Vorinostat (SAHA, MK0683)

目录号：S1047 别名： SAHA, MK0683, suberoylanilide hydroxamic acid

Vorinostat (SAHA, MK0683) Chemical Structure

Molecular Weight(MW): 264.3

Vorinostat (suberoylanilide hydroxamic acid, SAHA)是一种HDAC抑制剂，无细胞试验中IC50为~10 nM。

规格 价格 库存 购买数量  
RMB 1558.77 现货
RMB 1198.15 现货
RMB 1794.86 现货
有超大折扣
大剂量询单有大折扣！

今日订购，明日送达，全国免运费！

全国免费电话：400-668-6834   |   Email：info@selleck.cn

客户购买Selleck的此次产品后发表的文献100篇：

客户使用该产品的20个实验数据：

  • Activity of vorinostat in Jurkat and Peer T-ALL cell lines in an MTT cell viability assay. Cells were treated with increasing drug concentrations for 72 h. The data are plotted as the mean % of DMSO-treated control cells against the corresponding drug concentration. The error bars are the standard error. For each drug and cell line, 3-4 independent experiments were performed with 6 replicates at each drug concentration.

    Nature 2011 471, 235-9. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Differential effects of HDAC inhibitors on histone and tubulin acetylation. Immunofluorescence analysis of histone H3 (K9ac/K14ac) and tubulin acetylation in HeLa cells treated for 4 h with vehicle, SAHA (10 μM), tacedinaline (50 μM), PCI-24781 (20 μM. (a) Mapping of histone acetylation in K562 cells treated with HDAC inhibitors by LC-MS/MS. Cells were treated with TSA (10 μM), SAHA (5 μM), PCI-24781 (2 μM), tacedinaline (50 μM) for 6 h. Histones were extracted from cells and acetylated peptides were quantified after isobaric tagging.

    Nat Biotechnol 2011 29, 255-265. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • Western blot analysis of histone H3 acetylation in the spleen of untreated and vorinostat-treated hNF-E2 tg mice (n = 4 of each genotype).

    J Exp Med 2012 209, 35-50. Vorinostat (SAHA, MK0683) purchased from Selleck.

    SAHA down-regulates c-FLIP expression and increases the sensitivity of CaP cells to undergo apoptosis in the presence of bicalutamide (A) Bar graph illustrating the sub-G0/G1 cell population in 22Rv1 (left panel) and LNCaP (right panel) cells in the absence and presence of 10μM bicalutamide, administered as a single agent or in ombination with increasing concentrations of the HDAC inhibitor, SAHA. (B) Immunoblots demonstrating the single agent activity of bicalutamide or SAHA, or effect upon their combined administration on the expression of c-FLIP and/or the processing of PARP. Equal protein loading was confirmed by GAPDH. (C) Bar graph illustrating the effect of bicalutamide and SAHA upon the induction of caspase-8 or caspase-3/7 activity in 22Rv1 cells (left panel) and LNCaP cells (right panel). (D) Immunoblots characterizing the impact of SAHA and/or bicalutamide upon the induction of PARP cleavage, in the absence or presence of the pan-caspase inhibitor, ZIETD. ZIETD was incubated with the cells for 12 h prior to the experiment. All data points shown in (A) and (C) represent the mean ± S.E.M. value, calculated from four independent experiments.

    Clin Cancer Res 2012 18, 3822-33. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • Analyses of efficacy, potency and IC50 of HDAC inhibitors point toward HDACs 1–3 as relevant candidates for beta cell protection. Ranking and raw data on ITF drugs (Table 3) and commercial HDAC inhibitors (Table 4) underlying the heat maps of Fig. 1 (A and B). The HDAC inhibitor compounds were tested using a HDAC activity kit and recombinant proteins to determine IC50 values on each individual HDAC (right part of the table). Each drug was further tested using Real-Time Cell Analysis (RTCA) to score their maximal effective concentration (ECmax) as well as the corresponding rescue percentage of cytokine treated INS-1 cells. The drugs were ranked according to % rescue. * DMSO alone controls were included in each experiment, but not shown here. The results indicate that the highest concentrations of DMSO used here (1:1,000) were slightly potentiating the proliferation of the cells. The effects observed in this group of compounds were ascribed to the DMSO.?

    Diabetologia 2012 55, 2421-2431. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Suberoylanilide hydroxyamic acid (SAHA) preserves CFP (+) expression in mouse optic nerves (MONs) from older mice. (a) CFP (+) mitochondria were longer and thicker in MONs from 12-month-old Thy-1 CFP mice (inset; scale bar = 2 μm). Oxygen–glucose deprivation (OGD) consistently reduced CFP pixel intensity in 12-month-old MONs despite longer and brighter CFP ( +) mitochondria (yellow arrows). (b) Blockade of AMPA/kain ate receptors with NBQX (30 μM), or pan-Histone deacetylase (HDAC) inhibition with SAHA (5 μM), effectively preserved CFP pixel intensity during OGD. The preservation of CFP (+) mitochondria correlates with protection of the CAP area during OGD and profound recovery.

    J Neurochem 2012 123 Suppl 2, 108-15. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • D and E, Regression of IL-13Ra 2-negative pancreatic tumors treated with SAHA and/or IL-13-PE. Mice were treated daily with i.p. injection of SAHA (25 mg/kg) from day 4 after tumor implantation for two weeks followed by i.t. injection of IL-13-PE (100 μ g/kg) from day 5 for two weeks. F and G, Regression of IL-13Ra 2-posotive pancreatic tumors (HS766T and MIA-PaCa2) treated with SAHA and/or IL-13-PE. The schedule of treatment was similar as in panel D and E. Statistical significances are shown by *: P < 0.05,†: P < 0.001.

    J Transl Med 2011 9, 37. Vorinostat (SAHA, MK0683) purchased from Selleck.

    IL-13Rα2 expression is upregulated in pancreatic tumors but not in organs of mice after treatment with HDAC inhibi tor, SAHA. A, qRT-PCR of human IL-13Rα2 in implanted pancreatic tumors after SAHA and IL-13-PE treatment. Tumors were harvested next day after IL-13-PE treatment and total RNA extracted. Data shown is ratio of human IL-13Rα2/β-actin expression and multiplied by 1000 for convenience. Bars , SD of triplicate determinations. B, qRT-PCR of mouse IL-13Rα2 in mice organs after SAHA and IL-13-PE treatment. Tissues were harvested at the same time point as in panel A and total RNA extracted. Data shown is ratio of mouse IL-13Rα2/β-actin expression and multiplied by 100 for convenience. C, IHC of human IL-13Rα2 in implanted pancreatic tumors after SAHA and IL-13-PE treatment. D, IHC of mouse IL-13Rα2 in mice organs after SAHA and IL-13-PE treatment. Liver, brain, kidney, pancreas, lung and spleen were fixed for immunostaining of mouse IL-13Rα2 as visualized by Alexa555. Nucleus was counterstained by DAPI.

    J Transl Med 2011 9, 37. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • Proliferation o f HT29 and HCT116 cells after 48 h of butyrate or SAHA treatment. Proliferation measurements using the xCEL Ligence RTCA DP instrument (Roche) in cells treated with increasing doses of butyrate or SAHA, compared with control medium cells (0) (*P < 0.05). The mean ?SEM of three cell culture replicates is shown.

    Mol Carcinog 2012 52, 459-74. Vorinostat (SAHA, MK0683) purchased from Selleck.

    SAHA induces the down-regulation of cFLIP expression and promotes TRAIL-mediated activation of a mitochondrial-operated apoptotic pathway. a BT-474 cells were treated as indicated in Fig. 1 and the cells were then harvested to analyse caspase-8, Bid, caspase-9, caspase-3 and PARP expression, using GAPDH as the protein loading control. b BT-474 cells were treated with SAHA for 8 h at the doses indicated and subsequently, the cells were harvested and the apoptosis-related proteins were analysed in western blots as described in the "Materials and Methods". The results shown are representative of at least three independent experiments

    Invest New Drugs 2012 30, 541-547. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • Treatment with SAHA sensitizes breast cancer cells to TRAILinduced apoptosis. BT-474 and MDA-MB-231 cells were incubated for 8 h with SAHA at the doses indicated. After this time, TRAIL (500 ng/ml) was added to some of the cultures for an additional 15 h. Apoptosis was measured as the percentage of cells with subG1 DNA content as described in the "Materials and methods". The results show the mean and S.E.M. of three independent experiments

    Invest New Drugs 2012 30, 541-547. Vorinostat (SAHA, MK0683) purchased from Selleck.

    SAHA facilitates the Itch/AIP4-independent proteasomal degradation of cFLIP proteins in breast cancer cells. a BT-474 cells were treated with SAHA (5 μM) for 8 h in the presence or absence of the proteasome inhibitors MG132 or epoxomicin (at the doses indicated), and they were then harvested and the cFLIP content was analysed in western blots. b BT-474 cells were transfected with either the siRNA oligonucleotides targeting Itch/AIP4 or the non-targeting RNA oligonucleotide (scrambled) for 48 h as described in the "Materials and Methods". Subsequently, the cells were treated with SAHA (5 μM) for 8 h and then cFLIP and Itch/AIP4 expression was analysed in immunoblots

    Invest New Drugs 2012 30, 541-547. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • cFLIP down-regulation following SAHA treatment is responsible for the sensitization of breast cancer cells to TRAIL. a BT-474 cells were transfected with either different siRNAs directed against the cFLIP isoforms or the non-targeting RNA oligonucleotide (scrambled) as described in the "Materials and Methods". After 24 h, the cells were treated with TRAIL (500 ng/ml) for a further 15 h and apoptosis was then measured as the percentage of cells with subG1 DNA content. The results show the mean and S.E.M. of three independent experiments. To verify protein knockdown, cells were harvested 24 h after transfection and the cFLIP levels were assessed in immunoblots. b. BT-474 cells overexpressing Cflipl (pBABE-FLIPL) or control cells (pBABE) were treated with SAHA for 8 h at the doses indicated. After this time, TRAIL (500 ng/ml) was added to some cultures for 15 h. Apoptosis was measured as the percentage of cells with subG1 DNA content and the results show the mean and range of two independent experiments. Western blots show the cFLIP levels after SAHA treatment in pBABE and pBABE-FLIPL cells.

    Invest New Drugs 2012 30, 541-547. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Vorinostat inhibits the tumor growth. NOD ⁄ SCID-B2m-/-mice were injected s.c. with 1×106 MyLa2059 cells into both flanks. When the mice had developed established palpable tumors treatment was initiated (day 1). The mice received either vehicle (black line) or 60 mg ⁄ kg vorinostat (grey line) i.p. five days a week. In total, there were four mice in the group receiving vehicle and three mice in the group receiving vorinostat. The length and width of the tumors were measured continuously until the experiment was terminated on day 20 post treatment initiation. The tumor volume was calculated using the formula V = (a×b2)/2, where a defines the length (mm) and b the width (mm) of the tumor. The histogram shows the average tumor volume per flank ± SEM. * denotes a significant difference (P < 0.05) in the average tumor volume per flank between mice treated with vehicle and vorinostat at the given time-point both by using a one-tailed two samples test with Welch, scorrection and a Mann-Whitney U test.

     

     

    Exp Dermatol 2010 19, 1096-1102. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • (a) Western blot of whole cell extracts demonstrates SAHA and NaB treatment result in increased levels of acetylated histone H3 compared to vehicle controls. (b) Light micrographs of HDACi/vehicle treated cultures illustrate the paucity of neurospheres in HDACi-treated cultures. (c) Quantitative analysis confirms SAHA and NaB inhibit the formation of neurospheres (diameter ≥ 50 μm) and increase the prevalence of small cell clusters (≥ 4 cell, diameter < 50 μm). (d) Flow cytometry using LIVE/DEAD cell stain confirms SAHA and NaB are minimally toxic compared to vehicle controls (n = 3). Scale bar = 100 μm.

    BMC Neurosci 2011 12, 50. Vorinostat (SAHA, MK0683) purchased from Selleck.

    (a) EdU flow cytometry of live cell-gated adult mouse NSCs demonstrates SAHA (**p < 0.01) and NaB (***p < 0.001) significantly inhibit DNA synthesis. (b) Analysis of DNA content by flow cytometry reveals significant accumulation of adult mouse NSCs in G1phase of the cell cycle following SAHA (*p < 0.05) and NaB (*p < 0.05) treatment. (c) Correspondingly the proportion of cells in G2/M phase is significantly reduced following SAHA (*p < 0.05) and NaB (*p < 0.05) treatment. (d) Fluorescence micrographs of HDACi/vehicle treated adult NSCs pulse-labeled with EdU for flow cytometry. Scale bar = 50 μm. Statistical comparisons performed using one-way ANOVA with post hoc Newman-Keuls multiple comparison tests.

    BMC Neurosci 2011 12, 50. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • (a) Immunofluorescence labeling of NeuN, GFAP and Olig2 cell fate markers reveals reduced expression of GFAP (*p < 0.001) and Olig2 (*p < 0.05) in adult mouse NSCs treated with SAHA for 48 hours under proliferation culture conditions and then induced to differentiate for 14 days in culture (two-way ANOVA with Bonferroni post-tests). (b) Western blot of β-catenin protein in nuclear and cytoplasmic fractions of adult mouse NSCs treated with HDACi/vehicle control under proliferation culture conditions. Gapdh and lamin A/C blots are included as loading controls. (c) SAHA and NaB do not significantly alter nuclear/cytoplasmic levels of β-catenin in adult mouse NSCs. Histogram of β-catenin Western blot signal intensities normalized to loading controls (n = 4).

    BMC Neurosci 2011 12, 50. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Morphological changes and histone H3 phosphorylation of HB cells treated with a combination of VX-680 and SAHA. HUH6 and HepT1 were incubated with VX-680 (6 μM) and SAHA (0.5 μM). Nuclei diameter (a) and cell diameter (b) were determined 72 h later by DAPI staining and microscopy. Data represent mean±SD of the diameters from 20 cells in each experiment. (* Two-way ANOVA, Bonferroni test, p \0.05). c Western blot analysis on HUH6 and HepT1 cells were carried out with an anti-phospho-Histone H3 (Ser 10) antibody (p-H3) 24 h after incubation with VX-680 (10 μM), SAHA (0.2 μM) or a combination of both. Controls were left untreated. Western blot analysis showed a decrease in p–H3 after treatment with VX-680 ( lane 2 ) relative to controls ( lane 1 ) and an increase when SAHA was added ( lane 3 ). For the combination of VX-680 and SAHA (lane 4 ) no p-H3 was detected.

    Pediatr Surg Int 2012 28, 579-89. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • Vorinostat promotes C2C12 differentiation.In the image, the red is the myotube indicating differentiation ,the blue is the nuclei.

     

     

    Dr. Akihiko Yoshimura of Akihiko Yoshimura. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Western blot analysis of Acetyl-H3 and H3. 0-20μM SAHA was added.

     

     

    Dr. Zhang of Tianjin Medical University. Vorinostat (SAHA, MK0683) purchased from Selleck.

产品安全说明书

HDAC抑制剂选择性比较

生物活性

产品描述 Vorinostat (suberoylanilide hydroxamic acid, SAHA)是一种HDAC抑制剂，无细胞试验中IC50为~10 nM。
特性 Vorinostat是广谱HDAC活性抑制剂，抑制I和II类酶 。
靶点
HDAC [1]
(Cell-free assay)
~10 nM
体外研究

Vorinostat是小分子量（<300）线性肟酸，抑制HDAC活性，包括乙酰化组蛋白和非组蛋白的积累，抑制培养细胞的增殖，且抑制肿瘤生长。Vorinostat通过结合到酶的活性位点而抑制 HDAC活性。Vorinostat 抑制多种转化细胞增殖（包括 淋巴瘤，多发性骨髓瘤，白血病，和非小细胞肺癌），与对照组相比抑制生长达50% 时的浓度为0.5 到10μM。Vorinostat作用于淋巴瘤和白血病细胞，包括 Burkitt, B-细胞急性淋巴细胞白血病 (B-ALL), MCL, DLBCL, ATL和T-细胞，不同程度抑制细胞增殖。除了抑制转化细胞增殖, Vorinostat 也抑制正常细胞增殖，通过比较Vorinostat 作用于一组细胞系–正常人非纤维细胞(WI-38)和 SV40巨大T抗原转化WI-38(VA-13细胞)而得到证明。Vorinostat 抑制两种类型细胞增殖，这种作用存在剂量依赖性。但发现Vorinostat 对转化细胞具有选择毒性，包括使肿瘤细胞死亡，而对正常细胞只起抑制作用，不会使其死亡。[1] Genistein 和Vorinostat 联用效果比5-aza和Vorinostat 联用作用于诱导细胞死亡有效很多。Genistein和Vorinostat联用作用于ARCaP-E使增殖降低 80 %，作用于ARCaP-M细胞，增殖降低60 %以上。Genistein和Vorinostat 联用抑制细胞增殖具有协同效应。作用于ARCaP-E 细胞(820个基因 诱导和1046个基因抑制) ARCaP-M 细胞，Vorinostat比Genistein 影响更多基因。[2] Vorinostat作用于肿瘤细胞表面，提高Fas蛋白水平，这种作用存在剂量依赖性，且按0.75 μM剂量处理，提高达到一个稳定水平。[3] Vorinostat 抑制肿瘤细胞生长，包括NB4, H460 和HCT-116，IC50分别为0.7μM, 3.4μM和1.2 μM。[4]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
A20 M3m3PGtqdmG|ZTDBd5NigQ>? M2nnbFEhcA>? NGXx[odFVVOR M3L1boFvfGlvSFTBR|Eh[WO2aY\peJkhf2m2aDDJR|UxKG:oIECuNVEzKM7:TR?= NUTiPXdiOTF7NkC0PFk>
Friend leukemic cell MlT1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXu1NEDPxE1? NFv4Nnc4OiCq M2XodmROW09? NFvKdYtKSzVyPUCuPVkh|ryP M3TZWVEzOTB7OUGz
K562 NIPJ[ZJMcW6jc3WgRZN{[Xl? NIXBOHI3KGh? MXvEUXNQ NUS2cHNxUW6qaXLpeIlwdiCxZjDoeY1idiCqaYP0c45mKGSnYXPleJlt[XOnIDjtbZh1fXKnIH;mJGhFSUNzIHHu[EBJTEGFMjmge4l1cCCLQ{WwJI9nKDBwMEGg{txO MYGxNlQyQTN6MB?=
HT1080 NGTjeW9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWrNXpBvPzJiaB?= NGXsU|ZFVVOR MnrYTWM2OD1{LkSg{txO MYCxNlI4ODF5NR?=
H1299 M2W3ZWtqdmG|ZTDBd5NigQ>? MU[yNEBucW5? M1y5O2ROW09? M2HJU2lvcGmkaYTvdpkh[WO2aY\peJkh[WejaX7zeEBJTEGFIHXufplu\SC5aYToJGlEPTBib3[gNE4yQTRizszN M1jWflE1PTJzNEKy
H1299 MmnUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2jkTlczKGh? NE\PV29FVVOR MnXNTWM2OD15LkK0JO69VQ>? MmezNVQ2OjF2MkK=
HeLa M164TWtqdmG|ZTDBd5NigQ>? MoL1N|AhdWmw MkLHTY5pcWKrdH;yfUBkd26lZX70doF1cW:wIHHnZYlve3RiaHnzeI9v\SCmZXHj[ZR6dGG|ZTD3bZRpKEmFNUCgc4YhOC5{ODFOwG0> NH3FO2cyPTZyM{m0PS=>
LOX-IMVI M1:5NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MljLOFghcA>? NYnzOoZCUUN3ME2xMlMh|ryP MYKxOVcyPTR5MB?=
NCI-H226 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYf6OVF5PDhiaB?= NVy1fI5LUUN3ME2yMlYh|ryP MX[xOVcyPTR5MB?=
RXF-631L MoroS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXe0PEBp NW\Me2lFUUN3ME2yJO69VQ>? MkT1NVU4OTV2N{C=
SNB-78 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXm0PEBp NVnt[|I3UUN3ME2xOkDPxE1? NWrYfnd3OTV5MUW0O|A>
St-4 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3;rNFQ5KGh? MYTJR|UxRTVwMjFOwG0> NWf3XlNkOTV5MUW0O|A>
ARP1 MmjLSpVv[3Srb36gRZN{[Xl? M3jWNlIh|ryP Mm\yOkBp MVLJcoR2[3Srb36gc4YhWDJzV1HGNUBo\W6nIHX4dJJme3Orb36= MlnoNVQ4OzR6ME[=
CEM MXPLbY5ie2ViQYPzZZk> MXmxJIg> M13ORWROW09? Mlz4TY5pcWKrdHnvckBw\iCKRFHDJJdqfGhiSVO1NEBw\iByLkOzJO69VQ>? NHToVYsyPjR{MEC2OC=>
HCT15 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MomyOFghcA>? NFjSVplIUTVyPUCuPFIh|ryP M2jVdlE3PzJ|MkK3
NCI-H23 M1fUW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn7yOFghcA>? NFq2Ro5IUTVyPUCuPVIh|ryP NHHnNHQyPjd{M{KyOy=>
GM15850 NX3zcWVGU2mwYYPlJGF{e2G7 NEHMTJQzNjVizszN MVW5OkBp NHjXOZFFVVOR MV;Jcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5iaHnzeI9v\SCKMzDsfZNqdmViMUSgZYNmfHmuYYTpc44hd2ZiRmjOJIdmdmV? M2jpeFE3QTJzM{[3
GM15850 NIjXNZdMcW6jc3WgRZN{[Xl? NF;kNlczNjVizszN MXW5OkBp NUf2flFbTE2VTx?= M2TZe2lvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDobZN1d26nIFi0JIx6e2mwZTC1JIFk\XS7bHH0bY9vKG:oIF\YUkBo\W6n NIjrNJUyPjl{MUO2Oy=>
GM15850 NHPrSGVMcW6jc3WgRZN{[Xl? M4fRXVIvPSEQvF2= NUXoWHZOQTZiaB?= MnTkSG1UVw>? M{G2W2lvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDobZN1d26nIFi0JIx6e2mwZTCxNkBi[2W2eXzheIlwdiCxZjDGXG4h\2WwZR?= M3;wSlE3QTJzM{[3
GM15850 MVzLbY5ie2ViQYPzZZk> MkfYNk42KM7:TR?= M2nYUVk3KGh? NUizVVI1TE2VTx?= M4DXO2lvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDobZN1d26nIFizJIx6e2mwZTC5JIFk\XS7bHH0bY9vKG:oIF\YUkBo\W6n MXWxOlkzOTN4Nx?=
GM15850 MWfLbY5ie2ViQYPzZZk> M2PWbFIvPSEQvF2= NWPpe242QTZiaB?= MXjEUXNQ NIPO[YhKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gbIl{fG:wZTDIOEBtgXOrbnWgPEBi[2W2eXzheIlwdiCxZjDGXG4h\2WwZR?= M{H2OFE3QTJzM{[3
GM15850 MkTKT4lv[XOnIFHzd4F6 MoDXNk42KM7:TR?= MoDNPVYhcA>? NH\ZV2dFVVOR NVzOd|M4UW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJIhqe3SxbnWgTFQhdHm|aX7lJFE3KGGlZYT5cIF1cW:wIH;mJGZZViCpZX7l MnjtNVY6OjF|Nke=
U937 NE\0XHpHfW6ldHnvckBCe3OjeR?= NWrO[mFXPSEQvF2= M1HxdVI1KGh? NYLn[YJDTE2VTx?= MVXD[YxtKGO7Y3zlJIFzemW|dDDifUBi[2O3bYXsZZRqd25iYYSgV{9IOi:PIIDoZZNm NX3VVmFYOTdyMES3NVg>
H661 MmDTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVfRbpZjPDhiaB?= NITMPVFKSzVyPUGg{txO MW[xO|E2PzByOR?=
U937 NULVOZdpTnWwY4Tpc44hSXO|YYm= NU\vWYxLPSEQvF2= M4S1W|I1KGh? NHXSeoVFVVOR Ml7ETY5kemWjc3WgbY4hcGm|dH;u[UBJOyCjY3X0fYxifGmxbh?= MX2xO|Q1Pzd3MB?=
U937 NFzCcIRHfW6ldHnvckBCe3OjeR?= MXOxJO69VQ>? Mn3lNlQhcA>? M{nVTGROW09? M1TWV2Vn\mWldDDvckBidHCqYTD0eYJ2dGmwIHHj[ZR6dGG2aX;u NHu3cWUyPzR2N{e1NC=>
RAW264.7 MVLGeY5kfGmxbjDBd5NigQ>? NXXzNnpLOTBizszN NIHHVFczPGh? NGCwNWp4[XSnch?= M1voNGlvcGmkaYTpc44hd2ZiTGDTMZN1cW23bHH0[YQhXE6IYXzwbIEheHKxZIXjeIlwdiC5aYToJGlEPTBib3[gNE44PiEQvF2= M{Xse|E4PDd5NUG4
RAW264.7 MULGeY5kfGmxbjDBd5NigQ>? MnmzNVAh|ryP NIfxfVkzPGh? MYP3ZZRmeg>? M3TjNWlvcGmkaYTpc44hd2ZiTGDTMZN1cW23bHH0[YQhVk9icILv[JVkfGmxbjD3bZRpKEmFNUCgc4YhOS56ODFOwG0> MYqxO|Q4PzVzOB?=
SC9 NXj4O5JxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEXTd|M1QCCq MnPQTWM2OD1yLk[wOkDPxE1? NX;5XpZ{OTd3MEeyNVk>
ST14A MnzzSpVv[3Srb36gRZN{[Xl? NIDNN3U2KG6P Ml:xO|IhcA>? MnfYTY5kemWjc3WgbY4hWkWVVD;OVnNHKG2UTlGg[ZhxemW|c3nvci=> MVGxO|U3PTl7Mx?=
ST14A MVTGeY5kfGmxbjDBd5NigQ>? NFzZcXc2KG6P NFTIZ444OiCq MXfJcoNz\WG|ZTDpckBGOkZzIH3SUmEh\XiycnXzd4lwdg>? MXyxO|U3PTl7Mx?=
PANC1 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV:5eldjOSEQvF2= M1PvWGlEPTB;MD60OUDPxE1? MmjYNVc2QDh5NES=
PANC1 MmHmSpVv[3Srb36gRZN{[Xl? MorMNUDPxE1? M{\lbVI1KGh? M1XKe2lv[3KnYYPlJIlvKHB{MWfBSlEwS0mSMTDn[Y5mKGW6cILld5Nqd25? MYSxO|U5QDd2NB?=
PANC1 MYPGeY5kfGmxbjDBd5NigQ>? NVjnRoNUOSEQvF2= M{nObVI1KGh? NFvudHZKdmO{ZXHz[UBqdiCyMkfrbZAyKGenbnWg[ZhxemW|c3nvci=> M2DScFE4PTh6N{S0
PT45 NWTnN4VJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFnGV4ZKSzVyPUSg{txO M2W5eFE4PTh6N{S0
ACHN MoG1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MViyNUBp NInUNXVIUTVyPUCuOlUh|ryP M3TSXlE4PjZ{NkC2
PC3 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVuyNUBp MYXHTVUxRTBwN{Gg{txO NXfmNoNnOTd4NkK2NFY>
A431 M{HoT2N6fG:2b4jpZ{BCe3OjeR?= MXS3NkBp NGTtT45KSzVyPUSuNkDPxE1? NXnP[llMOTd4OUG3OlM>
Cal27 NWTpbnVIS3m2b4TvfIlkKEG|c3H5 NHHJV4s4OiCq NHTUNlhKSzVyPUOuNkDPxE1? NETyNW8yPzZ7MUe2Ny=>
CCRF-CEM NW\Qb21SS3m2b4TvfIlkKEG|c3H5 MVW3NkBp MUnJR|UxRTBwODFOwG0> MonrNVc3QTF5NkO=
EOL1 MnLsR5l1d3SxeHnjJGF{e2G7 NYW3fplLPzJiaB?= MlvFTWM2OD1zIN88US=> MY[xO|Y6OTd4Mx?=
Hec-1-A M{DLe2N6fG:2b4jpZ{BCe3OjeR?= MmnzO|IhcA>? MlTxTWM2OD1zIN88US=> NF\IbGUyPzZ7MUe2Ny=>
HeLa MoflT4lv[XOnIFHzd4F6 M{PWe|ExKM7:TR?= M{DXdlMxKG2rbh?= M4\sSWROW09? M2TucmlvcGmkaYTpc44hd2ZicnXjc41jcW6jboSgTGRCSzFid3n0bEBKSzVyIH;mJFAvODJizszN MkixNVc3QTF5NkO=
RKOp21 NXn3c4tIS3m2b4TvfIlkKEG|c3H5 M1nMN|czKGh? Mo\VTWM2OD1zLke2JO69VQ>? M3zGW|E4PjlzN{[z
Saos2 NF3GR4hEgXSxdH;4bYMhSXO|YYm= M2XzNVczKGh? MYnJR|UxRTJwMzFOwG0> NHnGbZYyPzZ7MUe2Ny=>
SK-OV-3 M1;wdmN6fG:2b4jpZ{BCe3OjeR?= M3\FdFczKGh? NWPzcYk6UUN3ME2yMlIh|ryP MUGxO|Y6OTd4Mx?=
U87MG NF;KPGpEgXSxdH;4bYMhSXO|YYm= MXm3NkBp MU\JR|UxRTFzIN88US=> MYmxO|Y6OTd4Mx?=
NUGC3 NFrPcmJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NU\lXmVkPSEQvF2= M3XQ[FI1KGh? NWH6PHJyT0l3ME2yMlc6KM7:TR?= MmXhNVc6ODR6NEO=
CCD1059SK MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4[zTWlEPTB;NEOuOUDPxE1? NWjhW|hoOTh{NEe1OVQ>
HepG2 NIjTOHNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYnJR|UxRTBwMECwOkDPxE1? M4nWTFE5OjR5NUW0
HT1080 NXeydlhbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NInzRlNKSzVyPUCuNFAzPCEQvF2= MXSxPFI1PzV3NB?=
SKBR3 NHPiXlhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXLSUXNJUUN3ME2wMlgh|ryP NGjYXmwyQDJ2N{W1OC=>
SNB78 NUXPNXZ{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUTFR|UxRTF4IN88US=> NYn5PY5{OTh{NEe1OVQ>
SQ20B MlH4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{DBemlEPTB;MzFOwG0> MVSxPFI1PzV3NB?=
St4 NWDudHR2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHfSVVZGSzVyPUWuNkDPxE1? NWrlc4VJOTh{NEe1OVQ>
MCF7 NWLBeYQ6TnWwY4Tpc44hSXO|YYm= M4i0cVExKM7:TR?= MmewPEBp MYXEUXNQ NX6z[YtrUW6mdXP0bY9vKG:oIIT1ZpVtcW5iaInw[ZJi[2W2eXzheIlwdg>? NFjlWXcyQDJ4OUKyOi=>
HEK293 MXHLbY5ie2ViQYPzZZk> MYCxJIg> M2\FPWROW09? MVvJcohq[mm2aX;uJI9nKEiGQVOxJJdqfGhiSVO1NEBw\iByLkCzJO69VQ>? NH:3c2wyQDNyOEW2Ny=>
HEK293 NFjJe5BMcW6jc3WgRZN{[Xl? NGfZOVMyKGh? MmnVSG1UVw>? Mn\VTY5pcWKrdHnvckBw\iCKRFHDN{B4cXSqIFnDOVAhd2ZiMD6wOVch|ryP M1O3N|E5OzB6NU[z
G401 NFjIXoVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF7FUoo4OiCq MV;EUXNQ NUjpSpBvUUN3ME2xJO69VQ>? Mnz3NVg{PzB|N{O=
HeLa NVrGWGY5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUDNfmlmPzJiaB?= NFXhfIFFVVOR MWnJR|UxRTBwNE[g{txO MkTGNVg{PzB|N{O=
Human renal epithelial cell MnfOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYTifYxNPzJiaB?= M1;5SGROW09? MlXpTWM2OD1zNDFOwG0> MWGxPFM4ODN5Mx?=
U937 NX7JVldMTnWwY4Tpc44hSXO|YYm= M1fZcFUh|ryP MorINlQhcA>? MXHJcoR2[3Srb36gc4YhcGm|dH;u[UBJPCCqeYDldoFk\XS7bHH0bY9v MVmxPFM5OTJ|OB?=
U937 M1HXSmZ2dmO2aX;uJGF{e2G7 MVG1JO69VQ>? MX6yOEBp NGL2OYVKdmS3Y4Tpc44hd2ZiYXzwbIEhfHWkdXzpckBpgXCncnHj[ZR6dGG2aX;u Ml\iNVg{QDF{M{i=
U937 M{TOeGZ2dmO2aX;uJGF{e2G7 MU[1JO69VQ>? M{PXPVI1KGh? MUDJcoR2[3Srb36gc4YheDJzIHX4dJJme3Orb36= NGTiNIQyQDN6MUKzPC=>
U937 NXXodpZuTnWwY4Tpc44hSXO|YYm= M{PaU|Uh|ryP M1LEdVI1KGh? MV3JcoR2[3Srb36gc4Yh[XCxcITvd4l{ NYDPeFlmOTh|OEGyN|g>
U937 NHP4c3JHfW6ldHnvckBCe3OjeR?= NIjicWk2KM7:TR?= NI\oNXczPCCq NF\uco9KdmS3Y4Tpc44hd2ZiZ4LhcpVtd2O7dHnjJIRq\m[ncnXueIlifGmxbh?= M{XHeVE5OzhzMkO4
U937 NHjP[FJMcW6jc3WgRZN{[Xl? MXm1JO69VQ>? MXmyOEBp Mlj3TY5pcWKrdHnvckBw\iCqdX3hckBJTEGFMR?= MWexPFM5OTJ|OB?=
U937 NWTlSItGU2mwYYPlJGF{e2G7 MWC1JO69VQ>? NIX6U28zPCCq NXSxTlNHUW6qaXLpeIlwdiCxZjDoeY1idiCKRFHDOC=> NVv3dIlzOTh|OEGyN|g>
HEK-TE MkDoSpVv[3Srb36gRZN{[Xl? MmHPOUDPxE1? M3PJOFZp Mln1SG1UVw>? MXPJcoNz\WG|ZTDpckBpcXO2b37lJGg{KGGlZYT5cIF1cW:w NI\pb3oyQDR|NEG0OC=>
HPDE6c7 NXnqUVFzS3m2b4TvfIlkKEG|c3H5 M1;SOVUxKM7:TR?= MV[3NkBp Mmn5SG1UVw>? NEnMTVBKSzVyPUGuN{DPxE1? MWKxPFQ6PDR4Mx?=
Human microvascular epithelial cell MXrDfZRwfG:6aXOgRZN{[Xl? NX:zdJF[PTBizszN MV[3NkBp M{fVVGROW09? M3:2OGlEPTB;MT6zJO69VQ>? NFnldXEyQDR7NES2Ny=>
Hup T3 NGj2dFBEgXSxdH;4bYMhSXO|YYm= NILWe3E2OCEQvF2= M2HwNFczcA>? MnO1SG1UVw>? NUXrV215UUN3ME2wMlgh|ryP NUn0T5RjOTh2OUS0OlM>
Mia Paca2 NIT2XpZEgXSxdH;4bYMhSXO|YYm= MmmxOVAh|ryP M3qxRlczcA>? MW\EUXNQ NWXnSYo{UUN3ME2xMlEh|ryP NV\JTXd{OTh2OUS0OlM>
Panc 04.03 NGn3fo9EgXSxdH;4bYMhSXO|YYm= NXz1Tm5LPTBizszN MUG3Nog> NGXOOmpFVVOR NULT[llXUUN3ME2xMlIh|ryP MVSxPFQ6PDR4Mx?=
SU 86.86 NFvRRoREgXSxdH;4bYMhSXO|YYm= MoPLOVAh|ryP NVS3TVk3PzKq NGrKdJBFVVOR MnfFTWM2OD1zLkOg{txO Mn\YNVg1QTR2NkO=
HEK293 MoeyT4lv[XOnIFHzd4F6 NGPNPXY{KGh? MlXjTY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDISGFEPiCneIDy[ZN{cW:wIIfpeIghUUN3MDDv[kAxNjBzOTFOwG0> MlfGNVg2PTh4Nkm=
HeLa MXfLbY5ie2ViQYPzZZk> MlfINkBp M4KyXmlvcGmkaYTpc44hd2ZiboXjcIVieiCKRFHDJJdqfGhiSVO1NEBw\iByLkC4N{DPxE1? NVnZOGdTOTh3NUi2Olk>
RAW264.7 MVjGeY5kfGmxbjDBd5NigQ>? MUSyJO69VQ>? MlPDN{42KGh? NXHa[m5VTE2VTx?= NWDtU5FOSW62aX3hcIFzcWGuIHHjeIl3cXS7IHHnZYlve3RiUHzhd41w\Gm3bTDmZYxkcXCjcoXtJIlv\mWldHXkJJdqfGhiSVO1NEBw\iByLkGxJO69VQ>? NVfQZ3FGOTh4NES5Olk>
NB4 M3vnO|Q5cA>? M3vuPGROW09? NXqwPJR[UUN3ME2wMlYh|ryP M2PkcFE5PzJ|M{S5
HEK293 NFHvZY9HfW6ldHnvckBCe3OjeR?= NIrEdnkyOCEQvF2= MonhNlQhcA>? NHGzRpVFVVOR MnH2RYN1cX[jdHnvckBw\iCvb4Xz[UBYdnR|YTDzbYdv[Wyrbneg[ZhxemW|c3Xk MmTkNVkxOjJ4N{W=
HCT116 NH3zeJhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHnke|E4Omh? MkTESG1UVw>? M2\FWWlEPTB;MD6zNUDPxE1? NUnFfZpmOTlyOESyPVQ>
HeLa M1TYS2tqdmG|ZTDBd5NigQ>? MV2yJO69VQ>? MnfBN|AhdWmw MUjEUXNQ NILrTYVKdmirYnn0bY9vKG:oIFjERWMzKGmwIHj1cYFvKEinTHGgZ4VtdHNid3n0bEBKSzVyIH;mJFAvOSEQvF2= M4rIOlE6ODh2Mkm0
IGROV1 NFvMbGlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M13SflczKGh? MWnEUXNQ NFnsXplKSzVyPUKuNkDPxE1? MmHENVkxQDR{OUS=
IGROV1 NYnjNGdzU2mwYYPlJGF{e2G7 Mor5OUDPxE1? NWnrS2hOOjRiaB?= NHm0b4tFVVOR MV\Jcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMheDV|IHHj[ZR6dGG2aX;u NXOzW4VxOTlyOESyPVQ>
IGROV1 MoXxT4lv[XOnIFHzd4F6 Ml7NNVAh|ryP MnOxOEBp M13CfmROW09? NFG2OnVKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaHnzeI9v\S2KNDDhZ4V1gWyjdHnvci=> NF;zUGMyQTB6NEK5OC=>
IGROV1 MVPLbY5ie2ViQYPzZZk> NX\Fd|Z7OTBizszN NI\2ZpY1KGh? M1\De2ROW09? MlHiTY5pcWKrdHnvckBw\iCKRFHDOkBie3Onc4Pl[EBieyCjbIDoZU11fWK3bHnuJIFk\XS7bHH0bY9v M3TIXVE6ODh2Mkm0
T24 MXjLbY5ie2ViQYPzZZk> M4TNWFMhcA>? M3\QU2lv\HWldHnvckBw\iCqaYP0c45mKEh|IHHj[ZR6dGG2aX;uJJdqfGhiRVO1NEBw\iByLkGyJO69VQ>? NGDxUWkyQTB6NEO5OS=>
T24 MVzLbY5ie2ViQYPzZZk> MYGzJIg> MlGzTY5lfWO2aX;uJI9nKGGucHjhJJR2[nWuaX6gZYNmfHmuYYTpc44hf2m2aDDFR|UxKG:oIECuNlUh|ryP NYr5b2NyOTlyOESzPVU>
HeLa MVvLbY5ie2ViQYPzZZk> M2LnVlE2KG2rbh?= NUPKOVdMTE2VTx?= NFnROmVKdmirYnn0bY9vKG:oIFjERWM3KG[{b32gcpVkdGWjcjDlfJRz[WO2IIfpeIghUUN3MDDv[kAxNjB6NUWg{txO NXP2e5IxOTlyOUO4PFQ>
HeLa M17NRWtqdmG|ZTDBd5NigQ>? NGGyc2syPSCvaX6= M1nrUWROW09? NYe2SHdqUW6qaXLpeIlwdiCxZjDISGFEQCCocn;tJI52[2ynYYKg[Zh1emGldDD3bZRpKEmFNUCgc4YhOS56NjFOwG0> M4iySFE6ODl|OEi0
NCI-H69 NGr6VoREgXSxdH;4bYMhSXO|YYm= MVS3NkBp MYDEUXNQ MVfJR|UxRTJwME[g{txO MVKxPVA6Ozh6NB?=
SKMES1 M{HBVGN6fG:2b4jpZ{BCe3OjeR?= NUjWW4FjPzJiaB?= MkP1SG1UVw>? MnfUTWM2OD1{LkSyJO69VQ>? M3fhfFE6ODl|OEi0
S2 MXvLbY5ie2ViQYPzZZk> M2PGeVAvOS1zMDFOwG0> NH:yUngyKGh? Mn[1TY5pcWKrdHnvckBw\iCSbHHzcY9lcXWvIH\hcINqeGG{dX2gTGRCSzFiZYjwdoV{e2WmIIfpeIghUUN3MDDv[kAxNjB3OTFOwG0> M2jiWFE6OzF5NEWw
SHSY5Y M3\RR2tqdmG|ZTDBd5NigQ>? NYLoOpBPOTBizszN MoPtOFghcA>? MXjEUXNQ NEfIb3lKdmirYnn0bY9vKG:oIFjERWMhf2m2aDDJR|UxKG:oIECuOUDPxE1? NVnZVoczOTl|NESxO|U>
SHSY5Y Ml;TR5l1d3SxeHnjJGF{e2G7 MXSxNEDPxE1? MoPxOFghcA>? M4PS[2ROW09? MlfyTWM2OD1{IN88US=> MlvONVk{PDRzN{W=
DMS114 Mlj1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3\KWVQ5KGh? NFPzTnFIUTVyPUKuPUDPxE1? NX;TTY1WOTl2MUmyNFU>
HBC5 M1LJdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NW\Td|QzPDhiaB?= NHXFPWRIUTVyPUG3JO69VQ>? MnSwNVk1OTl{MEW=
SNB78 NV7tXHZKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmTIOFghcA>? MVXHTVUxRTF4IN88US=> NFXW[XUyQTRzOUKwOS=>
HeLa Mom5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mnr1O|IhcA>? MWHEUXNQ Ml;1TWM2OD1yLkS2JO69VQ>? MVSxPVQ1OTh2Nh?=
BHK MYXLbY5ie2ViQYPzZZk> NIjPcIs2KM7:TR?= NYnre2s1OjRiaB?= M17rfWROW09? NH7YN|NKdmirYnn0bY9vKG:oIFjERWM4KGW6cILld5Nm\CCjc4Pld5Nm\CCjczDpcoNz\WG|ZTDpckBxdGG|bXGgcYVu[nKjbnWgSoRmdHSjNUC4JGNHXFJicILveIVqdg>? NGHvXZMyQTl4Nke4PS=>
CFBE41o- NGj1R5JMcW6jc3WgRZN{[Xl? M2\kd|Uh|ryP MU[4JIg> MnTNSG1UVw>? NYK5V496UW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHj5dIVz[WOndInsZZRqd25ib3[gbIl{fG:wZTDINy=> NXLUW5B5OTl7Nk[3PFk>
CFBE41o- MWnLbY5ie2ViQYPzZZk> NVu5NIl2PSEQvF2= NEf1WZg1KGh? NIfJXFJFVVOR MYDJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5ibYX0ZY51KE[mZXz0ZVUxQCCFRmTSJJBzd3SnaX6gcIV3\Wx? NX7JUGg3OTl7Nk[3PFk>
CFBE41o- MlfjT4lv[XOnIFHzd4F6 NH7ZN5oyKM7:TR?= M4HHXFEhcA>? MULEUXNQ NXHZdIh[UW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJGNHXFJicILveIVqdiCuZY\lcC=> NVrLN3F3OTl7Nk[3PFk>
Primary bronchial epithelial cell MWTLbY5ie2ViQYPzZZk> NGjB[2EyKM7:TR?= M2rQNVI1KGh? MXvEUXNQ M4TZNmlvcGmkaYTpc44hd2ZiSFTBR|ch[XO|ZYPz[YQh[XNiaX7keYN1cW:wIH;mJI12fGGwdDDG[IVtfGF3MEigR2ZVWiCycn;0[YlvKGGyaXPhcEB{fXKoYXPlJIxw[2GuaYrheIlwdg>? NFm5fHIyQTl4Nke4PS=>
CFBE41o- NFjUd5JMcW6jc3WgRZN{[Xl? NInkNZEyKM7:TR?= NXHtcoZ6PSCmYYnz M1vOb2ROW09? MlrITY5pcWKrdHnvckBw\iCKRFHDO{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDzeIFjcWyrenH0bY9vKG:oIF\k[Yx1[TVyODDDSnRTKHC{b4TlbY4> NXfzOpk2OTl7Nk[3PFk>
CFBE41o- MorhT4lv[XOnIFHzd4F6 NIK3UYEyKM7:TR?= M4LjOFI1KGh? NHzDclRFVVOR NXjvVI0yUW6qaXLpeIlwdiCxZjDISGFEPyCjc4Pld5Nm\CCjczDpcoNz\WG|ZTDpckBH\GWudHG1NFghS0[WUjDwdo91\WmwIITyZYZncWOtaX7n MXSxPVk3Pjd6OR?=
CFBE41o- MWDLbY5ie2ViQYPzZZk> NX22bmpyPSEQvF2= MWCyOEBp MV7EUXNQ MlTzTY5pcWKrdHnvckBw\iCKRFHDO{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDyZZRmKG:oIH3heJVz[XSrb36gc4YhS0[WUjDwdo91\WmwIITvJIl1eyCpbInjc4Zwem1? NYK0OI5WOTl7Nk[3PFk>
CFBE41o- MUHLbY5ie2ViQYPzZZk> M2DqW|Uh|ryP NWHFfnY4OjRiaB?= M3j4RmROW09? M4fLfWlvcGmkaYTpc44hd2ZiSFTBR|ch[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gd5Ri[mmuaYT5JI9nKE[mZXz0ZVUxQCCFRmTSJJBzd3SnaX6= NWDSVZY4OTl7Nk[3PFk>
CFBE41o- MVXLbY5ie2ViQYPzZZk> MX[1JO69VQ>? NHzTcngzPCCq MYDEUXNQ NUXnS3hsUW6qaXLpeIlwdiCxZjDISGFEPyCjc4Pld5Nm\CCjczDjc5Jz\WO2aX;uJI9nKG23dHHueEBH\GWudHG1NFghS0[WUjD0doFn\mmla3nu[{B1dyClZXzsJJN2em[jY3WgZZMh\2y7Y3;mc5Ju NXzYNVVOOTl7Nk[3PFk>
Primary bronchial epithelial cell NVq4eG5bU2mwYYPlJGF{e2G7 MnXxOUDPxE1? NFnOWoEzPCCq NGPTdmxFVVOR M4HhWGlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnT1Z5Rqd25ib3[gcZV1[W62IF\k[Yx1[TVyODDDSnRTKHC{b4TlbY4h[XCrY3HsJJN2em[jY3WgcI9k[WyrenH0bY9v MV:xPVk3Pjd6OR?=
Primary bronchial epithelial cell NISyZ4pMcW6jc3WgRZN{[Xl? MWWxJO69VQ>? MmLuPVYhcA>? MX3EUXNQ M2TwRmlvcGmkaYTpc44hd2ZiSFTBR|ch[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gd4hwenRiY3nyZ5VqfCCldYLy[Y51ew>? MoDlNVk6PjZ5OEm=
