具有杀菌活性。
S5356	Ceftiofur Ceftiofur is a semisynthetic, beta-lactamase-stable, broad-spectrum cephalosporin with antibacterial activity.	Vet J, 2018, 234:24-26
S5012	Octenidine Dihydrochloride Octenidine是一种阳离子型表面活性剂，对革兰氏阳性和阴性的细菌具有活性。
S3623	Ceftibuten dihydrate Ceftibuten Dihydrate is the dihydrate form of ceftibuten, a semisynthetic, beta-lactamase-stable, third-generation cephalosporin with antibacterial activity.
S4850	Flucloxacillin sodium Flucloxacillin sodium (Floxacillin sodium) is the sodium salt of flucloxacillin, a penicillin antibiotic used to treat bacterial infections.
S9224	Dehydroandrographolide Succinate Dehydroandrographolide succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, has antibacterial and antiviral effects.
S4846	Meropenem Trihydrate Meropenem is a broad-spectrum antibacterial agent of the carbapenem family with a broad spectrum of in vitro activity against Gram-positive and Gram-negative pathogens.
S5533	Tobramycin sulfate Tobramycin sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity.	Oncotarget, 2018, 9(40):26086-26095
S4594	Cephalothin sodium Cephalothin (Cefalotin, Cephalotin) sodium 是一种半合成的β-内酰胺类抗生素，第一代头孢菌素抗生素，具有杀菌活性。Cephalothin与位于细菌细胞壁内膜的青霉素结合蛋白（PBP）结合并使之失活。
S5941	Besifloxacin Besifloxacin是第四代氟喹诺酮类眼部抗生素，用于治疗细菌性结膜炎。
S4880	Cefathiamidine Cefathiamidine is the first generation of cephalosporin antibacterial used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis.
S5268	Solithromycin Solithromycin (CEM-101, OP-1068), belonging to the well-known class of macrolide antibiotics that also includes azithromycin, is a potent bacterial protein synthesis inhibitor.
S1617	Sulfapyridine Sulfapyridine 是一种磺胺类抗菌药。
S5332	Cefquinome sulfate Cefquinome sulphate is a veterinary, parenteral, and fourth-generation cephalosporin. Its antimicrobial potency and extensive antibacterial spectrum result from the introduction of a methoxyimino-aminothiazolyl moiety into the acyl side chain.
S5278	Tedizolid (TR-700) Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.
S4029	Colistin Sulfate Colistin (Polymixin E)是一种环状阳离子十肽，链接到脂肪酸侧链，属于一组结构类似的细菌抗微生物肽。	Front Pharmacol, 2021, 12:744494 Biogerontology, 2016, 17(5-6):907-920
S2052	Oxytetracycline Dihydrate Oxytetracycline Dihydrate 是一种处方抗生素，干扰细菌产生必需蛋白质的能力。	Front Microbiol, 2016, 7:1765
S5532	Erythromycin estolate Erythromycin (Lubomycine B), a naturally occurring macrolide, is derived from Streptomyces erythrus. It inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
S5535	Moxifloxacin Moxifloxacin is an antibiotic used to treat a number of bacterial infections, active against Mycobacterium tuberculosis in vitro.	Transl Vis Sci Technol, 2018, 7(2):11 J Pharmacol Toxicol Methods, 2017, 90:39-47 Circ Arrhythm Electrophysiol, 2016, 9(4):e003655
S5625	Ammonium lactate Ammonium lactate (Lac-hydrin) is the ammonium salt of lactic acid with mild anti-bacterial properties.
S4869	Sulfamethoxazole sodium Sulfamethoxazole sodium是一种用于治疗细菌感染的抗生素。
S5054	Rifamycin sodium salt Rifamycin sodium is an antibacterial drug used for treatment of mycobacterium infections.
S5491	Lomefloxacin Lomefloxacin is a fluoroquinolone antibiotic used to treat bacterial infections.
S5331	Ceftezole sodium Ceftezole Sodium (Celoslin sodium, Falomesin sodium) is the sodium salt form of ceftezole, a semi-synthetic first-generation cephalosporin with antibacterial activity.
