BMS-754807

For research use only. Not for use in humans.

目录号:S1124

BMS-754807 Chemical Structure

CAS No. 1001350-96-4

BMS-754807是一种有效的IGF-1R/InsR可逆性抑制剂,在无细胞试验中IC50为1.8 nM/1.7 nM,对Met (c-Met),Aurora A/B,TrkA/B和Ron作用稍弱,对Flt3, Lck,MK2,PKA,PKC等几乎没有抑制活性。Phase 2。

规格 价格 库存 购买数量  
10mM (1mL in DMSO) RMB 2211.3 现货
RMB 1480.09 现货
RMB 2214.12 现货
RMB 6299.66 现货
RMB 16953.3 现货
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客户使用Selleck生产的BMS-754807发表文献35篇:

产品安全说明书

IGF-1R抑制剂选择性比较

生物活性

产品描述 BMS-754807是一种有效的IGF-1R/InsR可逆性抑制剂,在无细胞试验中IC50为1.8 nM/1.7 nM,对Met (c-Met),Aurora A/B,TrkA/B和Ron作用稍弱,对Flt3, Lck,MK2,PKA,PKC等几乎没有抑制活性。Phase 2。
特性 胰岛素样生长因子-1R/IR家族激酶的多重抑制剂
靶点
Insulin Receptor [1]
(Cell-free assay)
IGF-1R [1]
(Cell-free assay)
TrkB [1]
(Cell-free assay)
Met [1]
(Cell-free assay)
TrkA [1]
(Cell-free assay)
1.7 nM 1.8 nM 4.1 nM 5.6 nM 7.4 nM
体外研究

