Fluorouracil (5-Fluorouracil, 5-FU)

For research use only. Not for use in humans.

目录号:S1209 别名: NSC 19893 中文名称:氟尿嘧啶

Fluorouracil (5-Fluorouracil, 5-FU) Chemical Structure

CAS No. 51-21-8

Fluorouracil (5-Fluorouracil, 5-FU, NSC 19893) 是DNA/RNA合成抑制剂,在肿瘤细胞中通过抑制胸苷酸合成酶(TS)而干扰核苷酸合成。Fluorouracil 可诱导细胞凋亡并可用于治疗HIV。

规格 价格 库存 购买数量  
10mM (1mL in DMSO) RMB 1091.79 现货
RMB 1187.43 现货
RMB 1799.08 现货
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客户使用Selleck生产的Fluorouracil (5-Fluorouracil, 5-FU)发表文献112篇:

产品安全说明书

DNA/RNA Synthesis抑制剂选择性比较

生物活性

产品描述 Fluorouracil (5-Fluorouracil, 5-FU, NSC 19893) 是DNA/RNA合成抑制剂,在肿瘤细胞中通过抑制胸苷酸合成酶(TS)而干扰核苷酸合成。Fluorouracil 可诱导细胞凋亡并可用于治疗HIV。
靶点
Thymidylate synthase [1]
(Tumor cells)
体外研究

Adrucil是一种尿嘧啶类似物,在C-5位置上有一个氟原子。利用和尿嘧啶一致的转运途径快速进入细胞。Adrucil在细胞内转化成几个活性代谢物:氟脱氧尿苷单磷酸盐(FdUMP),氟脱氧尿苷三磷酸盐(FdUTP) 以及氟尿苷三磷酸盐 (FUTP)。Adrucil的代谢物FdUMP结合到TS核苷酸结合位点,与CH2THF形成稳定的三聚体,进而阻断了正常的底物dUMP的结合,抑制了dTMP的合成。Adrucil代谢物能够插入DNA,导致DNA双链断裂和细胞死亡。Adrucil的促凋亡作用可能和激活肿瘤抑制因子P53有关。P53功能缺失降低细胞对Adrucil的敏感性。[1]Adrucil抑制存活诱导各种细胞的凋亡。Adrucil 抑制鼻咽癌细胞系CNE2 和 HONE的生存能力[2],Adrucil抑制Capan-1细胞的生存能力[3],Adrucil抑制HT-29细胞的生存能力[4],IC50 分别是 9 μg/mL, 3 μg/mL, 0.22 μM, 2.5 μM。

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H292 Mnm1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mo[2O|LDqGkEoB?= M1LWSmlEPTB-IEK1JO69\y:vTB?= MlzCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyOUWxO|YoRjJ2MEm1NVc3RC:jPh?=
HL-60 MmOwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmfvO|LDqGkEoB?= NWPTT|hjUUN3ME24MlYxOSEQvHevcWw> Mn;GQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyOUWxO|YoRjJ2MEm1NVc3RC:jPh?=
HT-29 NUjYZ4JoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXq3NuKhcMLi MX3JR|UxRiB{NTFOwIcwdUx? NYHESGdGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwPVUyPzZpPkK0NFk2OTd4PD;hQi=>
MCF-7 NWjP[FN1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEixOJE4OsLiaNMg NXq4U5dGUUN3ME2yNEDPxGdxbVy= M3jOZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MEm1NVc3Lz5{NEC5OVE4PjxxYU6=
L1210/0 NFr5bVJHfW6ldHnvckBie3OjeR?= NIroTnJG\m[nY4Sgc44hVDF{MUCvNEBk\WyuczDpckBkfWy2dYLlMEBKSzVyIE2gNE4{KM7:TT6= M3LqRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NkKyO|goRjJ|NkKyO|g9N2F-
CCRF-CEM M4PCOWZ2dmO2aX;uJIF{e2G7 NHnvSXpG\m[nY4Sgc44hS0OURj3DSW0h[2WubIOgbY4h[3WudIXy[UwhUUN3MDC9JFIh|ryPLh?= MkHpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4MkK3PEc,OjN4MkK3PFww[T5?
P388 NGX3V4dCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MWm0PEBpenN? M1voZmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViUEO4PEBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMD62NFkh|ryPLh?= MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzd6NES5K|4zPzd6NES5QE9iRg>?
