Dactolisib (BEZ235)

For research use only. Not for use in humans.

目录号:S1009 别名: NVP-BEZ235

Dactolisib (BEZ235) Chemical Structure

CAS No. 915019-65-7

Dactolisib (BEZ235, NVP-BEZ235) 是一种双重ATP竞争性 PI3KmTOR 抑制剂,在无细胞试验中,抑制 p110α/γ/δ/β 和 mTOR(p70S6K) 的 IC50 分别为 4 nM /5 nM /7 nM /75 nM /6 nM。 在 3T3TopBP1-ER 细胞中抑制 ATR,IC50 为 21 nM,而对 Akt 和 PDK1 的抑制作用很弱。Dactolisib可诱导自噬并抑制HIV-1的复制。Phase 2。

规格 价格 库存 购买数量  
RMB 895.88 现货
RMB 1414.41 现货
有超大折扣

今日订购,明日送达,全国免运费!

全国免费电话:400-668-6834   |   Email:info@selleck.cn

客户使用Selleck生产的Dactolisib (BEZ235)发表文献315篇:

产品安全说明书

PI3K抑制剂选择性比较

生物活性

产品描述 Dactolisib (BEZ235, NVP-BEZ235) 是一种双重ATP竞争性 PI3KmTOR 抑制剂,在无细胞试验中,抑制 p110α/γ/δ/β 和 mTOR(p70S6K) 的 IC50 分别为 4 nM /5 nM /7 nM /75 nM /6 nM。 在 3T3TopBP1-ER 细胞中抑制 ATR,IC50 为 21 nM,而对 Akt 和 PDK1 的抑制作用很弱。Dactolisib可诱导自噬并抑制HIV-1的复制。Phase 2。
靶点
p110α [1]
(Cell-free assay)
p110γ [1]
(Cell-free assay)
mTOR (p70S6K) [1]
(Cell-free assay)
p110δ [1]
(Cell-free assay)
ATR [8]
(3T3TopBP1-ER cells)
4 nM 5 nM 6 nM 7 nM 21 nM
体外研究