BMS-754807 有效抑制人类多种不同组织来源的肿瘤细胞系的生长,包括间充质(尤文氏肉瘤,横纹肌肉瘤,神经母细胞瘤,和脂肪肉瘤),上皮(乳腺,肺,胰腺,结肠,和胃),和造血(多发性骨髓瘤和白血病)组织,IC50值从5 nM 到 365 nM。BMS-754807 抑制 IGF-1R-Sal 细胞和 RH41细胞增殖,IC50分别为7 nM 和5 nM。BMS-754807作用于IGF-1R-Sal, Rh41 和 Geo细胞,抑制IGF-1R磷酸化,IC50分别为13 nM, 6 nM 和 21 nM。BMS-754807作用于 IGF-1R-Sal, Rh41 和Geo细胞,抑制Akt磷酸化,IC50 分别为22 nM, 13 nM 和 16 nM。BMS-754807诱导Rh41细胞凋亡。[1] BMS-754807作用于IGF-Sal 细胞系,抑制IGF-1R (IC50 = 13nM) 和下游靶点Akt (IC50 = 22nM) 和MAPK(IC50 = 13nM) 的磷酸化。[2] 在儿科临床前期试验计划(PPTP)中,BMS-754807作用于23种细胞系,平均EC50值为0.62 µM。[3]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
IGF-Sal MYHLbY5ie2ViYYPzZZk> MXjpcohq[mm2czD0bIUheGixc4Doc5J6dGG2aX;uJI9nKEmJRj2xVkApUUN3MDC9JFE{dk1rIHHu[EB1cGViZH;3cpN1emWjbTD0ZZJo\XS|IFHreEApUUN3MDC9JFIzdk1rIHHu[EBOSVCNIDjJR|UxKD1iMUPuUUk> M4\vc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{e4NFI1Lz5zOUe3PFAzPDxxYU6=
IGF-Sal NETJcZlIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= MVXJR|UxRTdibl2= M4DFclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{e4NFI1Lz5zOUe3PFAzPDxxYU6=
CCRF-CEM (ALL) MWfHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? NFXtSFV,PSEQvF2= MkTYSG1UVw>? NV\MXYkzUUN3ME2xMlI{QSEQvF2= M4P6bVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
PC3 MkjZS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? Ml;pglUh|ryP M3\pTmROW09? MXnJR|UxRTBwOU[1JO69VQ>? NYXqSGQyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
JD NGO4[YtIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= NHriSW5,PSEQvF2= MlrGSG1UVw>? MnHnTWM2OD1yLkO5NUDPxE1? MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
DU145 NV3qfY9HT3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= NXjYc5RQhjVizszN M37MW2ROW09? M2HwXWlEPTB;MT60OlUh|ryP NULGWGlrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
KAG MVTHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? NF\lbVh,PSEQvF2= MYnEUXNQ NF3se49KSzVyPUGuOlY2KM7:TR?= MlTpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
K-562 (CML) NHf6cmtIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= MnjrglUh|ryP M3H2Z2ROW09? MknRTWM2OD1{LkOwNkDPxE1? M4nycVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
B6-P210 (Murine ALL) MYnHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? MV7+OUDPxE1? Mn7lSG1UVw>? M3;0fmlEPTB;MT6yPVMh|ryP NHu5clg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
LN CAP-FGC MnTMS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? NGHIUWp,PSEQvF2= NH\lOGNFVVOR Mme5TWM2OD1zLkSzOEDPxE1? M2\6NlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
VW MnXkS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? NEjaXIh,PSEQvF2= NVzzdpNITE2VTx?= MWnJR|UxRTBwMEG5JO69VQ>? NWm5co94RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
MV411 (B Myelomonocytic) Mk\NS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? NYPBWIVvhjVizszN MlS3SG1UVw>? MYrJR|UxRTBwM{Og{txO MkfIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
MDA-PCa-2b MUPHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? M1\jdJ42KM7:TR?= NH\jbG1FVVOR MWLJR|UxRTBwMEm4JO69VQ>? M{f1SlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
LG MX;Hdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? MmjGglUh|ryP NX\ldFdVTE2VTx?= NGe3b2pKSzVyPUCuNFM5KM7:TR?= MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
RS411 (B cell precursor-ALL) NI\zOYlIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= MXP+OUDPxE1? NIrYXWtFVVOR NXTVXJdJUUN3ME2wMlExOiEQvF2= NYrNcXlkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
22-r-1 MVrHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? M2K3UJ42KM7:TR?= NGq3PGtFVVOR MXLJR|UxRTBwMUe1JO69VQ>? NX7DTlc5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
5838 NHvjXohIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= M{DqdZ42KM7:TR?= M1XNbmROW09? MYLJR|UxRTBwMEO0JO69VQ>? NX;YOmtQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
P388 (Murine) NH7QUJBIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= NXW1emRlhjVizszN NEK0NGpFVVOR MWHJR|UxRTRwMkeg{txO NFnmPGE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
A2780/S MWTHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? M1vuOp42KM7:TR?= M3flWWROW09? MknLTWM2OD1yLkGyNkDPxE1? NVuwWWgxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
RDES M2LSVWdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 MnHCglUh|ryP NV3SWm1pTE2VTx?= M2\hUGlEPTB;MD6wNVIh|ryP NVu0UXNZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
B6-T315I (Murine B-ALL) M3P1fWdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 M{nQc542KM7:TR?= NGj4NFhFVVOR Mn7nTWM2OD1{LkizJO69VQ>? MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
TOV 112D NGTxT4RIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= M{TpXZ42KM7:TR?= MVLEUXNQ MnzITWM2OD1{LkG0OkDPxE1? M{K1OFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
TC32 NXe1VWZYT3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= NETMOop,PSEQvF2= NE[3Z4xFVVOR NGDsVYVKSzVyPUCuNFA5KM7:TR?= MoH1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
HL60 (acute myelocytic) Ml2wS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? MlOyglUh|ryP NGftPG5FVVOR NELrb2dKSzVyPUCuNVIh|ryP M{O5VlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
TOV 21G MX;Hdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? NF[2blZ,PSEQvF2= M1HJW2ROW09? MknsTWM2OD12LkK3PUDPxE1? NWi0Z4dERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
TC71 M1W4dmdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 MlfoglUh|ryP NGKxXW9FVVOR NF\jR|JKSzVyPUCuNFE1KM7:TR?= NX6xW3F{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
HPN-ALL (T-cell) M3joPWdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 MnjhglUh|ryP NWfifXF6TE2VTx?= NVvvSIxOUUN3ME2wMlUzKM7:TR?= M1;WTlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
A2780R NWHnNJJkT3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= NUnKeFFYhjVizszN MU\EUXNQ M1m1OmlEPTB;MT61OlQh|ryP NH\rWGc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
Rh1 MmPHS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? NV\iN2R3hjVizszN M4q2eGROW09? MnTTTWM2OD1yLkCyO{DPxE1? MoftQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
Kasumi-1 (acute myeloid) M{S0Z2dzd3e2aDDpcohq[mm2b4L5JIF{e2G7 MoW1glUh|ryP NHnxb|FFVVOR MX\JR|UxRTBwMU[g{txO MkD1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
sk-ov-3 MW\Hdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? M1jhV542KM7:TR?= MUnEUXNQ NGf6fVJKSzVyPUWuNUDPxE1? MlXnQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
ME MVzHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? NUXPfVVPhjVizszN MVjEUXNQ MlzUTWM2OD1yLkCxOUDPxE1? NWrpclFCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
L1210 (Murine lymphocytic) NHTweZlIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= M2nXZp42KM7:TR?= NHTUe|BFVVOR MX;JR|UxRTJwM{mg{txO MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
sw-626 MkjoS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? NH[1eZh,PSEQvF2= MkDVSG1UVw>? MYfJR|UxRTJwM{C2JO69VQ>? NYjxTJdkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
CTR MmDlS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? NInFTIF,PSEQvF2= M3XNcWROW09? NXPEV4UxUUN3ME2wMlI2OyEQvF2= M3\vNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
ML2 (Myelomonocytic) Ml7FS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? MmnPglUh|ryP NYfMfHhyTE2VTx?= Ml72TWM2OD1yLkC5JO69VQ>? MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
ovcar-3 M1fvN2dzd3e2aDDpcohq[mm2b4L5JIF{e2G7 NUTqTmtKhjVizszN M17EVGROW09? M2ruPWlEPTB;NTFOwG0> MmO0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
Rh36 NX31S|RPT3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= M2joV542KM7:TR?= MkfhSG1UVw>? M4SzdmlEPTB;MT60N|Ih|ryP MnXkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
MOLM-13 (acute myeloid) Mof6S5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? MlLsglUh|ryP M4qxdWROW09? M3rnNmlEPTB;MD60NkDPxE1? MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
ovcar-4 MmDRS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? NWGxbVNqhjVizszN MUnEUXNQ NUDDSVB4UUN3ME2xJO69VQ>? NYiwclhVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
Rh41 NVnnUFdoT3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= Mn\EglUh|ryP MWjEUXNQ NGnTZ3NKSzVyPUCuNFA2KM7:TR?= MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
Mutz 2 (acute myeloid) NInjVFRIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= MonsglUh|ryP NGXRc3BFVVOR NWnYfGxnUUN3ME2xMlE2KM7:TR?= MmTFQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
ovcar-5 MoT1S5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? NUTU[JByhjVizszN MknnSG1UVw>? MX\JR|UxRTBwMEWg{txO NEe3UZM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
RD1 NIXUUlZIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= M4LGS542KM7:TR?= MoTiSG1UVw>? NHPHZW9KSzVyPUCuNFY5KM7:TR?= NIfjZlg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
OCI-AML 2 (acute myeloid) NWrkbIpvT3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= MYX+OUDPxE1? MkGySG1UVw>? M2LCeWlEPTB;Mz6zN{DPxE1? M{fpb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
786-O NES2eVRIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= MVT+OUDPxE1? NVu0c3dETE2VTx?= MlzOTWM2OD1zLk[0O{DPxE1? MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
A673 NX\Ecnc1T3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= MWr+OUDPxE1? NH;vVGpFVVOR NHThV3RKSzVyPUCuOFA5KM7:TR?= NY\6b2VURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
TALL-1 (T-cell) M4jxXmdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 M2Hwbp42KM7:TR?= MlX5SG1UVw>? MkTkTWM2OD1zLkK4JO69VQ>? NUjORWFiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
151-B NHfjXmFIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= NHjUXFl,PSEQvF2= NID0OHhFVVOR NV\meFlFUUN3ME2yMlY4KM7:TR?= MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
PFSK-1 MXrHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? M3\Dd542KM7:TR?= NHfMUIRFVVOR NFHXeWVKSzVyPUCuNVMzKM7:TR?= MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
THP-1 MmPhS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? NGjQR4x,PSEQvF2= MUXEUXNQ MoTaTWM2OD14LkW4JO69VQ>? MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
HEK293 M2npPWdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 MYn+OUDPxE1? NVLiSFVUTE2VTx?= M37tOmlEPTB;MD65NVUh|ryP NXzxcHA3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
DAOY MVfHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? NViyOIh{hjVizszN NX7vc5hrTE2VTx?= NEHJR2RKSzVyPUGuPVc6KM7:TR?= NIPmO3U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
SET2 MlTBS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? M3npfp42KM7:TR?= M330SmROW09? MWnJR|UxRTBwMkm4JO69VQ>? Mo\YQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
HTB-46 NHjwNlhIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= MnjaglUh|ryP M3O4[mROW09? MlT6TWM2OD13LkK1JO69VQ>? MoqyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
SK-NAS NYr1dIJzT3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= MYX+OUDPxE1? MlXYSG1UVw>? NVqwWlk2UUN3ME2wMlQ6PyEQvF2= NX\WelN3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
CTLL2 MlnnS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? NWHMZoRlhjVizszN MWHEUXNQ MnTHTWM2OD5zLkCwJO69VQ>? NXewV5kyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
HTB-47 Mnv6S5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? MX\+OUDPxE1? NGW0V|dFVVOR NHPrbm5KSzVyPUKuNFU3KM7:TR?= MoDnQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
LAN-1 NHnmOZdIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= MUX+OUDPxE1? Mk\FSG1UVw>? NFrae4FKSzVyPUCuNFQh|ryP NFftNZU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
ST486 MmXFS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? M1eyZp42KM7:TR?= NFfpU4NFVVOR Mk\YTWM2OD1zLkG5JO69VQ>? NECyOIE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
HS766T MXPHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? MmrZglUh|ryP MYHEUXNQ NGXCVmdKSzVyPUKuNFAyKM7:TR?= MYG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
