Fungal

抑制剂选择性比较

Fungal产品

目录号 产品描述 文献引用 实验数据
S1517

Natamycin

Natamycin (Pimaricin) 是一种天然存在的三唑类抗真菌药物。具有极少或无味道干扰。

S2476

Itraconazole (R 51211)

Itraconazole (R 51211) 是一种三唑类抗真菌药物,是CYP3A4的有效抑制剂,IC50为6.1 nM。Itraconazole 是一个有效的Hedgehog (Hh)信号通路的拮抗剂。Itraconazole 可通过诱导自噬来抑制恶性胶质瘤的生长。

S1331

Fluconazole (UK 49858)

Fluconazole (UK 49858)是一种羊毛甾醇14 alpha去甲基化酶 抑制剂,抑制了麦角固醇的形成,用于治疗和预防浅表性和全身性真菌感染。

S1934

Nystatin (Fungicidin)

Nystatin (Fungicidin) 是一种多烯类抗真菌剂,常常被用作oropharyngeal candidosis的局部治疗剂。

S5080New

Neticonazole

Neticonazole (SS717) 是一种选择性的针对 exosome 形成和分泌的抑制剂。 Neticonazole具有Neticonazole的抗真菌和抗肿瘤活性。

S3588New

Hexylene glycol

Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) 是一种衍生自丙酮的氧化溶剂,已广泛用于工业化学品和化妆品中。Hexylene glycol 具有抗菌 antibacterial 和抗真菌 antifungal 的特性。

S3595New

D-Gluconic acid

D-Gluconic acid 是一种抗真菌 antifungal 药。

S3532New

AN-2718

AN-2718 is an inhibitor of fungal growth that blocks protein synthesis via the oxaborole tRNA trapping (OBORT) mechanism.

S0938New

Sakuranetin

Sakuranetin is a rice flavonoid phytoalexin that shows antifungal activity. Sakuranetin has anti-inflammatory and antioxidative activities. Sakuranetin ameliorates LPS-induced acute lung injury.

S0832New

Dimboa

Dimboa (2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one) is an antifungal agent used in crops.

S0971New

Kakuol

Kakuol is a natural compound extracted from the rhizomes of Asarum sieboldii with antifungal activity.

S3373New

Deoxylapachol

Deoxylapachol is a major cytotoxic component of New Zealand brown alga, Landsburgia quercifolia with antifungal and anti-cancer activity.

S3307New

Galangin 3-methyl ether

Galangin 3-methyl ether (3-O-Methylgalangin, 3-Methylgalangin) 分离自 Lychnophora markgravii 的地上部分,具有很强的抗细菌和抗真菌作用。

S1725

Terbinafine

Terbinafine (SF 86-327) 用于治疗真菌感染,可以杀死真菌或防止其生长。

S1606

Clotrimazole

Clotrimazole (BAY b 5097, FB 5097)是一种合成的抗真菌药物,是imidazole的广谱衍生物。

S1956

Miconazole Nitrate

Miconazole (NSC 169434) Nitrate是一种咪唑类抗真菌剂,外用或静脉输液。

S1666

Flucytosine

Flucytosine (5-Fluorocytosine, 5-FC, 5-Fluorocytosine, NSC 103805, Ro 2-9915)是氟嘧啶类似物, 是抗菌药,作用于人白色念珠菌(C. albicans)时 IC50 为0.12 μg/mL。

S2557

Terbinafine HCl

Terbinafine HCl (KWD 201)通过抑制角鲨烯环氧酶抑制了麦角固醇的合成,用作抗真菌药物。

S3073

Caspofungin (MK-0991) Acetate

Caspofungin Acetate (MK-0991, L-743872)是一种脂肽类抗真菌β-1,3-glucan synthase抑制剂。

S2528

Ciclopirox

Ciclopirox 是一种合成的抗真菌药物。

S3019

Ciclopirox ethanolamine

Ciclopirox ethanolamine作为一种铁离子螯合剂,具有广谱抗真菌作用。

S2535

Econazole nitrate

Econazole Nitrate (NSC 243115) 是一种咪唑类抗真菌药物。

S1854

Bifonazole

Bifonazole (Bay h 4502) 是一种抗真菌剂和前列腺芳香化酶抑制剂,IC50为1.6 μM。

S3079

Atovaquone

Atovaquone (Atavaquone)用于治疗或预防肺孢子菌肺炎,弓形虫病, 疟疾和巴贝西虫。

S1997

Liranaftate

Liranaftate 是一种角鲨烯环氧酶抑制剂具有抗真菌活性。

S3161

Sertaconazole nitrate

Sertaconazole nitrate (FI-7045)是一种外用广谱抗真菌药,是用来治疗表面皮肤和粘膜感染的辅助用药

S2031

Fenticonazole Nitrate

Fenticonazole Nitrate 是一种唑类抗真菌药物。

S1676

Amorolfine HCl

Amorolfine HCl是一种抗真菌药物。

S4075

Zinc Pyrithione

Zinc pyrithione (OM-1563)是一种抗真菌和抗细菌药物,可以通过阻断质子泵破坏膜转运。

S2536

Miconazole

Miconazole 是一种咪唑类抗真菌药物。

S1910

Tioconazole

Tioconazole (UK-20349) 是一种抗真菌药物,IC50为1.7 μM。

S4120

Sulconazole Nitrate

Sulconazole Nitrate 是一种咪唑衍生物,具有广谱抗真菌活性。

S3154

Butenafine HCl

Butenafine HCl (KP-363)是一种合成的苄胺类抗真菌药物,通过抑制甾醇合成,通过抑制角鲨烯环氧酶,而发挥作用。

S3156

Naftifine HCl

Naftifine HCl是一种烯丙基胺类抗真菌药,外用治疗足癣,股癣,体癣,通过抑制角鲨烯2,3-环氧酶选择性抑制甾醇的生物合成。

S1833

Butoconazole nitrate

Butoconazole nitrate (RS-35887)是一种抗真菌剂,抑制PHA刺激下人外周血淋巴细胞中细胞因子(如IL-2, TNFα, IFN 和 GM-CSF)的分泌,IC50分别为7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL 和 7.6 μg/mL。

S4806

Potassium 1-Naphthaleneacetate

Potassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens.

S9200

Pneumocandin B0

Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.

S0917

Allosecurinin

Allosecurinine (Phyllochrysine) 是一种从 M.indicaM.discoidea 分离的具有抗真菌活性的Securinega生物碱。

S6254

Hydrocinnamic acid

Hydrocinnamic acid (3-phenylpropionic acid, Benzylacetic acid)是苯丙氨酸代谢途径中氧化还原酶的底物。它是一种抗真菌剂和代谢物。

S4581

Triacetin

Triacetin (Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane) 是一种甘油三酸酯,具有杀真菌作用。

S5213

Piroctone Olamine

Piroctone Olamine (piroctone ethanolamine) is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff,fungal infections.

S5553

Kasugamycin hydrochloride

Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.

S5944

Butenafine

Butenafine是合成的苄胺抗真菌剂。

S5359

Butoconazole

Ethyl chrysanthemate is an allelochemical compound used as an attractant.

S8095

Tubercidin

Tubercidin (7-deaza-adenosine),腺苷类似物,是一种核苷抗生素。它可掺入到DNA中,抑制聚合酶,因此抑制DNA复制RNA、蛋白合成。Tubercidin还具有抗真菌和抗病毒活性。

S3966

Nifuratel

Nifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action.

S4970

Nerol

Nerol (Cis-Geraniol, Neryl alcohol)是存在于多种香精油如柠檬草和槐花中的单萜化合物。

S3829

Isoalantolactone

Isoalantolactone, one of the major sesquiterpene lactone compounds, is isolated from the roots of Anula helenium and possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia.

S2058

Tolnaftate

Tolnaftate 是一种合成的硫代氨基甲酸酯,用作抗真菌剂。

S4584

Butylparaben

Butylparaben (Butyl parahydroxybenzoate, Butyl 4-hydroxybenzoate) 是一种常在化妆品中被用作抗菌防腐剂的化合物。

S0770

Camalexin

Camalexin, a phytoalexin isolated from Camelina sativa and Arabidopsis (Cruciferae), can induce reactive oxygen species (ROS) production. Camalexin has antibacterial, antifungal, antiproliferative and anticancer activities.

S6118

Terpinen-4-ol

Terpinen-4-ol是一种天然存在的单萜,是茶树油的主要活性成分,具有多种生物活性如抗真菌活性。

S4996

Tavaborole (AN-2690)

Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity.