BEZ235显著降低mTOR活化的激酶p70S6K的磷酸化水平。BEZ235导致S235/S236P-RPS6水平减少,IC50为6.5 nM。BEZ235抗mTOR的活性使用生化mTOR K-LISA试验测定,IC50为20.7 nM。BEZ235对其β旁系同源物的活性稍弱,IC50为75 nM。在人肿瘤细胞中,PI3K/Akt/mTOR通路经常被组成性活化。BEZ235阻断PI3K和mTOR激酶活性,通过结合于这些酶的ATP结合槽发挥作用。用逐渐增加浓度BEZ235处理PTEN-null细胞系PC3M和U87MG时,导致细胞增殖剂量依赖性减少,平均GI50为10-12 nM。[1] BEZ235是一种mTORC1/2催化抑制剂。[2]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
Trypanosoma brucei brucei NYnWNXRTSW62aX3pZ5Jw[mmjbDDBd5NigQ>? MlL0NVghcA>? M4PWfGROW09? MojKRY51cXS{eYDhco9{d22jbDDhZ5Rqfmm2eTD3bZRpKEWFNUCgc4YhOC5yMEK1JO69VQ>? NYrOZZVnOjR6MEW5OFY>
MCF7 NH\JPJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlfxNE4xOS1zMECg{txO NHiyZZY1QCCq MXTEUXNQ MmDnTWM2OD1yLkezJO69VQ>? Mn7VNlM5PzF7MES=
HCT116 Mn7vS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV:wMlAyNTFyMDFOwG0> MVy0PEBp NGPueI5FVVOR NWrFUnROUUN3ME2xMlE3KM7:TR?= NUjGWlZjOjN6N{G5NFQ>
U87MG Mmm2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXuwMlAyNTFyMDFOwG0> MXW0PEBp MVXEUXNQ MlzVTWM2OD1zLkOyJO69VQ>? MkTnNlM5PzF7MES=
HBC4 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmLTNE4xOS1zMECg{txO MkjHOFghcA>? MmTvUI9oKEeLNUC9MVgvPjFiTR?= MVSyNlM{PjJ2Nh?=
BSY1 NYjs[JZFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHL5XVAxNjBzLUGwNEDPxE1? M2ftXVQ5KGh? NETpd4tNd2diR1m1NF0uQC52ODDN MlLQNlI{OzZ{NE[=
HBC5 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoDmNE4xOS1zMECg{txO MX20PEBp NGXxRYlNd2diR1m1NF0uPy56NzDN NYHVepR2OjJ|M{[yOFY>
MCF7 NFezXpVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYmwMlAyNTFyMDFOwG0> MUi0PEBp NUDGUpo6VG:pIFfJOVA:NThwMU[gUS=> MVyyNlM{PjJ2Nh?=
MDA-MB-231 NILCXm5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2HUUlAvODFvMUCwJO69VQ>? NILhcWo1QCCq MnH4UI9oKEeLNUC9MVgvODliTR?= NVztd4EzOjJ|M{[yOFY>
U251 MlLKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGW3foMxNjBzLUGwNEDPxE1? Ml3vOFghcA>? M1XtZmxw\yCJSUWwQU04NjZ4IF2= MmixNlI{OzZ{NE[=
SF268 MkS3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{HsXlAvODFvMUCwJO69VQ>? M4HpRVQ5KGh? Mn3uUI9oKEeLNUC9MVcvQTJiTR?= M2rFUFIzOzN4MkS2
SF295 Mn3SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1jSXlAvODFvMUCwJO69VQ>? NFvQTo81QCCq MkLyUI9oKEeLNUC9MVgvOzFiTR?= NWDSUYZROjJ|M{[yOFY>
SF539 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV[wMlAyNTFyMDFOwG0> M4fxUFQ5KGh? NVjaS3RqVG:pIFfJOVA:NThwNUmgUS=> MlixNlI{OzZ{NE[=
SNB75 MnO0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoHoNE4xOS1zMECg{txO MXm0PEBp NIXkSItNd2diR1m1NF0uQC53ODDN NInLPGwzOjN|NkK0Oi=>
SNB78 NVfBfpduT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFn0U2ExNjBzLUGwNEDPxE1? NILIWpo1QCCq NXG4c40xVG:pIFfJOVA:NThwNkWgUS=> NInCbnQzOjN|NkK0Oi=>
HCC2998 NH;md4JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIjVflExNjBzLUGwNEDPxE1? M4PNflQ5KGh? M2rUWWxw\yCJSUWwQU05NjB3IF2= MW[yNlM{PjJ2Nh?=
KM12 MojwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1rXe|AvODFvMUCwJO69VQ>? NHT6PG41QCCq NVnrOGFKVG:pIFfJOVA:NTdwNUSgUS=> M{HrZlIzOzN4MkS2
HT-29 MkXwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkTPNE4xOS1zMECg{txO NVzNNGhqPDhiaB?= MU\Mc4chT0l3ME2tO{44PSCP MWCyNlM{PjJ2Nh?=
HCT15 MmO5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF\uZ|kxNjBzLUGwNEDPxE1? MWO0PEBp NUfrepJnVG:pIFfJOVA:NThwMEOgUS=> NULKXm9HOjJ|M{[yOFY>
HCT116 M{L1S2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVmzNXQzOC5yMT2xNFAh|ryP NEPVd4Y1QCCq NFzGfWNNd2diR1m1NF0uPy54MTDN NWTXR5RLOjJ|M{[yOFY>
NCI-H23 MkizS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEfzN2IxNjBzLUGwNEDPxE1? NFrMbmM1QCCq M2nFWmxw\yCJSUWwQU04NjZ2IF2= NVLEUW5pOjJ|M{[yOFY>
NCI-H226 MnvTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4HsZ|AvODFvMUCwJO69VQ>? M2ftTFQ5KGh? Mle1UI9oKEeLNUC9MVgvPDRiTR?= Mm[xNlI{OzZ{NE[=
NCI-H522 M{DYZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVmwMlAyNTFyMDFOwG0> M3rwWFQ5KGh? MkD6UI9oKEeLNUC9MVgvPDViTR?= NXnXd|NwOjJ|M{[yOFY>
NCI-H438 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MonLNE4xOS1zMECg{txO M4HLV|Q5KGh? NX3zVmZ1VG:pIFfJOVA:NThwMUGgUS=> MWqyNlM{PjJ2Nh?=
A549 NYLMO2JET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3jxb|AvODFvMUCwJO69VQ>? M3zlfVQ5KGh? NEi5Tm1Nd2diR1m1NF0uQC5yNzDN MVGyNlM{PjJ2Nh?=
DMS273 MmThS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYe1dGFNOC5yMT2xNFAh|ryP M3;EdFQ5KGh? NFTu[|BNd2diR1m1NF0uPy56MDDN NYmwdJR4OjJ|M{[yOFY>
DMS114 NWTPVGRZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGrGZmUxNjBzLUGwNEDPxE1? NWT0N|BRPDhiaB?= MVLMc4chT0l3ME2tPE4{QSCP MmDQNlI{OzZ{NE[=
LOXIMVI MmS4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NU\oVZZQOC5yMT2xNFAh|ryP NHnrdI01QCCq NGfrUZlNd2diR1m1NF0uQC54NjDN NXrtOFB2OjJ|M{[yOFY>
OVCAR3 NEP3PWlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWL2UWJYOC5yMT2xNFAh|ryP NXXKbYVzPDhiaB?= MkTUUI9oKEeLNUC9MVgvOTdiTR?= MorVNlI{OzZ{NE[=
OVCAR4 Ml;MS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHzZZmMxNjBzLUGwNEDPxE1? MUe0PEBp MV\Mc4chT0l3ME2tPE42QCCP M1PsblIzOzN4MkS2
OVCAR5 NUDLOXlpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXzEU5lROC5yMT2xNFAh|ryP M3HuWFQ5KGh? MVTMc4chT0l3ME2tO{42PyCP MXWyNlM{PjJ2Nh?=
OVCAR8 NVn6WYN5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1vXOFAvODFvMUCwJO69VQ>? NYPncWtRPDhiaB?= MVXMc4chT0l3ME2tO{45PCCP M3rzeFIzOzN4MkS2
SKOV3 MkTXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWPwS2pEOC5yMT2xNFAh|ryP NEjEPWU1QCCq MoTWUI9oKEeLNUC9MVgvPDFiTR?= MlXhNlI{OzZ{NE[=
RXF631L MnL6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmH0NE4xOS1zMECg{txO MnTqOFghcA>? MVnMc4chT0l3ME2tPE4zOSCP M4H0NFIzOzN4MkS2
ACHN NX3LcZNsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF;nTGoxNjBzLUGwNEDPxE1? MnS1OFghcA>? NUH1SWZDVG:pIFfJOVA:NTdwOUWgUS=> MXuyNlM{PjJ2Nh?=
St-4 NVv3Smx{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYKwMlAyNTFyMDFOwG0> MoPQOFghcA>? MXPMc4chT0l3ME2tO{41PyCP NWDYV5ZwOjJ|M{[yOFY>
MKN1 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3vr[VAvODFvMUCwJO69VQ>? NFfDb4c1QCCq MkTPUI9oKEeLNUC9MVgvPDFiTR?= M3f4VVIzOzN4MkS2
MKN7 NEG2NWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MViwMlAyNTFyMDFOwG0> MnPJOFghcA>? NWPxUGs5VG:pIFfJOVA:NTdwNkigUS=> Mn;1NlI{OzZ{NE[=
MKN28 NXjKNodpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVOwMlAyNTFyMDFOwG0> NFe5bm81QCCq MVPMc4chT0l3ME2tO{4xPyCP MW[yNlM{PjJ2Nh?=
MKN45 MkD4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkLQNE4xOS1zMECg{txO NYHuWG9[PDhiaB?= M2XKbWxw\yCJSUWwQU05NjN2IF2= MV2yNlM{PjJ2Nh?=
MKN74 NV7zVZY4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV\RVVc4OC5yMT2xNFAh|ryP MXK0PEBp NV;RelQ4VG:pIFfJOVA:NTdwNEKgUS=> NFjM[IEzOjN|NkK0Oi=>
DU145 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M324[FAvODFvMUCwJO69VQ>? M4fWTVQ5KGh? M2PTO2xw\yCJSUWwQU05NjF4IF2= NX7Ffo9xOjJ|M{[yOFY>
PC3 M1i2[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWG4S5pUOC5yMT2xNFAh|ryP NWPBXJdGPDhiaB?= M2G0U2xw\yCJSUWwQU05NjZ4IF2= M2PuOlIzOzN4MkS2
Trypanosoma brucei brucei NIC1ZpRHfW6ldHnvckBCe3OjeR?= MWWyNFAhdk1? NHvIR|UyOiCq NHnVOWtFVVOR NWXDXItlTGWlcnXhd4UhcW5icHjvd5Bpd3SrZInsJIlvd3OrdH;sJJBpd3OyaHH0[UBt\X[nbB?= NGPPZVMzPDhyNUm0Oi=>
Trypanosoma brucei brucei MYTGeY5kfGmxbjDBd5NigQ>? NHTRXZkyQCCq Mme1SG1UVw>? M1rufWlvcGmkaYTpc44hd2ZicnXj[ZB1d3JvbXXkbYF1\WRiZX7kc4N6fG:|aYOgZZN{\XO|ZXSgZZMh\GWlcnXhd4UhcW5idILhcpNn\XK{aX6geZB1[Wun MnPkNlQ5ODV7NE[=
Trypanosoma brucei brucei M1jwbWZ2dmO2aX;uJGF{e2G7 NIS4cnozODBibl2= MX6xNkBp NF35SJJFVVOR MUPF[oZm[3Rib36gd5BpcW6pb335cIVqdiCuZY\lcC=> NIPyU|IzPDhyNUm0Oi=>
Trypanosoma brucei brucei NUHoeY9sTnWwY4Tpc44hSXO|YYm= NV;2Snk1OjByIH7N MVexNkBp NXvndYwxTE2VTx?= MXnF[oZm[3Rib36gdIhwe3CqYYTp[Jlt[2ixbHnu[UBt\X[nbB?= NIPtTVIzPDhyNUm0Oi=>
UM-UC-3 NH7zbGZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mm\lTWM2OD1|MUWgdG0> MkPuV2FPT0WU
SBC-1 NXjyUGZvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYDPOoxKUUN3ME23OFIheE1? NF3MbWJUSU6JRWK=
MKN1 NUj2WWQzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mmi2TWM2OD1{Lkigcm0> M2f0WXNCVkeHUh?=
NCI-H720 M4DVeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkfWTWM2OD1|LkW3JI5O NF7Fd5pUSU6JRWK=
BFTC-909 NVi1UWlIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUXKUWFDUUN3ME2zMlcyKG6P NX7TfHVOW0GQR1XS
BPH-1 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2HYPWlEPTB;ND63OkBvVQ>? MXPTRW5ITVJ?
PC-3 M4K5cGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4jzNWlEPTB;NT6wPUBvVQ>? M3vKPXNCVkeHUh?=
AN3-CA MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NILPSHhKSzVyPUWuOVYhdk1? MXjTRW5ITVJ?
HN MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVHJR|UxRTVwOU[gcm0> NWLKZoFqW0GQR1XS
HCC2218 M{HXfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHjjWItKSzVyPU[uOlEhdk1? M2rXR3NCVkeHUh?=
KP-4 Mly3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWrJR|UxRTdibl2= MX;TRW5ITVJ?
LU-139 M3m0d2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFzkc5hKSzVyPUeuO|chdk1? MUDTRW5ITVJ?
ETK-1 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4njfWlEPTB;Nz64PEBvVQ>? MY\TRW5ITVJ?
Ramos-2G6-4C10 M{XENGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGm5N5JKSzVyPUiuOFkhdk1? MVfTRW5ITVJ?
MHH-PREB-1 M1\scmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYfJR|UxRTlwMUKgcm0> M3\XcHNCVkeHUh?=
DU-4475 NUjJR|JHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVy4dVBRUUN3ME25MlQ1KG6P NYm0VY92W0GQR1XS
NCI-H1666 NWLvTINCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYXJR|UxRTlwN{Ggcm0> MlzPV2FPT0WU
CAMA-1 MkHrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{LKZ2lEPTB;OT64JI5O M2WyZ3NCVkeHUh?=
TYK-nu MmToS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVThWINkUUN3ME25Mlk1KG6P MXTTRW5ITVJ?
MFE-280 MnH1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MknZTWM2OD17Lkm5JI5O MY\TRW5ITVJ?
A549 M2HMN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVXJR|UxRTFyLkG0JI5O NIn6fXVUSU6JRWK=
769-P NGL3cWJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX;0UoxIUUN3ME2xNE41PCCwTR?= M3jwe3NCVkeHUh?=
L-363 Mn3US5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH\idG9KSzVyPUGwMlY6KG6P MVjTRW5ITVJ?
ES8 MnzJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV7JR|UxRTFyLkmgcm0> MnfTV2FPT0WU
PA-1 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmDrTWM2OD1zMT64NkBvVQ>? NV7nU3c1W0GQR1XS
Mewo NIPsUmRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVjJR|UxRTFzLkm5JI5O NV3WN3hCW0GQR1XS
HSC-3 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGrpRmRKSzVyPUGyMlIyKG6P NXvEXVhTW0GQR1XS
H4 M4rCXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUPJR|UxRTF{Lk[3JI5O NVi5fop1W0GQR1XS
BB65-RCC MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1S2emlEPTB;MUKuO|Ihdk1? M3\TfHNCVkeHUh?=
NCI-H1793 M{fQVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2TQOWlEPTB;MUKuPFIhdk1? MmfVV2FPT0WU
KARPAS-45 M4\XN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mlz1TWM2OD1zMz61NUBvVQ>? M1HTcHNCVkeHUh?=
GCT MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXXJR|UxRTF|Lk[4JI5O NULTNoh1W0GQR1XS
EoL-1 NVXKPYU{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXLEfG1XUUN3ME2xN{46OyCwTR?= NHi3R2FUSU6JRWK=
LB2241-RCC MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXjJR|UxRTF2LkCxJI5O M{n2N3NCVkeHUh?=
ES5 M1HDOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYPJR|UxRTF2Lke0JI5O MWPTRW5ITVJ?
LOXIMVI NUGzWIJWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVXJR|UxRTF2Lkm5JI5O M3Xjc3NCVkeHUh?=
COR-L105 NH3he21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGqzRWpKSzVyPUG1MlA1KG6P M1P0RXNCVkeHUh?=
P12-ICHIKAWA NIXDfVFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2HnOGlEPTB;MUWuNUBvVQ>? NYW4fmMxW0GQR1XS
CHL-1 MlvvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEf5bJBKSzVyPUG1MlQ2KG6P MX;TRW5ITVJ?
VMRC-RCZ M2SxOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MojlTWM2OD1zNT62N{BvVQ>? MnWyV2FPT0WU
HH MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVjJR|UxRTF3Lkegcm0> M2XjXHNCVkeHUh?=
NUGC-3 NX64bYZRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVjJR|UxRTF4LkO0JI5O MoXBV2FPT0WU
EGI-1 MkXpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmnNTWM2OD1zNj60N{BvVQ>? MnHIV2FPT0WU
OS-RC-2 NXTnbZhRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmLDTWM2OD1zNj60O{BvVQ>? NYXzNGtlW0GQR1XS
MOLT-16 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV3JR|UxRTF5LkG1JI5O M2X2dHNCVkeHUh?=
NCI-H209 MmSyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoXNTWM2OD1zNz6yPUBvVQ>? M3zOdnNCVkeHUh?=
697 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWWzOo43UUN3ME2xO{41OyCwTR?= NUjtOWg1W0GQR1XS
D-56MG NGPKT3BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIXhZWpKSzVyPUG3MlY6KG6P MXfTRW5ITVJ?
VA-ES-BJ MoPWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1zqW2lEPTB;MUeuPFMhdk1? NEL0OGFUSU6JRWK=
EW-16 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1LDRmlEPTB;MUiuNFQhdk1? NG\1[JBUSU6JRWK=
HGC-27 NI[0fXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVPJR|UxRTF6LkC2JI5O M2L6S3NCVkeHUh?=
ES7 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHjB[mJKSzVyPUG4MlA6KG6P Mn3KV2FPT0WU
HuH-7 M375cGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2juT2lEPTB;MUiuOEBvVQ>? MX\TRW5ITVJ?
BCPAP MlvRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnjhTWM2OD1zOD62OUBvVQ>? NUnXe3U4W0GQR1XS
SW1710 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1S2[GlEPTB;MUiuO|Ihdk1? M33PdHNCVkeHUh?=
IST-MEL1 NIrUO2pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mlu0TWM2OD1zOD63O{BvVQ>? NH3OfIlUSU6JRWK=
SF295 NFvaU3dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MW\JR|UxRTF6LkmzJI5O NGq0U4JUSU6JRWK=
RPMI-7951 NGXPbIhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmHiTWM2OD1zOT6yPEBvVQ>? MoK0V2FPT0WU
SF126 M4jSOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXHJR|UxRTF7LkSxJI5O MU\TRW5ITVJ?
GAMG M124bmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3nMR2lEPTB;MUmuOFghdk1? M{f0VXNCVkeHUh?=
KNS-81-FD MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmGzTWM2OD1zOT61OEBvVQ>? M37BVHNCVkeHUh?=
RT-112 M1XwWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVXJR|UxRTF7Lk[2JI5O NWL5dWtVW0GQR1XS
DEL M3PIbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1zkVGlEPTB;MkCuOFkhdk1? MnLlV2FPT0WU
CGTH-W-1 NHrwcFBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHS2XIhKSzVyPUKwMlY{KG6P NECxTlRUSU6JRWK=
HOS MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M13rTGlEPTB;MkGuNFYhdk1? NUjqfGNPW0GQR1XS
ES4 NGHIbHJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX3JR|UxRTJzLkC4JI5O MXnTRW5ITVJ?
RXF393 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHXrfYpKSzVyPUKxMlQ2KG6P MV7TRW5ITVJ?
NCI-H2030 MnP0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGm1[lZKSzVyPUKxMlUzKG6P NYDlU|F1W0GQR1XS
YH-13 NHrFZ|ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVS1U3ZUUUN3ME2yNU45QCCwTR?= MWjTRW5ITVJ?
HT-1080 MnjCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWLseIZ4UUN3ME2yNU46OyCwTR?= NG\6UWlUSU6JRWK=
NCI-SNU-1 NFjRWmlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NG\oVpdKSzVyPUKxMlk2KG6P NYrVfXBoW0GQR1XS
G-402 M4myRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn3hTWM2OD1{Mj6xOkBvVQ>? NXnqXWYzW0GQR1XS
786-0 NVPiUYxHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWTWXmxmUUN3ME2yNk4zQSCwTR?= MXTTRW5ITVJ?
ME-180 M1nse2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2\lcWlEPTB;MkKuOFMhdk1? NYfvW|RGW0GQR1XS
NB69 M4\nXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFXneoxKSzVyPUKyMlU{KG6P MV3TRW5ITVJ?
J-RT3-T3-5 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHrG[FRKSzVyPUKyMlk3KG6P NIrTcI9USU6JRWK=
TGBC1TKB MkDPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTJ|LkC1JI5O M4ruT3NCVkeHUh?=
SW780 M{jpOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn7TTWM2OD1{Mz6xN{BvVQ>? MYDTRW5ITVJ?
MG-63 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVPl[WdVUUN3ME2yN{41PSCwTR?= M32xb3NCVkeHUh?=
BV-173 MmH5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWLJR|UxRTJ|Lki3JI5O Ml3tV2FPT0WU
CAL-51 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX3JR|UxRTJ|Lki5JI5O NESyfWdUSU6JRWK=
A375 Ml7ES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIHsUmhKSzVyPUKzMlk{KG6P MnLRV2FPT0WU
MEL-HO NH;iZWJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYq2eYt2UUN3ME2yOE4xPCCwTR?= NH7sc2lUSU6JRWK=
EFO-27 MnLQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MULJR|UxRTJ2LkOzJI5O NWfFNVRuW0GQR1XS
Hs-578-T M1rx[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUTJR|UxRTJ2LkW4JI5O MWHTRW5ITVJ?
NBsusSR M1ryTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVLJR|UxRTJ2Lk[gcm0> NIrycphUSU6JRWK=
CTB-1 MmTIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYjJR|UxRTJ2Lk[3JI5O NWTSe5lsW0GQR1XS
FTC-133 M{K0cWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGTrUpdKSzVyPUK1MlEhdk1? MV7TRW5ITVJ?
MOLT-4 NV7hXlZxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnfaTWM2OD1{NT6xNkBvVQ>? MljlV2FPT0WU
HO-1-N-1 M4P3OGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVz1OXJnUUN3ME2yOU4yPSCwTR?= MoizV2FPT0WU
ES3 M2i5Omdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIXGcpFKSzVyPUK1MlIzKG6P MmHWV2FPT0WU
TI-73 MkTiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml3lTWM2OD1{NT6yPEBvVQ>? MWnTRW5ITVJ?
MPP-89 NI\JXZZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkPXTWM2OD1{NT6zNkBvVQ>? M{DoOXNCVkeHUh?=
KYSE-150 NFK2UVhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUjJR|UxRTJ3Lki5JI5O NFT5dpBUSU6JRWK=
LXF-289 MnPHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUnJR|UxRTJ4LkC0JI5O MmDJV2FPT0WU
SK-LU-1 NFWwbpNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2W1XGlEPTB;Mk[uNVchdk1? M2DOd3NCVkeHUh?=
HOP-92 M2T5WWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWDJR|UxRTJ4LkS4JI5O MnfYV2FPT0WU
HuO9 NES3e4pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXzJR|UxRTJ4Lke2JI5O Mkf0V2FPT0WU
SW962 MkPOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MorDTWM2OD1{Nj63OkBvVQ>? MoC1V2FPT0WU
RS4-11 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoPwTWM2OD1{Nj65NUBvVQ>? NVvj[5MyW0GQR1XS
NCI-H292 NEfJc4JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGHmXpVKSzVyPUK3JI5O NIHpfmVUSU6JRWK=
DB NXLyPWlLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3raRmlEPTB;MkeuN|Yhdk1? NITCN|dUSU6JRWK=
SW1088 M3O4WWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWjJR|UxRTJ6LkK5JI5O NITFT4VUSU6JRWK=
A204 M1W2Nmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIPJcGxKSzVyPUK4MlQ4KG6P NIG0TmRUSU6JRWK=
A3-KAW MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1Lv[WlEPTB;MkiuOlQhdk1? M4fwOnNCVkeHUh?=
MV-4-11 NXXON2tpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVXJbWFUUUN3ME2yPE44KG6P NXPYRoVbW0GQR1XS
ES1 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHu1SnJKSzVyPUK4Mlg1KG6P NIH3U2FUSU6JRWK=
ONS-76 Mk[zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGm0OnBKSzVyPUK5MlA2KG6P NH7RTGhUSU6JRWK=
D-263MG MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{PSZ2lEPTB;MkmuN|Uhdk1? NWXIOHVmW0GQR1XS
U-2-OS Mly5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVzZNmcxUUN3ME2yPU42KG6P NWnNcVd1W0GQR1XS
T98G MlrZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGfrbo5KSzVyPUK5Mlg5KG6P NYrQcmx3W0GQR1XS
GI-ME-N NVrKWm1NT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1PES2lEPTB;MkmuPVEhdk1? NEXifnVUSU6JRWK=
BHT-101 NWP2OXJmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnHXTWM2OD1|MD6wOUBvVQ>? NEXkbJpUSU6JRWK=
NOS-1 NX3TUpNuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVTTbpB{UUN3ME2zNE4yOiCwTR?= M4f1VHNCVkeHUh?=
AsPC-1 Mlr4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXrwNI1kUUN3ME2zNE4zKG6P M{fYSXNCVkeHUh?=
QIMR-WIL M1;UPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml\JTWM2OD1|MD62JI5O MWDTRW5ITVJ?
JVM-3 MlLuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFr4[pNKSzVyPUOwMlg{KG6P NIPZZWZUSU6JRWK=
KU-19-19 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnvpTWM2OD1|MT6xN{BvVQ>? NH\hZZJUSU6JRWK=
OVCAR-8 NX3OfFFbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWH1N3h3UUN3ME2zNU4zPiCwTR?= NITv[VlUSU6JRWK=
BEN MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnzuTWM2OD1|MT62N{BvVQ>? NXvnNHAzW0GQR1XS
BE-13 NHqzeXpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYD4OmJ1UUN3ME2zNU45OiCwTR?= NUXLN5lMW0GQR1XS
EW-18 MkHjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTNzLki2JI5O NYXkeohbW0GQR1XS
ECC10 M{n6Zmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3rFTWlEPTB;M{GuPVUhdk1? MUHTRW5ITVJ?
CTV-1 MmjUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWjJR|UxRTN{LkiyJI5O M3XpRXNCVkeHUh?=
COLO-800 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2TnWWlEPTB;M{KuPVIhdk1? M1H1UnNCVkeHUh?=
A2058 M2nUbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFS2XnRKSzVyPUOzMlI2KG6P NEDkWJlUSU6JRWK=
VM-CUB-1 M{DOd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkjRTWM2OD1|Mz60N{BvVQ>? MX3TRW5ITVJ?
Ca9-22 NGLnVYFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NU\4dllXUUN3ME2zN{42PSCwTR?= NFvaPYFUSU6JRWK=
COLO-684 M{P5fWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NILScnJKSzVyPUOzMlU5KG6P MXTTRW5ITVJ?
RPMI-8226 NYnZOYpxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXj6[oZXUUN3ME2zN{45OiCwTR?= M3PabnNCVkeHUh?=
SK-NEP-1 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M37vRmlEPTB;M{SuNVUhdk1? NXHPUXlyW0GQR1XS
Becker NH7KeVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXrJR|UxRTN2LkKxJI5O MlHVV2FPT0WU
NCI-H28 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFfic3BKSzVyPUO0MlQ1KG6P NU\vT4c5W0GQR1XS
CAL-120 NYXEV4VKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkX5TWM2OD1|ND63NkBvVQ>? NWHYcmxuW0GQR1XS
MDA-MB-157 MnjlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWLCU5FxUUN3ME2zOU41OSCwTR?= M1PDWHNCVkeHUh?=
OVCAR-5 NX3y[JM5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1zocmlEPTB;M{WuOFchdk1? NEWzboZUSU6JRWK=
LAMA-84 NV3iXW9nT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF;2c4JKSzVyPUO1Mlg4KG6P NHGzVGlUSU6JRWK=
CAKI-1 MnjrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV\HcXBtUUN3ME2zOk41OyCwTR?= MknDV2FPT0WU
Daoy M1PxXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYrJR|UxRTN4Lkegcm0> NEPTW4JUSU6JRWK=
CAL-62 NFnwSHZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUSyWllLUUN3ME2zOk45PiCwTR?= MnjEV2FPT0WU
8-MG-BA NUfOfYhUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2r0[mlEPTB;M{euNlUhdk1? NULnTmhXW0GQR1XS
8505C NF\0eotIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmjvTWM2OD1|Nz61NUBvVQ>? MWPTRW5ITVJ?
LNCaP-Clone-FGC MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUSxPXpRUUN3ME2zO{42QSCwTR?= NH32THBUSU6JRWK=
CAL-39 MnLvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVLJR|UxRTN5Lkmgcm0> M17Sb3NCVkeHUh?=
MN-60 NFPNS3lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4f1V2lEPTB;M{euPVYhdk1? NWTIT|FpW0GQR1XS
RKO NIr2[oVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2fKNWlEPTB;M{iuN|Mhdk1? MkfEV2FPT0WU
U251 NEjwS3RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXr2NFJEUUN3ME2zPE41OyCwTR?= M3m1SnNCVkeHUh?=
SJSA-1 M2nyfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWrVSnRSUUN3ME2zPE42PCCwTR?= MkDhV2FPT0WU
CAL-12T MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmH5TWM2OD1|OD62JI5O MXTTRW5ITVJ?
HCC1419 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUnJR|UxRTN6LkexJI5O NX7tXolyW0GQR1XS
CO-314 NI\lfYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MorkTWM2OD1|OD63OEBvVQ>? NE[4RYZUSU6JRWK=
LB1047-RCC NE\FflJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWDXXplmUUN3ME2zPE45OSCwTR?= MkPiV2FPT0WU
A101D NGTldW1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{XsVWlEPTB;M{iuPVchdk1? M2foeXNCVkeHUh?=
MDA-MB-175-VII M33BU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlPOTWM2OD1|OT61NUBvVQ>? MmjhV2FPT0WU
MZ2-MEL MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmTJTWM2OD1|OT62OkBvVQ>? MXTTRW5ITVJ?
NB5 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{WzZWlEPTB;NECuOlQhdk1? MW\TRW5ITVJ?
G-401 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1nUWmlEPTB;NECuPFIhdk1? MoPFV2FPT0WU
HT MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlPiTWM2OD12MT6wNkBvVQ>? NXHMSI12W0GQR1XS
8305C NWTLUmtWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1;KO2lEPTB;NEGuPFchdk1? M1LUWXNCVkeHUh?=
BHY MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1vhPWlEPTB;NEKuO|Ihdk1? MkHhV2FPT0WU
NTERA-S-cl-D1 M3G2e2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV\IU3lwUUN3ME20N{BvVQ>? MlntV2FPT0WU
T-24 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mlu4TWM2OD12Mz64N{BvVQ>? NXqyNYFUW0GQR1XS
EPLC-272H NVnuVVBiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWPJR|UxRTR2LkO5JI5O M{DFZXNCVkeHUh?=
PSN1 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4jqWWlEPTB;NESuOEBvVQ>? NUTlboFHW0GQR1XS
NCI-H2452 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NELhV21KSzVyPUS0MlU5KG6P NHLhWnBUSU6JRWK=
KS-1 NWLB[Go4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml\JTWM2OD12ND62OkBvVQ>? NVTrRndzW0GQR1XS
HD-MY-Z M1Lw[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnnITWM2OD12ND65NkBvVQ>? M{HpPXNCVkeHUh?=
KNS-62 NHrpPWxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFvrWIVKSzVyPUS1MlM5KG6P NHHmOFNUSU6JRWK=
NOMO-1 M2G1RWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXPJR|UxRTR3Lki3JI5O NUDzUo9IW0GQR1XS
SK-HEP-1 M1noVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmTxTWM2OD12Nj6wOEBvVQ>? M2DRfHNCVkeHUh?=
IGR-1 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M135dGlEPTB;NE[uNVMhdk1? NY\IeJZ1W0GQR1XS
KYSE-180 NEPBb|ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn\sTWM2OD12Nj6xO{BvVQ>? NYn2fopTW0GQR1XS
EW-22 NXXNdXJoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3jqWmlEPTB;NE[uNkBvVQ>? MUPTRW5ITVJ?
NCI-H1355 NUjiToVnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2LoUmlEPTB;NE[uN|Qhdk1? MXfTRW5ITVJ?
DOHH-2 MojYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVHUZZJJUUN3ME20Ok4{PyCwTR?= M1GzbnNCVkeHUh?=
A4-Fuk NXHmRWh3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVTJR|UxRTR4LkWyJI5O NGDX[VVUSU6JRWK=
PC-14 M{fzWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmDxTWM2OD12Nj61O{BvVQ>? MVTTRW5ITVJ?
TE-5 NFfZbHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{HPS2lEPTB;NE[uPFQhdk1? NHf5OJpUSU6JRWK=
LB996-RCC M{XySGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHTpPWVKSzVyPUS3MlE6KG6P Ml\YV2FPT0WU
NCI-H1623 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnnLTWM2OD12Nz63OkBvVQ>? MljGV2FPT0WU
NCI-H1155 NITVN21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIDXXJBKSzVyPUS4MlMzKG6P MUDTRW5ITVJ?
LoVo MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXrJR|UxRTR6LkSgcm0> NHrPVYxUSU6JRWK=
MCF7 NWTjc3N5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVHJR|UxRTR6LkW4JI5O NXHqfY93W0GQR1XS
AGS MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MW\JR|UxRTR6Lke3JI5O NVfqOVNxW0GQR1XS
PFSK-1 NV2zW2tHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEXoSJhKSzVyPUS5MlA3KG6P MUDTRW5ITVJ?
22RV1 MlnlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWOyc3FnUUN3ME20PU4xQSCwTR?= NIjlR|JUSU6JRWK=
COR-L23 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MY\JR|UxRTR7LkG2JI5O NUC5ZmNQW0GQR1XS
D-283MED M2rRSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mo\MTWM2OD12OT62NUBvVQ>? MnziV2FPT0WU
SW982 NWjEOIZzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIjObHNKSzVyPUS5MlkyKG6P NFzTXZBUSU6JRWK=
SW620 NVnyVVhST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXqyc25lUUN3ME21NE4{PiCwTR?= NEO2UlFUSU6JRWK=
KYSE-140 M3i3XGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mm\xTWM2OD13MD61OUBvVQ>? NIfQS3RUSU6JRWK=
GCIY NH3RfGhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3jRcmlEPTB;NUCuOlchdk1? NFrhdJhUSU6JRWK=
MHH-ESS-1 Mk\1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX\mc4NbUUN3ME21NU46PSCwTR?= NVrsTYlmW0GQR1XS
D-423MG NHHHUnZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1zjTWlEPTB;NUKuNFghdk1? MYjTRW5ITVJ?
SF539 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1Ll[mlEPTB;NUKuN|Uhdk1? NH76SJpUSU6JRWK=
RPMI-2650 MkDLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NILhV|FKSzVyPUWyMlY6KG6P MUPTRW5ITVJ?
GR-ST MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV\JR|UxRTV{Lki3JI5O NIrmU|RUSU6JRWK=
YKG-1 MmHkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWLJR|UxRTV|IH7N NYX1XFA4W0GQR1XS
SK-MES-1 NHXKSnZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3\pR2lEPTB;NUOuNlYhdk1? Mn3kV2FPT0WU
HLE M4K0NWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYjYOoJvUUN3ME21N{41PyCwTR?= M3v5T3NCVkeHUh?=
RVH-421 MnH1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn30TWM2OD13Mz62O{BvVQ>? NFvjWppUSU6JRWK=
C32 M1XlXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NITxOnVKSzVyPUWzMlg{KG6P M3HQdnNCVkeHUh?=
GB-1 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVLjXoNjUUN3ME21OE4zKG6P M1HBUXNCVkeHUh?=
SNB75 M2[2cWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn[xTWM2OD13ND6yOkBvVQ>? MXPTRW5ITVJ?
EM-2 MoHNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX\JR|UxRTV2LkSgcm0> NFnJcIlUSU6JRWK=
RH-1 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MknvTWM2OD13ND63JI5O NF7tdIRUSU6JRWK=
NKM-1 M4izZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1;ROmlEPTB;NUSuPFEhdk1? NYjSXWRNW0GQR1XS
NCI-H2405 MmfUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlvoTWM2OD13ND64PEBvVQ>? NIfCbItUSU6JRWK=
KYSE-450 NFrGN4xIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1m5bWlEPTB;NUWuNVYhdk1? M3fvT3NCVkeHUh?=
A704 MnT4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV3xbG8xUUN3ME21OU42QSCwTR?= Mn;4V2FPT0WU
HAL-01 M2PDcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmK3TWM2OD13NT64N{BvVQ>? M1;CPXNCVkeHUh?=
TE-11 NVz6Tpk3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUfBbY5TUUN3ME21OU46QSCwTR?= MY\TRW5ITVJ?
DOK MkPCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEnMS4JKSzVyPUW2MlAzKG6P MnryV2FPT0WU
KY821 M2Lmfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3fiOGlEPTB;NU[uNkBvVQ>? MUDTRW5ITVJ?
KGN M3TzSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUHJR|UxRTV4LkOyJI5O MnrRV2FPT0WU
MC116 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVroTGRyUUN3ME21O{45KG6P NHfjbVNUSU6JRWK=
PANC-08-13 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUnJR|UxRTV6LkCxJI5O M{TjWnNCVkeHUh?=
KE-37 NWH0fmtFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIPTOG5KSzVyPUW4Mlc4KG6P NFvueXZUSU6JRWK=
KYSE-410 Mn7hS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTV7LkS3JI5O NXLZV5RbW0GQR1XS
RO82-W-1 M4jDd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlXBTWM2OD13OT65JI5O NVXsVGFoW0GQR1XS
M14 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NULDPVFTUUN3ME22NE4xPCCwTR?= NV;FN2RoW0GQR1XS
GI-1 M4Wydmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVy2NIVjUUN3ME22NE4{KG6P NFryc4hUSU6JRWK=
ML-2 NVLsfVFCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUjCNnhZUUN3ME22NE43OiCwTR?= NGOyPIFUSU6JRWK=
BFTC-905 Mly4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWnlTVZoUUN3ME22NE43PSCwTR?= MXvTRW5ITVJ?
DMS-273 NHG3WlFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlOwTWM2OD14MD64O{BvVQ>? MVvTRW5ITVJ?
MDA-MB-361 NUTYcWdHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NET2V4dKSzVyPU[xJI5O NFPhRohUSU6JRWK=
MSTO-211H NXTKOlcxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoHITWM2OD14Mz61NUBvVQ>? NVG0bpJ4W0GQR1XS
MEG-01 NHi4O4NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MknZTWM2OD14Mz61NkBvVQ>? M2nNeHNCVkeHUh?=
M059J MonaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYHJR|UxRTZ|LkW4JI5O M2PMUnNCVkeHUh?=
LN-405 NVK2RmJmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmrtTWM2OD14Mz64OUBvVQ>? M2P2OXNCVkeHUh?=
NCI-H1581 NHWz[VNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NW\CcVVbUUN3ME22OE4xOyCwTR?= M{XHSnNCVkeHUh?=
TCCSUP M{K2[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MonjTWM2OD14ND61N{BvVQ>? MnjOV2FPT0WU
SW872 MmXBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoDhTWM2OD14ND61O{BvVQ>? MX;TRW5ITVJ?
KYSE-510 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3TneGlEPTB;NkWuO|Uhdk1? MkKyV2FPT0WU
NCI-H1792 NEnrSo9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3TCOmlEPTB;Nk[uNVUhdk1? NX[2bpZCW0GQR1XS
SW13 MlXQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYfVXXh4UUN3ME22Ok42KG6P Ml3CV2FPT0WU
TE-8 NVPKZmNDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWDV[4ZFUUN3ME22Ok42OiCwTR?= M2PWZnNCVkeHUh?=
SCH NWLjcpFzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEHYdXZKSzVyPU[3MlEhdk1? MmDmV2FPT0WU
NEC8 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWTJR|UxRTZ5LkK0JI5O NG\0[ZdUSU6JRWK=
HuO-3N1 M1vvbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1vaOmlEPTB;NkeuN|Ehdk1? Mn3pV2FPT0WU
EFM-19 NWrIVoI2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3vJcGlEPTB;NkeuOUBvVQ>? NGrvXlNUSU6JRWK=
HEC-1 NEPBU2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2X2e2lEPTB;NkeuOVIhdk1? NVn2VFV5W0GQR1XS
T47D NILHcnNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUnJR|UxRTZ5Lki3JI5O NUjxVYh5W0GQR1XS
SNU-423 NYPaXZN[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{\GeWlEPTB;NkeuPVghdk1? M{HaTnNCVkeHUh?=
WM-115 Ml\2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{m3NGlEPTB;NkiuNVQhdk1? NFv3VWZUSU6JRWK=
CaR-1 NF;4O3RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2raSWlEPTB;NkiuNlUhdk1? NFTUZ2pUSU6JRWK=
KU812 NHXaOZhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXHFVYdXUUN3ME22PE43QSCwTR?= MUDTRW5ITVJ?
AM-38 M3:yTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGHTbVRKSzVyPU[5MlMyKG6P NXzBOWJQW0GQR1XS
KOSC-2 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVTqc5F4UUN3ME22PU46PyCwTR?= NUHlPXRHW0GQR1XS
MC-IXC Mnv6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTdyLkC4JI5O MWDTRW5ITVJ?
SCC-4 MofxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVTJR|UxRTdzLkO4JI5O NVLiN|BtW0GQR1XS
Calu-3 Mk\WS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NELhPFlKSzVyPUexMlk5KG6P NYPTO2VoW0GQR1XS
RPMI-8866 NYfnfIlRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX;JR|UxRTd{LkiyJI5O MVHTRW5ITVJ?
OVCAR-4 NIDWTppIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGLPWHJKSzVyPUezMlM3KG6P MXfTRW5ITVJ?
OAW-42 NH3XUnhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYToR3o1UUN3ME23N{4{QSCwTR?= NIjHV5pUSU6JRWK=
ATN-1 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV3JR|UxRTd|Lki3JI5O NGfTbFFUSU6JRWK=
CHP-212 NWjoWo9vT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH25co5KSzVyPUe0Mlk2KG6P MULTRW5ITVJ?
C2BBe1 MoPSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYrtVVltUUN3ME23OU4xOyCwTR?= NYK4[IVKW0GQR1XS
A498 NXTCPJR4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXnJR|UxRTd3LkG1JI5O Mmi2V2FPT0WU
SH-4 Ml\qS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXjVW25XUUN3ME23OU4zOSCwTR?= M17Vb3NCVkeHUh?=
SNU-449 NFvYb4NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mni4TWM2OD15NT63PUBvVQ>? NGm2c|VUSU6JRWK=
RD M2Pqemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXPJR|UxRTd3Lki2JI5O NFzUZ4tUSU6JRWK=
PANC-03-27 NX7QRoE1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWHWNHBRUUN3ME23Ok4zPSCwTR?= Mn7LV2FPT0WU
S-117 M3\2Smdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MljuTWM2OD15Nj6yO{BvVQ>? NXvrT4dwW0GQR1XS
SK-MEL-2 MmfHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlG3TWM2OD15Nj63OUBvVQ>? MW\TRW5ITVJ?
LK-2 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3XpUGlEPTB;N{euNFUhdk1? M1\YeHNCVkeHUh?=
CP50-MEL-B MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmPzTWM2OD15Nz60JI5O M{D6OnNCVkeHUh?=
647-V MmHoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mk\BTWM2OD15OD6wO{BvVQ>? NIHidYdUSU6JRWK=
LU-134-A MkLGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmjwTWM2OD15OT6wN{BvVQ>? NEG5SnRUSU6JRWK=
5637 Ml7MS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXTrOY1RUUN3ME23PU4zOyCwTR?= M{PNeXNCVkeHUh?=
NCI-H1437 M4jRVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MofHTWM2OD16MD61JI5O NVrxbpQzW0GQR1XS
NCI-H460 NH76WnFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXnJR|UxRThzLkKzJI5O NVfmfpN[W0GQR1XS
BxPC-3 NWPzUHU{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX;JR|UxRThzLkS2JI5O NXf1[XY2W0GQR1XS
CAN NFm5bZhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVrJR|UxRThzLki0JI5O MVPTRW5ITVJ?
KINGS-1 Mo[2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1v6TGlEPTB;OEKuN|Ihdk1? M4fEfnNCVkeHUh?=
OCUB-M NXfnNpRST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2LvNmlEPTB;OEKuOFEhdk1? NH[4VlVUSU6JRWK=
KALS-1 MoryS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGLJVJNKSzVyPUiyMlU1KG6P MmruV2FPT0WU
OCI-AML2 M3mwNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M37WVmlEPTB;OEKuOlEhdk1? MnnYV2FPT0WU
A253 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnfMTWM2OD16Mj62OUBvVQ>? NUXKfXpjW0GQR1XS
LCLC-97TM1 NWLhO21lT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVjadJB2UUN3ME24Nk45PiCwTR?= NGXYOIdUSU6JRWK=
NCI-H520 NViweGVQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXPRfHp1UUN3ME24N{4xPiCwTR?= MojqV2FPT0WU
P30-OHK MlTXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWfNU3FmUUN3ME24N{42KG6P MWnTRW5ITVJ?
SBC-5 NXPqOndUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX;QWFhbUUN3ME24N{42OiCwTR?= Ml3UV2FPT0WU
HCE-T NHXNW2lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2HpTGlEPTB;OEOuO|Qhdk1? M3\RfHNCVkeHUh?=
JEG-3 NID5[5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFWwdHlKSzVyPUi0MlEhdk1? MUDTRW5ITVJ?
KG-1 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXzQfGNDUUN3ME24OE4zPCCwTR?= M3nSNnNCVkeHUh?=
MIA-PaCa-2 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoGwTWM2OD16ND61OEBvVQ>? M2H5[3NCVkeHUh?=
CAL-33 M2m5bmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUHvcplvUUN3ME24OU4xQCCwTR?= MVnTRW5ITVJ?
639-V NH:3NphIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX;JR|UxRTh3LkSyJI5O NFjsSnlUSU6JRWK=
NCI-H1048 NF:2eGlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVPJR|UxRTh4LkOxJI5O MkfXV2FPT0WU
NCI-H1573 NUm1UJVFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlXFTWM2OD16Nz60PEBvVQ>? Mkn1V2FPT0WU
NCI-H2228 Mom2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{fDbGlEPTB;OEiuNlYhdk1? NEjZbWJUSU6JRWK=
NB14 Ml\aS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFTmSGFKSzVyPUi4MlMhdk1? MYXTRW5ITVJ?
SCC-25 NVrvT4F4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFyyPIVKSzVyPUi5MlgzKG6P M3TMRXNCVkeHUh?=
A431 NWLqcHRlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUK4RoxsUUN3ME24PU46PyCwTR?= M4HxXXNCVkeHUh?=
SN12C NETwOWlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4\zNWlEPTB;OUCuOlIhdk1? MULTRW5ITVJ?
HuCCT1 NWrMOmpPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mmi2TWM2OD17MD63OkBvVQ>? NGfIOnJUSU6JRWK=
LS-123 NEfLWG1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MULJR|UxRTl{LkG4JI5O MmrCV2FPT0WU
CAL-85-1 M3jo[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmXUTWM2OD17Mj60PEBvVQ>? MV3TRW5ITVJ?
ES6 NGHkOpdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX\JR|UxRTl{LkizJI5O NWjkWmlLW0GQR1XS
NCI-H650 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoO5TWM2OD17ND6wPUBvVQ>? NXX2TIFZW0GQR1XS
NCI-H446 NU\oNYxYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYHJR|UxRTl3LkGyJI5O MmHiV2FPT0WU
EW-13 Mki1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV\0VnNOUUN3ME25OU44PSCwTR?= NUnEW3RMW0GQR1XS
HSC-2 M3zySmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHXWb21KSzVyPUm1Mlg6KG6P MoK1V2FPT0WU
U031 NVPSd5ZvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEjrV5pKSzVyPUm2Mlc{KG6P MoO2V2FPT0WU
EW-11 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnzSTWM2OD17Nj64PEBvVQ>? M1fVNnNCVkeHUh?=
GAK M2\wSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoGzTWM2OD17OD65N{BvVQ>? M4ru[HNCVkeHUh?=
SK-OV-3 NYPDPY9jT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV;JR|UxRTFyMD6wO{BvVQ>? NIGyN2lUSU6JRWK=
OMC-1 NYfweZNbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnLGTWM2OD1zMECuNVghdk1? M{HkZXNCVkeHUh?=
TK10 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHzT[|FKSzVyPUGwNE4zOSCwTR?= MYLTRW5ITVJ?
EKVX M33YPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnfVTWM2OD1zMECuOkBvVQ>? NHvYPIpUSU6JRWK=
Detroit562 MkT1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml3ZTWM2OD1zMEKuNVchdk1? MYnTRW5ITVJ?
SF268 MnPTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGPKTW5KSzVyPUGwNk4{PCCwTR?= MlToV2FPT0WU
SNU-387 Mn;mS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmfQTWM2OD1zMESuNVchdk1? MV3TRW5ITVJ?
MDA-MB-231 Ml\XS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NG\LOXNKSzVyPUGwOU4xPiCwTR?= M3vBZnNCVkeHUh?=
NCI-H1563 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVu2SnBmUUN3ME2xNFUvOThibl2= NH[wcZRUSU6JRWK=
D-502MG MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoPBTWM2OD1zMEWuO{BvVQ>? NUPsO3hpW0GQR1XS
A2780 NVW2VnByT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVPP[GlMUUN3ME2xNFYvPDdibl2= MkTvV2FPT0WU
IA-LM NH;WPYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYTxeZlSUUN3ME2xNFcvPTFibl2= MX;TRW5ITVJ?
D-392MG NIDRU|ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV;3T5RiUUN3ME2xNFcvPTRibl2= MXTTRW5ITVJ?
MS-1 NX;FNoxUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYSzRnFCUUN3ME2xNFcvPzFibl2= NYTSOVFLW0GQR1XS
SW1990 NWHUb5N3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH\VU5JKSzVyPUGwPE42PCCwTR?= NGXlfXBUSU6JRWK=
HEL MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2nETmlEPTB;MUC5MlI6KG6P MYjTRW5ITVJ?
SW1573 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3XhfmlEPTB;MUC5MlMyKG6P NETTe45USU6JRWK=
SW1783 NYXJWJV2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1XtZmlEPTB;MUGwMlIzKG6P MkLOV2FPT0WU
COLO-680N M3;OTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWnpeWFrUUN3ME2xNVAvPzZibl2= NYf4SXR4W0GQR1XS
NCI-N87 MmXxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVzJR|UxRTFzMT6wOEBvVQ>? M{HOV3NCVkeHUh?=
SK-MEL-28 NI\kU5RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFjsT4VKSzVyPUGxNU42PSCwTR?= NGH6R4ZUSU6JRWK=
BT-20 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYTJR|UxRTFzMj6wNUBvVQ>? MmfRV2FPT0WU
NCI-H1648 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1uzbmlEPTB;MUGzJI5O NULIVIp[W0GQR1XS
no-11 NEHqN4tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUfJR|UxRTFzMz6yPEBvVQ>? MVzTRW5ITVJ?
MOLT-13 MlLDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnS1TWM2OD1zMUOuOFQhdk1? NWG5eII2W0GQR1XS
NCI-H2170 NFzZcGZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYPrfFBoUUN3ME2xNVQvPTFibl2= Mn3ZV2FPT0WU
HTC-C3 NWGzfGZET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlPpTWM2OD1zMU[uPFUhdk1? MkC4V2FPT0WU
LU-99A MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnjLTWM2OD1zMUeuNlEhdk1? NHnWc4tUSU6JRWK=
HCC2998 Mn3pS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlXQTWM2OD1zMUeuPVIhdk1? MnOyV2FPT0WU
NB13 M2DHOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmnXTWM2OD1zMUeuPVkhdk1? M2T0WXNCVkeHUh?=
GT3TKB MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MW\JR|UxRTFzOD6wPEBvVQ>? NGL0[ZJUSU6JRWK=
BT-549 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYTQemFVUUN3ME2xNVgvQTVibl2= M{XVO3NCVkeHUh?=
NCI-H747 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFG5eW9KSzVyPUGxPU4{PCCwTR?= MWLTRW5ITVJ?
EW-1 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVjJR|UxRTF{MD6yJI5O MVTTRW5ITVJ?
LB831-BLC NEDiXYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MW\JR|UxRTF{MD62N{BvVQ>? MmDCV2FPT0WU
NMC-G1 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF23fo5KSzVyPUGyNU4yOSCwTR?= NWLPO2lWW0GQR1XS
COLO-679 NX;McWdHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnzmTWM2OD1zMkKuNVUhdk1? NHrodmZUSU6JRWK=
HL-60 M2DPWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVLORodsUUN3ME2xNlMvOSCwTR?= MX7TRW5ITVJ?
MKN7 NWrNU3VXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2\kd2lEPTB;MUKzMlg{KG6P Ml3rV2FPT0WU
RERF-LC-MS MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWD0W4hnUUN3ME2xNlQvOzFibl2= M4jpWXNCVkeHUh?=
DMS-114 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3vY[2lEPTB;MUK1MlA6KG6P M{D0bXNCVkeHUh?=
HuP-T4 NFz6fXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3HlS2lEPTB;MUK2Mlk4KG6P NVKyWFhGW0GQR1XS
HCC2157 NHHZZplIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYPJR|UxRTF{Nz61JI5O NGPvR21USU6JRWK=
SKG-IIIa NWHCTFc2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlK1TWM2OD1zMkiuPEBvVQ>? MX3TRW5ITVJ?
HCT-116 NGfu[lVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEHscHpKSzVyPUGzNE43PCCwTR?= M1nWTXNCVkeHUh?=
BB30-HNC MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV;JR|UxRTF|MD63PEBvVQ>? MliwV2FPT0WU
KYSE-270 M2XHUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWnEcIRzUUN3ME2xN|AvQDhibl2= M4\pOHNCVkeHUh?=
MFM-223 MnLCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEG4TIlKSzVyPUGzNU42OSCwTR?= NX7abpA5W0GQR1XS
NH-12 NWnwVpoxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXO3UWlIUUN3ME2xN|IvQTlibl2= NIjMclNUSU6JRWK=
U-118-MG MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUf0U4lzUUN3ME2xN|MvPjJibl2= MkHBV2FPT0WU
ESS-1 NYf3VnlQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3foXWlEPTB;MUO1MlE5KG6P MX\TRW5ITVJ?
D-247MG MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH3aWINKSzVyPUGzOU4zOSCwTR?= NHO2bnRUSU6JRWK=
IGROV-1 NVPw[o5rT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlXuTWM2OD1zM{WuO|Yhdk1? Mom5V2FPT0WU
C-33-A NWXI[mY1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2HXeWlEPTB;MUO1Mlk4KG6P NU\kcW12W0GQR1XS
NCI-H1693 M3u2Rmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWnPN5NvUUN3ME2xN|YvOTJibl2= MVfTRW5ITVJ?
MLMA MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn\zTWM2OD1zM{[uOVghdk1? MmfZV2FPT0WU
SK-N-AS NVTwdId7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIK5e|ZKSzVyPUGzO{4yPyCwTR?= MkTLV2FPT0WU
NCI-H1755 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVfJR|UxRTF|OD64OUBvVQ>? M1rhNnNCVkeHUh?=
CHP-134 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1K1cmlEPTB;MUO5MlU2KG6P NXjPbnpZW0GQR1XS
LS-513 MlWxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHvIcmxKSzVyPUG0NE46OSCyTR?= MVrTRW5ITVJ?
TE-12 NX;1SmdHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHr1epBKSzVyPUG0NE46OyCwTR?= NFPvfYdUSU6JRWK=
KNS-42 NXr0eXlFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1HNcWlEPTB;MUS0MlMhdk1? M{nFb3NCVkeHUh?=
SJRH30 MmXKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mo\ZTWM2OD1zNESuOFQhdk1? MmC2V2FPT0WU
NCI-H1092 NF;LSZBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIrZ[VBKSzVyPUG0OE42OiCwTR?= NVe0c5ZmW0GQR1XS
H-EMC-SS NGDsdJNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXrJR|UxRTF2Nj64NUBvVQ>? NFzpW|lUSU6JRWK=
SK-MEL-3 NWjhUmlKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWXLcWFlUUN3ME2xOFcvPTVibl2= NGHyXYhUSU6JRWK=
SK-N-FI M3vnR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mo\2TWM2OD1zNEeuOVkhdk1? MoLiV2FPT0WU
NCI-H2126 MnXvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{[1S2lEPTB;MUS4MlE2KG6P NF;oWIxUSU6JRWK=
NCI-H1299 NXvGbZpXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NU\vXmM2UUN3ME2xOVAvOjJibl2= MXLTRW5ITVJ?
CFPAC-1 NIW4dFFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M37wbWlEPTB;MUWwMlY3KG6P NFP3XIlUSU6JRWK=
NCI-H661 NYfQOocxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF7uR4JKSzVyPUG1NU4zPiCwTR?= MlXUV2FPT0WU
KYSE-70 NWLNNXJGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF3lVmhKSzVyPUG1NU44QSCwTR?= M{\mRXNCVkeHUh?=
SW900 NHXZWJZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3vCOmlEPTB;MUW0MlY2KG6P NFfSW|lUSU6JRWK=
Ca-Ski Mme0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXvJR|UxRTF3Nj6zPUBvVQ>? Mk\qV2FPT0WU
HPAF-II NF3ZdohIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUPJR|UxRTF3Nj60O{BvVQ>? M133cnNCVkeHUh?=
LB2518-MEL NUPKOIJOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3viWGlEPTB;MUW3MlEhdk1? M{HvVXNCVkeHUh?=
LC-2-ad M{nwdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{XDdGlEPTB;MUW4MlYzKG6P NF7XVHFUSU6JRWK=
HCC1806 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2TSO2lEPTB;MU[3Mlg5KG6P MnP3V2FPT0WU
UACC-62 MmLrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTF4OD6wPUBvVQ>? MkK5V2FPT0WU
KM-H2 NG\BXnJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlqyTWM2OD1zN{CuOVghdk1? M{fGXXNCVkeHUh?=
NCI-H2347 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXrJR|UxRTF5Mj63NkBvVQ>? MUXTRW5ITVJ?
SCC-15 M4G4PGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX;xVIhuUUN3ME2xO|MvPjZibl2= MX\TRW5ITVJ?
BB49-HNC NGTXUGNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVPJR|UxRTF5Mz64NUBvVQ>? MUDTRW5ITVJ?
GMS-10 M17Dc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWrTO2NYUUN3ME2xO|MvQTRibl2= NEG2Vm9USU6JRWK=
NCI-H2052 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVTWU3RVUUN3ME2xO|QvQSCwTR?= Mk\ZV2FPT0WU
SW626 M2LG[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnXOTWM2OD1zN{[uNFYhdk1? NW[3OI5KW0GQR1XS
MDA-MB-415 NWLy[|hlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmnPTWM2OD1zN{[uOlEhdk1? M2W5U3NCVkeHUh?=
Saos-2 MlTxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGTncm1KSzVyPUG3PU4{PSCwTR?= Ml\YV2FPT0WU
DK-MG MojVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUfROJdHUUN3ME2xPFAvOyCwTR?= NX\VWWt{W0GQR1XS
SNU-C2B NXrXO3RYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3\ndmlEPTB;MUiwMlc{KG6P M3O0R3NCVkeHUh?=
A427 MnP4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVHRdmxkUUN3ME2xPFIvPTdibl2= M3jXOHNCVkeHUh?=
KP-N-YS MkTrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYnJR|UxRTF6NTDuUS=> NE\HVZhUSU6JRWK=
J82 MnTiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYfJR|UxRTF6NT6xPEBvVQ>? M37rVnNCVkeHUh?=
LS-411N MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVfJR|UxRTF6Nz6yPEBvVQ>? MULTRW5ITVJ?
HCC1937 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHnvboFKSzVyPUG4O{41QSCwTR?= NEPsNFBUSU6JRWK=
OE33 M1jsPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX;EVFN{UUN3ME2xPFgvQTdibl2= MoD4V2FPT0WU
NB7 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGDRe21KSzVyPUG4PU45QSCwTR?= NGP1N3dUSU6JRWK=
SW684 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFnNeWhKSzVyPUG5Ok4yOyCwTR?= NEPhW49USU6JRWK=
HT-144 NV;DcpRtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlvnTWM2OD1zOU[uNVUhdk1? M2DH[nNCVkeHUh?=
SK-MEL-30 NGHPb5VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXPIcmVMUUN3ME2xPVYvOiCwTR?= Mm\TV2FPT0WU
DBTRG-05MG MkXpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV3JR|UxRTF7OD60O{BvVQ>? NFvkcJFUSU6JRWK=
NCI-H1395 M1\2c2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1q0[WlEPTB;MUm4Mlg2KG6P NVPhe|lxW0GQR1XS
NCI-H2122 MkPyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXTofWZVUUN3ME2yNFAvPTlibl2= NGmyNHZUSU6JRWK=
no-10 NHfFTYJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVvJR|UxRTJyMT6wOEBvVQ>? MYLTRW5ITVJ?
SW48 NXHnXG1ET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXW3dWREUUN3ME2yNFEvOzFibl2= NF7sSIJUSU6JRWK=
NCI-H1650 Mn\MS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2XTUGlEPTB;MkC0MlAyKG6P M3np[3NCVkeHUh?=
MZ1-PC MmT3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV;OSXdwUUN3ME2yNFUvPThibl2= NIrh[2dUSU6JRWK=
U-266 NHzQfGlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIjzfoRKSzVyPUKwOU44QSCwTR?= NYX1ZoM{W0GQR1XS
CAS-1 NYi3UVZOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2\afWlEPTB;MkC3MlQ1KG6P NYrKWnN3W0GQR1XS
AU565 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVv1OlliUUN3ME2yNVIvQDJibl2= MkTPV2FPT0WU
UACC-257 MkXES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHvZV2ZKSzVyPUKxN{46QSCwTR?= NVLK[2VYW0GQR1XS
CAL-27 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml;nTWM2OD1{MUeuNFUhdk1? M3LiZXNCVkeHUh?=
NCI-H23 NXn6NFhDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVTJR|UxRTJzOT6zN{BvVQ>? NHrnTpZUSU6JRWK=
TE-6 M2[wZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmDSTWM2OD1{MUmuOlghdk1? NUDreFNOW0GQR1XS
TGBC24TKB MoXWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3njNWlEPTB;MkKyMlE4KG6P NYrne3ZSW0GQR1XS
TE-1 MlrLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWO3cGlMUUN3ME2yNlIvQDhibl2= MXHTRW5ITVJ?
RCC10RGB M1nneGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHvDWJpKSzVyPUKyOE4yQSCwTR?= NFzjT45USU6JRWK=
NCI-H596 M2\USWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUXJR|UxRTJ{OD6yNkBvVQ>? NV\SV|E{W0GQR1XS
SW954 NEX2PIJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUDJR|UxRTJ|Mz64N{BvVQ>? M2e1fHNCVkeHUh?=
NCI-H2087 NWfkcIx5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUnJR|UxRTJ|ND61NUBvVQ>? MVvTRW5ITVJ?
SK-PN-DW NIjSXJhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX\JR|UxRTJ|NT6xPUBvVQ>? M3jYc3NCVkeHUh?=
KM12 MkD2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWTPW4xFUUN3ME2yN|UvPyCwTR?= NImwOlVUSU6JRWK=
BT-474 NHzYdpJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV\JR|UxRTJ|NT63N{BvVQ>? MVHTRW5ITVJ?
IST-MES1 M{PWdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVLwN|VlUUN3ME2yN|YvPTdibl2= MorkV2FPT0WU
HT-1197 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV;5PGF{UUN3ME2yN|gvODlibl2= MlziV2FPT0WU
CAL-54 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEDVNphKSzVyPUKzPE41QSCwTR?= MUnTRW5ITVJ?
NB10 MlrYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTJ2MD6wOkBvVQ>? MXvTRW5ITVJ?
PANC-10-05 NVPBWos3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWrJR|UxRTJ2NT61OkBvVQ>? MlWwV2FPT0WU
NCI-H522 MoTyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{\YNGlEPTB;MkS4MlMyKG6P NU\rdmJQW0GQR1XS
A388 NIfsOXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn;iTWM2OD1{NEmuPFIhdk1? NW[2WoxtW0GQR1XS
GOTO NFnqNJhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGnRNo1KSzVyPUK1NE4zQSCwTR?= M33F[HNCVkeHUh?=
KLE NV7se4VwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4[5OGlEPTB;MkWxMlg4KG6P NHLwRYhUSU6JRWK=
KYSE-520 NHXrUFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHfRZm5KSzVyPUK1Nk45PiCwTR?= MVnTRW5ITVJ?
HCE-4 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml;UTWM2OD1{NkKuOUBvVQ>? M{LjNHNCVkeHUh?=
KURAMOCHI NXzWfIdvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGPHUGRKSzVyPUK2OU46KG6P MnLnV2FPT0WU
HCC38 MnrQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX3YXHljUUN3ME2yOlYvPDhibl2= M1THXXNCVkeHUh?=
FADU NYmxZ5dMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3zCSGlEPTB;Mk[2MlY{KG6P NELCPVhUSU6JRWK=
CW-2 NVSzV4ZJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFXsPXlKSzVyPUK2PU46PiCwTR?= MkXGV2FPT0WU
L-428 M3PBdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVXJR|UxRTJ5NT6xOUBvVQ>? NEPsWlZUSU6JRWK=
HCC1569 NEPab|FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGjG[2FKSzVyPUK3OU45PCCwTR?= NUS5VnpzW0GQR1XS
NCI-H810 M{PDfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIXnSXRKSzVyPUK3PE4{OSCwTR?= NEDUUnFUSU6JRWK=
LB771-HNC NEPy[ZNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoHxTWM2OD1{OEWuPFQhdk1? NGm2UotUSU6JRWK=
LCLC-103H NVvRboNRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml;1TWM2OD1{OEWuPVkhdk1? MlTXV2FPT0WU
EFO-21 M2nzeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MW\JR|UxRTJ6Nz62PEBvVQ>? M1fidXNCVkeHUh?=
CAL-72 NH:1W4FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF7KcWZKSzVyPUK5N{4yQSCwTR?= NXjYd2FrW0GQR1XS
SCC-9 M2HCeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWXE[XNbUUN3ME2yPVMvOjJibl2= MYjTRW5ITVJ?
COLO-829 NXzzfGpoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MULJR|UxRTJ7Nj61JI5O MkjhV2FPT0WU
U-87-MG MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGXSVW5KSzVyPUOwNE44OyCwTR?= MmTaV2FPT0WU
MZ7-mel M4PQXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{jQcGlEPTB;M{KzMlc3KG6P NYj4V214W0GQR1XS
NCI-H1770 MkDBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3fyWGlEPTB;M{K2Mlc1KG6P MYjTRW5ITVJ?
ChaGo-K-1 MmPzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3LsfWlEPTB;M{K4MlEhdk1? MnW4V2FPT0WU
SiHa NHnFZXBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnvvTWM2OD1|MkmuNlQhdk1? MXHTRW5ITVJ?
NCI-SNU-5 M4j3emdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3P1SmlEPTB;M{O2Mlc4KG6P NHWwSo9USU6JRWK=
DJM-1 Mn7GS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1GycGlEPTB;M{SwMlM{KG6P M4i0bHNCVkeHUh?=
OE19 M4LtTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWfJR|UxRTN2MD61N{BvVQ>? Ml\XV2FPT0WU
NCI-H1651 NIjxToFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnyzTWM2OD1|NESuNVghdk1? NID5N5RUSU6JRWK=
COLO-792 M3[3bmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3fxV2lEPTB;M{W0MlQzKG6P M1LvenNCVkeHUh?=
ACHN M3XrOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGfEN2hKSzVyPUO1Ok44OSCwTR?= Ml\zV2FPT0WU
TH-3 MkL2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF7iNFNKSzVyPUO3PU46PSCwTR?= M2niRnNCVkeHUh?=
HT-1376 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYHJR|UxRTN6ND64PEBvVQ>? NYLR[nJPW0GQR1XS
RH-18 NF3qTHlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHXL[VVKSzVyPUO5OE44PCCwTR?= NYPDTWd1W0GQR1XS
NB6 MlPZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWjN[oVMUUN3ME2zPVYvPjZibl2= NEPqb5VUSU6JRWK=
COLO-320-HSR NYHaTHBRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUHJR|UxRTRyMz6zO{BvVQ>? MlXBV2FPT0WU
UACC-893 M2jJRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFfScHhKSzVyPUSwOk41PyCwTR?= NEDlR5dUSU6JRWK=
DSH1 NVLD[Il5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGrLOo5KSzVyPUSwOk46OSCwTR?= MoPDV2FPT0WU
TE-10 M3O0ZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{j3NWlEPTB;NEC3MlAyKG6P MmHoV2FPT0WU
HCC70 NVX2SHY3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NE\uVVFKSzVyPUSwPU4zOSCwTR?= M2mzeXNCVkeHUh?=
TGBC11TKB NX;i[o43T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXvjdW0yUUN3ME20NVAvOzNibl2= NFL2S2tUSU6JRWK=
NCI-H727 M3TIPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHLmdHNKSzVyPUSxNk4yOSCwTR?= M171W3NCVkeHUh?=
ALL-PO NFyzW2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1LRSGlEPTB;NEG1MlY6KG6P Ml;mV2FPT0WU
ABC-1 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFywd5RKSzVyPUSyNE41PSCwTR?= M3TMTnNCVkeHUh?=
NCI-H69 NVrjOlNOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXjCdnFTUUN3ME20NlYvPzZibl2= MYjTRW5ITVJ?
GP5d MoHLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIHjTJVKSzVyPUSzOE41OSCwTR?= MoPEV2FPT0WU
UMC-11 MkXCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF3RWGNKSzVyPUS1PE4{PiCwTR?= MlvBV2FPT0WU
RMG-I MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIe4WmhKSzVyPUS2O{42PiCwTR?= M3flUXNCVkeHUh?=
YAPC NFGyUpZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWrJR|UxRTR7MD62JI5O NUDmbVBGW0GQR1XS
LS-1034 M{HuSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4LHd2lEPTB;NEmxMlA3KG6P NXywbFN6W0GQR1XS
RCM-1 NUjXRXRsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUDrPVBvUUN3ME20PVYvPjhibl2= MXPTRW5ITVJ?
HCC1954 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkfpTWM2OD13MUKuOUBvVQ>? NIjVNmZUSU6JRWK=
SK-MEL-24 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVvR[YlIUUN3ME21NVYvPTFibl2= M1HXZnNCVkeHUh?=
NB12 NEDvZmpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkTQTWM2OD13MkiuOFIhdk1? NULtephtW0GQR1XS
SW756 M2T4[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX7JR|UxRTV3ND65OkBvVQ>? Ml3BV2FPT0WU
HCC1187 NFfsWnVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2\FTWlEPTB;NUe1Mlg{KG6P MV;TRW5ITVJ?
NCI-H2342 NWn4OIF[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{LCSmlEPTB;NUmwMlM6KG6P M3rMSXNCVkeHUh?=
NCI-H2291 MoGxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmrSTWM2OD13OUiuN|Ehdk1? NIHjdYJUSU6JRWK=
OVCAR-3 NEfjO5RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NW\MV2t6UUN3ME21PVgvQTZibl2= NFzaVoxUSU6JRWK=
MHH-NB-11 NWDkV4h[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFf0ToZKSzVyPU[yPU4xOSCwTR?= NIPhUFNUSU6JRWK=
SAS MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NW\xeoVUUUN3ME22OVIvPjdibl2= NGjVUoNUSU6JRWK=
COLO-824 NWrNPW9XT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnTmTWM2OD14OEmuN|chdk1? NHXqOpFUSU6JRWK=
HCC1395 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn7zTWM2OD14OUiuOUBvVQ>? M3:2VXNCVkeHUh?=
COLO-668 M1\lfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVfIdXREUUN3ME23NFYvOSCwTR?= M121WHNCVkeHUh?=
NCI-H226 NVnKU243T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWPRNHdQUUN3ME23NFcvQCCwTR?= MWfTRW5ITVJ?
NB17 MlqxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoG5TWM2OD15MkGuO|Uhdk1? NVyxRYVTW0GQR1XS
SW1463 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUjJR|UxRTd|OT6xPUBvVQ>? NGTadoxUSU6JRWK=
TGW NGrpe4dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXrJR|UxRTd4MD6xOUBvVQ>? NGDKTohUSU6JRWK=
NCI-H526 NVnMWZcyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXLufIZWUUN3ME24NlMvPTNibl2= M1qyR3NCVkeHUh?=
COR-L88 M3j3VGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV7JR|UxRTh2OD6xNkBvVQ>? M360UnNCVkeHUh?=
NCI-H441 NVTG[4RKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGr4U3FKSzVyPUi5OU4zOiCwTR?= NWjIXGNsW0GQR1XS
NCI-H630 NVTVOIFjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUnJR|UxRTlzMj65OkBvVQ>? M4LEXnNCVkeHUh?=
Mo-T Mmf6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX;xOmR5UUN3ME25OFcvQDhibl2= MmPpV2FPT0WU
JAR MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn;CTWM2OD17NU[uNlQhdk1? NVW5PG96W0GQR1XS
NCI-H1838 NX7pdWJ7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX61VmNrUUN3ME2xMlAzOzh6IN88US=> M1W3SHNCVkeHUh?=
DoTc2-4510 MmfwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NInqUHNKSzVyPUGuNFc{PzZizszN NH3DOm5USU6JRWK=
MKN28 NXnrbpFET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnGwTWM2OD1zLkC5NFI1KM7:TR?= MVHTRW5ITVJ?
HuP-T3 MoTIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml\NTWM2OD1zLkGxPVA2KM7:TR?= MkfGV2FPT0WU
TE-9 MkXIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTFwMUK5O|Mh|ryP NFi1OlVUSU6JRWK=
NY MmLFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn33TWM2OD1zLkG2O|kzKM7:TR?= M4m2cnNCVkeHUh?=
HT55 NGjFXmFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVWwZmtpUUN3ME2xMlMyOzR2IN88US=> M{faXHNCVkeHUh?=
SW837 NWrGcoZ4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2Ha[mlEPTB;MT6zNlk4QCEQvF2= Ml3ZV2FPT0WU
NCI-H2029 M4fnNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEW3d|lKSzVyPUGuOFE4QTFizszN MoXxV2FPT0WU
IST-SL1 NFrnUG9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYLwSI46UUN3ME2xMlQ1OjRizszN NVjafJF1W0GQR1XS
COLO-741 MmjvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX2yc|JvUUN3ME2xMlQ6PzdzIN88US=> M3\0SnNCVkeHUh?=
LU-65 M3P1[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mle4TWM2OD1zLk[yNlQ6KM7:TR?= NEDrdnBUSU6JRWK=
NCI-H1304 NGrKOFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmHlTWM2OD1zLk[1OFk5KM7:TR?= NV25eGxZW0GQR1XS
KARPAS-299 NILEfYFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NY\FZolmUUN3ME2xMlc6PDd7IN88US=> M3fOb3NCVkeHUh?=
NCI-H358 M4jaXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnHETWM2OD1zLkm1OVA{KM7:TR?= MlnKV2FPT0WU
OAW-28 MnL0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHrBSlhKSzVyPUKuNFY6OTlizszN NULXXHZ2W0GQR1XS
C8166 MoPOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnnxTWM2OD1{Lk[zN|kzKM7:TR?= NVnHbJdKW0GQR1XS
COLO-678 M3jKVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFy0e4tKSzVyPUKuPFM4PjhizszN MmTpV2FPT0WU
SK-N-DZ NVLlZZEzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M33GTGlEPTB;Mj64OlM5OSEQvF2= NVHhWI5FW0GQR1XS
NCI-H82 MofDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYXJR|UxRTJwOUCzOlkh|ryP NX7DZVBvW0GQR1XS
JVM-2 NYGzU3lST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{DHXmlEPTB;Mz6wN|E5QCEQvF2= M{\UXHNCVkeHUh?=
SW1116 NUTyTmNTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXHJR|UxRTNwMEW0NVEh|ryP NH\mNlFUSU6JRWK=
MDA-MB-453 NELkT5hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYLSUoFtUUN3ME2zMlExPDN7IN88US=> MYHTRW5ITVJ?
Calu-6 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXzJR|UxRTNwMUm5O{DPxE1? NXnUTVBUW0GQR1XS
SHP-77 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkPGTWM2OD1|LkWyPEDPxE1? MXXTRW5ITVJ?
Capan-2 M3\0UGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVH6S5ZzUUN3ME20MlMzPThzIN88US=> NHKw[FFUSU6JRWK=
SW948 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGHObVhKSzVyPUSuO|Q4PzlizszN M1SwNXNCVkeHUh?=
HDLM-2 NGXzblhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml3FTWM2OD13LkC3O|I2KM7:TR?= MXXTRW5ITVJ?
LAN-6 M1:ySGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFjPXI1KSzVyPU[uNlE1QTVizszN MUXTRW5ITVJ?
LU-135 NHzaRXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmfSTWM2OD14LkSzNFc4KM7:TR?= NUD0d2NTW0GQR1XS
T84 NWHrdlBqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoTrTWM2OD14Lkm4OlQh|ryP MYXTRW5ITVJ?
CAPAN-1 NWfMOWkxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHrKS5lKSzVyPUeuOlIzOzNizszN MY\TRW5ITVJ?
SW1417 NHmybHFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV7JR|UxRTdwOUG3N|Eh|ryP MmHQV2FPT0WU
BALL-1 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2fwS2lEPTB;OD61NFQxQSEQvF2= MlXmV2FPT0WU
HT-29 Mor3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1S0b2lEPTB;OT6wO|U6QSEQvF2= MXLTRW5ITVJ?
C3A NWSxN4szT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUPtdZFpUUN3ME25Mlg5Ozl2IN88US=> M1S5OXNCVkeHUh?=
NCI-H1993 NHvHPVZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmfITWM2OD1zMD61NFgyKM7:TR?= M3L5NXNCVkeHUh?=
SK-MEL-1 NVPjWGM2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVjBenM5UUN3ME2xNU43Ojh7IN88US=> NEHHTYtUSU6JRWK=
DU-145 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWTWXIxYUUN3ME2xOE42ODV{IN88US=> M{m0eXNCVkeHUh?=
KP-N-YN MoPkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mmr2TWM2OD1zND61NVA{KM7:TR?= M{j2XXNCVkeHUh?=
CCRF-CEM MlLaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVTJR|UxRTF2Lke4NFkh|ryP MYrTRW5ITVJ?
ZR-75-30 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYXRT2lLUUN3ME2xOk4{OzB|IN88US=> M{jvOXNCVkeHUh?=
A673 NILjenFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEK1cHJKSzVyPUKwMlU2ODdizszN MmG3V2FPT0WU
K-562 NYnLcWVLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIHlcWdKSzVyPUK4MlQyQDNizszN M2n1cnNCVkeHUh?=

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
Myc / Vinculin / pT58 Myc; 

PubMed: 25934076     


Immunoblots documenting MYC and pT58 MYC stability. SW480 cells were treated with 200nM BEZ235 or solvent control for 24h and cycloheximide (50µg/ml) and harvested at the indicated time points. Vinculin was used as loading control. Exposures of MYC and pT58 MYC blots were adjusted to equalize exposure at 0 min (n=3; unless otherwise indicated, n indicates the number of independent biological repeat experiments in the following legends).

pAkt / Akt / Skp2 / AR / pS6 / p27; 

PubMed: 24347472     


BEZ235 decreases Skp2 and increases AR protein expression inC4-2B cells. Cells were treated with BEZ235 at various doses. Cell lysates were subjected to Westernblot analysis with indicated antibodies. 

p-S6K / S6K / p-Akt / Akt / p-ABL / BCR-ABL; 

PubMed: 28435223     


Dose-dependent inhibition effect of BEZ235 on the phosphorylation levels of S6K, Akt (Ser473), and BCR–ABL in CML cells. Results of Western blot.

Bcl-2 / Caspase-3 / Cleaved caspase-3 ; 

PubMed: 28435223     


K562 (A1) and KBM7R (A2) cells were treated with BEZ235 for 24 h; total protein lysates were immunoblotted with antibodies for Bcl-2, caspase-3, and cleaved caspase-3. 

Cyclin D1 / Cyclin D2 ; 

PubMed: 28435223     


Dose-dependent inhibition effect of BEZ235 on the expression levels of cyclin D1 and cyclin D2 in K562 and KBM7R cells. Western blot results of K562 (A1) and KBM7R (A2) cells.

mTOR / p-mTOR / p70S6K / p-p70S6K ; 

PubMed: 29581778     


Eca-109 cells was treated with increasing concentration of BEZ235 (0, 100, 200 and 500 nM) for 48 hours. Western blot showed the inhibition effect of PI3K/mTOR pathway was dose dependent. 

p-EGFR-Tyr1068 / EGFR / p-HER2-Tyr1221 / p-HER2-Tyr1222 / HER2 / p-HER3-Tyr1289; 

PubMed: 21278786     


Immunoblots of protein lysates from BT474 and MCF7-HER2 cells treated with either BEZ235 alone (0–500 n) or the combination of BEZ235 (0–500 n) and the tyrosine kinase inhibitor lapatinib (LAP, 500 n) for 24 h. 

25934076 24347472 28435223 29581778 21278786
Immunofluorescence
SP1; 

PubMed: 26336820     


Immunofluorescence assessment of SP1 after BEZ235 treatment for 24 hrs in A673, SKNMC cells and in HFF.

p-ErbB2(Y1248); 

PubMed: 24675532     


Immunofluorescence staining of BT474.LapR cells grown in 3-D culture under different treatment conditions for a week. Scale bar indicates 50 μm.

LC3; 

PubMed: 23603977     


(A) SU-2 cells were treated with NVP-BEZ235 (10 nmol/L) for 12 h and then harvested 24 h after treatment with IR (8 Gy), and analyzed for LC3 expression (top) or the formation of autophagolysosomes by using MDC (middle) and LTR (bottom) by immunofluorescence analysis (600×magnification).

26336820 24675532 23603977
Growth inhibition assay
Cell viability (P3, U87); 

PubMed: 27542970     


IC50 doses of dactolisib for P3 (left) and U87 (right) glioma cells, generated from MTS assay. 

Cell viability (breast cancer cells); 

PubMed: 28060760     


Cell viability of breast cancer cells treated by either BEZ235 or TSA for 48h was measured by MTT assay. Each cell line was analyzed in triplicate, and a representative experiment is shown. 

Cell viability (K562, KBM7R); 

PubMed: 28435223     


(A) K562 cells were treated with increasing concentrations of BEZ235 for 24, 48, or 72 h and subjected to MTS assay. (B) KBM7R cells were treated with increasing concentrations of BEZ235 for 24, 48, or 72 h and subjected to MTS assay. (C) K562 cells were treated with imatinib (0–10 μM) alone or imatinib and BEZ235 (0.2 μM) for 48 h and subjected to MTS assay. (D) KBM7R cells were treated with imatinib (0–10 μM) alone or imatinib and BEZ235 (0.2 μM) for 48 h and subjected to MTS assay. Mean ± SD. n=3. *P<0.05, compared to the control group. #P<0.05, compared to the group of IM alone.

27542970 28060760 28435223
ELISA
VEGF; 

PubMed: 19671762     


NVP-BEZ235 attenuated VEGF secretion by at least 40% in U87 cells. The VEGF level in the serum-free medium was measured in triplicate and the experiment repeated at least twice to confirm results.

19671762
体内研究 BEZ235诱导肿瘤(69%)消退,而对体重增加没有统计学上显著的作用。总之,这些初步的体内功效研究结果表明,BEZ235单一口服给药时能够阻断疾病的发展,与其他抗癌药结合使用时能够增强疗效。[1]

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

激酶实验:

[2]

- 合并

体外蛋白激酶,PI3K,和mTOR实验:

PI3Kα, β, δ蛋白都由与p110全长蛋白相接的p85 N端的iSH2域组成,只是PI3Kα没有最后的20个氨基酸。PI3Kγ由p110全长蛋白去掉前144个氨基酸产生而来。所有PI3K蛋白在羧基末端加组氨酸标签便于纯化,然后克隆到pBlue-Bac4.5 (用于α, β,和δ亚型) 或者pVL1393 (用于γ 亚型) 质粒中。转染BaculoGold WT基因组DNA的不同的载体按说明书推荐的方法生产各自重组体杆状病毒及重组蛋白。使用激酶发光检测试剂盒测定BEZ235 (NVP-BEZ235)作用于PI3K的活力。在384孔板上进行激酶实验。在每个孔中加入50 nl的测试项目(溶在90%DMSO中)和5ul的反应buffer,反应buffer包含10 μg/ml PI基质 (l-α-磷脂酰肌醇; 由Avanti Polar Lipids提供;预备在3%辛基葡萄糖苷中),然后加入PI3K 蛋白(p110α, p110β, p110δ,和p110γ分别为10, 25, 10,和150 nM)。加入预备在反应buffer中的5 ul 1 µM 的ATP反应开始,反应进行60分钟 (测p110α, p110β, p110δ)或者120分钟(测p110γ),随后加入10ul的荧光激酶buffer终止反应。数据用Synergy 2 阅读器阅读用于荧光测试。
细胞实验:

[1]

- 合并
  • Cell lines: HCT116, DLD-1, SW480
  • Concentrations: 0-1 μM
  • Incubation Time: 48小时
  • Method:

    HCT116 (PIK3CA突变型; 激酶域在H1047R), DLD-1 (PIK3CA突变型;螺旋域在E545K), SW480 (PIK3CA 野生型)人类CRC细胞系,同基因型的DLD-1 PIK3CA突变和野生型细胞培养在含10%FBS和1×青霉素/链霉素的培养基中。细胞按不同的初始密度加入(HCT116: 3000个细胞/每孔, DLD-1: 5500个细胞/每孔, SW480: 4500个细胞/每孔, DLD-1 PIK3CA突变型: 7000个细胞/每孔, DLD-1 PIK3CA野生型: 9000个细胞/每孔),用来计算不同的生长动力学。16个小时后,细胞加入浓度越来越高的BEZ235中进行温育,含有药物的培养基24小时更换一次。根据产品说明书,加入细胞16小时和药物处理48小时,使用单溶液细胞增殖检测试剂盒以比色法检测细胞活力。与没有用药物处理正在生长的细胞相比,药物处理的细胞的活力也逐渐趋于正常化。使用GraphPad Prism 5软件用4个参数的回归曲线计算IC50值。用于western blot 分析,细胞用0 nM 或者最高抑制剂量(500 nM) BEZ235处理 2, 6, 24, 或者48 小时。


    (Only for Reference)
动物实验:

[2]

- 合并
  • Animal Models: 雌性Harlan无胸腺裸鼠
  • Dosages: 45 mg/kg
  • Administration: 口服处理
    (Only for Reference)

溶解度 (25°C)

体外 DMF 18 mg/mL warmed (38.33 mM)
DMSO 0.01 mg/mL (0.02 mM)
Water Insoluble
体内 从左到右依次将纯溶剂加入产品,现配现用(数据来自Selleck实验检测而非文献):
NMP+PEG300 (10+90, v+v)
30 mg/mL

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 469.55
化学式

C30H23N5O

CAS号 915019-65-7
储存条件 粉状
溶于溶剂
别名 NVP-BEZ235

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系Selleck为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % ddH2O
计算重置

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: