Fluorouracil (5-Fluorouracil, 5-FU)

For research use only. Not for use in humans.

目录号:S1209 别名: NSC 19893 中文名称:氟尿嘧啶

Fluorouracil (5-Fluorouracil, 5-FU) Chemical Structure

CAS No. 51-21-8

Fluorouracil (5-Fluorouracil, 5-FU, NSC 19893) 是DNA/RNA合成抑制剂,在肿瘤细胞中通过抑制胸苷酸合成酶(TS)而干扰核苷酸合成。Fluorouracil 可诱导细胞凋亡并可用于治疗HIV。

规格 价格 库存 购买数量  
10mM (1mL in DMSO) RMB 1091.79 现货
RMB 1187.43 现货
RMB 1799.08 现货
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客户使用Selleck生产的Fluorouracil (5-Fluorouracil, 5-FU)发表文献132篇:

产品安全说明书

DNA/RNA Synthesis抑制剂选择性比较

生物活性

产品描述 Fluorouracil (5-Fluorouracil, 5-FU, NSC 19893) 是DNA/RNA合成抑制剂,在肿瘤细胞中通过抑制胸苷酸合成酶(TS)而干扰核苷酸合成。Fluorouracil 可诱导细胞凋亡并可用于治疗HIV。
靶点
Thymidylate synthase [1]
(Tumor cells)
体外研究

Adrucil是一种尿嘧啶类似物,在C-5位置上有一个氟原子。利用和尿嘧啶一致的转运途径快速进入细胞。Adrucil在细胞内转化成几个活性代谢物:氟脱氧尿苷单磷酸盐(FdUMP),氟脱氧尿苷三磷酸盐(FdUTP) 以及氟尿苷三磷酸盐 (FUTP)。Adrucil的代谢物FdUMP结合到TS核苷酸结合位点,与CH2THF形成稳定的三聚体,进而阻断了正常的底物dUMP的结合,抑制了dTMP的合成。Adrucil代谢物能够插入DNA,导致DNA双链断裂和细胞死亡。Adrucil的促凋亡作用可能和激活肿瘤抑制因子P53有关。P53功能缺失降低细胞对Adrucil的敏感性。[1]Adrucil抑制存活诱导各种细胞的凋亡。Adrucil 抑制鼻咽癌细胞系CNE2 和 HONE的生存能力[2],Adrucil抑制Capan-1细胞的生存能力[3],Adrucil抑制HT-29细胞的生存能力[4],IC50 分别是 9 μg/mL, 3 μg/mL, 0.22 μM, 2.5 μM。

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H292 NUjKT4dNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{XWR|czyqCqwrC= NFnoOJRKSzVyPjCyOUDPxGdxbVy= NYPuVHVbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwPVUyPzZpPkK0NFk2OTd4PD;hQi=>
HL-60 MnzTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnfoO|LDqGkEoB?= NWLKSVlLUUN3ME24MlYxOSEQvHevcWw> Mn3ZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyOUWxO|YoRjJ2MEm1NVc3RC:jPh?=
HT-29 NGjHVVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3nvflczyqCqwrC= M2LqWGlEPTB-IEK1JO69\y:vTB?= NYXuUZhIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwPVUyPzZpPkK0NFk2OTd4PD;hQi=>
MCF-7 MmXjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUG3NuKhcMLi M{m2S2lEPTB;MkCg{txoN22O NG[0XVE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEC5OVE4Pid-MkSwPVUyPzZ:L3G+
L1210/0 MWDGeY5kfGmxbjDhd5NigQ>? NH\Lb3lG\m[nY4Sgc44hVDF{MUCvNEBk\WyuczDpckBkfWy2dYLlMEBKSzVyIE2gNE4{KM7:TT6= M3;SOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NkKyO|goRjJ|NkKyO|g9N2F-
CCRF-CEM M4i4fmZ2dmO2aX;uJIF{e2G7 NGG1bpdG\m[nY4Sgc44hS0OURj3DSW0h[2WubIOgbY4h[3WudIXy[UwhUUN3MDC9JFIh|ryPLh?= MofHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4MkK3PEc,OjN4MkK3PFww[T5?
P388 MXLBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NIDOXYw1QCCqcoO= NV7HV|BDSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBud3W|ZTDQN|g5KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlYxQSEQvF2u NVvOeoZiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke3PFQ1QSd-Mke3PFQ1QTxxYU6=
HT-29 NEntPZBCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MX25OkBpenN? MUDBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEiWLUK5JINmdGy|IHHmeIVzKDl4IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSByLk[5JO69VS5? M4HXPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5N{i0OFkoRjJ5N{i0OFk9N2F-
L1210 NHvM[3dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NED1Z3hKdmirYnn0bY9vKG:oIHPlcIwh\3Kxd4ToJI9nKExzMkGwJI1wfXOnIFzleYtmdWmjIHPlcIx{NCCLQ{WwJF0hOC5|IN88UU4> Mn3jQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl4N{O3OUc,Ojl4N{O3OVww[T5?
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CCRF-CEM NEDISXFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1rlZWNwdmOnboTyZZRqd25icnXxeYlz\WRiZn;yJJRp\SB3MDWgbY5pcWKrdHnvckBw\iCpcn;3eIghd2ZiQ1PSSk1ETU1iaIXtZY4hdGW3a3XtbYEh[2WubIOgbY4h[3WudIXy[UwhUUN3MDC9JFUh|ryPLh?= NWHPXpBQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxN{GyNFI6OCd-N{GyNFI6ODxxYU6=
L1210 NHXWNZpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXToS29wPDhiaILz NVn2U|JFUW5idnn0do8h\3Kxd4ToJIlvcGmkaYTpc44hd2ZiTEGyNVAh[2WubIOgOFghcG:3coOgZYZ1\XJiYXTtbY5qe3S{YYTpc44hd2ZiY3;tdI92dmRuIFnDOVAhRSByLkGyJO69VS5? NGPIdJY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi95NkK5PFA3Lz55NkK5PFA3RC:jPh?=
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L1210 NYTM[VFHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlrNNkBpenN? NHPPS49KdiC4aYTyc{Boem:5dHigbY5pcWKrdHnvckBw\iCOMUKxNEBk\WyuczCyJIhwfXK|IHHmeIVzKGGmbXnubZN1emG2aX;uJI9nKGOxbYDveY5lNCCLQ{WwJF0hOi5{IN88UU4> M1O4WFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzd4Mkm4NFYoRjd4Mkm4NFY9N2F-
CHO NX3jbGYxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYLHdo94fGhiaX7obYJqfG:{eTDhZ5Rqfmm2eTDh[4FqdnO2IFPIU{Bk\WyuczDpckBkfWy2dYLlMkwhUUN3MDC9JFUh|ryPLh?= NXTzXJdwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxN{i1N|M1Oid-N{i1N|M1OjxxYU6=
SCLC NHj6PYJEgXSxdH;4bYNqfHliYYPzZZk> NFf6R4xEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUS0yFIHPlcIx{KHKnc3nzeIFvfCC2bzDjbZNxdGG2aX6gLHNEVENxQ1TEVEktKEmFNUCgQUA5NjRizszNMi=> NVjTWVV[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxOEK1PFg{PSd-OEK1PFg{PTxxYU6=
T-24 M2\XT2N6fG:2b4jpZ4l1gSCjc4PhfS=> NWi4OpZUXGW|dHXkJIZweiCleYTveI95cWOrdImgZYdicW6|dDDhcpRq\2WwIH7l[4F1cX[nIGStNlQh[myjZHTldkBk[XKlaX7vcYEh[2WubIOgbIF3cW6pIH;ucJkhOy13JTDhcpRq\2WwIHX4dJJme3Orb36sJGlEPTBiPTC0MlEh|ryPLh?= MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek85PDl4OUK2K|45PDl4OUK2QE9iRg>?
791T M{G1[GN6fG:2b4jpZ4l1gSCjc4PhfS=> MnKxWIV{fGWmIH\vdkBkgXSxdH;4bYNqfHliYXfhbY5{fCCjboTp[4VvKHCxc3n0bZZmKDd7MWSgc5N1\W:|YYLjc41iKGOnbHzzJIhifmmwZzDvcox6KDNvNTWgZY51cWenbjDlfJBz\XO|aX;uMEBKSzVyIE2gOU42KM7:TT6= M3TIe|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzh2OU[5NlYoRjh2OU[5NlY9N2F-
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SK-MEL-28 MYrBcpRq[2GwY3XyJIF{e2G7 NHm5eXNV\XO2ZXSgbY4hfmm2cn:g[o9zKGGwdHnjZY5k\XJiYXP0bZZqfHliYXfhbY5{fCCVSz3NSWwuOjhiY3XscJMtKEmFNUCgQUA1NjVizszNMi=> MmjxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTByN{K2PFMoRjFyMEeyOlg{RC:jPh?=
PBM NV[zSZJSS3m2b4TvfIlkcXS7IHHzd4F6 M1jjUHRme3SnZDDpckB3cXS{bzDmc5Ih[3m2b4TvfIlkcXS7IHHnZYlve3RiUFLNJINmdGy|LDDJR|UxKD1iNTFOwG0v NX60dolNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUCwO|I3QDNpPkGwNFczPjh|PD;hQi=>
Vero MofGR5l1d3SxeHnjbZR6KGG|c3H5 MXnU[ZN1\WRiaX6geol1em9iZn;yJIN6fG:2b4jpZ4l1gSCjZ3HpcpN1KF[ncn:gZ4VtdHNuIFnDOVAhRSB4LkixJO69VS5? M2i2[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFyMEeyOlg{Lz5zMEC3NlY5OzxxYU6=
SK-MES-1 MULBcpRq[2GwY3XyJIF{e2G7 NVXyVZd{XGW|dHXkJIlvKH[rdILvJIZweiCjboTpZ4Fv[2W{IHHjeIl3cXS7IHHnZYlve3RiU1utUWVUNTFiY3XscJMtKEmFNUCgQUAyOy5zIN88UU4> NI[3OmM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMEC3NlY5Oyd-MUCwO|I3QDN:L3G+
HepG2 MWrBcpRq[2GwY3XyJIF{e2G7 Ml7BWIV{fGWmIHnuJJZqfHKxIH\vdkBidnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhUGWyR{KgZ4VtdHNuIFnDOVAhRSB|Nz65JO69VS5? M2\1WFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFyMEeyOlg{Lz5zMEC3NlY5OzxxYU6=
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SW480 M1TyVmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M3HEWVczKGi{cx?= NYHjNWdMSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTW|Q5OCClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKG2ndHjv[EwhUUN3MDC9JFgvOSEQvF2u M1rOclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUK0OlU2Lz5zN{WyOFY2PTxxYU6=
MDA-MB-435S MorPRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MVO3NkBpenN? NFriToxCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3ERU1OSi12M{XTJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgcYV1cG:mLDDJR|UxKD1iMUSuOUDPxE1w MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzV{NE[1OUc,OTd3MkS2OVU9N2F-
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A549 M37iZmN6fG:2b4jpZ4l1gSCjc4PhfS=> M2ns[lQ5KGi{cx?= MWjDfZRwfG:6aXPpeJkh[WejaX7zeEBCPTR7IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA6NjJizszNMi=> NXfGT2tLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2NFQ{QTRpPkG3OlA1Ozl2PD;hQi=>
L1210 M1\uZmN6fG:|dHH0bYMh[WO2aY\peJkh[XO|YYm= M2jkV2N6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBud3W|ZTDMNVIyOCClZXzsd{whUUN3MDC9JFAvOjhizszNMi=> NXz3SGp3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe5N|E5PjJpPkG3PVMyQDZ{PD;hQi=>
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HepG2 M1HKOWN6fG:2b4jpZ4l1gSCjc4PhfS=> MYrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{whUUN3MDC9JFE5NjdizszNMi=> MmLxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh|MEKzN|YoRjF6M{CyN|M3RC:jPh?=
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Hep2 MUjBcpRq[2GwY3XyJIF{e2G7 MVu0PEBpenN? M33YN2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[ZAzKGOnbHzzJIF{e2W|c3XkJIF{KGOnbHygeoli[mmuaYT5JIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGlEPTBiPTCwMlMh|ryPLh?= MlS0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFyN{S0OFQoRjJzMEe0OFQ1RC:jPh?=
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CEM M{\6XWN6fG:|dHH0bYMh[WO2aY\peJkh[XO|YYm= MoPxR5l1d3O2YYTpZ{Bi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFPFUUBk\WyuczygTWM2OCB;IEG4JO69VS5? MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTlzN{O2N{c,OjF7MUezOlM9N2F-
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HepG2 NXHadWt4S3m2b4TvfIlkcXS7IHHzd4F6 MWmzJIRigXN? MWfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjCzJIRigXNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNk44KM7:TT6= NVrMe|Y4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKwNFA6OjVpPkKyNFAxQTJ3PD;hQi=>
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colon cancer cell NVW5TVdlS3m2b4TvfIlkcXS7IHHzd4F6 Mk[zOFghcHK| MofLR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gZ49td25iY3HuZ4VzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDjc5VtfGW{IHPveY51cW6pLDDHTVUxKD1iOD60JO69VS5? MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjB3NkK3O{c,OjJyNU[yO|c9N2F-
leukemia cell Mk\YR5l1d3SxeHnjbZR6KGG|c3H5 MVi0PEBpenN? MlTJR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gcIV2c2WvaXGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KGOxdXz0[ZIh[2:3boTpcoctKEeLNUCgQUAyPS5zIN88UU4> Mn:1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJyNU[yO|coRjJ{MEW2Nlc4RC:jPh?=
prostate cancer cell NV20XJFmS3m2b4TvfIlkcXS7IHHzd4F6 Mn[0OFghcHK| NXPmUVJXS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4heHKxc4TheIUh[2GwY3XyJINmdGy|IHHmeIVzKDR6IHjyd{BjgSClb4XseIVzKGOxdX70bY5oNCCJSUWwJF0hOjJwNzFOwG0v Ml64QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJyNU[yO|coRjJ{MEW2Nlc4RC:jPh?=
renal cancer cell MXfDfZRwfG:6aXPpeJkh[XO|YYm= M13XcFQ5KGi{cx?= NF;GRW1EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBz\W6jbDDjZY5k\XJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JINwfWy2ZYKgZ492dnSrbnesJGdKPTBiPTC0OU43KM7:TT6= NEGyNoI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkC1OlI4Pyd-MkKwOVYzPzd:L3G+
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GLC82 NIn3R3ZCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M4\QNVczKGi{cx?= MX\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEeOQ{iyJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzNT61JO69VS5? M{\HTVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MEe5N|c5Lz5{MkC3PVM4QDxxYU6=
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CNE2 MVHBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NFTIeVk4OiCqcoO= MX\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEOQRUKgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF5LkKg{txONg>? MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjB5OUO3PEc,OjJyN{mzO|g9N2F-
HEK293 NH\UNJVEgXSxdH;4bYNqfHliYYPzZZk> NHvQdYczKGSjeYO= NELMNnpEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJTUt{OUOgZ4VtdHNiYX\0[ZIhOiCmYYnzJIJ6KGGuYX3hdkBjdHWnIHHzd4F6NCCLQ{WwJF0hPDJwOTFOwG0v NXjsV3FpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKwPVM4PjFpPkKyNFk{PzZzPD;hQi=>
colon cancer cell NGjyRoNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEn4V|Y1QCCqcoO= NIDUOGFIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBkd2yxbjDjZY5k\XJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JINwfWy2ZYKgZ492dnSncjDt[ZRpd2RuIFfJOVAhRSB6LkSg{txONg>? M2S2e|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MUG5NVUyLz5{MkGxPVE2OTxxYU6=
leukemia cell NVfWN|JNT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFvBe2M1QCCqcoO= M{n0UWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJIxmfWunbXnhJINmdGy|IHHmeIVzKDR6IHjyd{BjgSClb4XseIVzKGOxdX70[ZIhdWW2aH;kMEBIUTVyIE2gNVUvOSEQvF2u NV7CRmg3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKxNVkyPTFpPkKyNVE6OTVzPD;hQi=>
prostate cancer cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M13JRVQ5KGi{cx?= M2LGbGdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJJBzd3O2YYTlJINidmOncjDj[YxteyCjZoTldkA1QCCqcoOgZpkh[2:3bITldkBkd3WwdHXyJI1mfGixZDygS2k2OCB;IEKyMlch|ryPLh?= MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjFzOUG1NUc,OjJzMUmxOVE9N2F-
renal cancer cell NFjX[GNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnvPOFghcHK| M1HlOmdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJJJmdmGuIHPhcoNmeiClZXzsd{Bi\nSncjC0PEBpenNiYomgZ492dHSncjDjc5VvfGW{IH3leIhw\CxiR1m1NEA:KDR3Lk[g{txONg>? Mm\EQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzMUmxOVEoRjJ{MUG5NVUyRC:jPh?=
H460 M{L1UWN6fG:2b4jpZ4l1gSCjc4PhfS=> NIXKOIE4OiCqcoO= M4TnOGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGg1PjBiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFMh|ryPLh?= M1HUNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MUOwNVMzLz5{MkGzNFE{OjxxYU6=
HCT116 MmPMR5l1d3SxeHnjbZR6KGG|c3H5 NXG4PYNDPzJiaILz NX7QeWlZS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUG2JINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB2IN88UU4> MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjF|MEGzNkc,OjJzM{CxN|I9N2F-
MCF7 MoGzR5l1d3SxeHnjbZR6KGG|c3H5 NFXXVnY4OiCqcoO= MWfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxOEDPxE1w M3nVeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MUOwNVMzLz5{MkGzNFE{OjxxYU6=
A549 MV3DfZRwfG:6aXPpeJkh[XO|YYm= NUPzeZB1OjRiaILz NEnPR|JEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFI1KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA2NjZ2IN88UU4> M2\HbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MUiyPVI3Lz5{MkG4NlkzPjxxYU6=
QGY7701 MYrDfZRwfG:6aXPpeJkh[XO|YYm= NF\YU4kzPCCqcoO= NIDZTGlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBST1l5N{CxJINmdGy|IHHmeIVzKDJ2IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzND6zJO69VS5? NYXvO|J[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKxPFI6OjZpPkKyNVgzQTJ4PD;hQi=>
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CNE2 MXTDfZRwfG:6aXPpeJkh[XO|YYm= NWjnVplDPzJiaILz Mmq0R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR25GOiClZXzsd{Bi\nSncjC3NkBpenNibomgUXRVKGG|c3H5MEBKSzVyIE2gNVMvPSEQvF2u NV;6[Jp3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKyNFA1ODRpPkKyNlAxPDB2PD;hQi=>
HepG2 M4TZV2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 MUK0PEBpenN? NYXOcVB1SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVUvQTJizszNMi=> Mo[4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ{MEm0PFYoRjJ{MkC5OFg3RC:jPh?=
NCI-H460 MkP2R5l1d3SxeHnjbZR6KGG|c3H5 M4H2b2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG5EUS2KNE[wJINmdGy|LDDJR|UxKD1iODFOwG0v NHTNWY89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkK4N|Q2OSd-MkKyPFM1PTF:L3G+
SMMC7721 NXjsS4l6S3m2b4TvfIlkcXS7IHHzd4F6 M2DFZ2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNOVUN5N{KxJINmdGy|LDDJR|UxKD1iMUWg{txONg>? MlHPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ{OEO0OVEoRjJ{MkizOFUyRC:jPh?=
MCF7 M2rJ[GN6fG:2b4jpZ4l1gSCjc4PhfS=> M1XueGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMtKEmFNUCgQUA{OSEQvF2u MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjJ6M{S1NUc,OjJ{OEO0OVE9N2F-
NCI-H460 M1znbmN6fG:2b4jpZ4l1gSCjc4PhfS=> M13ad|Q5KGi{cx?= NGPGSYxEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBPS0lvSES2NEBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMkmg{txONg>? MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjNyNEO0OEc,OjJ|MESzOFQ9N2F-
B16 NUXWZ205S3m2b4TvfIlkcXS7IHHzd4F6 M1rueFQ5KGi{cx?= MUfDfZRwfG:6aXPpeJkh[WejaX7zeEBud3W|ZTDCNVYh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEOzJO69VS5? NGHB[Xg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkOwOFM1PCd-MkKzNFQ{PDR:L3G+
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HepG2 NHjodFdEgXSxdH;4bYNqfHliYYPzZZk> MVe3NkBpenN? MWPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|IvOjJizszNMi=> M3;GSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{Nki3O|Q2Lz5{Mk[4O|c1PTxxYU6=
NCI-H460 M4\uXWN6fG:2b4jpZ4l1gSCjc4PhfS=> MmKyO|IhcHK| NGT5NHVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBPS0lvSES2NEBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMj60JO69VS5? MlK1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ5Mke0OFUoRjJ{N{K3OFQ2RC:jPh?=
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HepG2 M{TBSmN6fG:2b4jpZ4l1gSCjc4PhfS=> MYe3NkBpenN? MoXOR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQvQCEQvF2u MnTTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ5Mke0OFUoRjJ{N{K3OFQ2RC:jPh?=
SGC7901 MlHzR5l1d3SxeHnjbZR6KGG|c3H5 MVq3NkBpenN? MVXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTS2M4QTBzIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA3NjNizszNMi=> NGK2XHM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkeyO|Q1PSd-MkK3Nlc1PDV:L3G+
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MGC803 NEXNellEgXSxdH;4bYNqfHliYYPzZZk> NIXQdGQ4OiCqcoO= M2\0PGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ISzhyMzDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOThwNTFOwG0v NUXlclh1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK3OFkyQTJpPkKyO|Q6OTl{PD;hQi=>
MCF7 NE\xUpVCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NYjxTINQPzJiaILz Ml\PRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPQ1[3JINmdGy|IHHmeIVzKDd{IHjyd{BjgSClconzeIFtKH[rb3zleEB{fGGrbnnu[{Bu\XSqb3SsJGlEPTBiPTC0Mlch|ryPLh?= NF\EVWM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mke2OVg6Pyd-MkK3OlU5QTd:L3G+
HT-29 M3vGSmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NXvB[2VRPzJiaILz NGK2VnBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjUMVI6KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDjdpl{fGGuII\pc4xmfCC|dHHpcolv\yCvZYToc4QtKEmFNUCgQUA4NjNizszNMi=> NHzxSW89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mke2OVg6Pyd-MkK3OlU5QTd:L3G+
MDA-MB-231 NYTVNWRxSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NHnHOFA4OiCqcoO= NU\NW5E{SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvMkOxJINmdGy|IHHmeIVzKDd{IHjyd{BjgSClconzeIFtKH[rb3zleEB{fGGrbnnu[{Bu\XSqb3SsJGlEPTBiPTC5MlYh|ryPLh?= M2m2fVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{N{[1PFk4Lz5{Mke2OVg6PzxxYU6=
HT1080 MY\DfZRwfG:6aXPpeJkh[XO|YYm= NV\NRYFCS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUFRzMEiwJINmdGy|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFMvODZizszNMi=> MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjhyMU[0OEc,OjJ6MEG2OFQ9N2F-
A375-S2 MoLLR5l1d3SxeHnjbZR6KGG|c3H5 MV\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBN|c2NVN{IHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OCB;IEmuPVIh|ryPLh?= NYPNRndvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4NFE3PDRpPkKyPFAyPjR2PD;hQi=>
HeLa NIDSfXlEgXSxdH;4bYNqfHliYYPzZZk> MnTyR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzMD6zOkDPxE1w MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjhyMU[0OEc,OjJ6MEG2OFQ9N2F-
HepG2 Mn\LR5l1d3SxeHnjbZR6KGG|c3H5 NUHPTYV2S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVAvPDVizszNMi=> M1LuZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OECxOlQ1Lz5{MkiwNVY1PDxxYU6=
BGC823 MVfDfZRwfG:6aXPpeJkh[XO|YYm= NY\nfXNHS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSkeFOEKzJINmdGy|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE2NjZ3IN88UU4> NWLUSI9CRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4NFE3PDRpPkKyPFAyPjR2PD;hQi=>
Hep2 MV;DfZRwfG:6aXPpeJkh[XO|YYm= MnjCR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxOiClZXzsd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{ND61PEDPxE1w Ml\5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6MEG2OFQoRjJ{OECxOlQ1RC:jPh?=
MCF7 NULKeGc5S3m2b4TvfIlkcXS7IHHzd4F6 NGnZPGNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OCB;IEK0MlU5KM7:TT6= M{DkTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OECxOlQ1Lz5{MkiwNVY1PDxxYU6=
A549 NYTaZowxS3m2b4TvfIlkcXS7IHHzd4F6 M1\3b2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[nliTWTUJIF{e2G7LDDJR|UxKD1iM{GuOVIh|ryPLh?= MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjhyMU[0OEc,OjJ6MEG2OFQ9N2F-
MDA231 MYHDfZRwfG:6aXPpeJkh[XO|YYm= M1fmRWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSTJ|MTDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzNU42PyEQvF2u MnrIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6MEG2OFQoRjJ{OECxOlQ1RC:jPh?=
PC3 MnHGR5l1d3SxeHnjbZR6KGG|c3H5 NGjQc2dEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSzNiY3XscJMh[nliTWTUJIF{e2G7LDDJR|UxKD1iM{WuO|Uh|ryPLh?= NHGweXQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkiwNVY1PCd-MkK4NFE3PDR:L3G+
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MKN45 M1fFdmN6fG:2b4jpZ4l1gSCjc4PhfS=> NYT1bIZmPDhiaILz M{HQNWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1MVjR3IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1OS55MzFOwG0v M2rs[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OEC5OVU5Lz5{MkiwPVU2QDxxYU6=
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A549 MoqyRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MmLIOFghcHK| NVvteo1{SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNk45KM7:TT6= MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjh2MES5N{c,OjJ6NEC0PVM9N2F-
MCF7 MWPBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NWPibI41PDhiaILz NVLrXZRsSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxOk4zKM7:TT6= M2La[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OESwOFk{Lz5{Mki0NFQ6OzxxYU6=
IOSE-144 NXjCWWh7SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= M17PSVQ5KGi{cx?= Mn7VRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCLT2PFMVE1PCClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlUvPiEQvF2u M2LmdVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OESwOFk{Lz5{Mki0NFQ6OzxxYU6=
CAMA1 MkK5R5l1d3SxeHnjbZR6KGG|c3H5 MYe3NkBpenN? MWjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDRW1COSClZXzsd{BqdmO3YnH0[YQh\m:{IEeyJIhzeyCkeTDTVmIh[XO|YYmsJGlEPTBiPTCxMlI5KM7:TT6= MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjh4N{ewO{c,OjJ6Nke3NFc9N2F-
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HCT15 Mk\tR5l1d3SxeHnjbZR6KGG|c3H5 NUewZoluOjRiaILz NImzSI5EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1RzNTDj[YxteyCjZoTldkAzPCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPDVwMEGg{txONg>? NEXuRm89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{KwNlQ5PCd-MkOyNFI1QDR:L3G+
MCF7 MWLDfZRwfG:6aXPpeJkh[XO|YYm= M37Wc|czKGi{cx?= MYrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxO{4zKM7:TT6= MmDCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN{N{m4OlQoRjJ|Mke5PFY1RC:jPh?=
HepG2 Mlm0R5l1d3SxeHnjbZR6KGG|c3H5 MmHhO|IhcHK| M3\ZNWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzOS57IN88UU4> Ml;hQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN{N{m4OlQoRjJ|Mke5PFY1RC:jPh?=
SGC7901 NYnXdJpFS3m2b4TvfIlkcXS7IHHzd4F6 MkjGO|IhcHK| M4nWS2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNISzd7MEGgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ6LkWg{txONg>? Mnu5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN{N{m4OlQoRjJ|Mke5PFY1RC:jPh?=
HCT116 M{\0emFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MVi0PEBpenN? M1;RUmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFPUNVE3KGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25iY3XscEBxem:uaX\ldoF1cW:wIHHmeIVzKDR6IHjyd{BjgSCVdXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBKSzVyIE2gN{42PiEQvF2u NHTDU2s9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{OwOVkyQSd-MkOzNFU6OTl:L3G+
B16F10 MnfYRY51cWOjbnPldkBie3OjeR?= NXLOXZBpPDhiaILz M1TSWmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBud3W|ZTDCNVZHOTBiY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB{fXK4aY\hcEBu\WG|dYLl[EBi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlEvPDFizszNMi=> NF6xXHQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{OxNlk1QSd-MkOzNVI6PDl:L3G+
SGC7901 Ml[3RY51cWOjbnPldkBie3OjeR?= MkC5OFghcHK| NEHEdYZCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV2dEPzlyMTDj[YxteyCjc4Pld5Nm\CCjczDj[YxtKHO3co\peoFtKG2nYYP1doVlKGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1Pi5|NTFOwG0v M2\TflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|M{GyPVQ6Lz5{M{OxNlk1QTxxYU6=
HeLa NIDrU29CdnSrdIXtc5Ih[XO|YYm= M3LP[FQ5KGi{cx?= NX\zbXFuSW62aYT1cY9zKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bie3Onc4Pl[EBieyCpcn;3eIghcW6qaXLpeIlwdiCvZXHzeZJm\CCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTRwN{ig{txONg>? NYfkRmU2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOzNVM3OzVpPkKzN|E{PjN3PD;hQi=>
A549 M2jkXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mor0OFghcHK| NYLJZ|g3T3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPS54NDFOwG0v MlLiQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN|NUO3N|coRjJ|M{WzO|M4RC:jPh?=
QGY7701 M3fLd2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2WzR|Q5KGi{cx?= Ml\YS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gVWd[PzdyMTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTRwMzFOwG0v NX7zTZRnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOzOVM4OzdpPkKzN|U{PzN5PD;hQi=>
HuH7 MlPtS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUDFXFVbPDhiaILz Mo\qS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gTJVJPyClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVUvQDVizszNMi=> MmrRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN|NUO3N|coRjJ|M{WzO|M4RC:jPh?=
HeLa MlyzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFf2elQ1QCCqcoO= Mn36S5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVYvOzJizszNMi=> MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzN3M{ezO{c,OjN|NUO3N|c9N2F-
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EC109 M{nDSmN6fG:2b4jpZ4l1gSCjc4PhfS=> NID6dGU4OiCqcoO= MWfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDFR|ExQSClZXzsd{Bie3Onc4Pl[EBieyCpcn;3eIghcW6qaXLpeIlwdiCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOy5|NDFOwG0v MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzN3M{e0N{c,OjN|NUO3OFM9N2F-
MGC803 Ml7oR5l1d3SxeHnjbZR6KGG|c3H5 NUPHdHo1PzJiaILz MUnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNS2M5ODNiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDdwMEGg{txONg>? M3y0XlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|M{WzO|Q{Lz5{M{O1N|c1OzxxYU6=
MCF7 M17MV2N6fG:2b4jpZ4l1gSCjc4PhfS=> MV:3NkBpenN? NHf4OXZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGG|c3Xzd4VlKGG|IHfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB5LkW0JO69VS5? NWfjeGFJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOzOVM4PDNpPkKzN|U{PzR|PD;hQi=>
PC3 MnPvR5l1d3SxeHnjbZR6KGG|c3H5 MkGxO|IhcHK| NHTKU|BEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSzNiY3XscJMh[XO|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ5LkC3JO69VS5? NEjLd|g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{O1N|c1Oyd-MkOzOVM4PDN:L3G+
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leukemia M1nhb2N6fG:2b4jpZ4l1gSCjc4PhfS=> M4D3eVQ5KGi{cx?= NGXoe4NEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBt\XWtZX3pZUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4XsdIhwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUAyPS5zIN88UU4> NGmyU5M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{S3OFg6QSd-MkO0O|Q5QTl:L3G+
prostate cancer MoTJR5l1d3SxeHnjbZR6KGG|c3H5 NInud2o1QCCqcoO= MnvyR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gdJJwe3SjdHWgZ4Fv[2W{IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyyaH;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IEKyMlch|ryPLh?= MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzR5NEi5PUc,OjN2N{S4PVk9N2F-
renal cancer MnOyR5l1d3SxeHnjbZR6KGG|c3H5 MVS0PEBpenN? NV;xNJl6S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hemWwYXygZ4Fv[2W{IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyyaH;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IES1MlYh|ryPLh?= MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzR5NEi5PUc,OjN2N{S4PVk9N2F-
MCF7 M{HkV2N6fG:2b4jpZ4l1gSCjc4PhfS=> NXjUXXYzPDhiaILz MnnWR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVYvPyEQvF2u M1ywNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NEmwNVU6Lz5{M{S5NFE2QTxxYU6=
HepG2 MXfDfZRwfG:6aXPpeJkh[XO|YYm= NVrQ[XZtPDhiaILz M13Sc2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzOi56IN88UU4> MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzR7MEG1PUc,OjN2OUCxOVk9N2F-
SGC7901 NIjOTGtEgXSxdH;4bYNqfHliYYPzZZk> M{\TdlQ5KGi{cx?= MW\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTS2M4QTBzIHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzQC57IN88UU4> NXjtZ5hbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO0PVAyPTlpPkKzOFkxOTV7PD;hQi=>
THP1 M4rDe2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 MoLCOFghcHK| MXvBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFSKUEGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGlEPTBiPTCxJO69VS5? MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzVyMUGxN{c,OjN3MEGxNVM9N2F-
PC3 M3nVdWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NYftcopLPDhiaILz NFy2U4ZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGDDN{Bk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhUUN3MDC9JFIvOiEQvF2u NUD3b5pmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO1NFEyOTNpPkKzOVAyOTF|PD;hQi=>
Hep2 MnPaRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NVnYSWpIPDhiaILz MVPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEincEKgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGlEPTBiPTC0MlUh|ryPLh?= M3GyO|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NUCxNVE{Lz5{M{WwNVEyOzxxYU6=
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K562 NITxZYREgXSxdH;4bYNqfHliYYPzZZk> MofvO|IhcHK| MoXWR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT|U3OiClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlgh|ryPLh?= NEXOVmU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{WzOVMzOid-MkO1N|U{OjJ:L3G+
CEM M3GzVGN6fG:2b4jpZ4l1gSCjc4PhfS=> M1HvWlczKGi{cx?= NVjoUmRxS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hS0WPIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA{OiEQvF2u NVjPbZRwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO1N|U{OjJpPkKzOVM2OzJ{PD;hQi=>
A375-S2 M4DoUWN6fG:2b4jpZ4l1gSCjc4PhfS=> MX:0PEBpenN? NEHF[XJEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCOzd3LWOyJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB4Lk[3JO69VS5? MnvEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN3NUiyN|goRjJ|NUW4NlM5RC:jPh?=
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MCF7 M4fVRWN6fG:2b4jpZ4l1gSCjc4PhfS=> NF\Scok1QCCqcoO= M{PZc2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFEyNjVizszNMi=> NYL5NZQyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO1OVgzOzhpPkKzOVU5OjN6PD;hQi=>
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HepG2 MYHDfZRwfG:6aXPpeJkh[XO|YYm= NF;LOIM1QCCqcoO= M1;pO2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1OC5|NDFOwG0v NWLQXmFMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO1OVgzOzhpPkKzOVU5OjN6PD;hQi=>
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MCF7 MnTqR5l1d3SxeHnjbZR6KGG|c3H5 NEnyU2c4OiCqcoO= MYLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC3MlM{KM7:TT6= MmP0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4NESxPVMoRjJ|NkS0NVk{RC:jPh?=
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HeLa M{PUOGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NVXUUWdiPzJiaILz M{THVGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXMZUBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNEOuO|Eh|ryPLh?= M{LuNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|Nk[1NVA3Lz5{M{[2OVExPjxxYU6=
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A549 M{XMXGN6fG:2b4jpZ4l1gSCjc4PhfS=> NYjF[mx[PzJiaILz MlWzR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gPE44OSEQvF2u M{LsRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|Nki1OVcyLz5{M{[4OVU4OTxxYU6=
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HepG2 NX3mSmFGS3m2b4TvfIlkcXS7IHHzd4F6 MVW3NkBpenN? NVOzV2hQS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ2Lkm2JO69VS5? Mon0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4OEW1O|EoRjJ|Nki1OVcyRC:jPh?=
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