S4595	Cefazolin Sodium Cefazolin Sodium (cefazoline, cephazolin, Ancef)是一种半合成的头孢菌素类似物，具有广谱抗菌作用，抑制细菌细胞壁的合成。它能达到较高的血清水平，通过尿液排泄出去。
S5936	Cefazolin Cefazolin是一种半合成的头孢菌素，具有广谱的抗菌作用，抑制细菌细胞壁的合成。它可达到高血清水平，通过尿液快速排泄。
S4596	Cefixime Cefixime (Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635) 是一种对于治疗许多细菌感染疾病有用的抗生素。
S4148	Ampicillin Trihydrate Ampicillin Trihydrate (NCI-C56086)是β-内酰胺类抗生素，通过使细菌细胞膜内表面上的转肽酶失活而抑制细菌细胞壁合成（肽聚糖的交联）。	Bone Joint Res, 2020, 16;9(4):152-161
S4875	Cephapirin Benzathine Cephapirin Benzathine是cephapirin的苄星青霉素盐形式。Cephapirin是半合成的、广谱的、第一代头孢菌素，具有抗菌活性。
S4885	Taurolidine Taurolidine (Taurolin, Tauroline, Tauroflex) 是一种合成的、广谱的抗生素，具有抗细菌、抗凝的和潜在的抗血管新生的活性。
S5492	Econazole Econazole is a broad spectrum antimycotic with some action against Gram positive bacteria.	Am J Cancer Res, 2020, 10(1):263-274 Biomol Ther (Seoul), 2020, 25
S4874	Cefazedone Cefazedone (Refosporen, Cefazedonum) 是一种半合成的一代头孢菌素，具有抗细菌活性。
S9466	Methenamine Hippurate Methenamine Hippurate是methenamine的马草酸盐形式，是一种前药和惰性弱碱，在酸性尿液中会水解成甲醛。Methenamine Hippurate是Hiprex药物的成分，具有抗菌活性。
S9292	Dictamnine Dictamnine, a natural plant product, has been reported to have antimicrobial activity against bacteria and fungi.
S5296	Cephradine monohydrate Cefradine is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.
S5487	Cefoperazone sodium Cefoperazone Sodium is the sodium salt form of cefoperazone, which is a semi-synthetic, broad-spectrum, beta-lactamase resistant antibiotic with bactericidal activity.
S4822	Silver Sulfadiazine Silver sulfadiazine是一种杀菌剂，对很多革兰氏阴性和阳性的细菌以及酵母都十分有效。
S5736	Benzathine penicilline Benzathine penicilline (Benzathine penicillin G) is an antibiotic useful for the treatment of a number of bacterial infections.
S1884	Sparfloxacin Sparfloxacin (AT-4140, CI-978, PD 131501)是一种喹诺酮类抗生素，具有广谱有效的抗菌活性。
S2385	Hordenine Hordenine是一种苯乙胺生物碱具有抗菌特性。
S4634	Sodium sulfadiazine Sodium Sulfadiazine (Sulfadiazin-natrium)是sulfadiazine的钠盐形式，一种具有中效抑菌作用的合成sulfanilamide衍生物。
S4959	Skatole Skatole (3-methylindole, Scatole)是一种具有轻度毒性的白色结晶有机化合物，天然存在于排泄物中，具有相当广泛的抑菌作用。
S5291	sulfaisodimidine Sulfaisodimidine (Sulfamethin) is a sulfonamide antibacterial.
S5235	Cefodizime Cefodizime (CEF, CDZ) 是一种氨基噻唑基头孢菌素，具有广泛的抗菌活性。
S5417	Spectinomycin dihydrochloride pentahydrate Spectinomycin dihydrochloride pentahydrate (Trobicin) 是一种广泛使用的抗生素，可通过阻止信使RNA的易位和核糖体上的转移RNA来抑制细菌蛋白质的合成。
S3644	Sulfamonomethoxine Sulfamonomethoxine is a long-acting sulfonamide antibacterial agent and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
S5298	Amoxicillin trihydrate Amoxicillin (Amoxil, Amoxipen, Moxaline) is a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity.	ChemMedChem, 2022, e202200043 PLoS Comput Biol, 2020, 16(12):e1008489
S5546	Sulfacetamide Sulfacetamide (Acetosulfamine) is a synthetic sulfanylacetamide derivative with bacteriostatic activity. It is an anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
S4179	Mezlocillin Sodium Mezlocillin Sodium是青霉素的beta-内酰胺类抗生素，通常用于治疗革兰氏阳性菌引起的感染。
S4060	Erythromycin Ethylsuccinate Erythromycin Ethylsuccinate, 是一种口服的大环内酯类抗菌素，由链霉菌产生, 可以可逆的结合细菌50S 核糖体并抑制蛋白合成。
S5515	Penicillin G Procaine Procaine benzylpenicillin (Procaine benzylpenicillin), also known as Procaine benzylpenicillin, is an antibiotic useful for the treatment of a number of bacterial infections.
S5289	Ceftezole Ceftezole (Celoslin, Falomesin) is a semi-synthetic first-generation cephalosporin with antibacterial activity.
S3655	Cefepime Dihydrochloride Monohydrate Cefepime is a cephalosporin antibacterial drug used to treat pneumonia, urinary tract, skin, and intra-abdominal infections.	ACS Chem Neurosci, 2021, 10.1021/acschemneuro.1c00608
S5637	Cefotiam Hexetil Hydrochloride Cefotiam Hexetil Hydrochloride is the hydrochloride salt of cefotiam hexetil. Cefotiam is a semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity.
S4541	Triclosan Triclosan (Irgasan, Cloxifenolum) 是在化妆品和香皂中被用作防腐剂的二苯醚衍生物。它具有抑菌作用。	FASEB J, 2019, 10.1096/fj.201802603RR Onco Targets Ther, 2018, 11:2945-2954
S5638	Cefozopran hydrochloride Cefozopran Hydrochloride is the hydrochloride salt form of cefozopran, a semi-synthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity.
S5644	Ceftriaxone Sodium Ceftriaxone Sodium is the sodium salt form of ceftriaxone, a beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity.
S4720	Cefotaxime Cefotaxime是第三代头孢菌素抗生素，对革兰氏阴性菌和阳性菌具有广谱活性。
S8871	Omadacycline tosylate Omadacycline tosylate 是氨甲环素类抗生素，对革兰氏阳性和阴性的需氧菌以及一些厌氧菌具有抗菌活性。
S5330	Amikacin Sulfate Salt Amikacin (BAY 41-6551) sulfate 是卡那霉素的半合成类似物，是一种氨基糖苷类抗生素，对大多数革兰氏阴性细菌，包括对庆大霉素和妥布霉素耐药的菌株，都具有非常强的活性。
S5420	Clindamycin alcoholate Clindamycin alcoholate is a crystallizable compound of Clindamycin with alcohol. Clindamycin is a semisynthetic lincosamide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
S4750	Sulfacetamide sodium salt hydrate Sulfacetamide是一种磺胺类抗生素，通过抑制dihydropteroate synthase(DHPS)阻滞二氢叶酸的合成。Sulfacetamide是细菌para-aminobenzoic acid (PABA)的竞争性抑制剂，PABA是细菌合成叶酸所必需的。
S9046	Berberine Berberine (Umbellatine), an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic.	Front Pharmacol, 2021, 12:632201 Brain Res Bull, 2021, 177:22-30 Biology (Basel), 2021, 10(3)250
S3636	Cefadroxil hydrate Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.
S3637	Cefpirome sulfate Cefpirome is a fourth-generation cephalosporin and is considered highly active against Gram-negative bacteria.
S3638	Cefamandole nafate Cefamandole Nafate is the sodium salt form of cefamandole formyl ester. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall, interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
S5440	Berberine Sulfate Berberine sulfate (Umbellatine), an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria, fungi, and protozoa.	Front Pharmacol, 2021, 12:632201 Biology (Basel), 2021, 10(3)250
S3350	Cholesteryl linoleate Cholesteryl linoleate 是一种人鼻液中极性较低的脂质，助力固有的抗菌活性。
S5784	Vancomycin Vancomycin是一种抗生素，用于治疗各种细菌感染。	Gut Microbes, 2020, 12(1):1-20 Oncotarget, 2018, 9(40):26086-26095
S3708	Sulfachloropyridazine Sulfachloropyridazine是一种抗生素，用于治疗多种细菌感染。
S4201	Florfenicol Florfenicol (SCH-25298) 是一种氟化的Thiamphenicol合成类似物，具有广谱的抑菌活性。
S4663	Fusidate Sodium Fusidate Sodium (Fucidin, SQ-16360) 是fusidic acid的钠盐形式，fusidic acid是一种来自于梭链孢菌的抑菌性抗生素，被用来作为局部药物治疗，治疗皮肤感染。
S3709	Furagin Furagin (NF-416, F-35, Akritoin, Furazidin, Furazidine)是一种2-substituted 5-nitrofuran，在化学结构上与已知的抗细菌化合物nitrofurantoin类似，具有抑菌活性。
S4203	Furaltadone HCl Furaltadone HCl是一种抗菌药，治疗球虫病具有明显的疗效。	Eur J Pharmacol, 2018, 828:119-125
S4986	Latamoxef sodium Latamoxef sodium (Moxalactam Disodium, FestamoxinLy, Shiomarin, Ly 127935, 6059 S) is an antibiotic and has anti-bacterial and anti-inflammation effects.
S6411	Nimorazole Nimorazole是一种水溶性的硝基咪唑化合物，具有抗细菌和潜在的放射增敏作用。
S3058	Danofloxacin Mesylate Danofloxacin (CP-76136-27) 是一种喹诺酮类抗菌剂，兽医用药，MIC90为0.28 μM。
S4271	Isepamicin Sulphate Isepamicin Sulphate (Isepamicine, Isepamycin, sch21420) 是一种氨基糖苷类antibiotic，以细菌30S核糖体亚基为靶点抑制细菌蛋白质的合成。
S3672	Cefonicid sodium Cefonicid sodium (Monocid) is a cephalosporin antibiotic. It interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism.
S4213	Dirithromycin Dirithromycin (LY-237216, ASE 136) 是大环内酯类糖肽抗生素，通过与细菌70S核糖体的50S亚基结合，从而抑制肽易位。
S4216	Valnemulin HCl Valnemulin是天然存在的二萜类抗生素pleuromutilin的半合成衍生物，它的作用是抑制肽基转移酶。
S5070	Mupirocin calcium Mupirocin Calcium (Pseudomonic acid A)是mupirocin的钙盐形式。Mupirocin是一种天然的巴豆酸衍生物，提取自荧光假单胞菌，抑制细菌蛋白质合成，被用作一种抗生素。
S6067	2,4-dichlorobenzyl alcohol 2,4-Dichlorobenzyl alcohol是一种温和的防腐剂，能够杀死口喉感染相关的细菌和病毒。
S9099	Orientin Orientin (Lutexin, Luteolin-8-glucoside), isolated from medicinal plants, has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects.
S2335	Oridonin (NSC-250682) Oridonin (Isodonol, Rubescenin, NSC-250682) 是从Rabdosia rubescens中分离的对映贝壳杉烷二萜,是一种具有抗肿瘤、抗细菌和抗感染效果的传统中药。Oridonin 抑制AKT1 和 AKT2的激酶活性，对应的IC50值分别为8.4 μM 和 8.9 μM。	Pharmacol Res, 2022, 178:106188 Int Immunopharmacol, 2022, 102:108387 J Exp Med, 2021, 218(9)e20202637	Histopathological analysis of H460 tumors following combination treatment with oridonin and radiation. Hematoxylin and eosin (H-E) staining and immunohistochemistry for cleaved caspase-3 and γ-H2AX were performed on tumors harvested at 14 days after IR. Representative images of H-E-stained tumors (upper images) and cleaved caspase-3- and γ-H2AX-positive cells (middle images, brown staining) and quantification of cleaved caspase-3 and γ-H2AX-positive staining with six mice in each group (lower plots, means ± SEM) are shown; * p < 0.05.
S5776	Proflavine Proflavine (3,6-Diaminoacridine)是一种消毒抑菌剂，可抑制许多革兰氏阳性菌。它常被用作伤口敷料中的局部杀菌剂。
S6444	Triclocarban Triclocarban是一种常用于个人护理用品中的抗细菌试剂。
S3650	Penicillin V potassium salt Phenoxymethylpenicillin, also known as penicillin V, is an antibiotic useful for the treatment of a number of bacterial infections. It acts by inhibiting the biosynthesis of cell-wall peptidoglycan.
S9328	5,6,7-Trimethoxyflavone 5,6,7-Trimethoxyflavone (Baicalein Trimethyl Ether), methylations of the hydroxyl groups of oroxylin A or baicalein, has various pharmacological activities including antiviral, anticancer and antibacterial.
S5036	Nisin Nisin (Ambicin N) 是一种核糖体合成的肽段，具有广谱的抑菌活性，抑制多种细菌包括食品腐败菌与致病菌。
S3121	Ornidazole Ornidazole (Ro7-0207, NSC 95075)是5-硝基咪唑衍生物，具有抗原虫和抗厌氧菌的抗菌性能。
S5924	Olanexidine Hydrochloride semihydrate Olanexidine (OPB-2045, OPB-2045G)是一种具有杀菌活性的单双胍化合物。
S5410	Chloramphenicol sodium succinate Chloramphenicol Sodium Succinate is the sodium succinate salt form of chloramphenicol, a nitrobenzene derivate and broad-spectrum antibiotic with antibacterial activity.	Oncotarget, 2018, 9(40):26086-26095
S4517	Cefotaxime sodium Cefotaxime sodium salt是第三代头孢菌素抗生素，是一种广谱的、具有抵抗大多数Gram-positive和Gram-negative细菌的抗菌剂。
S9122	Tectorigenin
S4518	Chloroxylenol Chloroxylenol是一种广谱的抗菌类化合物，用来抵抗细菌、藻类、真菌和病毒。
S5209	Enoxacin Sesquihydrate Enoxacin sesquihydrate (Enoxacin hydrate)是一种广谱的6-fluoronaphthyridinone抗菌剂。
S9377	Eugenyl acetate Eugenyl acetate, an aromatic component of clove essential oil, exhibits various pharmacological activities, including antibacterial and anti-virulence activities against drug-resistant A. baumannii clinical isolates.
S3132	Sulfamerazine Sulfamerazine (RP 2632) 是磺胺类抗菌药。
S5208	Ciprofloxacin hydrochloride hydrate Ciprofloxacin Hydrochloride (Ciloxan, Ceprimax, Oftacilox) 是ciprofloxacin的盐酸盐形式，ciprofloxacin是一种抗生素，用于治疗一些细菌感染疾病。
S3065	Amikacin disulfate Amikacin sulfate (BB-K8)是一种半合成，水溶性的卡那霉素氨基糖苷类衍生物，可以结合到细菌30S 核糖体亚基上引起mRNA读取错误从而导致细菌不能合成自身生长所必需的蛋白。
S4523	Dihydrostreptomycin sulfate Dihydrostreptomycin sulfate是氨基糖苷类抗生素，用来在牛、猪和羊中治疗细菌性疾病。Dihydrostreptomycin是链霉素的衍生物。
S5473	Pivmecillinam hydrochloride Pivmecillinam is a β-lactam antibiotic and a prodrug of mecillinam. It has selective activity against Gram-negative bacteria and is used primarily in the treatment of lower urinary tract infections.
S5202	Quinocetone Quinocetone是一种新型的兽用化合物，具有杀菌作用和潜在的抗肿瘤活性。
S4528	Furazolidone Furazolidone是一种合成的硝基呋喃衍生物。对Gram-positive和Gram-negative的细菌具有灭菌或抑菌作用。	Kaohsiung J Med Sci, 2020, 10.1002/kjm2.12281
S5211	4-Aminosalicylic acid 4-Aminosalicylic acid (Para-aminosalicylic acid, Aminosalicylic acid, 4-aminosalicylate)是一种抗结核药，对结核杆菌具有抑菌活性。
S4833	Cefoxitin sodium Cefoxitin Sodium is the sodium salt form of cefoxitin, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.
S4536	Nitrofurantoin Nitrofurantoin (Macrodantin, Furadantine, Furadonine) 是一种用来治疗膀胱感染的抗菌素。抑制细菌DNA、RNA和细胞壁蛋白合成。
S9135	Artemisic acid Artemisic acid (Artemisinic acid), an amorphane sesquiterpene isolated from Artemisia annua L., has a variety of pharmacological activity, such as antimalarial activity, anti-tumor activity, antipyretic effect, antibacterial activity, allelopathy effect and anti-adipogenesis effect.	ACS Infect Dis, 2020, 10.1021/acsinfecdis.0c00522
S9136	Neochlorogenic acid Neochlorogenic acid (Neochlorogenate, 5-O-Caffeoylquinic acid) is a natural polyphenolic compound found in some types of dried fruits and a variety of other plant sources such as peaches. It shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia.
