Gemcitabine

别名: LY-188011, NSC 613327 中文名称:吉西他滨

此产品请避光密封保存。

Gemcitabine是核酸合成抑制剂,是有效、特异的脱氧胞苷类似物,用于化疗。Gemcitabine可诱导有效的p53依赖的凋亡。

Gemcitabine Chemical Structure

Gemcitabine Chemical Structure

CAS: 95058-81-4

规格 价格 库存 购买数量
10mM (1mL in DMSO) RMB 1057.63 现货
50mg RMB 782.86 现货
200mg RMB 1613.43 现货
1g RMB 4013.1 现货
更大包装 有超大折扣

400-668-6834

info@selleck.cn

免费分装
免费预溶

客户使用Selleck的Gemcitabine发表文献248

产品质控

批次: 纯度: 99.98%
99.98

Gemcitabine相关产品

DNA/RNA Synthesis抑制剂选择性比较

细胞实验数据示例

细胞系 实验类型 给药浓度 孵育时间 活性描述 文献信息
SW1573 Cytotoxicity assay 72 hrs Cytotoxicity against SW1573 cells after 72 hrs by SRB assay, IC50 = 8.3 μM. 17419604
A549 Cytotoxicity assay 72 hrs Cytotoxicity against A549 cells after 72 hrs by SRB assay, IC50 = 13.1 μM. 17419604
OVCAR8 Antiproliferative assay 72 hrs Antiproliferative activity against p53 deficient human OVCAR8 cells after 72 hrs by proliferative assay, IC50 = 0.0026 μM. 18469809
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 0.0026 μM. 18469809
A2780/E6 Antiproliferative assay 72 hrs Antiproliferative activity against p53 deficient human A2780/E6 cells after 72 hrs by proliferative assay, IC50 = 0.0026 μM. 18469809
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 0.0097 μM. 18469809
HCT15 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT15 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 0.0099 μM. 18469809
SF268 Antiproliferative assay 72 hrs Antiproliferative activity against p53 deficient human SF268 cells after 72 hrs, IC50 = 0.0103 μM. 18469809
SW480 Antiproliferative assay 72 hrs Antiproliferative activity against p53 deficient human SW480 cells after 72 hrs by proliferative assay, IC50 = 0.0136 μM. 18469809
A2780 Antiproliferative assay 72 hrs Antiproliferative activity against human A2780 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 0.0166 μM. 18469809
SF539 Antiproliferative assay 72 hrs Antiproliferative activity against human SF539 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 0.0198 μM. 18469809
Jurkat Antiproliferative assay 72 hrs Antiproliferative activity against p53 deficient human Jurkat cells after 72 hrs by proliferative assay, IC50 = 0.0453 μM. 18469809
COLO205 Antiproliferative assay 72 hrs Antiproliferative activity against p53 deficient human COLO205 cells after 72 hrs, IC50 = 0.0514 μM. 18469809
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 0.0803 μM. 18469809
U2OS Antiproliferative assay 72 hrs Antiproliferative activity against human U2OS cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 0.0907 μM. 18469809
K562 Antiproliferative assay 72 hrs Antiproliferative activity against p53 deficient human K562 cells after 72 hrs, IC50 = 0.7459 μM. 18469809
HCT116/E6 Antiproliferative assay 72 hrs Antiproliferative activity against p53 deficient human HCT116/E6 cells after 72 hrs by proliferative assay, IC50 = 0.8965 μM. 18469809
MCF7 Antitumor assay 48 hrs Antitumor activity against human MCF7 cells after 48 hrs by MTS assay, GI50 = 0.01 μM. 18588281
HT29 Antitumor assay 48 hrs Antitumor activity against human HT29 cells after 48 hrs by MTS assay, GI50 = 0.03 μM. 18588281
CaCo2 Antitumor assay 48 hrs Antitumor activity against human CaCo2 cells after 48 hrs by MTS assay, GI50 = 0.18 μM. 18588281
K562 Antitumor assay 48 hrs Antitumor activity against human K562 cells after 48 hrs by MTS assay, GI50 = 0.32 μM. 18588281
A2780 Cytotoxicity assay 72 hrs Cytotoxicity against human A2780 cells after 72 hrs by MTT assay, IC50 = 0.31 μM. 19362474
Bel7402 Cytotoxicity assay 72 hrs Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 0.84 μM. 19362474
SW1990 Cytotoxicity assay 72 hrs Cytotoxicity against human SW1990 cells after 72 hrs by MTT assay, IC50 = 1.2 μM. 19362474
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 1.4 μM. 19362474
Capan2 Cytotoxicity assay 72 hrs Cytotoxicity against human Capan2 cells after 72 hrs by MTT assay, IC50 = 1.7 μM. 19362474
HCT8 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT8 cells after 72 hrs by MTT assay, IC50 = 1.74 μM. 19362474
BxPC3 Cytotoxicity assay 72 hrs Cytotoxicity against human BxPC3 cells after 72 hrs by MTT assay, IC50 = 2.9 μM. 19362474
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 3.28 μM. 19362474
PANC1 Cytotoxicity assay 72 hrs Cytotoxicity against human PANC1 cells after 72 hrs by MTT assay, IC50 = 5.6 μM. 19362474
NCI-H23 Cytotoxicity assay 5 days Cytotoxicity against human NCI-H23 cells after 5 days by SRB assay, GI50 = 0.002 μM. 19929004
HCT15 Cytotoxicity assay 5 days Cytotoxicity against human HCT15 cells after 5 days by SRB assay, GI50 = 0.003 μM. 19929004
BT549 Cytotoxicity assay 5 days Cytotoxicity against human BT549 cells after 5 days by SRB assay, GI50 = 0.004 μM. 19929004
PC3 Cytotoxicity assay 5 days Cytotoxicity against human PC3 cells after 5 days by SRB assay, GI50 = 0.006 μM. 19929004
HB-1 Antiviral assay 24 hrs Antiviral activity against HCV 1a infected in human HB-1 cells assessed as inhibition of viral RNA replication after 24 hrs, EC50 = 1 μM. 20580554
OVCAR8 Antiproliferative assay 72 hrs Antiproliferative activity against human p53 deficient OVCAR8 cells after 72 hrs by celltiter-glo assay, IC50 = 0.003 μM. 20873740
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human p53 deficient PC3 cells after 72 hrs by celltiter-glo assay, IC50 = 0.003 μM. 20873740
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 0.006 μM. 20873740
SF268 Antiproliferative assay 72 hrs Antiproliferative activity against human p53 deficient SF268 cells after 72 hrs by celltiter-glo assay, IC50 = 0.01 μM. 20873740
HCT15 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT15 cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 0.01 μM. 20873740
SF539 Antiproliferative assay 72 hrs Antiproliferative activity against human SF539 cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 0.02 μM. 20873740
Jurkat Antiproliferative assay 72 hrs Antiproliferative activity against human p53 deficient Jurkat cells after 72 hrs by celltiter-glo assay, IC50 = 0.03 μM. 20873740
A2780 Antiproliferative assay 72 hrs Antiproliferative activity against human A2780 cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 0.035 μM. 20873740
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 0.08 μM. 20873740
U2OS Antiproliferative assay 72 hrs Antiproliferative activity against human U2OS cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 0.18 μM. 20873740
HCT116-E6 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116-E6 cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 0.5 μM. 20873740
K562 Antiproliferative assay 72 hrs Antiproliferative activity against human p53 deficient K562 cells after 72 hrs by celltiter-glo assay, IC50 = 0.6 μM. 20873740
SW480 Antiproliferative assay 72 hrs Antiproliferative activity against human p53 deficient SW480 cells after 72 hrs by celltiter-glo assay, IC50 = 1.7 μM. 20873740
COLO205 Antiproliferative assay 72 hrs Antiproliferative activity against human p53 deficient COLO205 cells after 72 hrs by celltiter-glo assay, IC50 = 3 μM. 20873740
BV173 Cytotoxicity assay 3 days Cytotoxicity against human BV173 cells after 3 days by MTT assay, IC50 = 0.001 μM. 21711054
MES-SA Cytotoxicity assay 3 days Cytotoxicity against human MES-SA cells after 3 days by MTT assay, IC50 = 0.005 μM. 21711054
K562 Cytotoxicity assay 3 days Cytotoxicity against human paclitaxel resistant K562 cells after 3 days by MTT assay, IC50 = 0.006 μM. 21711054
CT26 Cytotoxicity assay 3 days Cytotoxicity against mouse CT26 cells after 3 days by MTT assay, IC50 = 0.006 μM. 21711054
EL4 Cytotoxicity assay 3 days Cytotoxicity against mouse EL4 cells after 3 days by MTT assay, IC50 = 0.007 μM. 21711054
L1210 Cytotoxicity assay 3 days Cytotoxicity against mouse L1210 cells after 3 days by MTT assay, IC50 = 0.007 μM. 21711054
BT549 Cytotoxicity assay 3 days Cytotoxicity against human BT549 cells after 3 days by MTT assay, IC50 = 0.008 μM. 21711054
P388D1 Cytotoxicity assay 3 days Cytotoxicity against mouse P388D1 cells after 3 days by MTT assay, IC50 = 0.019 μM. 21711054
CEM-DNR-bulk Cytotoxicity assay 3 days Cytotoxicity against human CEM-DNR-bulk cells after 3 days by MTT assay, IC50 = 0.022 μM. 21711054
HPAC Cytotoxicity assay 3 days Cytotoxicity against human HPAC cells after 3 days by MTT assay, IC50 = 0.073 μM. 21711054
MCF7 Cytotoxicity assay 3 days Cytotoxicity against human MCF7 cells after 3 days by MTT assay, IC50 = 0.149 μM. 21711054
MDA-MB-231 Cytotoxicity assay 3 days Cytotoxicity against human MDA-MB-231 cells after 3 days by MTT assay, IC50 = 0.245 μM. 21711054
C6 Cytotoxicity assay 3 days Cytotoxicity against rat C6 cells after 3 days by MTT assay, IC50 = 0.504 μM. 21711054
LNCAP Cytotoxicity assay 3 days Cytotoxicity against human LNCAP cells after 3 days by MTT assay, IC50 = 0.512 μM. 21711054
K562 Cytotoxicity assay 3 days Cytotoxicity against human K562 cells after 3 days by MTT assay, IC50 = 0.718 μM. 21711054
SK-N-AS Cytotoxicity assay 3 days Cytotoxicity against human SK-N-AS cells after 3 days by MTT assay, IC50 = 1.1 μM. 21711054
U87MG Cytotoxicity assay 3 days Cytotoxicity against human U87MG cells after 3 days by MTT assay, IC50 = 1.49 μM. 21711054
HT-29 Cytotoxicity assay 3 days Cytotoxicity against human HT-29 cells after 3 days by MTT assay, IC50 = 1.53 μM. 21711054
NCI-H146 Cytotoxicity assay 3 days Cytotoxicity against human NCI-H146 cells after 3 days by MTT assay, IC50 = 2.78 μM. 21711054
HeLa Cytotoxicity assay 3 days Cytotoxicity against human HeLa cells after 3 days by MTT assay, IC50 = 4.12 μM. 21711054
SK-MEL-2 Cytotoxicity assay 3 days Cytotoxicity against human SK-MEL-2 cells after 3 days by MTT assay, IC50 = 7.11 μM. 21711054
BJ Cytotoxicity assay 3 days Cytotoxicity against human BJ cells after 3 days by MTT assay, IC50 = 9.88 μM. 21711054
PANC1 Cytotoxicity assay 48 hrs Cytotoxicity against human PANC1 cells after 48 hrs by WST-8 assay, IC50 = 0.11 μM. 22342146
NCI-H460 Cytotoxicity assay 48 hrs Cytotoxicity against human NCI-H460 cells after 48 hrs by WST-8 assay, IC50 = 0.23 μM. 22342146
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells after 48 hrs by WST-8 assay, IC50 = 0.32 μM. 22342146
ACHN Cytotoxicity assay 48 hrs Cytotoxicity against human ACHN cells after 48 hrs by WST-8 assay, IC50 = 0.48 μM. 22342146
Calu1 Cytotoxicity assay 48 hrs Cytotoxicity against human Calu1 cells after 48 hrs by WST-8 assay, IC50 = 0.52 μM. 22342146
BxPC3 Growth inhibition assay 48 hrs Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay, GI50 = 3.64 μM. 22512908
BxPC3 Growth inhibition assay 48 hrs Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay, LC50 = 8.71 μM. 22512908
BxPC3 Growth inhibition assay 48 hrs Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay, TGI = 9.05 μM. 22512908
MIAPaCa2 Growth inhibition assay 48 hrs Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay, GI50 = 35.83 μM. 22512908
DMS53 Antiproliferative assay 72 hrs Antiproliferative activity at human DMS53 cells after 72 hrs by MTT assay, IC50 = 0.009 μM. 22861499
A549 Antiproliferative assay 72 hrs Antiproliferative activity at human A549 cells after 72 hrs by MTT assay, IC50 = 0.02 μM. 22861499
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by resazurin assay, IC50 = 0.05 μM. 22944119
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by resazurin assay, IC50 = 0.06 μM. 22944119
MIAPaCa2 Cytotoxicity assay 72 hrs Cytotoxicity against human MIAPaCa2 cells after 72 hrs by resazurin assay, IC50 = 0.06 μM. 22944119
BxPC3 Growth inhibition assay 48 hrs Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay, GI50 = 0.00364 μM. 23094992
BxPC3 Growth inhibition assay 48 hrs Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay, LC50 = 0.00871 μM. 23094992
BxPC3 Growth inhibition assay 48 hrs Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay, TGI = 0.00905 μM. 23094992
MIAPaCa2 Growth inhibition assay 48 hrs Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay, GI50 = 0.03583 μM. 23094992
MIAPaCa2 Growth inhibition assay 48 hrs Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay, TGI = 0.1 μM. 23094992
MIAPaCa2 Growth inhibition assay 48 hrs Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay, LC50 = 0.1 μM. 23094992
BL21(DE3) Function assay 1 min Drug metabolism assessed as 2',2'-difluorodeoxycytidine formation incubated for 1 min in presence of human recombinant N-terminal His-tagged DCK Pro122Ser mutant expressed in Escherichia coli BL21(DE3) cells by liquid chromatography-tandem mass spectromet, Km = 1.43 μM. 23230131
BL21(DE3) Function assay 1 min Drug metabolism assessed as 2',2'-difluorodeoxycytidine formation incubated for 1 min in presence of human recombinant N-terminal His-tagged DCK Ile24Val mutant expressed in Escherichia coli BL21(DE3) cells by liquid chromatography-tandem mass spectrometr, Km = 1.52 μM. 23230131
BL21(DE3) Function assay 1 min Drug metabolism assessed as 2',2'-difluorodeoxycytidine formation incubated for 1 min in presence of human recombinant N-terminal His-tagged DCK Ala119Gly mutant expressed in Escherichia coli BL21(DE3) cells by liquid chromatography-tandem mass spectromet, Km = 1.75 μM. 23230131
BL21(DE3) Function assay 1 min Activity of human recombinant N-terminal His-tagged wild type DCK expressed in Escherichia coli BL21(DE3) cells assessed as enzyme-mediated 2',2'-difluorodeoxycytidine formation incubated for 1 min by liquid chromatography-tandem mass spectrometry, Km = 2.15 μM. 23230131
MiaPaCa Cytotoxicity assay 6 days Cytotoxicity against human MiaPaCa cells assessed as inhibition of cell viability after 6 days by MTT assay, IC50 = 3 μM. 23360104
MiaPaCa Cytotoxicity assay 72 hrs Cytotoxicity against human MiaPaCa cells after 72 hrs by MTT assay, IC50 = 17.1 μM. 23489626
CV1 Cytotoxicity assay 72 hrs Cytotoxicity against african green monkey CV1 cells after 72 hrs by MTT assay, IC50 = 21.9 μM. 23489626
HT-29 Cytotoxicity assay 48 hrs Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 1.95 μM. 23968824
COLO205 Cytotoxicity assay 48 hrs Cytotoxicity against human COLO205 cells after 48 hrs by MTT assay, IC50 = 3.24 μM. 23968824
COLO320DM Cytotoxicity assay 48 hrs Cytotoxicity against human COLO320DM cells after 48 hrs by MTT assay, IC50 = 3.92 μM. 23968824
U373-MAGI Antiviral assay 2 hrs Antiviral activity against HIV1 infected in human U373-MAGI cells incubated for 2 hrs prior to viral infection followed by compound washout after 24 hrs measured 72 hrs post-infection by flow cytometry, EC50 = 0.0275 μM. 24120088
MCF7 Cytotoxicity assay 2 days Cytostatic activity against human MCF7 cells after 2 days by coulter counter analysis, IC50 = 0.0072 μM. 24341356
HeLa Cytotoxicity assay 4 days Cytostatic activity against human HeLa cells after 4 days by coulter counter analysis, IC50 = 0.0099 μM. 24341356
L1210 Cytotoxicity assay 2 days Cytostatic activity against mouse L1210 cells after 2 days by coulter counter analysis, IC50 = 0.013 μM. 24341356
CEM Cytotoxicity assay 3 days Cytostatic activity against human CEM cells after 3 days by coulter counter analysis, IC50 = 0.069 μM. 24341356
CEM Cytotoxicity assay 3 days Cytostatic activity against human dCK-deficient CEM cells after 3 days by coulter counter analysis, IC50 = 7.6 μM. 24341356
FTC-133 Cytotoxicity assay 24 hrs Cytotoxicity against human FTC-133 cells after 24 hrs by MTT assay, IC50 = 3.36 μM. 24436994
8305C Cytotoxicity assay 24 hrs Cytotoxicity against human 8305C cells after 24 hrs by MTT assay, IC50 = 4.53 μM. 24436994
L1210 Cytotoxicity assay 48 hrs Cytostatic activity against mouse L1210 cells after 48 hrs by coulter counter analysis, IC50 = 0.013 μM. 24471998
CEM Cytotoxicity assay 72 hrs Cytostatic activity against human CEM cells after 72 hrs by coulter counter analysis, IC50 = 0.086 μM. 24471998
BxPC3 Cytotoxicity assay 72 hrs Cytostatic activity against human BxPC3 cells after 72 hrs by MTS assay, IC50 = 0.67 μM. 24471998
MIAPaCa2 Cytotoxicity assay 72 hrs Cytostatic activity against human MIAPaCa2 cells after 72 hrs by MTS assay, IC50 = 1.04 μM. 24471998
K562 Cytotoxicity assay 48 hrs Cytotoxicity against human K562 cells assessed as reduction of cell survival after 48 hrs by MTT assay, IC50 = 0.05 μM. 24631359
CFPAC-1 Cytotoxicity assay 96 hrs Cytotoxicity against human CFPAC-1 cells assessed as reduction of cell survival after 96 hrs by MTT assay, IC50 = 0.35 μM. 24631359
CFPAC-1 Cytotoxicity assay 72 hrs Cytotoxicity against human CFPAC-1 cells assessed as reduction of cell survival after 72 hrs by MTT assay, IC50 = 0.47 μM. 24631359
HeLa Cytotoxicity assay 96 hrs Cytotoxicity against human HeLa cells assessed as reduction of cell survival after 96 hrs by MTT assay, IC50 = 0.9 μM. 24631359
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells assessed as reduction of cell survival after 72 hrs by MTT assay, IC50 = 10 μM. 24631359
MCF7 Cytotoxicity assay 24 hrs Cytotoxicity against human MCF7 cells assessed as cell viability after 24 hrs by WST-1 assay, LD50 = 0.004 μM. 24786915
HCT116 Cytotoxicity assay 24 hrs Cytotoxicity against human HCT116 cells assessed as cell viability after 24 hrs by WST-1 assay, LD50 = 0.005 μM. 24786915
RAW264.7 Cytotoxicity assay 24 hrs Cytotoxicity against mouse RAW264.7 cells assessed as cell viability after 24 hrs by WST-1 assay, LD50 = 0.005 μM. 24786915
MOLT4 Cytotoxicity assay 24 hrs Cytotoxicity against human MOLT4 cells assessed as cell viability after 24 hrs by WST-1 assay, LD50 = 0.008 μM. 24786915
Jurkat Cytotoxicity assay 24 hrs Cytotoxicity against human Jurkat cells assessed as cell viability after 24 hrs by WST-1 assay, LD50 = 0.012 μM. 24786915
HeLa Cytotoxicity assay 24 hrs Cytotoxicity against human HeLa cells assessed as cell viability after 24 hrs by WST-1 assay, LD50 = 0.023 μM. 24786915
BxPC3 Cytotoxicity assay 5 days Cytotoxicity against human BxPC3 cells after 5 days by PrestoBlue assay, EC50 = 0.01 μM. 24867590
MIAPaCa2 Cytotoxicity assay 5 days Cytotoxicity against human MIAPaCa2 cells after 5 days by PrestoBlue assay, EC50 = 2 μM. 24867590
MDA-MB-231 Antiproliferative assay 48 hrs Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 0.025 μM. 25350923
MDA-MB-231 Cytotoxicity assay 24 hrs Cytotoxicity against human MDA-MB-231 cells after 24 hrs by MTT colorimetric assay, IC50 = 0.19 μM. 25703296
MIAPaCa2 Cytotoxicity assay 24 hrs Cytotoxicity against human MIAPaCa2 cells after 24 hrs by MTT colorimetric assay, IC50 = 0.6 μM. 25703296
HeLa Cytotoxicity assay 24 hrs Cytotoxicity against human HeLa cells after 24 hrs by MTT colorimetric assay, IC50 = 3.3 μM. 25703296
A549 Cytotoxicity assay 24 hrs Cytotoxicity against human A549 cells treated at LA + compound sequent. compound for 24 hrs, LA + compound for 24 hrs additional, total 48 hrs 2:1 and 5:1 alpha-lipoic acid to compound ratio after 48 hrs by SRB assay in presence of alpha-lipoic acid, IC50 = 0.0039 μM. 25874330
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells treated at 2:1 and 5:1 alpha-lipoic acid to compound ratio after 48 hrs by SRB assay in presence of alpha-lipoic acid, IC50 = 0.0039 μM. 25874330
MRC5 Cytotoxicity assay 48 hrs Cytotoxicity against human MRC5 cells treated at 2:1 and 5:1 alpha-lipoic acid to compound ratio after 48 hrs by SRB assay in presence of alpha-lipoic acid, IC50 = 0.0039 μM. 25874330
T24 Cytotoxicity assay 48 hrs Cytotoxicity against human T24 cells treated at 2:1 and 5:1 alpha-lipoic acid to compound ratio after 48 hrs by SRB assay in presence of alpha-lipoic acid, IC50 = 0.0039 μM. 25874330
T24 Cytotoxicity assay 24 hrs Cytotoxicity against human T24 cells treated at LA + compound sequent. compound for 24 hrs, LA + compound for 24 hrs additional, total 48 hrs 2:1 and 5:1 alpha-lipoic acid to compound ratio after 48 hrs by SRB assay in presence of alpha-lipoic acid, IC50 = 0.0039 μM. 25874330
MRC5 Cytotoxicity assay 24 hrs Cytotoxicity against human MRC5 cells treated at LA + compound sequent. compound for 24 hrs, LA + compound for 24 hrs additional, total 48 hrs 2:1 and 5:1 alpha-lipoic acid to compound ratio after 48 hrs by SRB assay in presence of alpha-lipoic acid, IC50 = 0.0039 μM. 25874330
MRC5 Cytotoxicity assay 48 hrs Cytotoxicity against human MRC5 cells after 48 hrs by SRB assay, IC50 = 0.0063 μM. 25874330
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by SRB assay, IC50 = 0.0068 μM. 25874330
MRC5 Cytotoxicity assay 24 hrs Cytotoxicity against human MRC5 cells treated at LA + compound sequent. LA for 24 hrs), LA + GEM (24 hrs additional, total 48 hrs) 5:1 alpha-lipoic acid to compound ratio after 48 hrs by SRB assay in presence of alpha-lipoic acid, IC50 = 0.0068 μM. 25874330
T24 Cytotoxicity assay 48 hrs Cytotoxicity against human T24 cells after 48 hrs by SRB assay, IC50 = 0.0069 μM. 25874330
T24 Cytotoxicity assay 24 hrs Cytotoxicity against human T24 cells treated at LA + compound sequent. LA for 24 hrs), LA + GEM (24 hrs additional, total 48 hrs) 5:1 alpha-lipoic acid to compound ratio after 48 hrs by SRB assay in presence of alpha-lipoic acid, IC50 = 0.017 μM. 25874330
T24 Cytotoxicity assay 24 hrs Cytotoxicity against human T24 cells treated at LA + compound sequent. LA for 24 hrs), LA + GEM (24 hrs additional, total 48 hrs) 2:1 alpha-lipoic acid to compound ratio after 48 hrs by SRB assay in presence of alpha-lipoic acid, IC50 = 0.018 μM. 25874330
MRC5 Cytotoxicity assay 24 hrs Cytotoxicity against human MRC5 cells treated at LA + compound sequent. LA for 24 hrs), LA + GEM (24 hrs additional, total 48 hrs) 2:1 alpha-lipoic acid to compound ratio after 48 hrs by SRB assay in presence of alpha-lipoic acid, IC50 = 0.0216 μM. 25874330
A549 Cytotoxicity assay 24 hrs Cytotoxicity against human A549 cells treated at LA + compound sequent. LA for 24 hrs), LA + GEM (24 hrs additional, total 48 hrs) 2:1 alpha-lipoic acid to compound ratio after 48 hrs by SRB assay in presence of alpha-lipoic acid, IC50 = 0.029 μM. 25874330
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 0.15 μM. 26025875
HT-29 Cytotoxicity assay 72 hrs Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay, IC50 = 0.52 μM. 26025875
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay, IC50 = 0.65 μM. 26025875
Ramos Cytotoxicity assay 72 hrs Cytotoxicity against human Ramos cells assessed as reduction in cell viability after 72 hrs by MTS assay, EC50 = 0.00003 μM. 27032331
Jurkat Cytotoxicity assay 72 hrs Cytotoxicity against human Jurkat cells assessed as reduction in cell viability after 72 hrs by MTS assay, EC50 = 0.023 μM. 27032331
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTS assay, EC50 = 0.065 μM. 27032331
B16-F10-Luc-G5 Antiproliferative assay 24 hrs Antiproliferative activity against mouse B16-F10-Luc-G5 cells assessed as cell growth inhibition measured after 24 hrs by luciferase gene assay, IC50 = 11 μM. 27349332
SW1990 Cytotoxicity assay 48 hrs Cytotoxicity against human SW1990 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 2.3 μM. 27966950
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells incubated for 72 hrs under normoxic condition by MTT assay, IC50 = 0.57 μM. 28075592
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells incubated for 72 hrs under hypoxic condition by MTT assay, IC50 = 8.9 μM. 28075592
CCRF-CEM Cytotoxicity assay 72 hrs Cytotoxicity against daunorubicin resistant human CCRF-CEM cells assessed as cell growth inhibition after 72 hrs by MTS assay, IC50 = 0.02 μM. 28221790
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 72 hrs by MTS assay, IC50 = 0.03 μM. 28221790
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells assessed as cell growth inhibition after 72 hrs by MTS assay, IC50 = 0.05 μM. 28221790
K562-TAX Cytotoxicity assay 72 hrs Cytotoxicity against human K562-TAX cells assessed as cell growth inhibition after 72 hrs by MTS assay, IC50 = 0.05 μM. 28221790
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells assessed as cell growth inhibition after 72 hrs by MTS assay, IC50 = 0.1 μM. 28221790
CEM-DNR-bulk Cytotoxicity assay 72 hrs Cytotoxicity against mrp-1/mdr-1 overexpressing human CEM-DNR-bulk cells assessed as cell growth inhibition after 72 hrs by MTS assay, IC50 = 0.1 μM. 28221790
U2OS Cytotoxicity assay 72 hrs Cytotoxicity against human U2OS cells assessed as cell growth inhibition after 72 hrs by MTS assay, IC50 = 0.18 μM. 28221790
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against p53 deficient human HCT116 cells assessed as cell growth inhibition after 72 hrs by MTS assay, IC50 = 0.41 μM. 28221790
PANC1 Growth inhibition assay 72 hrs Growth inhibition of human PANC1 cells after 72 hrs by WST8 assay, GI50 = 5.8 μM. 28495081
BxPC3 Antiproliferative assay 72 hrs Antiproliferative activity against human BxPC3 cells after 72 hrs by CCK8 assay, IC50 = 20.2 μM. 28576633
AsPC1 Antiproliferative assay 72 hrs Antiproliferative activity against human AsPC1 cells after 72 hrs by CCK8 assay, IC50 = 26.8 μM. 28576633
PANC1 Antiproliferative assay 72 hrs Antiproliferative activity against human PANC1 cells after 72 hrs by CCK8 assay, IC50 = 30.4 μM. 28576633
MDA-MB-231 Growth inhibition assay 72 hrs Growth inhibition of human MDA-MB-231 cells after 72 hrs by Hoechst 33258 dye based fluorescence assay, IC50 = 0.03 μM. 29253340
HCT116 Growth inhibition assay 72 hrs Growth inhibition of human HCT116 cells after 72 hrs by Hoechst 33258 dye based fluorescence assay, IC50 = 0.03 μM. 29253340
MIAPaCa2 Cytotoxicity assay 72 hrs Cytotoxicity against human MIAPaCa2 cells assessed as decrease in cell proliferation after 72 hrs by MTT assay, IC50 = 0.11 μM. 29328656
MIAPaCa2 Cytotoxicity assay 72 hrs Cytotoxicity against gemcitabine-resistant human MIAPaCa2 cells assessed as decrease in cell proliferation after 72 hrs by MTT assay, IC50 = 3.3 μM. 29328656
BxPC3 Growth inhibition assay 96 hrs Growth inhibition of human BxPC3 cells after 96 hrs by SRB assay, IC50 = 0.006 μM. 29356532
Capan1 Growth inhibition assay 96 hrs Growth inhibition of human Capan1 cells after 96 hrs by SRB assay, IC50 = 0.019 μM. 29356532
MIAPaCa2 Antiproliferative assay 70 hrs Antiproliferative activity against human MIAPaCa2 cells after 70 hrs by alamar blue assay, IC50 = 0.12 μM. 29471119
PANC1 Cytotoxicity assay 72 hrs Cytotoxicity against human PANC1 cells after 72 hrs under normoxic condition by MTT assay, IC50 = 0.4 μM. 29656202
PANC1 Cytotoxicity assay 72 hrs Cytotoxicity against human PANC1 cells after 72 hrs under hypoxic condition by MTT assay, IC50 = 1.7 μM. 29656202
MDA-MB-231 Antiproliferative assay 48 hrs Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 0.0364 μM. 29795767
ES6 Growth inhibition assay Inhibition of human ES6 cell growth in a cell viability assay, IC50 = 0.0005856 μM. SANGER
SK-LMS-1 Growth inhibition assay Inhibition of human SK-LMS-1 cell growth in a cell viability assay, IC50 = 0.0005776 μM. SANGER
U031 Growth inhibition assay Inhibition of human U031 cell growth in a cell viability assay, IC50 = 0.0005647 μM. SANGER
SK-MEL-30 Growth inhibition assay Inhibition of human SK-MEL-30 cell growth in a cell viability assay, IC50 = 0.0005545 μM. SANGER
A3-KAW Growth inhibition assay Inhibition of human A3-KAW cell growth in a cell viability assay, IC50 = 0.0005512 μM. SANGER
Daoy Growth inhibition assay Inhibition of human Daoy cell growth in a cell viability assay, IC50 = 0.0004565 μM. SANGER
RS4-11 Growth inhibition assay Inhibition of human RS4-11 cell growth in a cell viability assay, IC50 = 0.0004326 μM. SANGER
YKG-1 Growth inhibition assay Inhibition of human YKG-1 cell growth in a cell viability assay, IC50 = 0.0004194 μM. SANGER
NCI-H1355 Growth inhibition assay Inhibition of human NCI-H1355 cell growth in a cell viability assay, IC50 = 0.0003806 μM. SANGER
SK-MES-1 Growth inhibition assay Inhibition of human SK-MES-1 cell growth in a cell viability assay, IC50 = 0.0003279 μM. SANGER
HC-1 Growth inhibition assay Inhibition of human HC-1 cell growth in a cell viability assay, IC50 = 0.0003273 μM. SANGER
TE-5 Growth inhibition assay Inhibition of human TE-5 cell growth in a cell viability assay, IC50 = 0.0003157 μM. SANGER
NCI-H2228 Growth inhibition assay Inhibition of human NCI-H2228 cell growth in a cell viability assay, IC50 = 0.000314 μM. SANGER
C-33-A Growth inhibition assay Inhibition of human C-33-A cell growth in a cell viability assay, IC50 = 0.0002733 μM. SANGER
A2780 Growth inhibition assay Inhibition of human A2780 cell growth in a cell viability assay, IC50 = 0.0002702 μM. SANGER
LB1047-RCC Growth inhibition assay Inhibition of human LB1047-RCC cell growth in a cell viability assay, IC50 = 0.0002688 μM. SANGER
LCLC-97TM1 Growth inhibition assay Inhibition of human LCLC-97TM1 cell growth in a cell viability assay, IC50 = 0.0002673 μM. SANGER
SK-PN-DW Growth inhibition assay Inhibition of human SK-PN-DW cell growth in a cell viability assay, IC50 = 0.0002656 μM. SANGER
647-V Growth inhibition assay Inhibition of human 647-V cell growth in a cell viability assay, IC50 = 0.0002481 μM. SANGER
ACN Growth inhibition assay Inhibition of human ACN cell growth in a cell viability assay, IC50 = 0.0002436 μM. SANGER
BB30-HNC Growth inhibition assay Inhibition of human BB30-HNC cell growth in a cell viability assay, IC50 = 0.0002312 μM. SANGER
SW982 Growth inhibition assay Inhibition of human SW982 cell growth in a cell viability assay, IC50 = 0.0002133 μM. SANGER
A431 Growth inhibition assay Inhibition of human A431 cell growth in a cell viability assay, IC50 = 0.0001831 μM. SANGER
NCI-H1299 Growth inhibition assay Inhibition of human NCI-H1299 cell growth in a cell viability assay, IC50 = 0.0001566 μM. SANGER
OCI-AML2 Growth inhibition assay Inhibition of human OCI-AML2 cell growth in a cell viability assay, IC50 = 0.0001466 μM. SANGER
IGROV-1 Growth inhibition assay Inhibition of human IGROV-1 cell growth in a cell viability assay, IC50 = 0.000145 μM. SANGER
MCF7 Growth inhibition assay Inhibition of human MCF7 cell growth in a cell viability assay, IC50 = 0.0001359 μM. SANGER
RT-112 Growth inhibition assay Inhibition of human RT-112 cell growth in a cell viability assay, IC50 = 0.0001273 μM. SANGER
769-P Growth inhibition assay Inhibition of human 769-P cell growth in a cell viability assay, IC50 = 0.0001231 μM. SANGER
AM-38 Growth inhibition assay Inhibition of human AM-38 cell growth in a cell viability assay, IC50 = 0.0001215 μM. SANGER
HSC-4 Growth inhibition assay Inhibition of human HSC-4 cell growth in a cell viability assay, IC50 = 0.0001022 μM. SANGER
NCI-H2122 Growth inhibition assay Inhibition of human NCI-H2122 cell growth in a cell viability assay, IC50 = 0.0000945 μM. SANGER
AGS Growth inhibition assay Inhibition of human AGS cell growth in a cell viability assay, IC50 = 0.0000902 μM. SANGER
DEL Growth inhibition assay Inhibition of human DEL cell growth in a cell viability assay, IC50 = 0.0000887 μM. SANGER
SW1710 Growth inhibition assay Inhibition of human SW1710 cell growth in a cell viability assay, IC50 = 0.0000751 μM. SANGER
IST-MEL1 Growth inhibition assay Inhibition of human IST-MEL1 cell growth in a cell viability assay, IC50 = 0.0000726 μM. SANGER
ARH-77 Growth inhibition assay Inhibition of human ARH-77 cell growth in a cell viability assay, IC50 = 0.0000711 μM. SANGER
LC-2-ad Growth inhibition assay Inhibition of human LC-2-ad cell growth in a cell viability assay, IC50 = 0.0000653 μM. SANGER
RPMI-6666 Growth inhibition assay Inhibition of human RPMI-6666 cell growth in a cell viability assay, IC50 = 0.0000652 μM. SANGER
NALM-6 Growth inhibition assay Inhibition of human NALM-6 cell growth in a cell viability assay, IC50 = 0.0000622 μM. SANGER
GR-ST Growth inhibition assay Inhibition of human GR-ST cell growth in a cell viability assay, IC50 = 0.0000595 μM. SANGER
CMK Growth inhibition assay Inhibition of human CMK cell growth in a cell viability assay, IC50 = 0.0000586 μM. SANGER
IST-SL2 Growth inhibition assay Inhibition of human IST-SL2 cell growth in a cell viability assay, IC50 = 0.0000584 μM. SANGER
RPMI-7951 Growth inhibition assay Inhibition of human RPMI-7951 cell growth in a cell viability assay, IC50 = 0.0000541 μM. SANGER
MHH-ES-1 Growth inhibition assay Inhibition of human MHH-ES-1 cell growth in a cell viability assay, IC50 = 0.0000531 μM. SANGER
HCE-4 Growth inhibition assay Inhibition of human HCE-4 cell growth in a cell viability assay, IC50 = 0.0000528 μM. SANGER
BB65-RCC Growth inhibition assay Inhibition of human BB65-RCC cell growth in a cell viability assay, IC50 = 0.0000512 μM. SANGER
HOS Growth inhibition assay Inhibition of human HOS cell growth in a cell viability assay, IC50 = 0.000048 μM. SANGER
TE-15 Growth inhibition assay Inhibition of human TE-15 cell growth in a cell viability assay, IC50 = 0.0000464 μM. SANGER
SNG-M Growth inhibition assay Inhibition of human SNG-M cell growth in a cell viability assay, IC50 = 0.0000425 μM. SANGER
HT-29 Growth inhibition assay Inhibition of human HT-29 cell growth in a cell viability assay, IC50 = 0.0000413 μM. SANGER
MEL-JUSO Growth inhibition assay Inhibition of human MEL-JUSO cell growth in a cell viability assay, IC50 = 0.0000391 μM. SANGER
SW1783 Growth inhibition assay Inhibition of human SW1783 cell growth in a cell viability assay, IC50 = 0.0000336 μM. SANGER
CHL-1 Growth inhibition assay Inhibition of human CHL-1 cell growth in a cell viability assay, IC50 = 0.0000324 μM. SANGER
LB2241-RCC Growth inhibition assay Inhibition of human LB2241-RCC cell growth in a cell viability assay, IC50 = 0.0000318 μM. SANGER
SK-UT-1 Growth inhibition assay Inhibition of human SK-UT-1 cell growth in a cell viability assay, IC50 = 0.0000297 μM. SANGER
ESS-1 Growth inhibition assay Inhibition of human ESS-1 cell growth in a cell viability assay, IC50 = 0.0000286 μM. SANGER
RKO Growth inhibition assay Inhibition of human RKO cell growth in a cell viability assay, IC50 = 0.0000278 μM. SANGER
ES1 Growth inhibition assay Inhibition of human ES1 cell growth in a cell viability assay, IC50 = 0.0000268 μM. SANGER
EW-16 Growth inhibition assay Inhibition of human EW-16 cell growth in a cell viability assay, IC50 = 0.000023 μM. SANGER
786-0 Growth inhibition assay Inhibition of human 786-0 cell growth in a cell viability assay, IC50 = 0.000023 μM. SANGER
HUTU-80 Growth inhibition assay Inhibition of human HUTU-80 cell growth in a cell viability assay, IC50 = 0.0000166 μM. SANGER
PSN1 Growth inhibition assay Inhibition of human PSN1 cell growth in a cell viability assay, IC50 = 0.0000165 μM. SANGER
NCI-SNU-1 Growth inhibition assay Inhibition of human NCI-SNU-1 cell growth in a cell viability assay, IC50 = 0.000016 μM. SANGER
EW-13 Growth inhibition assay Inhibition of human EW-13 cell growth in a cell viability assay, IC50 = 0.0000112 μM. SANGER
KGN Growth inhibition assay Inhibition of human KGN cell growth in a cell viability assay, IC50 = 0.0000108 μM. SANGER
SIG-M5 Growth inhibition assay Inhibition of human SIG-M5 cell growth in a cell viability assay, IC50 = 0.0000104 μM. SANGER
A375 Growth inhibition assay Inhibition of human A375 cell growth in a cell viability assay, IC50 = 0.0000099 μM. SANGER
QIMR-WIL Growth inhibition assay Inhibition of human QIMR-WIL cell growth in a cell viability assay, IC50 = 0.0000089 μM. SANGER
ALL-PO Growth inhibition assay Inhibition of human ALL-PO cell growth in a cell viability assay, IC50 = 0.0000083 μM. SANGER
RH-1 Growth inhibition assay Inhibition of human RH-1 cell growth in a cell viability assay, IC50 = 0.0000072 μM. SANGER
NKM-1 Growth inhibition assay Inhibition of human NKM-1 cell growth in a cell viability assay, IC50 = 0.0000071 μM. SANGER
SBC-5 Growth inhibition assay Inhibition of human SBC-5 cell growth in a cell viability assay, IC50 = 0.0000057 μM. SANGER
KE-37 Growth inhibition assay Inhibition of human KE-37 cell growth in a cell viability assay, IC50 = 0.0000056 μM. SANGER
BFTC-905 Growth inhibition assay Inhibition of human BFTC-905 cell growth in a cell viability assay, IC50 = 0.0000051 μM. SANGER
EW-7 Growth inhibition assay Inhibition of human EW-7 cell growth in a cell viability assay, IC50 = 0.0000026 μM. SANGER
KYSE-510 Growth inhibition assay Inhibition of human KYSE-510 cell growth in a cell viability assay, IC50 = 0.000001 μM. SANGER
ACHN Growth inhibition assay Inhibition of human ACHN cell growth in a cell viability assay, IC50 = 0.0000009 μM. SANGER
ES4 Growth inhibition assay Inhibition of human ES4 cell growth in a cell viability assay, IC50 = 0.0000007 μM. SANGER
MV-4-11 Growth inhibition assay Inhibition of human MV-4-11 cell growth in a cell viability assay, IC50 = 0.0000005 μM. SANGER
EoL-1-cell Growth inhibition assay Inhibition of human EoL-1-cell cell growth in a cell viability assay, IC50 = 0.0006162 μM. SANGER
NCI-H2009 Growth inhibition assay Inhibition of human NCI-H2009 cell growth in a cell viability assay, IC50 = 0.0006187 μM. SANGER
A4-Fuk Growth inhibition assay Inhibition of human A4-Fuk cell growth in a cell viability assay, IC50 = 0.0006263 μM. SANGER
KYSE-270 Growth inhibition assay Inhibition of human KYSE-270 cell growth in a cell viability assay, IC50 = 0.0006341 μM. SANGER
SK-LU-1 Growth inhibition assay Inhibition of human SK-LU-1 cell growth in a cell viability assay, IC50 = 0.0006552 μM. SANGER
SW872 Growth inhibition assay Inhibition of human SW872 cell growth in a cell viability assay, IC50 = 0.0007647 μM. SANGER
ES8 Growth inhibition assay Inhibition of human ES8 cell growth in a cell viability assay, IC50 = 0.0007802 μM. SANGER
G-402 Growth inhibition assay Inhibition of human G-402 cell growth in a cell viability assay, IC50 = 0.0007844 μM. SANGER
ATN-1 Growth inhibition assay Inhibition of human ATN-1 cell growth in a cell viability assay, IC50 = 0.0008069 μM. SANGER
DoTc2-4510 Growth inhibition assay Inhibition of human DoTc2-4510 cell growth in a cell viability assay, IC50 = 0.0009012 μM. SANGER
MES-SA Growth inhibition assay Inhibition of human MES-SA cell growth in a cell viability assay, IC50 = 0.0009049 μM. SANGER
SF268 Growth inhibition assay Inhibition of human SF268 cell growth in a cell viability assay, IC50 = 0.0009274 μM. SANGER
SF539 Growth inhibition assay Inhibition of human SF539 cell growth in a cell viability assay, IC50 = 0.001023 μM. SANGER
NB69 Growth inhibition assay Inhibition of human NB69 cell growth in a cell viability assay, IC50 = 0.001046 μM. SANGER
8505C Growth inhibition assay Inhibition of human 8505C cell growth in a cell viability assay, IC50 = 0.001063 μM. SANGER
CAL-12T Growth inhibition assay Inhibition of human CAL-12T cell growth in a cell viability assay, IC50 = 0.001084 μM. SANGER
BHY Growth inhibition assay Inhibition of human BHY cell growth in a cell viability assay, IC50 = 0.001141 μM. SANGER
LB647-SCLC Growth inhibition assay Inhibition of human LB647-SCLC cell growth in a cell viability assay, IC50 = 0.00118 μM. SANGER
CAL-62 Growth inhibition assay Inhibition of human CAL-62 cell growth in a cell viability assay, IC50 = 0.001215 μM. SANGER
MEG-01 Growth inhibition assay Inhibition of human MEG-01 cell growth in a cell viability assay, IC50 = 0.001266 μM. SANGER
MG-63 Growth inhibition assay Inhibition of human MG-63 cell growth in a cell viability assay, IC50 = 0.001335 μM. SANGER
SW620 Growth inhibition assay Inhibition of human SW620 cell growth in a cell viability assay, IC50 = 0.001346 μM. SANGER
A388 Growth inhibition assay Inhibition of human A388 cell growth in a cell viability assay, IC50 = 0.001365 μM. SANGER
BCPAP Growth inhibition assay Inhibition of human BCPAP cell growth in a cell viability assay, IC50 = 0.001452 μM. SANGER
P30-OHK Growth inhibition assay Inhibition of human P30-OHK cell growth in a cell viability assay, IC50 = 0.001459 μM. SANGER
Ca9-22 Growth inhibition assay Inhibition of human Ca9-22 cell growth in a cell viability assay, IC50 = 0.001538 μM. SANGER
VMRC-RCZ Growth inhibition assay Inhibition of human VMRC-RCZ cell growth in a cell viability assay, IC50 = 0.001542 μM. SANGER
LOXIMVI Growth inhibition assay Inhibition of human LOXIMVI cell growth in a cell viability assay, IC50 = 0.001596 μM. SANGER
L-540 Growth inhibition assay Inhibition of human L-540 cell growth in a cell viability assay, IC50 = 0.001602 μM. SANGER
NTERA-S-cl-D1 Growth inhibition assay Inhibition of human NTERA-S-cl-D1 cell growth in a cell viability assay, IC50 = 0.001641 μM. SANGER
MFH-ino Growth inhibition assay Inhibition of human MFH-ino cell growth in a cell viability assay, IC50 = 0.001656 μM. SANGER
Calu-6 Growth inhibition assay Inhibition of human Calu-6 cell growth in a cell viability assay, IC50 = 0.001735 μM. SANGER
HEL Growth inhibition assay Inhibition of human HEL cell growth in a cell viability assay, IC50 = 0.001791 μM. SANGER
CAL-33 Growth inhibition assay Inhibition of human CAL-33 cell growth in a cell viability assay, IC50 = 0.001893 μM. SANGER
HSC-3 Growth inhibition assay Inhibition of human HSC-3 cell growth in a cell viability assay, IC50 = 0.001905 μM. SANGER
KU812 Growth inhibition assay Inhibition of human KU812 cell growth in a cell viability assay, IC50 = 0.001913 μM. SANGER
EB2 Growth inhibition assay Inhibition of human EB2 cell growth in a cell viability assay, IC50 = 0.002012 μM. SANGER
SR Growth inhibition assay Inhibition of human SR cell growth in a cell viability assay, IC50 = 0.002121 μM. SANGER
NCI-H2087 Growth inhibition assay Inhibition of human NCI-H2087 cell growth in a cell viability assay, IC50 = 0.002143 μM. SANGER
H4 Growth inhibition assay Inhibition of human H4 cell growth in a cell viability assay, IC50 = 0.002175 μM. SANGER
EW-1 Growth inhibition assay Inhibition of human EW-1 cell growth in a cell viability assay, IC50 = 0.002223 μM. SANGER
MC-IXC Growth inhibition assay Inhibition of human MC-IXC cell growth in a cell viability assay, IC50 = 0.002264 μM. SANGER
NCI-H727 Growth inhibition assay Inhibition of human NCI-H727 cell growth in a cell viability assay, IC50 = 0.002506 μM. SANGER
MRK-nu-1 Growth inhibition assay Inhibition of human MRK-nu-1 cell growth in a cell viability assay, IC50 = 0.002567 μM. SANGER
COLO-668 Growth inhibition assay Inhibition of human COLO-668 cell growth in a cell viability assay, IC50 = 0.00266 μM. SANGER
CGTH-W-1 Growth inhibition assay Inhibition of human CGTH-W-1 cell growth in a cell viability assay, IC50 = 0.002723 μM. SANGER
CHP-212 Growth inhibition assay Inhibition of human CHP-212 cell growth in a cell viability assay, IC50 = 0.002752 μM. SANGER
GI-1 Growth inhibition assay Inhibition of human GI-1 cell growth in a cell viability assay, IC50 = 0.002764 μM. SANGER
HCC1806 Growth inhibition assay Inhibition of human HCC1806 cell growth in a cell viability assay, IC50 = 0.002908 μM. SANGER
HLE Growth inhibition assay Inhibition of human HLE cell growth in a cell viability assay, IC50 = 0.003004 μM. SANGER
HSC-2 Growth inhibition assay Inhibition of human HSC-2 cell growth in a cell viability assay, IC50 = 0.00303 μM. SANGER
DMS-273 Growth inhibition assay Inhibition of human DMS-273 cell growth in a cell viability assay, IC50 = 0.00307 μM. SANGER
DU-4475 Growth inhibition assay Inhibition of human DU-4475 cell growth in a cell viability assay, IC50 = 0.003143 μM. SANGER
LXF-289 Growth inhibition assay Inhibition of human LXF-289 cell growth in a cell viability assay, IC50 = 0.003314 μM. SANGER
PANC-03-27 Growth inhibition assay Inhibition of human PANC-03-27 cell growth in a cell viability assay, IC50 = 0.003513 μM. SANGER
GAMG Growth inhibition assay Inhibition of human GAMG cell growth in a cell viability assay, IC50 = 0.003739 μM. SANGER
NCI-H522 Growth inhibition assay Inhibition of human NCI-H522 cell growth in a cell viability assay, IC50 = 0.004337 μM. SANGER
SW626 Growth inhibition assay Inhibition of human SW626 cell growth in a cell viability assay, IC50 = 0.004464 μM. SANGER
HT-144 Growth inhibition assay Inhibition of human HT-144 cell growth in a cell viability assay, IC50 = 0.00492 μM. SANGER
MEL-HO Growth inhibition assay Inhibition of human MEL-HO cell growth in a cell viability assay, IC50 = 0.005162 μM. SANGER
BE-13 Growth inhibition assay Inhibition of human BE-13 cell growth in a cell viability assay, IC50 = 0.00521 μM. SANGER
VA-ES-BJ Growth inhibition assay Inhibition of human VA-ES-BJ cell growth in a cell viability assay, IC50 = 0.005256 μM. SANGER
NCI-H441 Growth inhibition assay Inhibition of human NCI-H441 cell growth in a cell viability assay, IC50 = 0.005597 μM. SANGER
KP-4 Growth inhibition assay Inhibition of human KP-4 cell growth in a cell viability assay, IC50 = 0.005611 μM. SANGER
LoVo Growth inhibition assay Inhibition of human LoVo cell growth in a cell viability assay, IC50 = 0.005714 μM. SANGER
HT-1080 Growth inhibition assay Inhibition of human HT-1080 cell growth in a cell viability assay, IC50 = 0.005834 μM. SANGER
GB-1 Growth inhibition assay Inhibition of human GB-1 cell growth in a cell viability assay, IC50 = 0.005845 μM. SANGER
IA-LM Growth inhibition assay Inhibition of human IA-LM cell growth in a cell viability assay, IC50 = 0.005906 μM. SANGER
8-MG-BA Growth inhibition assay Inhibition of human 8-MG-BA cell growth in a cell viability assay, IC50 = 0.00593 μM. SANGER
SK-HEP-1 Growth inhibition assay Inhibition of human SK-HEP-1 cell growth in a cell viability assay, IC50 = 0.006136 μM. SANGER
697 Growth inhibition assay Inhibition of human 697 cell growth in a cell viability assay, IC50 = 0.006247 μM. SANGER
KYSE-450 Growth inhibition assay Inhibition of human KYSE-450 cell growth in a cell viability assay, IC50 = 0.006315 μM. SANGER
HCC2998 Growth inhibition assay Inhibition of human HCC2998 cell growth in a cell viability assay, IC50 = 0.006339 μM. SANGER
HD-MY-Z Growth inhibition assay Inhibition of human HD-MY-Z cell growth in a cell viability assay, IC50 = 0.006679 μM. SANGER
OS-RC-2 Growth inhibition assay Inhibition of human OS-RC-2 cell growth in a cell viability assay, IC50 = 0.006681 μM. SANGER
SF126 Growth inhibition assay Inhibition of human SF126 cell growth in a cell viability assay, IC50 = 0.007054 μM. SANGER
Ca-Ski Growth inhibition assay Inhibition of human Ca-Ski cell growth in a cell viability assay, IC50 = 0.007093 μM. SANGER
NCI-H358 Growth inhibition assay Inhibition of human NCI-H358 cell growth in a cell viability assay, IC50 = 0.00716 μM. SANGER
J82 Growth inhibition assay Inhibition of human J82 cell growth in a cell viability assay, IC50 = 0.00741 μM. SANGER
NCI-H2342 Growth inhibition assay Inhibition of human NCI-H2342 cell growth in a cell viability assay, IC50 = 0.007634 μM. SANGER
OVCAR-8 Growth inhibition assay Inhibition of human OVCAR-8 cell growth in a cell viability assay, IC50 = 0.007904 μM. SANGER
TE-8 Growth inhibition assay Inhibition of human TE-8 cell growth in a cell viability assay, IC50 = 0.008001 μM. SANGER
ETK-1 Growth inhibition assay Inhibition of human ETK-1 cell growth in a cell viability assay, IC50 = 0.008076 μM. SANGER
HAL-01 Growth inhibition assay Inhibition of human HAL-01 cell growth in a cell viability assay, IC50 = 0.008195 μM. SANGER
KYSE-150 Growth inhibition assay Inhibition of human KYSE-150 cell growth in a cell viability assay, IC50 = 0.008469 μM. SANGER
NCI-H810 Growth inhibition assay Inhibition of human NCI-H810 cell growth in a cell viability assay, IC50 = 0.008558 μM. SANGER
ONS-76 Growth inhibition assay Inhibition of human ONS-76 cell growth in a cell viability assay, IC50 = 0.008677 μM. SANGER
NMC-G1 Growth inhibition assay Inhibition of human NMC-G1 cell growth in a cell viability assay, IC50 = 0.008762 μM. SANGER
C3A Growth inhibition assay Inhibition of human C3A cell growth in a cell viability assay, IC50 = 0.008839 μM. SANGER
PA-1 Growth inhibition assay Inhibition of human PA-1 cell growth in a cell viability assay, IC50 = 0.008993 μM. SANGER
SH-4 Growth inhibition assay Inhibition of human SH-4 cell growth in a cell viability assay, IC50 = 0.009022 μM. SANGER
EFO-27 Growth inhibition assay Inhibition of human EFO-27 cell growth in a cell viability assay, IC50 = 0.009046 μM. SANGER
CAPAN-1 Growth inhibition assay Inhibition of human CAPAN-1 cell growth in a cell viability assay, IC50 = 0.009227 μM. SANGER
DU-145 Growth inhibition assay Inhibition of human DU-145 cell growth in a cell viability assay, IC50 = 0.00929 μM. SANGER
A101D Growth inhibition assay Inhibition of human A101D cell growth in a cell viability assay, IC50 = 0.009373 μM. SANGER
ST486 Growth inhibition assay Inhibition of human ST486 cell growth in a cell viability assay, IC50 = 0.009406 μM. SANGER
NCI-H1437 Growth inhibition assay Inhibition of human NCI-H1437 cell growth in a cell viability assay, IC50 = 0.009418 μM. SANGER
HGC-27 Growth inhibition assay Inhibition of human HGC-27 cell growth in a cell viability assay, IC50 = 0.009601 μM. SANGER
8305C Growth inhibition assay Inhibition of human 8305C cell growth in a cell viability assay, IC50 = 0.00964 μM. SANGER
OCUB-M Growth inhibition assay Inhibition of human OCUB-M cell growth in a cell viability assay, IC50 = 0.01003 μM. SANGER
COLO-679 Growth inhibition assay Inhibition of human COLO-679 cell growth in a cell viability assay, IC50 = 0.01007 μM. SANGER
Detroit562 Growth inhibition assay Inhibition of human Detroit562 cell growth in a cell viability assay, IC50 = 0.01042 μM. SANGER
A204 Growth inhibition assay Inhibition of human A204 cell growth in a cell viability assay, IC50 = 0.01116 μM. SANGER
NCI-H1734 Growth inhibition assay Inhibition of human NCI-H1734 cell growth in a cell viability assay, IC50 = 0.01129 μM. SANGER
MC-CAR Growth inhibition assay Inhibition of human MC-CAR cell growth in a cell viability assay, IC50 = 0.01158 μM. SANGER
NCI-H2170 Growth inhibition assay Inhibition of human NCI-H2170 cell growth in a cell viability assay, IC50 = 0.01197 μM. SANGER
NCI-SNU-5 Growth inhibition assay Inhibition of human NCI-SNU-5 cell growth in a cell viability assay, IC50 = 0.01213 μM. SANGER
HCE-T Growth inhibition assay Inhibition of human HCE-T cell growth in a cell viability assay, IC50 = 0.01242 μM. SANGER
KYSE-180 Growth inhibition assay Inhibition of human KYSE-180 cell growth in a cell viability assay, IC50 = 0.01281 μM. SANGER
C8166 Growth inhibition assay Inhibition of human C8166 cell growth in a cell viability assay, IC50 = 0.01308 μM. SANGER
NCI-H460 Growth inhibition assay Inhibition of human NCI-H460 cell growth in a cell viability assay, IC50 = 0.01354 μM. SANGER
SNU-449 Growth inhibition assay Inhibition of human SNU-449 cell growth in a cell viability assay, IC50 = 0.01377 μM. SANGER
MDA-MB-468 Growth inhibition assay Inhibition of human MDA-MB-468 cell growth in a cell viability assay, IC50 = 0.01412 μM. SANGER
COR-L23 Growth inhibition assay Inhibition of human COR-L23 cell growth in a cell viability assay, IC50 = 0.01413 μM. SANGER
CTV-1 Growth inhibition assay Inhibition of human CTV-1 cell growth in a cell viability assay, IC50 = 0.01414 μM. SANGER
BL-41 Growth inhibition assay Inhibition of human BL-41 cell growth in a cell viability assay, IC50 = 0.01437 μM. SANGER
IGR-1 Growth inhibition assay Inhibition of human IGR-1 cell growth in a cell viability assay, IC50 = 0.01442 μM. SANGER
TK10 Growth inhibition assay Inhibition of human TK10 cell growth in a cell viability assay, IC50 = 0.01449 μM. SANGER
REH Growth inhibition assay Inhibition of human REH cell growth in a cell viability assay, IC50 = 0.01451 μM. SANGER
LU-139 Growth inhibition assay Inhibition of human LU-139 cell growth in a cell viability assay, IC50 = 0.01459 μM. SANGER
KP-N-YS Growth inhibition assay Inhibition of human KP-N-YS cell growth in a cell viability assay, IC50 = 0.01497 μM. SANGER
PANC-10-05 Growth inhibition assay Inhibition of human PANC-10-05 cell growth in a cell viability assay, IC50 = 0.01538 μM. SANGER
HL-60 Growth inhibition assay Inhibition of human HL-60 cell growth in a cell viability assay, IC50 = 0.01569 μM. SANGER
T84 Growth inhibition assay Inhibition of human T84 cell growth in a cell viability assay, IC50 = 0.01596 μM. SANGER
RPMI-8226 Growth inhibition assay Inhibition of human RPMI-8226 cell growth in a cell viability assay, IC50 = 0.01602 μM. SANGER
UM-UC-3 Growth inhibition assay Inhibition of human UM-UC-3 cell growth in a cell viability assay, IC50 = 0.01616 μM. SANGER
TE-10 Growth inhibition assay Inhibition of human TE-10 cell growth in a cell viability assay, IC50 = 0.01621 μM. SANGER
CAL-148 Growth inhibition assay Inhibition of human CAL-148 cell growth in a cell viability assay, IC50 = 0.01723 μM. SANGER
BV-173 Growth inhibition assay Inhibition of human BV-173 cell growth in a cell viability assay, IC50 = 0.01727 μM. SANGER
Calu-3 Growth inhibition assay Inhibition of human Calu-3 cell growth in a cell viability assay, IC50 = 0.01729 μM. SANGER
RPMI-2650 Growth inhibition assay Inhibition of human RPMI-2650 cell growth in a cell viability assay, IC50 = 0.01759 μM. SANGER
MKN45 Growth inhibition assay Inhibition of human MKN45 cell growth in a cell viability assay, IC50 = 0.01773 μM. SANGER
NUGC-3 Growth inhibition assay Inhibition of human NUGC-3 cell growth in a cell viability assay, IC50 = 0.01834 μM. SANGER
NCI-H520 Growth inhibition assay Inhibition of human NCI-H520 cell growth in a cell viability assay, IC50 = 0.01877 μM. SANGER
CCRF-CEM Growth inhibition assay Inhibition of human CCRF-CEM cell growth in a cell viability assay, IC50 = 0.01885 μM. SANGER
NCI-H2405 Growth inhibition assay Inhibition of human NCI-H2405 cell growth in a cell viability assay, IC50 = 0.0191 μM. SANGER
ES7 Growth inhibition assay Inhibition of human ES7 cell growth in a cell viability assay, IC50 = 0.01976 μM. SANGER
BPH-1 Growth inhibition assay Inhibition of human BPH-1 cell growth in a cell viability assay, IC50 = 0.02028 μM. SANGER
SAS Growth inhibition assay Inhibition of human SAS cell growth in a cell viability assay, IC50 = 0.0205 μM. SANGER
HuCCT1 Growth inhibition assay Inhibition of human HuCCT1 cell growth in a cell viability assay, IC50 = 0.02058 μM. SANGER
LOUCY Growth inhibition assay Inhibition of human LOUCY cell growth in a cell viability assay, IC50 = 0.02066 μM. SANGER
NCI-H292 Growth inhibition assay Inhibition of human NCI-H292 cell growth in a cell viability assay, IC50 = 0.02079 μM. SANGER
G-361 Growth inhibition assay Inhibition of human G-361 cell growth in a cell viability assay, IC50 = 0.02107 μM. SANGER
M059J Growth inhibition assay Inhibition of human M059J cell growth in a cell viability assay, IC50 = 0.02108 μM. SANGER
NCI-H1651 Growth inhibition assay Inhibition of human NCI-H1651 cell growth in a cell viability assay, IC50 = 0.02111 μM. SANGER
KALS-1 Growth inhibition assay Inhibition of human KALS-1 cell growth in a cell viability assay, IC50 = 0.02139 μM. SANGER
DJM-1 Growth inhibition assay Inhibition of human DJM-1 cell growth in a cell viability assay, IC50 = 0.02159 μM. SANGER
AU565 Growth inhibition assay Inhibition of human AU565 cell growth in a cell viability assay, IC50 = 0.02183 μM. SANGER
HCC38 Growth inhibition assay Inhibition of human HCC38 cell growth in a cell viability assay, IC50 = 0.02195 μM. SANGER
U251 Growth inhibition assay Inhibition of human U251 cell growth in a cell viability assay, IC50 = 0.02227 μM. SANGER
ABC-1 Growth inhibition assay Inhibition of human ABC-1 cell growth in a cell viability assay, IC50 = 0.02265 μM. SANGER
SK-NEP-1 Growth inhibition assay Inhibition of human SK-NEP-1 cell growth in a cell viability assay, IC50 = 0.02293 μM. SANGER
CESS Growth inhibition assay Inhibition of human CESS cell growth in a cell viability assay, IC50 = 0.02319 μM. SANGER
MIA-PaCa-2 Growth inhibition assay Inhibition of human MIA-PaCa-2 cell growth in a cell viability assay, IC50 = 0.02336 μM. SANGER
SUP-T1 Growth inhibition assay Inhibition of human SUP-T1 cell growth in a cell viability assay, IC50 = 0.02347 μM. SANGER
L-428 Growth inhibition assay Inhibition of human L-428 cell growth in a cell viability assay, IC50 = 0.02362 μM. SANGER
SW954 Growth inhibition assay Inhibition of human SW954 cell growth in a cell viability assay, IC50 = 0.02368 μM. SANGER
HO-1-N-1 Growth inhibition assay Inhibition of human HO-1-N-1 cell growth in a cell viability assay, IC50 = 0.02377 μM. SANGER
CHP-126 Growth inhibition assay Inhibition of human CHP-126 cell growth in a cell viability assay, IC50 = 0.02414 μM. SANGER
HMV-II Growth inhibition assay Inhibition of human HMV-II cell growth in a cell viability assay, IC50 = 0.02434 μM. SANGER
NB10 Growth inhibition assay Inhibition of human NB10 cell growth in a cell viability assay, IC50 = 0.02437 μM. SANGER
A172 Growth inhibition assay Inhibition of human A172 cell growth in a cell viability assay, IC50 = 0.02471 μM. SANGER
MONO-MAC-6 Growth inhibition assay Inhibition of human MONO-MAC-6 cell growth in a cell viability assay, IC50 = 0.02484 μM. SANGER
NCI-H1650 Growth inhibition assay Inhibition of human NCI-H1650 cell growth in a cell viability assay, IC50 = 0.0254 μM. SANGER
NH-12 Growth inhibition assay Inhibition of human NH-12 cell growth in a cell viability assay, IC50 = 0.0255 μM. SANGER
ML-2 Growth inhibition assay Inhibition of human ML-2 cell growth in a cell viability assay, IC50 = 0.02574 μM. SANGER
MZ2-MEL Growth inhibition assay Inhibition of human MZ2-MEL cell growth in a cell viability assay, IC50 = 0.02622 μM. SANGER
COLO-684 Growth inhibition assay Inhibition of human COLO-684 cell growth in a cell viability assay, IC50 = 0.02641 μM. SANGER
HuP-T4 Growth inhibition assay Inhibition of human HuP-T4 cell growth in a cell viability assay, IC50 = 0.0273 μM. SANGER
SW837 Growth inhibition assay Inhibition of human SW837 cell growth in a cell viability assay, IC50 = 0.02762 μM. SANGER
MDA-MB-231 Growth inhibition assay Inhibition of human MDA-MB-231 cell growth in a cell viability assay, IC50 = 0.02778 μM. SANGER
KYSE-140 Growth inhibition assay Inhibition of human KYSE-140 cell growth in a cell viability assay, IC50 = 0.02791 μM. SANGER
NOMO-1 Growth inhibition assay Inhibition of human NOMO-1 cell growth in a cell viability assay, IC50 = 0.02868 μM. SANGER
GP5d Growth inhibition assay Inhibition of human GP5d cell growth in a cell viability assay, IC50 = 0.02872 μM. SANGER
COR-L105 Growth inhibition assay Inhibition of human COR-L105 cell growth in a cell viability assay, IC50 = 0.02942 μM. SANGER
LS-411N Growth inhibition assay Inhibition of human LS-411N cell growth in a cell viability assay, IC50 = 0.02988 μM. SANGER
NY Growth inhibition assay Inhibition of human NY cell growth in a cell viability assay, IC50 = 0.03018 μM. SANGER
NCI-H2030 Growth inhibition assay Inhibition of human NCI-H2030 cell growth in a cell viability assay, IC50 = 0.03045 μM. SANGER
CCF-STTG1 Growth inhibition assay Inhibition of human CCF-STTG1 cell growth in a cell viability assay, IC50 = 0.03142 μM. SANGER
NCI-H1703 Growth inhibition assay Inhibition of human NCI-H1703 cell growth in a cell viability assay, IC50 = 0.03178 μM. SANGER
TUR Growth inhibition assay Inhibition of human TUR cell growth in a cell viability assay, IC50 = 0.03203 μM. SANGER
NOS-1 Growth inhibition assay Inhibition of human NOS-1 cell growth in a cell viability assay, IC50 = 0.03244 μM. SANGER
A2058 Growth inhibition assay Inhibition of human A2058 cell growth in a cell viability assay, IC50 = 0.03283 μM. SANGER
LCLC-103H Growth inhibition assay Inhibition of human LCLC-103H cell growth in a cell viability assay, IC50 = 0.03325 μM. SANGER
NCI-H510A Growth inhibition assay Inhibition of human NCI-H510A cell growth in a cell viability assay, IC50 = 0.03327 μM. SANGER
BC-1 Growth inhibition assay Inhibition of human BC-1 cell growth in a cell viability assay, IC50 = 0.03377 μM. SANGER
SK-CO-1 Growth inhibition assay Inhibition of human SK-CO-1 cell growth in a cell viability assay, IC50 = 0.03401 μM. SANGER
A673 Growth inhibition assay Inhibition of human A673 cell growth in a cell viability assay, IC50 = 0.03417 μM. SANGER
VM-CUB-1 Growth inhibition assay Inhibition of human VM-CUB-1 cell growth in a cell viability assay, IC50 = 0.03469 μM. SANGER
HH Growth inhibition assay Inhibition of human HH cell growth in a cell viability assay, IC50 = 0.03506 μM. SANGER
CAL-27 Growth inhibition assay Inhibition of human CAL-27 cell growth in a cell viability assay, IC50 = 0.03516 μM. SANGER
NEC8 Growth inhibition assay Inhibition of human NEC8 cell growth in a cell viability assay, IC50 = 0.03537 μM. SANGER
BxPC-3 Growth inhibition assay Inhibition of human BxPC-3 cell growth in a cell viability assay, IC50 = 0.03691 μM. SANGER
SNB75 Growth inhibition assay Inhibition of human SNB75 cell growth in a cell viability assay, IC50 = 0.03724 μM. SANGER
NB13 Growth inhibition assay Inhibition of human NB13 cell growth in a cell viability assay, IC50 = 0.03823 μM. SANGER
SK-OV-3 Growth inhibition assay Inhibition of human SK-OV-3 cell growth in a cell viability assay, IC50 = 0.03874 μM. SANGER
ME-180 Growth inhibition assay Inhibition of human ME-180 cell growth in a cell viability assay, IC50 = 0.0388 μM. SANGER
JiyoyeP-2003 Growth inhibition assay Inhibition of human JiyoyeP-2003 cell growth in a cell viability assay, IC50 = 0.03938 μM. SANGER
LU-134-A Growth inhibition assay Inhibition of human LU-134-A cell growth in a cell viability assay, IC50 = 0.04002 μM. SANGER
LS-123 Growth inhibition assay Inhibition of human LS-123 cell growth in a cell viability assay, IC50 = 0.04028 μM. SANGER
COLO-800 Growth inhibition assay Inhibition of human COLO-800 cell growth in a cell viability assay, IC50 = 0.04056 μM. SANGER
LB831-BLC Growth inhibition assay Inhibition of human LB831-BLC cell growth in a cell viability assay, IC50 = 0.04185 μM. SANGER
NCI-H747 Growth inhibition assay Inhibition of human NCI-H747 cell growth in a cell viability assay, IC50 = 0.04228 μM. SANGER
MZ7-mel Growth inhibition assay Inhibition of human MZ7-mel cell growth in a cell viability assay, IC50 = 0.04266 μM. SANGER
GT3TKB Growth inhibition assay Inhibition of human GT3TKB cell growth in a cell viability assay, IC50 = 0.04272 μM. SANGER
23132-87 Growth inhibition assay Inhibition of human 23132-87 cell growth in a cell viability assay, IC50 = 0.04305 μM. SANGER
MOLT-16 Growth inhibition assay Inhibition of human MOLT-16 cell growth in a cell viability assay, IC50 = 0.04305 μM. SANGER
PF-382 Growth inhibition assay Inhibition of human PF-382 cell growth in a cell viability assay, IC50 = 0.04422 μM. SANGER
ES3 Growth inhibition assay Inhibition of human ES3 cell growth in a cell viability assay, IC50 = 0.0446 μM. SANGER
SW756 Growth inhibition assay Inhibition of human SW756 cell growth in a cell viability assay, IC50 = 0.04514 μM. SANGER
OAW-28 Growth inhibition assay Inhibition of human OAW-28 cell growth in a cell viability assay, IC50 = 0.04536 μM. SANGER
RPMI-8402 Growth inhibition assay Inhibition of human RPMI-8402 cell growth in a cell viability assay, IC50 = 0.04593 μM. SANGER
NCI-H1693 Growth inhibition assay Inhibition of human NCI-H1693 cell growth in a cell viability assay, IC50 = 0.04609 μM. SANGER
MS-1 Growth inhibition assay Inhibition of human MS-1 cell growth in a cell viability assay, IC50 = 0.04634 μM. SANGER
WSU-NHL Growth inhibition assay Inhibition of human WSU-NHL cell growth in a cell viability assay, IC50 = 0.05035 μM. SANGER
HCT-116 Growth inhibition assay Inhibition of human HCT-116 cell growth in a cell viability assay, IC50 = 0.05083 μM. SANGER
SF295 Growth inhibition assay Inhibition of human SF295 cell growth in a cell viability assay, IC50 = 0.05112 μM. SANGER
MFE-296 Growth inhibition assay Inhibition of human MFE-296 cell growth in a cell viability assay, IC50 = 0.05135 μM. SANGER
NCI-H209 Growth inhibition assay Inhibition of human NCI-H209 cell growth in a cell viability assay, IC50 = 0.05207 μM. SANGER
SW962 Growth inhibition assay Inhibition of human SW962 cell growth in a cell viability assay, IC50 = 0.05241 μM. SANGER
CTB-1 Growth inhibition assay Inhibition of human CTB-1 cell growth in a cell viability assay, IC50 = 0.05339 μM. SANGER
EFO-21 Growth inhibition assay Inhibition of human EFO-21 cell growth in a cell viability assay, IC50 = 0.05366 μM. SANGER
A704 Growth inhibition assay Inhibition of human A704 cell growth in a cell viability assay, IC50 = 0.05378 μM. SANGER
COR-L279 Growth inhibition assay Inhibition of human COR-L279 cell growth in a cell viability assay, IC50 = 0.05391 μM. SANGER
HN Growth inhibition assay Inhibition of human HN cell growth in a cell viability assay, IC50 = 0.05409 μM. SANGER
Caov-3 Growth inhibition assay Inhibition of human Caov-3 cell growth in a cell viability assay, IC50 = 0.05413 μM. SANGER
NCI-H1770 Growth inhibition assay Inhibition of human NCI-H1770 cell growth in a cell viability assay, IC50 = 0.05504 μM. SANGER
G-401 Growth inhibition assay Inhibition of human G-401 cell growth in a cell viability assay, IC50 = 0.05516 μM. SANGER
KYSE-410 Growth inhibition assay Inhibition of human KYSE-410 cell growth in a cell viability assay, IC50 = 0.05587 μM. SANGER
OE33 Growth inhibition assay Inhibition of human OE33 cell growth in a cell viability assay, IC50 = 0.06117 μM. SANGER
NCI-H1694 Growth inhibition assay Inhibition of human NCI-H1694 cell growth in a cell viability assay, IC50 = 0.06129 μM. SANGER
KG-1 Growth inhibition assay Inhibition of human KG-1 cell growth in a cell viability assay, IC50 = 0.0622 μM. SANGER
SNU-423 Growth inhibition assay Inhibition of human SNU-423 cell growth in a cell viability assay, IC50 = 0.06248 μM. SANGER
GDM-1 Growth inhibition assay Inhibition of human GDM-1 cell growth in a cell viability assay, IC50 = 0.06254 μM. SANGER
SU-DHL-1 Growth inhibition assay Inhibition of human SU-DHL-1 cell growth in a cell viability assay, IC50 = 0.06266 μM. SANGER
LB2518-MEL Growth inhibition assay Inhibition of human LB2518-MEL cell growth in a cell viability assay, IC50 = 0.06452 μM. SANGER
LB996-RCC Growth inhibition assay Inhibition of human LB996-RCC cell growth in a cell viability assay, IC50 = 0.06509 μM. SANGER
MOLT-4 Growth inhibition assay Inhibition of human MOLT-4 cell growth in a cell viability assay, IC50 = 0.06528 μM. SANGER
J-RT3-T3-5 Growth inhibition assay Inhibition of human J-RT3-T3-5 cell growth in a cell viability assay, IC50 = 0.06718 μM. SANGER
HCC1599 Growth inhibition assay Inhibition of human HCC1599 cell growth in a cell viability assay, IC50 = 0.07022 μM. SANGER
TYK-nu Growth inhibition assay Inhibition of human TYK-nu cell growth in a cell viability assay, IC50 = 0.07264 μM. SANGER
EW-18 Growth inhibition assay Inhibition of human EW-18 cell growth in a cell viability assay, IC50 = 0.07275 μM. SANGER
LC4-1 Growth inhibition assay Inhibition of human LC4-1 cell growth in a cell viability assay, IC50 = 0.07474 μM. SANGER
COLO-680N Growth inhibition assay Inhibition of human COLO-680N cell growth in a cell viability assay, IC50 = 0.07549 μM. SANGER
MKN1 Growth inhibition assay Inhibition of human MKN1 cell growth in a cell viability assay, IC50 = 0.07837 μM. SANGER
HCT-15 Growth inhibition assay Inhibition of human HCT-15 cell growth in a cell viability assay, IC50 = 0.08216 μM. SANGER
NCI-H1882 Growth inhibition assay Inhibition of human NCI-H1882 cell growth in a cell viability assay, IC50 = 0.08245 μM. SANGER
IMR-5 Growth inhibition assay Inhibition of human IMR-5 cell growth in a cell viability assay, IC50 = 0.08296 μM. SANGER
DB Growth inhibition assay Inhibition of human DB cell growth in a cell viability assay, IC50 = 0.0844 μM. SANGER
P12-ICHIKAWA Growth inhibition assay Inhibition of human P12-ICHIKAWA cell growth in a cell viability assay, IC50 = 0.0847 μM. SANGER
KARPAS-422 Growth inhibition assay Inhibition of human KARPAS-422 cell growth in a cell viability assay, IC50 = 0.08579 μM. SANGER
SK-N-DZ Growth inhibition assay Inhibition of human SK-N-DZ cell growth in a cell viability assay, IC50 = 0.08656 μM. SANGER
FTC-133 Growth inhibition assay Inhibition of human FTC-133 cell growth in a cell viability assay, IC50 = 0.08749 μM. SANGER
SCC-3 Growth inhibition assay Inhibition of human SCC-3 cell growth in a cell viability assay, IC50 = 0.08964 μM. SANGER
KM12 Growth inhibition assay Inhibition of human KM12 cell growth in a cell viability assay, IC50 = 0.09149 μM. SANGER
OAW-42 Growth inhibition assay Inhibition of human OAW-42 cell growth in a cell viability assay, IC50 = 0.09214 μM. SANGER
GCIY Growth inhibition assay Inhibition of human GCIY cell growth in a cell viability assay, IC50 = 0.09269 μM. SANGER
KYSE-520 Growth inhibition assay Inhibition of human KYSE-520 cell growth in a cell viability assay, IC50 = 0.09284 μM. SANGER
RPMI-8866 Growth inhibition assay Inhibition of human RPMI-8866 cell growth in a cell viability assay, IC50 = 0.09523 μM. SANGER
L-363 Growth inhibition assay Inhibition of human L-363 cell growth in a cell viability assay, IC50 = 0.0955 μM. SANGER
22RV1 Growth inhibition assay Inhibition of human 22RV1 cell growth in a cell viability assay, IC50 = 0.09648 μM. SANGER
DSH1 Growth inhibition assay Inhibition of human DSH1 cell growth in a cell viability assay, IC50 = 0.0965 μM. SANGER
A253 Growth inhibition assay Inhibition of human A253 cell growth in a cell viability assay, IC50 = 0.10228 μM. SANGER
NCI-H661 Growth inhibition assay Inhibition of human NCI-H661 cell growth in a cell viability assay, IC50 = 0.10402 μM. SANGER
SK-MEL-3 Growth inhibition assay Inhibition of human SK-MEL-3 cell growth in a cell viability assay, IC50 = 0.1051 μM. SANGER
FADU Growth inhibition assay Inhibition of human FADU cell growth in a cell viability assay, IC50 = 0.10545 μM. SANGER
SJRH30 Growth inhibition assay Inhibition of human SJRH30 cell growth in a cell viability assay, IC50 = 0.10641 μM. SANGER
HCC1569 Growth inhibition assay Inhibition of human HCC1569 cell growth in a cell viability assay, IC50 = 0.10936 μM. SANGER
NCI-H526 Growth inhibition assay Inhibition of human NCI-H526 cell growth in a cell viability assay, IC50 = 0.10988 μM. SANGER
BL-70 Growth inhibition assay Inhibition of human BL-70 cell growth in a cell viability assay, IC50 = 0.11097 μM. SANGER
SW1990 Growth inhibition assay Inhibition of human SW1990 cell growth in a cell viability assay, IC50 = 0.11307 μM. SANGER
LAMA-84 Growth inhibition assay Inhibition of human LAMA-84 cell growth in a cell viability assay, IC50 = 0.11504 μM. SANGER
COLO-741 Growth inhibition assay Inhibition of human COLO-741 cell growth in a cell viability assay, IC50 = 0.12012 μM. SANGER
SCC-15 Growth inhibition assay Inhibition of human SCC-15 cell growth in a cell viability assay, IC50 = 0.12113 μM. SANGER
DBTRG-05MG Growth inhibition assay Inhibition of human DBTRG-05MG cell growth in a cell viability assay, IC50 = 0.12182 μM. SANGER
HEC-1 Growth inhibition assay Inhibition of human HEC-1 cell growth in a cell viability assay, IC50 = 0.12363 μM. SANGER
D-283MED Growth inhibition assay Inhibition of human D-283MED cell growth in a cell viability assay, IC50 = 0.12698 μM. SANGER
RD Growth inhibition assay Inhibition of human RD cell growth in a cell viability assay, IC50 = 0.13011 μM. SANGER
K052 Growth inhibition assay Inhibition of human K052 cell growth in a cell viability assay, IC50 = 0.13671 μM. SANGER
CAL-85-1 Growth inhibition assay Inhibition of human CAL-85-1 cell growth in a cell viability assay, IC50 = 0.14463 μM. SANGER
NCI-H2052 Growth inhibition assay Inhibition of human NCI-H2052 cell growth in a cell viability assay, IC50 = 0.14482 μM. SANGER
BFTC-909 Growth inhibition assay Inhibition of human BFTC-909 cell growth in a cell viability assay, IC50 = 0.1456 μM. SANGER
HuP-T3 Growth inhibition assay Inhibition of human HuP-T3 cell growth in a cell viability assay, IC50 = 0.14565 μM. SANGER
NCI-H64 Growth inhibition assay Inhibition of human NCI-H64 cell growth in a cell viability assay, IC50 = 0.15093 μM. SANGER
C-4-II Growth inhibition assay Inhibition of human C-4-II cell growth in a cell viability assay, IC50 = 0.15237 μM. SANGER
KMOE-2 Growth inhibition assay Inhibition of human KMOE-2 cell growth in a cell viability assay, IC50 = 0.15493 μM. SANGER
NB12 Growth inhibition assay Inhibition of human NB12 cell growth in a cell viability assay, IC50 = 0.15515 μM. SANGER
EM-2 Growth inhibition assay Inhibition of human EM-2 cell growth in a cell viability assay, IC50 = 0.1599 μM. SANGER
SIMA Growth inhibition assay Inhibition of human SIMA cell growth in a cell viability assay, IC50 = 0.16125 μM. SANGER
SBC-1 Growth inhibition assay Inhibition of human SBC-1 cell growth in a cell viability assay, IC50 = 0.16557 μM. SANGER
KS-1 Growth inhibition assay Inhibition of human KS-1 cell growth in a cell viability assay, IC50 = 0.16652 μM. SANGER
no-10 Growth inhibition assay Inhibition of human no-10 cell growth in a cell viability assay, IC50 = 0.17376 μM. SANGER
NCCIT Growth inhibition assay Inhibition of human NCCIT cell growth in a cell viability assay, IC50 = 0.17626 μM. SANGER
RERF-LC-MS Growth inhibition assay Inhibition of human RERF-LC-MS cell growth in a cell viability assay, IC50 = 0.17669 μM. SANGER
BT-20 Growth inhibition assay Inhibition of human BT-20 cell growth in a cell viability assay, IC50 = 0.18174 μM. SANGER
NCI-H1623 Growth inhibition assay Inhibition of human NCI-H1623 cell growth in a cell viability assay, IC50 = 0.18708 μM. SANGER
TE-9 Growth inhibition assay Inhibition of human TE-9 cell growth in a cell viability assay, IC50 = 0.18963 μM. SANGER
U-87-MG Growth inhibition assay Inhibition of human U-87-MG cell growth in a cell viability assay, IC50 = 0.19057 μM. SANGER
CAL-51 Growth inhibition assay Inhibition of human CAL-51 cell growth in a cell viability assay, IC50 = 0.19114 μM. SANGER
639-V Growth inhibition assay Inhibition of human 639-V cell growth in a cell viability assay, IC50 = 0.19314 μM. SANGER
SJSA-1 Growth inhibition assay Inhibition of human SJSA-1 cell growth in a cell viability assay, IC50 = 0.19501 μM. SANGER
DOHH-2 Growth inhibition assay Inhibition of human DOHH-2 cell growth in a cell viability assay, IC50 = 0.19564 μM. SANGER
IST-SL1 Growth inhibition assay Inhibition of human IST-SL1 cell growth in a cell viability assay, IC50 = 0.19747 μM. SANGER
NCI-H1618 Growth inhibition assay Inhibition of human NCI-H1618 cell growth in a cell viability assay, IC50 = 0.19756 μM. SANGER
TGW Growth inhibition assay Inhibition of human TGW cell growth in a cell viability assay, IC50 = 0.19964 μM. SANGER
HT-3 Growth inhibition assay Inhibition of human HT-3 cell growth in a cell viability assay, IC50 = 0.20054 μM. SANGER
AN3-CA Growth inhibition assay Inhibition of human AN3-CA cell growth in a cell viability assay, IC50 = 0.20329 μM. SANGER
PC-14 Growth inhibition assay Inhibition of human PC-14 cell growth in a cell viability assay, IC50 = 0.20331 μM. SANGER
BHT-101 Growth inhibition assay Inhibition of human BHT-101 cell growth in a cell viability assay, IC50 = 0.21039 μM. SANGER
NCI-H23 Growth inhibition assay Inhibition of human NCI-H23 cell growth in a cell viability assay, IC50 = 0.21106 μM. SANGER
SCC-4 Growth inhibition assay Inhibition of human SCC-4 cell growth in a cell viability assay, IC50 = 0.21185 μM. SANGER
EGI-1 Growth inhibition assay Inhibition of human EGI-1 cell growth in a cell viability assay, IC50 = 0.21386 μM. SANGER
Calu-1 Growth inhibition assay Inhibition of human Calu-1 cell growth in a cell viability assay, IC50 = 0.22003 μM. SANGER
BC-3 Growth inhibition assay Inhibition of human BC-3 cell growth in a cell viability assay, IC50 = 0.22065 μM. SANGER
HOP-62 Growth inhibition assay Inhibition of human HOP-62 cell growth in a cell viability assay, IC50 = 0.22258 μM. SANGER
NCI-H1793 Growth inhibition assay Inhibition of human NCI-H1793 cell growth in a cell viability assay, IC50 = 0.22363 μM. SANGER
COLO-320-HSR Growth inhibition assay Inhibition of human COLO-320-HSR cell growth in a cell viability assay, IC50 = 0.22408 μM. SANGER
NCI-H596 Growth inhibition assay Inhibition of human NCI-H596 cell growth in a cell viability assay, IC50 = 0.22513 μM. SANGER
EHEB Growth inhibition assay Inhibition of human EHEB cell growth in a cell viability assay, IC50 = 0.22651 μM. SANGER
BEN Growth inhibition assay Inhibition of human BEN cell growth in a cell viability assay, IC50 = 0.23791 μM. SANGER
MHH-PREB-1 Growth inhibition assay Inhibition of human MHH-PREB-1 cell growth in a cell viability assay, IC50 = 0.24804 μM. SANGER
TE-6 Growth inhibition assay Inhibition of human TE-6 cell growth in a cell viability assay, IC50 = 0.25035 μM. SANGER
KARPAS-299 Growth inhibition assay Inhibition of human KARPAS-299 cell growth in a cell viability assay, IC50 = 0.252 μM. SANGER
BOKU Growth inhibition assay Inhibition of human BOKU cell growth in a cell viability assay, IC50 = 0.25433 μM. SANGER
MZ1-PC Growth inhibition assay Inhibition of human MZ1-PC cell growth in a cell viability assay, IC50 = 0.25435 μM. SANGER
IPC-298 Growth inhibition assay Inhibition of human IPC-298 cell growth in a cell viability assay, IC50 = 0.25477 μM. SANGER
NCI-H1792 Growth inhibition assay Inhibition of human NCI-H1792 cell growth in a cell viability assay, IC50 = 0.25904 μM. SANGER
KM-H2 Growth inhibition assay Inhibition of human KM-H2 cell growth in a cell viability assay, IC50 = 0.26068 μM. SANGER
Becker Growth inhibition assay Inhibition of human Becker cell growth in a cell viability assay, IC50 = 0.26704 μM. SANGER
NCI-H446 Growth inhibition assay Inhibition of human NCI-H446 cell growth in a cell viability assay, IC50 = 0.26911 μM. SANGER
MLMA Growth inhibition assay Inhibition of human MLMA cell growth in a cell viability assay, IC50 = 0.27156 μM. SANGER
JEG-3 Growth inhibition assay Inhibition of human JEG-3 cell growth in a cell viability assay, IC50 = 0.27669 μM. SANGER
SCC-25 Growth inhibition assay Inhibition of human SCC-25 cell growth in a cell viability assay, IC50 = 0.28928 μM. SANGER
CA46 Growth inhibition assay Inhibition of human CA46 cell growth in a cell viability assay, IC50 = 0.29339 μM. SANGER
CAL-54 Growth inhibition assay Inhibition of human CAL-54 cell growth in a cell viability assay, IC50 = 0.29759 μM. SANGER
KYSE-70 Growth inhibition assay Inhibition of human KYSE-70 cell growth in a cell viability assay, IC50 = 0.29969 μM. SANGER
LU-65 Growth inhibition assay Inhibition of human LU-65 cell growth in a cell viability assay, IC50 = 0.30381 μM. SANGER
OVCAR-5 Growth inhibition assay Inhibition of human OVCAR-5 cell growth in a cell viability assay, IC50 = 0.30577 μM. SANGER
NCI-H2081 Growth inhibition assay Inhibition of human NCI-H2081 cell growth in a cell viability assay, IC50 = 0.31077 μM. SANGER
NCI-H226 Growth inhibition assay Inhibition of human NCI-H226 cell growth in a cell viability assay, IC50 = 0.31696 μM. SANGER
A427 Growth inhibition assay Inhibition of human A427 cell growth in a cell viability assay, IC50 = 0.32398 μM. SANGER
CPC-N Growth inhibition assay Inhibition of human CPC-N cell growth in a cell viability assay, IC50 = 0.329 μM. SANGER
SW13 Growth inhibition assay Inhibition of human SW13 cell growth in a cell viability assay, IC50 = 0.33037 μM. SANGER
K-562 Growth inhibition assay Inhibition of human K-562 cell growth in a cell viability assay, IC50 = 0.33298 μM. SANGER
NCI-N87 Growth inhibition assay Inhibition of human NCI-N87 cell growth in a cell viability assay, IC50 = 0.33304 μM. SANGER
U-698-M Growth inhibition assay Inhibition of human U-698-M cell growth in a cell viability assay, IC50 = 0.34453 μM. SANGER
IM-9 Growth inhibition assay Inhibition of human IM-9 cell growth in a cell viability assay, IC50 = 0.34691 μM. SANGER
NCI-H748 Growth inhibition assay Inhibition of human NCI-H748 cell growth in a cell viability assay, IC50 = 0.35458 μM. SANGER
UACC-257 Growth inhibition assay Inhibition of human UACC-257 cell growth in a cell viability assay, IC50 = 0.36412 μM. SANGER
HT-1376 Growth inhibition assay Inhibition of human HT-1376 cell growth in a cell viability assay, IC50 = 0.36895 μM. SANGER
GAK Growth inhibition assay Inhibition of human GAK cell growth in a cell viability assay, IC50 = 0.37294 μM. SANGER
NCI-H82 Growth inhibition assay Inhibition of human NCI-H82 cell growth in a cell viability assay, IC50 = 0.37297 μM. SANGER
NCI-H1304 Growth inhibition assay Inhibition of human NCI-H1304 cell growth in a cell viability assay, IC50 = 0.38454 μM. SANGER
MHH-NB-11 Growth inhibition assay Inhibition of human MHH-NB-11 cell growth in a cell viability assay, IC50 = 0.38597 μM. SANGER
CAMA-1 Growth inhibition assay Inhibition of human CAMA-1 cell growth in a cell viability assay, IC50 = 0.3958 μM. SANGER
GCT Growth inhibition assay Inhibition of human GCT cell growth in a cell viability assay, IC50 = 0.4051 μM. SANGER
HPAF-II Growth inhibition assay Inhibition of human HPAF-II cell growth in a cell viability assay, IC50 = 0.42847 μM. SANGER
Raji Growth inhibition assay Inhibition of human Raji cell growth in a cell viability assay, IC50 = 0.43145 μM. SANGER
EW-11 Growth inhibition assay Inhibition of human EW-11 cell growth in a cell viability assay, IC50 = 0.43352 μM. SANGER
SW1573 Growth inhibition assay Inhibition of human SW1573 cell growth in a cell viability assay, IC50 = 0.45733 μM. SANGER
KLE Growth inhibition assay Inhibition of human KLE cell growth in a cell viability assay, IC50 = 0.45942 μM. SANGER
NCI-H69 Growth inhibition assay Inhibition of human NCI-H69 cell growth in a cell viability assay, IC50 = 0.45948 μM. SANGER
MDA-MB-361 Growth inhibition assay Inhibition of human MDA-MB-361 cell growth in a cell viability assay, IC50 = 0.46064 μM. SANGER
SW48 Growth inhibition assay Inhibition of human SW48 cell growth in a cell viability assay, IC50 = 0.46259 μM. SANGER
SK-MM-2 Growth inhibition assay Inhibition of human SK-MM-2 cell growth in a cell viability assay, IC50 = 0.47912 μM. SANGER
MC116 Growth inhibition assay Inhibition of human MC116 cell growth in a cell viability assay, IC50 = 0.48166 μM. SANGER
NB1 Growth inhibition assay Inhibition of human NB1 cell growth in a cell viability assay, IC50 = 0.48753 μM. SANGER
NCI-H1155 Growth inhibition assay Inhibition of human NCI-H1155 cell growth in a cell viability assay, IC50 = 0.48828 μM. SANGER
SN12C Growth inhibition assay Inhibition of human SN12C cell growth in a cell viability assay, IC50 = 0.49734 μM. SANGER
NCI-H838 Growth inhibition assay Inhibition of human NCI-H838 cell growth in a cell viability assay, IC50 = 0.49875 μM. SANGER
SW1463 Growth inhibition assay Inhibition of human SW1463 cell growth in a cell viability assay, IC50 = 0.51017 μM. SANGER
NCI-H1648 Growth inhibition assay Inhibition of human NCI-H1648 cell growth in a cell viability assay, IC50 = 0.51081 μM. SANGER
M14 Growth inhibition assay Inhibition of human M14 cell growth in a cell viability assay, IC50 = 0.51466 μM. SANGER
T98G Growth inhibition assay Inhibition of human T98G cell growth in a cell viability assay, IC50 = 0.53948 μM. SANGER
CaR-1 Growth inhibition assay Inhibition of human CaR-1 cell growth in a cell viability assay, IC50 = 0.55122 μM. SANGER
NCI-H650 Growth inhibition assay Inhibition of human NCI-H650 cell growth in a cell viability assay, IC50 = 0.56569 μM. SANGER
HuH-7 Growth inhibition assay Inhibition of human HuH-7 cell growth in a cell viability assay, IC50 = 0.56861 μM. SANGER
Daudi Growth inhibition assay Inhibition of human Daudi cell growth in a cell viability assay, IC50 = 0.56949 μM. SANGER
CAL-120 Growth inhibition assay Inhibition of human CAL-120 cell growth in a cell viability assay, IC50 = 0.57588 μM. SANGER
EW-3 Growth inhibition assay Inhibition of human EW-3 cell growth in a cell viability assay, IC50 = 0.57956 μM. SANGER
OMC-1 Growth inhibition assay Inhibition of human OMC-1 cell growth in a cell viability assay, IC50 = 0.58333 μM. SANGER
U-266 Growth inhibition assay Inhibition of human U-266 cell growth in a cell viability assay, IC50 = 0.60794 μM. SANGER
OVCAR-4 Growth inhibition assay Inhibition of human OVCAR-4 cell growth in a cell viability assay, IC50 = 0.62523 μM. SANGER
RCC10RGB Growth inhibition assay Inhibition of human RCC10RGB cell growth in a cell viability assay, IC50 = 0.63374 μM. SANGER
NCI-H2141 Growth inhibition assay Inhibition of human NCI-H2141 cell growth in a cell viability assay, IC50 = 0.64404 μM. SANGER
Ramos-2G6-4C10 Growth inhibition assay Inhibition of human Ramos-2G6-4C10 cell growth in a cell viability assay, IC50 = 0.66087 μM. SANGER
THP-1 Growth inhibition assay Inhibition of human THP-1 cell growth in a cell viability assay, IC50 = 0.6642 μM. SANGER
RCM-1 Growth inhibition assay Inhibition of human RCM-1 cell growth in a cell viability assay, IC50 = 0.66478 μM. SANGER
K5 Growth inhibition assay Inhibition of human K5 cell growth in a cell viability assay, IC50 = 0.68269 μM. SANGER
MPP-89 Growth inhibition assay Inhibition of human MPP-89 cell growth in a cell viability assay, IC50 = 0.69228 μM. SANGER
ChaGo-K-1 Growth inhibition assay Inhibition of human ChaGo-K-1 cell growth in a cell viability assay, IC50 = 0.6956 μM. SANGER
OE19 Growth inhibition assay Inhibition of human OE19 cell growth in a cell viability assay, IC50 = 0.70216 μM. SANGER
NCI-H1755 Growth inhibition assay Inhibition of human NCI-H1755 cell growth in a cell viability assay, IC50 = 0.71816 μM. SANGER
KNS-42 Growth inhibition assay Inhibition of human KNS-42 cell growth in a cell viability assay, IC50 = 0.73582 μM. SANGER
no-11 Growth inhibition assay Inhibition of human no-11 cell growth in a cell viability assay, IC50 = 0.73668 μM. SANGER
IST-MES1 Growth inhibition assay Inhibition of human IST-MES1 cell growth in a cell viability assay, IC50 = 0.77354 μM. SANGER
NCI-H2347 Growth inhibition assay Inhibition of human NCI-H2347 cell growth in a cell viability assay, IC50 = 0.79201 μM. SANGER
SKG-IIIa Growth inhibition assay Inhibition of human SKG-IIIa cell growth in a cell viability assay, IC50 = 0.80972 μM. SANGER
UACC-62 Growth inhibition assay Inhibition of human UACC-62 cell growth in a cell viability assay, IC50 = 0.8126 μM. SANGER
SNU-387 Growth inhibition assay Inhibition of human SNU-387 cell growth in a cell viability assay, IC50 = 0.82744 μM. SANGER
LS-513 Growth inhibition assay Inhibition of human LS-513 cell growth in a cell viability assay, IC50 = 0.88761 μM. SANGER
NCI-H719 Growth inhibition assay Inhibition of human NCI-H719 cell growth in a cell viability assay, IC50 = 0.89157 μM. SANGER
HOP-92 Growth inhibition assay Inhibition of human HOP-92 cell growth in a cell viability assay, IC50 = 0.95075 μM. SANGER
CAS-1 Growth inhibition assay Inhibition of human CAS-1 cell growth in a cell viability assay, IC50 = 0.95508 μM. SANGER
HTC-C3 Growth inhibition assay Inhibition of human HTC-C3 cell growth in a cell viability assay, IC50 = 0.9965 μM. SANGER
D-392MG Growth inhibition assay Inhibition of human D-392MG cell growth in a cell viability assay, IC50 = 1.02288 μM. SANGER
MHH-CALL-2 Growth inhibition assay Inhibition of human MHH-CALL-2 cell growth in a cell viability assay, IC50 = 1.02319 μM. SANGER
DMS-53 Growth inhibition assay Inhibition of human DMS-53 cell growth in a cell viability assay, IC50 = 1.03815 μM. SANGER
TGBC24TKB Growth inhibition assay Inhibition of human TGBC24TKB cell growth in a cell viability assay, IC50 = 1.04183 μM. SANGER
NCI-H1417 Growth inhibition assay Inhibition of human NCI-H1417 cell growth in a cell viability assay, IC50 = 1.07075 μM. SANGER
OVCAR-3 Growth inhibition assay Inhibition of human OVCAR-3 cell growth in a cell viability assay, IC50 = 1.0739 μM. SANGER
RXF393 Growth inhibition assay Inhibition of human RXF393 cell growth in a cell viability assay, IC50 = 1.1432 μM. SANGER
MKN28 Growth inhibition assay Inhibition of human MKN28 cell growth in a cell viability assay, IC50 = 1.15124 μM. SANGER
MSTO-211H Growth inhibition assay Inhibition of human MSTO-211H cell growth in a cell viability assay, IC50 = 1.15257 μM. SANGER
NCI-H2126 Growth inhibition assay Inhibition of human NCI-H2126 cell growth in a cell viability assay, IC50 = 1.15799 μM. SANGER
TCCSUP Growth inhibition assay Inhibition of human TCCSUP cell growth in a cell viability assay, IC50 = 1.16785 μM. SANGER
TE-12 Growth inhibition assay Inhibition of human TE-12 cell growth in a cell viability assay, IC50 = 1.17366 μM. SANGER
NCI-H1581 Growth inhibition assay Inhibition of human NCI-H1581 cell growth in a cell viability assay, IC50 = 1.17372 μM. SANGER
GOTO Growth inhibition assay Inhibition of human GOTO cell growth in a cell viability assay, IC50 = 1.20277 μM. SANGER
NCI-H28 Growth inhibition assay Inhibition of human NCI-H28 cell growth in a cell viability assay, IC50 = 1.2149 μM. SANGER
KNS-81-FD Growth inhibition assay Inhibition of human KNS-81-FD cell growth in a cell viability assay, IC50 = 1.23463 μM. SANGER
YT Growth inhibition assay Inhibition of human YT cell growth in a cell viability assay, IC50 = 1.28559 μM. SANGER
NB5 Growth inhibition assay Inhibition of human NB5 cell growth in a cell viability assay, IC50 = 1.32585 μM. SANGER
U-118-MG Growth inhibition assay Inhibition of human U-118-MG cell growth in a cell viability assay, IC50 = 1.35159 μM. SANGER
LS-1034 Growth inhibition assay Inhibition of human LS-1034 cell growth in a cell viability assay, IC50 = 1.3845 μM. SANGER
PANC-08-13 Growth inhibition assay Inhibition of human PANC-08-13 cell growth in a cell viability assay, IC50 = 1.39613 μM. SANGER
COLO-205 Growth inhibition assay Inhibition of human COLO-205 cell growth in a cell viability assay, IC50 = 1.47181 μM. SANGER
KURAMOCHI Growth inhibition assay Inhibition of human KURAMOCHI cell growth in a cell viability assay, IC50 = 1.49739 μM. SANGER
SNU-C2B Growth inhibition assay Inhibition of human SNU-C2B cell growth in a cell viability assay, IC50 = 1.54777 μM. SANGER
HDLM-2 Growth inhibition assay Inhibition of human HDLM-2 cell growth in a cell viability assay, IC50 = 1.63327 μM. SANGER
PFSK-1 Growth inhibition assay Inhibition of human PFSK-1 cell growth in a cell viability assay, IC50 = 1.64794 μM. SANGER
SW1088 Growth inhibition assay Inhibition of human SW1088 cell growth in a cell viability assay, IC50 = 1.66167 μM. SANGER
LB373-MEL-D Growth inhibition assay Inhibition of human LB373-MEL-D cell growth in a cell viability assay, IC50 = 1.66495 μM. SANGER
HT-1197 Growth inhibition assay Inhibition of human HT-1197 cell growth in a cell viability assay, IC50 = 1.76425 μM. SANGER
MMAC-SF Growth inhibition assay Inhibition of human MMAC-SF cell growth in a cell viability assay, IC50 = 1.7766 μM. SANGER
T-24 Growth inhibition assay Inhibition of human T-24 cell growth in a cell viability assay, IC50 = 2.07629 μM. SANGER
LK-2 Growth inhibition assay Inhibition of human LK-2 cell growth in a cell viability assay, IC50 = 2.08563 μM. SANGER
5637 Growth inhibition assay Inhibition of human 5637 cell growth in a cell viability assay, IC50 = 2.10298 μM. SANGER
GI-ME-N Growth inhibition assay Inhibition of human GI-ME-N cell growth in a cell viability assay, IC50 = 2.10851 μM. SANGER
NCI-H2196 Growth inhibition assay Inhibition of human NCI-H2196 cell growth in a cell viability assay, IC50 = 2.31034 μM. SANGER
KOSC-2 Growth inhibition assay Inhibition of human KOSC-2 cell growth in a cell viability assay, IC50 = 2.35338 μM. SANGER
MN-60 Growth inhibition assay Inhibition of human MN-60 cell growth in a cell viability assay, IC50 = 2.43457 μM. SANGER
AsPC-1 Growth inhibition assay Inhibition of human AsPC-1 cell growth in a cell viability assay, IC50 = 2.50301 μM. SANGER
MDA-MB-175-VII Growth inhibition assay Inhibition of human MDA-MB-175-VII cell growth in a cell viability assay, IC50 = 2.51493 μM. SANGER
DG-75 Growth inhibition assay Inhibition of human DG-75 cell growth in a cell viability assay, IC50 = 2.5612 μM. SANGER
LNCaP-Clone-FGC Growth inhibition assay Inhibition of human LNCaP-Clone-FGC cell growth in a cell viability assay, IC50 = 2.65415 μM. SANGER
SCLC-21H Growth inhibition assay Inhibition of human SCLC-21H cell growth in a cell viability assay, IC50 = 2.77414 μM. SANGER
EFE-184 Growth inhibition assay Inhibition of human EFE-184 cell growth in a cell viability assay, IC50 = 2.79042 μM. SANGER
HCC2157 Growth inhibition assay Inhibition of human HCC2157 cell growth in a cell viability assay, IC50 = 2.80678 μM. SANGER
NCI-H1573 Growth inhibition assay Inhibition of human NCI-H1573 cell growth in a cell viability assay, IC50 = 2.80723 μM. SANGER
PC-3 Growth inhibition assay Inhibition of human PC-3 cell growth in a cell viability assay, IC50 = 2.83163 μM. SANGER
KY821 Growth inhibition assay Inhibition of human KY821 cell growth in a cell viability assay, IC50 = 2.8814 μM. SANGER
ECC4 Growth inhibition assay Inhibition of human ECC4 cell growth in a cell viability assay, IC50 = 2.92765 μM. SANGER
SK-N-AS Growth inhibition assay Inhibition of human SK-N-AS cell growth in a cell viability assay, IC50 = 2.96758 μM. SANGER
NB6 Growth inhibition assay Inhibition of human NB6 cell growth in a cell viability assay, IC50 = 3.2819 μM. SANGER
KMS-12-PE Growth inhibition assay Inhibition of human KMS-12-PE cell growth in a cell viability assay, IC50 = 3.55998 μM. SANGER
NCI-H2171 Growth inhibition assay Inhibition of human NCI-H2171 cell growth in a cell viability assay, IC50 = 3.76535 μM. SANGER
TE-11 Growth inhibition assay Inhibition of human TE-11 cell growth in a cell viability assay, IC50 = 4.09997 μM. SANGER
DMS-153 Growth inhibition assay Inhibition of human DMS-153 cell growth in a cell viability assay, IC50 = 4.10246 μM. SANGER
RVH-421 Growth inhibition assay Inhibition of human RVH-421 cell growth in a cell viability assay, IC50 = 4.11559 μM. SANGER
RO82-W-1 Growth inhibition assay Inhibition of human RO82-W-1 cell growth in a cell viability assay, IC50 = 4.42356 μM. SANGER
TE-1 Growth inhibition assay Inhibition of human TE-1 cell growth in a cell viability assay, IC50 = 5.86741 μM. SANGER
MFE-280 Growth inhibition assay Inhibition of human MFE-280 cell growth in a cell viability assay, IC50 = 5.90388 μM. SANGER
HT Growth inhibition assay Inhibition of human HT cell growth in a cell viability assay, IC50 = 5.93153 μM. SANGER
NCI-H1963 Growth inhibition assay Inhibition of human NCI-H1963 cell growth in a cell viability assay, IC50 = 6.26713 μM. SANGER
S-117 Growth inhibition assay Inhibition of human S-117 cell growth in a cell viability assay, IC50 = 6.30327 μM. SANGER
TGBC1TKB Growth inhibition assay Inhibition of human TGBC1TKB cell growth in a cell viability assay, IC50 = 6.51712 μM. SANGER
NCI-H1522 Growth inhibition assay Inhibition of human NCI-H1522 cell growth in a cell viability assay, IC50 = 6.53336 μM. SANGER
TE-441-T Growth inhibition assay Inhibition of human TE-441-T cell growth in a cell viability assay, IC50 = 6.5501 μM. SANGER
UACC-893 Growth inhibition assay Inhibition of human UACC-893 cell growth in a cell viability assay, IC50 = 6.55203 μM. SANGER
SHP-77 Growth inhibition assay Inhibition of human SHP-77 cell growth in a cell viability assay, IC50 = 6.85463 μM. SANGER
TALL-1 Growth inhibition assay Inhibition of human TALL-1 cell growth in a cell viability assay, IC50 = 7.00001 μM. SANGER
T47D Growth inhibition assay Inhibition of human T47D cell growth in a cell viability assay, IC50 = 7.00094 μM. SANGER
Capan-2 Growth inhibition assay Inhibition of human Capan-2 cell growth in a cell viability assay, IC50 = 7.09987 μM. SANGER
SK-MEL-2 Growth inhibition assay Inhibition of human SK-MEL-2 cell growth in a cell viability assay, IC50 = 7.13094 μM. SANGER
NCI-H1092 Growth inhibition assay Inhibition of human NCI-H1092 cell growth in a cell viability assay, IC50 = 7.15535 μM. SANGER
LP-1 Growth inhibition assay Inhibition of human LP-1 cell growth in a cell viability assay, IC50 = 7.30969 μM. SANGER
NCI-H889 Growth inhibition assay Inhibition of human NCI-H889 cell growth in a cell viability assay, IC50 = 7.57024 μM. SANGER
NCI-H2452 Growth inhibition assay Inhibition of human NCI-H2452 cell growth in a cell viability assay, IC50 = 7.63456 μM. SANGER
UMC-11 Growth inhibition assay Inhibition of human UMC-11 cell growth in a cell viability assay, IC50 = 8.35939 μM. SANGER
LU-165 Growth inhibition assay Inhibition of human LU-165 cell growth in a cell viability assay, IC50 = 8.41085 μM. SANGER
Mewo Growth inhibition assay Inhibition of human Mewo cell growth in a cell viability assay, IC50 = 8.43715 μM. SANGER
C32 Growth inhibition assay Inhibition of human C32 cell growth in a cell viability assay, IC50 = 8.43927 μM. SANGER
DV-90 Growth inhibition assay Inhibition of human DV-90 cell growth in a cell viability assay, IC50 = 8.45559 μM. SANGER
SW1417 Growth inhibition assay Inhibition of human SW1417 cell growth in a cell viability assay, IC50 = 8.63434 μM. SANGER
NCI-H187 Growth inhibition assay Inhibition of human NCI-H187 cell growth in a cell viability assay, IC50 = 8.85234 μM. SANGER
LU-99A Growth inhibition assay Inhibition of human LU-99A cell growth in a cell viability assay, IC50 = 9.13742 μM. SANGER
DMS-79 Growth inhibition assay Inhibition of human DMS-79 cell growth in a cell viability assay, IC50 = 9.4013 μM. SANGER
MDA-MB-415 Growth inhibition assay Inhibition of human MDA-MB-415 cell growth in a cell viability assay, IC50 = 9.95336 μM. SANGER
HCC1954 Growth inhibition assay Inhibition of human HCC1954 cell growth in a cell viability assay, IC50 = 9.97404 μM. SANGER
EB-3 Growth inhibition assay Inhibition of human EB-3 cell growth in a cell viability assay, IC50 = 11.1641 μM. SANGER
CW-2 Growth inhibition assay Inhibition of human CW-2 cell growth in a cell viability assay, IC50 = 11.2237 μM. SANGER
COR-L88 Growth inhibition assay Inhibition of human COR-L88 cell growth in a cell viability assay, IC50 = 11.4887 μM. SANGER
CP50-MEL-B Growth inhibition assay Inhibition of human CP50-MEL-B cell growth in a cell viability assay, IC50 = 11.567 μM. SANGER
LN-405 Growth inhibition assay Inhibition of human LN-405 cell growth in a cell viability assay, IC50 = 11.8448 μM. SANGER
EVSA-T Growth inhibition assay Inhibition of human EVSA-T cell growth in a cell viability assay, IC50 = 11.9609 μM. SANGER
HCC70 Growth inhibition assay Inhibition of human HCC70 cell growth in a cell viability assay, IC50 = 12.0511 μM. SANGER
UACC-812 Growth inhibition assay Inhibition of human UACC-812 cell growth in a cell viability assay, IC50 = 13.3687 μM. SANGER
LC-1F Growth inhibition assay Inhibition of human LC-1F cell growth in a cell viability assay, IC50 = 13.4575 μM. SANGER
HCC1419 Growth inhibition assay Inhibition of human HCC1419 cell growth in a cell viability assay, IC50 = 13.5715 μM. SANGER
C2BBe1 Growth inhibition assay Inhibition of human C2BBe1 cell growth in a cell viability assay, IC50 = 13.6612 μM. SANGER
COLO-678 Growth inhibition assay Inhibition of human COLO-678 cell growth in a cell viability assay, IC50 = 13.7484 μM. SANGER
RT4 Growth inhibition assay Inhibition of human RT4 cell growth in a cell viability assay, IC50 = 13.8428 μM. SANGER
NCI-H524 Growth inhibition assay Inhibition of human NCI-H524 cell growth in a cell viability assay, IC50 = 15.3769 μM. SANGER
HCC1143 Growth inhibition assay Inhibition of human HCC1143 cell growth in a cell viability assay, IC50 = 16.3541 μM. SANGER
HT55 Growth inhibition assay Inhibition of human HT55 cell growth in a cell viability assay, IC50 = 16.4103 μM. SANGER
CAL-39 Growth inhibition assay Inhibition of human CAL-39 cell growth in a cell viability assay, IC50 = 16.6227 μM. SANGER
KU-19-19 Growth inhibition assay Inhibition of human KU-19-19 cell growth in a cell viability assay, IC50 = 16.8123 μM. SANGER
LB771-HNC Growth inhibition assay Inhibition of human LB771-HNC cell growth in a cell viability assay, IC50 = 16.9876 μM. SANGER
OPM-2 Growth inhibition assay Inhibition of human OPM-2 cell growth in a cell viability assay, IC50 = 17.6337 μM. SANGER
CAKI-1 Growth inhibition assay Inhibition of human CAKI-1 cell growth in a cell viability assay, IC50 = 18.0406 μM. SANGER
KP-N-YN Growth inhibition assay Inhibition of human KP-N-YN cell growth in a cell viability assay, IC50 = 18.8885 μM. SANGER
SW948 Growth inhibition assay Inhibition of human SW948 cell growth in a cell viability assay, IC50 = 20.4975 μM. SANGER
SK-MEL-1 Growth inhibition assay Inhibition of human SK-MEL-1 cell growth in a cell viability assay, IC50 = 20.6083 μM. SANGER
NCI-H1563 Growth inhibition assay Inhibition of human NCI-H1563 cell growth in a cell viability assay, IC50 = 21.5347 μM. SANGER
GMS-10 Growth inhibition assay Inhibition of human GMS-10 cell growth in a cell viability assay, IC50 = 21.6061 μM. SANGER
MDA-MB-453 Growth inhibition assay Inhibition of human MDA-MB-453 cell growth in a cell viability assay, IC50 = 22.2184 μM. SANGER
PLC-PRF-5 Growth inhibition assay Inhibition of human PLC-PRF-5 cell growth in a cell viability assay, IC50 = 22.8813 μM. SANGER
EFM-19 Growth inhibition assay Inhibition of human EFM-19 cell growth in a cell viability assay, IC50 = 24.2029 μM. SANGER
SK-N-FI Growth inhibition assay Inhibition of human SK-N-FI cell growth in a cell viability assay, IC50 = 25.1429 μM. SANGER
Saos-2 Growth inhibition assay Inhibition of human Saos-2 cell growth in a cell viability assay, IC50 = 26.765 μM. SANGER
KARPAS-45 Growth inhibition assay Inhibition of human KARPAS-45 cell growth in a cell viability assay, IC50 = 27.5648 μM. SANGER
EKVX Growth inhibition assay Inhibition of human EKVX cell growth in a cell viability assay, IC50 = 27.7875 μM. SANGER
KINGS-1 Growth inhibition assay Inhibition of human KINGS-1 cell growth in a cell viability assay, IC50 = 30.879 μM. SANGER
NCI-H2227 Growth inhibition assay Inhibition of human NCI-H2227 cell growth in a cell viability assay, IC50 = 31.2813 μM. SANGER
D-542MG Growth inhibition assay Inhibition of human D-542MG cell growth in a cell viability assay, IC50 = 32.2968 μM. SANGER
D-263MG Growth inhibition assay Inhibition of human D-263MG cell growth in a cell viability assay, IC50 = 33.5726 μM. SANGER
A498 Growth inhibition assay Inhibition of human A498 cell growth in a cell viability assay, IC50 = 38.4491 μM. SANGER
MDA-MB-157 Growth inhibition assay Inhibition of human MDA-MB-157 cell growth in a cell viability assay, IC50 = 38.5533 μM. SANGER
RMG-I Growth inhibition assay Inhibition of human RMG-I cell growth in a cell viability assay, IC50 = 42.9009 μM. SANGER
COLO-792 Growth inhibition assay Inhibition of human COLO-792 cell growth in a cell viability assay, IC50 = 43.2931 μM. SANGER
SK-MEL-24 Growth inhibition assay Inhibition of human SK-MEL-24 cell growth in a cell viability assay, IC50 = 43.4294 μM. SANGER
SNU-475 Growth inhibition assay Inhibition of human SNU-475 cell growth in a cell viability assay, IC50 = 44.5002 μM. SANGER
HuO-3N1 Growth inhibition assay Inhibition of human HuO-3N1 cell growth in a cell viability assay, IC50 = 46.3321 μM. SANGER
LAN-6 Growth inhibition assay Inhibition of human LAN-6 cell growth in a cell viability assay, IC50 = 46.6441 μM. SANGER
NCI-H720 Growth inhibition assay Inhibition of human NCI-H720 cell growth in a cell viability assay, IC50 = 46.7503 μM. SANGER
BB49-HNC Growth inhibition assay Inhibition of human BB49-HNC cell growth in a cell viability assay, IC50 = 47.6209 μM. SANGER
TT Growth inhibition assay Inhibition of human TT cell growth in a cell viability assay, IC50 = 49.8459 μM. SANGER
HT-29 Cytotoxicity assay In vitro cytotoxic activity against colon adenocarcinoma (HT-29) cells assayed by inhibition of [3H]-labeled thymidine incorporation, IC50 = 0.003 μM. 11728191
NCI-H460 Cytotoxicity assay In vitro cytotoxic activity against nonsmall cell lung carcinoma (NCI-H460) cells assayed by inhibition of [3H]-labeled thymidine incorporation, IC50 = 0.0078 μM. 11728191
MES-SA Cytotoxicity assay In vitro cytotoxic activity against uterine sarcoma (MES-SA) cells assayed by inhibition of [3H]-labeled thymidine incorporation, IC50 = 0.0092 μM. 11728191
DU-145 Cytotoxicity assay In vitro cytotoxic activity against prostate carcinoma (DU-145) cells assayed by inhibition of [3H]-labeled thymidine incorporation, IC50 = 0.0356 μM. 11728191
HepG2 Function assay Activity of human dCK expressed in HepG2 cells assessed as phosphorylation by coupled enzyme assay, Km = 1.4 μM. 17101674
A2780 Growth inhibition assay Growth inhibition of A2780 cells by SRB assay, IC50 = 0.0015 μM. 17602464
H460 Growth inhibition assay Growth inhibition of H460 cells by SRB assay, IC50 = 0.01 μM. 17602464
H292 Growth inhibition assay Growth inhibition of H292 cells by SRB assay, IC50 = 0.013 μM. 17602464
A549 Growth inhibition assay Growth inhibition of A549 cells by SRB assay, IC50 = 0.014 μM. 17602464
A2780 Growth inhibition assay Growth inhibition of A2780 cells by SRB assay in presence of dipyridamole, IC50 = 0.015 μM. 17602464
SW1573 Growth inhibition assay Growth inhibition of SW1573 cells by SRB assay, IC50 = 0.016 μM. 17602464
H460 Growth inhibition assay Growth inhibition of H460 cells by SRB assay in presence of dipyridamole, IC50 = 0.103 μM. 17602464
CEM Growth inhibition assay Growth inhibition of CEM cells by SRB assay, IC50 = 0.13 μM. 17602464
H292 Growth inhibition assay Growth inhibition of H292 cells by SRB assay in presence of dipyridamole, IC50 = 0.21 μM. 17602464
A549 Growth inhibition assay Growth inhibition of A549 cells by SRB assay in presence of dipyridamole, IC50 = 0.225 μM. 17602464
SW1573 Growth inhibition assay Growth inhibition of SW1573 cells by SRB assay in presence of dipyridamole, IC50 = 0.275 μM. 17602464
CEM Growth inhibition assay Growth inhibition of CEM cells by SRB assay in presence of dipyridamole, IC50 = 1 μM. 17602464
AG6000 Growth inhibition assay Growth inhibition of AG6000 cells by SRB assay, IC50 = 20 μM. 17602464
AG6000 Growth inhibition assay Growth inhibition of AG6000 cells by SRB assay in presence of dipyridamole, IC50 = 20 μM. 17602464
DU145 Antiproliferative assay Antiproliferative activity against human DU145 cells by MTT assay, IC50 = 0.0035 μM. 17887663
MDA-MB-231 Antiproliferative assay Antiproliferative activity against human MDA-MB-231 cells by MTT assay, IC50 = 0.0114 μM. 17887663
HCT15 Cytotoxicity assay Cytotoxicity against multidrug-resistant human HCT15 cells by thymidine incorporation assay, IC50 = 11.8 μM. 18186604
HCT116 Cytotoxicity assay Cytotoxicity against multidrug-resistant human HCT116 cells by thymidine incorporation assay, IC50 = 14.3 μM. 18186604
HCT116 Cytotoxicity assay Cytotoxicity against human HCT116 cells by sulforhodamine B method, IC50 = 0.005 μM. 19691349
PC3 Cytotoxicity assay Cytotoxicity against human PC3 cells by sulforhodamine B method, IC50 = 0.04 μM. 19691349
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by sulforhodamine B method, IC50 = 0.09 μM. 19691349
HuH7 Cytotoxicity assay Cytotoxicity against human HuH7 cells by MTS assay, CC50 = 0.1 μM. 20580554
Colo-357 Cytotoxicity assay Cytotoxicity against human Colo-357 cells by crystal violet staining, IC50 = 0.00036 μM. 20930123
PANC1 Cytotoxicity assay Cytotoxicity against human PANC1 cells by crystal violet staining, IC50 = 0.001 μM. 20930123
T3M4 Cytotoxicity assay Cytotoxicity against human T3M4 cells by crystal violet staining, IC50 = 0.0015 μM. 20930123
Patu-T Cytotoxicity assay Cytotoxicity against human Patu-T cells by crystal violet staining, IC50 = 0.0028 μM. 20930123
Patu-S Cytotoxicity assay Cytotoxicity against human Patu-S cells by crystal violet staining, IC50 = 0.0032 μM. 20930123
Patu-02 Cytotoxicity assay Cytotoxicity against human Patu-02 cells by crystal violet staining, IC50 = 0.0034 μM. 20930123
DAN-G Cytotoxicity assay Cytotoxicity against human DAN-G cells by crystal violet staining, IC50 = 0.0034 μM. 20930123
Aspc-1 Cytotoxicity assay Cytotoxicity against human Aspc-1 cells by crystal violet staining, IC50 = 0.004 μM. 20930123
SW1990 Cytotoxicity assay Cytotoxic activity against human SW1990 cells, IC50 = 1.6 μM. 24195466
RT112 Cytotoxicity assay Cytotoxicity against human RT112 cells assessed as cell viability by MTT assay in absence of dCK substrate deoxycytidine, EC50 = 0.0014 μM. 24471998
RT112 Cytotoxicity assay Cytotoxicity against human RT112 cells assessed as cell viability by MTT assay in presence of dCK substrate deoxycytidine, EC50 = 0.1049 μM. 24471998
SW1990 Cytotoxicity assay Cytotoxicity against human SW1990 cells assessed as reduction in cell viability, IC50 = 2.2 μM. 25105722
MDA-MB-231 Antiproliferative assay Antiproliferative activity against human MDA-MB-231 cells, GI50 = 0.000251 μM. 29301085
SW620 Antiproliferative assay Antiproliferative activity against human SW620 cells, GI50 = 0.00084 μM. 29301085
H460 Antiproliferative assay Antiproliferative activity against human H460 cells harboring dominant negative p53 construct, GI50 = 0.002085 μM. 29301085
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生物活性

产品描述 Gemcitabine是核酸合成抑制剂,是有效、特异的脱氧胞苷类似物,用于化疗。Gemcitabine可诱导有效的p53依赖的凋亡。
体外研究(In Vitro)
体外研究活性

在CCRF-CEM人白血病细胞培养物中,Gemcitabine抑制50%的细胞生长,IC50为1 纳克/毫升。Gemcitabine和deoxycytidine联用使生物活性降低1000倍。[1]

在人胰腺癌L3.6pl细胞中,Gemcitabine和C225联用产生额外的细胞毒作用,并随Gemcitabine浓度增多而增强。[2]

在野生型A2780和耐顺铂ADDP细胞中,Gemcitabine和Cisplatin联用产生协同效应。 [3]

实验图片 检测方法 检测指标 实验图片 PMID
Western blot PARP / Cleaved PARP / Cleaved caspase-3 / phopho-p38 / p38 / p-JNK / JNK / p-c-Jun p70S6K1 / p-S6 / HIF-1α 24409315
Immunofluorescence Bim1 27177084
Growth inhibition assay Cell viability 27765914
体内研究(In Vivo)
体内研究活性

在胰腺L3.6pl肿瘤转移的裸鼠中,Gemcitabine和C225联用导致生长抑制,肿瘤消退。Gemcitabine单独给药治疗减少了平均肿瘤体积,从538到152毫米。在Gemcitabine治疗的肿瘤中,Gemcitabine可以减少血管内皮生长因子和白细胞介素8的产生。[2]

Gemcitabine是能够显著地和特异地减少骨髓抑制性细胞的数量,并不显著改变CD4(+)T细胞,CD8(+)T细胞,NK细胞,巨噬细胞,或B细胞的数量。[4]

Gemcitabine和curcumin联用显著减少肿瘤体积(与对照组和单独Gemcitabine处理相比),Ki-67的增殖指数(与对照组相比),NF-κB的激活和表达NF-κB的调节基因产物(细胞周期蛋白D1,c-myc的和Bcl-2和Bcl-xL的细胞凋亡蛋白-1,环氧化酶-2,基质金属蛋白酶,和血管内皮生长因子的细胞抑制剂)。Gemcitabine和curcumin联用也抑制血管生成,以CD31(+)的微血管密度为标志。[5]

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06320301 Recruiting
Biliary Tract Cancer|Gemox Chemotherapy
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University|Suzhou Suncadia Biopharmaceuticals Co. Ltd.
April 1 2024 Phase 2
NCT06046794 Not yet recruiting
Cancer Of Pancreas
Institut Paoli-Calmettes
February 1 2024 Not Applicable
NCT06199466 Recruiting
Metastatic Pancreatic Cancer
M.D. Anderson Cancer Center|280Bio Inc
January 22 2024 Phase 1
NCT06055348 Not yet recruiting
Serous Ovarian Cancer|Advanced Ovarian Cancer
Biocity Biopharmaceutics Co. Ltd.
October 30 2023 Phase 1|Phase 2

化学信息&溶解度

分子量 263.2 分子式

C9H11F2N3O4

CAS号 95058-81-4 SDF Download Gemcitabine SDF
Smiles C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F
储存条件(自收到货起) 4℃保存(避光)

体外溶解度
批次:

DMSO : 53 mg/mL ( (201.36 mM) ;DMSO吸湿会降低化合物溶解度,请使用新开封DMSO)

Water : Insoluble

Ethanol : Insoluble

摩尔浓度计算器

体内溶解度
批次:

现配现用,请按从左到右的顺序依次添加,澄清后再加入下一溶剂

动物体内配方计算器

实验计算

摩尔浓度计算器

质量 浓度 体积 分子量

动物体内配方计算器(澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)

mg/kg g μL

第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系Selleck为您提供正确的澄清溶液配方)

% DMSO % % Tween 80 % ddH2O
%DMSO %

计算结果:

工作液浓度: mg/ml;

DMSO母液配制方法: mg 药物溶于μL DMSO溶液(母液浓度mg/mL,:如该浓度超过该批次药物DMSO溶解度,请先联系Selleck);

体内配方配制方法:μL DMSO母液,加入μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入μL ddH2O,混匀澄清。

体内配方配制方法:μL DMSO母液,加入μL Corn oil,混匀澄清。

注意:1. 首先保证母液是澄清的;
2.一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。

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常见问题及建议解决方法

问题 1:
What is the difference between gemcitabine(S1714 ) and Gemcitabine HCl (S1149)?

回答:
Gemcitabine HCl is the HCl salt form of Gemcitabine. They have the same biological activities. The free base(S1714) dissolves better in DMSO, and the hydrochloride (S1149) dissolves better in water.

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