Fluorouracil (5-Fluorouracil, 5-FU)

目录号:S1209 别名: NSC 19893 中文名称:氟尿嘧啶

仅限科研使用

Fluorouracil (5-Fluorouracil, 5-FU, NSC 19893) 是DNA/RNA合成抑制剂,在肿瘤细胞中通过抑制胸苷酸合成酶(TS)而干扰核苷酸合成。Fluorouracil 可诱导细胞凋亡并可用于治疗HIV。

Fluorouracil (5-Fluorouracil, 5-FU) Chemical Structure

CAS: 51-21-8

规格 价格 库存 购买数量
10mM (1mL in DMSO) RMB 1091.79 现货
RMB 1187.43 现货
RMB 1799.08 现货
大包装 有超大折扣
大剂量询单有大折扣!

今日订购,明日送达 全国免运费 分装免费 分装成小规格产品(单支最小为1mg)
如1支10mg产品可分装为10支1mg产品

全国免费电话:400-668-6834   |   Email:info@selleck.cn

客户使用Selleck生产的Fluorouracil (5-Fluorouracil, 5-FU)发表文献164篇:

产品安全说明书

DNA/RNA Synthesis抑制剂选择性比较

相关DNA/RNA Synthesis产品

生物活性

产品描述 Fluorouracil (5-Fluorouracil, 5-FU, NSC 19893) 是DNA/RNA合成抑制剂,在肿瘤细胞中通过抑制胸苷酸合成酶(TS)而干扰核苷酸合成。Fluorouracil 可诱导细胞凋亡并可用于治疗HIV。
靶点
Thymidylate synthase [1]
(Tumor cells)
体外研究

Adrucil是一种尿嘧啶类似物,在C-5位置上有一个氟原子。利用和尿嘧啶一致的转运途径快速进入细胞。Adrucil在细胞内转化成几个活性代谢物:氟脱氧尿苷单磷酸盐(FdUMP),氟脱氧尿苷三磷酸盐(FdUTP) 以及氟尿苷三磷酸盐 (FUTP)。Adrucil的代谢物FdUMP结合到TS核苷酸结合位点,与CH2THF形成稳定的三聚体,进而阻断了正常的底物dUMP的结合,抑制了dTMP的合成。Adrucil代谢物能够插入DNA,导致DNA双链断裂和细胞死亡。Adrucil的促凋亡作用可能和激活肿瘤抑制因子P53有关。P53功能缺失降低细胞对Adrucil的敏感性。[1]Adrucil抑制存活诱导各种细胞的凋亡。Adrucil 抑制鼻咽癌细胞系CNE2 和 HONE的生存能力[2],Adrucil抑制Capan-1细胞的生存能力[3],Adrucil抑制HT-29细胞的生存能力[4],IC50 分别是 9 μg/mL, 3 μg/mL, 0.22 μM, 2.5 μM。

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H292 NFfwcZZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX[4fFc6PzMEoHlCpC=> MorZTWM2OD5iMkWg{txoN22O Mo\lQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyOUWxO|YoRjJ2MEm1NVc3RC:jPh?=
HL-60 Ml3sS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXTv[IVDPzMEoHlCpC=> MnLhTWM2OD16Lk[wNUDPxGdxbVy= NHO2TJQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEC5OVE4Pid-MkSwPVUyPzZ:L3G+
HT-29 NEXqUlhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVG1T20yPzMEoHlCpC=> NEDuNIZKSzVyPjCyOUDPxGdxbVy= M1zOXVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MEm1NVc3Lz5{NEC5OVE4PjxxYU6=
MCF-7 NH;5PY5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkjQO|LDqGkEoB?= NVvaOlE2UUN3ME2yNEDPxGdxbVy= MmiyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyOUWxO|YoRjJ2MEm1NVc3RC:jPh?=
L1210/0 NYfUOGdoTnWwY4Tpc44h[XO|YYm= M2HsNWVn\mWldDDvckBNOTJzMD:wJINmdGy|IHnuJIN2dHS3cnWsJGlEPTBiPTCwMlMh|ryPLh?= M17qdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NkKyO|goRjJ|NkKyO|g9N2F-
CCRF-CEM MXjGeY5kfGmxbjDhd5NigQ>? MWTF[oZm[3Rib36gR2NTTi2FRV2gZ4VtdHNiaX6gZ5VtfHW{ZTygTWM2OCB;IEKg{txONg>? MlKwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4MkK3PEc,OjN4MkK3PFww[T5?
P388 NWHPb4RsSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= M3[wVlQ5KGi{cx?= MlzBRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDtc5V{\SCSM{i4JINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSByLk[wPUDPxE1w NV\GSGNuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke3PFQ1QSd-Mke3PFQ1QTxxYU6=
HT-29 MUfBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NWPKNZdbQTZiaILz NYKzVWoxSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIWE0zQSClZXzsd{Bi\nSncjC5OkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNE43QSEQvF2u MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzd6NES5K|4zPzd6NES5QE9iRg>?
L1210 NGm2RlZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1;PfGlvcGmkaYTpc44hd2ZiY3XscEBoem:5dHigc4YhVDF{MUCgcY92e2ViTHX1b4VucWFiY3XscJMtKEmFNUCgQUAxNjNizszNMi=> NEXUVGs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OU[3N|c2Lz5{OU[3N|c2RC:jPh?=
L1210 NWrVdmJoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVXhO|RiS2:wY3XueJJifGmxbjDy[ZF2cXKnZDDmc5IhfGinIEWwKUBqdmirYnn0bY9vKG:oIHfyc5d1cCCxZjDMNVIyOCCvb4Xz[UBt\XWtZX3pZUBk\WyuczDpckBkfWy2dYLlMEBKSzVyIE2gNE42KM7:TT6= NIDKUWg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi95MUKwNlkxLz55MUKwNlkxRC:jPh?=
CCRF-CEM NILuZoZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NX3IV2JCS2:wY3XueJJifGmxbjDy[ZF2cXKnZDDmc5IhfGinIEWwKUBqdmirYnn0bY9vKG:oIHfyc5d1cCCxZjDDR3JHNUOHTTDoeY1idiCuZYXr[Y1q[SClZXzsd{BqdiCldXz0eZJmNCCLQ{WwJF0hPSEQvF2u MojwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwPzF{MEK5NEc,PzF{MEK5NFww[T5?
L1210 M1fJPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnGxOFghcHK| M4DmemlvKH[rdILvJIdzd3e2aDDpcohq[mm2aX;uJI9nKExzMkGwJINmdGy|IES4JIhwfXK|IHHmeIVzKGGmbXnubZN1emG2aX;uJI9nKGOxbYDveY5lNCCLQ{WwJF0hOC5zMjFOwG0v M1HS[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzd4Mkm4NFYoRjd4Mkm4NFY9N2F-
L1210 NHPUeWFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFHneXkzPCCqcoO= MmHqTY4hfmm2cn:g[5Jwf3SqIHnubIljcXSrb36gc4YhVDF{MUCgZ4VtdHNiMkSgbI92enNiYX\0[ZIh[WSvaX7pd5Rz[XSrb36gc4Yh[2:vcH;1coQtKEmFNUCgQUAxNjJ{IN88UU4> MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek84PjJ7OEC2K|44PjJ7OEC2QE9iRg>?
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L1210 MX;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmLpNkBpenN? MUnJckB3cXS{bzDndo94fGhiaX7obYJqfGmxbjDv[kBNOTJzMDDj[YxteyB{IHjveZJ{KGGodHXyJIFldWmwaYP0doF1cW:wIH;mJINwdXCxdX7kMEBKSzVyIE2gNk4zKM7:TT6= NWCwb|dXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxN{[yPVgxPid-N{[yPVgxPjxxYU6=
CHO MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVLHdo94fGhiaX7obYJqfG:{eTDhZ5Rqfmm2eTDh[4FqdnO2IFPIU{Bk\WyuczDpckBkfWy2dYLlMkwhUUN3MDC9JFUh|ryPLh?= NFvMem89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi95OEWzN|QzLz55OEWzN|QzRC:jPh?=
SCLC Ml;CR5l1d3SxeHnjbZR6KGG|c3H5 MWfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTR2xEKGOnbHzzJJJme2m|dHHueEB1dyClaYPwcIF1cW5iKGPDUGMwS0SGUDmsJGlEPTBiPTC4MlQh|ryPLh?= NE\pS3A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi96MkW4PFM2Lz56MkW4PFM2RC:jPh?=
T-24 M3rzbmN6fG:2b4jpZ4l1gSCjc4PhfS=> M3H5cHRme3SnZDDmc5Ih[3m2b4TvfIlkcXS7IHHnZYlve3RiYX70bYdmdiCwZXfheIl3\SCWLUK0JIJt[WSmZYKgZ4Fz[2mwb33hJINmdGy|IHjheolv\yCxbnz5JFMuPSViYX70bYdmdiCneIDy[ZN{cW:wLDDJR|UxKD1iND6xJO69VS5? MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek85PDl4OUK2K|45PDl4OUK2QE9iRg>?
791T NHv1[Y9EgXSxdH;4bYNqfHliYYPzZZk> NYjM[5lnXGW|dHXkJIZweiCleYTveI95cWOrdImgZYdicW6|dDDhcpRq\2WwIIDvd4l1cX[nIEe5NXQhd3O2ZX;zZZJkd22jIHPlcIx{KGijdnnu[{Bwdmy7IEOtOUUh[W62aXflckBmgHC{ZYPzbY9vNCCLQ{WwJF0hPS53IN88UU4> MlrjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwQDR7NkmyOkc,QDR7NkmyOlww[T5?
9L NX\yVHdkSW62aXPhcoNmeiCjc4PhfS=> MkPUWIV{fGWmIHnuJJZqfHKxIH\vdkBidnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhQUxiY3XscJMtKEmFNUCgQUAyKM7:TT6= NEXpe3I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMEC3NlY5Oyd-MUCwO|I3QDN:L3G+
SK-MEL-28 MmLxRY51cWOjbnPldkBie3OjeR?= M2PUbnRme3SnZDDpckB3cXS{bzDmc5Ih[W62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KFONLV3FUE0zQCClZXzsd{whUUN3MDC9JFQvPSEQvF2u NI[1cXo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMEC3NlY5Oyd-MUCwO|I3QDN:L3G+
PBM M{L6b2N6fG:2b4jpZ4l1gSCjc4PhfS=> MYXU[ZN1\WRiaX6geol1em9iZn;yJIN6fG:2b4jpZ4l1gSCjZ3HpcpN1KFCETTDj[YxteyxiSVO1NEA:KDVizszNMi=> MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yODB5Mk[4N{c,OTByN{K2PFM9N2F-
Vero M2jjXWN6fG:2b4jpZ4l1gSCjc4PhfS=> M4LJOHRme3SnZDDpckB3cXS{bzDmc5Ih[3m2b4TvfIlkcXS7IHHnZYlve3RiVnXyc{Bk\WyuczygTWM2OCB;IE[uPFEh|ryPLh?= NEHsSZY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMEC3NlY5Oyd-MUCwO|I3QDN:L3G+
SK-MES-1 MlHXRY51cWOjbnPldkBie3OjeR?= MmPoWIV{fGWmIHnuJJZqfHKxIH\vdkBidnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhW0tvTVXTMVEh[2WubIOsJGlEPTBiPTCxN{4yKM7:TT6= NVHEO3o2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUCwO|I3QDNpPkGwNFczPjh|PD;hQi=>
HepG2 NFHvV|ZCdnSrY3HuZ4VzKGG|c3H5 NXe3dFh2XGW|dHXkJIlvKH[rdILvJIZweiCjboTpZ4Fv[2W{IHHjeIl3cXS7IHHnZYlve3RiSHXwS|Ih[2WubIOsJGlEPTBiPTCzO{46KM7:TT6= NVfncllFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUCwO|I3QDNpPkGwNFczPjh|PD;hQi=>
MCF-7 NVP3UFlRSW62aXPhcoNmeiCjc4PhfS=> NIG1cYpV\XO2ZXSgbY4hfmm2cn:g[o9zKGGwdHnjZY5k\XJiYXP0bZZqfHliYXfhbY5{fCCPQ1[tO{Bk\WyuczygTWM2OCB;IESxJO69VS5? MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yODB5Mk[4N{c,OTByN{K2PFM9N2F-
L1210 NVLhRpNVS3m2b4TvfIlkcXS7IHHzd4F6 NXz5XpBnUW5idnn0do8h[3m2b4TvfIlkcXS7IHHnZYlve3RibYXybY5mKEyndXvlcYliKExzMkGwJINmdGy|LjygTWM2OCB;IECuOlIh|ryPLh?= M{joXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFyMkK5OlM1Lz5zMEKyPVY{PDxxYU6=
KB MUfDfZRwfG:6aXPpeJkh[XO|YYm= MWTJckB3cXS{bzDjfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDvdoFtKGWyaXTldo1wcWRiY3HyZ4lvd22jIFvCJINmdGy|LjygTWM2OCB;IEKuN{DPxE1w NVTFOHRYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUCyNlk3OzRpPkGwNlI6PjN2PD;hQi=>
L1210 NF71U21Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmnqR49v[2WwdILheIlwdiC{ZYH1bZJm\CC2bzDpcohq[mm2IEWwKUBw\iClZXzsJIdzd3e2aDDvckBufXKrbnWgUFEzOTBiY3XscJMvNCCLQ{WwJF0hOC5{ODFOwG0v NUWybJo5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUGwOVI4QThpPkGxNFUzPzl6PD;hQi=>
P388 D1 NIrGWY9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFTUU4VEd26lZX70doF1cW:wIILldZVqemWmIITvJIlvcGmkaYSgOVAmKG:oIHPlcIwh\3Kxd4ToJI9vKG23cnnu[UBROzh6IFSxJINmdGy|LjygTWM2OCB;IECuOFkh|ryPLh?= NXXsOmtrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUGwOVI4QThpPkGxNFUzPzl6PD;hQi=>
Molt 4/C8 MnXTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3;3bGNwdmOnboTyZZRqd25icnXxeYlz\WRidH:gbY5pcWKrdDC1NEUhd2ZiY3XscEBoem:5dHigc44hcHWvYX6gUY9tfCB2L1O4JINmdGy|LjygTWM2OCB;IEKzJO69VS5? MlzpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTFyNUK3PVgoRjFzMEWyO|k5RC:jPh?=
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NCI/ADR-RES NHPJUFNCdnSrdIXtc5Ih[XO|YYm= Mkm5RY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJM2FFWi2URWOgZ4VtdHNuIFfJOVAhRSB|OT64NVA4KM7:TT6= M4LuV|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NES2NFc4Lz5zN{S0OlA4PzxxYU6=
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MDA-MB-435S M4\mRmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NEHhN5Q4OiCqcoO= M2HHW2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVTBMW1DNTR|NWOgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDt[ZRpd2RuIFnDOVAhRSBzND61JO69VS5? MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzV{NE[1OUc,OTd3MkS2OVU9N2F-
HCCLM7 MYLBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MkLsO|IhcHK| NF7sNmFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDR2xOPyClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKG2ndHjv[EwhUUN3MDC9JFE5NjZizszNMi=> NGDvb3U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{WyOFY2PSd-MUe1NlQ3PTV:L3G+
Caco-2 NY\PVpBmT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{XKVGdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGNi[29vMjDj[YxteyxiSVO1NEA:KDFwNTFOwG0v NWqxU49PRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe1OFgyOjlpPkG3OVQ5OTJ7PD;hQi=>
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colon cancer cell M2nPS2N6fG:2b4jpZ4l1gSCjc4PhfS=> NVL3flhCS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4h[2:ub36gZ4Fv[2W{IHPlcIx{NCCJSUWwJF0hPS55NTFOwG0v MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzV4MkO2OUc,OTd3NkKzOlU9N2F-
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CEM NYfWc45bS3m2b4P0ZZRq[yCjY4Tpeol1gSCjc4PhfS=> M4LUemN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDSW0h[2WubIOsJGlEPTBiPTC5JO69VS5? NHrkeYo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{mzNVg3Oid-MUe5N|E5PjJ:L3G+
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embryonic cell M1nNZmZ2dmO2aX;uJIF{e2G7 NWjTSJB3UW6mdXP0bY9vKG:oIHPs[YF3[WenIHHydoV{fCCrbjDlcYJzgW:waXOgZ4VtdHNib3[gd5Ri\2ViODDY[Y5weHW|IHzh[ZZqeyCkbHHzeJVt[WVuIFnDOVAhRSB{Nj64JO69VS5? M4D1U|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MkexOVU5Lz5zOEK3NVU2QDxxYU6=
HepG2 MX;DfZRwfG:6aXPpeJkh[XO|YYm= MnnFR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMtKEmFNUCgQUAyQC55IN88UU4> MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDNyMkOzOkc,OTh|MEKzN|Y9N2F-
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HepG2 M{DiVWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MmrDN{Bl[Xm| M1z0fGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXwS|Ih[2WubIOgZYZ1\XJiMzDkZZl{KGK7IF3UWEBie3OjeTygTWM2OCB;IEmuNkDPxE1w MmT2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2MkSxOVUoRjF6NEK0NVU2RC:jPh?=
CEM NEnqellCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MUizJIRigXN? M1zBOmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQ1XNJINmdGy|IHHmeIVzKDNiZHH5d{BjgSCPVGSgZZN{[XluIFnDOVAhRSB7LkKzJO69VS5? M1j4e|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEK0NVU2Lz5zOESyOFE2PTxxYU6=
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HeLa NYG1TodOS3m2b4TvfIlkcXS7IHHzd4F6 NGS1d2I4OiCqcoO= MlfJR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNE44PyEQvF2u MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR2MEKzN{c,OTh2NECyN|M9N2F-
LLC M2nVW2N6fG:2b4jpZ4l1gSCjc4PhfS=> NEXRVFM4OiCqcoO= NUjyeYw{S3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhVEyFIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzNjV7IN88UU4> Ml;vQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2NECyN|MoRjF6NESwNlM{RC:jPh?=
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Hep3B NXTJT5ZvS3m2b4TvfIlkcXS7IHHzd4F6 M2XZcmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeDOEIHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OCB;IECuOkDPxE1w NYP3b5d2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi2NFY2PDZpPkG4OlA3PTR4PD;hQi=>
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OVCAR5 Mo[4RY51cWOjbnPldkBie3OjeR?= NEnqdng1QCCqcoO= M1HqOGFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDPWmNCWjViY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSBzMD65OlQ5KM7:TT6= NYDOWYsyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3OFA2PzRpPkG5O|QxPTd2PD;hQi=>
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T47D NGDLdVVCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= Ml\rO|IhcHK| MUXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFR2N1SgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwNjFOwG0v Mm\JQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEO4OlMoRjF7N{SzPFY{RC:jPh?=
MES-SA MV3BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M2XXUFczKGi{cx?= MV7BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2HUz3TRUBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMT6xJO69VS5? MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2M{i2N{c,OTl5NEO4OlM9N2F-
SW480 MlnmRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MX63NkBpenN? M2e4fmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU2e0PFAh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEKuNUDPxE1w M370TFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{SzPFY{Lz5zOUe0N|g3OzxxYU6=
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UACC-812 NVTyXpo4SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NICzcmM4OiCqcoO= MXrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFWDQ1OtPFEzKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzMlEh|ryPLh?= M{\FbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{SzPFY{Lz5zOUe0N|g3OzxxYU6=
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SW48 NELYToRCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= Mk\BO|IhcHK| NWmxbFRrSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTW|Q5KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC0MlQh|ryPLh?= MmraQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEO4OlMoRjF7N{SzPFY{RC:jPh?=
HeLa M2HsSGN6fG:2b4jpZ4l1gSCjc4PhfS=> NGTzeGU1QCCqcoO= NH;MZmREgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyOCEQvF2u NF3DXGs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe5OVg1Oyd-MUm3PVU5PDN:L3G+
MCF7 MknJR5l1d3SxeHnjbZR6KGG|c3H5 MXm0PEBpenN? Mn7QR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVUh|ryPLh?= NH3BWmQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe5OVg1Oyd-MUm3PVU5PDN:L3G+
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HT1080 MlHtR5l1d3SxeHnjbZR6KGG|c3H5 NIi4SW04OiCqcoO= MnraR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTHQyODhyIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA2NjJizszNMi=> MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTlzOUC1Nkc,OTl7MUmwOVI9N2F-
HeLa MX\DfZRwfG:6aXPpeJkh[XO|YYm= M1e2[lQ5KGi{cx?= MlXUR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVAh|ryPLh?= NGfwfJk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUmxPVA3PSd-MUm5NVkxPjV:L3G+
MCF7 M1zHVWN6fG:2b4jpZ4l1gSCjc4PhfS=> MYi0PEBpenN? NV3RfoFrS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTVizszNMi=> M2DQWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OUG5NFY2Lz5zOUmxPVA3PTxxYU6=
COLO205 M1XvPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{LjbVQ5KGi{cx?= MkDMS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gR29NVzJyNTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygTWM2OCB;IEKxJO69VS5? NWfOU45vRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm5N|k2OjJpPkG5PVM6PTJ{PD;hQi=>
HCT116 MVzDfZRwfG:6aXPpeJkh[XO|YYm= NHnCdJEzPCCqcoO= NWHEOFY5S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUG2JINmdGy|IHHmeIVzKDJ2IHjyd{BjgSC2conwZY4h[my3ZTDlfINtfXOrb36gZZN{[XluIFnDOVAhRSB|LkCzJO69VS5? NELhe3M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEG2N|g6PSd-MkCxOlM5QTV:L3G+
MOLT4 M1vnbmFvfGm2dX3vdkBie3OjeR?= MnP4NlQhcHK| MVLBcpRqfHWvb4KgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPT1zUOEBk\WyuczDh[pRmeiB{NDDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMD6wN{DPxE1w MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODJzMUW2OEc,OjB{MUG1OlQ9N2F-
H460 MmntRY51cXS3bX;yJIF{e2G7 Mm[zNlQhcHK| NUnYd3U1SW62aYT1cY9zKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTFQ3OCClZXzsd{Bi\nSncjCyOEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNkDPxE1w M{XKcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyMkGxOVY1Lz5{MEKxNVU3PDxxYU6=
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SW620 M3XqW2FvfGm2dX3vdkBie3OjeR?= MXWyOEBpenN? Mn:2RY51cXS3bX;yJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU2e2NlAh[2WubIOgZYZ1\XJiMkSgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEmg{txONg>? NYrTPYtwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkCyNVE2PjRpPkKwNlEyPTZ2PD;hQi=>
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SNB19 Mn;WS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NY\LcmdMPDhiaILz NFPqd21Iem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBUVkJzOTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IEOuPFAyQDlizszNMi=> NEXFN2s9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFIxPCd-MkC4OVAzODR:L3G+
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Hep2 MmTFRY51cWOjbnPldkBie3OjeR?= NWO0enFMPDhiaILz NUDy[3lwSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhmeDJiY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB3cWGkaXzpeJkh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFAvOyEQvF2u MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTB5NES0OEc,OjFyN{S0OFQ9N2F-
A549 M1\VWWFvfGmlYX7j[ZIh[XO|YYm= NVW0blRpPDhiaILz M1LQ[mFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIF{e2W|c3XkJIF{KGOnbHygeoli[mmuaYT5JIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGlEPTBiPTCyMlQh|ryPLh?= NGXyNFY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC3OFQ1PCd-MkGwO|Q1PDR:L3G+
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colon cancer cell NV21RpFwS3m2b4TvfIlkcXS7IHHzd4F6 NHm2SYs1QCCqcoO= M1;V[GN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJINwdG:wIHPhcoNmeiClZXzsd{Bi\nSncjC0PEBpenNiYomgZ492dHSncjDjc5VvfGmwZzygS2k2OCB;IEiuOEDPxE1w NY\EToxRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKwOVYzPzdpPkKyNFU3Ojd5PD;hQi=>
leukemia cell MnKxR5l1d3SxeHnjbZR6KGG|c3H5 M2n6bFQ5KGi{cx?= NWfaPXJHS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hdGW3a3XtbYEh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IHPveYx1\XJiY3;1cpRqdmduIFfJOVAhRSBzNT6xJO69VS5? MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjB3NkK3O{c,OjJyNU[yO|c9N2F-
prostate cancer cell MXjDfZRwfG:6aXPpeJkh[XO|YYm= MnvBOFghcHK| NGXpN|ZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBxem:|dHH0[UBk[W6lZYKgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KGOxdXz0[ZIh[2:3boTpcoctKEeLNUCgQUAzOi55IN88UU4> MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjB3NkK3O{c,OjJyNU[yO|c9N2F-
renal cancer cell Ml3vR5l1d3SxeHnjbZR6KGG|c3H5 M3jj[lQ5KGi{cx?= NXfLd2VzS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hemWwYXygZ4Fv[2W{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBkd3WudHXyJINwfW62aX7nMEBIUTVyIE2gOFUvPiEQvF2u NWPOWplbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKwOVYzPzdpPkKyNFU3Ojd5PD;hQi=>
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MGC803 MnHCRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MorUO|IhcHK| NEXJTHdCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3HR|gxOyClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVYvPiEQvF2u M4jvO|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MEe5N|c5Lz5{MkC3PVM4QDxxYU6=
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HEK293 MlzPR5l1d3SxeHnjbZR6KGG|c3H5 MX:yJIRigXN? M2DqTWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhGUzJ7MzDj[YxteyCjZoTldkAzKGSjeYOgZpkh[WyjbXHyJIJtfWViYYPzZZktKEmFNUCgQUA1Oi57IN88UU4> NW[wboxxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKwPVM4PjFpPkKyNFk{PzZzPD;hQi=>
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leukemia cell M4PJZWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUW0PEBpenN? MVHHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDs[ZVs\W2rYTDj[YxteyCjZoTldkA1QCCqcoOgZpkh[2:3bITldkBkd3WwdHXyJI1mfGixZDygS2k2OCB;IEG1MlEh|ryPLh?= NY\qXIN3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKxNVkyPTFpPkKyNVE6OTVzPD;hQi=>
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H460 MUfDfZRwfG:6aXPpeJkh[XO|YYm= NG[2RXg4OiCqcoO= M4rJeGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGg1PjBiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFMh|ryPLh?= MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjF|MEGzNkc,OjJzM{CxN|I9N2F-
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A549 MVrDfZRwfG:6aXPpeJkh[XO|YYm= NWHHRXZEOjRiaILz MmrzR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bi\nSncjCyOEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOU43PCEQvF2u M1rXV|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MUiyPVI3Lz5{MkG4NlkzPjxxYU6=
QGY7701 MWPDfZRwfG:6aXPpeJkh[XO|YYm= MkDYNlQhcHK| M{DHd2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHFIYTd5MEGgZ4VtdHNiYX\0[ZIhOjRiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF2LkOg{txONg>? NYjCboVHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKxPFI6OjZpPkKyNVgzQTJ4PD;hQi=>
SW480 NU\HRoxPS3m2b4TvfIlkcXS7IHHzd4F6 NYn1OpNuOjRiaILz MVvDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTW|Q5OCClZXzsd{Bi\nSncjCyOEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVUvPzFizszNMi=> MnLQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzOEK5NlYoRjJ{MUiyPVI3RC:jPh?=
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KB NIW1dXFEgXSxdH;4bYNqfHliYYPzZZk> NFvSflY4OiCqcoO= NEPIS2NEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBMSiClZXzsd{Bi\nSncjC3NkBpenNibomgUXRVKGG|c3H5MEBKSzVyIE2gPUDPxE1w MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjJyMESwOEc,OjJ{MEC0NFQ9N2F-
CNE2 NFix[GVEgXSxdH;4bYNqfHliYYPzZZk> NHH3bGs4OiCqcoO= MXfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDUmUzKGOnbHzzJIFnfGW{IEeyJIhzeyCweTDNWHQh[XO|YYmsJGlEPTBiPTCxN{42KM7:TT6= NEC1WZc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkKwNFQxPCd-MkKyNFA1ODR:L3G+
HepG2 M3XQSmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NXy1fokzPDhiaILz NYHlRWM3SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVUvQTJizszNMi=> NFixc|k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkKwPVQ5Pid-MkKyNFk1QDZ:L3G+
NCI-H460 NG\mUINEgXSxdH;4bYNqfHliYYPzZZk> MYDDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDOR2kuUDR4MDDj[YxteyxiSVO1NEA:KDhizszNMi=> MmT0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ{OEO0OVEoRjJ{MkizOFUyRC:jPh?=
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HT1080 M{jQXWN6fG:2b4jpZ4l1gSCjc4PhfS=> MV;DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWFExQDBiY3XscJMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMz6wOkDPxE1w MlraQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6MEG2OFQoRjJ{OECxOlQ1RC:jPh?=
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HT-29 MXnDfZRwfG:6aXPpeJkh[XO|YYm= NHzYVlY4OiCqcoO= M1f6N2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhVNTJ7IHPlcIx{KGGodHXyJFczKGi{czDifUBkenm|dHHsJJZqd2yndDDzeIFqdmmwZzygTWM2OCB;IEeuN{DPxE1w MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjl3OUKwOUc,OjJ7NUmyNFU9N2F-
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colon cancer NGqx[XlCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NWnjfIJQPDhiaILz MX3BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKGOxbH;uJINidmOncjDj[YxteyCjZoTldkA1QCCqcoOgZpkh[2WubDDjc5VvfGmwZzDhcoFtgXOrczygS2k2OCB;IEiuOEDPxE1w NVn3O3hbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5PVU3OjFpPkKyPVk2PjJzPD;hQi=>
leukemia NGXGemRCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= NELldY01QCCqcoO= M3;HRmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5ibHX1b4VucWFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JINmdGxiY3;1cpRqdmdiYX7hcJl{cXNuIFfJOVAhRSBzNT6xJO69VS5? NUfaZXRlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5PVU3OjFpPkKyPVk2PjJzPD;hQi=>
prostate cancer MmD1RY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MWO0PEBpenN? M1LSfWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5icILvd5RifGViY3HuZ4VzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDj[YxtKGOxdX70bY5oKGGwYXz5d4l{NCCJSUWwJF0hOjJwNzFOwG0v Mor3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ7OUW2NlEoRjJ{OUm1OlIyRC:jPh?=
renal cancer NXTLdJl6SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= NYTmd2RxPDhiaILz M3\FXWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5icnXuZYwh[2GwY3XyJINmdGy|IHHmeIVzKDR6IHjyd{BjgSClZXzsJINwfW62aX7nJIFv[Wy7c3nzMEBIUTVyIE2gOFUvPiEQvF2u M2n3flxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OUm1OlIyLz5{Mkm5OVYzOTxxYU6=
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HepG2 M2nWT2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 M1vrWVQ5KGi{cx?= NF\wTIhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjldGczKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQhdWW2aH;kMEBKSzVyIE2gNU4{KM7:TT6= M1\NbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MEG4NFk3Lz5{M{CxPFA6PjxxYU6=
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A549 MnvvR5l1d3SxeHnjbZR6KGG|c3H5 MVe0PEBpenN? M4LNe2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[XO|ZYPz[YQh[2WubDD2bYFjcWyrdImgZYZ1\XJiNEigbJJ{KGK7IGPSRkBie3OjeTygTWM2OCB;IESuNlEh|ryPLh?= MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzB2NEO3NEc,OjNyNESzO|A9N2F-
HT1080 MlTaR5l1d3SxeHnjbZR6KGG|c3H5 M360eVQ5KGi{cx?= MorMR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTHQyODhyIHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyPS5{IN88UU4> MlfCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNyNke1OFkoRjJ|ME[3OVQ6RC:jPh?=
HCT116 NGXEfnVEgXSxdH;4bYNqfHliYYPzZZk> MkXvOFghcHK| NHr0ZW5EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1RzMU[gZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDN4LkSg{txONg>? NXX6U|duRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwOlc2PDlpPkKzNFY4PTR7PD;hQi=>
2008 NICyd2VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFvSWYFIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckAzODB6IHPlcIx{KGK7IHPyfZN1[WxidnnvcIV1KGG|c3H5MEBKSzVyIE2gOE4zKM7:TT6= NX\XdVRCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwO|U1OTRpPkKzNFc2PDF2PD;hQi=>
Vero NUXYXYdbT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlnuS5Jwf3SqIHnubIljcXSrb36gc4Yh[W[{aXPhckBoemWnbjDtc45s\XliVnXyc{Bk\WyuczDifUBkenm|dHHsJJZqd2yndDDhd5NigSxiSVO1NEA:KDRwNTFOwG0v NFS1XHE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{C3OVQyPCd-MkOwO|U1OTR:L3G+
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NIH-H460 NWn1VZJrS3m2b4TvfIlkcXS7IHHzd4F6 Mn7sR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUmlJNUh2NkCgZ4VtdHNiYomgUXRVKG2ndHjv[EwhUUN3MDC9JFcvOTJizszNMi=> NFjieIk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{G2OFcyOCd-MkOxOlQ4OTB:L3G+
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HCT15 M3Txc2N6fG:2b4jpZ4l1gSCjc4PhfS=> NYq3R5JlOjRiaILz NUfFUG5nS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUWgZ4VtdHNiYX\0[ZIhOjRiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDR3LkCxJO69VS5? MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzJyMkS4OEc,OjN{MEK0PFQ9N2F-
MCF7 MnnuR5l1d3SxeHnjbZR6KGG|c3H5 M4O2[FczKGi{cx?= MU\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxO{4zKM7:TT6= MmLMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN{N{m4OlQoRjJ|Mke5PFY1RC:jPh?=
HepG2 MVfDfZRwfG:6aXPpeJkh[XO|YYm= NXLC[Yw2PzJiaILz Mn22R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFIyNjlizszNMi=> M2[5[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|Mke5PFY1Lz5{M{K3PVg3PDxxYU6=
SGC7901 MlHMR5l1d3SxeHnjbZR6KGG|c3H5 MXS3NkBpenN? MYLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTS2M4QTBzIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzQC53IN88UU4> MknMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN{N{m4OlQoRjJ|Mke5PFY1RC:jPh?=
HCT116 MkTBRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MkP4OFghcHK| MYXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEiFVEGxOkBk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKGOnbHygdJJwdGmoZYLheIlwdiCjZoTldkA1QCCqcoOgZpkhW3WuZn;ybI9l[W2rbnWgRkBie3OjeTygTWM2OCB;IEOuOVYh|ryPLh?= NITHVXU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{OwOVkyQSd-MkOzNFU6OTl:L3G+
B16F10 NWDwW3EzSW62aXPhcoNmeiCjc4PhfS=> MlrSOFghcHK| M4Lte2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBud3W|ZTDCNVZHOTBiY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB{fXK4aY\hcEBu\WG|dYLl[EBi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNlEvPDFizszNMi=> NFvlboU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{OxNlk1QSd-MkOzNVI6PDl:L3G+
SGC7901 NF3ySmtCdnSrY3HuZ4VzKGG|c3H5 NEPOUlM1QCCqcoO= MXHBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU1fDO|kxOSClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJN2en[rdnHsJI1m[XO3cnXkJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC0Ok4{PSEQvF2u MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzNzMkm0PUc,OjN|MUK5OFk9N2F-
HeLa MonORY51cXS3bX;yJIF{e2G7 NW\L[YZbPDhiaILz MWXBcpRqfHWvb4KgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKZVzhJINmdGy|IHHzd4V{e2WmIHHzJIdzd3e2aDDpcohq[mm2aX;uJI1m[XO3cnXkJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxOE44QCEQvF2u MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzNzM{[zOUc,OjN|MUO2N|U9N2F-
A549 MknWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlPlOFghcHK| NFnqenRIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA2NjZ2IN88UU4> Ml7nQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN|NUO3N|coRjJ|M{WzO|M4RC:jPh?=
QGY7701 Ml\aS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4PhPFQ5KGi{cx?= NG[3UG1Iem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBST1l5N{CxJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzND6zJO69VS5? NFT1N3E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{O1N|c{Pyd-MkOzOVM4Ozd:L3G+
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HeLa M1PUO2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4fXV|Q5KGi{cx?= MnLVS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVYvOzJizszNMi=> M3roPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|M{WzO|M4Lz5{M{O1N|c{PzxxYU6=
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EC109 NX\FZoM2S3m2b4TvfIlkcXS7IHHzd4F6 MYq3NkBpenN? M4PnUmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGVEOTB7IHPlcIx{KGG|c3Xzd4VlKGG|IHfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB|LkO0JO69VS5? NVzPeXNtRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOzOVM4PDNpPkKzN|U{PzR|PD;hQi=>
MGC803 NYW0[oVVS3m2b4TvfIlkcXS7IHHzd4F6 NHXq[G04OiCqcoO= NWi2e4xjS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUeFOECzJINmdGy|IHHzd4V{e2WmIHHzJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC3MlAyKM7:TT6= NXqzTldiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOzOVM4PDNpPkKzN|U{PzR|PD;hQi=>
MCF7 M1LpVmN6fG:2b4jpZ4l1gSCjc4PhfS=> NGW2PW04OiCqcoO= NIrWdoNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGG|c3Xzd4VlKGG|IHfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB5LkW0JO69VS5? MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzN3M{e0N{c,OjN|NUO3OFM9N2F-
PC3 NEPLPZlEgXSxdH;4bYNqfHliYYPzZZk> M2rpXlczKGi{cx?= MVLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOgZZN{\XO|ZXSgZZMh\3Kxd4ToJIlvcGmkaYTpc44h[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI4NjB5IN88UU4> NYrYVZhERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOzOVM4PDNpPkKzN|U{PzR|PD;hQi=>
colon cancer M4TrfGN6fG:2b4jpZ4l1gSCjc4PhfS=> M4PuelQ5KGi{cx?= MYPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDjc4xwdiClYX7j[ZIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cJBpd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwJF0hQC52IN88UU4> NHv4NVg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{S3OFg6QSd-MkO0O|Q5QTl:L3G+
leukemia NIXUbWlEgXSxdH;4bYNqfHliYYPzZZk> NFvYdVk1QCCqcoO= M1HBZmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJIxmfWunbXnhJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzwbI9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3MDC9JFE2NjFizszNMi=> MnfTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN2N{S4PVkoRjJ|NEe0PFk6RC:jPh?=
prostate cancer NXTP[po6S3m2b4TvfIlkcXS7IHHzd4F6 MWe0PEBpenN? MmDhR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gdJJwe3SjdHWgZ4Fv[2W{IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyyaH;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IEKyMlch|ryPLh?= MknzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN2N{S4PVkoRjJ|NEe0PFk6RC:jPh?=
renal cancer MV7DfZRwfG:6aXPpeJkh[XO|YYm= M{H3NlQ5KGi{cx?= M2HmWWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJJJmdmGuIHPhcoNmeiClZXzsd{Bi\nSncjC0PEBpenNiYomgd5VteGixcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSB2NT62JO69VS5? M1rpRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NEe0PFk6Lz5{M{S3OFg6QTxxYU6=
MCF7 M{jEUmN6fG:2b4jpZ4l1gSCjc4PhfS=> M3rKUlQ5KGi{cx?= MXfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxOk44KM7:TT6= M2nJZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NEmwNVU6Lz5{M{S5NFE2QTxxYU6=
HepG2 M2\OfWN6fG:2b4jpZ4l1gSCjc4PhfS=> NVvl[ZJyPDhiaILz M2XrNGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzOi56IN88UU4> MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzR7MEG1PUc,OjN2OUCxOVk9N2F-
SGC7901 NUTvO286S3m2b4TvfIlkcXS7IHHzd4F6 NXuzZYVSPDhiaILz NEfiO4JEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUT0N5OUCxJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{OD65JO69VS5? NFjsWWQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{S5NFE2QSd-MkO0PVAyPTl:L3G+
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Hep2 Mn\IRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NVuyWFFSPDhiaILz NVzDZ3R{SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[ZAzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCLQ{WwJF0hPC53IN88UU4> M4W4VFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NUCxNVE{Lz5{M{WwNVEyOzxxYU6=
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K562 MWPDfZRwfG:6aXPpeJkh[XO|YYm= NFXUcmQ4OiCqcoO= NWXONGdXS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUzV4MjDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOjhizszNMi=> MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzV|NUOyNkc,OjN3M{WzNlI9N2F-
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A549 NHH6cmREgXSxdH;4bYNqfHliYYPzZZk> MW[0PEBpenN? M1f1dGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFUvPjJizszNMi=> M4TuXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OUKwNlQ3Lz5{M{myNFI1PjxxYU6=
SGC7901 MYLDfZRwfG:6aXPpeJkh[XO|YYm= M1WxcVQ5KGi{cx?= NX;JRmtQS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0eFN{mwNUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iNj6wOEDPxE1w MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl{MEK0Okc,OjN7MkCyOFY9N2F-
MDA-MB-231 MUHDfZRwfG:6aXPpeJkh[XO|YYm= M4rmdVQ5KGi{cx?= MnXHR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWRCNU2ELUKzNUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUOuOlUh|ryPLh?= NF7Odo49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{myNFI1Pid-MkO5NlAzPDZ:L3G+
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HeLa NWfRb3NlS3m2b4TvfIlkcXS7IHHzd4F6 MX60PEBpenN? M{KxZmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE3NjV{IN88UU4> MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl{MEK0Okc,OjN7MkCyOFY9N2F-
A549 MUDDfZRwfG:6aXPpeJkh[XO|YYm= M{fkRVczKGi{cx?= M{TpTmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgO|IhcHK|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFMvPiEQvF2u MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl4NE[3O{c,OjN7NkS2O|c9N2F-
SKOV3 NGizd4JEgXSxdH;4bYNqfHliYYPzZZk> M1jrSVQ5KGi{cx?= NX7xfHVVS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0uRVkOgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ2LkSzJO69VS5? MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl6OEO1O{c,OjN7OEizOVc9N2F-
HepG2 NXPzSWpOS3m2b4TvfIlkcXS7IHHzd4F6 NHHFRnE1QCCqcoO= M37JdGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzQS57ODFOwG0v MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl6OEO1O{c,OjN7OEizOVc9N2F-
A549 NFfvV2pEgXSxdH;4bYNqfHliYYPzZZk> M2j5T|Q5KGi{cx?= NV7ISFVSS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOzRwM{Og{txONg>? M3ToblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OUi4N|U4Lz5{M{m4PFM2PzxxYU6=
NCI-H460 M2jVR2N6fG:2b4jpZ4l1gSCjc4PhfS=> Mon4OFghcHK| MorBR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUmNKNUh2NkCgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDR2LkC0JO69VS5? MnjPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN7OEizOVcoRjJ|OUi4N|U4RC:jPh?=
leukemia M33tOWN6fG:2b4jpZ4l1gSCjc4PhfS=> MUi0PEBpenN? NF;idpVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBt\XWtZX3pZUBk\WyuczDh[pRmeiB2ODDodpMh[nliU2LCJIF{e2G7LDDHTVUxKD1iMT61NUDPxE1w NFflcXI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{m5OFMzQCd-MkO5PVQ{Ojh:L3G+
colon cancer MmHNR5l1d3SxeHnjbZR6KGG|c3H5 NYHWOXV7PDhiaILz NEfLRlVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBkd2yxbjDjZY5k\XJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFgvPCEQvF2u NHjaWVg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{m5OFMzQCd-MkO5PVQ{Ojh:L3G+
prostate cancer Ml3LR5l1d3SxeHnjbZR6KGG|c3H5 NEHvXVQ1QCCqcoO= M{PVNGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJJBzd3O2YYTlJINidmOncjDj[YxteyCjZoTldkA1QCCqcoOgZpkhW1KEIHHzd4F6NCCJSUWwJF0hOjJwNzFOwG0v MlnaQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN7OUSzNlgoRjJ|OUm0N|I5RC:jPh?=
renal cancer M{DZOmN6fG:2b4jpZ4l1gSCjc4PhfS=> NVj4OXZmPDhiaILz M3jvN2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJJJmdmGuIHPhcoNmeiClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBIUTVyIE2gOFUvPiEQvF2u Ml;0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN7OUSzNlgoRjJ|OUm0N|I5RC:jPh?=
A375-S2 M1;MPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{K1TVQ5KGi{cx?= MmPFS5Jwf3SqIHnubIljcXSrb36gZYdicW6|dDDoeY1idiCDM{e1MXMzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC2MlY4KM7:TT6= MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl7OUC0Okc,OjN7OUmwOFY9N2F-
HeLa M372WGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH3YbYI1QCCqcoO= MXrHdo94fGhiaX7obYJqfGmxbjDh[4FqdnO2IHj1cYFvKEinTHGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDdwM{Sg{txONg>? M1zXNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OUm5NFQ3Lz5{M{m5PVA1PjxxYU6=
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MCF7 Ml7kS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXHrNmNLPDhiaILz MYnHdo94fGhiaX7obYJqfGmxbjDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDFzLkWg{txONg>? MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl7OUC0Okc,OjN7OUmwOFY9N2F-
K562 NGr0XWZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MorTOFghcHK| NHHhZVhIem:5dHigbY5pcWKrdHnvckBi\2GrboP0JIh2dWGwIFu1OlIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEKzMlU2KM7:TT6= M2Ps[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OUm5NFQ3Lz5{M{m5PVA1PjxxYU6=
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HCT116 MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHrIXIQ1QCCqcoO= MlPOS5Jwf3SqIHnubIljcXSrb36gZYdicW6|dDDoeY1idiCKQ2SxNVYh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEK3Mlc3KM7:TT6= M1jxXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OUm5NFQ3Lz5{M{m5PVA1PjxxYU6=
HT1080 M1y0[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUfaVmlNPDhiaILz M4TMNGdzd3e2aDDpcohq[mm2aX;uJIFo[Wmwc4SgbJVu[W5iSGSxNFgxKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCzOU43OiEQvF2u M3HEZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OUm5NFQ3Lz5{M{m5PVA1PjxxYU6=
HepG2 M3O2TWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2W3OlQ5KGi{cx?= NEnTOIhIem:5dHigbY5pcWKrdHnvckBi\2GrboP0JIh2dWGwIFjldGczKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC0NE4{PCEQvF2u Mm\nQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN7OUmwOFYoRjJ|OUm5NFQ3RC:jPh?=
A549 NITGSoRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3vzO|Q5KGi{cx?= MnXrS5Jwf3SqIHnubIljcXSrb36gZYdicW6|dDDoeY1idiCDNUS5JINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB2ND6wOUDPxE1w NF36cGc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{m5PVA1Pid-MkO5PVkxPDZ:L3G+
QSG7701 M4LVWmN6fG:2b4jpZ4l1gSCjc4PhfS=> NHe5d2M1QCCqcoO= M2nGPGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHFUTzd5MEGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KEOFSz24JIF{e2G7LDDJR|UxKD1iMD62JO69VS5? MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDBzM{SxOUc,OjRyMUO0NVU9N2F-
HepG2 M2X6W2N6fG:2b4jpZ4l1gSCjc4PhfS=> MWC0PEBpenN? NWTFbXlUS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KEOFSz24JIF{e2G7LDDJR|UxKD1iMUKuOFgh|ryPLh?= M3HaOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MEGzOFE2Lz5{NECxN|QyPTxxYU6=
SMMC7721 NVq1TFBlS3m2b4TvfIlkcXS7IHHzd4F6 NXn5b|cxPDhiaILz NVLKdodNS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW02PQ{e3NlEh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IFPDT{05KGG|c3H5MEBKSzVyIE2gNVQvPTVizszNMi=> M{nvcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MEGzOFE2Lz5{NECxN|QyPTxxYU6=
QGY7703 MlznR5l1d3SxeHnjbZR6KGG|c3H5 NXzofHlPPDhiaILz MV;DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDRS3k4PzB|IHPlcIx{KGGodHXyJFQ5KGi{czDifUBES0tvODDhd5NigSxiSVO1NEA:KDF3Lk[2JO69VS5? NHXmXFc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NECxN|QyPSd-MkSwNVM1OTV:L3G+
Hep MmjiR5l1d3SxeHnjbZR6KGG|c3H5 M3nN[lQ5KGi{cx?= Mmi5R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGlEPTBiPTCwMlUh|ryPLh?= M3X1SVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MEW2NVQ3Lz5{NEC1OlE1PjxxYU6=
IMR32 M2L2fWN6fG:2b4jpZ4l1gSCjc4PhfS=> M1HCe|Q5KGi{cx?= MX;DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDJUXI{OiClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG|c3H5MEBKSzVyIE2gNU4{KM7:TT6= MnzQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyNU[xOFYoRjJ2MEW2NVQ3RC:jPh?=
A549 NHXheo1EgXSxdH;4bYNqfHliYYPzZZk> MWCyOEBpenN? NX;INFJUS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkAzPCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOS5zIN88UU4> MmPzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyNkC0PFYoRjJ2ME[wOFg3RC:jPh?=
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