IMR-32 NVi5eJprT3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= MUP+OUDPxE1? NVPiS|hjTE2VTx?= MV3JR|UxRTBwMk[xJO69VQ>? NWrSRWVvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
Daudi (Burkitt's) M2LkNWdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 M2L6Tp42KM7:TR?= NHrXSnRFVVOR MWPJR|UxRTJwNkO3JO69VQ>? NVXtR4Z4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
Aspc-1 M4TQVWdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 NI\2dpV,PSEQvF2= NFLNdpBFVVOR NWTSR3dZUUN3ME2wMlM4QSEQvF2= MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
SK-NSH M4Hn[Wdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 NEn6emp,PSEQvF2= NGTycWNFVVOR MoPjTWM2OD1yLkGzPUDPxE1? MkKzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
MEC-1 (Chronic B cell) MU\Hdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? NHzIenl,PSEQvF2= M{X4emROW09? MoPBTWM2OD1{Lk[zO{DPxE1? Mnq3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
Capan-2 NHrIc|ZIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= MnXIglUh|ryP NVnFSol4TE2VTx?= MoPYTWM2OD1zLke3OEDPxE1? MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
SHSY5Y NImyd3NIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= MmXlglUh|ryP NU\aV|ByTE2VTx?= NI\vfGZKSzVyPUCuNVA3KM7:TR?= MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
U937 (Histioocytic) NFfHRYpIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= NVzEdHg3hjVizszN NI\GeW9FVVOR NUHWcWo1UUN3ME61MlAxKM7:TR?= M{LrflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
Bxpc-1 M13N[Wdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 M2j6Tp42KM7:TR?= NYrBSW9JTE2VTx?= NHrBW3lKSzVyPUGuPVI1KM7:TR?= MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
Bxpc-3 M3[wbGdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 MWn+OUDPxE1? NG[ySJJFVVOR M2\aZmlEPTB-NT6wNEDPxE1? NE\KT4M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
HTB-92 M4DE[Wdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 MXL+OUDPxE1? NEPDbpRFVVOR M1i0R2lEPTB;MT6wNkDPxE1? NWL4flAyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
OCI-LY10 (B-cell) MnfsS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? MkfGglUh|ryP MUTEUXNQ NIPJ[lJKSzVyPUCuOFUh|ryP NVywOmVERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
PANC-1 MnrTS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? MYX+OUDPxE1? M36yTWROW09? MXvJR|UxRjVwMECg{txO NVG4XFlWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
To184.T NI\TVmFIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= NEnPeYV,PSEQvF2= M1HhZmROW09? MkXMTWM2OD1yLkS2PUDPxE1? NEDINIc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
OCI-LY19 (B-cell) MUDHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? M3Lucp42KM7:TR?= MV3EUXNQ NVr6cpJ3UUN3ME2wMlQh|ryP NFHLcpA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
PANC-1 BM MoPNS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? MXr+OUDPxE1? Mme0SG1UVw>? M3vBVWlEPTB-NT6wNEDPxE1? MlHwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
SA-4 NVTnbok3T3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= M4PNc542KM7:TR?= NV;3TpFMTE2VTx?= NGX2NXlKSzVyPUGuN|AyKM7:TR?= MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
RPMI 8226 NWTXOGh7T3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= MknWglUh|ryP MYDEUXNQ NVm5WndNUUN3ME2xMlI6OyEQvF2= NFS4SJM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
HPAF-II NYTyV4N1T3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= MkHiglUh|ryP NH3GPWdFVVOR MYnJR|UxRTBwNkS0JO69VQ>? NH7wR3E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
SHP-77 NEK3XldIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= MUP+OUDPxE1? NFv3N3FFVVOR MmCxTWM2OD1zLki4PEDPxE1? Mk\XQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
U266 B1 MkDpS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? NYP3UWg4hjVizszN NFvSWFVFVVOR MW\JR|UxRTFwNk[5JO69VQ>? NE\5SHk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
Hs700t NWHXd2ZWT3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= MlrxglUh|ryP NXHlUGpXTE2VTx?= MYjJR|UxRTBwMkOxJO69VQ>? M1z4VFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
NCI-446 M2\XZmdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 NFnqXop,PSEQvF2= M3fobGROW09? NXHZNFY6UUN3ME2xMlE2PCEQvF2= NW\4dpl{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
H929 MnLvS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? MV7+OUDPxE1? NHvGNVBFVVOR NEXITYlKSzVyPUCuNFE1KM7:TR?= NGLwU5k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
PL45 M1jQbWdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 MX;+OUDPxE1? MYjEUXNQ MVPJR|UxRTJwMkW1JO69VQ>? Mlj3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
NCI-H383 NIrjZ2lIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= NECzXWJ,PSEQvF2= M4PMemROW09? Ml\RTWM2OD53LkCwJO69VQ>? MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
JJN3 NUjIRmc5T3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= M{e2Xp42KM7:TR?= MVvEUXNQ MlvqTWM2OD1{LkSzN{DPxE1? M1jpblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
SU.86.86 NWi5WpVNT3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= MnfsglUh|ryP NH[yUIFFVVOR MkDrTWM2OD1{Lk[3NkDPxE1? MnvyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
H1299 MorQS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? MlPYglUh|ryP NYDDV4E2TE2VTx?= MVzJR|UxRjVwMECg{txO NYrhW5RtRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
MDA-MB-468 MoDQS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? NIT3OGV,PSEQvF2= M4m0cmROW09? MXLJR|UxRTBwNUC0JO69VQ>? NWjHZWpzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
SW1990 NX2xVGNZT3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= NWTIZ29EhjVizszN NUDXVWxGTE2VTx?= NHPIVo5KSzVyPUCuPFI3KM7:TR?= MnLVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
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MDA-MB-231 M1vJNGdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 M2LFNp42KM7:TR?= Mk\RSG1UVw>? NUH0XFZtUUN3ME2xMlY1QCEQvF2= NYXud|hQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
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MCF-7 MWTHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? MUL+OUDPxE1? M3nqOGROW09? M3:xeWlEPTB;MD6wNVYh|ryP M4XVZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
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BT474 (S) NI\JVHpIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= NFXqfYN,PSEQvF2= NYXBTIpCTE2VTx?= MljsTWM2OD1{LkSwN{DPxE1? MofTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
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SW480 NUDre3JST3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= M{T2O542KM7:TR?= M3XoTGROW09? MWHJR|UxRjVwMECg{txO M3\ySFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
L2987 M4n0[Wdzd3e2aDDpcohq[mm2b4L5JIF{e2G7 MUP+OUDPxE1? NYnUXGd1TE2VTx?= NVXRXHo2UUN3ME2wMlQ1OiEQvF2= NWjHenpFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
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SW403 MUHHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? Mn3MglUh|ryP M1PHTGROW09? MXjJR|UxRTBwMkKg{txO MmfkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
H1437 M33we2dzd3e2aDDpcohq[mm2b4L5JIF{e2G7 MkW0glUh|ryP NXjCbpJ1TE2VTx?= MYHJR|UxRTBwNUKzJO69VQ>? M2fWelxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
BT-20 NV;heHZPT3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= Ml3mglUh|ryP NYHrbYpITE2VTx?= NUPWcHgzUUN3ME2zMlU3OiEQvF2= Ml7RQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
Colo320HSR MXLHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? MXL+OUDPxE1? Mki5SG1UVw>? NWWwbYZ4UUN3ME2wMlAyOSEQvF2= NVXMV|d{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
H2087 MXzHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? NWfsdlVLhjVizszN M1HRd2ROW09? M1fXfGlEPTB-MT6wNEDPxE1? NVvzVZJ3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
HCC1419 NGDMXJBIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= MkjnglUh|ryP NUL0VItOTE2VTx?= NHi5N2VKSzVyPUKuOVE4KM7:TR?= NYHZT4M{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
WiDr NFjaW5dIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= Ml[wglUh|ryP NVi2ZZIxTE2VTx?= NV;xdm9oUUN3ME2wMlA4PiEQvF2= MmfXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7OU[yO|IoRjF7OUm2NlczRC:jPh?=
H661 0.573 NIXTc2xIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= Mn3NglUh|ryP MVXEUXNQ MnrlTWM2OD1yLkW3N{DPxE1? M3XkeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
HCC-38 MX;Hdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? NUHEVIdThjVizszN NFfwZZNFVVOR MWTJR|UxRjVwMECg{txO NWHSZm5GRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5PVYzPzJpPkG5PVk3Ojd{PD;hQi=>
LS174T MoH3S5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? M3rtZp42KM7:TR?= M2D5fmROW09? NXjsT41nUUN3ME2wMlU{PSEQvF2= NEexbJY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm5OlI4Oid-MUm5PVYzPzJ:L3G+
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MDA-MB-157 MoK3S5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? MoPNglUh|ryP MkLKSG1UVw>? M2PGUWlEPTB;MD6wN|Yh|ryP MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
H2052 MUfHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? M2XqT542KM7:TR?= MmLTSG1UVw>? M{jId2lEPTB;MT6wOUDPxE1? MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
MDA-MB-415 MVzHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? NHHHW|h,PSEQvF2= NHnSSmNFVVOR NXTqPIQzUUN3ME61MlAxKM7:TR?= M3TGSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUm2NlczLz5zOUm5OlI4OjxxYU6=
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SK-Hep1 NVjuboJOT3Kxd4ToJIlvcGmkaYTvdpkh[XO|YYm= M2\YXp42KM7:TR?= M4K1XGROW09? NE\MW2FKSzVyPUCuNVQ3KM7:TR?= MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl7NkK3Nkc,OTl7OU[yO|I9N2F-
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TC32 NXvpVXB2eUiWUzDhd5NigQ>? MX;xTHRUKG:oIIDl[IlifHKrYzDjZY5k\XJiY3XscEBtcW6nczD0c{Bq\GWwdHnmfUBufWy2aYDs[UBweHCxcoT1col1cWW|IH\vdkBlenWpIILldJVzeG:|aX7nPkBRemmvYYL5JJNkemWnbjDmc5IhXEN|MjDj[Yxtew>? MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTR|NUGzPUc,Ojl2M{WxN|k9N2F-
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A673 NYPmSWFReUiWUzDhd5NigQ>? MYHxTHRUKG:oIIDl[IlifHKrYzDjZY5k\XJiY3XscEBtcW6nczD0c{Bq\GWwdHnmfUBufWy2aYDs[UBweHCxcoT1col1cWW|IH\vdkBlenWpIILldJVzeG:|aX7nPkBRemmvYYL5JJNkemWnbjDmc5IhSTZ5MzDj[Yxtew>? NVTxcZlMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm0N|UyOzlpPkK5OFM2OTN7PD;hQi=>
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SK-N-SH NXTmdGJueUiWUzDhd5NigQ>? M4PmfpFJXFNib3[gdIVlcWG2cnnjJINidmOncjDj[YxtKGyrbnXzJJRwKGmmZX70bYZ6KG23bITpdIxmKG:ycH;yeJVvcXSrZYOg[o9zKGS{dXegdoVxfXKyb4Ppcoc7KFC{aX3hdpkhe2O{ZXXuJIZweiCVSz3OMXNJKGOnbHzz NVjGVox4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm0N|UyOzlpPkK5OFM2OTN7PD;hQi=>
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wild type fibroblast cells MUPxTHRUKGG|c3H5 Ml72dWhVWyCxZjDw[YRq[XS{aXOgZ4Fv[2W{IHPlcIwhdGmwZYOgeI8hcWSnboTp[pkhdXWudHnwcIUhd3Cyb4L0eY5qfGmnczDmc5Ih\HK3ZzDy[ZB2enCxc3nu[|ohWHKrbXHyfUB{[3KnZX6g[o9zKGOxboTyc4whUGhid3ns[EB1gXCnIH\pZpJw[myjc4SgZ4VtdHN? MmHQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2M{WxN|koRjJ7NEO1NVM6RC:jPh?=
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KYSE-510 MoLqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWXpOIR[UW6qaXLpeIlwdiCxZjDoeY1idiCNWWPFMVUyOCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxKD1iMD61NVc2PSEQvF2u M3\ISlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFU4PTR2OD:nQnNCVkeHUkyvZV4>
TE-1 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYfJcohq[mm2aX;uJI9nKGi3bXHuJHRGNTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OCB;IECuOVQ6PjNizszNMi=> NIHEeI89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2PzV2NEivK|5USU6JRWK8M4E,
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LB996-RCC NVXocokzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWnKO2w{UW6qaXLpeIlwdiCxZjDoeY1idiCOQkm5Ok1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OCB;IECuOVYzOjRizszNMi=> MonwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVc2PDR6Lze+V2FPT0WUPD;hQi=>
TE-441-T M1vnZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYfJcohq[mm2aX;uJI9nKGi3bXHuJHRGNTR2MT3UJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUCgQUAxNjV4M{W1JO69VS5? M37YN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFU4PTR2OD:nQnNCVkeHUkyvZV4>
BC-1 MoHpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXXJcohq[mm2aX;uJI9nKGi3bXHuJGJENTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OCB;IECuOVg4PDVizszNMi=> Mm\DQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVc2PDR6Lze+V2FPT0WUPD;hQi=>
5637 Mn2yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXfJcohq[mm2aX;uJI9nKGi3bXHuJFU3OzdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OCB;IECuOlAxQTJizszNMi=> NFjD[WM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2PzV2NEivK|5USU6JRWK8M4E,
A673 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlGyTY5pcWKrdHnvckBw\iCqdX3hckBCPjd|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTBiPTCwMlYxPDh4IN88UU4> NIDDNmg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2PzV2NEivK|5USU6JRWK8M4E,
OPM-2 M2K4TGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWLJcohq[mm2aX;uJI9nKGi3bXHuJG9RVS1{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTBiPTCwMlYyOTZzIN88UU4> NInIPHc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2PzV2NEivK|5USU6JRWK8M4E,
DK-MG MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmjtTY5pcWKrdHnvckBw\iCqdX3hckBFUy2PRzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyIE2gNE43OTd3MTFOwG0v MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1O|U1PDhxJ{7TRW5ITVJ:L3G+
HGC-27 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml[0TY5pcWKrdHnvckBw\iCqdX3hckBJT0NvMkegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3MDC9JFAvPjJ|N{mg{txONg>? MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1O|U1PDhxJ{7TRW5ITVJ:L3G+
TE-10 M4TadGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUfwVJpUUW6qaXLpeIlwdiCxZjDoeY1idiCWRT2xNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwJF0hOC54M{C2OUDPxE1w MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1O|U1PDhxJ{7TRW5ITVJ:L3G+
VA-ES-BJ NYfqdnhVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn:5TY5pcWKrdHnvckBw\iCqdX3hckBXSS2HUz3CTkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwJF0hOC54M{K0O{DPxE1w MnfiQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVc2PDR6Lze+V2FPT0WUPD;hQi=>
KOSC-2 NYjt[XlVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXvJcohq[mm2aX;uJI9nKGi3bXHuJGtQW0NvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyIE2gNE43Ozd{MTFOwG0v M2rSUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFU4PTR2OD:nQnNCVkeHUkyvZV4>
LB1047-RCC NHj0ZlhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV3Jcohq[mm2aX;uJI9nKGi3bXHuJGxDOTB2Nz3SR2Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NEA:KDBwNkSzOVch|ryPLh?= MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1O|U1PDhxJ{7TRW5ITVJ:L3G+
NCI-H1299 NXvnbJdUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWrJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUK5PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwJF0hOC54NEixOEDPxE1w MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1O|U1PDhxJ{7TRW5ITVJ:L3G+
AN3-CA M{KzRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGnGVIZKdmirYnn0bY9vKG:oIHj1cYFvKEGQMz3DRUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwJF0hOC54NU[0OkDPxE1w NVO3R21pRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTd3NES4M{c,W0GQR1XSQE9iRg>?
MKN45 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFK0[4pKdmirYnn0bY9vKG:oIHj1cYFvKE2NTkS1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUCgQUAxNjZ3OUi3JO69VS5? NIr4UZk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2PzV2NEivK|5USU6JRWK8M4E,
BB30-HNC NF;MOGtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVrJcohq[mm2aX;uJI9nKGi3bXHuJGJDOzBvSF7DJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUCgQUAxNjZ4M{ixJO69VS5? NG\h[5c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2PzV2NEivK|5USU6JRWK8M4E,
HSC-3 NFXRTJhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYXJcohq[mm2aX;uJI9nKGi3bXHuJGhUSy1|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTBiPTCwMlY3QDR|IN88UU4> NV\QN5pKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTd3NES4M{c,W0GQR1XSQE9iRg>?
SNB75 M{HsUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUjJcohq[mm2aX;uJI9nKGi3bXHuJHNPSjd3IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTBiPTCwMlY4Ozd5IN88UU4> NF;qZ5Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2PzV2NEivK|5USU6JRWK8M4E,
NCI-H1770 NFXzeHNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1zaNGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixO|cxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVAhRSByLk[3OFA{KM7:TT6= M{njOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFU4PTR2OD:nQnNCVkeHUkyvZV4>
SW948 NYnFSm45T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXTvdW9IUW6qaXLpeIlwdiCxZjDoeY1idiCVV{m0PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwJF0hOC54OUK2JO69VS5? MnvoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVc2PDR6Lze+V2FPT0WUPD;hQi=>
NCI-H2141 NVPFfWxXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3ryeGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNVQyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVAhRSByLk[5PFE6KM7:TT6= MoO3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVc2PDR6Lze+V2FPT0WUPD;hQi=>
SK-OV-3 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3LkdWlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvT2[tN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwJF0hOC55MUK2OEDPxE1w MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1O|U1PDhxJ{7TRW5ITVJ:L3G+
GI-1 NEfmemRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH34c|FKdmirYnn0bY9vKG:oIHj1cYFvKEeLLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3MDC9JFAvPzJ3MEKg{txONg>? M{LTNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFU4PTR2OD:nQnNCVkeHUkyvZV4>
NCI-H2342 NXvlNnE{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX;LXVR{UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFI{PDJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OCB;IECuO|I5OjlizszNMi=> M{LQeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFU4PTR2OD:nQnNCVkeHUkyvZV4>
NB1 M4DFOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4PFTmlvcGmkaYTpc44hd2ZiaIXtZY4hVkJzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTBiPTCwMlc{OTJzIN88UU4> NXmxSFBRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTd3NES4M{c,W0GQR1XSQE9iRg>?
NCI-H1618 NUP4OHo2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnzwTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG2NVgh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NEA:KDBwN{O5NFMh|ryPLh?= MmPuQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVc2PDR6Lze+V2FPT0WUPD;hQi=>
DMS-273 NWWzfldxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1Owe2lvcGmkaYTpc44hd2ZiaIXtZY4hTE2VLUK3N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwJF0hOC55NEG3OUDPxE1w NXryRpBVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTd3NES4M{c,W0GQR1XSQE9iRg>?
SW48 NHLvNFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NE[5VpVKdmirYnn0bY9vKG:oIHj1cYFvKFOZNEigZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3MDC9JFAvPzR7NkOg{txONg>? NXfVO3RxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTd3NES4M{c,W0GQR1XSQE9iRg>?
RT-112 NXz5RnlpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXXJfGhtUW6qaXLpeIlwdiCxZjDoeY1idiCUVD2xNVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NEA:KDBwN{WxNFgh|ryPLh?= NEfLSZU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2PzV2NEivK|5USU6JRWK8M4E,
NCI-H1734 NVO5[XZjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUnV[VdHUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE4OzRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OCB;IECuO|YzQSEQvF2u MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1O|U1PDhxJ{7TRW5ITVJ:L3G+
SNG-M NYixOVh4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUWzOoZEUW6qaXLpeIlwdiCxZjDoeY1idiCVTletUUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwJF0hOC55OEO5OEDPxE1w NH2wW209[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2PzV2NEivK|5USU6JRWK8M4E,
LS-513 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUTJcohq[mm2aX;uJI9nKGi3bXHuJGxUNTVzMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyIE2gNE44QDV6NzFOwG0v NF35dJM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2PzV2NEivK|5USU6JRWK8M4E,
SCC-4 MnjlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M324cmlvcGmkaYTpc44hd2ZiaIXtZY4hW0OFLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3MDC9JFAvPzh4N{[g{txONg>? NFjpUXU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2PzV2NEivK|5USU6JRWK8M4E,
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MFE-280 NFHteWVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYnJcohq[mm2aX;uJI9nKGi3bXHuJG1HTS1{OECgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3MDC9JFQyNjN5OUSg{txONg>? NEi0[Jg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2PzV2NEivK|5USU6JRWK8M4E,
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PF-382 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVnibZoxUW6qaXLpeIlwdiCxZjDoeY1idiCSRj2zPFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NEA:KDR{LkCyOFIh|ryPLh?= Mnr6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVc2PDR6Lze+V2FPT0WUPD;hQi=>
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MKN7 MkHKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYP5XGRwUW6qaXLpeIlwdiCxZjDoeY1idiCPS163JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUCgQUA1Oi52OUe3JO69VS5? NWftTVB4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTd3NES4M{c,W0GQR1XSQE9iRg>?
CP50-MEL-B NFLTXIZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXy2dlVxUW6qaXLpeIlwdiCxZjDoeY1idiCFUEWwMW1GVC2EIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTBiPTC0Nk43QTBzIN88UU4> MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1O|U1PDhxJ{7TRW5ITVJ:L3G+
K052 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MULJcohq[mm2aX;uJI9nKGi3bXHuJGsxPTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OCB;IESzMlA3QThizszNMi=> NFXiN3I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2PzV2NEivK|5USU6JRWK8M4E,
23132-87 NFPrS4lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWHPcVJsUW6qaXLpeIlwdiCxZjDoeY1idiB{M{GzNk05PyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxKD1iNEOuOVI5PiEQvF2u MnfXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVc2PDR6Lze+V2FPT0WUPD;hQi=>
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Mewo M1vBW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Moq2TY5pcWKrdHnvckBw\iCqdX3hckBO\XexIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTBiPTC0OU42QDd6IN88UU4> NYnnNVRORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTd3NES4M{c,W0GQR1XSQE9iRg>?
RMG-I NIr0O3JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M124NWlvcGmkaYTpc44hd2ZiaIXtZY4hWk2JLVmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3MDC9JFQ2Njd|N{Kg{txONg>? MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1O|U1PDhxJ{7TRW5ITVJ:L3G+
BE-13 Mo[2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYnE[3RtUW6qaXLpeIlwdiCxZjDoeY1idiCERT2xN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwJF0hPDVwOUO5NkDPxE1w Moj1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVc2PDR6Lze+V2FPT0WUPD;hQi=>
SW684 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmDOTY5pcWKrdHnvckBw\iCqdX3hckBUXzZ6NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyIE2gOFcvPDl4OTFOwG0v NVLoZ5E4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTd3NES4M{c,W0GQR1XSQE9iRg>?