S5271

Suloctidil

Suloctidil, a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation, is a peripheral vasodilator and a potential antifungal agent.

S4755

lanosterol

Lanosterol是一种四环三萜,它可由所有的动物、真菌类固醇衍生而来。

S3778

Patchouli alcohol

Patchouli alcohol (Patchoulol, Patchouli camphor), an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis.

S4963

Purpurin

Purpurin (1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin)是从茜草根和其他茜草科植物家族中分离出的天然色素。它具有抗血管生成、抗菌、抗氧化活性。Purpurin 可有效地抑制CYP1A1、CYP1A2 和 CYP1B1。

S4178

Climbazole

Climbazole是一种广谱的咪唑类抗真菌药剂,具有抗头皮屑的效果。

S6270

2-Aminoisobutyric acid

2-Aminoisobutyric acid (NSC-16590, 2-Methylalanine, H-Aib-OH)是一种稀有的、非蛋白氨基酸,是嘧啶代谢的终产物,随着尿液排出,在一些真菌来源的抗生素中有发现。

S4187

Salicylanilide

Salicylanilides (WR10019)是一组具有广泛的生物活性的化合物,具有抗病毒效力,抗菌(包括抗分枝杆菌),和抗真菌活性。

S3676

Carbendazim

Carbendazim (Mercarzole, Carbendazole) is a broad-spectrum systemic antimycotic and can be used to control a broad range of diseases on field crops, fruits, and vegetables, including sclerotinia rot of canola, wheat head blight, peanut leaf spot, and SB on rice. Its mode of action is to inhibit the formation of mitotic microtubules in of fungi.

S4258

Luliconazole

Luliconazole是一种广谱抗真菌药物。

S9350

Ethyl 4-Methoxycinnamate

Ethyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities.

S9057

Sinigrin

Sinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects.

S2534

Isoconazole nitrate

Isoconazole nitrate 是一种唑类抗真菌药物。

S5704

Myclobutanil

Myclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor.

S3705

Chlorobutanol

Chlorobutanol (Chlorbutol, Chloreton, Chloretone, Chlortran|, trichloro-2-methyl-2-propanol)是一种防腐剂、镇静剂、催眠剂和弱的局部麻醉剂,具有抗菌抑菌作用。

S3860

Allicin

Allicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects.

S9072

Sweroside

Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.

S2321

Magnolol

Magnolol (NSC 293099) 是一种在Houpu magnolia (Magnolia officinalis) 树皮中发现的生物活性化合物。它能抑制TNFα诱导的NF-KB的激活。

S6408

Hexetidine

Hexetidine是一种抗细菌和抗真菌剂,具有局部麻醉、止血、除臭、预防牙菌斑作用。

S5033

Terconazole

Terconazole (Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol)是一种新型的、广谱的、三唑抗真菌试剂,主要用于治疗阴道真菌感染。

S5025

Efinaconazole

Efinaconazole (KP-103) 是14 alpha-demethylase的抑制剂。14 alpha-demethylase参与ergosterol的生物合成,ergosterol是真菌细胞膜的成分之一。

S9413

Yangonin

Yangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors.

S5724

Dichlorophen

Dichlorophen (Dichlorophene, Bis(5-chloro-2-hydroxyphenyl)methane) is an anticestodal agent, fungicide, germicide, and antimicrobial agent.

S5829

Monomyristin

Monomyristin (Glyceryl myristate, 2,3-Dihydroxypropyl tetradecanoate)具有抗细菌和抗真菌活性。

S4601

Clioquinol

Clioquinol (Iodochlorhydroxyquin, Chinoform) 是一种具有口服活性的、亲油性的、铜离子结合的卤代8-羟基喹啉(8-hydroxyquinoline),具有抗真菌、抗寄生物以及潜在的抗肿瘤活性。

S6451

Salifungin

Salifungin (Multifungin, Bromosalicylchloranilide)是一种抗真菌剂,在某些个体中可能导致过敏性接触性皮炎。

S3722

Isavuconazole

Isavuconazole (BAL-4815, RO-0094815) 是新型超广谱三唑类化合物,对酵母、霉菌和双态性真菌具有活性,抑制cytochrome P450 (CYP)依赖性的14α-lanosterol脱甲基作用,以此抑制真菌细胞膜麦角固醇的合成。

S5541

Dimetridazole

Dimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds.

S3979

Zinc Undecylenate

Zinc Undecylenate (Zinc diundec-10-enoate, Zinc 10-undecenoate) is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.

S5086

p-Anisaldehyde

p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde),茴芹种子提取物,具有抗真菌活性,对很多酵母和实验室培养基、果泥和果汁中的霉菌菌株具有活性。

S6467

Fosfluconazole

Fosfluconazole是一种水溶性的fluconazole盐酸盐前体药物。Fluconazole是三唑抗真菌药物,用于治疗和组织表面的和系统性真菌感染。

S9444

Tomatine

Tomatine (Lycopersicin) is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties.

S4525

Ethylparaben

Ethylparaben (Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate)是对羟基苯甲酸(p-hydroxybenzoic acid)的乙酯形式,被用作抗真菌防腐剂和食品添加剂。它还是一种化学过敏原,其生理效应是通过增加组胺释放和细胞所介导的免疫反应所实现。

S4878

Neticonazole Hydrochloride

Neticonazole是咪唑类抗真菌剂,用于治疗皮肤真菌感染。

S5845

Chalcone

Chalcone (benzylideneacetophenone, phenyl styryl ketone, benzalacetophenone, β-phenylacrylophenone)是一种芳族酮,是很多重要的生物化合物(chalcones)的中心,具有抗菌、抗肿瘤和消炎活性。

S4793

Cedryl acetate

Cedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.

S5512

Juglone

Juglone (Regianin, 5-Hydroxy-1,4-naphthoquinone), a natural naphthoquinone found in the black walnut and other plants, has moderate antifungal activity and growth-stimulating effects to many types of plants. It sometimes can be used as an herbicide, as a dye for cloth and inks, and as a coloring agent for foods and cosmetics.

S4516

(+)-Camphor

Camphor是一种蜡质的、易燃的、白色或透明的固体,有强烈的香味,通常用于缓解疼痛、减少瘙痒以及治疗真菌感染。它能够激活TRPV1TRPV3

S5373

Pseudolaric Acid B

Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties.

S4843

Potassium acetate

Potassium acetate (Diuretic salt, Potassium ethanoate) is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties.

S4286

Anidulafungin (LY303366)

Anidulafungin (LY303366), 一种echinocandin的衍生物, 抑制glucan synthase的活性, 用作抗真菌药。

S3910

4',7-Dimethoxyisoflavone

4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro.

S4287

Micafungin (FK 463) Sodium

Micafungin Sodium (FK463, Mycamine)是1,3-β-D-葡聚糖合成抑制剂,用作抗真菌的药物。

S4559

Cloxiquine

Cloxiquine (5-Chloro-8-quinolinol, Dermofungin)是一种抗细菌、抗真菌、抗衰老和抗痨药物。

S3985

Methyl 4-hydroxybenzoate

Methyl 4-hydroxybenzoate (Methylparaben, Methyl p-hydroxybenzoate, Nipagin) 是一种抗真菌剂,应用于多种化妆品、个人护理用品和食品防腐剂。

S0491

Manogepix (E1210)

Manogepix (E1210, MGX, APX001A) 是一种广谱的、口服活性的抗真菌剂,可抑制 Gwt1/Gwt1p (GPI锚定壁转移蛋白1),该蛋白在真菌细胞壁完整性中起重要作用。

S3990

Trans-Anethole

Trans-anethole (4-Propenylanisole)是苯丙烯衍生物,存在于多种香精油、包括茴香油中。它具有神经调节、抗焦虑、抗氧化、抗真菌、抗炎症和免疫调节活性。

S1442

Voriconazole (UK-109496)

Voriconazole (UK-109496) 是类似于氟康唑和伊曲康唑的新型三唑衍生物,其作用是通过抑制真菌 cytochrome P-450 依赖性的,14-alpha-sterol demethylase 介导的 麦角固醇的合成。

S5174

Kojic acid

Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.

S5083

Lentinan

Lentinan (A823605, Bromoduline),分离纯化自香菇子实体水煮提取物,是一种真菌多糖免疫调制剂,具有抗肿瘤活性。

目录号 产品描述 文献引用 实验数据
S1517

Natamycin

Natamycin (Pimaricin) 是一种天然存在的三唑类抗真菌药物。具有极少或无味道干扰。

S2476

Itraconazole (R 51211)

Itraconazole (R 51211) 是一种三唑类抗真菌药物,是CYP3A4的有效抑制剂,IC50为6.1 nM。Itraconazole 是一个有效的Hedgehog (Hh)信号通路的拮抗剂。Itraconazole 可通过诱导自噬来抑制恶性胶质瘤的生长。

S1331

Fluconazole (UK 49858)

Fluconazole (UK 49858)是一种羊毛甾醇14 alpha去甲基化酶 抑制剂,抑制了麦角固醇的形成,用于治疗和预防浅表性和全身性真菌感染。

S1934

Nystatin (Fungicidin)

Nystatin (Fungicidin) 是一种多烯类抗真菌剂,常常被用作oropharyngeal candidosis的局部治疗剂。

S5080New

Neticonazole

Neticonazole (SS717) 是一种选择性的针对 exosome 形成和分泌的抑制剂。 Neticonazole具有Neticonazole的抗真菌和抗肿瘤活性。

S3588New

Hexylene glycol

Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) 是一种衍生自丙酮的氧化溶剂,已广泛用于工业化学品和化妆品中。Hexylene glycol 具有抗菌 antibacterial 和抗真菌 antifungal 的特性。

S3595New

D-Gluconic acid

D-Gluconic acid 是一种抗真菌 antifungal 药。

S3532New

AN-2718

AN-2718 is an inhibitor of fungal growth that blocks protein synthesis via the oxaborole tRNA trapping (OBORT) mechanism.

S0938New

Sakuranetin

Sakuranetin is a rice flavonoid phytoalexin that shows antifungal activity. Sakuranetin has anti-inflammatory and antioxidative activities. Sakuranetin ameliorates LPS-induced acute lung injury.

S0832New

Dimboa

Dimboa (2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one) is an antifungal agent used in crops.

S0971New

Kakuol

Kakuol is a natural compound extracted from the rhizomes of Asarum sieboldii with antifungal activity.

S3373New

Deoxylapachol

Deoxylapachol is a major cytotoxic component of New Zealand brown alga, Landsburgia quercifolia with antifungal and anti-cancer activity.

S3307New

Galangin 3-methyl ether

Galangin 3-methyl ether (3-O-Methylgalangin, 3-Methylgalangin) 分离自 Lychnophora markgravii 的地上部分,具有很强的抗细菌和抗真菌作用。

S1725

Terbinafine

Terbinafine (SF 86-327) 用于治疗真菌感染,可以杀死真菌或防止其生长。

S1606

Clotrimazole

Clotrimazole (BAY b 5097, FB 5097)是一种合成的抗真菌药物,是imidazole的广谱衍生物。

S1956

Miconazole Nitrate

Miconazole (NSC 169434) Nitrate是一种咪唑类抗真菌剂,外用或静脉输液。

S1666

Flucytosine

Flucytosine (5-Fluorocytosine, 5-FC, 5-Fluorocytosine, NSC 103805, Ro 2-9915)是氟嘧啶类似物, 是抗菌药,作用于人白色念珠菌(C. albicans)时 IC50 为0.12 μg/mL。

S2557

Terbinafine HCl

Terbinafine HCl (KWD 201)通过抑制角鲨烯环氧酶抑制了麦角固醇的合成,用作抗真菌药物。

S3073

Caspofungin (MK-0991) Acetate

Caspofungin Acetate (MK-0991, L-743872)是一种脂肽类抗真菌β-1,3-glucan synthase抑制剂。

S2528

Ciclopirox

Ciclopirox 是一种合成的抗真菌药物。

S3019

Ciclopirox ethanolamine

Ciclopirox ethanolamine作为一种铁离子螯合剂,具有广谱抗真菌作用。

S2535

Econazole nitrate

Econazole Nitrate (NSC 243115) 是一种咪唑类抗真菌药物。

S1854

Bifonazole

Bifonazole (Bay h 4502) 是一种抗真菌剂和前列腺芳香化酶抑制剂,IC50为1.6 μM。

S3079

Atovaquone

Atovaquone (Atavaquone)用于治疗或预防肺孢子菌肺炎,弓形虫病, 疟疾和巴贝西虫。

S1997

Liranaftate

Liranaftate 是一种角鲨烯环氧酶抑制剂具有抗真菌活性。

S3161

Sertaconazole nitrate

Sertaconazole nitrate (FI-7045)是一种外用广谱抗真菌药,是用来治疗表面皮肤和粘膜感染的辅助用药

S2031

Fenticonazole Nitrate

Fenticonazole Nitrate 是一种唑类抗真菌药物。

S1676

Amorolfine HCl

Amorolfine HCl是一种抗真菌药物。

S4075

Zinc Pyrithione

Zinc pyrithione (OM-1563)是一种抗真菌和抗细菌药物,可以通过阻断质子泵破坏膜转运。

S2536

Miconazole

Miconazole 是一种咪唑类抗真菌药物。

S1910

Tioconazole

Tioconazole (UK-20349) 是一种抗真菌药物,IC50为1.7 μM。

S4120

Sulconazole Nitrate

Sulconazole Nitrate 是一种咪唑衍生物,具有广谱抗真菌活性。

S3154

Butenafine HCl

Butenafine HCl (KP-363)是一种合成的苄胺类抗真菌药物,通过抑制甾醇合成,通过抑制角鲨烯环氧酶,而发挥作用。

S3156

Naftifine HCl

Naftifine HCl是一种烯丙基胺类抗真菌药,外用治疗足癣,股癣,体癣,通过抑制角鲨烯2,3-环氧酶选择性抑制甾醇的生物合成。

S1833

Butoconazole nitrate

Butoconazole nitrate (RS-35887)是一种抗真菌剂,抑制PHA刺激下人外周血淋巴细胞中细胞因子(如IL-2, TNFα, IFN 和 GM-CSF)的分泌,IC50分别为7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL 和 7.6 μg/mL。

S4806

Potassium 1-Naphthaleneacetate

Potassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens.

S9200

Pneumocandin B0

Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.

S0917

Allosecurinin

Allosecurinine (Phyllochrysine) 是一种从 M.indicaM.discoidea 分离的具有抗真菌活性的Securinega生物碱。

S6254

Hydrocinnamic acid

Hydrocinnamic acid (3-phenylpropionic acid, Benzylacetic acid)是苯丙氨酸代谢途径中氧化还原酶的底物。它是一种抗真菌剂和代谢物。

S4581

Triacetin

Triacetin (Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane) 是一种甘油三酸酯,具有杀真菌作用。

S5213

Piroctone Olamine

Piroctone Olamine (piroctone ethanolamine) is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff,fungal infections.

S5553

Kasugamycin hydrochloride

Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.

S5944

Butenafine

Butenafine是合成的苄胺抗真菌剂。

S5359

Butoconazole

Ethyl chrysanthemate is an allelochemical compound used as an attractant.

S8095

Tubercidin

Tubercidin (7-deaza-adenosine),腺苷类似物,是一种核苷抗生素。它可掺入到DNA中,抑制聚合酶,因此抑制DNA复制RNA、蛋白合成。Tubercidin还具有抗真菌和抗病毒活性。

S3966

Nifuratel

Nifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action.

S4970

Nerol

Nerol (Cis-Geraniol, Neryl alcohol)是存在于多种香精油如柠檬草和槐花中的单萜化合物。

S3829

Isoalantolactone

Isoalantolactone, one of the major sesquiterpene lactone compounds, is isolated from the roots of Anula helenium and possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia.

S2058

Tolnaftate

Tolnaftate 是一种合成的硫代氨基甲酸酯,用作抗真菌剂。

S4584

Butylparaben

Butylparaben (Butyl parahydroxybenzoate, Butyl 4-hydroxybenzoate) 是一种常在化妆品中被用作抗菌防腐剂的化合物。

S0770

Camalexin

Camalexin, a phytoalexin isolated from Camelina sativa and Arabidopsis (Cruciferae), can induce reactive oxygen species (ROS) production. Camalexin has antibacterial, antifungal, antiproliferative and anticancer activities.

S6118

Terpinen-4-ol

Terpinen-4-ol是一种天然存在的单萜,是茶树油的主要活性成分,具有多种生物活性如抗真菌活性。

S4996

Tavaborole (AN-2690)

Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity.

S5271

Suloctidil

Suloctidil, a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation, is a peripheral vasodilator and a potential antifungal agent.

S4755

lanosterol

Lanosterol是一种四环三萜,它可由所有的动物、真菌类固醇衍生而来。

S3778

Patchouli alcohol

Patchouli alcohol (Patchoulol, Patchouli camphor), an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis.

S4963

Purpurin

Purpurin (1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin)是从茜草根和其他茜草科植物家族中分离出的天然色素。它具有抗血管生成、抗菌、抗氧化活性。Purpurin 可有效地抑制CYP1A1、CYP1A2 和 CYP1B1。

S4178

Climbazole

Climbazole是一种广谱的咪唑类抗真菌药剂,具有抗头皮屑的效果。

S6270

2-Aminoisobutyric acid

2-Aminoisobutyric acid (NSC-16590, 2-Methylalanine, H-Aib-OH)是一种稀有的、非蛋白氨基酸,是嘧啶代谢的终产物,随着尿液排出,在一些真菌来源的抗生素中有发现。

S4187

Salicylanilide

Salicylanilides (WR10019)是一组具有广泛的生物活性的化合物,具有抗病毒效力,抗菌(包括抗分枝杆菌),和抗真菌活性。

S3676

Carbendazim

Carbendazim (Mercarzole, Carbendazole) is a broad-spectrum systemic antimycotic and can be used to control a broad range of diseases on field crops, fruits, and vegetables, including sclerotinia rot of canola, wheat head blight, peanut leaf spot, and SB on rice. Its mode of action is to inhibit the formation of mitotic microtubules in of fungi.

S4258

Luliconazole

Luliconazole是一种广谱抗真菌药物。

S9350

Ethyl 4-Methoxycinnamate

Ethyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities.

S9057

Sinigrin

Sinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects.

S2534

Isoconazole nitrate

Isoconazole nitrate 是一种唑类抗真菌药物。

S5704

Myclobutanil

Myclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor.

S3705

Chlorobutanol

Chlorobutanol (Chlorbutol, Chloreton, Chloretone, Chlortran|, trichloro-2-methyl-2-propanol)是一种防腐剂、镇静剂、催眠剂和弱的局部麻醉剂,具有抗菌抑菌作用。

S3860

Allicin

Allicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects.

S9072

Sweroside

Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.

S2321

Magnolol

Magnolol (NSC 293099) 是一种在Houpu magnolia (Magnolia officinalis) 树皮中发现的生物活性化合物。它能抑制TNFα诱导的NF-KB的激活。

S6408

Hexetidine

Hexetidine是一种抗细菌和抗真菌剂,具有局部麻醉、止血、除臭、预防牙菌斑作用。

S5033

Terconazole

Terconazole (Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol)是一种新型的、广谱的、三唑抗真菌试剂,主要用于治疗阴道真菌感染。

S5025

Efinaconazole

Efinaconazole (KP-103) 是14 alpha-demethylase的抑制剂。14 alpha-demethylase参与ergosterol的生物合成,ergosterol是真菌细胞膜的成分之一。

S9413

Yangonin

Yangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors.

S5724

Dichlorophen

Dichlorophen (Dichlorophene, Bis(5-chloro-2-hydroxyphenyl)methane) is an anticestodal agent, fungicide, germicide, and antimicrobial agent.

S5829

Monomyristin

Monomyristin (Glyceryl myristate, 2,3-Dihydroxypropyl tetradecanoate)具有抗细菌和抗真菌活性。

S4601

Clioquinol

Clioquinol (Iodochlorhydroxyquin, Chinoform) 是一种具有口服活性的、亲油性的、铜离子结合的卤代8-羟基喹啉(8-hydroxyquinoline),具有抗真菌、抗寄生物以及潜在的抗肿瘤活性。

S6451

Salifungin

Salifungin (Multifungin, Bromosalicylchloranilide)是一种抗真菌剂,在某些个体中可能导致过敏性接触性皮炎。

S3722

Isavuconazole

Isavuconazole (BAL-4815, RO-0094815) 是新型超广谱三唑类化合物,对酵母、霉菌和双态性真菌具有活性,抑制cytochrome P450 (CYP)依赖性的14α-lanosterol脱甲基作用,以此抑制真菌细胞膜麦角固醇的合成。

S5541

Dimetridazole

Dimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds.

S3979

Zinc Undecylenate

Zinc Undecylenate (Zinc diundec-10-enoate, Zinc 10-undecenoate) is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.

S5086

p-Anisaldehyde

p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde),茴芹种子提取物,具有抗真菌活性,对很多酵母和实验室培养基、果泥和果汁中的霉菌菌株具有活性。

S6467

Fosfluconazole

Fosfluconazole是一种水溶性的fluconazole盐酸盐前体药物。Fluconazole是三唑抗真菌药物,用于治疗和组织表面的和系统性真菌感染。

S9444

Tomatine

Tomatine (Lycopersicin) is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties.

S4525

Ethylparaben

Ethylparaben (Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate)是对羟基苯甲酸(p-hydroxybenzoic acid)的乙酯形式,被用作抗真菌防腐剂和食品添加剂。它还是一种化学过敏原,其生理效应是通过增加组胺释放和细胞所介导的免疫反应所实现。

S4878

Neticonazole Hydrochloride

Neticonazole是咪唑类抗真菌剂,用于治疗皮肤真菌感染。

S5845

Chalcone

Chalcone (benzylideneacetophenone, phenyl styryl ketone, benzalacetophenone, β-phenylacrylophenone)是一种芳族酮,是很多重要的生物化合物(chalcones)的中心,具有抗菌、抗肿瘤和消炎活性。

S4793

Cedryl acetate

Cedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.

S5512

Juglone

Juglone (Regianin, 5-Hydroxy-1,4-naphthoquinone), a natural naphthoquinone found in the black walnut and other plants, has moderate antifungal activity and growth-stimulating effects to many types of plants. It sometimes can be used as an herbicide, as a dye for cloth and inks, and as a coloring agent for foods and cosmetics.

S4516

(+)-Camphor

Camphor是一种蜡质的、易燃的、白色或透明的固体,有强烈的香味,通常用于缓解疼痛、减少瘙痒以及治疗真菌感染。它能够激活TRPV1TRPV3

S5373

Pseudolaric Acid B

Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties.

S4843

Potassium acetate

Potassium acetate (Diuretic salt, Potassium ethanoate) is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties.

S4286

Anidulafungin (LY303366)

Anidulafungin (LY303366), 一种echinocandin的衍生物, 抑制glucan synthase的活性, 用作抗真菌药。

S3910

4',7-Dimethoxyisoflavone

4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro.

S4287

Micafungin (FK 463) Sodium

Micafungin Sodium (FK463, Mycamine)是1,3-β-D-葡聚糖合成抑制剂,用作抗真菌的药物。

S4559

Cloxiquine

Cloxiquine (5-Chloro-8-quinolinol, Dermofungin)是一种抗细菌、抗真菌、抗衰老和抗痨药物。

S3985

Methyl 4-hydroxybenzoate

Methyl 4-hydroxybenzoate (Methylparaben, Methyl p-hydroxybenzoate, Nipagin) 是一种抗真菌剂,应用于多种化妆品、个人护理用品和食品防腐剂。

S0491

Manogepix (E1210)

Manogepix (E1210, MGX, APX001A) 是一种广谱的、口服活性的抗真菌剂,可抑制 Gwt1/Gwt1p (GPI锚定壁转移蛋白1),该蛋白在真菌细胞壁完整性中起重要作用。

S3990

Trans-Anethole

Trans-anethole (4-Propenylanisole)是苯丙烯衍生物,存在于多种香精油、包括茴香油中。它具有神经调节、抗焦虑、抗氧化、抗真菌、抗炎症和免疫调节活性。

目录号 产品描述 文献引用 实验数据
S1442

Voriconazole (UK-109496)

Voriconazole (UK-109496) 是类似于氟康唑和伊曲康唑的新型三唑衍生物,其作用是通过抑制真菌 cytochrome P-450 依赖性的,14-alpha-sterol demethylase 介导的 麦角固醇的合成。

S5174

Kojic acid

Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.

S5083

Lentinan

Lentinan (A823605, Bromoduline),分离纯化自香菇子实体水煮提取物,是一种真菌多糖免疫调制剂,具有抗肿瘤活性。