BxPC3 NF3wUVRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXHvdFR3PzJiaB?= NVHpfFFrUUN3ME2yMlch|ryP MXmyNFE1Ozd5OB?=
CAL27 NYPOWldZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX24NZNoPzJiaB?= MoT0TWM2OD1|LkeyJO69VQ>? MoDPNlAyPDN5N{i=
Capan1 MkDES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkHZO|IhcA>? MUnJR|UxRTdwMzFOwG0> NXrmSFc6OjBzNEO3O|g>
HCC827 M1;aSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2n0SlczKGh? NX3QO4l2UUN3ME2xMlgh|ryP NIPkNoYzODF2M{e3PC=>
LNCAP MmL5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mm\DO|IhcA>? NXnUWoszUUN3ME2wMlU5KM7:TR?= M2TWc|IxOTR|N{e4
NCI-H2122 NYLZ[XBnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1LVXlczKGh? M1jR[GlEPTB;Nz61JO69VQ>? MYGyNFE1Ozd5OB?=
NCI-H358 NVnWXWNXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3nGb|czKGh? M{izWWlEPTB;Mj61JO69VQ>? MoK5NlAyPDN5N{i=
SCC15 NXX0OI1VT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1\CU|czKGh? MWnJR|UxRTJwNEmg{txO M1fTNlIxOTR|N{e4
SCC25 Ml;RS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXm0cHNYPzJiaB?= M1uyVmlEPTB;MT65N{DPxE1? NHTkfG8zODF2M{e3PC=>
SKHEP1 MkjCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MojPO|IhcA>? NWW1RWVHUUN3ME2zMlQ3KM7:TR?= NVjKW4sxOjBzNEO3O|g>
BJ M1LMT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFr1SWgyODBizszN NYTrfIJpPDhiaB?= M3WxbWROW09? Mmq0S5Jwf3SqIHnubIljcXSrb36gZZQhOC5yNTD0c{AyODBidV2= NI\WWFkzODF2M{i0NC=>
MUF NYLzRph7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3P4PVExOCEQvF2= NITTPYk1QCCq NGXZO3VFVVOR MVLHdo94fGhiaX7obYJqfGmxbjDheEAxNjB3IITvJFExOCC3TR?= NWHNPW1vOjBzNEO4OFA>
Caco-2 NF\xOI9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MorCNVAxKM7:TR?= NEHJ[mY1QGh? NVrBblk5TE2VTx?= NH3mV4tKSzVyPUiuNUDPxE1? NX61eIJ6OjBzNEO4OFA>
Caco-2 NIrVSJRMcW6jc3WgRZN{[Xl? NH32fpM2KM7:TR?= MVy0JIg> M{nBSmROW09? NHy2eINKdmS3Y4Tpc44hd2ZiSFTBR{1u\WSrYYTl[EBpcXO2b37lJIFk\XS7bHH0bY9vKEmFNUCgc4YhOC5yM{eg{txO MofVNlAyPDN6NEC=
Caco-2 M{DJOGtqdmG|ZTDBd5NigQ>? MVSwMlMyPiCwTTD0c{A{OS54IN88US=> NUHBZXVtPCCq MlzYSG1UVw>? MUHFfEB3cX[xIHnubIljcXSrb36gc4YhcHWvYX6gTGRCSzFid3n0bEBKSzVyIH;mJFAvOTF7IN88US=> NGPFXnUzODF2M{i0NC=>
Caco-2 M2e5fmtqdmG|ZTDBd5NigQ>? M36zNVAvOzF4IH7NJJRwKDNzLk[g{txO MnPGOEBp M1rtemROW09? NVj5eJh3TXhidnn2c{BqdmirYnn0bY9vKG:oIHj1cYFvKEiGQVOzJJdqfGhiSVO1NEBw\iByLkG0O{DPxE1? NXHkfXNXOjBzNEO4OFA>
Caco-2 MonuT4lv[XOnIFHzd4F6 NHH6W4I3NjN{IH7NJJRwKDZ|MjFOwG0> MY[0JIg> NXzDboFLTE2VTx?= MWLFfEB3cX[xIHnubIljcXSrb36gc4YhcHWvYX6gTGRCSzVid3n0bEBKSzVyIH;mJFEzNjZizszN NWPMN3ZyOjBzNEO4OFA>
Caco-2 MW\LbY5ie2ViQYPzZZk> NFPMWFU3NjN{IH7NJJRwKDZ|MjFOwG0> NIHL[4M1KGh? NFPMNHVFVVOR MVvFfEB3cX[xIHnubIljcXSrb36gc4YhcHWvYX6gTGRCSzdid3n0bEBKSzVyIH;mJFQyKM7:TR?= MYqyNFE1Ozh2MB?=
Caco-2 MUPLbY5ie2ViQYPzZZk> MWewMlMyPiCwTTD0c{A{OS54IN88US=> NXrGZY91PCCq NHPmN3dFVVOR NYDDW2lOTXhidnn2c{BqdmirYnn0bY9vKG:oIHj1cYFvKEiGQVO2 M1nUXlIxOTR|OESw
HepG2 M4PjO2tqdmG|ZTDBd5NigQ>? MlvwOUDPxE1? NEPOfmQ3cA>? M1LYZWROW09? MXrJcoR2[3Srb36gc4YhUESDQz3t[YRq[XSnZDDobZN1d26nIHHj[ZR6dGG2aX;u MVqyNFE1Ozh2MB?=
HepG2 MlHlT4lv[XOnIFHzd4F6 MVm1JO69VQ>? NVi2WY5pPmh? Mk\RSG1UVw>? M3vlSmlv\HWldHnvckBw\iCKRFHDMY1m\GmjdHXkJIhqe3SxbnWgbJlx\XKjY3X0fYxifGmxbh?= NGD2[o8zODF2M{i0NC=>
HepG2 NXrkSpBIU2mwYYPlJGF{e2G7 MVu1JO69VQ>? M4P0fVZp NXKxenR{TE2VTx?= MWXJcoR2[3Srb36gc4YhUESDQz3t[YRq[XSnZDDhcJBp[S22dXL1cIlvKGGlZYT5cIF1cW:w NIXPNHgzODF2M{i0NC=>
HepG2 NEHkWmpMcW6jc3WgRZN{[Xl? NFXHWHY2KM7:TR?= NUHX[FlJPmh? NUW2[YtXTE2VTx?= M2TxZWlv\HWldHnvckBw\iCKRFHDMY1m\GmjdHXkJGg{N0h2IHjpd5RwdmViYXPleJlt[XSrb36= M2TGeFIxOTR|OESw
COLO205 NGTKXVNMcW6jc3WgRZN{[Xl? MX2xNEDPxE1? MWiyOEBp MlfwSG1UVw>? NFj2ZlBKdmirYnn0bY9vKG:oIFjERWMyKGG|c3Xzd4VlKGG|IHnu[JVkfGmxbjDv[kBpcXO2b37lJGg{KGGlZYT5cIF1cW:wIIfpeIghUUN3MDDv[kAzNjJizszN NEXIeGUzODR3MUO3PC=>
SCC4 M{m5ZWtqdmG|ZTDBd5NigQ>? M1W0blEh|ryP NFXjfokzPGh? NGHjPGlKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6geJVjfWyrbjDhZ4V1gWyjdHnvci=> M{HFZ|IxPDV{MkK1
SCC4 MULLbY5ie2ViQYPzZZk> NV\XTnVOOSEQvF2= NXG5PXI2OjSq M{DaUWlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDobZN1d26nIHHj[ZR6dGG2aX;u NX7k[5ExOjB2NUKyNlU>
SCC4 MlrWSpVv[3Srb36gRZN{[Xl? NVjZVXZiOSEQvF2= MmfEOUBucW5? NEnvSWxC\2:waYP0JIFkfGm4aYT5JIF1KF[GUjDhd5Nme3OnZDDhd{BqdmS3Y4Tpc44hd2ZiQ2nQNlQh\2WwZTDlfJBz\XO|aX;u MUCyNFQ2OjJ{NR?=
NB4 M4SxNGZ2dmO2aX;uJGF{e2G7 MXi1JO69VQ>? NGr6RlEzPCCq NV;uNVVpTE2VTx?= NXzpWnhiS2WubDDjfYNt\SCjcoLld5Qh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gZYNkfW23bHH0bY9vKGG2IIDy[U1IOSCyaHHz[S=> M1[1e|IxPDlzNESw
NB4 MmPqT4lv[XOnIFHzd4F6 MorROUDPxE1? NYj5cIZ5OjRiaB?= MUnEUXNQ MXjJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5iYXPleJlt[XSnIIT1ZpVtcW5ibHX2[Yw> NIfqfGczODR7MUS0NC=>
NB4 NFLIT4tHfW6ldHnvckBCe3OjeR?= MX21JO69VQ>? M{nRSFI1KGh? NYG1N2lzTE2VTx?= NFOwfJZKdmS3Y4Tpc44hd2ZicEKxW2FHOS:FSWCxJIV5eHKnc4Ppc44> M4\5VlIxPDlzNESw
NB4 Mlj1T4lv[XOnIFHzd4F6 M4nJUlUh|ryP NG\ZOWEzPCCq NVL6RXZHTE2VTx?= M1zjTmlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDobZN1d26nIFizJIFk\XS7bHH0bY9v M3XMXFIxPDlzNESw
NUGC3 M4f1cWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX2xR5NWT0l3ME2yMlk1KM7:TR?= M1zoO|IxQDVyOUex
A549 MW\GeY5kfGmxbjDBd5NigQ>? NWK4bZUyPSEQvF2= NXzhTGpXOyCq NXSwNVdqTE2VTx?= M2f6eGlv\HWldHnvckBw\iCjdYTvdIhi\3liaX6gbJVu[W5iQUW0PUBk\WyuczDhd5Nme3OnZDDhd{BqdmO{ZXHz[UBqdiCOQ{PJTS=> MWGyNFg2PTJyOB?=
HUT78 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M17afFczKGh? NWjpT|VGTE2VTx?= M4TxTGdKPTB;MD6zJO69VQ>? NV;jN2xjOjB6OESyNFg>
U937 NUO5ZWZGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFjMbVI4OiCq MYLEUXNQ NYLmUY9sT0l3ME2wMlM6KM7:TR?= NUX2bnhWOjB6OESyNFg>
A431 NE[zV3hEgXSxdH;4bYMhSXO|YYm= NESzTZc4OiCq NX3tSJV2S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTR|MTDj[YxteyCxdnXy[ZhxemW|c3nu[{BGT0[UIIfpeIghUUN3MDDv[kA1NjJizszN M{fDTFIyODhyNkK5
A549 NXKxXno4S3m2b4TvfIlkKEG|c3H5 MVW3NkBp MWPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJI93\XKneIDy[ZN{cW6pIFjERWMhf2m2aDDJR|UxKG:oIEGuPEDPxE1? MkPiNlExQDB4Mkm=
CAL27 NYnlWlZWS3m2b4TvfIlkKEG|c3H5 NVPtfZpRPzJiaB?= NEDuO|dEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBESUx{NzDj[YxteyCxdnXy[ZhxemW|c3nu[{BGT0[UIIfpeIghUUN3MDDv[kA{NjJizszN NEW0[mYzOTB6ME[yPS=>
HeLa NEPVUnBEgXSxdH;4bYMhSXO|YYm= Mm\QO|IhcA>? NWi2Zpo1S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCxdnXy[ZhxemW|c3nu[{BJTEGFIIfpeIghUUN3MDDv[kAyNjVizszN NUS1NZVsOjFyOEC2Nlk>
Sf21 NX64flJqU2mwYYPlJGF{e2G7 NIHrXmY{KGh? MWLJcohq[mm2aX;uJI9nKE[uYXegeIFo\2WmIHj1cYFvKHKnY3;tZolv[W62IFjERWM5KGW6cILld5Nm\CC5aYToJGlEPTBib3[gNU4zKM7:TR?= MoT6NlExQDB4Mkm=
SKBR3 NXLKfZh2S3m2b4TvfIlkKEG|c3H5 NWCydHU4PzJiaB?= NWTySGsxS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0uEUkOgZ4VtdHNib4\ldoV5eHKnc4PpcochUEWUMjD3bZRpKEmFNUCgc4YhOi54IN88US=> MYqyNVA5ODZ{OR?=
SKOV3 Mlr1R5l1d3SxeHnjJGF{e2G7 MmjGO|IhcA>? MUTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTT29XOyClZXzsd{BwfmW{ZYjwdoV{e2mwZzDISXIzKHerdHigTWM2OCCxZjCyMlIh|ryP MnrqNlExQDB4Mkm=
COR-L23 NYT6OGU3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHOyc5AyOCEQvF2= NYPiZ4RjPzJiaB?= NV;KSnluTE2VTx?= M4HNN2dKPTB;MT6xJO69VQ>? M3rkR|IyODhyNkS3
DU145 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGLlbHgyOCEQvF2= M2jwfFczKGh? M4nzeGROW09? MWnHTVUxRTFwMEWg{txO NYX2c4ZEOjFyOEC2OFc>
LoVo NVfJSVhXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkjENVAh|ryP NF7JU5c4OiCq NUHjOHRRTE2VTx?= MWjHTVUxRTFwNzFOwG0> MYiyNVA5ODZ2Nx?=
MCR5-SV2 NIXndoFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlS3NVAh|ryP NWX0UZllPzJiaB?= NYHDcZQ{TE2VTx?= MkC4S2k2OD1{LkGg{txO NYG3SGRNOjFyOEC2OFc>
HCT116 NFPm[5pMcW6jc3WgRZN{[Xl? NEK1Nmk{OCEQvF2= M3jmSVMxKGh? M1y1b2ROW09? NIfKOmNKdmirYnn0bY9vKG:oIFjERWM3KGG|c3Xzd4VlKGG|IHnu[JVkfGmxbjDv[kBidHCqYT30eYJ2dGmwIHHj[ZR6dGG2aX;u NWq5fFVGOjFyOEC2OFc>
HCT116 M{ezUWtqdmG|ZTDBd5NigQ>? M{DzR|MxKM7:TR?= M3HNbFMxKGh? NXPoUYZITE2VTx?= NYLIdWxZUW6qaXLpeIlwdiCxZjDISGFEOSCjc4Pld5Nm\CCjczDpcoR2[3Srb36gc4YhcGm|dH;u[UBJO0t7IHHj[ZR6dGG2aX;u NG\DTJczOTB6ME[0Oy=>
U937 MmSzT4lv[XOnIFHzd4F6 MVG1JO69VQ>? MV[yOEBp MlzUSG1UVw>? M2TGNGlvcGmkaYTpc44hd2ZiaHnzeI9v\SCjY3X0fYx1emGwc3\ldoF{\SCjc4Pld5Nm\CCjczDpcoNz\WG|ZTDv[kBi[2W2eXzheIlwdiCxZjDobZN1d26nIFizJIF1KEt7 MlzPNlEzQTJ2OUK=
U937 M1PUbmtqdmG|ZTDBd5NigQ>? M2[0WVUh|ryP NFjPdmMzPCCq MnzpSG1UVw>? M3;iOWlvcGmkaYTpc44hd2ZiaHnzeI9v\SCjY3X0fYx1emGwc3\ldoF{\SCjc4Pld5Nm\CCjczDpcoNz\WG|ZTDv[kBi[2W2eXzheIlwdiCxZjDobZN1d26nIFizJIF1KEtzOB?= Ml2xNlEzQTJ2OUK=
U937 NXix[lRtU2mwYYPlJGF{e2G7 Mn\4OUDPxE1? MoOyNlQhcA>? M1mzUWROW09? MkHpTY5pcWKrdHnvckBw\iCqaYP0c45mKGGlZYT5cJRz[W6|ZnXyZZNmKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIH;mJJBidi2jY3X0fYxifGWmIHjpd5RwdmViSESgcIV3\Wx? M3T0dFIyOjl{NEmy
U937 NUjzNVdPU2mwYYPlJGF{e2G7 MoHOOUDPxE1? NIXU[40yPSCvaX6= NYrXR4hzTE2VTx?= M2W1ZmlvcGmkaYTpc44hd2ZiaHnzeI9v\SCjY3X0fYx1emGwc3\ldoF{\SCjc4Pld5Nm\CCjczDpcoNz\WG|ZTDv[kBpcXO2b37lJGg{KGGlZYT5cIF1cW:wIHzleoVt NVS5coV1OjF{OUK0PVI>
A2780 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1\KSFk3KGh? MnnxSG1UVw>? NUnyVlZnUUN3ME2xMlYzKM7:TR?= NYrU[3JoOjF4M{S0N|A>
COLO205 MkXsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXy5OkBp M4PCXmROW09? MXXJR|UxRTJwMUKg{txO NW\scIJJOjF4M{S0N|A>
Hep3B MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUK0PEBp NE\HcopFVVOR NVfNOZFnT0l3ME2xMlIyKM7:TR?= MoDyNlE4OTJzNE[=
GM11272 NVjOUFdTTnWwY4Tpc44hSXO|YYm= MnvoNVAxKG6P MlO4O|IhcA>? NUjufFVnTE2VTx?= NU[4cXljWmWjY4TpeoF1cW:wIH;mJG1mS3B{IH31eIFvfCCneIDy[ZN{cW:wIHH0JFExKHSxIEGwNEBvVQ>? MXSyNVg1ODdzNh?=
CFBE41o M2LINGtqdmG|ZTDBd5NigQ>? M4G5dVUh|ryP M4naN2ROW09? MX7Ec5dvKHKnZ4XsZZRqd25ib3[gTGRCSzdiYYSgNE4zKHSxIEWgeW0> NF\ibHUzOTl6NEm1PC=>
CFBE41o MWrGeY5kfGmxbjDBd5NigQ>? NWnIO4ttOSEQvF2= MUCyOEBp NWHEcYJpTE2VTx?= MXHS[ZN1d3KjdHnvckBw\iCFRmTSJIRmdHSjRkWwPEBufXSjboSgeJJi\m[rY3vpcochfG9iY3XscEB{fXKoYXPlJIF{KGeueXPv[o9zdXN? NVHKPHZpOjF7OES5OVg>
DU145 M1TXfmtqdmG|ZTDBd5NigQ>? M33DVlIvPSEQvF2= NFjGVZozPCCq NVjtc3JSTE2VTx?= NIXlRlhKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNidYDy[Yd2dGG2aX;uJI9nKHB{MYfh[lEheHKxdHXpckBmgHC{ZYPzbY9v M4\PTFIzOjZyMU[2
DU145 NFT2Z5ZMcW6jc3WgRZN{[Xl? MXi1JO69VQ>? MkX6NlQhcA>? Ml3ISG1UVw>? NUftZWxSUW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHjpd5RwdmViSESgZYNmfHmuYYTpc44> NVjUU3U5OjJ{NkCxOlY>
DU145 MmXJT4lv[XOnIFHzd4F6 NF;3ToI2KM7:TR?= NUC1V2d[OjRiaB?= MV\EUXNQ NWjtPXBDUW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHjpd5RwdmViSEOgbJlx\XKjY3X0fYxifGmxbh?= NYf0S49jOjJ{NkCxOlY>
786-0 NVrZbXVOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWK2MlIh|ryP NUDETVdzPzJiaB?= MWnEUXNQ M2PGVmdKPTB;Mz6yJO69VQ>? NYHTXYtKOjJ2M{W2Olk>
A498 NX7w[YRnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXLJOYVJPi5{IN88US=> NY\ZSYtTPzJiaB?= M1P6V2ROW09? MnTRS2k2OD1zLk[g{txO MXmyNlQ{PTZ4OR?=
A549/ATCC M13wZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHWzPIY3NjJizszN MlTwO|IhcA>? NH;ZbY1FVVOR Mor2S2k2OD1zLk[g{txO MlfVNlI1OzV4Nkm=
ACHN NWGyOIVvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVrpZoxsPi5{IN88US=> NVXUSGZMPzJiaB?= MkfOSG1UVw>? NHvHd4ZIUTVyPUGuN{DPxE1? NEDwPXczOjR|NU[2PS=>
BT549 NWjw[VFoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4\UbFYvOiEQvF2= NIX3fZo4OiCq NEC5ZXJFVVOR NIDqeZhIUTVyPUGuN{DPxE1? NE\FUY4zOjR|NU[2PS=>
EKVX M33sd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV;NO2pEPi5{IN88US=> NVTHcYo2PzJiaB?= MW\EUXNQ NXvBNVc5T0l3ME2xMlMh|ryP M3:4NVIzPDN3Nk[5
HCT15 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVfQcGtsPi5{IN88US=> MXO3NkBp M3izS2ROW09? NYnhWWQ6T0l3ME2yMlUh|ryP NU\1UGN[OjJ2M{W2Olk>
HOP92 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXm2MlIh|ryP MX:3NkBp M1rIOmROW09? MXPHTVUxRTRizszN Mk\NNlI1OzV4Nkm=
IGROV1 NEC4T|hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWn0V|BiPi5{IN88US=> MoPJO|IhcA>? M2HESmROW09? NFfuPWdIUTVyPUGuN{DPxE1? NEPEeYYzOjR|NU[2PS=>
LOXIMVI MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUe2MlIh|ryP M{\NS|czKGh? NH\tUGpFVVOR MmXYS2k2OD1zIN88US=> NIf0dYkzOjR|NU[2PS=>
M14 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYq2MlIh|ryP MYi3NkBp M{Xh[GROW09? MWDHTVUxRTFwMzFOwG0> MkfiNlI1OzV4Nkm=
MALME-3M NWfsNWQ4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWLiNmc6Pi5{IN88US=> NYr0RZd1PzJiaB?= NFWzeIlFVVOR NHvTNYxIUTVyPUCuN|Ih|ryP NH\1TVczOjR|NU[2PS=>
MCF10A NVTKSpFxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1PPflYvOiEQvF2= MVy0PEBp M2HSdGROW09? MU\HTVUxRTlwNjFOwG0> M2TNelIzPDN3Nk[5
MDA-MB-435 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkDpOk4zKM7:TR?= M{m0fVczKGh? M4SzcmROW09? NVnXR4d2T0l3ME2wMlUh|ryP MkHrNlI1OzV4Nkm=
MDA-MB-468 NUjEeVFYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYm2MlIh|ryP NWTn[WJkPzJiaB?= NH3DV|RFVVOR NG\n[nlIUTVyPUCuOlMh|ryP NGnJfFQzOjR|NU[2PS=>
MOLT4 Mof2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2HHelYvOiEQvF2= M3ixdVczKGh? M4[zZmROW09? NI\VW|RIUTVyPUCuOEDPxE1? MnfUNlI1OzV4Nkm=
NCI-ADR-RES M2DaZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUfGWHlUPi5{IN88US=> MUK3NkBp MWPEUXNQ MlXmS2k2OD1yLkG2JO69VQ>? M4j1XlIzPDN3Nk[5
NCI-H23 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1HicFYvOiEQvF2= M4T5TlczKGh? MXfEUXNQ NYC2OpRxT0l3ME2xJO69VQ>? NF7sflAzOjR|NU[2PS=>
NCI-H322M NFm4cGNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MljoOk4zKM7:TR?= NGHVeHU4OiCq MlzySG1UVw>? M{e3TmdKPTB;MD63PUDPxE1? NVTIU25COjJ2M{W2Olk>
NCI-H460 NIPpWJVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NG\PNIk3NjJizszN Ml\PO|IhcA>? NFLxb3FFVVOR M1qwb2dKPTB;MD63PUDPxE1? M{jsV|IzPDN3Nk[5
NCI-H522 NIiyUGtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2WycFYvOiEQvF2= MomwO|IhcA>? MV7EUXNQ NI\5ZXBIUTVyPUCuOUDPxE1? NFXOUnMzOjR|NU[2PS=>
OVCAR3 NFzWZYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWf3U5BLPi5{IN88US=> MorwO|IhcA>? M4HndGROW09? M4L5PWdKPTB;MT6zJO69VQ>? Mlm0NlI1OzV4Nkm=
OVCAR4 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnjqOk4zKM7:TR?= NUD3codVPzJiaB?= MYXEUXNQ NFj0RY5IUTVyPUSg{txO M1LYZlIzPDN3Nk[5
OVCAR5 NVrtPWl6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXm2MlIh|ryP MXq3NkBp NITDeY9FVVOR NHG2PIlIUTVyPUCuO|kh|ryP NEfmUnIzOjR|NU[2PS=>
OVCAR8 NYTTV|BTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYnmNXdJPi5{IN88US=> NHjISJY4OiCq NHmzc|RFVVOR NYnq[WY6T0l3ME2wMlUh|ryP NV\UU20xOjJ2M{W2Olk>
RXF393 NGPVZ41Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIr2NXI3NjJizszN MkS3O|IhcA>? MXvEUXNQ NHuz[mNIUTVyPUGuN{DPxE1? MlfHNlI1OzV4Nkm=
SF268 NVPrXWlVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH7ENFQ3NjJizszN M1vReVczKGh? MWrEUXNQ M2\3dWdKPTB;MT62JO69VQ>? NFyxVZIzOjR|NU[2PS=>
SF295 NX7ub3M{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mnn5Ok4zKM7:TR?= Moj1O|IhcA>? M4fmWGROW09? M{\XbmdKPTB;MT62JO69VQ>? NWDBVopjOjJ2M{W2Olk>
SF539 M2LLUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmrpOk4zKM7:TR?= NUWzSGVjPzJiaB?= M3TPc2ROW09? M4fjWmdKPTB;MjFOwG0> MnjuNlI1OzV4Nkm=
SK-MEL-2 NWnpfVN7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYS2MlIh|ryP NHr3XnE4OiCq NHXTOnFFVVOR MoDBS2k2OD1zLkOg{txO M3HhPVIzPDN3Nk[5
SK-MEL-28 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHvjbog3NjJizszN NH3ZR3Y4OiCq MW\EUXNQ MkXHS2k2OD1zIN88US=> Mn3TNlI1OzV4Nkm=
SK-MEL-5 NH36WJhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWS2MlIh|ryP NHn3VZo4OiCq NWTae2pkTE2VTx?= NYP3SY5kT0l3ME2wMlY{KM7:TR?= M2[3blIzPDN3Nk[5
SKOV3 M3z4Tmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUHJPVVNPi5{IN88US=> MWS3NkBp NXvCSVh[TE2VTx?= NHfIZ|lIUTVyPUGg{txO M3XzOlIzPDN3Nk[5
SN12C M1XoVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWe2c5VxPi5{IN88US=> NUHmNGVzPzJiaB?= NHW1NnhFVVOR NXKzXHRKT0l3ME2yJO69VQ>? MWqyNlQ{PTZ4OR?=
SNB19 NX;BWZRyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUK2MlIh|ryP MW[3NkBp NFTMdHpFVVOR MlvvS2k2OD1yLk[zJO69VQ>? MYiyNlQ{PTZ4OR?=
SNB75 NUjEOYk5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3rsZVYvOiEQvF2= M162dFczKGh? MlHvSG1UVw>? MWfHTVUxRTBwN{mg{txO NGrTOFczOjR|NU[2PS=>
SR MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MU[2MlIh|ryP NFnBcnE4OiCq NV7IT4xQTE2VTx?= NVfCPVFUT0l3ME2wMlQh|ryP NF3hS3YzOjR|NU[2PS=>
T47D NF;kSpZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH3PXZI3NjJizszN MXe3NkBp MkjUSG1UVw>? M4f5e2dKPTB;MD61JO69VQ>? Mlq3NlI1OzV4Nkm=
TK10 MmrKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml3oOk4zKM7:TR?= NHTYU3I4OiCq M1:4ZWROW09? NIDobZZIUTVyPUCuOlMh|ryP NXL4XlYxOjJ2M{W2Olk>
UACC257 NXH1UHQ1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1qxNlYvOiEQvF2= MVW3NkBp NHjybJVFVVOR MVLHTVUxRTBwNTFOwG0> NXTSeotoOjJ2M{W2Olk>
UACC62 NI\jRo9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml[zOk4zKM7:TR?= NF;Me404OiCq Mlr0SG1UVw>? M4GxRmdKPTB;MD60JO69VQ>? MojZNlI1OzV4Nkm=
UO31 MkDPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUG2MlIh|ryP M3TOUlczKGh? M3n2[WROW09? NXzHZVJOT0l3ME2wMlUh|ryP MUeyNlQ{PTZ4OR?=
Hep3B NH32WI9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3HaU|Q5KGh? M{[1SmROW09? NEPYXlZIUTVyPUCuOlkh|ryP M{jDcFIzPDN7OE[z
BE(2)-C M1OxcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUK3NkBp MlHoSG1UVw>? MoPzTWM4OD1{IN88US=> NVPYem9COjJ7M{KzNVY>
Bel7402 NGj1SY1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4\qN|czKGh? Mn3GSG1UVw>? Mn[1S2k6OD1zNzFOwG0> NIPmTpkzOzB4MUO3Oi=>
Bel7404 M1LERWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV\KN5FFPzJiaB?= M1rSWmROW09? M3:0NGdKQTB;MUig{txO M3ThcVI{ODZzM{e2
BGC823 NWTQVFRzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1rPc|czKGh? MXfEUXNQ NGPEXVlIUTlyPUeuOUDPxE1? MXWyN|A3OTN5Nh?=
MGC803 NEfWSm5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmPKO|IhcA>? M1PGUWROW09? NFLtPXJIUTlyPUGwMlgh|ryP MYWyN|A3OTN5Nh?=
SGC7901 MmTES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVm3NkBp M3fnWGROW09? NXzDOVdFT0l7ME25MlQh|ryP NGXXdI4zOzB4MUO3Oi=>
SKHEP1 Mn\5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmXaO|IhcA>? M4XNSGROW09? MYDHTVkxRTF5IN88US=> M1zw[VI{ODZzM{e2
SMMC7721 NWfPfXhiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnPVO|IhcA>? MlXzSG1UVw>? MWnHTVkxRTJyIN88US=> MVSyN|A3OTN5Nh?=
NUGC3 M4rOW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn70NVAh|ryP NX30UGZpT0l;Mj65OEDPxE1? MoG3NlMyPjN|M{K=
A2780 CisR MXLLbY5ie2ViQYPzZZk> NWC2UItYOThiaB?= MXzJcohq[mm2aX;uJI9nKEiGQVOge4l1cCCLQ{WwJI9nKDBwNESg{txO MVKyN|I2OjZyMx?=
CAL27 sens NEi1Z4ZMcW6jc3WgRZN{[Xl? Moj0NVghcA>? M{e4VmlvcGmkaYTpc44hd2ZiSFTBR{B4cXSqIFnDOVAhd2ZiMD6zOkDPxE1? MnfBNlMzPTJ4MEO=
CAL27 CisR M3vPO2tqdmG|ZTDBd5NigQ>? MoDUNVghcA>? NEPnUHFKdmirYnn0bY9vKG:oIFjERWMhf2m2aDDJR|UxKG:oIECuOlEh|ryP MnvpNlMzPTJ4MEO=
KYSE-510 CisR MWTLbY5ie2ViQYPzZZk> MVmxPEBp MX3Jcohq[mm2aX;uJI9nKEiGQVOge4l1cCCLQ{WwJI9nKDBwNUmg{txO NXvScoN3OjN{NUK2NFM>
KYSE-510 sens NV;2RmZCU2mwYYPlJGF{e2G7 M134ZVE5KGh? M1nT[2lvcGmkaYTpc44hd2ZiSFTBR{B4cXSqIFnDOVAhd2ZiMD63JO69VQ>? NHT4XFMzOzJ3Mk[wNy=>
MDA-MB-231 sens MXzLbY5ie2ViQYPzZZk> NUHWdXRWOThiaB?= M37ROmlvcGmkaYTpc44hd2ZiSFTBR{B4cXSqIFnDOVAhd2ZiMD62NUDPxE1? NFrTT4IzOzJ3Mk[wNy=>
MDA-MB-231 CisR NFzi[nlMcW6jc3WgRZN{[Xl? MVWxPEBp M17QcGlvcGmkaYTpc44hd2ZiSFTBR{B4cXSqIFnDOVAhd2ZiMD62NUDPxE1? NWq2fGtDOjN{NUK2NFM>
ES2 M4fadGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYi0PEBp NFHoO2hFVVOR MnP4TWM2OD1zMj63JO69VQ>? NI\uR28zOzR7M{S0PS=>
MDA-MB-231 MVXLbY5ie2ViQYPzZZk> NGLRelQyOCEQvF2= MnLFN|AhdWmw MXHEUXNQ M2X0NmlvcGmkaYTpc44hd2ZiSFTBR|Ji NGDLR20zOzR7M{S0PS=>
MDA-MB-231 NIDXS3lMcW6jc3WgRZN{[Xl? NFjSSFQyKM7:TR?= NHrMfYYzPCCq MnPsSG1UVw>? MVHJcohq[mm2aX;uJI9nKEiGQVO2JIF{e2W|c3XkJIF{KGGlZYT5cIF1cW:wIHzleoVteyCxZjD0eYJ2dGmw M4HidFI{PDl|NES5
HS68 MYLDfZRwfG:6aXOgRZN{[Xl? MXWxNEDPxE1? MUC3NkBp M37Cb2ROW09? M3PMN2lEPTB;ND62JO69VQ>? NXXMTnVjOjN3N{C1OFI>
MEF MnfXR5l1d3SxeHnjJGF{e2G7 M{C1fFExKM7:TR?= MmLuO|IhcA>? MnXkSG1UVw>? MVrJR|UxRTRwNDFOwG0> MXGyN|U4ODV2Mh?=
BGC823 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV\MUoQ5TE2VTx?= NE\VNXVIUTVyPUOuNFkh|ryP M3PMfVI{PjBzN{C2
High5 NX3aPZFCU2mwYYPlJGF{e2G7 NIjI[IszPCCq MV7Jcohq[mm2aX;uJI9nKGi3bXHuJJJm[2:vYnnuZY51KEiGQVO2JJdqfGhiSVO1NEBw\iByLkC5JO69VQ>? MmTaNlM3ODJ3MkO=
High5 Ml\JT4lv[XOnIFHzd4F6 NHjwUpQzPCCq MVLJcohq[mm2aX;uJI9nKGi3bXHuJJJm[2:vYnnuZY51KEiGQVOxJJdqfGhiSVO1NEBw\iByLkGyJO69VQ>? MmTMNlM3ODJ3MkO=
High5 M{PVTWtqdmG|ZTDBd5NigQ>? MoThNlQhcA>? M{PGUmlvcGmkaYTpc44hd2ZiaIXtZY4hemWlb33ibY5idnRiSFTBR|Mhf2m2aDDJR|UxKG:oIECuNVch|ryP NEnK[FkzOzZyMkWyNy=>
A549 NFHCNWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFX5XIZFVVOR MVvJR|UxRTFwMEe5JO69VQ>? NHL5eHMzOzZ2NEKxNC=>
HCT116 NYj5VXlmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2HpO2ROW09? MWrJR|UxRTBwN{W3JO69VQ>? NUXDZ2ZROjN4NESyNVA>
K562 MnXPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVXwclg6TE2VTx?= NH3sT4xKSzVyPUCuOlQ2KM7:TR?= MkLqNlM3PDR{MUC=
GBC-SD Mo\PS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml:wOUDPxE1? NEfaSW44OiCq NFL4bIRFVVOR NHTSU|hKSzVyPUG0Mlgh|ryP NFPhV|gzOzdyN{K2NC=>
HGC27 NVLFfpY{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIXmPFM2KM7:TR?= MWG3NkBp MUHEUXNQ MnzNTWM2OD13LkSg{txO NUDIWVF3OjN5MEeyOlA>
HL60 M4fHRWtqdmG|ZTDBd5NigQ>? MWm1JO69VQ>? MXeyOEBp NXzkOphMTE2VTx?= MoHZTY5pcWKrdHnvckBw\iCKRFHD MmnGNlM4ODd{NkC=
Vero MmnNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWO4NFd3PzJiaB?= Mo\ESG1UVw>? NYO2TVFsUUN3ME2wMlkh|ryP NHzjUHYzOzd6NkS1Ni=>
NCI60 MWnDfZRwfG:6aXOgRZN{[Xl? NYjibo5IPDhiaB?= MnfqSG1UVw>? NUSy[VczT0l;MD61N{DPxE1? MmnWNlQxOTV|Mke=
SW620 MkL1R5l1d3SxeHnjJGF{e2G7 MV20PEBp M4LUd2ROW09? MXnHTV0xNjV2IN88US=> Mle2NlQxOTV|Mke=
U251 Mli3R5l1d3SxeHnjJGF{e2G7 MkDSOFghcA>? NGjLbXhFVVOR NWDXRo1qT0l;MT61N{DPxE1? MWWyOFAyPTN{Nx?=
KM12 NInIXmJEgXSxdH;4bYMhSXO|YYm= MVe0PEBp M1rITmROW09? MkXUS2k:OS56ODFOwG0> MnG2NlQxOTV|Mke=
Hs578T MYjDfZRwfG:6aXOgRZN{[Xl? M17DWFQ5KGh? NVizeXVDTE2VTx?= M13uemdKRTRwOEOg{txO MW[yOFAyPTN{Nx?=
MDA-MB-231 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF7qd|I1QCCq MlLSTWM2OD1yLkG2JO69VQ>? M2\5dlI1ODl3MEG2
MCF7 NX;BU2h2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkLXOFghcA>? M3;1TWdKRTBwNEWg{txO MnPnNlQyOTl3NUW=
MDA-MB-435 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXfiWlAzPDhiaB?= NID6eWVIUT1yLki4JO69VQ>? MkHnNlQyOTl3NUW=
AsPC1 NUDnTVVzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmjQN|Ah|ryP M1rjSFQ5KGh? NFnTbW5FVVOR MU\JR|UxRTNwNk[g{txO NXnnRVdOOjRzOEWzO|g>
Jurkat E6.1 MV;LbY5ie2ViQYPzZZk> MoG1NkBp NF;lXWdFVVOR MXHJcohq[mm2aX;uJI9nKEiGQVO0JJdqfGhiSVO1NEBw\iByLkC0JO69VQ>? NFX5Nm4zPDJ4MUi2Ni=>
KG1 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkjuOFghcA>? NH;FZohKSzVyPUGuNVUh|ryP MknQNlQ2OjVyMEO=
HEL NVm4ZnhpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWC0PEBp MV7EUXNQ M2jpUWlEPTB;MD60PUDPxE1? M3:2V|I1Pjl2MEW1
HSC3 MonjR5l1d3SxeHnjJGF{e2G7 NX3qdWg4OTJiaB?= MWjEUXNQ MlvsTWM2OD1yLkexJO69VQ>? M{LwcFI1PzZ4NU[w
HT-29 MnftR5l1d3SxeHnjJGF{e2G7 M{\lTFEzKGh? NEjQcppFVVOR MYDJR|UxRTBwN{Kg{txO MnLmNlQ4PjZ3NkC=
KB MlPFR5l1d3SxeHnjJGF{e2G7 MVuxNkBp MoHQSG1UVw>? NVOzUmpSUUN3ME2wMlc2KM7:TR?= M3XjO|I1PzZ4NU[w
H460 M4rWZWN6fG:2b4jpZ{BCe3OjeR?= NGrZdJoyOiCq MXjEUXNQ M{\UbWlEPTB;MD64NkDPxE1? Mk\tNlQ4PjZ3NkC=
MONE1 M1z5VGN6fG:2b4jpZ{BCe3OjeR?= NH73[XUyOiCq M1TwSWROW09? MWPJR|UxRTFwMUig{txO NW\VbVBPOjR5Nk[1OlA>
MKN45 NV7WUHozS3m2b4TvfIlkKEG|c3H5 M17HdlEzKGh? MVHEUXNQ NXLJ[pE6UUN3ME2xMlI2KM7:TR?= MknFNlQ4PjZ3NkC=
TSGH MkT4R5l1d3SxeHnjJGF{e2G7 MoDKNVIhcA>? NWO0OG1kTE2VTx?= MXrJR|UxRTJwMEmg{txO NIrjelczPDd4NkW2NC=>
HL60 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWW3NkBp NXuyO5RqTE2VTx?= M3PQc2dKPTB;MD65N{DPxE1? MYWyOFkxODVyMB?=
HEK293 M13Cc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH24TWo4OiCq MlnESG1UVw>? NHfTeXpIUTVyPUGzJO69VQ>? M4DBWVI1QTByNUCw
Jurkat MXHDfZRwfG:6aXOgRZN{[Xl? MWixNFAh|ryP NHP2epE4OiCq NFuzRmhIUTVyPUCuPUDPxE1? MXqyOFkxODd2Mx?=
GM15850 NYPONHRMU2mwYYPlJGF{e2G7 NX\RZYhWOi53IN88US=> M1:yR|k3KGh? NILRTJRFVVOR M1PWPYRw\XNibn;0JIlvcGmkaYSgTGRCSyCjc4Pld5Nm\CCjczDpcoNz\WG|ZTDpckBpcXO2b37lJGg{KGy7c3nu[UAyPCCjY3X0fYxifGmxbjDv[kBHYE5iZ3Xu[S=> NYjEWYZlOTZ7MkGzOlc>
GM15850 M1j4R2tqdmG|ZTDBd5NigQ>? NHHqSVYzNjVizszN M4Sxd|k3KGh? MYnEUXNQ MUjkc4V{KG6xdDDpcohq[mm2IFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gbIl{fG:wZTDIOEBtgXOrbnWgOUBi[2W2eXzheIlwdiCxZjDGXG4h\2WwZR?= MnrrNVY6OjF|Nke=
GM15850 NGLKV5JMcW6jc3WgRZN{[Xl? MmDvNk42KM7:TR?= M1:1O|k3KGh? NUSwdHNvTE2VTx?= NH\zRW1ld2W|IH7veEBqdmirYnn0JGhFSUNiYYPz[ZN{\WRiYYOgbY5kemWjc3WgbY4hcGm|dH;u[UBJPCCueYPpcoUhOTJiYXPleJlt[XSrb36gc4YhTliQIHflcoU> M3SyPVE3QTJzM{[3
GM15850 MVvLbY5ie2ViQYPzZZk> NU\CbJlwOi53IN88US=> NIXsVHk6PiCq NGSzPHFFVVOR M1z6e4Rw\XNibn;0JIlvcGmkaYSgTGRCSyCjc4Pld5Nm\CCjczDpcoNz\WG|ZTDpckBpcXO2b37lJGg{KGy7c3nu[UA6KGGlZYT5cIF1cW:wIH;mJGZZViCpZX7l MVSxOlkzOTN4Nx?=
GM15850 NVTZVJJuU2mwYYPlJGF{e2G7 MUKyMlUh|ryP M1T2bVk3KGh? NHTHe2JFVVOR NYXRc3BZ\G:nczDuc5QhcW6qaXLpeEBJTEGFIHHzd4V{e2WmIHHzJIlv[3KnYYPlJIlvKGirc4TvcoUhUDRibInzbY5mKDhiYXPleJlt[XSrb36gc4YhTliQIHflcoU> MXyxOlkzOTN4Nx?=
GM15850 MWLLbY5ie2ViQYPzZZk> NIHkdHYzNjVizszN NFPifoI6PiCq MYTEUXNQ M{jJU4Rw\XNibn;0JIlvcGmkaYSgTGRCSyCjc4Pld5Nm\CCjczDpcoNz\WG|ZTDpckBpcXO2b37lJGg1KGy7c3nu[UAyPiCjY3X0fYxifGmxbjDv[kBHYE5iZ3Xu[S=> MV:xOlkzOTN4Nx?=
GM15850 NF7qU21HfW6ldHnvckBCe3OjeR?= NGrFS5Q2KM7:TR?= M3vjXVEzKGh? M4LvRWROW09? NF\5XVBp[XNibn:g[YZn\WO2IH;uJGZZViCvUl7BJIV5eHKnc4Ppc44> NUXQUVFPOTZ7MkGzOlc>
U937 M{fhdmtqdmG|ZTDBd5NigQ>? NY\RN2pSPSEQvF2= MojUNlQhcA>? NGfKemZFVVOR MlO3bIF{KG6xIHXm[oVkfCCxbjDhcJBp[SC2dXL1cIlvKGGlZYT5cIF1cW:w NUe5fHJ1OTd2NEe3OVA>
U937 NGXjTIJMcW6jc3WgRZN{[Xl? MkHrNUDPxE1? MnvONlQhcA>? NUTre3g6TE2VTx?= NVjjcHpIcGG|IH7vJIVn\mWldDDvckBidHCqYTD0eYJ2dGmwIHHj[ZR6dGG2aX;u MYmxO|Q1Pzd3MB?=
PANC1 M{WyPGZ2dmO2aX;uJGF{e2G7 MoL3NUDPxE1? MmrJNlQhcA>? NVjVdVY3\G:nczDuc5QhcW6lcnXhd4UhcW5icEK3b4lxOSCpZX7lJIV5eHKnc4Ppc44> NH3COo4yPzV6OEe0OC=>
PANC1 MlTYSpVv[3Srb36gRZN{[Xl? NGC4TpMyKM7:TR?= MmrYOFghKGh? MXvkc4V{KG6xdDDpcoNz\WG|ZTDpckBxOjetaYCxJIdmdmViZYjwdoV{e2mxbh?= MnvlNVc2QDh5NES=
Caco-2 NYLuVXNJTnWwY4Tpc44hSXO|YYm= M3u1W|Uh|ryP MUKyOEBp MYnEUXNQ NILM[IRld2W|IH7veEBqdmS3Y3WgVFIyX0GIMTDn[Y5mKGW6cILld5Nqd25? NUjGXW1yOjBzNEO4OFA>
SCC4 Mnm3SpVv[3Srb36gRZN{[Xl? NH7oPIkyKM7:TR?= M3fqTlExKG2rbh?= NF7EO5BFVVOR MVToZZMhdm9iYXfvcol{fCCjY4Tpeol1gSCjdDDWSHIh[XO|ZYPz[YQh[XNiaX7keYN1cW:wIH;mJGN[WDJ2IHflcoUh\XiycnXzd4lwdg>? NFi5b3czODR3MkKyOS=>
A549 NXzBbJlNTnWwY4Tpc44hSXO|YYm= NF3XV442KM7:TR?= NF;nPFg{KGh? NGXMcoFFVVOR MUDkc4V{KG6xdDDpcoR2[2ViYYX0c5Bp[We7IHHzd4V{e2WmIHHzJIlv[3KnYYPlJIlvKEyFM1nJ MVeyNFg2PTJyOB?=
HCT116 NEfBcFZMcW6jc3WgRZN{[Xl? NHHx[FcxNjNizszN MoDGN|AhcA>? MlPPSG1UVw>? MUTkc4V{KG6xdDDpcohq[mm2IFjERWMyKGG|c3Xzd4VlKGG|IHnu[JVkfGmxbjDv[kBpcXO2b37lJGg{UzliYXPleJlt[XSrb36= M4fvVlIyODhyNkS3
HepG2 MVTGeY5kfGmxbjDBd5NigQ>? NXXjVFJFOTBizszN NWfFVmFtOjRiaB?= NHm5blBFVVOR MVTkc4V{KG6xdDDpcoR2[2ViYYDvdJRwe2m|IHHzd4V{e2WmIHHzJIh6eGW{YXPleJlt[XSrb36gc4YheDV| M2nsPFIyPTR6NUiy
GM11272 MofHSpVv[3Srb36gRZN{[Xl? MYmwMlEh|ryP MYW3NkBp M4TieGROW09? MYnkc4V{KG6xdDDy[YFkfGm4YYTlJG1mS3B{IH31eIFvfCCneIDy[ZN{cW:w NYWwV29oOjF6NEC3NVY>
MDA-MB-231 M1zmZ2tqdmG|ZTDBd5NigQ>? NGjoSogyOCEQvF2= MX21JI1qdg>? NUjRPIRpTE2VTx?= MkTq[I9meyCwb4SgbY5pcWKrdDDISGFEOmF? NVn5bJhVOjN2OUO0OFk>
MDA-MB-231 MXfLbY5ie2ViQYPzZZk> MX:xJO69VQ>? M{LiRVI1KGh? NH\ZVnNFVVOR MWDkc4V{KG6xdDDpcohq[mm2IFjERWM3KGG|c3Xzd4VlKGG|IHHj[ZR6dGG2aX;uJIxmfmWuczDv[kB1fWK3bHnu M{jCNlI{PDl|NES5
K562 MnrkT4lv[XOnIFHzd4F6 MUPkc4V{KG6xdDDpcohq[mm2IFjERWM> M4iwWlI{PTlzMUGx
Jurkat MW\DfZRwfG:6aXOgRZN{[Xl? M3XqV|IxKM7:TR?= MoX6O|IhcA>? M4XHOWROW09? M3vycI5wKGO7dH;0c5hq[2m2eTDhd5Nme3OnZDDhd{Boem:5dHigbY5pcWKrdHnvci=> NG\0dlkzPDNyNEO0PC=>
HCT116 MVLBdI9xfG:|aYOgRZN{[Xl? NHL1XIY{KM7:TR?= MXGyOEBp M1LHeWROW09? NXuzeZhV\G:nczDuc5QhcW6mdXPlJIFxd3C2b4Ppd{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDwOVMheHKxdHXpckBt\X[nbB?= MljDNlQ4PjZ3NkC=
KASUMI-1 M{fpXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXLJR|UxRTl7LkG3JI5O M13XbHNCVkeHUh?=
KARPAS-45 NEKyWG9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXnJR|UxRTF5Mz64PUBvVQ>? M{LuVHNCVkeHUh?=
BHT-101 NFeyS3NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoTDTWM2OD1{NESuNVghdk1? M3LPNnNCVkeHUh?=
H9 NYfKS2JpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnXITWM2OD1{NUWuNFQhdk1? NYDwdoV7W0GQR1XS
PA-1 M3Lx[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnXwTWM2OD1{OE[uNlYhdk1? NVTUVm5[W0GQR1XS
NEC8 MknES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NW[4SpUyUUN3ME2yPFkvOzhibl2= M3\XcXNCVkeHUh?=
MHH-PREB-1 NGHOfYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnjhTWM2OD1{OUSuOVMhdk1? NGrjfWdUSU6JRWK=
NB7 M4TMbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUXJR|UxRTN2NT63OEBvVQ>? MXvTRW5ITVJ?
A3-KAW MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NE\RWmFKSzVyPUSwNE42QSCwTR?= NYPvcIo1W0GQR1XS
NB69 NV32OIY5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MknXTWM2OD12MUGuO|Ehdk1? NGHzVHBUSU6JRWK=
EoL-1-cell MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkDZTWM2OD12NUSyOUBvVQ>? MofQV2FPT0WU
CHP-212 M3foOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3vEbWlEPTB;NEW3MlU{KG6P NYD5SGRqW0GQR1XS
C2BBe1 NH3pTYVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmnjTWM2OD12N{KuNVkhdk1? NGG2cYVUSU6JRWK=
697 MnHLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoTUTWM2OD12N{OuOFEhdk1? MYDTRW5ITVJ?
BCPAP NGXHdpRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV\JR|UxRTVyMT60NkBvVQ>? NGmyPWdUSU6JRWK=
L-363 NH\WelFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MU\JR|UxRTVyMz6xJI5O MkHhV2FPT0WU
ES8 M2HhfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlTGTWM2OD13MkOuOVMhdk1? MX;TRW5ITVJ?
BE-13 NVG4ZWR1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEjlWpVKSzVyPUWyOk46PiCwTR?= NVPibXVPW0GQR1XS
CTB-1 M2THVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYjJR|UxRTV|Nz65NkBvVQ>? NIrV[mpUSU6JRWK=
HD-MY-Z NGPsU5dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{HmfmlEPTB;NUO4MlE{KG6P MYPTRW5ITVJ?
NKM-1 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVzKTmdTUUN3ME21OFQvOjdibl2= MkGwV2FPT0WU
NCI-H720 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFvqcHZKSzVyPUW2NE4yQCCwTR?= NXPo[mRTW0GQR1XS
KY821 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NULkSGl{UUN3ME21OlMvOjVibl2= NELrbHZUSU6JRWK=
OVCAR-5 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX7YXIp1UUN3ME21O|YvOTFibl2= NVjoZmRrW0GQR1XS
CTV-1 NI\k[HVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIfE[YxKSzVyPUW4NU42PiCwTR?= M3LHeXNCVkeHUh?=
P12-ICHIKAWA MlTwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M17lc2lEPTB;NUm2MlUyKG6P MmOwV2FPT0WU
DB M3vpWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1zRfWlEPTB;NUm4MlU4KG6P NUjrZ41IW0GQR1XS
CHL-1 M3zmWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWnJR|UxRTZ2Mj6wPEBvVQ>? NH25OYJUSU6JRWK=
A4-Fuk M1W2SGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGDo[ZJKSzVyPU[0OE46OSCwTR?= NVPCNHBJW0GQR1XS
MV-4-11 NXywRnkyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYrzV4l3UUN3ME22OVkvOSCwTR?= NXvhRZN1W0GQR1XS
RPMI-8226 NEPHcIVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml3LTWM2OD14N{iuNVghdk1? MV3TRW5ITVJ?
NB14 NFe0VodIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1vtS2lEPTB;Nkm2Mlk2KG6P M2Dh[3NCVkeHUh?=
DOHH-2 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{LsTWlEPTB;N{C2MlY5KG6P MXPTRW5ITVJ?
D-423MG NHO1OWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWDyUItOUUN3ME23NFYvQDlibl2= M37XPHNCVkeHUh?=
D-283MED Mnz5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVfkfnpxUUN3ME23NVQvOTRibl2= MmPkV2FPT0WU
ES1 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoG0TWM2OD15MkSuOEBvVQ>? NVi5W4o5W0GQR1XS
GOTO NVXqbppkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHvvVm9KSzVyPUeyPU4yOiCwTR?= MmPFV2FPT0WU
NCI-H209 M{DBdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVKxSZRLUUN3ME23NlkvQSCwTR?= MlroV2FPT0WU
MOLT-13 MnWzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTd|OD65PEBvVQ>? NUPBSFNDW0GQR1XS
ATN-1 M4OzR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MW\JR|UxRTd2MD6yPEBvVQ>? MlnCV2FPT0WU
DU-4475 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4r1OGlEPTB;N{WxMlkyKG6P MV3TRW5ITVJ?
NB10 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmK0TWM2OD15NUGuPVIhdk1? MXrTRW5ITVJ?
KG-1 Mnv4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{T1SWlEPTB;N{e1MlQ2KG6P NWjKWZY2W0GQR1XS
MOLT-4 NXrISlhUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXiwNVhiUUN3ME23PFcvPDZibl2= NGnueoJUSU6JRWK=
TE-1 M4LHSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1fVWmlEPTB;N{mxMlEhdk1? MXPTRW5ITVJ?
SBC-1 NI\xNolIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn\uTWM2OD15OUOuPFQhdk1? NIHWdFhUSU6JRWK=
HEL MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1zZ[WlEPTB;OEC2MlA5KG6P MnH4V2FPT0WU
SK-MEL-2 NXyxVFZOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4HrbmlEPTB;OEC5MlQ1KG6P NHT3endUSU6JRWK=
KU812 NHPnU2RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2exWGlEPTB;OEGzMlEhdk1? Mn7oV2FPT0WU
RPMI-8866 NHWwOVZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1Kxb2lEPTB;OEGzMlY4KG6P MXHTRW5ITVJ?
ALL-PO Mn32S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnXLTWM2OD16MUSuOlYhdk1? MWnTRW5ITVJ?
LU-139 M{m4NWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXrXN2JMUUN3ME24NlIvQDZibl2= M2G0SnNCVkeHUh?=
RS4-11 NYHudnBZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXHaeIk5UUN3ME24N|IvPDVibl2= M3XHOHNCVkeHUh?=
EW-18 MlvBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mlm5TWM2OD16M{KuPVYhdk1? NETQZmZUSU6JRWK=
P30-OHK Mn;lS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1jnW2lEPTB;OEO1Mlchdk1? NHzUVZVUSU6JRWK=
D-566MG MlOzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXzJR|UxRTh|OD62NkBvVQ>? NEDoNWVUSU6JRWK=
HSC-4 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVnuW5V2UUN3ME24OFYvPTFibl2= MWrTRW5ITVJ?
QIMR-WIL M{DWO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1fBcWlEPTB;OE[yMlA{KG6P MX3TRW5ITVJ?
SW954 MlPGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGW1fYJKSzVyPUi2N{4yPiCwTR?= MXHTRW5ITVJ?
HGC-27 NYnNTo1sT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIjmcndKSzVyPUi3Nk4{PCCwTR?= NHv4RZRUSU6JRWK=
HH M2rP[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYfJR|UxRTh7ND6xNkBvVQ>? MV7TRW5ITVJ?
KE-37 NXjOepdXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXvJR|UxRTh7ND62NkBvVQ>? M{e0fXNCVkeHUh?=
SK-N-DZ MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHrOPI9KSzVyPUmwNE41OyCwTR?= NXHHb2R4W0GQR1XS
J-RT3-T3-5 M3nmTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MULJR|UxRTlzMD60PUBvVQ>? M2rPZnNCVkeHUh?=
A427 NEP5dHNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXnzN4sxUUN3ME25NlAvQDRibl2= NVXrdlVHW0GQR1XS
ECC10 NGjpUWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4jvUWlEPTB;OUS1Mlg4KG6P M1fMeHNCVkeHUh?=
EW-1 NXHTcJpuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUT4XIpGUUN3ME25OFcvOjZibl2= NYi1TYZoW0GQR1XS
MIA-PaCa-2 NYrjU2piT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYGzOI1jUUN3ME25OFkvOTJibl2= NHy0WJdUSU6JRWK=
HCC2218 NWD6ZnVwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlnCTWM2OD17NUiuOFghdk1? Moe5V2FPT0WU
HAL-01 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1e4N2lEPTB;OU[4MlA1KG6P NVfnWoN1W0GQR1XS
RD NEXvWoVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXjIWYhCUUN3ME25O|QvPDVibl2= NHHtdZBUSU6JRWK=
SK-N-AS MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlmzTWM2OD17OEiuNUBvVQ>? NHviT2FUSU6JRWK=
ML-2 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWjJR|UxRTFwMEC0NFch|ryP MYTTRW5ITVJ?
MEL-HO MoLqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlvqTWM2OD1zLkCwOVgzKM7:TR?= MX;TRW5ITVJ?
MS-1 NGP5TmRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnuwTWM2OD1zLkCwOlE4KM7:TR?= MlywV2FPT0WU
NCI-SNU-1 NV3LSoYzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYfJR|UxRTFwMEKzN|Eh|ryP NWXmfmIxW0GQR1XS
8505C NXnRZ3FkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVT0RZdGUUN3ME2xMlAzOzNzIN88US=> MoX4V2FPT0WU
MN-60 NGnxe2tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NW[yPFU4UUN3ME2xMlAzPjhizszN MmLNV2FPT0WU
SAS NF;W[25Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV7F[YE{UUN3ME2xMlA1ODhzIN88US=> MXTTRW5ITVJ?
EFM-19 Mny5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1;4TWlEPTB;MT6wOFg4QSEQvF2= M3fhbnNCVkeHUh?=
Ca9-22 M1jMVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoDiTWM2OD1zLkC1NVA4KM7:TR?= NVrXbGk4W0GQR1XS
NBsusSR MnvMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1zYVGlEPTB;MT6wOVE3PiEQvF2= MYHTRW5ITVJ?
NB13 NXq0OYxDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIfXS3dKSzVyPUGuNFU2ODFizszN NEnTcJpUSU6JRWK=
SF295 NYi2b4x2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlvKTWM2OD1zLkC2OlI1KM7:TR?= NIPCSoRUSU6JRWK=
U-2-OS NFT4[oxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnTyTWM2OD1zLkC3PVEyKM7:TR?= NWTuNmlPW0GQR1XS
NCI-H526 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3rS[GlEPTB;MT6wPFI6OSEQvF2= M3mwbHNCVkeHUh?=
KMOE-2 NIjlfm5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXLJR|UxRTFwMEm0NlIh|ryP MnfEV2FPT0WU
RCM-1 MnPOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYTzVZRlUUN3ME2xMlEzOTB{IN88US=> NV\uPXdzW0GQR1XS
MC116 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVLJR|UxRTFwMUO2NlEh|ryP M17qeHNCVkeHUh?=
NCI-H1092 MmDRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn63TWM2OD1zLkG1OFA3KM7:TR?= MmTBV2FPT0WU
EW-3 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2K1WGlEPTB;MT6xO|IyOiEQvF2= NUfqUIxjW0GQR1XS
HCT-116 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVjJR|UxRTFwMUe3OUDPxE1? M{LES3NCVkeHUh?=
MC-IXC M4fRfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3XRPGlEPTB;MT6xO|g5OSEQvF2= M{HLbHNCVkeHUh?=
LB1047-RCC M3PmfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVnJR|UxRTFwMUizNVIh|ryP MonoV2FPT0WU
VM-CUB-1 MoTaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYfDVGVuUUN3ME2xMlE6OTB6IN88US=> NVrQT3NnW0GQR1XS
NB5 MmPpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVPJR|UxRTFwMUm4OVYh|ryP Ml\qV2FPT0WU
SKG-IIIa M1;pSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGi3XnVKSzVyPUGuNlM1PjRizszN M3PZOnNCVkeHUh?=
HO-1-N-1 M{XtVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnjVTWM2OD1zLkKzPFM2KM7:TR?= NXTOTHJxW0GQR1XS
EFO-27 M3XlTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGC0U4FKSzVyPUGuNlUxPDNizszN MonhV2FPT0WU
MHH-NB-11 NUPmU3BsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3jUPGlEPTB;MT6yPFMzQSEQvF2= M1Sy[3NCVkeHUh?=
SW620 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFy1cVRKSzVyPUGuNlkxOThizszN MWHTRW5ITVJ?
MOLT-16 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4nNS2lEPTB;MT6yPVc6PyEQvF2= MXPTRW5ITVJ?
NTERA-S-cl-D1 M1\6b2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVLJR|UxRTFwM{G3OlEh|ryP NFrqVFlUSU6JRWK=
VA-ES-BJ MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1vDVGlEPTB;MT6zNlQ4PyEQvF2= M2DlXHNCVkeHUh?=
HCC1419 M{XqSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml7XTWM2OD1zLkO0NFI4KM7:TR?= NWHON|lYW0GQR1XS
NCI-H69 NYTOTYQ3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUPJR|UxRTFwM{SxNVIh|ryP MnrQV2FPT0WU
DEL Mn7sS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFH6Rm9KSzVyPUGuN|UyPjJizszN M3WzPHNCVkeHUh?=
LXF-289 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{LB[mlEPTB;MT6zOVI1KM7:TR?= NV\JSHZEW0GQR1XS
EW-11 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXfJR|UxRTFwM{[wNlYh|ryP M2[1THNCVkeHUh?=
KP-4 MnzHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVXJR|UxRTFwM{ewPFUh|ryP Ml\4V2FPT0WU
NOS-1 NGixd2VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmHiTWM2OD1zLkSxNVk1KM7:TR?= MXHTRW5ITVJ?
SK-NEP-1 NF[xe5FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGW0dHZKSzVyPUGuOFE3QTNizszN MnvyV2FPT0WU
LAMA-84 NF[zSpFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWT1[XB1UUN3ME2xMlQ{QTR3IN88US=> MVzTRW5ITVJ?
ES5 M3H5[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnLSTWM2OD1zLkS0N{DPxE1? NIW3OGFUSU6JRWK=
HuO9 NF;tbWJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NU\s[GVnUUN3ME2xMlQ2OzZ{IN88US=> MnflV2FPT0WU
COLO-684 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3HucmlEPTB;MT60OlEyQCEQvF2= NH\wSoFUSU6JRWK=
EW-24 MoLQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXXJR|UxRTFwNE[1N|Eh|ryP MnTpV2FPT0WU
BV-173 M4\kUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUPJR|UxRTFwNEeyPVEh|ryP NF24U4NUSU6JRWK=
NCI-H1770 NILaRnFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlOzTWM2OD1zLkS4OVM3KM7:TR?= MUfTRW5ITVJ?
HuP-T4 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGnwbZVKSzVyPUGuOFk{KM7:TR?= NHTN[YJUSU6JRWK=
TYK-nu M1T1RWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEPkZ3VKSzVyPUGuOFk5PTFizszN MWrTRW5ITVJ?
YH-13 Mk\NS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUjJR|UxRTFwNEm4PVQh|ryP MlWwV2FPT0WU
H4 M{[3dWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUXJR|UxRTFwNUC5NVIh|ryP M1;kU3NCVkeHUh?=
OVCAR-8 NYS5e5VwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2nxOGlEPTB;MT61OFQ4PyEQvF2= MYLTRW5ITVJ?
NCI-H23 Mn\PS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXPlW2RMUUN3ME2xMlU1PjR3IN88US=> M4nTWHNCVkeHUh?=
ES7 NUmzT2lIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYjJR|UxRTFwNUS3O|Mh|ryP MliyV2FPT0WU
COR-L88 MnfDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnHyTWM2OD1zLkW2OFI1KM7:TR?= NFX1cmhUSU6JRWK=
TI-73 MkDhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NI\QfW9KSzVyPUGuOVkxPiEQvF2= NYjIPZo5W0GQR1XS
RT-112 MojmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUnJR|UxRTFwNUmyPFQh|ryP NXX6R21CW0GQR1XS
HuO-3N1 NELJS2hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX3JR|UxRTFwNUmzPFUh|ryP M{XZZnNCVkeHUh?=
HC-1 Mkn3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlW3TWM2OD1zLkW5PFY3KM7:TR?= NWXoVmt4W0GQR1XS
HT55 NW\teXpqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVuxXm86UUN3ME2xMlY2OTNzIN88US=> M4TIR3NCVkeHUh?=
IA-LM NUjIPYJbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4nRWmlEPTB;MT62PVI4QCEQvF2= MmfBV2FPT0WU
EM-2 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHTGWGtKSzVyPUGuO|AxOTRizszN NVX1WIVxW0GQR1XS
MHH-ES-1 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWHJR|UxRTFwN{C0N|Uh|ryP NWLufVY5W0GQR1XS
CAL-27 NW[3Z5g1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGfZS4dKSzVyPUGuO|A3OjFizszN M4X1S3NCVkeHUh?=
COLO-800 NY\Z[os2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnjFTWM2OD1zLkexNVc6KM7:TR?= NYDLUpptW0GQR1XS
HCE-T MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXT6OIFFUUN3ME2xMlcyPSEQvF2= MYPTRW5ITVJ?
CAMA-1 MoXQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mm\WTWM2OD1zLkexPVcyKM7:TR?= NYjBXJZWW0GQR1XS
LOXIMVI M{i1Z2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1P3UWlEPTB;MT63NlEyKM7:TR?= Mk[zV2FPT0WU
NH-12 NET6XXJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlTlTWM2OD1zLkeyOlkyKM7:TR?= MknmV2FPT0WU
TCCSUP NWW0W5VkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2PJZmlEPTB;MT63NlgzQSEQvF2= M2nrVHNCVkeHUh?=
MDA-MB-361 NYTzdFlbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkT0TWM2OD1zLkezNVU4KM7:TR?= NH70d29USU6JRWK=
EW-16 M371Nmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEfYW4VKSzVyPUGuO|QyODdizszN MnLWV2FPT0WU
SNU-423 NF7pVI5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3XkXmlEPTB;MT63OVgzPyEQvF2= Mn:3V2FPT0WU
Daoy NGrl[5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NETXV2dKSzVyPUGuO|Y{OTlizszN NXvBNJY5W0GQR1XS
ES4 M1jzbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NY\TXYhCUUN3ME2xMlc5PzRzIN88US=> M2ToS3NCVkeHUh?=
PFSK-1 MnyyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{XUTGlEPTB;MT64NFM4KM7:TR?= NHy4ZnJUSU6JRWK=
ES3 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUHJR|UxRTFwOEK2PFEh|ryP MV\TRW5ITVJ?
ONS-76 NXPqfJRxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYfJR|UxRTFwOEK4PVch|ryP MoTPV2FPT0WU
JVM-3 NFLGPJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2DRc2lEPTB;MT64OVQ2OSEQvF2= NG\lfFBUSU6JRWK=
OS-RC-2 M4HmZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVfGXVRSUUN3ME2xMlg4OTVzIN88US=> NWXjNIVQW0GQR1XS
COLO-320-HSR M2nwXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYPJR|UxRTFwOEixPVch|ryP NH7EZnpUSU6JRWK=
HN NIqzRWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHjmVmhKSzVyPUGuPFg4OjVizszN M4PxbHNCVkeHUh?=
HT NEfabJRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWfLRoJpUUN3ME2xMlg5QTR5IN88US=> M4jCWnNCVkeHUh?=
LoVo MmrLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4PBNGlEPTB;MT64PVgyKM7:TR?= MkXvV2FPT0WU
CGTH-W-1 NFnsV|hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUfOTnVGUUN3ME2xMlg6QTR4IN88US=> MVnTRW5ITVJ?
NB6 NXn6bJNlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHiyVYFKSzVyPUGuPVEzQThizszN MlnFV2FPT0WU
EW-22 NFzRTJpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXXSSpRGUUN3ME2xMlkzQDh5IN88US=> MoOxV2FPT0WU
ES6 NWjmcJM5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUD1fnNzUUN3ME2xMlk{PjNzIN88US=> MUDTRW5ITVJ?
SCC-15 M2\ybWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2PieWlEPTB;MT65N|gyQSEQvF2= MnTwV2FPT0WU
HL-60 M1fmemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYi2OpNpUUN3ME2xMlk{QTB{IN88US=> NVfrR2dCW0GQR1XS
human HOP-92 M1WxeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYfJR|UxRTFwOUSwOlUh|ryP MVPTRW5ITVJ?
SW626 M2DXT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{LEdWlEPTB;MT65OFg6QSEQvF2= M{mxXnNCVkeHUh?=
HEC-1 MlfMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGq2R25KSzVyPUGuPVU{PiEQvF2= MWnTRW5ITVJ?
LB2241-RCC M4PYXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEjvfXBKSzVyPUGuPVgzOzFizszN MoKxV2FPT0WU
Ramos-2G6-4C10 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYmyfokzUUN3ME2xMlk6PDl|IN88US=> M3fMbnNCVkeHUh?=
A101D NHfNWYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3PYfWlEPTB;Mj6yNFMxOyEQvF2= MXTTRW5ITVJ?
NCI-H446 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXnOOJB{UUN3ME2yMlA1PTl7IN88US=> MWHTRW5ITVJ?
SBC-5 NYjEU4lUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnP3TWM2OD1{LkC2NVQ4KM7:TR?= MXHTRW5ITVJ?
HOS MmrCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mm\FTWM2OD1{LkC3OlU{KM7:TR?= MWfTRW5ITVJ?
K5 NXGwWnJvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkDuTWM2OD1{LkC3PFEyKM7:TR?= MkHHV2FPT0WU
HLE MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn23TWM2OD1{LkC4OVI6KM7:TR?= NH62SoNUSU6JRWK=
HSC-2 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnG1TWM2OD1{LkGyPFk5KM7:TR?= NIfwNZZUSU6JRWK=
LCLC-97TM1 M4Dvbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHG5bnNKSzVyPUKuNVQ2QDNizszN MXPTRW5ITVJ?
DMS-273 NUnQTnI2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV;JR|UxRTJwMUS4N|ch|ryP NFLD[phUSU6JRWK=
TE-8 NF[3cWpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3q4UGlEPTB;Mj6xOVc3PSEQvF2= Ml;mV2FPT0WU
DSH1 MlLFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn\MTWM2OD1{LkG2N|k5KM7:TR?= NXPIUnVyW0GQR1XS
CAL-51 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml\VTWM2OD1{LkG2Olk6KM7:TR?= NYP1VlZlW0GQR1XS
IST-SL1 Mmm3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MULJR|UxRTJwMU[4OFQh|ryP NG\RNnpUSU6JRWK=
GCT MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnXITWM2OD1{LkG3O|ch|ryP NYPQZWI4W0GQR1XS
SW948 NVjzS|I3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4r3SGlEPTB;Mj6xPFQ2PiEQvF2= Mnn1V2FPT0WU
NOMO-1 M4HZUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXLJR|UxRTJwMUmzNVch|ryP Ml3HV2FPT0WU
C8166 MomzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1TPPGlEPTB;Mj6yNVM{PCEQvF2= NFewUHdUSU6JRWK=
OC-314 MnHtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2TLOWlEPTB;Mj6yN|I2QSEQvF2= M1r5WHNCVkeHUh?=
CAL-39 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVe1XVQ1UUN3ME2yMlI{PjJ4IN88US=> M2XGd3NCVkeHUh?=
MDA-MB-453 Mof6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NELNbGJKSzVyPUKuNlQzPzVizszN MVjTRW5ITVJ?
A673 NELtVGpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWHkc4pWUUN3ME2yMlI2QDZ{IN88US=> MkP4V2FPT0WU
HTC-C3 MkWyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkDhTWM2OD1{LkK2PFUh|ryP NF;wXllUSU6JRWK=
NCI-H1666 NX7XOYllT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWfJfXlVUUN3ME2yMlI5OTFzIN88US=> MYrTRW5ITVJ?
PSN1 NFjIVoZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVToNYo{UUN3ME2yMlI5QTF|IN88US=> M16yfHNCVkeHUh?=
GI-1 NWXV[lNUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIe1UGZKSzVyPUKuN|A2PDNizszN NX\YR3BvW0GQR1XS
HuH-7 M4P1Smdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MonYTWM2OD1{LkOwOlM4KM7:TR?= MnXyV2FPT0WU
JAR M1vWfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXvJR|UxRTJwM{G5PFch|ryP NFO1bYpUSU6JRWK=
5637 MoPmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mm\PTWM2OD1{LkOyNVI6KM7:TR?= MWnTRW5ITVJ?
GB-1 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX3JR|UxRTJwM{KzN|Uh|ryP NI[2flBUSU6JRWK=
KP-N-YS MnexS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3HsbmlEPTB;Mj6zNlYyPSEQvF2= NE[x[HhUSU6JRWK=
OAW-42 MnnqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWnJR|UxRTJwM{O0NVYh|ryP M4L2PHNCVkeHUh?=
8-MG-BA MmTnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1PzUmlEPTB;Mj6zN|kxPiEQvF2= M2HqTHNCVkeHUh?=
RH-18 NIXyVZZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXPJR|UxRTJwM{WwNlIh|ryP M3m2[HNCVkeHUh?=
NCI-H1155 M2G4d2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGr1S3RKSzVyPUKuN|Y4OjVizszN MUTTRW5ITVJ?
NB17 NGjpTppIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUeyTIZiUUN3ME2yMlM5OjR|IN88US=> NIr0U3BUSU6JRWK=
NCI-H1437 M2DzXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWnJR|UxRTJwNEG4O|Mh|ryP MlvnV2FPT0WU
SN12C M4LZdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4nrUGlEPTB;Mj60N|IyPCEQvF2= NXfwSIVvW0GQR1XS
HSC-3 M2izeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWnBeIFMUUN3ME2yMlQ1PTB7IN88US=> M4r3e3NCVkeHUh?=
GAMG NYj0ZmVXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4TCPGlEPTB;Mj60OFU3OSEQvF2= NEK0[I1USU6JRWK=
HT-1080 NG\i[3JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFfac|BKSzVyPUKuOFQ5PjRizszN Mk\lV2FPT0WU
A549 NWfrZ5FST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M372c2lEPTB;Mj60OFg6OyEQvF2= M{PvV3NCVkeHUh?=
KNS-62 MlvZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV76S4VxUUN3ME2yMlQ2ODZzIN88US=> MnLGV2FPT0WU
YKG-1 NHT6TWVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV7JR|UxRTJwNEW0N|ch|ryP MVfTRW5ITVJ?
LU-134-A NEnNXlFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYXpfoVjUUN3ME2yMlQ4ODB6IN88US=> MnfHV2FPT0WU
FADU Mk\KS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIrOWJlKSzVyPUKuOFcyPjJizszN MVrTRW5ITVJ?
TGBC11TKB MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX\JR|UxRTJwNEexO|ch|ryP NXjyeG5yW0GQR1XS
HT-3 Mn;MS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2jCTGlEPTB;Mj60PVU{PSEQvF2= MWnTRW5ITVJ?
NCI-H2170 NGSxWZNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFTZUotKSzVyPUKuOVA2PDlizszN MV;TRW5ITVJ?
Mo-T Mn6yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXHGOnBIUUN3ME2yMlUxQTJ5IN88US=> NGrZOINUSU6JRWK=
CCRF-CEM MkTSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVfJR|UxRTJwNUOwOFMh|ryP M2PSRXNCVkeHUh?=
KU-19-19 NYHlcm9KT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX2xdXNTUUN3ME2yMlU{PTF|IN88US=> NXLZXHVsW0GQR1XS
NCI-H1048 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUfJR|UxRTJwNUWwNlUh|ryP MWjTRW5ITVJ?
KOSC-2 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{nHTWlEPTB;Mj61OlA4PiEQvF2= NWXCPYZwW0GQR1XS
A431 M4OwTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoPkTWM2OD1{LkW2N|M2KM7:TR?= MkL5V2FPT0WU
COR-L23 NHSwXYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{HB[2lEPTB;Mj61PFU3PiEQvF2= NHSwdI9USU6JRWK=
MKN28 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmPaTWM2OD1{LkW5NFM4KM7:TR?= MmXEV2FPT0WU
22RV1 MmXDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlXOTWM2OD1{LkW5Nlc1KM7:TR?= MXvTRW5ITVJ?
ABC-1 NV3yXZVoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MW\JR|UxRTJwNkC0OkDPxE1? MV\TRW5ITVJ?
NCI-H2126 MojkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoHLTWM2OD1{Lk[wPVg1KM7:TR?= Mn;OV2FPT0WU
DoTc2-4510 M{P5OWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkHmTWM2OD1{Lk[yNVg2KM7:TR?= NF:wfXdUSU6JRWK=
SCC-4 Mm\NS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mkm1TWM2OD1{Lk[zNFEzKM7:TR?= M4\jdXNCVkeHUh?=
NCI-H661 NVzVdJVOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4LSZ2lEPTB;Mj62OFA5PSEQvF2= NUT6TJFPW0GQR1XS
RPMI-2650 NGHTcWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkfNTWM2OD1{Lk[0NVQ{KM7:TR?= MUHTRW5ITVJ?
NCI-H510A NWPIT|FHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWDEN49yUUN3ME2yMlY1PDJ4IN88US=> NVvRSpdvW0GQR1XS
BPH-1 NHTzPYVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGriXYpKSzVyPUKuOlU5PSEQvF2= M3PtOXNCVkeHUh?=
M14 NXO3bGx6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXrJR|UxRTJwNk[5PVMh|ryP Mo\zV2FPT0WU
G-402 M3XObGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX\JR|UxRTJwN{C0OVEh|ryP M4\id3NCVkeHUh?=
AsPC-1 MnT6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVThXIVKUUN3ME2yMlcyOTdizszN MX\TRW5ITVJ?
NB12 MmTIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3;pWmlEPTB;Mj63NVcyKM7:TR?= MWPTRW5ITVJ?
SK-HEP-1 MlfUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUDsT29VUUN3ME2yMlc1OzlzIN88US=> MnnjV2FPT0WU
U-266 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NULKSFlYUUN3ME2yMlc4OTJzIN88US=> M1zBdHNCVkeHUh?=
AM-38 NVrTRYZxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHPGSpRKSzVyPUKuO|c{PTVizszN NVzmdYwxW0GQR1XS
PC-14 M4TUXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmHtTWM2OD1{LkiwOVEh|ryP MXnTRW5ITVJ?
EGI-1 NEfXN21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1rDXWlEPTB;Mj64NVc1OyEQvF2= M1nTSHNCVkeHUh?=
LS-411N M2XsUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEPocJRKSzVyPUKuPFI{OyEQvF2= Mn7HV2FPT0WU
BFTC-905 NXTyTWV3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NE\oVJlKSzVyPUKuPFU2OjNizszN MoHkV2FPT0WU
CaR-1 M1PzO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmjKTWM2OD1{Lki2JO69VQ>? Mom0V2FPT0WU
NCI-H292 NIDnfZNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml7tTWM2OD1{Lki2OVk3KM7:TR?= NWj1TlNYW0GQR1XS
8305C MoLwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVrJR|UxRTJwOE[2OFUh|ryP NIO1dJNUSU6JRWK=
SNU-449 NGfvbpBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWPlUWpoUUN3ME2yMlg6OTh{IN88US=> NF7Wd3FUSU6JRWK=
LCLC-103H MoH6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnezTWM2OD1{LkmwOFM5KM7:TR?= MlvVV2FPT0WU
SW1573 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlH4TWM2OD1{Lkm2NFgzKM7:TR?= MnXkV2FPT0WU
MLMA M3\oTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXjJR|UxRTJwOU[3NVch|ryP NWfl[lF{W0GQR1XS
NCI-H1355 MnnOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4P1NmlEPTB;Mz6wNFc6PiEQvF2= NGrjVVlUSU6JRWK=
RMG-I Mn20S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkLkTWM2OD1|LkCyOVkzKM7:TR?= NGW0SIpUSU6JRWK=
BB65-RCC MmH3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVjJR|UxRTNwMEOzNVQh|ryP MlS1V2FPT0WU
PC-3 NHqxOYxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEXMPHJKSzVyPUOuNFM5PzRizszN MlTpV2FPT0WU
SF268 MlThS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmrJTWM2OD1|LkC0OVI{KM7:TR?= M1XzfHNCVkeHUh?=
NCI-H810 M3H3TGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlXPTWM2OD1|LkC0PFI{KM7:TR?= MljyV2FPT0WU
MEG-01 NVS2Um9YT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXnJR|UxRTNwME[xOlQh|ryP Ml3nV2FPT0WU
SW13 M365Rmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1T6PWlEPTB;Mz6wO|g1PyEQvF2= M{PV[XNCVkeHUh?=
RH-1 NF[3b45Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{Ljd2lEPTB;Mz6xNFI4QCEQvF2= M3ryd3NCVkeHUh?=
GT3TKB M1;ufGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{HobmlEPTB;Mz6xNVI5OyEQvF2= MmnQV2FPT0WU
TK10 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXvJR|UxRTNwMUO3NlQh|ryP MnnYV2FPT0WU
T-24 NXjH[Y5CT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnO3TWM2OD1|LkG1NFch|ryP NH3rdXNUSU6JRWK=
A498 NXzabXJ3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYHJR|UxRTNwMkC4O|Eh|ryP NV\PdWppW0GQR1XS
GR-ST NWHvV4VFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYj3SVE6UUN3ME2zMlIzOTN7IN88US=> NEG4c4lUSU6JRWK=
LB2518-MEL NHfXZ4ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX;JR|UxRTNwMkKzPVgh|ryP MYLTRW5ITVJ?
T47D M1zDcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkHuTWM2OD1|LkKzOlI4KM7:TR?= M{G4ZnNCVkeHUh?=
NCI-H1651 M1jLN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MULJR|UxRTNwMkS2OFQh|ryP MmHJV2FPT0WU
EC-GI-10 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVnJR|UxRTNwMk[xOVMh|ryP NF3mUGFUSU6JRWK=
HT-29 M2HVU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYS2TYRQUUN3ME2zMlI3PjF2IN88US=> MoTtV2FPT0WU
GI-ME-N MkLCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2T6bWlEPTB;Mz6yPVUyOSEQvF2= MYLTRW5ITVJ?
SW756 NWfrVGUzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFXDc|FKSzVyPUOuNlk3OjlizszN MVvTRW5ITVJ?
RKO NYfjdIp3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NITEO45KSzVyPUOuN|A4PTdizszN MXzTRW5ITVJ?
NCI-H1563 NFW2Z45Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2nGSGlEPTB;Mz6zN|AyQCEQvF2= MUXTRW5ITVJ?
DJM-1 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVe1NJdEUUN3ME2zMlM4Pjd2IN88US=> NFXK[VJUSU6JRWK=
L-428 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MofFTWM2OD1|LkSwNFQ2KM7:TR?= MlfmV2FPT0WU
NCI-H2122 MkLYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoG3TWM2OD1|LkSxN|EzKM7:TR?= MnvsV2FPT0WU
Ca-Ski MkfMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVzyfYdSUUN3ME2zMlQ2PDNizszN MYTTRW5ITVJ?
639-V MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGLtZVFKSzVyPUOuOFYxPTdizszN MW\TRW5ITVJ?
SW1116 M3LEVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGPRNmpKSzVyPUOuOFYzPjlizszN MUXTRW5ITVJ?
DMS-114 NFT1RZlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmDZTWM2OD1|LkS3NFY3KM7:TR?= MXPTRW5ITVJ?
MZ2-MEL M2jmbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH\ycmFKSzVyPUOuOFc3QDFizszN NFzIOZhUSU6JRWK=
COLO-829 MmD2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV;YXZJsUUN3ME2zMlUxODd|IN88US=> MkfBV2FPT0WU
J82 MoDnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWrp[4pUUUN3ME2zMlUxPTdizszN MknOV2FPT0WU
EW-13 MnG2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIPmO5ZKSzVyPUOuOVI2OSEQvF2= M4KxbnNCVkeHUh?=
RXF393 NXTSWpptT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXGxWVdzUUN3ME2zMlU{Ojl2IN88US=> MlfkV2FPT0WU
CAL-62 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4HyfGlEPTB;Mz61OFUyPCEQvF2= M4n0SXNCVkeHUh?=
OCUB-M NEnMb4FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHv4SGNKSzVyPUOuOVQ3PjVizszN MYDTRW5ITVJ?
BT-474 NWjqeFBZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIjBZpBKSzVyPUOuOlM{OSEQvF2= NXflU5JCW0GQR1XS
KYSE-180 M3\jeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVfLNllXUUN3ME2zMlY{Ozd{IN88US=> MlXKV2FPT0WU
NCI-H650 MnTaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV76bItPUUN3ME2zMlY1Ojh5IN88US=> M3zx[3NCVkeHUh?=
Detroit562 MljRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn;WTWM2OD1|Lk[1NFIzKM7:TR?= MUjTRW5ITVJ?
SW48 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFXpcGpKSzVyPUOuOlU3PTdizszN M2P2fnNCVkeHUh?=
KYSE-450 MnzvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml35TWM2OD1|Lk[4OVgzKM7:TR?= M1rSTHNCVkeHUh?=
KYSE-510 MorRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUHJR|UxRTNwN{KxPFEh|ryP MXfTRW5ITVJ?
GP5d M1TaVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV7JR|UxRTNwN{K5OUDPxE1? MnvPV2FPT0WU
RPMI-7951 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGLxd2hKSzVyPUOuO|Q4OjNizszN MmnVV2FPT0WU
Becker NEnrdFhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mm[xTWM2OD1|Lke1NFEzKM7:TR?= M3G2XnNCVkeHUh?=
WM-115 Moq1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHXtVZVKSzVyPUOuO|gyQTVizszN MWTTRW5ITVJ?
G-401 NEDFcmRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkfoTWM2OD1|Lke5NFg2KM7:TR?= MlG4V2FPT0WU
PANC-08-13 M2W3PWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M37vSmlEPTB;Mz63PVYxOiEQvF2= NUO0UXNYW0GQR1XS
SW982 NH;2O3BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF\HOXFKSzVyPUOuPFA2PTFizszN M4D1bnNCVkeHUh?=
D-263MG MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn7nTWM2OD1|LkiyNFUyKM7:TR?= MoDEV2FPT0WU
KM-H2 M{fMSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXjJR|UxRTNwOEK2NlQh|ryP MoTKV2FPT0WU
SK-MEL-3 M4m4UGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVzjTYw1UUN3ME2zMlgzQDRzIN88US=> NF;GdJJUSU6JRWK=
NCI-H1581 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYfJR|UxRTNwOES0PFgh|ryP NFz3XWlUSU6JRWK=
LS-123 M3vnS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2XidGlEPTB;Mz64O|kxQSEQvF2= NXrScGV4W0GQR1XS
CAKI-1 MnnWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF3NNnhKSzVyPUOuPFkxPTJizszN NXPDeXliW0GQR1XS
MEL-JUSO M4LwTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUf2WlU1UUN3ME2zMlg6OTV|IN88US=> MVLTRW5ITVJ?
HCE-4 NYG4eG5QT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF\JVJJKSzVyPUOuPVE3PjNizszN MnG1V2FPT0WU
TE-10 Mk[0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVLJR|UxRTNwOUKwNUDPxE1? Mn3iV2FPT0WU
OVCAR-4 NUPScHEzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkjUTWM2OD1|LkmyPFg6KM7:TR?= NWP1RXFFW0GQR1XS
ETK-1 NIT6dZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEPsVJdKSzVyPUOuPVQ3OzVizszN NIX3WlBUSU6JRWK=
A2780 NEHUXW9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHS3O4lKSzVyPUSuNFU6PjZizszN NE\TT3pUSU6JRWK=
LU-65 NWr4WVlqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHr1dolKSzVyPUSuNFc3OzNizszN M4LpXnNCVkeHUh?=
BHY M3nGOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3;NcGlEPTB;ND6xNlQ6PSEQvF2= MVTTRW5ITVJ?
COR-L105 Mn:zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVPJR|UxRTRwMUOwOVEh|ryP M1[3S3NCVkeHUh?=
CAL-12T MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWLJR|UxRTRwMUOxNFMh|ryP NUCwNGNpW0GQR1XS
SCH NV:2WIR6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkD4TWM2OD12LkG1O|Q{KM7:TR?= MoPvV2FPT0WU
CW-2 M4DvUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVnJR|UxRTRwMUmwNFEh|ryP MoHSV2FPT0WU
HCC1806 NGjpdFNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWnid2htUUN3ME20MlIxOzF{IN88US=> NGHIOnJUSU6JRWK=
KP-N-YN M1TaSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlrPTWM2OD12LkKwPVI4KM7:TR?= NV\rdIlKW0GQR1XS
T98G MmjuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVTPS5k6UUN3ME20MlIzOTV5IN88US=> MmfFV2FPT0WU
CAL-54 NULvU|dmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXHJR|UxRTRwMkKzPFEh|ryP MUXTRW5ITVJ?
CAL-33 NYfvTYNvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MojuTWM2OD12LkKzNFY1KM7:TR?= NXi1cI82W0GQR1XS
SNU-C2B M{Oz[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVPJR|UxRTRwMkS3Olkh|ryP MmX0V2FPT0WU
NUGC-3 M1j2c2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlrpTWM2OD12LkK1OVA2KM7:TR?= MnLjV2FPT0WU
DOK M1HaV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVPLSmF3UUN3ME20MlI3PTl|IN88US=> MVPTRW5ITVJ?
MMAC-SF NXzJeXRpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUTQblJoUUN3ME20MlI3QDV7IN88US=> NFHXPG9USU6JRWK=
KYSE-70 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYHJR|UxRTRwMkmzOEDPxE1? MmTLV2FPT0WU
A204 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUnJR|UxRTRwM{W4NFMh|ryP NXntRVJuW0GQR1XS
SCC-25 NH3GbpBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoXTTWM2OD12LkO1PFE6KM7:TR?= NVPRcYVEW0GQR1XS
EPLC-272H MnHPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1\NNmlEPTB;ND6zPFk2KM7:TR?= Mmi3V2FPT0WU
CAL-120 M1;ZO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUT5THh1UUN3ME20MlM5QTl{IN88US=> NWXxfphIW0GQR1XS
LS-513 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEHEVG5KSzVyPUSuOFIyQThizszN NGDIXVZUSU6JRWK=
CAPAN-1 NHr3PIpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH;0NmJKSzVyPUSuOFI{QDJizszN MlK2V2FPT0WU
ESS-1 NXLvV3U3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mm[1TWM2OD12LkSyO|I1KM7:TR?= NXjSPYRDW0GQR1XS
GMS-10 MnrWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIP5O4JKSzVyPUSuOFI5OTlizszN M1LGTHNCVkeHUh?=
NCI-N87 NVHZfmZUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{XzZ2lEPTB;ND61NFg3QCEQvF2= NWrPWpZiW0GQR1XS
HMV-II NELRNFBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUD2VIZkUUN3ME20MlUyPzNizszN MnGxV2FPT0WU
COLO-741 MoeyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWGzZ41pUUN3ME20MlU2QTl2IN88US=> MWLTRW5ITVJ?
MKN45 NWrBO5c4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXXqVVJ7UUN3ME20MlU4PzN{IN88US=> MVzTRW5ITVJ?
OAW-28 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV;6TYY4UUN3ME20MlU5Ozl6IN88US=> MVzTRW5ITVJ?
OCI-AML2 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHzpWWhKSzVyPUSuOlUzOzhizszN MWLTRW5ITVJ?
MDA-MB-231 NHHVV29Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYHJR|UxRTRwN{CyOFMh|ryP NUG0NlQ4W0GQR1XS
NCI-H1648 MlfES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWnDcJVPUUN3ME20MlczOjd|IN88US=> MorlV2FPT0WU
NCI-H1792 NVrYNIZnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{Ps[mlEPTB;ND63OlExPyEQvF2= MYTTRW5ITVJ?
GCIY NIHzcXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4\XS2lEPTB;ND63O|QzPCEQvF2= MojxV2FPT0WU
Hs-578-T MmX0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXfJR|UxRTRwN{e2OVUh|ryP MW\TRW5ITVJ?
SW962 MmnES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mor4TWM2OD12Lke4NFEyKM7:TR?= NGPMV49USU6JRWK=
NCI-H630 NViwR4F{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXHJR|UxRTRwN{iwPFEh|ryP Mnr5V2FPT0WU
786-0 Mn:3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlnQTWM2OD12Lke4O|c{KM7:TR?= M{LCO3NCVkeHUh?=
FTC-133 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGH3U3hKSzVyPUSuO|kzPjNizszN MmXNV2FPT0WU
BT-20 NFjIWZBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEfRTFlKSzVyPUSuO|k1OjlizszN M2XqSnNCVkeHUh?=
Mewo NVTNTYoyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYfJR|UxRTRwOEG3OFch|ryP M2GyTHNCVkeHUh?=
SW780 NYrXUo92T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUPt[Yp4UUN3ME20Mlg2PzZ4IN88US=> M4PxUHNCVkeHUh?=
OE33 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4jjcmlEPTB;ND64O|cyOyEQvF2= MVXTRW5ITVJ?
HCC1569 MnrpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWTrWJZkUUN3ME20Mlg5PDV6IN88US=> M4Dtb3NCVkeHUh?=
TE-6 M1fNUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MULJR|UxRTRwOUO5O|ch|ryP MVzTRW5ITVJ?
SK-N-FI NEHITGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1jqV2lEPTB;ND65OFQzOSEQvF2= MkHJV2FPT0WU
PANC-03-27 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGXhclBKSzVyPUSuPVk6PjJizszN MXjTRW5ITVJ?
MCF7 M1LkbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHPyWIRKSzVyPUWuNFA4OzhizszN MWHTRW5ITVJ?
UACC-257 M3TZfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1XkVGlEPTB;NT6wNlg1PSEQvF2= M2G1T3NCVkeHUh?=
SW1088 M17RWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVXJR|UxRTVwMEK5OFQh|ryP NFj5TlFUSU6JRWK=
A704 NXnu[2VpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4Dm[2lEPTB;NT6wN|A3KM7:TR?= MkP6V2FPT0WU
A2058 Mk\JS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnLwTWM2OD13LkC1PVA5KM7:TR?= M3vVOXNCVkeHUh?=
Calu-3 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWHTRpJFUUN3ME21MlA3PDV{IN88US=> MmCzV2FPT0WU
RERF-LC-MS M1XsdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoPGTWM2OD13LkC2PVA{KM7:TR?= NVjXTYVrW0GQR1XS
AU565 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn3UTWM2OD13LkC5O|AzKM7:TR?= NIflSFhUSU6JRWK=
DMS-79 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1;PSGlEPTB;NT6xN|g5OyEQvF2= M4P3cHNCVkeHUh?=
DK-MG MoTKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4nDWWlEPTB;NT6xPFQ{QCEQvF2= Mor0V2FPT0WU
HuCCT1 MnnXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmPoTWM2OD13LkKzPFU3KM7:TR?= NGrXVXhUSU6JRWK=
HT-144 MlzaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NU\1TZhpUUN3ME21MlI1QTh5IN88US=> MVPTRW5ITVJ?
M059J NHfSU3JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTVwMkW3OkDPxE1? MX3TRW5ITVJ?
COLO-792 M4K1bWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEPsTXhKSzVyPUWuNlY{PTZizszN MWjTRW5ITVJ?
SF539 NGLGO2lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWrJR|UxRTVwMk[2N|Ih|ryP NH3JRZNUSU6JRWK=
SK-UT-1 NH\zc5RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoLFTWM2OD13LkK3O|UyKM7:TR?= NGDPU49USU6JRWK=
NCI-H1703 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{Dzc2lEPTB;NT6zOVgzPiEQvF2= NYLUTlJTW0GQR1XS
SW837 Ml7LS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2P1[2lEPTB;NT6zO|g4QCEQvF2= MWTTRW5ITVJ?
U251 NI\GU5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXjTb4I5UUN3ME21MlM6ODl4IN88US=> M{PWOXNCVkeHUh?=
SW1710 M2\lOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{jMTWlEPTB;NT60NVU2PCEQvF2= NXz0bVRWW0GQR1XS
NCI-H1299 NX31ZXM4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWrJR|UxRTVwNE[zN|Uh|ryP NWnMRpM4W0GQR1XS
RVH-421 NGTjU2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVjYNJU{UUN3ME21MlQ6QTB6IN88US=> NHv2[2NUSU6JRWK=