S5350	Cefpodoxime proxetil Cefpodoxime Proxetil is a third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity.
S5095	Olaquindox Olaquindox (Bisergon, Bayernox, Bayonox, Olachindox)是一种口服的抗细菌剂，被用作动物食品中的添加剂。
S5159	Doxycycline Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum)是一种抗生素，用于治疗由细菌和原生动物引起的多种感染。Doxycycline 也是一种非特异性的 matrix metalloproteinase (MMP) 抑制剂。	Mol Cancer, 2022, 21(1):43 EMBO Rep, 2022, e52984 Cell Rep, 2022, 39(1):110643
S4279	Demeclocycline HCl Demeclocycline HCl 是一种四环素antibiotic可抑制细菌的蛋白合成，用于治疗细菌感染。	J Biol Chem, 2020, 10.1074/jbc.RA119.011633. Sci Rep, 2018, 8(1):7653
S4813	Cefuroxime axetil Cefuroxime axetil, a prodrug of the cephalosporin cefuroxime, is a second generation oral cephalosporin antibiotic with in vitro antibacterial activity against several gram-positive and gram-negative organisms.
S4393	Cephapirin Sodium Cephapirin Sodium (Cefapirin)是cephapirin的钠盐形式，是一种半合成的第一代头孢菌素抗生素，对革兰氏阴性细菌和革兰氏阳性细菌都有效。
S4547	8-Hydroxyquinoline 8-Hydroxyquinoline (8-Oxychinolin, 8-Quinolinol, Oxine) 是一种具有轻度抑制真菌、细菌、驱虫、杀伤阿米巴原虫特性的防腐剂。也被用作金属螯合剂、放射性铟的载体用于诊断治疗。
S5354	Cefteram pivoxil Cefteram Pivoxil is the pivalate ester prodrug of cefteram, a semi-synthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity.
S3280	Linderene Linderene (Lindenenol) 是从Lindera pulcherrima中分离出来的呋喃倍半萜类，具有抗菌和抗氧化活性。
S4550	Azelaic acid Azelaic acid (Nonanedioic acid, Finacea, Azelex, Anchoic acid)是一种通过油酸臭氧分解而来的有机化合物，具有抗菌、消除粉刺、抗氧化活性。
S4844	Cefcapene Pivoxil Hydrochloride Cefcapene Pivoxil is the pivalate ester prodrug form of cefcapene, a semi-synthetic third-generation cephalosporin with antibacterial activity.
S4553	Bronopol Bronopol (2-bromo-2-nitropropane-1,3-diol)是一种抗细菌剂，在化妆品行业被用作防腐剂。
S5007	Delamanid Delamanid (OPC-67683)是一种新型的抗肺结核药物，具有良好的胞内杀菌活性，在细胞中具有高积累率。	Front Immunol, 2021, 12:796677
S5863	Metronidazole Benzoate Metronidazole Benzoate (Benzoyl metronidazole)是metronidazole的苯甲酸酯形式。Metronidazole是一种合成的硝基咪唑衍生物，具有抗原生动物和抗细菌活性。
S4522	Dehydroacetic acid Dehydroacetic acid (Biocide 470F, Methylacetopyronone)是一种有机化合物，主要用作杀菌剂。
S4408	Procodazole Procodazole (Propazol, 2-Benzimidazolepropionic acid, 3-(1H-benzimidazole-2) propanoic acid)可用作增效剂，对病毒和细菌感染具有非特异性活性免疫保护作用。
S4565	Diiodohydroxyquinoline Diiodohydroxyquinoline (Iodoquinol) 是一种局部药物，喹啉衍生物，具有抗菌特性。
S5456	Isobavachalcone Isobavachalcone (Corylifolinin), a naturally occurring chalcone compound derived from the seeds of Psoralea corylifolia L., has long been used in traditional Chinese medicine as anthelmintic, antibacterial, aphrodisiac, astringent and antiplatelet agent.
S0906	6-Methoxydihydroavicine 6-Methoxydihydroavicine (6-Methoxy Dihydrosanguinarine) 是一种从是博落回果实中分离得到的生物碱。

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