HT-29 MoT3RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? M2O4Rlk3KGi{cx?= NEixTI5CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjUMVI6KGOnbHzzJIFnfGW{IEm2JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlY6KM7:TT6= NH3OOpM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{e4OFQ6Lz5{N{e4OFQ6RC:jPh?=
L1210 NFjMTVdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkHSTY5pcWKrdHnvckBw\iClZXzsJIdzd3e2aDDv[kBNOTJzMDDtc5V{\SCOZYXr[Y1q[SClZXzsd{whUUN3MDC9JFAvOyEQvF2u MoD5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl4N{O3OUc,Ojl4N{O3OVww[T5?
L1210 Mn30S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2HIS2NwdmOnboTyZZRqd25icnXxeYlz\WRiZn;yJJRp\SB3MDWgbY5pcWKrdHnvckBw\iCpcn;3eIghd2ZiTEGyNVAhdW:3c3WgcIV2c2WvaXGgZ4VtdHNiaX6gZ5VtfHW{ZTygTWM2OCB;IECuOUDPxE1w Mnm5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwPzF{MEK5NEc,PzF{MEK5NFww[T5?
CCRF-CEM M1\XVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mm\2R49v[2WwdILheIlwdiC{ZYH1bZJm\CCob4KgeIhmKDVyJTDpcohq[mm2aX;uJI9nKGe{b4f0bEBw\iCFQ2LGMWNGVSCqdX3hckBt\XWtZX3pZUBk\WyuczDpckBkfWy2dYLlMEBKSzVyIE2gOUDPxE1w M3\XcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzdzMkCyPVAoRjdzMkCyPVA9N2F-
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L1210 MnXoS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFPTRnMzKGi{cx?= NUX2RpdYUW5idnn0do8h\3Kxd4ToJIlvcGmkaYTpc44hd2ZiTEGyNVAh[2WubIOgNkBpd3W{czDh[pRmeiCjZH3pcol{fHKjdHnvckBw\iClb33wc5Vv\CxiSVO1NEA:KDJwMjFOwG0v NV31VW9NRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxN{[yPVgxPid-N{[yPVgxPjxxYU6=
CHO NVjNd41CT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3W3TGdzd3e2aDDpcohq[mm2b4L5JIFkfGm4aYT5JIFo[Wmwc4SgR2hQKGOnbHzzJIlvKGO3bIT1doUvNCCLQ{WwJF0hPSEQvF2u NYTEVVhORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxN{i1N|M1Oid-N{i1N|M1OjxxYU6=
SCLC MXLDfZRwfG:6aXPpeJkh[XO|YYm= MUPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTR2xEKGOnbHzzJJJme2m|dHHueEB1dyClaYPwcIF1cW5iKGPDUGMwS0SGUDmsJGlEPTBiPTC4MlQh|ryPLh?= M4PENVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzh{NUi4N|UoRjh{NUi4N|U9N2F-
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SK-MEL-28 NFW3e29CdnSrY3HuZ4VzKGG|c3H5 NWLaTGxrXGW|dHXkJIlvKH[rdILvJIZweiCjboTpZ4Fv[2W{IHHjeIl3cXS7IHHnZYlve3RiU1utUWVNNTJ6IHPlcIx{NCCLQ{WwJF0hPC53IN88UU4> MlruQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTByN{K2PFMoRjFyMEeyOlg{RC:jPh?=
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SK-MES-1 MnHSRY51cWOjbnPldkBie3OjeR?= M4HJd3Rme3SnZDDpckB3cXS{bzDmc5Ih[W62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KFONLV3FV{0yKGOnbHzzMEBKSzVyIE2gNVMvOSEQvF2u M3:yVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFyMEeyOlg{Lz5zMEC3NlY5OzxxYU6=
HepG2 M2fhVmFvfGmlYX7j[ZIh[XO|YYm= M{fwV3Rme3SnZDDpckB3cXS{bzDmc5Ih[W62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KEincFeyJINmdGy|LDDJR|UxKD1iM{euPUDPxE1w Mlm0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTByN{K2PFMoRjFyMEeyOlg{RC:jPh?=
MCF-7 MV\BcpRq[2GwY3XyJIF{e2G7 NEjnR4dV\XO2ZXSgbY4hfmm2cn:g[o9zKGGwdHnjZY5k\XJiYXP0bZZqfHliYXfhbY5{fCCPQ1[tO{Bk\WyuczygTWM2OCB;IESxJO69VS5? MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yODB5Mk[4N{c,OTByN{K2PFM9N2F-
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NCI-H522 NHTtTVFCdnSrdIXtc5Ih[XO|YYm= MX3BcpRqfHWvb4KgZYN1cX[rdImgZYdicW6|dDDoeY1idiCQQ1mtTFUzOiClZXzsd{whT0l3MDC9JFM6NjhzMEeg{txONg>? MmDvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2NE[wO|coRjF5NES2NFc4RC:jPh?=
NCI/ADR-RES M2XXNmFvfGm2dX3vdkBie3OjeR?= Ml[xRY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJM2FFWi2URWOgZ4VtdHNuIFfJOVAhRSB|OT64NVA4KM7:TT6= NGXZV|M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S0OlA4Pyd-MUe0OFYxPzd:L3G+
SW480 NGLMeJJCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M{jBNFczKGi{cx?= NHyzOHBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPXOFgxKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQhdWW2aH;kMEBKSzVyIE2gPE4yKM7:TT6= MoPHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3MkS2OVUoRjF5NUK0OlU2RC:jPh?=
MDA-MB-435S NGrXSnhCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MoT2O|IhcHK| MnfDRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPRFGtUWIuPDN3UzDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIH3leIhw\CxiSVO1NEA:KDF2LkWg{txONg>? NF7rXIg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{WyOFY2PSd-MUe1NlQ3PTV:L3G+
HCCLM7 NXPLbZZoSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NGraWnM4OiCqcoO= MVHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEiFQ1zNO{Bk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJI1mfGixZDygTWM2OCB;IEG4MlYh|ryPLh?= NXPTc5dORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe1NlQ3PTVpPkG3OVI1PjV3PD;hQi=>
Caco-2 NGHi[GNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVnHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDDZYNwNTJiY3XscJMtKEmFNUCgQUAyNjVizszNMi=> NVzGU5RORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe1OFgyOjlpPkG3OVQ5OTJ7PD;hQi=>
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HCT116 NFXVZnNCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MX[3NkBpenN? MkH0RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKQ2SxNVYh[2WubIOgZYZ1\XJiN{KgbJJ{NCCLQ{WwJF0hOi56IN88UU4> NInv[2U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{W0PFE6QCd-MUe1OFgyQTh:L3G+
SW480 NH;yWHRCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MmKxO|IhcHK| Mm[0RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCVV{S4NEBk\WyuczDh[pRmeiB5MjDodpMtKEmFNUCgQUA{NjVizszNMi=> MkLxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NEixPVgoRjF5NUS4NVk5RC:jPh?=
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DLD1 NGDCbGdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWDQeXNrT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hTEyGMTDj[YxteyxiSVO1NEA:KDRwNTFOwG0v M3zhOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUWzOlg2Lz5zN{W1N|Y5PTxxYU6=
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colon cancer cell MlnUR5l1d3SxeHnjbZR6KGG|c3H5 MnzuR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gZ49td25iY3HuZ4VzKGOnbHzzMEBIUTVyIE2gOU44PSEQvF2u MnfpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NkKzOlUoRjF5NU[yN|Y2RC:jPh?=
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Molt4/C8 Mkm1R5l1d3O2YYTpZ{Bi[3Srdnn0fUBie3OjeR?= NWHMRoJXS3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG1wdHR2L1O4JINmdGy|LDDJR|UxKD1iMkOg{txONg>? MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzl|MUi2Nkc,OTd7M{G4OlI9N2F-
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MCF7 MVzBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MmrzN{Bl[Xm| MWTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhOyCmYYnzJIJ6KFOUQjDhd5NigSxiSVO1NEA:KDRwM{Kg{txONg>? NVn5d|lLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUiwOlkxQTNpPkG4NFY6ODl|PD;hQi=>
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embryonic cell NY\XV4t1TnWwY4Tpc44h[XO|YYm= M1PESWlv\HWldHnvckBw\iClbHXheoFo\SCjcoLld5QhcW5iZX3idplwdmmlIHPlcIx{KG:oIIP0ZYdmKDhiWHXuc5B2eyCuYXX2bZMh[myjc4T1cIFmNCCLQ{WwJF0hOjZwODFOwG0v NH;QRnc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEK3NVU2QCd-MUiyO|E2PTh:L3G+
HepG2 MlfvR5l1d3SxeHnjbZR6KGG|c3H5 NX\QdVFkS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNuIFnDOVAhRSBzOD63JO69VS5? NVm4XYhGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUizNFI{OzZpPkG4N|AzOzN4PD;hQi=>
L1210 M1TqUWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MnHBNkBl[Xm| M123WmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViTEGyNVAh[2WubIOgZYZ1\XJiMjDkZZl{KGK7IF3UWEBie3OjeTygTWM2OCB;IECuOlkh|ryPLh?= M2jH[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEK0NVU2Lz5zOESyOFE2PTxxYU6=
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MiaPaCa2 M{PXe2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 MlfjN{Bl[Xm| NX3NV4hVSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNbYFR[UOjMjDj[YxteyCjZoTldkA{KGSjeYOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPi53IN88UU4> NXS4b|VZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0NlQyPTVpPkG4OFI1OTV3PD;hQi=>
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HepG2 M37JSWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MWizJIRigXN? NHzqTGRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjldGczKGOnbHzzJIFnfGW{IEOg[IF6eyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC5MlIh|ryPLh?= MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR{NEG1OUc,OTh2MkSxOVU9N2F-
CEM NYDhOnpVSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= Mo\1N{Bl[Xm| MkXZRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCFRV2gZ4VtdHNiYX\0[ZIhOyCmYYnzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDlwMkOg{txONg>? MmS0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2MkSxOVUoRjF6NEK0NVU2RC:jPh?=
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HeLa NH\PXoRCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M{f1e|Mh\GG7cx?= Mnz4RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKZVzhJINmdGy|IHHmeIVzKDNiZHH5d{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzNjFOwG0v MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR{NEG1OUc,OTh2MkSxOVU9N2F-
Molt4/C8 NVnXS3FLSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NIfaZog{KGSjeYO= MXTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2xbIS0M2M5KGOnbHzzJIFnfGW{IEOg[IF6eyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyNEDPxE1w M2jHblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEK0NVU2Lz5zOESyOFE2PTxxYU6=
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Hep2 NEDOS2RCdnSrY3HuZ4VzKGG|c3H5 MkPIOFghcHK| NGDBTXZCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTIVxOiClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJZq[WKrbHn0fUBi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gNE4{KM7:TT6= MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTB5NES0OEc,OjFyN{S0OFQ9N2F-
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HepG2 MVTDfZRwfG:6aXPpeJkh[XO|YYm= M2r5Z|czKGi{cx?= MWnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gN|IvOjJizszNMi=> M3nuS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{Nki3O|Q2Lz5{Mk[4O|c1PTxxYU6=
NCI-H460 MmmwR5l1d3SxeHnjbZR6KGG|c3H5 M2jkfVczKGi{cx?= M1vOWmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG5EUS2KNE[wJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{LkSg{txONg>? MoLDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ5Mke0OFUoRjJ{N{K3OFQ2RC:jPh?=
BGC823 NFvURm1EgXSxdH;4bYNqfHliYYPzZZk> Mk\oO|IhcHK| M1Xte2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGJISzh{MzDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPC53IN88UU4> MlnUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ5Mke0OFUoRjJ{N{K3OFQ2RC:jPh?=
HepG2 NU\oNYxNS3m2b4TvfIlkcXS7IHHzd4F6 NWPZdIF{PzJiaILz NFnpW|VEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPC56IN88UU4> MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjd{N{S0OUc,OjJ5Mke0OFU9N2F-
SGC7901 MVvDfZRwfG:6aXPpeJkh[XO|YYm= NYTSRmt1PzJiaILz MUHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTS2M4QTBzIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA3NjNizszNMi=> MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjd{N{S0OUc,OjJ5Mke0OFU9N2F-
MCF7 NVLMTWVQS3m2b4TvfIlkcXS7IHHzd4F6 MnjaO|IhcHK| MlLYR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVIvPSEQvF2u MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjd{N{S0OUc,OjJ5Mke0OFU9N2F-
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MCF7 MnfZR5l1d3SxeHnjbZR6KGG|c3H5 NWDaZpVbPzJiaILz NHi2RVZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyPC5{IN88UU4> NGDpU2k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mke0PVE6Oid-MkK3OFkyQTJ:L3G+
CNE2 M{\2[2N6fG:2b4jpZ4l1gSCjc4PhfS=> MoLvO|IhcHK| M1jPcmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGNPTTJiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE2NjFizszNMi=> NEPycIg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mke0PVE6Oid-MkK3OFkyQTJ:L3G+
GLC82 NVmzTm5sS3m2b4TvfIlkcXS7IHHzd4F6 MUS3NkBpenN? M2HCcWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGdNSzh{IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyPy52IN88UU4> MorsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ5NEmxPVIoRjJ{N{S5NVkzRC:jPh?=
MGC803 MnfWR5l1d3SxeHnjbZR6KGG|c3H5 M16z[|czKGi{cx?= MVHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNS2M5ODNiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE5NjVizszNMi=> NXi2VIxrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK3OFkyQTJpPkKyO|Q6OTl{PD;hQi=>
MCF7 NEPheFNCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MX[3NkBpenN? MmnBRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPQ1[3JINmdGy|IHHmeIVzKDd{IHjyd{BjgSClconzeIFtKH[rb3zleEB{fGGrbnnu[{Bu\XSqb3SsJGlEPTBiPTC0Mlch|ryPLh?= M3jBNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{N{[1PFk4Lz5{Mke2OVg6PzxxYU6=
HT-29 M4nxVmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M4jaelczKGi{cx?= M1Oz[mFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSGStNlkh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IHPyfZN1[WxidnnvcIV1KHO2YXnubY5oKG2ndHjv[EwhUUN3MDC9JFcvOyEQvF2u NXH1e|B5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK3OlU5QTdpPkKyO|Y2QDl5PD;hQi=>
MDA-MB-231 MUDBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MkDlO|IhcHK| MYLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2GQT3NRk0zOzFiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JINzgXO2YXygeolwdGW2IIP0ZYlvcW6pIH3leIhw\CxiSVO1NEA:KDlwNjFOwG0v M2TPc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{N{[1PFk4Lz5{Mke2OVg6PzxxYU6=
HT1080 NH[5ZXBEgXSxdH;4bYNqfHliYYPzZZk> MYTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWFExQDBiY3XscJMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMz6wOkDPxE1w Mle3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6MEG2OFQoRjJ{OECxOlQ1RC:jPh?=
A375-S2 MXrDfZRwfG:6aXPpeJkh[XO|YYm= MYXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBN|c2NVN{IHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OCB;IEmuPVIh|ryPLh?= NXXKS2FQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4NFE3PDRpPkKyPFAyPjR2PD;hQi=>
HeLa M4PzU2N6fG:2b4jpZ4l1gSCjc4PhfS=> NUH3eFB5S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNE4{PiEQvF2u M4DER|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OECxOlQ1Lz5{MkiwNVY1PDxxYU6=
HepG2 M13VNmN6fG:2b4jpZ4l1gSCjc4PhfS=> M3Owc2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGwMlQ2KM7:TT6= MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjhyMU[0OEc,OjJ6MEG2OFQ9N2F-
BGC823 MUHDfZRwfG:6aXPpeJkh[XO|YYm= MmO5R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRmdEQDJ|IHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OCB;IEG1MlY2KM7:TT6= MnHSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6MEG2OFQoRjJ{OECxOlQ1RC:jPh?=
Hep2 M4nNU2N6fG:2b4jpZ4l1gSCjc4PhfS=> NUTDb5Y3S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyMjDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyOE42QCEQvF2u MkP4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6MEG2OFQoRjJ{OECxOlQ1RC:jPh?=
MCF7 M4PlXmN6fG:2b4jpZ4l1gSCjc4PhfS=> NFrO[5ZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OCB;IEK0MlU5KM7:TT6= NX72UmpqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4NFE3PDRpPkKyPFAyPjR2PD;hQi=>
A549 M4W0VGN6fG:2b4jpZ4l1gSCjc4PhfS=> NETXSWZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OCB;IEOxMlUzKM7:TT6= NIK4eZg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkiwNVY1PCd-MkK4NFE3PDR:L3G+
MDA231 M1K3eGN6fG:2b4jpZ4l1gSCjc4PhfS=> MUHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNSGEzOzFiY3XscJMh[nliTWTUJIF{e2G7LDDJR|UxKD1iM{GuOVch|ryPLh?= NEHDVVI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkiwNVY1PCd-MkK4NFE3PDR:L3G+
PC3 M2fpSmN6fG:2b4jpZ4l1gSCjc4PhfS=> Mn3hR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gVGM{KGOnbHzzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDN3Lke1JO69VS5? NUjaN3JmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4NFE3PDRpPkKyPFAyPjR2PD;hQi=>
PC3M NVLRUXJRS3m2b4TvfIlkcXS7IHHzd4F6 NETTWYY1QCCqcoO= NGrpV4tEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSzOPIHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzOi54MzFOwG0v MoDPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6MEm1OVgoRjJ{OEC5OVU5RC:jPh?=
A549 NY\FeWZES3m2b4TvfIlkcXS7IHHzd4F6 M{fjWFQ5KGi{cx?= NV;F[JhRS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOzVwNEGg{txONg>? MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjhyOUW1PEc,OjJ6MEm1OVg9N2F-
MKN45 M4DrOmN6fG:2b4jpZ4l1gSCjc4PhfS=> NFnQdJo1QCCqcoO= MljpR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWtPPDViY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQyNjd|IN88UU4> M37iTVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OEC5OVU5Lz5{MkiwPVU2QDxxYU6=
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LoVo MY\BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NE\ie|A1QCCqcoO= NHvHTW5CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFzvWo8h[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEOuN{DPxE1w M{HoU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OESwOFk{Lz5{Mki0NFQ6OzxxYU6=
A549 MUHBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MXK0PEBpenN? NV3ZVpE{SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNk45KM7:TT6= MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjh2MES5N{c,OjJ6NEC0PVM9N2F-
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leukemia NIr0XJBCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NGXmdIE1QCCqcoO= MmDPRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCuZYXr[Y1q[SClZXzsd{Bi\nSncjC0PEBpenNiYomgZ4VtdCClb4XueIlv\yCjbnHsfZNqeyxiR1m1NEA:KDF3LkGg{txONg>? MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjl7NU[yNUc,OjJ7OUW2NlE9N2F-
prostate cancer MXrBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MkfVOFghcHK| MXPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKHC{b4P0ZZRmKGOjbnPldkBk\WyuczDh[pRmeiB2ODDodpMh[nliY3XscEBkd3WwdHnu[{BidmGueYPpd{whT0l3MDC9JFIzNjdizszNMi=> NGW0[3g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mkm5OVYzOSd-MkK5PVU3OjF:L3G+
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MNK45 M4XuNWN6fG:2b4jpZ4l1gSCjc4PhfS=> MnXhOFghcHK| NIXKSZhEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOVkt2NTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTJizszNMi=> MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzByMkmyOEc,OjNyMEK5NlQ9N2F-
HepG2 NVXCfYNHSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MV[0PEBpenN? M2DrUWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXwS|Ih[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBu\XSqb3SsJGlEPTBiPTCxMlMh|ryPLh?= NVvtR2xIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwNVgxQTZpPkKzNFE5ODl4PD;hQi=>
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SW1116 Mon6RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? M3TwUlQ5KGi{cx?= M1vzT2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU2exNVE3KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQhdWW2aH;kMEBKSzVyIE2gNk41OSEQvF2u MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzBzOEC5Okc,OjNyMUiwPVY9N2F-
HeLa NVvv[XBOSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NXfTcYtlPDhiaILz NUft[mZ4SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQhdWW2aH;kMEBKSzVyIE2gN{4zPSEQvF2u Mn;lQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNyMUiwPVYoRjJ|MEG4NFk3RC:jPh?=
A549 M3fq[WN6fG:2b4jpZ4l1gSCjc4PhfS=> NWfMTIJrPDhiaILz MlrIR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bie3Onc4Pl[EBk\WyuII\pZYJqdGm2eTDh[pRmeiB2ODDodpMh[nliU2LCJIF{e2G7LDDJR|UxKD1iND6yNUDPxE1w NEDKUms9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{C0OFM4OCd-MkOwOFQ{PzB:L3G+
HT1080 MXzDfZRwfG:6aXPpeJkh[XO|YYm= NFO2dnE1QCCqcoO= NF;VO4ZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXDFyOECgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF3LkKg{txONg>? MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzB4N{W0PUc,OjNyNke1OFk9N2F-
HCT116 NELJTZBEgXSxdH;4bYNqfHliYYPzZZk> Mn7hOFghcHK| MlXWR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVOTF4IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA{Pi52IN88UU4> M{W0VlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|ME[3OVQ6Lz5{M{C2O|U1QTxxYU6=
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B16F10 NHzX[|hCdnSrY3HuZ4VzKGG|c3H5 MVm0PEBpenN? MYTBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViQkG2SlExKGOnbHzzJIF{e2W|c3XkJIF{KGOnbHygd5Vzfmm4YXygcYVie3W{ZXSgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEKxMlQyKM7:TT6= M3fNd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|M{GyPVQ6Lz5{M{OxNlk1QTxxYU6=
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leukemia MVzDfZRwfG:6aXPpeJkh[XO|YYm= M2rTT|Q5KGi{cx?= MYjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDs[ZVs\W2rYTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WucHjvdohw\GGvaX7lJGIh[XO|YYmsJGdKPTBiPTCxOU4yKM7:TT6= MnLGQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN2N{S4PVkoRjJ|NEe0PFk6RC:jPh?=
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HL60 NITJflNEgXSxdH;4bYNqfHliYYPzZZk> M1;iXVQ5KGi{cx?= MV\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIUFYxKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNE4xPSEQvF2u MmK0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN3NUiyN|goRjJ|NUW4NlM5RC:jPh?=
MCF7 MYHDfZRwfG:6aXPpeJkh[XO|YYm= MlnEOFghcHK| Ml\NR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVEvPSEQvF2u MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzV3OEKzPEc,OjN3NUiyN|g9N2F-
K562 NFjUd5ZEgXSxdH;4bYNqfHliYYPzZZk> MlfuOFghcHK| MofLR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT|U3OiClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlMvPTVizszNMi=> MoHNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN3NUiyN|goRjJ|NUW4NlM5RC:jPh?=
U937 MlfYR5l1d3SxeHnjbZR6KGG|c3H5 NXzCU|BqPDhiaILz NYDkUXFqS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hXTl|NzDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOjNwOUOg{txONg>? M4TJNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NUW4NlM5Lz5{M{W1PFI{QDxxYU6=
HCT116 NITTdoJEgXSxdH;4bYNqfHliYYPzZZk> MlL2OFghcHK| NYHOOlZqS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUG2JINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{Nz63OkDPxE1w MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzV3OEKzPEc,OjN3NUiyN|g9N2F-
HT1080 MnjBR5l1d3SxeHnjbZR6KGG|c3H5 NU\SUVl5PDhiaILz NFju[YZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXDFyOECgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDN3Lk[yJO69VS5? NHm1em49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{W1PFI{QCd-MkO1OVgzOzh:L3G+
HepG2 MnizR5l1d3SxeHnjbZR6KGG|c3H5 MmTUOFghcHK| MnnlR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQxNjN2IN88UU4> MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzV3OEKzPEc,OjN3NUiyN|g9N2F-
A549 NHj3dYVEgXSxdH;4bYNqfHliYYPzZZk> NUPNfG1CPDhiaILz NVLIUFB5S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPDRwMEWg{txONg>? M33oZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NUW4NlM5Lz5{M{W1PFI{QDxxYU6=
EC9706 M3;zeGN6fG:2b4jpZ4l1gSCjc4PhfS=> NIriV4c4OiCqcoO= MnXqR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gSWM6PzB4IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjN{IN88UU4> NYm1dpRLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2OFQyQTNpPkKzOlQ1OTl|PD;hQi=>
MGC803 Mlv4R5l1d3SxeHnjbZR6KGG|c3H5 NFLzZnc4OiCqcoO= NYXkR|FDS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUeFOECzJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB5LkG0JO69VS5? NGTYeXk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{[0OFE6Oyd-MkO2OFQyQTN:L3G+
MCF7 M{LF[WN6fG:2b4jpZ4l1gSCjc4PhfS=> MnzrO|IhcHK| NFfSUGVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA4NjN|IN88UU4> MnfwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4NESxPVMoRjJ|NkS0NVk{RC:jPh?=
SMMC7721 NWjM[G5[S3m2b4TvfIlkcXS7IHHzd4F6 NYTFd5VxPzJiaILz MmHuR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gV21OSzd5MkGgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ4LkexJO69VS5? M{fmblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NkS0NVk{Lz5{M{[0OFE6OzxxYU6=
HCT116 NIXGWoJEgXSxdH;4bYNqfHliYYPzZZk> MkDDOFghcHK| NVLNOmF4S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUG2JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBKSzVyIE2gOE42OiEQvF2u MnrIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4NESyNVUoRjJ|NkS0NlE2RC:jPh?=
HT-29 MoLlR5l1d3SxeHnjbZR6KGG|c3H5 NXfQeIJ3PDhiaILz MWLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWE0zQSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiSVO1NEA:KDZwM{Wg{txONg>? MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzZ2NEKxOUc,OjN4NESyNVU9N2F-
A549 M3v0Z2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 NYLFUm52PzJiaILz NH3JbHVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG1OFkh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEOuOVIh|ryPLh?= NV[0c28yRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2OlUyODZpPkKzOlY2OTB4PD;hQi=>
HCT116 NEPn[HNCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MoLMO|IhcHK| NIfwbIJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDWFEyPiClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOU42OyEQvF2u MlfzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4NkWxNFYoRjJ|Nk[1NVA3RC:jPh?=
HT-29 MnvZRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NYDKbIxbPzJiaILz NFXzS4FCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjUMVI6KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyOE42KM7:TT6= M2q0c|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|Nk[1NVA3Lz5{M{[2OVExPjxxYU6=
MCF7 MXHBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? Mm\VO|IhcHK| NF7XT|FCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3DSlch[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEOyMlE5KM7:TT6= M{LZd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|Nk[1NVA3Lz5{M{[2OVExPjxxYU6=
HeLa NH2yfZBCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NUOxWXZQPzJiaILz MVjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEinTHGgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDR|LkexJO69VS5? M37CWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|Nk[1NVA3Lz5{M{[2OVExPjxxYU6=
colon cancer NELmXmJEgXSxdH;4bYNqfHliYYPzZZk> NHfkXI01QCCqcoO= MkHKR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gZ49td25iY3HuZ4VzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDjc5VtfGW{IHPveY51\XJiYX7hcJl{cXNuIFfJOVAhRSB6LkSg{txONg>? MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzZ6M{W5Nkc,OjN4OEO1PVI9N2F-
leukemia MVHDfZRwfG:6aXPpeJkh[XO|YYm= M3fOOlQ5KGi{cx?= NE\zbnlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBt\XWtZX3pZUBk\WyuczDh[pRmeiB2ODDodpMh[nliY3;1cJRmeiClb4XueIVzKGGwYXz5d4l{NCCJSUWwJF0hOTVwMTFOwG0v M2nsOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NkizOVkzLz5{M{[4N|U6OjxxYU6=
prostate cancer NEDTRXREgXSxdH;4bYNqfHliYYPzZZk> NXWzWYlIPDhiaILz NVn2eVd3S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4heHKxc4TheIUh[2GwY3XyJINmdGy|IHHmeIVzKDR6IHjyd{BjgSClb4XseIVzKGOxdX70[ZIh[W6jbInzbZMtKEeLNUCgQUAzOi55IN88UU4> NWXDVpUzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2PFM2QTJpPkKzOlg{PTl{PD;hQi=>
renal cancer M3\z[2N6fG:2b4jpZ4l1gSCjc4PhfS=> NVewOZg4PDhiaILz NUewXml4S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hemWwYXygZ4Fv[2W{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBkd3WudHXyJINwfW62ZYKgZY5idHm|aYOsJGdKPTBiPTC0OU43KM7:TT6= MlnVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4OEO1PVIoRjJ|NkizOVkzRC:jPh?=
SH-SY5Y NH3mVWtEgXSxdH;4bYNqfHliYYPzZZk> MXS3NkBpenN? M3W5WGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNJNVO\NWmgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwOUeg{txONg>? NFPFcJQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{[4OVU4OSd-MkO2PFU2PzF:L3G+
HCT116 MUTDfZRwfG:6aXPpeJkh[XO|YYm= M13rZVczKGi{cx?= Mk\ZR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVOTF4IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA{NjJ2IN88UU4> MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzZ6NUW3NUc,OjN4OEW1O|E9N2F-
A549 M4D2NmN6fG:2b4jpZ4l1gSCjc4PhfS=> M3;2bFczKGi{cx?= MUPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC4MlcyKM7:TT6= NF\KfW09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{[4OVU4OSd-MkO2PFU2PzF:L3G+
Vero NEH5TIVEgXSxdH;4bYNqfHliYYPzZZk> NInTfVk4OiCqcoO= MlqxR5l1d3SxeHnjbZR6KGGpYXnud5QhSW[{aXPhckBoemWnbjDtc45s\XliVnXyc{Bk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iOT63NUDPxE1w MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzZ6NUW3NUc,OjN4OEW1O|E9N2F-
MCF7 NX3qXpdYS3m2b4TvfIlkcXS7IHHzd4F6 NIjpWnQ4OiCqcoO= MV;DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxNE4yPCEQvF2u MmKyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4OEW1O|EoRjJ|Nki1OVcyRC:jPh?=
HepG2 NVrQUZJbS3m2b4TvfIlkcXS7IHHzd4F6 NUPLdWliPzJiaILz MWLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlQvQTZizszNMi=> NXnpT4hNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2PFU2PzFpPkKzOlg2PTdzPD;hQi=>
PC3 MkP4RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NEjqPGw4OiCqcoO= MX7BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFCFMzDj[YxteyCneIDy[ZN{cW6pIGPLVFIh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI4NjB5IN88UU4> MmrwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN5M{WyPFEoRjJ|N{O1NlgyRC:jPh?=
PC3 NYXQd3FzSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= M1nJZVczKGi{cx?= NIf1bpBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGDDN{Bk\WyuczDlfJBz\XO|aX7nJHBETE6DIHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|MT60OEDPxE1w NYH1U|BmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO3N|UzQDFpPkKzO|M2OjhzPD;hQi=>
COLO320DM NYS5S4xDS3m2b4TvfIlkcXS7IHHzd4F6 NEnPXlI1QCCqcoO= NGHEb3FEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBEV0yRM{KwSG0h[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEKg{txONg>? NVrOTVc{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO3PVI{PTJpPkKzO|kzOzV{PD;hQi=>
HeLa M3H2TWN6fG:2b4jpZ4l1gSCjc4PhfS=> NVXoNHBmPzJiaILz MWPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzMlQh|ryPLh?= MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzd7Mke2N{c,OjN5OUK3OlM9N2F-
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