Vorinostat (SAHA)

For research use only. Not for use in humans.

目录号:S1047 别名: MK0683, Suberoylanilide hydroxamic acid 中文名称:伏立诺他

Vorinostat (SAHA) Chemical Structure

CAS No. 149647-78-9

Vorinostat (suberoylanilide hydroxamic acid, SAHA, MK0683)是一种HDAC抑制剂,无细胞试验中IC50为~10 nM。Vorinostat 会抑制高效的HPV-18 DNA扩增。

规格 价格 库存 购买数量  
10mM (1mL in DMSO) RMB 1558.77 现货
RMB 1198.15 现货
RMB 1794.86 现货
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客户使用Selleck生产的Vorinostat (SAHA)发表文献454篇:

产品安全说明书

HDAC抑制剂选择性比较

生物活性

产品描述 Vorinostat (suberoylanilide hydroxamic acid, SAHA, MK0683)是一种HDAC抑制剂,无细胞试验中IC50为~10 nM。Vorinostat 会抑制高效的HPV-18 DNA扩增。
特性 Vorinostat是广谱HDAC活性抑制剂,抑制I和II类酶 。
靶点
HDAC [1]
(Cell-free assay)
~10 nM
体外研究

Vorinostat是小分子量(<300)线性肟酸,抑制HDAC活性,包括乙酰化组蛋白和非组蛋白的积累,抑制培养细胞的增殖,且抑制肿瘤生长。Vorinostat通过结合到酶的活性位点而抑制 HDAC活性。Vorinostat 抑制多种转化细胞增殖(包括 淋巴瘤,多发性骨髓瘤,白血病,和非小细胞肺癌),与对照组相比抑制生长达50% 时的浓度为0.5 到10μM。Vorinostat作用于淋巴瘤和白血病细胞,包括 Burkitt, B-细胞急性淋巴细胞白血病 (B-ALL), MCL, DLBCL, ATL和T-细胞,不同程度抑制细胞增殖。除了抑制转化细胞增殖, Vorinostat 也抑制正常细胞增殖,通过比较Vorinostat 作用于一组细胞系–正常人非纤维细胞(WI-38)和 SV40巨大T抗原转化WI-38(VA-13细胞)而得到证明。Vorinostat 抑制两种类型细胞增殖,这种作用存在剂量依赖性。但发现Vorinostat 对转化细胞具有选择毒性,包括使肿瘤细胞死亡,而对正常细胞只起抑制作用,不会使其死亡。[1] Genistein 和Vorinostat 联用效果比5-aza和Vorinostat 联用作用于诱导细胞死亡有效很多。Genistein和Vorinostat联用作用于ARCaP-E使增殖降低 80 %,作用于ARCaP-M细胞,增殖降低60 %以上。Genistein和Vorinostat 联用抑制细胞增殖具有协同效应。作用于ARCaP-E 细胞(820个基因 诱导和1046个基因抑制) ARCaP-M 细胞,Vorinostat比Genistein 影响更多基因。[2] Vorinostat作用于肿瘤细胞表面,提高Fas蛋白水平,这种作用存在剂量依赖性,且按0.75 μM剂量处理,提高达到一个稳定水平。[3] Vorinostat 抑制肿瘤细胞生长,包括NB4, H460 和HCT-116,IC50分别为0.7μM, 3.4μM和1.2 μM。[4]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
H1299 MYHLbY5ie2ViQYPzZZk> NV3jSmxpOjBibXnu NXrlOJVGTE2VTx?= MkLqTY5pcWKrdH;yfUBi[3Srdnn0fUBi\2GrboP0JGhFSUNiZX76fY1mKHerdHigTWM2OCCxZjCwMlE6PCEQvF2= NWKwPG0yRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUS1NlE1OjJpPkG0OVIyPDJ{PD;hQi=>
HT1080 MkT0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2CwNlczKGh? MkXmSG1UVw>? MWPJR|UxRTJwNDFOwG0> NYP2OHZrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUKyO|AyPzVpPkGyNlcxOTd3PD;hQi=>
K562 NGGwfY9McW6jc3WgRZN{[Xl? M{Gw[lYhcA>? NULyOoxrTE2VTx?= MYXJcohq[mm2aX;uJI9nKGi3bXHuJIhqe3SxbnWg[IVi[2W2eXzhd4UhMG2reIT1doUhd2ZiSFTBR|Eh[W6mIFjERWMzMSC5aYToJGlEPTBib3[gNE4xOSEQvF2= MnjqQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJ2MUmzPFAoRjF{NEG5N|gxRC:jPh?=
A20 NFjNU2dMcW6jc3WgRZN{[Xl? NWnNfoNIOSCq NWrRT2JnTE2VTx?= NGPxenBidnSrLVjERWMyKGGldHn2bZR6KHerdHigTWM2OCCxZjCwMlEyOiEQvF2= NIrzVpc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUm2NFQ5QSd-MUG5OlA1QDl:L3G+
Friend leukemic cell MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{nwSVUxKM7:TR?= MX63NkBp NFHyeVFFVVOR MnnyTWM2OD1yLkm5JO69VQ>? NYLoSGM4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUKxNFk6OTNpPkGyNVA6QTF|PD;hQi=>
H1299 MnTDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2XTVlczKGh? MXXEUXNQ NVPrc3RkUUN3ME23MlI1KM7:TR?= MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPDV{MUSyNkc,OTR3MkG0NlI9N2F-
HeLa MULLbY5ie2ViQYPzZZk> NEHOfJE{OCCvaX6= NIjISWtKdmirYnn0c5J6KGOxbnPlcpRz[XSrb36gZYdicW6|dDDobZN1d26nIHTlZYNmfHmuYYPlJJdqfGhiSVO1NEBw\iByLkK4JO69VQ>? M4DPeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3NkCzPVQ6Lz5zNU[wN|k1QTxxYU6=
LOX-IMVI M2DRV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnH0OFghcA>? NFzadY1KSzVyPUGuN{DPxE1? M1;mSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{G1OFcxLz5zNUexOVQ4ODxxYU6=
NCI-H226 M1TPSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MY[0PEBp NVvsOIFMUUN3ME2yMlYh|ryP MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTdzNUS3NEc,OTV5MUW0O|A9N2F-
RXF-631L M1e3eWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXPwdHhpPDhiaB?= NHrLVoJKSzVyPUKg{txO MmnCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV5MUW0O|AoRjF3N{G1OFcxRC:jPh?=
SNB-78 M4XJOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1jqR|Q5KGh? MkjsTWM2OD1zNjFOwG0> MmPzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV5MUW0O|AoRjF3N{G1OFcxRC:jPh?=
St-4 NUnWSnVDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIf6[VA1QCCq NXixVFBlUUN3ME21MlIh|ryP M3j4PVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{G1OFcxLz5zNUexOVQ4ODxxYU6=
ARP1 NVfRTpRQTnWwY4Tpc44hSXO|YYm= NV7ZbYhWOiEQvF2= NIHqVVU3KGh? MoLPTY5lfWO2aX;uJI9nKFB{MWfBSlEh\2WwZTDlfJBz\XO|aX;u NVP2NoR3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUS3N|Q5ODZpPkG0O|M1QDB4PD;hQi=>
CEM M3TCdmtqdmG|ZTDBd5NigQ>? M4THV|EhcA>? NUT4V5JUTE2VTx?= M1W4R2lvcGmkaYTpc44hd2ZiSFTBR{B4cXSqIFnDOVAhd2ZiMD6zN{DPxE1? NV3vV|RORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[0NlAxPjRpPkG2OFIxODZ2PD;hQi=>
HCT15 M2TJPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVW0PEBp NV7GRYdnT0l3ME2wMlgzKM7:TR?= MorhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ5MkOyNlcoRjF4N{KzNlI4RC:jPh?=
NCI-H23 M1\6d2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXe0PEBp M2rqNWdKPTB;MD65NkDPxE1? NW\oN2VvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[3NlMzOjdpPkG2O|I{OjJ5PD;hQi=>
GM15850 MnL2T4lv[XOnIFHzd4F6 MVOyMlUh|ryP NYL3SXA{QTZiaB?= M1K4bWROW09? NHPQOnFKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gbIl{fG:wZTDIN{BtgXOrbnWgNVQh[WOndInsZZRqd25ib3[gSnhPKGenbnW= M37Y[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4OUKxN|Y4Lz5zNkmyNVM3PzxxYU6=
GM15850 MVzLbY5ie2ViQYPzZZk> M1[2TFIvPSEQvF2= MlL3PVYhcA>? MX;EUXNQ MlLmTY5pcWKrdHnvckBw\iCKRFHDJIF{e2W|c3XkJIF{KGmwY4LlZZNmKGmwIHjpd5RwdmViSESgcJl{cW6nIEWgZYNmfHmuYYTpc44hd2ZiRmjOJIdmdmV? M3KyflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4OUKxN|Y4Lz5zNkmyNVM3PzxxYU6=
GM15850 M3nKZ2tqdmG|ZTDBd5NigQ>? NGnaTYEzNjVizszN Mkn5PVYhcA>? NIHoZ2lFVVOR MmXNTY5pcWKrdHnvckBw\iCKRFHDJIF{e2W|c3XkJIF{KGmwY4LlZZNmKGmwIHjpd5RwdmViSESgcJl{cW6nIEGyJIFk\XS7bHH0bY9vKG:oIF\YUkBo\W6n MkXDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ7MkGzOlcoRjF4OUKxN|Y4RC:jPh?=
GM15850 MUjLbY5ie2ViQYPzZZk> M{jMb|IvPSEQvF2= NWrTTFA5QTZiaB?= NUnUO2Z[TE2VTx?= NVfRT2NXUW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJIhqe3SxbnWgTFMhdHm|aX7lJFkh[WOndInsZZRqd25ib3[gSnhPKGenbnW= M2\Db|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4OUKxN|Y4Lz5zNkmyNVM3PzxxYU6=
GM15850 NE\HOpdMcW6jc3WgRZN{[Xl? NEX0fnQzNjVizszN MXO5OkBp NFHwbnZFVVOR NILQNFhKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gbIl{fG:wZTDIOEBtgXOrbnWgPEBi[2W2eXzheIlwdiCxZjDGXG4h\2WwZR?= M2S5NVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4OUKxN|Y4Lz5zNkmyNVM3PzxxYU6=
GM15850 NULGdW9FU2mwYYPlJGF{e2G7 MYKyMlUh|ryP MX[5OkBp M2HLU2ROW09? M3roNmlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDobZN1d26nIFi0JIx6e2mwZTCxOkBi[2W2eXzheIlwdiCxZjDGXG4h\2WwZR?= M4T2OFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4OUKxN|Y4Lz5zNkmyNVM3PzxxYU6=
U937 NUTkUpBTTnWwY4Tpc44hSXO|YYm= NYHEUYlpPSEQvF2= NWnxZpVHOjRiaB?= M4jtcGROW09? MnPmR4VtdCCleXPs[UBienKnc4SgZpkh[WOldX31cIF1cW:wIHH0JHMwTzJxTTDwbIF{\Q>? MmnZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdyMES3NVgoRjF5MEC0O|E5RC:jPh?=
H661 M4i2PWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV3GU2NqPDhiaB?= MnfBTWM2OD1zIN88US=> NGXPPGo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{G1O|AxQSd-MUexOVcxODl:L3G+
U937 M4n0W2Z2dmO2aX;uJGF{e2G7 MXu1JO69VQ>? MoH6NlQhcA>? MnzwSG1UVw>? NXXBeWxmUW6lcnXhd4UhcW5iaHnzeI9v\SCKMzDhZ4V1gWyjdHnvci=> M3XoSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NES3O|UxLz5zN{S0O|c2ODxxYU6=
U937 MUXGeY5kfGmxbjDBd5NigQ>? M4f0SlEh|ryP NWDNV4NxOjRiaB?= NG\ISo1FVVOR MXXF[oZm[3Rib36gZYxxcGFidIXieYxqdiCjY3X0fYxifGmxbh?= NXnLfnpZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0OFc4PTBpPkG3OFQ4PzVyPD;hQi=>
RAW264.7 MUnGeY5kfGmxbjDBd5NigQ>? M{nRXVExKM7:TR?= Ml\sNlRp Mn3Ve4F1\XJ? M{mwZWlvcGmkaYTpc44hd2ZiTGDTMZN1cW23bHH0[YQhXE6IYXzwbIEheHKxZIXjeIlwdiC5aYToJGlEPTBib3[gNE44PiEQvF2= Mnf3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2N{e1NVgoRjF5NEe3OVE5RC:jPh?=
RAW264.7 M3;uZ2Z2dmO2aX;uJGF{e2G7 NVLF[XIxOTBizszN NHX2XFEzPGh? M1z3fpdifGW{ MlSyTY5pcWKrdHnvckBw\iCOUGOtd5RqdXWuYYTl[EBPVyCycn;keYN1cW:wIIfpeIghUUN3MDDv[kAyNjh6IN88US=> NUjCcmpJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0O|c2OThpPkG3OFc4PTF6PD;hQi=>
SC9 M2HQSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn33OFghcA>? MWPJR|UxRTBwNkC2JO69VQ>? M4XJSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUC3NlE6Lz5zN{WwO|IyQTxxYU6=
ST14A MYfGeY5kfGmxbjDBd5NigQ>? M1PxRlUhdk1? M3j0XVczKGh? MlrPTY5kemWjc3WgbY4hWkWVVD;OVnNHKG2UTlGg[ZhxemW|c3nvci=> MnXiQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NkW5PVMoRjF5NU[1PVk{RC:jPh?=
ST14A NX;TUJk6TnWwY4Tpc44hSXO|YYm= MlPnOUBvVQ>? NGD4TXk4OiCq MYLJcoNz\WG|ZTDpckBGOkZzIH3SUmEh\XiycnXzd4lwdg>? NUXBNlRyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe1OlU6QTNpPkG3OVY2QTl|PD;hQi=>
PANC1 NHnnNJhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmT3NUDPxE1? MYHJR|UxRTBwNEWg{txO M17oVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUi4O|Q1Lz5zN{W4PFc1PDxxYU6=
PANC1 M{G0S2Z2dmO2aX;uJGF{e2G7 NWXLWYs5OSEQvF2= NU\ye4JuOjRiaB?= NYrDZoJkUW6lcnXhd4UhcW5icEKxW2FHOS:FSWCxJIdmdmViZYjwdoV{e2mxbh?= NFH5ZW49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{W4PFc1PCd-MUe1PFg4PDR:L3G+
PANC1 MnjQSpVv[3Srb36gRZN{[Xl? NEHBfJgyKM7:TR?= NInnfYUzPCCq NYnJcYZtUW6lcnXhd4UhcW5icEK3b4lxOSCpZX7lJIV5eHKnc4Ppc44> MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzV6OEe0OEc,OTd3OEi3OFQ9N2F-
PT45 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MU\JR|UxRTRizszN NIL6OI49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{W4PFc1PCd-MUe1PFg4PDR:L3G+
ACHN MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYqyNUBp M{jHdWdKPTB;MD62OUDPxE1? NUDa[25iRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2OlI3ODZpPkG3OlYzPjB4PD;hQi=>
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DU145 NGCzZ|FMcW6jc3WgRZN{[Xl? MUKyMlUh|ryP NXv2d5JoOjRiaB?= NVe5fnIzTE2VTx?= M2T1eWlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyC3cILl[5Vt[XSrb36gc4YheDJzd3HmNUBxem:2ZXnuJIV5eHKnc4Ppc44> M4HKN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{Mk[wNVY3Lz5{MkK2NFE3PjxxYU6=
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DU145 NFzzUJRMcW6jc3WgRZN{[Xl? NXTaRYJiPSEQvF2= NIrwPYEzPCCq NU\pcHRFTE2VTx?= NFHH[odKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaHnzeI9v\SCKMzDofZBmemGlZYT5cIF1cW:w NVvUbYxHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKyOlAyPjZpPkKyNlYxOTZ4PD;hQi=>
786-0 NYDWcJFbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEHET|c3NjJizszN MYm3NkBp NIHJN4RFVVOR MXrHTVUxRTNwMjFOwG0> NIPzfIg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
A498 NHjYeYJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYC2MlIh|ryP NIexZnc4OiCq MX3EUXNQ NXnEbJp4T0l3ME2xMlYh|ryP M1fPc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
A549/ATCC NVTGfXFUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1vtOVYvOiEQvF2= M3z2eVczKGh? MljLSG1UVw>? NGnyW5JIUTVyPUGuOkDPxE1? MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
ACHN MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGPiWm03NjJizszN M2rpPVczKGh? NUX5W2YyTE2VTx?= MnS2S2k2OD1zLkOg{txO NVXyemtiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
BT549 Mn;ZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGjYXmo3NjJizszN MX[3NkBp MVnEUXNQ MlzxS2k2OD1zLkOg{txO NWjie5Q3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
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HCT15 M3;DNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXH1eZR[Pi5{IN88US=> M1XaU|czKGh? MnvISG1UVw>? NV3pbXJTT0l3ME2yMlUh|ryP MmrYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
HOP92 MlPwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn3pOk4zKM7:TR?= M3vtT|czKGh? MoTpSG1UVw>? M1vOXGdKPTB;NDFOwG0> NHTMWJo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
IGROV1 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX22MlIh|ryP MVS3NkBp MVfEUXNQ NH3QNnBIUTVyPUGuN{DPxE1? MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
LOXIMVI MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX73SpFYPi5{IN88US=> MYG3NkBp M{Oxd2ROW09? MV;HTVUxRTFizszN NHzFS5g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
M14 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXLOWYp[Pi5{IN88US=> NVPUd5dPPzJiaB?= M{npNmROW09? M3P2dWdKPTB;MT6zJO69VQ>? NYDMe2ViRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
MALME-3M MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWi2MlIh|ryP M2LzR|czKGh? Moq4SG1UVw>? M1eydGdKPTB;MD6zNkDPxE1? NX;OO2JkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
MCF10A MmPlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlOwOk4zKM7:TR?= NGjJdpk1QCCq NEnTW3ZFVVOR NYTPR4dbT0l3ME25MlYh|ryP NGXk[ms9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
MDA-MB-435 NWS4PZNrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVS2MlIh|ryP M4HodFczKGh? MlPBSG1UVw>? Mme4S2k2OD1yLkWg{txO M{fPflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
MDA-MB-468 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MU[2MlIh|ryP Mk\BO|IhcA>? M{myU2ROW09? MVzHTVUxRTBwNkOg{txO MnPmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
MOLT4 M1LUbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIPp[os3NjJizszN NUfXfVZ{PzJiaB?= M{XZ[WROW09? M{TFRmdKPTB;MD60JO69VQ>? MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
NCI-ADR-RES NV;uWm45T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX7WN2JYPi5{IN88US=> NGHJc2Q4OiCq MVXEUXNQ MXjHTVUxRTBwMU[g{txO MkDFQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
NCI-H23 NXm0ZmZnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3rsb|YvOiEQvF2= MoDUO|IhcA>? NXP3O|FmTE2VTx?= NVvpNIhjT0l3ME2xJO69VQ>? MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
NCI-H322M MonlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1\UWVYvOiEQvF2= NILhWXc4OiCq NU\K[XBtTE2VTx?= NWT1VFJ7T0l3ME2wMlc6KM7:TR?= MofSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
NCI-H460 M{nvNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGfJNZI3NjJizszN NEPkcZM4OiCq NGnrXGNFVVOR MnzTS2k2OD1yLke5JO69VQ>? MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
NCI-H522 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MorYOk4zKM7:TR?= NFW4OXE4OiCq MUPEUXNQ NH74U|JIUTVyPUCuOUDPxE1? MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
OVCAR3 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWC2MlIh|ryP NHXuSG04OiCq MlPnSG1UVw>? MXvHTVUxRTFwMzFOwG0> MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
OVCAR4 NXPaVZlPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX[2MlIh|ryP MWi3NkBp MnvHSG1UVw>? MkH6S2k2OD12IN88US=> Ml7aQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
OVCAR5 NHfwO|JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnrVOk4zKM7:TR?= NXvxV3pLPzJiaB?= NEnmPVNFVVOR MXHHTVUxRTBwN{mg{txO M3XF[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
OVCAR8 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHnRVlc3NjJizszN NXfTNXpkPzJiaB?= M4jEOmROW09? NYK2[nR4T0l3ME2wMlUh|ryP M{jTdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
RXF393 NVTkdXdnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2\NOlYvOiEQvF2= M4exb|czKGh? NWPVNlhPTE2VTx?= NEH6cWFIUTVyPUGuN{DPxE1? MlrpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
SF268 NYfXRldJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlrCOk4zKM7:TR?= MmnOO|IhcA>? MVzEUXNQ MmfoS2k2OD1zLk[g{txO NWrYVnlqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
SF295 M2jpTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF7zeIk3NjJizszN MUK3NkBp M4C2S2ROW09? NEnRfmlIUTVyPUGuOkDPxE1? NGr3[pA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
SF539 M3XkdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIC2Wo03NjJizszN NUjjVo84PzJiaB?= M2fJWmROW09? MnnlS2k2OD1{IN88US=> M{P3W|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
SK-MEL-2 NYSzO4xqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3jTR|YvOiEQvF2= M1Hre|czKGh? M{jCc2ROW09? NVzZOVRbT0l3ME2xMlMh|ryP NGf4XlE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
SK-MEL-28 NU\yfnZwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2DxWFYvOiEQvF2= NHnaR484OiCq M2PhUmROW09? NGTkT3dIUTVyPUGg{txO M1XDWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
SK-MEL-5 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmPqOk4zKM7:TR?= MVi3NkBp Mn7xSG1UVw>? MkHpS2k2OD1yLk[zJO69VQ>? NYDkNpFwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
SKOV3 M2nQRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEG5Wm43NjJizszN NV\UR3hGPzJiaB?= NWnuRZI1TE2VTx?= MV;HTVUxRTFizszN NHnnZ|c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
SN12C NH\GS3JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2PK[|YvOiEQvF2= MmXrO|IhcA>? M2i5[2ROW09? NUHxZXRoT0l3ME2yJO69VQ>? M4LHUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
SNB19 Mo\KS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MY[2MlIh|ryP M3HLd|czKGh? NUDoRVlOTE2VTx?= NEL3RpFIUTVyPUCuOlMh|ryP MkL3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
SNB75 NVLBUpR2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIKweno3NjJizszN MVy3NkBp NVfZbHdrTE2VTx?= M3zMdGdKPTB;MD63PUDPxE1? M4D5PVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
SR MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEXTbGE3NjJizszN NU[xc3Q2PzJiaB?= NYn1OItETE2VTx?= M2SzZmdKPTB;MD60JO69VQ>? MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
T47D MmnxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVu2MlIh|ryP NIfuZ4g4OiCq M4PuSWROW09? NFnKPFVIUTVyPUCuOUDPxE1? NUjyfZdoRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
TK10 M{PE[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M37CbVYvOiEQvF2= M2LEXlczKGh? NWnxTFRxTE2VTx?= NES3[pZIUTVyPUCuOlMh|ryP M3X0SVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
UACC257 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVLQVVFvPi5{IN88US=> NVm2UmlMPzJiaB?= NHvkRnNFVVOR MkTkS2k2OD1yLkWg{txO NFuzVGs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
UACC62 NX3ZVWhbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2\2OFYvOiEQvF2= M{DZdVczKGh? NEDhb2hFVVOR M4T2eGdKPTB;MD60JO69VQ>? MmjtQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
UO31 NGLMS2NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXy2MlIh|ryP NUL2eYFwPzJiaB?= M2myfWROW09? NXmyeWxJT0l3ME2wMlUh|ryP NHTaO|U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
Hep3B NHviTldIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MojxOFghcA>? M{i4UGROW09? MWXHTVUxRTBwNkmg{txO NV;6OXZzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|k5PjNpPkKyOFM6QDZ|PD;hQi=>
BE(2)-C MmfrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGnJSGw4OiCq MVjEUXNQ MVfJR|cxRTJizszN M4K3cVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OUOyN|E3Lz5{MkmzNlMyPjxxYU6=
Bel7402 NVS5TGJKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEDVelU4OiCq MXfEUXNQ MmTXS2k6OD1zNzFOwG0> NWWyfpJLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwOlE{PzZpPkKzNFYyOzd4PD;hQi=>
Bel7404 MlTTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NITx[ng4OiCq MmDvSG1UVw>? NH\6T3pIUTlyPUG4JO69VQ>? M4\OfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|ME[xN|c3Lz5{M{C2NVM4PjxxYU6=
BGC823 M2\BUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWPPV41GPzJiaB?= NFPmUlNFVVOR NVzrOG01T0l7ME23MlUh|ryP MojSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNyNkGzO|YoRjJ|ME[xN|c3RC:jPh?=
MGC803 MonsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWm3NkBp NWT2ToY2TE2VTx?= MkexS2k6OD1zMD64JO69VQ>? NV60SpZIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwOlE{PzZpPkKzNFYyOzd4PD;hQi=>
SGC7901 M{jPZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkniO|IhcA>? NFLIe5NFVVOR NEftSXdIUTlyPUmuOEDPxE1? NUPoRpptRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwOlE{PzZpPkKzNFYyOzd4PD;hQi=>
SKHEP1 MmrhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHPuUok4OiCq NWPJZ2loTE2VTx?= NW\NV|BjT0l7ME2xO{DPxE1? NVu0fXhJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwOlE{PzZpPkKzNFYyOzd4PD;hQi=>
SMMC7721 NXviW45kT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NInvOYw4OiCq NWXHdYNSTE2VTx?= NF\IWXRIUTlyPUKwJO69VQ>? M2DFclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|ME[xN|c3Lz5{M{C2NVM4PjxxYU6=
NUGC3 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1jhXlExKM7:TR?= NV\vSI5qT0l;Mj65OEDPxE1? MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzF4M{OzNkc,OjNzNkOzN|I9N2F-
A2780 CisR MXPLbY5ie2ViQYPzZZk> NYDQXG96OThiaB?= MojyTY5pcWKrdHnvckBw\iCKRFHDJJdqfGhiSVO1NEBw\iByLkS0JO69VQ>? M2TXV|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MkWyOlA{Lz5{M{K1NlYxOzxxYU6=
CAL27 sens M{XqWGtqdmG|ZTDBd5NigQ>? MVKxPEBp M2rkRWlvcGmkaYTpc44hd2ZiSFTBR{B4cXSqIFnDOVAhd2ZiMD6zOkDPxE1? Mo\5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN{NUK2NFMoRjJ|MkWyOlA{RC:jPh?=
CAL27 CisR MmjOT4lv[XOnIFHzd4F6 MVexPEBp MUTJcohq[mm2aX;uJI9nKEiGQVOge4l1cCCLQ{WwJI9nKDBwNkGg{txO NWfCe|lZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyOVI3ODNpPkKzNlUzPjB|PD;hQi=>
KYSE-510 CisR MkC0T4lv[XOnIFHzd4F6 MmLhNVghcA>? MoTiTY5pcWKrdHnvckBw\iCKRFHDJJdqfGhiSVO1NEBw\iByLkW5JO69VQ>? NHTwNHc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{K1NlYxOyd-MkOyOVI3ODN:L3G+
KYSE-510 sens Mlr4T4lv[XOnIFHzd4F6 NYrzNZZ[OThiaB?= M132XGlvcGmkaYTpc44hd2ZiSFTBR{B4cXSqIFnDOVAhd2ZiMD63JO69VQ>? M2fpOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MkWyOlA{Lz5{M{K1NlYxOzxxYU6=
MDA-MB-231 sens MVHLbY5ie2ViQYPzZZk> NVPodlJ1OThiaB?= M2HuU2lvcGmkaYTpc44hd2ZiSFTBR{B4cXSqIFnDOVAhd2ZiMD62NUDPxE1? MknXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN{NUK2NFMoRjJ|MkWyOlA{RC:jPh?=
MDA-MB-231 CisR NUnpT4ZqU2mwYYPlJGF{e2G7 MUexPEBp NUPMbXR2UW6qaXLpeIlwdiCxZjDISGFEKHerdHigTWM2OCCxZjCwMlYyKM7:TR?= NVywTnB4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyOVI3ODNpPkKzNlUzPjB|PD;hQi=>
ES2 NXz6ZmRST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHnXNpg1QCCq MUPEUXNQ NFLZ[YhKSzVyPUGyMlch|ryP NWnlTIVLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO0PVM1PDlpPkKzOFk{PDR7PD;hQi=>
MDA-MB-231 M{fIdmtqdmG|ZTDBd5NigQ>? MXqxNEDPxE1? MmrsN|AhdWmw MlyySG1UVw>? MoK5TY5pcWKrdHnvckBw\iCKRFHDNoE> MlH1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN2OUO0OFkoRjJ|NEmzOFQ6RC:jPh?=
MDA-MB-231 M3rKd2tqdmG|ZTDBd5NigQ>? MmL1NUDPxE1? NXjSe5h5OjRiaB?= NWT5OpY4TE2VTx?= NYTQVnN2UW6qaXLpeIlwdiCxZjDISGFEPiCjc4Pld5Nm\CCjczDhZ4V1gWyjdHnvckBt\X[nbIOgc4YhfHWkdXzpci=> M2fLeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NEmzOFQ6Lz5{M{S5N|Q1QTxxYU6=
HS68 MX3DfZRwfG:6aXOgRZN{[Xl? MoPXNVAh|ryP Mn7jO|IhcA>? MkDXSG1UVw>? NI\IXW5KSzVyPUSuOkDPxE1? MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzV5MEW0Nkc,OjN3N{C1OFI9N2F-
MEF M4\OSWN6fG:2b4jpZ{BCe3OjeR?= M1nlNFExKM7:TR?= NV75e5dXPzJiaB?= NX\rbVJMTE2VTx?= Mn\uTWM2OD12LkSg{txO MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzV5MEW0Nkc,OjN3N{C1OFI9N2F-
BGC823 M2qzXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVntd5B6TE2VTx?= M2TFRmdKPTB;Mz6wPUDPxE1? MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzZyMUewOkc,OjN4MEG3NFY9N2F-
High5 NV3kO4MxU2mwYYPlJGF{e2G7 NUfSSZBqOjRiaB?= NV\iSFl4UW6qaXLpeIlwdiCxZjDoeY1idiC{ZXPvcYJqdmGwdDDISGFEPiC5aYToJGlEPTBib3[gNE4xQSEQvF2= MkKwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4MEK1NlMoRjJ|NkCyOVI{RC:jPh?=
High5 MVHLbY5ie2ViQYPzZZk> MlPWNlQhcA>? MnK2TY5pcWKrdHnvckBw\iCqdX3hckBz\WOxbXLpcoFvfCCKRFHDNUB4cXSqIFnDOVAhd2ZiMD6xNkDPxE1? NYKzeXlyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2NFI2OjNpPkKzOlAzPTJ|PD;hQi=>
High5 MmrPT4lv[XOnIFHzd4F6 NIntOHYzPCCq M2fId2lvcGmkaYTpc44hd2ZiaIXtZY4hemWlb33ibY5idnRiSFTBR|Mhf2m2aDDJR|UxKG:oIECuNVch|ryP MoPUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4MEK1NlMoRjJ|NkCyOVI{RC:jPh?=
A549 NGDNb|FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NICwVnJFVVOR NFe0SFNKSzVyPUGuNFc6KM7:TR?= MkD0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4NESyNVAoRjJ|NkS0NlExRC:jPh?=
HCT116 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXLiNnFrTE2VTx?= M1XieGlEPTB;MD63OVch|ryP NFL2[IE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{[0OFIyOCd-MkO2OFQzOTB:L3G+
K562 Mk\HS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn7OSG1UVw>? MV;JR|UxRTBwNkS1JO69VQ>? NGjvVHY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{[0OFIyOCd-MkO2OFQzOTB:L3G+
GBC-SD MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFjF[Zk2KM7:TR?= MWK3NkBp M2XXTWROW09? NYnibZl2UUN3ME2xOE45KM7:TR?= M2i2WVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|N{C3NlYxLz5{M{ewO|I3ODxxYU6=
HGC27 MmDWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXPUV29DPSEQvF2= MWq3NkBp NWniZWtMTE2VTx?= NHmzOIRKSzVyPUWuOEDPxE1? NHvoOXI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{ewO|I3OCd-MkO3NFczPjB:L3G+
HL60 MnTXT4lv[XOnIFHzd4F6 MXS1JO69VQ>? Ml70NlQhcA>? MXrEUXNQ M1jve2lvcGmkaYTpc44hd2ZiSFTBRy=> MoizQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN5MEeyOlAoRjJ|N{C3NlYxRC:jPh?=
Vero M{iyO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV:3NkBp MnPkSG1UVw>? MXfJR|UxRTBwOTFOwG0> NGTMbWo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{e4OlQ2Oid-MkO3PFY1PTJ:L3G+
NCI60 MmG4R5l1d3SxeHnjJGF{e2G7 NHuwbpg1QCCq MX3EUXNQ NHHXTnRIUT1yLkWzJO69VQ>? NHuzTZg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NECxOVMzPyd-MkSwNVU{Ojd:L3G+
SW620 NXz4WFZOS3m2b4TvfIlkKEG|c3H5 MYG0PEBp MXvEUXNQ MVnHTV0xNjV2IN88US=> Mo[zQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyMUWzNlcoRjJ2MEG1N|I4RC:jPh?=
U251 M4PUbGN6fG:2b4jpZ{BCe3OjeR?= M2\jTVQ5KGh? MnfsSG1UVw>? M1LGTWdKRTFwNUOg{txO NH;hR2I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NECxOVMzPyd-MkSwNVU{Ojd:L3G+
KM12 MWrDfZRwfG:6aXOgRZN{[Xl? M{TBZlQ5KGh? M3L1VmROW09? NXew[JBsT0l;MT64PEDPxE1? M1f1V|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MEG1N|I4Lz5{NECxOVMzPzxxYU6=
Hs578T MUfDfZRwfG:6aXOgRZN{[Xl? MVe0PEBp MmTTSG1UVw>? NEHmbI1IUT12LkizJO69VQ>? NFHETI89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NECxOVMzPyd-MkSwNVU{Ojd:L3G+
MDA-MB-231 M{nBZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoPVOFghcA>? NIXlXllKSzVyPUCuNVYh|ryP MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDB7NUCxOkc,OjRyOUWwNVY9N2F-
MCF7 NG\ReYhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFn2cIE1QCCq NFjIenFIUT1yLkS1JO69VQ>? M1fYTlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MUG5OVU2Lz5{NEGxPVU2PTxxYU6=
MDA-MB-435 M1vkUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{m2UlQ5KGh? NIiwZotIUT1yLki4JO69VQ>? MlvDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRzMUm1OVUoRjJ2MUG5OVU2RC:jPh?=
AsPC1 NHTybVdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVraVHg1OzBizszN NFPRTnM1QCCq NYDJe25TTE2VTx?= M2K5XGlEPTB;Mz62OkDPxE1? MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDF6NUO3PEc,OjRzOEWzO|g9N2F-
Jurkat E6.1 NED2VGhMcW6jc3WgRZN{[Xl? NVvwO3dPOiCq MmXESG1UVw>? MoLkTY5pcWKrdHnvckBw\iCKRFHDOEB4cXSqIFnDOVAhd2ZiMD6wOEDPxE1? NHf5boM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEK2NVg3Oid-MkSyOlE5PjJ:L3G+
KG1 MnHTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NELNTJU1QCCq MUfJR|UxRTFwMUWg{txO MoHGQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR3MkWwNFMoRjJ2NUK1NFA{RC:jPh?=
HEL Mm\PS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1G3WlQ5KGh? NIO0[ldFVVOR NUGxdIdCUUN3ME2wMlQ6KM7:TR?= Mkn4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR4OUSwOVUoRjJ2Nkm0NFU2RC:jPh?=
HSC3 M3r1[2N6fG:2b4jpZ{BCe3OjeR?= Mln1NVIhcA>? MVLEUXNQ M1u0SWlEPTB;MD63NUDPxE1? MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDd4NkW2NEc,OjR5Nk[1OlA9N2F-
HT-29 MVPDfZRwfG:6aXOgRZN{[Xl? MYqxNkBp M{X2b2ROW09? MYPJR|UxRTBwN{Kg{txO NUf1NmI4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3OlY2PjBpPkK0O|Y3PTZyPD;hQi=>
KB NX\TO4VHS3m2b4TvfIlkKEG|c3H5 MUSxNkBp NIPrbo5FVVOR NXH1[2FyUUN3ME2wMlc2KM7:TR?= NXTHO4tKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3OlY2PjBpPkK0O|Y3PTZyPD;hQi=>
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