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
p-IGFIRRβ/InsRβ / IGFIRβ / p-AKT / AKT / p-ERK / ERK ; 

PubMed: 26136493     


(C) T4105 cells were treated with OSI-906 or BMS-754807 at indicated concentrations for 24 hours, lysed, and subjected to immunoblotting.

26136493
Growth inhibition assay
Cell viability; 

PubMed: 30754629     


Response of SK-CO-1 to various drugs and drug combinations.

30754629
体内研究 BMS-754807(12.5mg/kg,口服)作用于携带 IGF-1R-Sal肿瘤的裸鼠,抑制肿瘤和血清中IGF-1R磷酸化。BMS-754807作用于一组选定的上皮(IGF-1R-Sal, GEO, 和Colo205),造血(JJN3)和间质(RD1和Rh41)移植瘤模型,抑制肿瘤生长,肿瘤生长抑制率从53%至115%不等。[1] BMS-754807 (6.25 mg/kg) 作用于转基因的IGF-Sal肿瘤小鼠模型,完全抑制肿瘤生长,且抑制pIGF-1R 和 pAKT。BMS-754807与小鼠血浆和人类血浆的蛋白结合率分别为98.5% 和95.9%。BMS-754807 (25 mg/kg)作用于携带KT-5 (Wilms), KT-14 (rhabdoid), Rh28 (rhabdomyosarcoma), 和 OS-1移植瘤的小鼠模型,显著抑制肿瘤。[3]

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

激酶实验:[1]
- 合并

激酶抑制实验:

在体外激酶实验中使用重组人类 IGF-1受体酶测定BMS-754807,在生化实验中使用合成肽KKSRGDYMTMQIG 作为磷酸受体底物测定BMS-754807。在Ubottom 384孔板中使用 30 μL实验缓冲液 (100 mM Hepes pH 7.4, 10 mM MgCl2, 0.015% Brij35 and 4 mM DTT)来进行酶活测定。通过结合ATP,1.5 μM 荧光标记肽底物, 酶和BMS-754807而开始反应,反应持续60分钟。加入EDTA终止反应。通过电泳分离荧光底物和磷酸化产物,然后在Caliper LabChip 3000上分析反应混合物。通过对剂量反应曲线进行非线性回归分析而获得IC50值。
细胞实验:[1]
- 合并
  • Cell lines: IGF-1R-Sal, RH41 和 Geo 细胞系
  • Concentrations: 365 nM
  • Incubation Time: 72 小时
  • Method: 细胞按最佳密度培养在RPMI + GLUTAMAX培养基中,培养基中含有有10% 热灭活的胎牛血清(FBS),10mMHepes,青霉素和链霉素。BMS-754807处理细胞72小时后,通过测定3H-胸甘渗透到DNA中的程度而测评细胞增殖。结果表示为IC50。
    (Only for Reference)
动物实验:[1]
- 合并
  • Animal Models: 携带IGF-1R-Sal, GEO, Colo205, JJN3, RD1 或 Rh41 肿瘤的裸鼠
  • Dosages: 150 mg/kg
  • Administration: 口服
    (Only for Reference)

溶解度 (25°C)

体外 DMSO 92 mg/mL (199.35 mM)
Water Insoluble
Ethanol '''92 mg/mL
体内 从左到右依次将纯溶剂加入产品,现配现用(数据来自Selleck实验检测而非文献):
2% DMSO+30% PEG 300+ddH2O
5mg/mL

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 461.49
化学式

C23H24FN9O

CAS号 1001350-96-4
储存条件 粉状
溶于溶剂
别名 N/A

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系Selleck为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % ddH2O
计算重置

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

技术支持

在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-668-6834,或者技术支持邮箱tech@selleck.cn,直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题,请给我们留言。

  • * 必填项

IGF-1R Signaling Pathway Map

IGF-1R Inhibitors with Unique Features

相关IGF-1R产品

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID