CHIR-99021 (CT99021) HCl

目录号：S2924

Molecular Weight(MW): 501.8

CHIR-99021 (CT99021) HCl是CHIR-99021的盐酸盐, 是GSK-3α/β抑制剂，IC50为10 nM/6.7 nM。其对GSK-3的选择性比对Cdc2和ERK2高500倍以上。

规格

价格

库存

购买数量

10mM (in 1mL DMSO)	RMB 2780.99	现货
2mg	RMB 733.53	现货
5mg	RMB 1373.92	现货
25mg	RMB 4650.09	现货
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客户使用Selleck该产品发表文献73篇：

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Cell, 2018, 174(2):391-405

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Cell Stem Cell, 2015, 10.1016/j.stem.2015.04.020

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Circ Res, 2014, 115(6):556-66

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Nat Protoc, 2012, 8(1):162-75

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Nat Commun, 2015, 6:7413

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Nat Commun, 2013, 4:2628

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Proc Natl Acad Sci USA, 2014, 111(12):4484-9

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Proc Natl Acad Sci USA, 2012, 109(27):E1848-57

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Biomaterials, 2014, 35(5):1367-77

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Stem Cell Res, 2015, 10.1016/j.scr.2015.05.004

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Stem Cell Rep, 2014, 3(4):594-605

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Stem Cell Res, 2013, 12(2):364-375

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Stem Cell Rep, 2013, 1(4):360-10

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Antioxid Redox Sign, 2013, 20(18):2907-22

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Acta Biomater, 2014, 10(2):604-12

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Protein Cell, 2014, 5(1):59-68

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Biomater Sci, 2017, 5(8):1567-1578

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Stem Cells, 2015, 33(3):686-98

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Stem Cells, 2012, 30(9):1863-74

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Exp Mol Med, 2015, 47:e143

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Exp Mol Med, 2015, 47:e143

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Mol Cancer Ther, 2014, 13(4):812-22

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Mol Cancer Ther, 2013, 13(2):454-67

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Mol Cell Proteomics, 2014, 13(4):990-1007

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Mol Neurobiol, 2015, 10.1007/s12035-014-9084-z

PubMed: 25663198 ( click the link to review the publication )

Carcinogenesis, 2012, 33(3):529-37

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J Thromb Haemost, 2015, 10.1111/jth.12954

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Biochim Biophys Acta, 2013, 1830(8):4102-16

PubMed: 23628704 ( click the link to review the publication )

J Biol Chem, 2015, 290(9):5592-605

PubMed: ( click the link to review the publication )
J Biol Chem, 2014, 289(47):32628-38

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J Biol Chem, 2014, 10.1074/jbc.M114.580076

PubMed: 25301940 ( click the link to review the publication )

J Biol Chem, 2014, 289(20):14341-50

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J Biol Chem, 2013, 288(49):35500-10

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J Biol Chem, 2012, 287(2):893-904

PubMed: 22102280 ( click the link to review the publication )

Am J Cancer Res, 2014, 6(6):724-735

PubMed: ( click the link to review the publication )

Mol Pharmacol, 2014, 83(5):1020-9

PubMed: 23448715 ( click the link to review the publication )

Stem Cells Dev, 2015, 10.1089/scd.2014.0422

PubMed: 25751301 ( click the link to review the publication )

Stem Cells Dev, 2014, 23(14):1688-703

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Stem Cells Dev, 2014, 10.1089/scd.2014.0011

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Stem Cells Dev, 2014, 23(14):1688-703

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Exp Cell Res, 2014, 328(2):351-60

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Cell Transplant, 2015, 10.3727/096368914X685762

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PLoS One, 2016, 11(8):e0161508

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PLoS One, 2014, 9(12):e115854

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PLoS One, 2014, 9(1):e85089

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PLoS One, 2014, 9(4):e92304

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PLoS One, 2012, 7(10):e47312

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BMC Dev Biol, 2012, 12:21

PubMed: 22846383 ( click the link to review the publication )

Exp Biol Med, 2014, 239(10):1390-402

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Leuk Res, 2013, 37(10):1329-40

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Biol Open, 2015, 4(1):48-61

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Theriogenology, 2014, 82(2):283-93

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Cell Reprogram, 2014, 10.1089/cell.2014.0028

PubMed: 25084370 ( click the link to review the publication )
Exp Ther Med, 2016, 12(6):3851-3858

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J Huazhong Univ Sci Technolog Med Sci, 2014, 34(2):151-6

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Methods Mol Biol, 2016, 1353:181-90

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Methods Mol Biol, 2016, 1480:153-65

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J Physiol, 2015, 593(5):1147-57

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Sci Rep, 2015, 5:9718

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Methods Mol Biol, 2015, 10.1007/7651_2015_220

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Methods Mol Biol, 2015, 1264:453-63

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Cell Biology International Reports, 2015, 10.1002/cbi3.10019

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University of GOTHENBURG, 2014, 5495

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Sci Rep, 2014, 4:6425

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Methods Mol Biol, 2014, 10.1007/7651_2014_172

PubMed: 25520292 ( click the link to review the publication )
Bachelor of Science, 2012, East China Normal University

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客户使用该产品的9个实验数据：

Differentiation induced by treatment with the Gsk3 inhibitor in hPSCs is β-catenin dependent. H9-7TGP cells were treated with 12 uM CH in mTeSR1 for 4 d. Immunofluorescent staining for Oct4, Isl1, and Nkx2.5 was compared with GFP expression. (Scale bars, 50 uM.)

Proc Natl Acad Sci U S A 2012 109(27):E1848-57. CHIR-99021 (CT99021) HCl purchased from Selleck.

Gpc4 regulates ESC response to Wnt/β-catenin signaling. (E) Quantitative analysis of control and Gpc4-mutant beating foci exposed to the GSK3 inhibitor, CHIR 99021 (1 and 3 μM, from day 0 to day 5). Analysis was done at different time points. Gpc4- mutant cells treated with CHIR 99021 behave as controls (mean±SEM; n=2).

Stem Cells 2012 30, 1863-1874. CHIR-99021 (CT99021) HCl purchased from Selleck.
Characterization of rES cells. A: image of normal rES cell colonies on feeder layers. B: rES colonies were positive for AP staining. CeE: rES colonies readily expressed pluripotent markers, Sox2 (C), Oct4 (D), and SSEA-1 (E). Blue, DAPI. Scale bars: 100 um.

J Genet Genomics 2012 39, 643e651. CHIR-99021 (CT99021) HCl purchased from Selleck.

Inhibition of GSK3 activity induces an autophagic response in human pancreatic cancer cells. PANC1 cells were treated for 24 h with DMSO, CHIR99021 (CHIR; 5 uM) or the mTOR inhibitor Torin1 (250 nM). Autophagosome (punctate LC3B) (D) and lysosome (E) labeling was visualized with a Zeiss LSM700 confocal microscope. Images were acquired with a 20x (D) or 63x (E) objective. Nuclei were stained with DAPI. Scale bars, 20 祄.

J Biol Chem 2015 290(9), 5592-605 . CHIR-99021 (CT99021) HCl purchased from Selleck.
A. Vero cells were pretreated with the indicated concentrations of CHIR-99021 for 1 h and then infected with PEDV (MOI = 1) for 8 or 10 h. Cell lysates were prepared and analyzed using Western blotting.

PLoS One, 2016, 11(8):e0161508. CHIR-99021 (CT99021) HCl purchased from Selleck.

Smad linker phosphorylation involves GSK3 in human melanoma lines. Inhibition of Smad2 and Smad3 linker phosphorylation in the presence of the specific GSK3 specific inhibitor, CT99021. 24 hours post seeding, WM793 and 1205LU cells were serum-starved for about 16 hours, and incubated in the absence (2) or presence (+) of 2 uM of CT99021 for two hours. Immunoblots were performed as in A. p: Phosphorylated. S: Serine; T: Threonine.

PLoS One 2012 7, e47312. CHIR-99021 (CT99021) HCl purchased from Selleck.
SKOV3/DDP cells were treated with a range of concentration of (A) CHIR-99021 or in combination with 20 µM cisplatin for 48 h.

Exp Ther Med, 2016, 12(6):3851-3858. CHIR-99021 (CT99021) HCl purchased from Selleck.

PANC1 cells were treated with GSK3 inhibitors SB216763 (SB 10µM or SB 20µM) or CHIR99021 (CHIR 5µM) for 72h.

CHIR-99021 (CT99021) HCl purchased from Selleck.
Activity of canonical WNT/ β -CATENIN signals induced by CHIR 99021 in the developing human lung. Human lung tissue explants obtained at 15 weeks of gestation were exposed to 0, 5 and 10 μM CHIR 99021 in vitro for 72 h. (A-B) Western blot analysis showed expression of β -CATENIN in human lung tissues. Results are presented as the mean ± sem of three independent experiments. *P < 0.05, **P < 0.01. (C) qRT-PCR analysis detected a dose-dependent increase in WNT signaling transcription factors and target genes following exposure to CHIR 99021. Results are presented as the mean ± sem of three independent experiments. *P < 0.05, **P < 0.01. (D-K) Histology examination showed obvious morphogenetic changes of the airway epithelial cells associated with CHIR 99021 treated lung tubes. Scale bars: D-G =100 μm; H-K = 20 μm.

CHIR-99021 (CT99021) HCl purchased from Selleck.

产品安全说明书

GSK-3抑制剂选择性比较

生物活性

产品描述

CHIR-99021 (CT99021) HCl是CHIR-99021的盐酸盐, 是GSK-3α/β抑制剂，IC50为10 nM/6.7 nM。其对GSK-3的选择性比对Cdc2和ERK2高500倍以上。

靶点

GSK-3β ^[1] (Cell-free assay)	GSK-3α ^[1] (Cell-free assay)
6.7 nM	10 nM

体外研究

CHIR-99021作用于GSK-3比作用于其最接近的同系物CDC2和ERK2，及其他蛋白激酶选择性高500倍。此外，CHIR-99021只与一组22种药理相关的受体微弱结合，且对一组23种非激酶的酶几乎没有抑制活性。CHIR-99021作用于表达胰岛素受体的CHO-IR细胞，诱导糖原合成酶(GS)激活，EC50为0.763 μM。^[1]CHIR-99021(3 μM)作用于3T3-L1前脂肪细胞，除了模拟胰岛素的作用，抑制GSK-3，使胞内游离β-catenin增加1.9倍，模仿经典Wnt信号通路。在分化的前3天，CHIR-99021处理，抑制脂肪细胞分化，IC50为0.3 μM，通过抑制CCAAT/增强子结合蛋白α（C/EBPα）和过氧化物酶体增殖物激活受体γ（PPARγ）的诱导作用。^[2] 不像LiCl和AR-A014418，CHIR-99021处理，即使在高浓度，不会降低INS-1E细胞活力。相反，CHIR-99021增加INS-1E细胞增殖，这种作用具有剂量依赖性，且显著抑制高糖和高棕榈酸诱导的INS-E细胞死亡，这种作用具有浓度依赖性。CHIR-99021浓度低至1 μM，处理离体大鼠胰岛，促进β细胞复制，5 μM CHIR-99021处理，使细胞复制增长2-3倍。^[3]

Cell Data

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID
3T3-L1	MkLWSpVv[3Srb36gRZN{[Xl?	MkPjN{DPxE1?	NV7WWWpUPCCq	MVLEUXNQ	Mo\pTY5pcWKrdIOgdJJm[WSrcH;jfZRmKGSrZn\ldoVvfGmjdHnvci=>	MofWNVIxPTV{MEC=
insulin receptor–expressing CHO-IR	MnL3SpVv[3Srb36gRZN{[Xl?	M3;5N\|UxOCCwTR?=	Mn63N\|AhdWmw	MkD3SG1UVw>?	MWjBZ5RqfmG2ZYOgS4x6[2:pZX6gV5lvfGijc3WgLGdUMQ>?	MWOxNlYxPjR7Nx?=
H4IIE	M1z2bmZ2dmO2aX;uJGF{e2G7	NXTmNmhnOTBizszN	MlfrNlQhcA>?	NVLkdlFwTE2VTx?=	NWf5RoV7WmWpdXzheIV{KM7{LXPheIVvcW5iYXP0bZZqfHliYX7kJHRKWkViY3;ueIFqdmmwZzDwdo9ud3SncjDhZ5Rqfmm2eR?=	MVmxOVM2ODF7NR?=
Oct4/Sox2/Klf4-infected MEFs	MkLTSpVv[3Srb36gRZN{[Xl?	NYLxS2tQOTBizszN	MVGyPEBl	M{DTeGROW09?	MlHqVJJwdW:2ZYOgUWVHeyC{ZYDyc4dz[W2vaX7nJHRz[W6\|ZIXj[YQh[nliT3P0OEwhW2:6MjygZY5lKEuuZkS=	MYCxPVg{QTB3NR?=
Sca-1+ HPC	NGP3cIVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MWqyJO69VQ>?	M3nlNVYh\A>?	NHTo[YtFVVOR	M1LHVXN6dmW{Z3nzeIlk[WyueTDwdo9ud3SnczDTZ4EuOSwEoFjQR{Bxem:uaX\ldoF1cW:wIHHu[EBkd2yxbomg[o9zdWG2aX;uJJRw\2W2aHXyJJdqfGhiRVfG	NG[wfZUzOTZ{NEO0PC=>
HMC1.2	MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MY[zNEDPxE1?	NX;iTJIxPzJiaB?=	NH30d\|NFVVOR	MYLS[YR2[2W\|IHPlcIwhe3W{dnn2ZYw>	M1PFXlIzODN7M{Cx
Endothelial cell(EC)	M3vEWWZ2dmO2aX;uJGF{e2G7	NXznfVhGOyEQvF2=		NFv4dFdFVVOR	MUnQdo9ud3SnczDlcoRwfGinbHnhcEBk\WyuIDjFR{kh\GmoZnXy[Y51cWG2aX;u	NUfhfVJyOjJyNUKwNFY>
PANC1	M3XycWFxd3C2b4Ppd{BCe3OjeR?=	MUlCpFUh\|ryP	M2m0N\|czKGh?	NILDfpdFVVOR	NI\uS\|lVemmpZ3Xyd{BidiCjcH;weI91cWNicnXzdI9ve2V?	NIL0[HAzOjJyMUG4Oi=>
INS-1E	Mki2SpVv[3Srb36gRZN{[Xl?	MYOyMlUh\|ryP	M2XN[\|I1KGh?	MWnEUXNQ	M3zGWmlv\HWlZYOgZUBz\WS3Y4Tpc44hd2ZiTmCxJI93\XKneIDy[ZN{cW:w	M1vTNVIzPDJ5N{C0
hiPSC-NPs	MmH4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MmH4N-KBkc7:TR?=	M{j6NVczKGh?	NWX2TIk4TE2VTx?=	NUnCPZI2UW6lcnXhd4V{KGOnbHygdJJwdGmoZYLheIlwdsLi	NUDCZlN5OjJ4NEK2PFc>
platelets	M{fL[mZ2dmO2aX;uJGF{e2G7	NWXVNpJuOTBizszN	Mn;ONVUhdWmw	MoH4SG1UVw>?	NHLCSplKdmO{ZXHz[ZMhfGi{b33ibY4udWWmaXH0[YQheGyjdHXs[ZQh[WepcnXnZZRqd25iYX7kJGFVWCC\|ZXPy[ZRqd25?	NIK2TpgzOzJ\|OUi3Oy=>
DN3	NFXEN2lHfW6ldHnvckBCe3OjeR?=	NF3CfJQyOCEQvF2=	NVXYeG1GQTZiaB?=	MXXEUXNQ	M{T4PWlv[3KnYYPld{Bk\WyuIHTleoVtd3CvZX70JIFv\CCycn;sbYZmemG2aX;u	M1n0eFI{PTJ4OUi5
embryonic stem cells (ESC)	MV;GeY5kfGmxbjDBd5NigQ>?	M{TLWVMhyrWP	M1rpXlEyKGR?	MX7EUXNQ	MkTmVJJwdW:2ZYOgd4Vt\i2{ZX7le4FtKG:oIH7hx893\S22eYDlJI1wfXOnIHXtZpJ6d26rYzDzeIVuKGOnbHzzJEhGW0Nr	NXrWUYtYOjN6NEOzNVI>
H460	NGCzU29Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MnTZOUDDvU1?	NGPOVnUzPCCq	NEHoOndFVVOR	NHTpSpVRem:vb4Tld{Bk\WyuIIDyc4xq\mW{YYTpc44>	NIjOWVEzPDN4N{[4PC=>
H157	M1vCfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	NXLWemh6PSEEtV2=	MknLNlQhcA>?	MXPEUXNQ	MmHhVJJwdW:2ZYOgZ4VtdCCycn;sbYZmemG2aX;u	MXGyOFM3PzZ6OB?=
H460	NIrqXXFCeG:ydH;zbZMhSXO\|YYm=	M4CxSlUhyrWP	NWf5T3QyOjRiaB?=	NE\Ee2JFVVOR	M{PwVGF1fGWwdXH0[ZMh[2WubDDhdI9xfG:\|aYO=	NUfOU5UxOjR\|Nke2PFg>
H157	MWDBdI9xfG:\|aYOgRZN{[Xl?	NGDQ[FQ2KML3TR?=	NI\CO20zPCCq	M3HMeWROW09?	NHKwS5dFd2W\|IH7veEB{cWewaX\pZ4FvfGy7IHHm[oVkfCCjcH;weI9{cXN?	Ml;DNlQ{Pjd4OEi=
A549	NWLOcphPSXCxcITvd4l{KEG\|c3H5	NITBelI2KML3TR?=	MknnNlQhcA>?	MoW0SG1UVw>?	NUDxUI9pUW6lcnXhd4V{KGOnbHygZZBweHSxc3nz	MY[yOFM3PzZ6OB?=
Neural progenitor cells	NUfIfXl5TnWwY4Tpc44hSXO\|YYm=	NFvuc2M{KM7:TR?=	M4\ZNFExKGR?	MmrDSG1UVw>?	M3G0bWlv\HWlZYOg[4Vv\XKjdHnvckBw\iCwZYXyZYwheHKxZ3XubZRweiClZXzsdy=>	MVqyOFY{QDB\|NB?=
ES-D3	MUDDfZRwfG:6aXOgRZN{[Xl?	NVjrOng{OTEEoN88US=>	MWGzJIQ>	NX;WflZNTE2VTx?=	MnXyTY5lfWOnczDtc4RmemG2ZTDjfZRwfG:6aXPpeJkhf2m2aDDJR\|UxKG:oIESuPUDPxE1?	M3iycVI1Pzd7M{[1
ES-CCE	MorvR5l1d3SxeHnjJGF{e2G7	MlnSNVDDqM7:TR?=	NFHHdJU{KGR?	MofqSG1UVw>?	M2TPemlv\HWlZYOgcY9l\XKjdHWgZ5l1d3SxeHnjbZR6	M3fZVlI1Pzd7M{[1
ES-D3	MmmwSpVv[3Srb36gRZN{[Xl?	NWD2bFk1PcLizszN	NFLyToQ{KGR?	MYfEUXNQ	M2TsU3N1em:wZ3z5JIlv\HWlZYOgeIhmKGGldHn2bZR6KG:oIGfueE9j\XSjLXPheIVvcW5icHH0bJdigQ>?	MYKyOFc4QTN4NR?=
ES-CCE	MmP6SpVv[3Srb36gRZN{[Xl?	MnX4OeKh\|ryP	M3WzT\|Mh\A>?	MnLMSG1UVw>?	MoLmV5Rzd26pbImgbY5lfWOnczD0bIUh[WO2aY\peJkhd2ZiV370M4JmfGFvY3H0[Y5qdiCyYYToe4F6	NWjaWIpDOjR5N{mzOlU>
SW982	M1TFemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NEDtXGpKSzVyPUCuNlE1OTZizszN	MXLTRW5ITVJ?
GCT	NFX1eVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MUjJR\|UxRTBwM{C2O\|Ih\|ryP	MnW1V2FPT0WU
769-P	NEW2WYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MnT2TWM2OD1yLkW4OFk6KM7:TR?=	NE\OXXNUSU6JRWK=
LOXIMVI	M1\Wd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NGr6WVlKSzVyPUCuOVg5OzJizszN	MoDCV2FPT0WU
D-336MG	NEXsOHFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				Mn\BTWM2OD1yLki0OlIh\|ryP	Ml7VV2FPT0WU
S-117	M3ThdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NWL2bpBPUUN3ME2wMlkzOTNzIN88US=>	MWHTRW5ITVJ?
D-247MG	NIHjNpNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NYnn[HVKUUN3ME2wMlk1QDV{IN88US=>	NF60UVlUSU6JRWK=
TYK-nu	NVzvWXFiT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NI\TVZVKSzVyPUGuNFc6OTJizszN	NFr3V41USU6JRWK=
A498	MnXJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NEPEXYpKSzVyPUGuN\|A1PjlizszN	NYC4eXQ6W0GQR1XS
BCPAP	M3m4cmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M4DYO2lEPTB;MT62Olg6QCEQvF2=	NH7heY1USU6JRWK=
KYSE-180	M1fMU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NXi5dZd6UUN3ME2xMlczPzh6IN88US=>	MV3TRW5ITVJ?
MIA-PaCa-2	Ml:zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NYLjUYlvUUN3ME2xMlc2QTd5IN88US=>	MWrTRW5ITVJ?
HCC1395	MnfMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MmmwTWM2OD1zLke4Nlc{KM7:TR?=	MorYV2FPT0WU
RS4-11	NW\aWnVOT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MWnJR\|UxRTFwOUW0NVUh\|ryP	MVrTRW5ITVJ?
NCI-H2122	NFjlcJFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NIjNdYhKSzVyPUKuNlc3QDRizszN	Mo\SV2FPT0WU
SNU-423	M2\wZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M2O2WmlEPTB;Mj60PVc5PyEQvF2=	NWP6ZpplW0GQR1XS
SK-LMS-1	MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M{XnRWlEPTB;Mj62OFEzQCEQvF2=	MWTTRW5ITVJ?
RPMI-7951	NUPSNHNHT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NGG5RYJKSzVyPUKuO\|AyQTNizszN	MYrTRW5ITVJ?
COLO-829	NEnaZlBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MYfJR\|UxRTJwN{[1OEDPxE1?	MUnTRW5ITVJ?
SCC-9	NIryNFVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NUjlVZdmUUN3ME2yMlk2PDh3IN88US=>	NY\FRphmW0GQR1XS
A704	NEf5W3RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NWPpPYtVUUN3ME2zMlA5OTJizszN	MkHWV2FPT0WU
HOP-62	NUSzOFZpT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NX:5dHpQUUN3ME2zMlM3ODV2IN88US=>	NYPXeFFNW0GQR1XS
HCC1569	MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NHn6OYFKSzVyPUOuOFg{ODVizszN	NWPLXlBPW0GQR1XS
A172	NHjsSHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MUTJR\|UxRTNwN{W0PVgh\|ryP	NIfHS\|BUSU6JRWK=
MOLT-16	M3zUcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MYXJR\|UxRTNwOEi1OVYh\|ryP	MkXqV2FPT0WU
TE-15	NEPRSJdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NY\IZZJ4UUN3ME2zMlk2OzR\|IN88US=>	MVTTRW5ITVJ?
OE19	MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MWXJR\|UxRTNwOU[0OVEh\|ryP	MXTTRW5ITVJ?
MHH-ES-1	NHTz[VNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M1XmdGlEPTB;ND6wOFU1PSEQvF2=	MmrLV2FPT0WU
NKM-1	M3Pzcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NFvw[nhKSzVyPUSuNVM6PzFizszN	NVfxVIhtW0GQR1XS
RCC10RGB	M4LoT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M{nvZWlEPTB;ND6yPVQ4QSEQvF2=	NUntbGRGW0GQR1XS
BxPC-3	NVnIXY1VT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				Mnq2TWM2OD12LkewN\|kyKM7:TR?=	MmG3V2FPT0WU
ALL-PO	MnrIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MkPITWM2OD12LkizPFU5KM7:TR?=	NHe4b49USU6JRWK=
SK-OV-3	NEnxdm1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NGHWc\|hKSzVyPUSuPVk{PCEQvF2=	M4nMZ3NCVkeHUh?=
SW1710	NWrRdFFkT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MnHmTWM2OD13LkSyOFU3KM7:TR?=	MojkV2FPT0WU
NCI-H2452	MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MY\JR\|UxRTVwNEW2Nlgh\|ryP	MULTRW5ITVJ?
D-392MG	Mn[xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NELTcldKSzVyPUWuOFkyPDVizszN	NYrGUnFmW0GQR1XS
LB2518-MEL	NU\MZ5FUT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MmLGTWM2OD13LkeyOlI4KM7:TR?=	NV7MfZZUW0GQR1XS
BL-41	NFv5SYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MVXJR\|UxRTVwOEGyOlYh\|ryP	NFrqb3pUSU6JRWK=
WM-115	MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M33qWGlEPTB;NT64NVUxQSEQvF2=	NEn2[opUSU6JRWK=
SK-MEL-2	NXjYVWtbT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MoPJTWM2OD14LkO4N\|Q1KM7:TR?=	NXr5doxTW0GQR1XS
CGTH-W-1	MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NVm4ZnVWUUN3ME22MlQyPyEQvF2=	MYDTRW5ITVJ?
BB65-RCC	NEfTNpNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M1PhbGlEPTB;Nj61N\|E6PSEQvF2=	Mm[5V2FPT0WU
CAL-85-1	MkXqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NX;jXJZ6UUN3ME22MlYxQTN4IN88US=>	M4HpS3NCVkeHUh?=
RT-112	M4nBU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NXHZS5k4UUN3ME23MlE3PDV4IN88US=>	MWHTRW5ITVJ?
MC116	NWnMN2I5T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NVy0eodoUUN3ME23MlI5PjlzIN88US=>	NYjrbHMxW0GQR1XS
G-361	MlLxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NWK4e\|dVUUN3ME23MlQ3PTZzIN88US=>	MnT6V2FPT0WU
SW1417	MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MkXiTWM2OD15Lk[0OVg1KM7:TR?=	NY\NWYl1W0GQR1XS
MV-4-11	NWf2WHMxT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M1zwSWlEPTB;OD61OFMxPCEQvF2=	M3XFT3NCVkeHUh?=
CAL-72	MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NGnNToJKSzVyPUiuO\|YyOTNizszN	NUKyV2hoW0GQR1XS
MKN28	NHXsW4JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MVfJR\|UxRThwOEi1NVYh\|ryP	MkXBV2FPT0WU
MEG-01	M{Tjemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NHXzcmNKSzVyPUiuPVkxPDNizszN	M2r2fXNCVkeHUh?=
ACHN	NXnWTYxlT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MojWTWM2OD17LkOwOVQ3KM7:TR?=	NIDYeJVUSU6JRWK=
NCI-H1755	MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				Mm\oTWM2OD17LkO5PVg3KM7:TR?=	NEi3SlNUSU6JRWK=
NCI-H64	NH\ye\|hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NVfq[FB6UUN3ME25MlQzOjV3IN88US=>	NUWz[nlvW0GQR1XS
COLO-205	MlH3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MVrJR\|UxRTlwNEO4NlEh\|ryP	M2Ph[3NCVkeHUh?=
CTV-1	MmTLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NFyxWphKSzVyPUmuOFM5QTRizszN	MVjTRW5ITVJ?
U-2-OS	MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NXOwfoZlUUN3ME25MlQ2ODB4IN88US=>	NIrXeHJUSU6JRWK=
LB996-RCC	NETrOodIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NFPMWHdKSzVyPUmuOVI{QTdizszN	NXz4U4JzW0GQR1XS
SK-N-DZ	NVHRUIxnT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MoOxTWM2OD17Lk[1O\|QzKM7:TR?=	Mn;MV2FPT0WU
EFM-19	M3HHUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M1rRNmlEPTB;OT63OVU3PiEQvF2=	MnnDV2FPT0WU
DBTRG-05MG	NFHC[WVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MYDJR\|UxRTlwN{e3O{DPxE1?	NUjpbpptW0GQR1XS
U-118-MG	M1fUOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MWTJR\|UxRTlwOUS0OFQh\|ryP	NF\DSpVUSU6JRWK=
LB1047-RCC	NGjpTFFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NGP5ZWVKSzVyPUmuPVk4QThizszN	NVzQTnc6W0GQR1XS
NCI-H28	M3r3RWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NXXXbohKUUN3ME2xNE41PDF\|IN88US=>	NViyNXhtW0GQR1XS
MZ2-MEL	NHPtVYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MlvyTWM2OD1zMD60Olc4KM7:TR?=	NF\HOo5USU6JRWK=
M059J	Ml\4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M2T0U2lEPTB;MUCuOlExOiEQvF2=	NV;CWW5nW0GQR1XS
HT-3	MlXpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MXPJR\|UxRTFyLk[xO\|kh\|ryP	MmPYV2FPT0WU
SNU-387	NHX6UodIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NELIPJBKSzVyPUGwMlczOzVizszN	M3O0NXNCVkeHUh?=
NCI-H526	MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NETtUFlKSzVyPUGxMlE{PjVizszN	MkLsV2FPT0WU
HEL	MnKyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NGfwdppKSzVyPUGxMlY2PzlizszN	MmPBV2FPT0WU
PA-1	M1;acWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MXzJR\|UxRTFzLkmzJO69VQ>?	M2fQbXNCVkeHUh?=
PC-14	MkXiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NHfsfFJKSzVyPUGyMlMzPCEQvF2=	NHrmfYhUSU6JRWK=
C8166	Ml;nS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NHvIR3dKSzVyPUGzMlI{OThizszN	NUPGVnlnW0GQR1XS
NCI-H82	MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M2HXN2lEPTB;MUOuNlkxQSEQvF2=	M4TZN3NCVkeHUh?=
DSH1	NHqwUo9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M3zYZWlEPTB;MUOuN\|g4QSEQvF2=	MYfTRW5ITVJ?
T98G	Ml\LS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Mk\ETWM2OD1zMz60O\|E4KM7:TR?=	NXvReHM3W0GQR1XS
KU812	NUDweWdlT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NFPpXWdKSzVyPUGzMlUyPzVizszN	Ml3kV2FPT0WU
SW48	NX:4R3NiT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M1OzOGlEPTB;MUOuO\|I3PSEQvF2=	NUfqTld{W0GQR1XS
MEL-HO	MmHIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M{XFbWlEPTB;MUOuPFgzQSEQvF2=	NHrTUIFUSU6JRWK=
SF539	NVPSb5lpT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MW\JR\|UxRTF2LkCxNVYh\|ryP	NFm5eWlUSU6JRWK=
NB1	MornS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M4fJRmlEPTB;MUSuNVk{PSEQvF2=	M3zTZ3NCVkeHUh?=
ST486	MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M3;JW2lEPTB;MUSuNlI2OSEQvF2=	MUfTRW5ITVJ?
LoVo	NF3HVYhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NIXWPVhKSzVyPUG1MlI3PTlizszN	MV7TRW5ITVJ?
NH-12	NF7QXZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M4rN[2lEPTB;MU[uNFA6PyEQvF2=	MYLTRW5ITVJ?
CCRF-CEM	MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				Mon0TWM2OD1zNj62O\|AzKM7:TR?=	NHvHTlhUSU6JRWK=
Daudi	MmjZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MVfJR\|UxRTF5Lk[xOFkh\|ryP	NYnCd5U{W0GQR1XS
SIMA	NGi1SYxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MXTJR\|UxRTF5LkmxNVgh\|ryP	MX\TRW5ITVJ?
8305C	NVO1SXRuT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MYTJR\|UxRTF6LkWzNFUh\|ryP	NWOyfIpFW0GQR1XS
EM-2	MlPGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M3njNWlEPTB;MUiuOlI1QCEQvF2=	M4XwZ3NCVkeHUh?=
SNU-449	M3PPXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MXTJR\|UxRTF6LkexOUDPxE1?	MYTTRW5ITVJ?
A101D	MmPRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NYPUfmR7UUN3ME2xPU4zPDNizszN	MVzTRW5ITVJ?
MHH-NB-11	M360cGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NEDTe2xKSzVyPUG5MlU{PDJizszN	MnrCV2FPT0WU
Becker	NVK1VWFVT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MUjJR\|UxRTJyLkG3O\|ch\|ryP	M2P4S3NCVkeHUh?=
NCI-H727	M{PvfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NH\0UJNKSzVyPUKwMlIyPjlizszN	M2TsbHNCVkeHUh?=
HCC1187	NYnUUooxT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NYrZUVB2UUN3ME2yNE4{PTh7IN88US=>	MlzuV2FPT0WU
KYSE-450	NGfrbYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				Ml63TWM2OD1{MT61N\|U1KM7:TR?=	Mn\MV2FPT0WU
SK-MEL-28	NH\sO2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MY\JR\|UxRTJzLk[4OlMh\|ryP	MlPLV2FPT0WU
BPH-1	M3fZ[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NWD1fmFmUUN3ME2yNU44ODN3IN88US=>	M{\xUnNCVkeHUh?=
EoL-1-	NFjyTJJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MWLJR\|UxRTJzLkizPFUh\|ryP	MorNV2FPT0WU
TGBC24TKB	MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M1TqdGlEPTB;MkGuPFk2PyEQvF2=	NYXvUFg{W0GQR1XS
KARPAS-299	MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MkLtTWM2OD1{Mj6xPVU1KM7:TR?=	MW\TRW5ITVJ?
SW684	M4LqNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M{\B[mlEPTB;MkKuNlg2QCEQvF2=	NHHKc4lUSU6JRWK=
RXF393	NESwTmZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NE\afWtKSzVyPUKyMlYxPjhizszN	M4jEXnNCVkeHUh?=
LS-513	NWHBXos{T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MVzJR\|UxRTJ{Lk[xPVIh\|ryP	Mn34V2FPT0WU
KURAMOCHI	MlTGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MmnwTWM2OD1{Mj63NFY6KM7:TR?=	MlL3V2FPT0WU
GI-1	M4LYOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NGPKU3ZKSzVyPUKyMlc5PDFizszN	MXfTRW5ITVJ?
M14	NUfNd29lT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NFjGXHpKSzVyPUKzMlEyOzJizszN	NYOwVZJrW0GQR1XS
REH	M2\Uc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NFe4cHdKSzVyPUKzMlE3QTlizszN	NUnpVoJ7W0GQR1XS
K5	MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M3LveWlEPTB;MkOuOVQ5PiEQvF2=	Mli2V2FPT0WU
PANC-10-05	MkG3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MUXJR\|UxRTJ2LkC4PVgh\|ryP	NFf3UVNUSU6JRWK=
HMV-II	M2n0[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M1fNTGlEPTB;MkSuNlE3OyEQvF2=	NUDyd5Q4W0GQR1XS
NCI-H1963	NIS3XnJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				Mlq0TWM2OD1{ND6yPFM6KM7:TR?=	NGi1flNUSU6JRWK=
LU-139	MlXSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NH\rPGxKSzVyPUK0Mlg{PSEQvF2=	MV3TRW5ITVJ?
KASUMI-1	MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MXLJR\|UxRTJ2LkmzNlgh\|ryP	MoqxV2FPT0WU
RO82-W-1	MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M{HWW2lEPTB;Mk[uO\|M4PyEQvF2=	MlLKV2FPT0WU
NCI-H1770	MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M3;PVmlEPTB;Mk[uPFk5PiEQvF2=	NHzw[mFUSU6JRWK=
SNG-M	MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M4T2N2lEPTB;MkeuNlI4OSEQvF2=	M1nGXnNCVkeHUh?=
KLE	MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MYrJR\|UxRTJ5LkK1OlUh\|ryP	M1HCUHNCVkeHUh?=
NCI-H2170	NX\pTI9yT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NEPYXXdKSzVyPUK3MlUzQDJizszN	NXrJO5JnW0GQR1XS
COLO-792	NWnPZ4lsT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				Mn:4TWM2OD1{Nz63O\|I5KM7:TR?=	Mo\MV2FPT0WU
ES8	M1zlUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NYLub4tLUUN3ME2yO{44QDF2IN88US=>	MXrTRW5ITVJ?
MC-CAR	M{fzTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NWrLTXZiUUN3ME2yO{44QTB5IN88US=>	Mm[4V2FPT0WU
SU-DHL-1	M1\1W2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M2XWeWlEPTB;MkeuPVQ4PCEQvF2=	M1jaWnNCVkeHUh?=
OAW-28	MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				Ml2yTWM2OD1{OD6wNFUzKM7:TR?=	MVLTRW5ITVJ?
C32	MojUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MnjkTWM2OD1{OD6wPFI3KM7:TR?=	NUDOcVV5W0GQR1XS
SW872	M3;1Omdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MVfJR\|UxRTJ6LkWzNlYh\|ryP	MlXiV2FPT0WU
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LCLC-103H	MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NH\6T4dKSzVyPUOwMlIxPTlizszN	MX3TRW5ITVJ?
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LCLC-97TM1	NHLqc2NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MWXJR\|UxRTV7LkC1OVMh\|ryP	M4C4R3NCVkeHUh?=
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BOKU	NHqzUndIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M{LvOmlEPTB;OUKuOlk2PyEQvF2=	M13SPHNCVkeHUh?=
CAL-33	MlHqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M3Xa[2lEPTB;OUOuNFYxOSEQvF2=	NILCbY1USU6JRWK=
23132-87	NXe5WmFwT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MUXJR\|UxRTl\|LkG2PEDPxE1?	MXvTRW5ITVJ?
J82	M4HTNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M3;MWmlEPTB;OUOuO\|gyOSEQvF2=	M1PuPHNCVkeHUh?=
MZ1-PC	M4jB[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M4HaSWlEPTB;OUSuOVk5PCEQvF2=	MX\TRW5ITVJ?
MEL-JUSO	MnrzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Mkn1TWM2OD17ND65OVQh\|ryP	MWXTRW5ITVJ?
RMG-I	M{TRfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M4PUZWlEPTB;OUWuNVA4OiEQvF2=	NYnjS5hNW0GQR1XS
A2058	M3vWS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M3fFTmlEPTB;OUWuOFYyPyEQvF2=	M33YeXNCVkeHUh?=
Caov-4	NFHvSGhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MmXBTWM2OD17NT62PFUh\|ryP	NGGyRYxUSU6JRWK=
OS-RC-2	M{WzV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NVPHd29DUUN3ME25O{41PjFizszN	MVfTRW5ITVJ?
MKN7	Mm\LS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NFrKdZNKSzVyPUm3Mlc1OzlizszN	MWfTRW5ITVJ?
U-698-M	NISwfYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NI[w[ZhKSzVyPUm4Mlk1QDlizszN	NUPnWIdJW0GQR1XS
PC-3	MmLOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M3jZXGlEPTB;OUmuNFU3PCEQvF2=	NYXuVY01W0GQR1XS
NCI-H292	MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MlvOTWM2OD17OT6zNFA1KM7:TR?=	M17acXNCVkeHUh?=
IGR-1	M4TxUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NInWRWJKSzVyPUm5MlMyOTlizszN	NYTDfm1VW0GQR1XS
Mewo	NF\GcXJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MX3JR\|UxRTl7LkW2NFMh\|ryP	Ml35V2FPT0WU
LU-65	MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NWr3[\|RyUUN3ME2xNFEvODhzIN88US=>	M{SySHNCVkeHUh?=
Saos-2	MnewS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NIX2VWlKSzVyPUGwNU41OzdizszN	MULTRW5ITVJ?
TE-11	MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NImwPYhKSzVyPUGwNU44OjRizszN	NVLEc2c1W0GQR1XS
SK-MES-1	NYruV5VZT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NVftd29UUUN3ME2xNFEvPzZ{IN88US=>	MkPTV2FPT0WU
KE-37	NGnlR3ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NIrJcItKSzVyPUGwNk46PSEQvF2=	NUnTdlZTW0GQR1XS
MKN45	M4XKc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M2XsZmlEPTB;MUCzMlU5PCEQvF2=	NVjpNGhqW0GQR1XS
UM-UC-3	M2TCUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NGHjWm1KSzVyPUGwN{45PDJizszN	MnTIV2FPT0WU
SNU-C2B	NYLJTXd1T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MVvJR\|UxRTFyNT6wNlMh\|ryP	M2\aXnNCVkeHUh?=
RPMI-8226	MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NITXWVJKSzVyPUGwOk43PzhizszN	M4S2[HNCVkeHUh?=
PANC-08-13	NXPhfpVFT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MUTJR\|UxRTFyNj64OUDPxE1?	NYTafHRDW0GQR1XS
NCI-H23	M3:3SWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M3uxTGlEPTB;MUC4MlM2PyEQvF2=	MXzTRW5ITVJ?
HOP-92	MlS4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NFm2eHhKSzVyPUGwPE41PzVizszN	M1fDUXNCVkeHUh?=
FTC-133	Moq5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MojWTWM2OD1zMEiuOFg5KM7:TR?=	NITaS2xUSU6JRWK=
D-263MG	NUO5PHJnT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NWTTTIMxUUN3ME2xNFgvQTZzIN88US=>	M4LVeHNCVkeHUh?=
DU-145	M{\Kemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MWTJR\|UxRTFyOT65OFUh\|ryP	NXvJbJFbW0GQR1XS
A253	NX7U[HhKT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MYLJR\|UxRTFzMD60O\|kh\|ryP	MmPMV2FPT0WU
HCT-15	M2Tzdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M2L2cWlEPTB;MUGwMlY3OSEQvF2=	MYHTRW5ITVJ?
WSU-NHL	NHvtbHJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NVnZW2U2UUN3ME2xNVIvODFizszN	M3m0enNCVkeHUh?=
U031	NVHjVIlMT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MUfJR\|UxRTFzMj6wOlUh\|ryP	M2PN[3NCVkeHUh?=
MDA-MB-157	NYn3TmR3T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MkXzTWM2OD1zMUKuOFkh\|ryP	MWHTRW5ITVJ?
NEC8	MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NWnVNVJ3UUN3ME2xNVIvPjJ2IN88US=>	MULTRW5ITVJ?
SIG-M5	NIfmdIVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				Mn\xTWM2OD1zMUOuNVI2KM7:TR?=	NF;HfmJUSU6JRWK=
786-0	MmH6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M4PKVmlEPTB;MUGzMlQ2OyEQvF2=	NGD4d3dUSU6JRWK=
DMS-273	NGq2eIFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M{DaTWlEPTB;MUG1MlYyPyEQvF2=	NICxemFUSU6JRWK=
Calu-6	M4fIRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M{OxfWlEPTB;MUG2Mlc6QCEQvF2=	NVOz[ZhzW0GQR1XS
HCC1599	NFLyZXFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MX;JR\|UxRTFzNz6xOVYh\|ryP	Mn24V2FPT0WU
OVCAR-8	MoXSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NXfwfmI5UUN3ME2xNVcvPjZ6IN88US=>	NI[x[XlUSU6JRWK=
ATN-1	NVexeWVNT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MV3JR\|UxRTFzNz64Nlgh\|ryP	NFHWZ2ZUSU6JRWK=
RKO	MonFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M1q5eGlEPTB;MUG3Mlg6QCEQvF2=	Mk[yV2FPT0WU
SKG-IIIa	NV7oSpV1T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M4C0d2lEPTB;MUG4MlEyPiEQvF2=	NHjNVG9USU6JRWK=
SUP-T1	MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NGraNpVKSzVyPUGxPE46PTZizszN	Mm\iV2FPT0WU
KNS-81-FD	NITzOZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M1PhPGlEPTB;MUG5MlQyPyEQvF2=	NEfSR3RUSU6JRWK=
OVCAR-3	MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MYjJR\|UxRTFzOT65NVUh\|ryP	NInXOmZUSU6JRWK=
NCI-N87	NFfqXopIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M1vvTmlEPTB;MUKxMlA1PCEQvF2=	MlHhV2FPT0WU
HuP-T4	NFfTNW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NW\xbZo3UUN3ME2xNlEvPTVizszN	M1zkW3NCVkeHUh?=
KYSE-140	NVPKfox6T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NG\jT3BKSzVyPUGyNk4yPDFizszN	MU\TRW5ITVJ?
HAL-01	NFS1d4pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MVTJR\|UxRTF{Mj60PVkh\|ryP	NH2xbY9USU6JRWK=
HT-29	MnK0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MnW2TWM2OD1zMkKuO\|c5KM7:TR?=	MlnwV2FPT0WU
OPM-2	MmLsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MW\JR\|UxRTF{Mz6xO\|Yh\|ryP	NF;IdFRUSU6JRWK=
SW1463	MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MoDiTWM2OD1zMkSuNFc4KM7:TR?=	NYrFR4I2W0GQR1XS
NCI-H2087	MnW3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NG\mU3FKSzVyPUGyOE4zQDNizszN	M2DCPXNCVkeHUh?=
UMC-11	NFXnRXBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M1zwdGlEPTB;MUK2MlA{QCEQvF2=	M2WzUHNCVkeHUh?=
EB-3	MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M1no[mlEPTB;MUK3MlAyOyEQvF2=	NIHvUY5USU6JRWK=
HEC-1	Mme1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NXvXOXFkUUN3ME2xNlkvOTl6IN88US=>	MVjTRW5ITVJ?
LU-99A	MlzVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M3zZV2lEPTB;MUK5Mlk{OSEQvF2=	M3rWdXNCVkeHUh?=
VMRC-RCZ	MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MWrJR\|UxRTF\|MD6zO\|Uh\|ryP	M{noWnNCVkeHUh?=
MFH-ino	Mnq1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NYTOeGoyUUN3ME2xN\|EvOTF2IN88US=>	M1Xad3NCVkeHUh?=
HT-1080	MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NU\QbVJyUUN3ME2xN\|IvOjB2IN88US=>	NUj6TpJGW0GQR1XS
CTB-1	M2i2UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MYDJR\|UxRTF\|Mj64PVch\|ryP	NIqz[nBUSU6JRWK=
Capan-2	MnyxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M1HkPWlEPTB;MUOzMlk4PSEQvF2=	M{PQ[3NCVkeHUh?=
BB30-HNC	NF;HbldIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MXvJR\|UxRTF\|ND6xNVYh\|ryP	MX7TRW5ITVJ?
CP50-MEL-B	NHKyWGJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MnnETWM2OD1zM{SuNkDPxE1?	Mo\MV2FPT0WU
JEG-3	Mmq0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NVjyco1UUUN3ME2xN\|QvOzV7IN88US=>	NXX5cpV1W0GQR1XS
NCI-H1437	NUflS3ZFT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M1nQTmlEPTB;MUO0MlU6KM7:TR?=	NEPmXY1USU6JRWK=
NOS-1	NVPtNlYzT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MXLJR\|UxRTF\|ND63OlUh\|ryP	NHXBeXFUSU6JRWK=
G-402	M4rNV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				Ml\ETWM2OD1zM{WuNlk2KM7:TR?=	MmrsV2FPT0WU
OAW-42	NGLxcohIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NFLlS\|RKSzVyPUGzO{45PTZizszN	NYXrWJJrW0GQR1XS
Ca-Ski	NVm2WINQT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NYjTPVlCUUN3ME2xN\|gvQDNzIN88US=>	M3\M[nNCVkeHUh?=
BHT-101	NI\DR\|VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NHfC[ndKSzVyPUG0NE4zODhizszN	NFnQcmdUSU6JRWK=
OVCAR-4	MlSwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MkfpTWM2OD1zNECuO\|Q6KM7:TR?=	MlnyV2FPT0WU
Detroit562	NU\XfIFTT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NWDGU2trUUN3ME2xOFEvPDZ4IN88US=>	Mn;iV2FPT0WU
OCI-AML2	M1z2fGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MXPJR\|UxRTF2MT61NFch\|ryP	M4XGfHNCVkeHUh?=
OE33	NYOwPHBYT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				Mni4TWM2OD1zNEGuO\|k5KM7:TR?=	M2PwdHNCVkeHUh?=
YKG-1	MoO0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MlezTWM2OD1zNEKuPFg6KM7:TR?=	MlfRV2FPT0WU
CCF-STTG1	NYPUXZFRT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NWXtRlBWUUN3ME2xOFMvOzN2IN88US=>	NHPHcYlUSU6JRWK=
NCI-H810	Mn65S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MV7JR\|UxRTF2Mz62PFch\|ryP	NVX6T\|IxW0GQR1XS
SCC-25	NWHUW2tyT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NVnQXotEUUN3ME2xOFQvODB3IN88US=>	MlTQV2FPT0WU
HTC-C3	NIfvXVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MlywTWM2OD1zNEWuNFc2KM7:TR?=	NHXZU3FUSU6JRWK=
G-401	NWTPZVlyT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M2DRZmlEPTB;MUS1Mlg{PSEQvF2=	Mnm3V2FPT0WU
OMC-1	Ml3FS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NFzI[mJKSzVyPUG0OU46PjdizszN	NHH0W4xUSU6JRWK=
LK-2	NFrzVWtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M2n1TWlEPTB;MUS3MlE1OyEQvF2=	MoXqV2FPT0WU
SW13	MkfjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M4PaXGlEPTB;MUS3MlI2OyEQvF2=	M1qx[XNCVkeHUh?=
BB49-HNC	Mm[wS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Mmj4TWM2OD1zNEeuOFA1KM7:TR?=	NUDoTWV7W0GQR1XS
DMS-114	NUm5TJdmT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MYHJR\|UxRTF2Nz60OFEh\|ryP	MmrCV2FPT0WU
GCIY	Mmj3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M1vKNGlEPTB;MUS3Mlc6PyEQvF2=	MmHJV2FPT0WU
GAMG	M{W4e2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NX7WemN1UUN3ME2xOFgvOjR5IN88US=>	NVTjNZU6W0GQR1XS
KYSE-520	NUPtTo86T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NUHuZnpRUUN3ME2xOFgvPTRizszN	M{PHPXNCVkeHUh?=
LB647-SCLC	MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NULDToZOUUN3ME2xOFgvPTZ{IN88US=>	NEXIWVJUSU6JRWK=
639-V	NVLYcWJkT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NF31TFVKSzVyPUG0PE44ODVizszN	MorDV2FPT0WU
TE-9	M{jLcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NHHBXoFKSzVyPUG0PU41PDNizszN	MYHTRW5ITVJ?
Caov-3	MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MW\JR\|UxRTF2OT63NVQh\|ryP	NYjHOGRSW0GQR1XS
L-540	NGj5[G1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M2fhe2lEPTB;MUS5Mlc2KM7:TR?=	M2C2R3NCVkeHUh?=
NCI-H748	NWj3bFk5T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NHLwTlVKSzVyPUG1NE4zODlizszN	M1XTPXNCVkeHUh?=
GDM-1	NUK2fWRUT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NXvjOmNJUUN3ME2xOVEvOTN3IN88US=>	NWXWVGpLW0GQR1XS
GAK	M3\lTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M2npe2lEPTB;MUWxMlM4PCEQvF2=	MofsV2FPT0WU
AsPC-1	NVHJZpFyT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M3iwR2lEPTB;MUWyMlc3PCEQvF2=	NIXOUoFUSU6JRWK=
MDA-MB-361	NUPySJdvT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NFXVZlFKSzVyPUG1N{4yPjRizszN	NFL5V\|JUSU6JRWK=
TT	M4XDemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M{O4RmlEPTB;MUWzMlQ6KM7:TR?=	NHLBc2VUSU6JRWK=
Calu-1	NYDKRoFoT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M2DlZWlEPTB;MUW0MlAxOyEQvF2=	NH\4OYdUSU6JRWK=
RERF-LC-MS	M3HpVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MYHJR\|UxRTF3ND63O\|Ih\|ryP	NY\SSZRtW0GQR1XS
DK-MG	NH;w[4hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M1nYdWlEPTB;MUW1MlE5OyEQvF2=	MXLTRW5ITVJ?
CAL-120	NGTLNY1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NVnFR4tQUUN3ME2xOVUvQDJzIN88US=>	MnyxV2FPT0WU
HCC1419	NUTL[3J6T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M2Tze2lEPTB;MUW2MlA4PyEQvF2=	NFzFZZdUSU6JRWK=
DG-75	NXrQOYRYT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MU\JR\|UxRTF3Nj62PVQh\|ryP	MV3TRW5ITVJ?
HCC38	NVGxco5OT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NUXRRWg{UUN3ME2xOVcvOzZ7IN88US=>	NHnP[2JUSU6JRWK=
HCC70	MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MmfPTWM2OD1zNUmuNlQzKM7:TR?=	M1m4dHNCVkeHUh?=
ES4	NGnUO5RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M1v3WWlEPTB;MUW5MlM6PiEQvF2=	NV\NOok1W0GQR1XS
NCI-H2052	MnriS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M1PQOWlEPTB;MUW5MlU5OyEQvF2=	NF65[4RUSU6JRWK=
EFO-27	M1:xcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NX\N[4kzUUN3ME2xOlAvPTh2IN88US=>	NXm5eGdtW0GQR1XS
CAL-62	NIj2bldIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MkDtTWM2OD1zNkKuOlE{KM7:TR?=	NXLQe5RCW0GQR1XS
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DJM-1	M375bGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NVrs[mw{UUN3ME2yNFkvQDl5IN88US=>	MnLMV2FPT0WU
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NCI-H1618	NWmyXXUzT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MlTSTWM2OD1{MkGuNFE5KM7:TR?=	M2HTUHNCVkeHUh?=
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IPC-298	MmDJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Mnr3TWM2OD1{NEKuNFczKM7:TR?=	MVLTRW5ITVJ?
GP5d	NWnubJFKT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MXvJR\|UxRTJ2Mj62NVYh\|ryP	M4LkT3NCVkeHUh?=
HN	MnS3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MmrmTWM2OD1{NEKuPVkyKM7:TR?=	NVPhS5NxW0GQR1XS
BFTC-909	NWnXNXl3T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M1;sXGlEPTB;MkSzMlEyQCEQvF2=	M1rxenNCVkeHUh?=
ES5	NGPY[GJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NXi3T2FTUUN3ME2yOFUvODN6IN88US=>	M3HUZ3NCVkeHUh?=
SK-HEP-1	NEjtd4dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M{fDS2lEPTB;MkS2MlA1OyEQvF2=	NV3CVY1oW0GQR1XS
T47D	MofrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NX\EdGxMUUN3ME2yOFcvODF\|IN88US=>	M3r1eXNCVkeHUh?=
KYSE-510	NGLFPVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MYnJR\|UxRTJ2Nz61NVch\|ryP	M4HkNHNCVkeHUh?=
LC-1F	M1TqTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NYDNWm9PUUN3ME2yOFgvOTV4IN88US=>	Mm\6V2FPT0WU
NCI-H1693	MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				Mn7ETWM2OD1{NEmuOFk2KM7:TR?=	NYOweXVKW0GQR1XS
COR-L23	MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MXLJR\|UxRTJ3MD60NVIh\|ryP	NWTYVHBkW0GQR1XS
NCI-H2228	MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M{fp[GlEPTB;MkWwMlg3PCEQvF2=	NHPjdlVUSU6JRWK=
NCI-H460	M{XLfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MWfJR\|UxRTJ3MT60NVch\|ryP	MYnTRW5ITVJ?
TGBC1TKB	MnrhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MnXJTWM2OD1{NUKuPFc2KM7:TR?=	MlrMV2FPT0WU
NCI-H1304	NGm2U4dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MUDJR\|UxRTJ3Mz6xOVYh\|ryP	M4WzfnNCVkeHUh?=
CAL-27	MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NW\MPGlxUUN3ME2yOVMvPDh3IN88US=>	M{jyOnNCVkeHUh?=
NCI-H187	NV62emNZT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NES0T2JKSzVyPUK1Ok44PiEQvF2=	NV;iXoZvW0GQR1XS
HSC-2	Ml\vS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MoDqTWM2OD1{NUiuOVg1KM7:TR?=	NWrUephPW0GQR1XS
CAL-39	NVnvS\|lUT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NFjhT5FKSzVyPUK2NE4zPzJizszN	NF;5eXNUSU6JRWK=
HuH-7	M33IUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M3PacGlEPTB;Mk[wMlk6PiEQvF2=	Mln2V2FPT0WU
MMAC-SF	MlfYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NUXBdZp7UUN3ME2yOlEvOTl{IN88US=>	M1nR[HNCVkeHUh?=
VA-ES-BJ	Mn7BS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MlnFTWM2OD1{NkGuPVE5KM7:TR?=	NHvRfWdUSU6JRWK=
A673	M3y0b2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MmPqTWM2OD1{NkeuNFI2KM7:TR?=	NFOwUHZUSU6JRWK=
LU-165	MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MV3JR\|UxRTJ4Nz65OFEh\|ryP	MofYV2FPT0WU
CAL-12T	M1zWOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NVTINm05UUN3ME2yOlgvOzZ4IN88US=>	NYfBT3FlW0GQR1XS
RD	MornS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NIi4bnlKSzVyPUK2PU4yOTlizszN	M1nlXnNCVkeHUh?=
MDA-MB-468	M1G4TWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NHHvV4ZKSzVyPUK2PU4{OzNizszN	NH7aSoFUSU6JRWK=
LN-405	NWLYbYYyT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M2rRRWlEPTB;Mk[5MlcxQCEQvF2=	NXfsWWRUW0GQR1XS
MHH-CALL-2	NVvKdlFsT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MXvJR\|UxRTJ4OT65NkDPxE1?	Mk[1V2FPT0WU
ES3	M4LKUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NGn2foVKSzVyPUK3NE4{PThizszN	M{nqV3NCVkeHUh?=
SK-MEL-3	MnfDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Mn23TWM2OD1{N{WuOFU4KM7:TR?=	NFT4V5FUSU6JRWK=
TE-10	Mlm5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M1Xse2lEPTB;Mke2MlQ{QSEQvF2=	NFPnZpZUSU6JRWK=
BEN	NUKzbnlZT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NW[1O2s{UUN3ME2yO\|YvPDZzIN88US=>	MUfTRW5ITVJ?
NB69	MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MUTJR\|UxRTJ5Nz60NFUh\|ryP	NFjlTINUSU6JRWK=
CAMA-1	M4fHcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MXPJR\|UxRTJ5OD6yO\|kh\|ryP	NV:xcGY4W0GQR1XS
NCI-H1792	NWTH[FRjT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MmTlTWM2OD1{N{muNVg4KM7:TR?=	M2r1O3NCVkeHUh?=
UACC-893	NI[wZ3NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NEDidVlKSzVyPUK4NE42PCEQvF2=	MnjGV2FPT0WU
TGW	NVPweFJvT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NUXveWx{UUN3ME2yPFMvODV6IN88US=>	NYHUbJVNW0GQR1XS
SH-4	NHrLTJBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NILlSpJKSzVyPUK4N{4yOjNizszN	MlzlV2FPT0WU
NCI-H2009	M2ThTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M4TpZmlEPTB;MkizMlk2OyEQvF2=	M4HrcXNCVkeHUh?=
T84	M1j0VWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MnniTWM2OD1{OESuOlY2KM7:TR?=	MV7TRW5ITVJ?
EW-7	Moq5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NXP1NoNLUUN3ME2yPFUvOjN{IN88US=>	MUPTRW5ITVJ?
NCI-H1882	NInqXJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NYW2TFFHUUN3ME2yPFYvODN3IN88US=>	MmT2V2FPT0WU
GMS-10	NU\sflVDT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M1vLOWlEPTB;Mki3MlE5OyEQvF2=	M3[yZnNCVkeHUh?=
HC-1	MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MVLJR\|UxRTJ7MD62NFIh\|ryP	MoXCV2FPT0WU
ABC-1	MkXrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MojPTWM2OD1{OUGuNFY6KM7:TR?=	NITiTmhUSU6JRWK=
HuP-T3	NYLqdJRIT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MXLJR\|UxRTJ7Mj6xOFYh\|ryP	MWjTRW5ITVJ?
HT-1197	NWfKVGhUT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NY[xR3NHUUN3ME2yPVIvQDd7IN88US=>	M4OxZXNCVkeHUh?=
SHP-77	MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NXTlWlh6UUN3ME2yPVUvPTl5IN88US=>	NG\qempUSU6JRWK=
NCI-H524	MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M2\zOGlEPTB;Mkm1Mlc3QSEQvF2=	M2rSd3NCVkeHUh?=
SW626	MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NYji[nNTUUN3ME2yPVYvOTF3IN88US=>	MYnTRW5ITVJ?
NCI-H2347	NVzzOXoyT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MYDJR\|UxRTJ7Nj60NlUh\|ryP	MX\TRW5ITVJ?
U251	NX;YdZliT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M3zqemlEPTB;Mkm4MlQ{QCEQvF2=	MUjTRW5ITVJ?
RL95-2	MlH0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M3Tn[mlEPTB;M{CwMlI1PyEQvF2=	M3jxTnNCVkeHUh?=
C2BBe1	MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				Mm\oTWM2OD1\|MECuOlkyKM7:TR?=	NF\YflJUSU6JRWK=
HLE	NYDMXFY1T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MlnpTWM2OD1\|MEGuPFE5KM7:TR?=	NGnST4xUSU6JRWK=
COLO-680N	MnPBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Mk\XTWM2OD1\|MEKuPFk{KM7:TR?=	NFKxVWlUSU6JRWK=
PLC-PRF-5	M3XIe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NV7nbpVwUUN3ME2zNFQvQTB5IN88US=>	MYLTRW5ITVJ?
SCC-15	M1LyZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M37UO2lEPTB;M{C2MlAyPyEQvF2=	MnnJV2FPT0WU
ECC12	M4LGfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NEPSUFRKSzVyPUOxNE4zPTRizszN	M3G3[XNCVkeHUh?=
A388	NGPFOmRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M3;pRWlEPTB;M{GyMlAzOiEQvF2=	M2DtbXNCVkeHUh?=
ES1	NX;mNINCT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MUDJR\|UxRTNzMj6xPFkh\|ryP	MkPxV2FPT0WU
J-RT3-T3-5	M{LEXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NInV[HpKSzVyPUOxN{42OjFizszN	NUTOXXhMW0GQR1XS
SNU-475	MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M2nXS2lEPTB;M{G0MlA6OSEQvF2=	NWf4OVJ[W0GQR1XS
647-V	MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M1\S[WlEPTB;M{G0MlY4OyEQvF2=	NVPhNHhLW0GQR1XS
IMR-5	NHi4XYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MXTJR\|UxRTNzNT6zPEDPxE1?	NHrZTJBUSU6JRWK=
EW-24	M4ftcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NX;tPXZ3UUN3ME2zNlAvODdizszN	NWnYfYhzW0GQR1XS
CAL-51	M2Kwbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MlT2TWM2OD1\|MkGuOFA{KM7:TR?=	MYXTRW5ITVJ?
HD-MY-Z	MkjaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Ml\QTWM2OD1\|MkGuOFA6KM7:TR?=	NVz5blh3W0GQR1XS
EW-13	MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MUDJR\|UxRTN{Mj60NlQh\|ryP	MnXoV2FPT0WU
SK-N-FI	NYrJeYNYT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M3PveWlEPTB;M{KyMlQ2OiEQvF2=	Ml\HV2FPT0WU
BHY	NFX4S4RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M{\QSmlEPTB;M{KzMlE4PSEQvF2=	MVrTRW5ITVJ?
OCUB-M	NFfOeolIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MVnJR\|UxRTN{Mz60N\|Qh\|ryP	MmPQV2FPT0WU
HCC1954	M1HWdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MmqxTWM2OD1\|MkOuOVgzKM7:TR?=	NYPhcJhDW0GQR1XS
SK-MEL-24	NEDqOmxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NUG1XVJGUUN3ME2zNlQvOTFzIN88US=>	MXTTRW5ITVJ?
NTERA-S-cl-D1	MnvLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M3;aT2lEPTB;M{K2MlQ5QSEQvF2=	NGPYVXpUSU6JRWK=
SK-MEL-30	M{PT[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MmLjTWM2OD1\|Mk[uO\|M5KM7:TR?=	MoTCV2FPT0WU
LS-123	NGLTc5NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MkOyTWM2OD1\|MkiuNVY1KM7:TR?=	Mmr4V2FPT0WU
SF268	NIfxVFVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NIOxemxKSzVyPUOzNE4zPjVizszN	MmLPV2FPT0WU
BT-474	NHvVSYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MXXJR\|UxRTN\|Mj60NVgh\|ryP	NELoSWFUSU6JRWK=
NCI-H1522	MmLqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MWTJR\|UxRTN\|ND6zN\|kh\|ryP	NEnOfWhUSU6JRWK=
LC-2-ad	NHXTcWlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NV76dFBIUUN3ME2zN\|YvPTlzIN88US=>	MlLHV2FPT0WU
LAN-6	MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MmXVTWM2OD1\|M{[uPVc4KM7:TR?=	NILFNlBUSU6JRWK=
ARH-77	MoLWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MY\JR\|UxRTN\|Nz6zNkDPxE1?	M{LQV3NCVkeHUh?=
HuO9	NFfRO3VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NWDmR5NHUUN3ME2zN\|cvPDdizszN	MlS0V2FPT0WU
MLMA	MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NWLo[mNUUUN3ME2zN\|gvOTV3IN88US=>	MkGzV2FPT0WU
Raji	MnvzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MnTITWM2OD1\|M{iuN\|gh\|ryP	M{[wRXNCVkeHUh?=
GT3TKB	NH\jepdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M4m3dGlEPTB;M{O4MlQyOiEQvF2=	NV7aWlREW0GQR1XS
NCI-H441	Mlj4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Ml3OTWM2OD1\|NEGuOFE5KM7:TR?=	MWfTRW5ITVJ?
NCI-H2030	NUP6b40{T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NXO1ZpRDUUN3ME2zOFEvPjB7IN88US=>	M1ywdnNCVkeHUh?=
VM-CUB-1	Mn3mS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MVXJR\|UxRTN2Mj62N\|Yh\|ryP	M{\2OHNCVkeHUh?=
KP-4	M2D2[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NEXlZ4xKSzVyPUO0N{44OzNizszN	MVjTRW5ITVJ?
PF-382	NE\wO4tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M1;Lc2lEPTB;M{S0MlQzOiEQvF2=	NUG2UJhHW0GQR1XS
NB13	NGjNZYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NWi0Xod6UUN3ME2zOFUvPThizszN	M3PR[HNCVkeHUh?=
D-502MG	MnzkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MkLvTWM2OD1\|NEWuPFEzKM7:TR?=	NFLkeolUSU6JRWK=
CAL-54	M{n6T2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MlX2TWM2OD1\|NEWuPFc6KM7:TR?=	NFruR5pUSU6JRWK=
DOHH-2	NFrCSYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NUDTeI9JUUN3ME2zOFYvPjVizszN	NWnDZotxW0GQR1XS
SK-PN-DW	MlvrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NU\pXZk1UUN3ME2zOFcvPDJ4IN88US=>	M13HS3NCVkeHUh?=
NCI-H720	MnP2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NUjXZndCUUN3ME2zOFkvQDR4IN88US=>	NEjEUZlUSU6JRWK=
SW1990	MnnuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M4Pj[2lEPTB;M{WxMlI5KM7:TR?=	NULyUFhRW0GQR1XS
NCI-H2196	NUDaV5djT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MXTJR\|UxRTN3Mj62NlQh\|ryP	NVq4VmpzW0GQR1XS
P30-OHK	NUPmVVdzT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NGTUOFVKSzVyPUO1N{4xPjNizszN	NGHTPGFUSU6JRWK=
NCI-H358	M1XKbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NIfXb2pKSzVyPUO1OU4{PTZizszN	MkfXV2FPT0WU
CW-2	NIOzUWFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MlXrTWM2OD1\|NU[uOVI6KM7:TR?=	M3:wSHNCVkeHUh?=
COLO-678	MkL5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Mo\CTWM2OD1\|NUeuPFY{KM7:TR?=	MnXZV2FPT0WU
NCI-H2126	NXnpPIhOT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NFHxemJKSzVyPUO1PE42OjFizszN	NITIWlBUSU6JRWK=
DMS-53	NFf2XoZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NY[1XXBmUUN3ME2zOVgvPzFzIN88US=>	MlS3V2FPT0WU
NCI-H1838	MlrXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M4nRPGlEPTB;M{W5Mlk5PyEQvF2=	NVv0VJQ3W0GQR1XS
SJSA-1	MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M3;ISWlEPTB;M{[wMlk{QSEQvF2=	MUfTRW5ITVJ?
ChaGo-K-1	M4HOeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M3rxOmlEPTB;M{[zMlkzPCEQvF2=	M2i4T3NCVkeHUh?=
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U-266	NWTQdpFmT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MXLJR\|UxRTN5Mz6xN\|Ih\|ryP	NX3nZ5FFW0GQR1XS
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HCC2157	M1;5W2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M{WyeGlEPTB;M{e4MlE3OSEQvF2=	MV3TRW5ITVJ?
COR-L88	M4XxbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NIfWUXpKSzVyPUO4N{43PzdizszN	MmLkV2FPT0WU
NCI-H596	MlOzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NX\NfnR3UUN3ME2zPFUvOzRizszN	NEO0[m9USU6JRWK=
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P12-ICHIKAWA	NGLjOYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NXv0blRRUUN3ME21NVEvPDF4IN88US=>	MoTlV2FPT0WU
NCI-H1694	MlPRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M2HmVWlEPTB;NUGyMlQ{QSEQvF2=	NHG4N41USU6JRWK=
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NCI-H1436	Mn3oS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NX;ubGFMUUN3ME21NlMvODZ2IN88US=>	NV7CeHdiW0GQR1XS
NCI-H510A	MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MWfJR\|UxRTV{ND62PVYh\|ryP	MmT1V2FPT0WU
NCI-H2081	Ml\SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MkO0TWM2OD13MkWuOVE{KM7:TR?=	NU\KfXZRW0GQR1XS
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HSC-4	NVS1[opZT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NXuybXNEUUN3ME21N\|kvOjl\|IN88US=>	MliwV2FPT0WU
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EVSA-T	M2rZdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NFfqRnpKSzVyPUW0N{43QDRizszN	MVrTRW5ITVJ?
NCI-H889	M2rESmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NIrLUoZKSzVyPUW0O{4zOyEQvF2=	NFLGWo9USU6JRWK=
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EW-11	M2[2fmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				Ml[2TWM2OD13NUKuN\|k6KM7:TR?=	M1zGOnNCVkeHUh?=
UACC-812	NV3HS243T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M{\LNWlEPTB;NUW5MlM6OSEQvF2=	Mnf2V2FPT0WU
CAL-148	MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				Ml\iTWM2OD13NkWuNFg6KM7:TR?=	MUDTRW5ITVJ?
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KARPAS-45	MofnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M4[zSWlEPTB;NkG4MlIzOSEQvF2=	MYDTRW5ITVJ?
HT	NIf3bJFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MVzJR\|UxRTZ{Mj63PFUh\|ryP	MmT3V2FPT0WU
NCI-H226	NF3PTWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				Ml3YTWM2OD14MkiuN\|U{KM7:TR?=	NEXjdnBUSU6JRWK=
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NCI-SNU-16	MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NIP5Z4VKSzVyPU[4NE41PjJizszN	NW\rZ24{W0GQR1XS
NCI-SNU-1	M2rHVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NV;ROVA2UUN3ME22PVAvOTd{IN88US=>	NX;ZUVFrW0GQR1XS
U-87-MG	M2TM[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MXjJR\|UxRTZ7ND61PFUh\|ryP	MmX2V2FPT0WU
KM-H2	NH3YNJFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M13ZdmlEPTB;Nkm5MlA2QSEQvF2=	MoPNV2FPT0WU
DEL	NYDxPZpKT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				Mn;YTWM2OD15MECuPFM5KM7:TR?=	MkTDV2FPT0WU
KARPAS-422	MmrDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M{fkcGlEPTB;N{i5MlMyPSEQvF2=	M4W4NnNCVkeHUh?=
BC-3	NXHUe\|U5T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				Ml[wTWM2OD16MEWuNlA{KM7:TR?=	MULTRW5ITVJ?
NCI-H1155	MmnyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MX7JR\|UxRThzOD6wOVkh\|ryP	NYexbpBwW0GQR1XS
NCI-H1581	MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NIfpWYJKSzVyPUmwNE4zOzFizszN	M3zP[XNCVkeHUh?=

... Click to View More Cell Line Experimental Data

体内研究

CHIR-99021按30 mg/kg 剂量口服处理患2型糖尿病的啮齿类动物模型，增强葡萄糖代谢，处理3-4小时后，最大血浆葡萄糖减少近150 mg/dl，而血浆胰岛素保持或低于对照水平。CHIR-99021按16 或 48 mg/kg剂量口服给药ZDF大鼠，1小时后，再口服葡萄糖，显著改善糖耐量，16 mg/kg 和 48 mg/kg处理组的血浆葡萄糖分别减少14％和33％，较高剂量CHIR-99021处理，再口服葡萄糖，还可以降低高血糖。^[1]CHIR-99021处理移植小鼠或人造血干细胞（HSC）的受体小鼠，显著增强造血重建功能，说明GSK-3是一种特异性的HSC活性调节剂。^[4]

激酶实验： ^[1]	+ 展开无细胞激酶实验: 聚丙烯96孔板中每孔充满了含27 nM GSK-3α 或 29 nM GSK-3β, 和 0.5 μM 生物素-CREB 肽底物的300 μL 缓冲液 (50 mM Tris HCl, 10 mM MgCl₂, 1 mM EGTA, 1 mM 二硫苏糖醇, 25 mM β-glycerophosphate, 1 mM NaF, 0.01% BSA, pH 7.5) 。各种浓度CHIR-99021加入3.5 μL DMSO中，随后加入50 μL ATP储存液，使所有无细胞实验中ATP终浓度为1 μM。温育后，100 μL等分试样按一式三份转移至每孔含100 μL 50 μM ATP和 20 mM EDTA的Combiplate 8孔板中。1小时后，使用用PBS将孔洗涤5次，填充200 μL闪烁液，密封，放置30分钟后，然后在闪烁计数器中计数。所有步骤在室温下进行。
细胞实验： ^[3]	+ 展开 Cell lines: INS-1E Concentrations: 溶于DMSO, 终浓度为20 μM Incubation Time: 1, 或 4 天 Method: 细胞在饥饿培养基（只含5mM葡萄糖，1％胎牛血清）中维持24小时。然后使用不同浓度的CHIR-99021处理细胞的1天或4天。通过使用CyQuant染料进行细胞DNA染色，测量细胞数，当结合DNA就会发出荧光。温育30分钟后，使用FLUOstar Optima酶标仪测量荧光。通过BrdUrd掺入法测定细胞复制。最后4小时，BrdUrd标记溶液加入到培养基中，然后使用FixDenat溶液固定细胞，与单克隆anti-BrdUrd-POD抗体温育。每孔加入底物溶液后，在微孔板发光检测仪上使用Analyst HT检测系统测量光发射。 (Only for Reference)
动物实验： ^[1]	+ 展开 Animal Models: 雌性db/db小鼠或雄性2型糖尿病ZDF大鼠 Formulation: 在20mM柠檬酸盐缓冲的15％Captisol中配制成溶液，或在0.5％羧甲基纤维素中配制成悬浮液 Dosages: ~48 mg/kg Administration: 口服处理 (Only for Reference)

参考文献

溶解度 (25°C)

体外	DMSO	93 mg/mL (185.33 mM)
	Ethanol	2 mg/mL (3.98 mM)
	Water	Insoluble
体内	从左到右依次将纯溶剂加入产品，现配现用(数据来自Selleck实验检测而非文献)： 5% DMSO+30% PEG 300+ddH2O	24mg/mL

* 溶解度检测是由Selleck技术部门检测的，可能会和文献中提供的溶解度有所差异，这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据 Download CHIR-99021 (CT99021) HCl SDF

分子量	501.8
化学式	C₂₂H₁₈Cl₂N_8.HCl
CAS号	1797989-42-4
稳定性	3 years -20°C powder
稳定性	2 years -80°C in solvent
别名	N/A

计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为:

质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

质量

浓度

体积

分子量
=

×

×

*在配置溶液时，请务必参考Selleck产品标签上、MSDS / COA（可在Selleck的产品页面获得）批次特异的分子量使用本工具。

稀释计算器

用本工具协助配置特定浓度的溶液，使用的计算公式为：

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入输出 )

C1

V1

C2

V2
×

=

×

在配置溶液时，请务必参考Selleck产品标签上、MSDS / COA（可在Selleck的产品页面获得）批次特异的分子量使用本工具。.

连续稀释计算器方程

连续稀释
初始浓度:
稀释倍数:

计算结果

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):

分子量计算器

通过输入化合物的化学式来计算其分子量：

注：化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量	浓度	体积	分子量
=	×	×
计算

技术支持

在订购、运输、储存和使用我们的产品的任何阶段，您遇到的任何问题，均可以通过拨打我们的热线电话400-668-6834，或者技术支持邮箱tech@selleck.cn，直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题，请给我们留言。

常见问题及建议解决方法

问题 1：
I recently purchased CHIR 99021 to inject mice intraperitoneally. The data sheet says using 10% captisol for in vivo use. Is it for IP injection? Or do you have other solutions to suggest to use for in vivo IP injection of CHIR 99021?
回答：
The formulation of 15% Captisol is for oral gavage, and S2924 CHIR-99021 (CT99021) HCl in it is a suspension. S2924 CHIR-99021 (CT99021) HCl can be dissolved in 5% DMSO+30% PEG 300+ddH2O at 24mg/ml as a clear solution for IP injection.
问题 2：
How about the half-life of this compound? If it is necessary for daily treatment when the compound is used in long-term experiment?
回答：
Please change the culture medium each day to add the new comound in it if the duration is more than 72h.
问题 3：
What is the difference between S2924 and S1263? Which one is better for differentiation?
回答：
S1263 is the free base format of Chir-99021, while S2924 is the HCl salt format. They have the same biological activity but are slightly different in solubility.

GSK-3 Signaling Pathway Map

GSK-3 Inhibitors with Unique Features

选择性强的GSK-3抑制剂

TWS119 : GSK-3β-selective, IC50 of 30 nM.
活性最高的GSK-3抑制剂

CHIR-98014 : GSK-3α, IC50=0.65 nM; GSK-3β, IC50=0.58 nM.
用于临床的GSK-3抑制剂

Tideglusib : Phase II for Alzheimer's disease.
最新的GSK-3抑制剂

AZD1080 : Orally active, brain permeable GSK3 inhibitor, inhibits human GSK3α and GSK3β with K_i of 6.9 nM and 31 nM, respectively.

研究领域

产品类型

CHIR-99021 (CT99021) HCl

客户使用Selleck该产品发表文献73篇：

客户使用该产品的9个实验数据：

产品安全说明书

GSK-3抑制剂选择性比较

生物活性

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

参考文献

溶解度 (25°C)

化学数据 Download CHIR-99021 (CT99021) HCl SDF

计算器

摩尔浓度计算器

质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

稀释计算器

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

连续稀释计算器方程

连续稀释

计算结果

分子量计算器

总分子量：g/mol

摩尔浓度计算器

技术支持

常见问题及建议解决方法

GSK-3 Signaling Pathway Map

GSK-3 Inhibitors with Unique Features

相关GSK-3产品