UM-UC-3 MlrDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWjJR|UxRTVwNkK2OVEh|ryP NHjQXphUSU6JRWK=
MDA-MB-175-VII NXjlW4psT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NU\1WXRXUUN3ME21MlY1ODRzIN88US=> MmPWV2FPT0WU
KYSE-270 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3zsVWlEPTB;NT62OlA{OSEQvF2= M{XlXHNCVkeHUh?=
COLO-668 M1jNc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnLaTWM2OD13LkexN|Ih|ryP MkLMV2FPT0WU
LN-405 MmTwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIXofGFKSzVyPUWuO|MxQDVizszN MVPTRW5ITVJ?
HT-1376 NWfzWlZoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVLJR|UxRTVwN{iwOVIh|ryP NGDxbJhUSU6JRWK=
769-P NH62cmZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH62cHFKSzVyPUWuPFY4OThizszN NGfMTndUSU6JRWK=
HuP-T3 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHrYZldKSzVyPUWuPFg3PzdizszN NIHpS4hUSU6JRWK=
MDA-MB-415 M2nZUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXLRPWI{UUN3ME21MlkzOTN7IN88US=> NXXZVoZ{W0GQR1XS
MKN7 NIXrWJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmHjTWM2OD13Lkm4PEDPxE1? NH22R|FUSU6JRWK=
KS-1 M4rFU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEPZXFZKSzVyPUWuPVg5OzZizszN NWTG[JJxW0GQR1XS
647-V MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4DOWWlEPTB;NT65PVE1QCEQvF2= MWrTRW5ITVJ?
COLO-679 NF:5N2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{Pp[WlEPTB;Nj6wNFI2PSEQvF2= MYDTRW5ITVJ?
AN3-CA NXzGV|M{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXzJR|UxRTZwMEO0OFEh|ryP Mkj1V2FPT0WU
C32 MnTQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV7IUXhlUUN3ME22MlE{ODN2IN88US=> M2jEenNCVkeHUh?=
KM12 MoPIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVHKZ|J{UUN3ME22MlI1ODl7IN88US=> MVvTRW5ITVJ?
KINGS-1 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoHrTWM2OD14LkK2NVUzKM7:TR?= MUjTRW5ITVJ?
KYSE-410 Ml\iS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWe2TndzUUN3ME22MlMxPjR3IN88US=> NWqzO3Y{W0GQR1XS
HPAF-II M{DHU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYXJR|UxRTZwM{W0PEDPxE1? M1rPUnNCVkeHUh?=
LAN-6 M3L1Z2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH\3bZJKSzVyPU[uOFk3OzFizszN NXjldXZKW0GQR1XS
LU-99A NEfsVYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWfJR|UxRTZwNUW5PFkh|ryP MWXTRW5ITVJ?
SJSA-1 NF[wTldIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIG1eWJKSzVyPU[uOVY{PDdizszN MVjTRW5ITVJ?
MSTO-211H NGWze2lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGjpRnZKSzVyPU[uO|IzOzNizszN Moe5V2FPT0WU
SW900 NHj6VY9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmfXTWM2OD14Lke2NlIyKM7:TR?= MYjTRW5ITVJ?
LNCaP-Clone-FGC NIfCN5hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV7JR|UxRTZwOEC0NFMh|ryP MlOxV2FPT0WU
OMC-1 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1LHVWlEPTB;Nj64OVQxOiEQvF2= NX64dItYW0GQR1XS
IST-MEL1 NVu4[3dMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkLNTWM2OD14Lki5OlY6KM7:TR?= NYrn[nRGW0GQR1XS
TE-9 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX;JR|UxRTZwOEm4OFch|ryP MUfTRW5ITVJ?
NCI-H2030 NGX4R|dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV;BRo84UUN3ME22MlkyOjJ4IN88US=> MkezV2FPT0WU
BFTC-909 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGrWXnJKSzVyPUeuNFA3PDFizszN M2ftSnNCVkeHUh?=
NCI-SNU-5 M2PvV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1LXO2lEPTB;Nz6wNlE2QSEQvF2= MlrDV2FPT0WU
TE-5 M1zRS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmPQTWM2OD15LkCyPFgyKM7:TR?= NHrtdllUSU6JRWK=
SK-MES-1 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlPwTWM2OD15LkC1OFI4KM7:TR?= MVTTRW5ITVJ?
SHP-77 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{T0SWlEPTB;Nz6xN|k2OiEQvF2= NULsfVBOW0GQR1XS
NCI-H1623 M{TudGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4n6SGlEPTB;Nz6xOFA4OiEQvF2= MlrOV2FPT0WU
TE-11 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlTqTWM2OD15LkG1NVg1KM7:TR?= M170c3NCVkeHUh?=
EKVX NGDVe5NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWjaUmk6UUN3ME23MlE6OjZ5IN88US=> NG\YcYhUSU6JRWK=
OVCAR-3 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnzrTWM2OD15LkKxNVM{KM7:TR?= NIqwVIlUSU6JRWK=
C3A Mn7CS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoXBTWM2OD15LkO0OVIh|ryP NFnCUG9USU6JRWK=
CFPAC-1 NEDVe5ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWTJR|UxRTdwM{[yNlIh|ryP MYLTRW5ITVJ?
MG-63 MkTjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVrJR|UxRTdwNEG4OFkh|ryP MUfTRW5ITVJ?
KYSE-140 MkD0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXTETGFUUUN3ME23MlQ1ODZzIN88US=> M1jRV3NCVkeHUh?=
MPP-89 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlvvTWM2OD15LkW5O|I6KM7:TR?= MWfTRW5ITVJ?
COLO-824 MoP1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1\1bGlEPTB;Nz63Nlg3OyEQvF2= MX;TRW5ITVJ?
SiHa M4LrW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3zGdWlEPTB;Nz64N|cxPyEQvF2= MYnTRW5ITVJ?
SNU-387 NID3SpRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NU\mOnJ6UUN3ME23Mlg2OzR5IN88US=> MmXaV2FPT0WU
A172 M4XvO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1GyXWlEPTB;Nz64OlE4OiEQvF2= MYXTRW5ITVJ?
COLO-680N M4HkOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWq1T4dvUUN3ME23MlkyPzNizszN Ml7lV2FPT0WU
HCC1395 M3LKcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHzhWJRKSzVyPUiuNFU1PTJizszN MojYV2FPT0WU
NCI-H28 M3PhTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFTUdYtKSzVyPUiuNFU6PjNizszN M13PZXNCVkeHUh?=
LC-2-ad MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NILmTotKSzVyPUiuNlE6OzdizszN NF7JPW5USU6JRWK=
S-117 NXz5Vm5iT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2XK[2lEPTB;OD6yOVM2OyEQvF2= MU\TRW5ITVJ?
NCI-H1838 NEnhXJRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M321VWlEPTB;OD6yOVc5OSEQvF2= Mk\3V2FPT0WU
PANC-10-05 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWe3eGxOUUN3ME24MlM4ODR5IN88US=> MWrTRW5ITVJ?
KALS-1 M{nMPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWHJR|UxRThwNUC5Nlgh|ryP MXvTRW5ITVJ?
LS-1034 MlHCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mk\KTWM2OD16LkW3OFM4KM7:TR?= MXLTRW5ITVJ?
TGBC1TKB M3jBTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGLy[4ZKSzVyPUiuO|M2OzVizszN MUjTRW5ITVJ?
OE19 M4PIRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUXJR|UxRThwN{[yOlIh|ryP MVXTRW5ITVJ?
D-502MG MnrBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoXkTWM2OD16Lke2PVk1KM7:TR?= M3\sWXNCVkeHUh?=
JEG-3 Mmr5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnrkTWM2OD16Lke4OlE5KM7:TR?= NEjJSWZUSU6JRWK=
DBTRG-05MG NU\EWlllT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUjJR|UxRThwOEe1OlUh|ryP NGTNUYZUSU6JRWK=
ME-180 M1HCemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{P5[mlEPTB;OT6wOlczPSEQvF2= M{jQeXNCVkeHUh?=
NCI-H1573 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnfmTWM2OD17LkGwOVMzKM7:TR?= M2DNdHNCVkeHUh?=
HCC2998 NIHVdZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M13QfWlEPTB;OT6xN|Y5OSEQvF2= M3z0RXNCVkeHUh?=
ACHN NHXLS2NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYrJR|UxRTlwMkS5O|Uh|ryP M3TmenNCVkeHUh?=
D-392MG NWP5c4JnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlnpTWM2OD17LkK1O|E2KM7:TR?= NWTRT2RCW0GQR1XS
no-11 MnO5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX;JR|UxRTlwMk[wNlgh|ryP MlTvV2FPT0WU
KLE Ml7ZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV3JR|UxRTlwM{KyN|Ih|ryP Mlz2V2FPT0WU
Calu-6 M1jZe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlXNTWM2OD17LkO3OVI5KM7:TR?= NEDoSHlUSU6JRWK=
LB831-BLC MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mk\NTWM2OD17LkS1NVcyKM7:TR?= NVPUSFlSW0GQR1XS
SW684 M1;qU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NI\MSphKSzVyPUmuOFYyOTZizszN M3;hV3NCVkeHUh?=
SH-4 M2HldGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYXJR|UxRTlwNEmzOlQh|ryP NV\WSW93W0GQR1XS
IST-MES1 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M120NmlEPTB;OT61NVY1PCEQvF2= M1;TNnNCVkeHUh?=
Saos-2 NWrKbFROT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlTNTWM2OD17LkWyNVk2KM7:TR?= NH7qNmFUSU6JRWK=
NCI-H2087 NWrI[VhWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYLkR3R[UUN3ME25MlY4OzV{IN88US=> NFXZUXdUSU6JRWK=
SCC-9 M4H1bWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXXJR|UxRTlwN{G4NVYh|ryP NVnuTJhmW0GQR1XS
MFE-280 MmLaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1jsV2lEPTB;OT63Nlc5PSEQvF2= MoTyV2FPT0WU
BEN MoHVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWTsVmYzUUN3ME25MlgzOTV7IN88US=> Mo\GV2FPT0WU
CP50-MEL-B NHjD[HRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnvETWM2OD17LkmyOFMzKM7:TR?= MXnTRW5ITVJ?
SK-MEL-28 NH76NJdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXvHcWN2UUN3ME2xNE4xOTl|IN88US=> M{fLO3NCVkeHUh?=
NCI-H2452 NUn3ZlZGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUT3TYxwUUN3ME2xNE4yPiEQvF2= MUnTRW5ITVJ?
NCI-H1395 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGW5fldKSzVyPUGwMlE4QCEQvF2= MV;TRW5ITVJ?
NCI-H2052 NF7LZpJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NU\uO|RxUUN3ME2xNE4yQDh{IN88US=> M3fad3NCVkeHUh?=
A375 NVfW[G1YT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnyyTWM2OD1zMD6yOFUzKM7:TR?= NX7qSlc2W0GQR1XS
HCC38 NWfCeHlsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmflTWM2OD1zMD6zNlIh|ryP MWTTRW5ITVJ?
LK-2 MmXVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3;pZmlEPTB;MUCuOFIxQCEQvF2= MW\TRW5ITVJ?
SF126 MlSwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWrHc|BqUUN3ME2xNE41PzJ5IN88US=> NUPJbXBRW0GQR1XS
SK-MEL-1 NYLlflhvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4PLOGlEPTB;MUCuO|g{QCEQvF2= MV;TRW5ITVJ?
ACN M3zoTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3vSN2lEPTB;MUCuPFY4QSEQvF2= NI\rR4RUSU6JRWK=
BB30-HNC NFHRZmRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXvJR|UxRTFyLki3NVEh|ryP MWTTRW5ITVJ?
NCI-H747 M3zaWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MonpTWM2OD1zMD64O|Q3KM7:TR?= M4naWXNCVkeHUh?=
KYSE-150 MlPYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoXsTWM2OD1zMT6wN|g4KM7:TR?= M2[4SnNCVkeHUh?=
D-247MG NFXmWWRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2rBZWlEPTB;MUGuNVAxQSEQvF2= NWn0RpNiW0GQR1XS
BxPC-3 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEDsfpRKSzVyPUGxMlM4PDdizszN NUnKV2VUW0GQR1XS
SK-MEL-30 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVLHSpM1UUN3ME2xNU41ODd7IN88US=> MX7TRW5ITVJ?
CAS-1 NHXR[ZpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkD6TWM2OD1zMT60NVA6KM7:TR?= NYfYWoNZW0GQR1XS
no-10 NHnOWYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1jPb2lEPTB;MUKuNVIyPyEQvF2= NUDFS4E{W0GQR1XS
NCI-H2405 NG\pPWhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXXJR|UxRTF{LkKwN|Yh|ryP M3;zfnNCVkeHUh?=
KGN NGrvZ4dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn3vTWM2OD1zMj6yPVAyKM7:TR?= MWTTRW5ITVJ?
BB49-HNC MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlTrTWM2OD1zMj6zPVU3KM7:TR?= NIO1OXJUSU6JRWK=
NCI-H1693 NGLvdnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NED1RopKSzVyPUGyMlU5OTZizszN NXr2PY5sW0GQR1XS
RO82-W-1 NUT2TJY6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4ThRWlEPTB;MUOuNFY1QSEQvF2= NHjNSndUSU6JRWK=
CAL-85-1 M{fGSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIDvem5KSzVyPUGzMlQ{QTlizszN MX\TRW5ITVJ?
H-EMC-SS MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NU[wfWZwUUN3ME2xN{46OTB2IN88US=> NFrN[lhUSU6JRWK=
SW1783 NV3hdXFjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2TYd2lEPTB;MUSuNlM6OSEQvF2= MlywV2FPT0WU
LB771-HNC M{HvTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXj5W2tqUUN3ME2xOE41OTlizszN NYPaTHl[W0GQR1XS
HCC70 NUP2VlZPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVjQeotYUUN3ME2xOE41OjN|IN88US=> NVjDcIdEW0GQR1XS
KNS-81-FD MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlH4TWM2OD1zND63NFQ2KM7:TR?= NY\NepA1W0GQR1XS
KYSE-520 NHLJ[HpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn;ITWM2OD1zND65Nlch|ryP M3XJTHNCVkeHUh?=
TGBC24TKB NUH3emtNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV3W[YdOUUN3ME2xOE46PTN7IN88US=> MW\TRW5ITVJ?
SNB75 M{CyOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlG2TWM2OD1zNT6wO|I6KM7:TR?= M{\nO3NCVkeHUh?=
SW872 MoDPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIK2WVFKSzVyPUG1MlIzOThizszN MnLuV2FPT0WU
U031 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYLJR|UxRTF3LkiwNlgh|ryP NVzTfY82W0GQR1XS
ChaGo-K-1 MnG1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkTQTWM2OD1zNT64N|U6KM7:TR?= MUPTRW5ITVJ?
NCI-H441 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEjWR2JKSzVyPUG2MlAxOzlizszN NVz0WIFiW0GQR1XS
TE-12 MoX2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEHEc2RKSzVyPUG2MlE5PzNizszN MnHBV2FPT0WU
NCI-H1755 M3vtdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mnj2TWM2OD1zNj61O|Mh|ryP MoXuV2FPT0WU
KNS-42 NF;UT2JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXLJR|UxRTF4Lk[1PFkh|ryP NIfVRVRUSU6JRWK=
SK-PN-DW MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYrJR|UxRTF5LkSyNFEh|ryP M2jGT3NCVkeHUh?=
NCI-H226 M3XrRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnfKTWM2OD1zNz65N|Q2KM7:TR?= NW\WPYJIW0GQR1XS
K-562 M3;nZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NY\Ed49sUUN3ME2xPE43OzF5IN88US=> NHjqUJlUSU6JRWK=
A388 NHizb5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXu2e|F3UUN3ME2xPU4xOzB|IN88US=> NV76[pBrW0GQR1XS
ZR-75-30 NYHOSHpCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoHmTWM2OD1zOT6wPVY5KM7:TR?= NFHKd2hUSU6JRWK=
LU-135 NICxW5dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnvOTWM2OD1zOT6yOlM3KM7:TR?= M3P2XnNCVkeHUh?=
NCI-H2029 M1i1Omdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUnJR|UxRTF7Lk[wNlEh|ryP NGCzOpZUSU6JRWK=
HT-1197 NHnkXWlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NED1emFKSzVyPUG5MlkzOjdizszN NVr6Tnp{W0GQR1XS
IGR-1 NWXhbWhXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlP1TWM2OD1{MD6zNVE4KM7:TR?= NIn3NHZUSU6JRWK=
U-87-MG M{XjZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVrNOGtOUUN3ME2yNE43PDF|IN88US=> MWTTRW5ITVJ?
NCI-H1304 NWmyWnVmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MknNTWM2OD1{MD63OVAyKM7:TR?= NVHwXZBqW0GQR1XS
RCC10RGB M1nXXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH:4R5hKSzVyPUKxMlI5OjlizszN NYDVeJN[W0GQR1XS
NCI-H520 MnXhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXTJR|UxRTJ{Lke2NVEh|ryP MYnTRW5ITVJ?
SK-LU-1 NFvoUGxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFL2N4VKSzVyPUKzMlA4OThizszN MYrTRW5ITVJ?
UACC-893 MmDZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEnEcI5KSzVyPUKzMlExOzhizszN MYXTRW5ITVJ?
NCI-H2347 MkTaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUDJR|UxRTJ|LkK2O|Qh|ryP MnW2V2FPT0WU
U-118-MG Mnn0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEnzPI9KSzVyPUKzMlczOTdizszN MmL4V2FPT0WU
NCI-H596 NITaTGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlXETWM2OD1{Mz65NFU2KM7:TR?= NUTMO5dOW0GQR1XS
MZ1-PC NWHGWnJsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mmq4TWM2OD1{ND62O|U6KM7:TR?= NFO2dm9USU6JRWK=
SW1417 M3foc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV36VGN7UUN3ME2yOU4zPDl6IN88US=> NV\QcJltW0GQR1XS
NCI-H82 NGfoeWVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV;Xdmh2UUN3ME2yOk41Ojh6IN88US=> NXPBTY5oW0GQR1XS
COLO-678 M4PwXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NULQfXIyUUN3ME2yO{41QTF7IN88US=> NGnxVHpUSU6JRWK=
KURAMOCHI MojjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF;jSJNKSzVyPUK4MlEzPiEQvF2= NEn2dWlUSU6JRWK=
NCI-H1650 NFy0eHpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYHLS3pyUUN3ME2zNE4yQTJ2IN88US=> MWfTRW5ITVJ?
HCC1954 NWPiPIl6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4PLfGlEPTB;M{GuN|Y3PiEQvF2= NYXBdXhSW0GQR1XS
GAK NILjPY9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4XHeGlEPTB;M{KuNlYyPiEQvF2= MlHjV2FPT0WU
YAPC MnXDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmrCTWM2OD1|Mz63OlQ5KM7:TR?= M4f6fXNCVkeHUh?=
NCI-H2228 NVX6SWtST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWXJR|UxRTN2LkO2NFUh|ryP M{\E[XNCVkeHUh?=
VMRC-RCZ NWD6fmY5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NInQZ3RKSzVyPUO2MlMxOjJizszN MXrTRW5ITVJ?
NMC-G1 M{DjXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4nMdmlEPTB;M{euNFUzQSEQvF2= M3\LfnNCVkeHUh?=
D-336MG MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NW\6bGZoUUN3ME20NU45PDR{IN88US=> NFHJcpRUSU6JRWK=
UACC-62 NYGzTo1LT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmDwTWM2OD12Mj61OVA2KM7:TR?= NFn1bodUSU6JRWK=
C-33-A MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGjMdYxKSzVyPUS1MlMzPTZizszN NVfrc4ZwW0GQR1XS
HCC1937 NW\0U|NbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3:2RWlEPTB;NEeuNVk2QCEQvF2= NYjQbGtGW0GQR1XS
HDLM-2 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWDJR|UxRTR5LkKyPFch|ryP MnGzV2FPT0WU
NCI-H727 Mle2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnS2TWM2OD12Nz6yOFUyKM7:TR?= M121ZnNCVkeHUh?=
NY NYTmN5JVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWjvWJllUUN3ME20PU4{QTB6IN88US=> NXjPTGNYW0GQR1XS
NCI-H2291 NUnsbmpKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH7K[HdKSzVyPUS5Mlg{ODFizszN M4TVenNCVkeHUh?=

... Click to View More Cell Line Experimental Data
体内研究 Decitabine和Vorinostat都具有使肿瘤衰退的功能。然而, Decitabine 和 Vorinostat 联用使肿瘤衰退的效果更强。没有任何处理时,在野生型和Fasgld 小鼠中在肺肿瘤负担方面观察不到明显的区别。然而, Decitabine 和Vorinostat联用处理野生型小鼠，使肿瘤衰退比处理 Fasgld小鼠效果高很多。 Decitabine和Vorinostat使结肠癌细胞对FasL调节的肿瘤衰退敏感。低剂量Decitabine和Vorinostat处理，没有明显的肝脏毒性。[3]

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

激酶实验：[4]
+ 展开

组蛋白去乙酰化酶活性测定:

为了进行 HDAC 实验24 × 104 dpm 乙醇溶液(1 mCi/ml)中提供的sup>3H-醋酸钠盐标记的组蛋白H4等份样, 加到每个试管中，试管中含悬浮在25 µL实验buffer(100 mM Tris-HCl pH 8, 2mM EDTA)中的200 µg全部HeLa细胞裂解液进行免疫沉淀获得的HDAC。加入不同浓度Vorinostat，在30oC下温育90分钟。加入20 µL 终止缓冲液(0.5 N HCl, 0.08 M AcOH)终止反应。加入0.8 mL TBME提取释放放入氚醋酸盐。在8,000 × g 转速下离心5分钟，600 µL 有机相(上相) 转移到包含3 mL闪烁液的闪烁瓶中。
细胞实验：[4]
+ 展开
  • Cell lines: NB4, NCI-H460和HCT-116肿瘤细胞系
  • Concentrations: 0 μM - 0.1 μM
  • Incubation Time: 48小时
  • Method: NB4, NCI-H460和HCT-116肿瘤细胞系生长在200 µL 96孔板中，约10%汇合，生长24小时后，覆盖孔中。使用多种浓度 Vorinostat或溶剂处理肿瘤细胞24小时。处理后，冲洗实验板，移除Vorinostat，温育48小时。使用sulphorodamine B 实验测定Vorinostat处理后存活细胞的分数。
    (Only for Reference)
动物实验：[3]
+ 展开
  • Animal Models: 携带CT26 细胞的Fasgld BALB/cByJ小鼠
  • Formulation: Dissolved in DMSO
  • Dosages: 25 mg/kg
  • Administration: 静脉注射
    (Only for Reference)

溶解度 (25°C)

体外 DMSO 52 mg/mL (196.74 mM)
Ethanol 3 mg/mL (11.35 mM)
Water Insoluble
体内 从左到右依次将纯溶剂加入产品，现配现用(数据来自Selleck实验检测而非文献)：
2% DMSO+30% PEG 300+5% Tween 80+ddH2O 		5mg/mL

* 溶解度检测是由Selleck技术部门检测的，可能会和文献中提供的溶解度有所差异，这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 264.3
化学式

C14H20N2O3
CAS号 149647-78-9
稳定性 powder
in solvent
别名 SAHA, MK0683, suberoylanilide hydroxamic acid

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为:

质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时，请务必参考Selleck产品标签上、MSDS / COA（可在Selleck的产品页面获得）批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液，使用的计算公式为：

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时，请务必参考Selleck产品标签上、MSDS / COA（可在Selleck的产品页面获得）批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量：

总分子量：g/mol

注：化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

临床试验信息

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01281176 Active not recruiting Adult Solid Neoplasm National Cancer Institute (NCI) February 9 2011 Phase 1
NCT01189266 Active not recruiting Anaplastic Astrocytoma|Anaplastic Oligoastrocytoma|Brain Stem Glioma|Childhood Glioblastoma|Giant Cell Glioblastoma|Gliosarcoma|Untreated Childhood Anaplastic Astrocytoma|Untreated Childhood Anaplastic Oligoastrocytoma|Untreated Childhood Brain Stem Glioma|Untreated Childhood Giant Cell Glioblastoma|Untreated Childhood Gliosarcoma National Cancer Institute (NCI) August 9 2010 Phase 1|Phase 2
NCT00703664 Completed Recurrent Mantle Cell Lymphoma|Recurrent Non-Hodgkin Lymphoma National Cancer Institute (NCI) July 9 2008 Phase 2
NCT03198559 Suspended HIV Infections The Peter Doherty Institute for Infection and Immunity|Merck Sharp & Dohme Corp.|The Alfred|University of Melbourne August 8 2017 Phase 1|Phase 2
NCT02538510 Active not recruiting Head and Neck Squamous Cell Carcinoma|Recurrent Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Recurrent Nasopharynx Carcinoma|Recurrent Salivary Gland Carcinoma|Squamous Cell Carcinoma Metastatic in the Neck With Occult Primary|Stage III Major Salivary Gland Carcinoma|Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Stage III Nasopharyngeal Carcinoma|Stage IV Nasopharyngeal Carcinoma|Stage IVA Major Salivary Gland Carcinoma|Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Stage IVB Major Salivary Gland Carcinoma|Stage IVB Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Stage IVC Major Salivary Gland Carcinoma|Stage IVC Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma University of Washington|National Cancer Institute (NCI) October 8 2015 Phase 1|Phase 2
NCT01983969 Completed Advanced Cancers|Lymphoma M.D. Anderson Cancer Center November 7 2013 Phase 1|Phase 2

技术支持

在订购、运输、储存和使用我们的产品的任何阶段，您遇到的任何问题，均可以通过拨打我们的热线电话400-668-6834，或者技术支持邮箱tech@selleck.cn，直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题，请给我们留言。

  • * 必填项

常见问题及建议解决方法

  • 问题 1：

    What’s the recommendation about reconstitution of the compound for in vivo animal study?

  • 回答：

    We recommend the following vehicle for S1047: 2% DMSO, 40% PEG 300, 5% Propylene glycol, 1% Tween 80 at 5 mg/mL.

Selleck产品目录册

HDAC Signaling Pathway Map

HDAC Inhibitors with Unique Features

相关HDAC产品

  • LMK-235 New

    LMK-235是HDAC4和HDAC5的选择性抑制剂， IC50分别为11.9 nM 和 4.2 nM。

  • CAY10603 New

    CAY10603是一种强效的选择性HDAC6抑制剂，IC50为2 pM，选择性比其它HDACs高200多倍。

  • 4SC-202 New

    4SC-202是一种选择性的I类HDAC抑制剂，对HDAC1，HDAC2，和HDAC3的IC50分别为1.20 μM，1.12 μM，和0.57 μM。也对Lysine specific demethylase 1 (LSD1)表现出抑制活性。Phase 1。

  • Panobinostat (LBH589)

    Panobinostat (LBH589)是一种新型的，广谱HDAC抑制剂，无细胞试验中IC50为5 nM。Phase 3。

  • Entinostat (MS-275)

    Entinostat (MS-275)强烈抑制HDAC1和HDAC3，无细胞试验中IC50分别为0.51 μM和1.7 μM，抑制作用强于HDACs 4， 6， 8，和10。Phase 3。

  • Trichostatin A (TSA)

    Trichostatin A (TSA)是一种HDAC抑制剂，无细胞试验中IC50为1.8 nM左右。

  • Romidepsin (FK228, Depsipeptide)

    Romidepsin (FK228, Depsipeptide)是一种有效的HDAC1和HDAC2抑制剂，无细胞试验中IC50分别为36 nM和47 nM。

    Features:Romidepsin对I型HDAC的抑制作用明显强于对II型HDAC的抑制。

  • RGFP966

    RGFP966是一种HDAC3抑制剂，无细胞试验中IC50为0.08μM ，比作用于其他HDAC选择性高200倍以上。

  • Tubastatin A

    Tubastatin A是一种有效的，选择性HDAC6抑制剂，无细胞试验中IC50为15 nM，选择性远高于所有其他同工酶(1000倍)除了HDAC8(57倍)。

  • Mocetinostat (MGCD0103)

    Mocetinostat (MGCD0103)是一种有效的HDAC抑制剂，对HDAC1抑制作用最强，无细胞试验中IC50为0.15 μM，比作用于HDAC2， 3，和11选择性高2到10倍，对HDAC4， 5， 6， 7，和8没有抑制活性。Phase 2。

Tags: 购买Vorinostat (SAHA, MK0683) | Vorinostat (SAHA, MK0683)供应商 | 采购Vorinostat (SAHA, MK0683) | Vorinostat (SAHA, MK0683)价格 | Vorinostat (SAHA, MK0683)生产 | 订购Vorinostat (SAHA, MK0683) | Vorinostat (SAHA, MK0683)代理商
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID