所有产品

目录号	产品名	产品描述
E7397	(+)-Falcarindiol	Falcarindiol is a cytotoxic and anti-inflammatory polyacetylenic oxylipin found in food plants of the Apiaceae family, such as carrots. It functions as a partial agonist of peroxisome proliferator-activated receptor γ (PPARγ) with an EC50 of 3.29 µM in a luciferase reporter assay, leading to the upregulation of the cholesterol transporter ABCA1 in cells. It also promotes a beige adipocyte-like phenotype and enhances mitochondrial respiration in human preadipocyte-derived adipocytes.
S3611	(+)-Fangchinoline	Fangchinoline ((+)-Limacine, Tetrandrine B, Hanfangichin B) is a phytochemical that has been shown to elicit anti-cancer effects in prostate and breast cancer cell lines via inducing G1 cell cycle arrest. It has also been shown to possess neuroprotective activity.
S5934	(-)-Fenchone	Fenchone is a constituent of absinthe and the essential oil of fennel. It is used as a flavor in foods and in perfumery.
S6107	1-Furfurylpyrrole	1-Furfurylpyrrole (N-Furfurylpyrrole) is a potential contributor of flavor and aroma to popcorn.
S7153	10058-F4	10058-F4 is a c-Myc inhibitor that specificallly inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression. 10058-F4 promotes a caspase-3-dependent apoptosis and modulates autophagy.
S6320	2,5-Furandicarboxylic acid	2,5-Furandicarboxylic acid (Dehydromucic acid) is a normal urinary metabolite in humans and an important renewable building block because of its potential as a substitute for a variety of petrochemicals, such as terephthalic acid and adipic acid.
S4864	2-Furoic acid	2-Furoic acid (2-Furancarboxylic acid, Pyromucic acid, 2-Carboxyfuran, α-furancarboxylic acid, α-furoic acid) is an organic compound most widely found in food products as a preservative and a flavoring agent.
E8048	2-Furoyl-LIGRLO-amide	2-Furoyl-LIGRLO-amide is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD2 value of 7.0..
E7837	2F-Peracetyl-Fucose	2F-Peracetyl-Fucose (1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos) acts as a potent fucosyltransferase (FUT) inhibitor.
S6848	3'-Fluoro-3'-deoxythymidine (Alovudine)	3'-Fluoro-3'-deoxythymidine (Alovudine, CL 184824, FddThd, FLT, MIV-310) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the chemotherapy of pancreatic cancer.
S6097	3-Furoic acid	3-Furoic acid is an organic acid regularly occurring in urine of healthy individuals.
E6600	3FAx-Neu5Ac	3FAx-Neu5Ac is a fluorinated sialic acid analogue and an inhibitor of Sialyltransferase. It inhibited sialylation, leading to reduced MHC expression and suppression of myoblast fusion, suggesting that modulation of sialylation can be applied to regulate skeletal muscle cell differentiation.
E0070	4F 4PP oxalate	4F 4PP oxalate is an antagonist of the serotonin (5-HT) receptor subtype 5-HT2A (Ki = 5.3 nM), which is selective for 5-HT2A receptors over 5-HT1C receptors (Ki = 620 nM).
F5028	4F2hc/CD98 Antibody [J3D15]
S0550	5'-Fluoroindirubinoxime	5'-Fluoroindirubinoxime (5’-FIO, compound 13), an indirubin derivative, is a potent FLT3 inhibitor, with an IC50 of 15 nM.
E7233	5(6)-FITC	5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm.
E7202	5-FAM	5-FAM (5-Carboxyfluorescein) is a green fluorescent reagent used for in situ labeling peptides, proteins and nucleotides. 5-FAM is a single isomer with Ex/Em of 490 nm/520 nm.
S9873	5-Fluoroorotic acid	5-Fluoroorotic acid (5-FOA, 5-Fluoroorotate, NSC 31712) is a selective agent in yeast molecular genetics. 5-Fluoroorotic acid possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects.
S1209	5-Fluorouracil (5-FU)	5-FU (5-Fluorouracil) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV.
E5785	5-Fluorouridine	5-Fluorouridine is a uridine analog and a potent inhibitor of ribozyme self-cleavage with an EC50 of 5.9 μM. It significantly inhibit ribozyme function via its covalent incorporation into the mRNA carrying the ribozyme sequences and can be used as used chemotherapeutic agent in cancer research.
E7172	6-FAM	6-FAM (6-Carboxyfluorescein) is an isomer of carboxyfluorescein and is mainly used for sequencing and labeling of nucleic acids.
E7943	6-FITC	6-FITC (6-Fluorescein Isothiocyanate) is a derivative of fluorescein used in wide-ranging applications including flow cytometry.
S0302	F1063-0967	F1063-0967 is an inhibitor of Dual-specificity phosphatase 26 (DUSP26) with IC50 of 11.62 μM.
F2107	FAAH1 Antibody [J10G16]
S2474	Fabomotizole hydrochloride	Fabomotizole hydrochloride (Fabomotizole, CM346, CM346, Afobazol, Afobazole) exhibits anxiolytic and neuroprotective properties. Fabomotizole hydrochloride is a potent sigma1-receptor agonist with IC50 of 7.1 µM and Ki of 5.9 µM.
A5812	FABP3 Rabbit Recombinant mAb	FABP3 Rabbit Recombinant mAb detects endogenous levels of total FABP3.
F1600	FABP4 Antibody [M24L23]	A-FABP,FABP4
F1283	FABP7 Antibody [B3J10]	BLBP,Brain lipid binding protein,FABP7
E6614	FABPs ligand 6 (MF6)	FABPs ligand 6 (MF6) is a potent dual inhibitor of FABP5 and FABP7 with KD values of 874 nM and 20 nM, respectively. It rescues mitochondrial function and mitigates FABP5/FABP7-mediated injury, demonstrating potential therapeutic effects in multiple sclerosis (MS).
F1153	FACL4 Antibody [B15L22]	ACSL4,FACL4
F3425	Factor H Antibody [H24L2]
A5910	Factor XIIIa Rabbit Recombinant mAb	Factor XIIIa Rabbit Recombinant mAb detects endogenous levels of total Factor XIIIa.
A5928	FADD Rabbit Recombinant mAb	FADD Rabbit Recombinant mAb detects endogenous levels of total FADD.
S7371	Fadraciclib (CYC065)	Fadraciclib (CYC065) is a novel, orally available ATP-competitive inhibitor of CDK2/CDK9 kinases with IC50 of 5 nM and 26 nM, respectively.
S9519	Fadrozole (CGS16949A)	Fadrozole (CGS16949A) is a potent, selective, nonsteroidal inhibitor of aromatase with an IC50 of 4.5 nM and selectivity over other cytochrome P-450 enzymes.
F2606	FADS1 Antibody [D20F2]
E3733	Faeces Trogopterori Extract	Faeces Trogopterori Extract is derived from the faeces of the complex-toothed flying squirrel Trogopterus xanthipes Milne-Edwards.
E7119	Fagomine	Fagomine is a mild glycosidase inhibitor. The Ki of the iminosugar Fagomine is 4.8 μM, 39 μM, and 70 μM for Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast), respectively.
F3256	FAK Antibody [B11N6]
F0431	FAK Antibody [J10N20]
E2399	Falnidamol	Falnidamol (BIBX1382) is a selective inhibitor of epidermal growth factor receptor (EGFR), exerting anti-cancer role in human head and neck squamous cell carcinomas both in vitro and in vivo through suppressing mitogen-activated protein kinases (MAPKs) signaling.
F3721	FAM111A Antibody [E15D4]
S2467	Famciclovir	Famciclovir (BRL-42810) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.
S2078	Famotidine	Famotidine (MK208) is a histamine H2–receptor antagonist with IC50 of 0.6 mM, commonly used to treat heartburn, GERD, ulcers, and other digestive conditions.
S4327	Famprofazone	Famprofazone (Geodowin, FA, Famprofazonum) is a non-steroidal anti-inflammatory agent (NSAID) of the pyrazolone series. Famprofazone is an analgesic used for fever and pain relief.
F1154	FANCD2 Antibody [M9H23]
S3606	Fangchinoline	Fangchinoline, a bisbenzylisoquinoline alkaloid, is a novel HIV-1 inhibitor with pain-relieving, blood pressure-depressing, and antibiotic activities.
A5318	FAP1 Rabbit Recombinant mAb	FAP1 Rabbit Recombinant mAb detects endogenous level of total FAP1.
E8184	FAPI-4	FAPI-4 is a potent fibroblast activation protein (FAP) inhibitor for the targeting FAP. FAPI-4 can be used in cancer research. 68Ga-FAPI-4 PET/CT is a promising new diagnostic method for imaging various kinds of cancer, with good tumor-to-background contrast ratios.
S9285	Fargesin	Fargesin is a neolignan isolated from Magnolia plants. It is a potential β1AR antagonist through cAMP/PKA pathway.
A4052	Faricimab (Anti-Angiopoietin 2 & VEGF-A)	Faricimab is a humanized bispecific antibody that targets vascular endothelial growth factor A (VEGF-A) and angiopoietin-2 (Ang-2; Ang2; ANGPT2), key regulators of vascular leakage and inflammation. It is used to treat neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), and macular edema due to retinal vein occlusion, improving retinal vascular stability. M.W 146.41 kDa
D4015	Farletuzumab-MMAE	Farletuzumab-MMAE is an antibody-drug conjugate (ADC) composed of humanized anti-human folate receptor-alpha (FRα) and the cytotoxic agent monomethyl auristatin (MMAE) via a MC-Vc linker. It has a potent antitumor activity.
S4941	Farnesol	Farnesol is a natural sesquiterpene alcohol that is potent in treating antimetabolic disorders, anti-inflammation, showing antioxidant, anticancer, and antibiotic effects.
S6150	Farnesyl Acetate (mixture of isomers)	Farnesyl Acetate is a flavouring compound identified in foods such as blueberries.
E7204	Faropenem	Faropenem is a potent and orally active beta-lactam antibiotic. Faropenem demonstrates broad-spectrum in vitro antimicrobial activity against many gram-positive and -negative aerobes and anaerobes. Faropenem is resistant to hydrolysis by nearly all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Faropenem is developed as an oral proagent, faropenem medoxomil, for the research of respiratory tract infections.
S4847	Faropenem Sodium	Faropenem sodium is an orally active beta-lactam antibiotic that has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia.
S9552	Farrerol	Farrerol, an important bioactive constituent of rhododendron, exhibits broad activities such as anti-oxidative and anti-inflammatory effects.
S9721	Farudodstat	Farudodstat(LAS 186323,ASLAN003) is a potent and orally active inhibitor of DHODH (Dihydroorotate dehydrogenase) with IC50 of 35 nM for human DHODH enzyme activity. ASLAN003 impairs protein synthesis and induces the differentiation and apoptosis transcriptional program in acute myeloid leukemia (AML) cells via activation of AP-1 transcription factors.
F2091	Fascin Antibody [N3C10]
E1778	Fasentin	Fasentin, a potent glucose uptake inhibitor, inhibits GLUT-1/GLUT-4 transporters. Fasentin preferentially inhibits GLUT4 (IC50=68 μM) over GLUT1. Fasentin is a death receptor stimuli (FAS) sensitizer and sensitizes cells to FAS-induced cell death. Fasentin is also a tumor necrosis factor (TNF) apoptosis-inducing ligand sensitizer. Fasentin blocks glucose uptake in cancer cell lines and has anti-angiogenic activity.
E8161	Fasiglifam	Fasiglifam (TAK-875) is a potent, selective and orally bioavailable GPR40 agonist with EC50 of 72 nM.
S2637	Fasiglifam(TAK-875) Hemihydrate	Fasiglifam(TAK-875) Hemihydrate is a selective GPR40 agonist with EC50 of 14 nM in human GPR40 expressing CHO cell line, 400-fold more potent than oleic acid.
A5447	FASN Rabbit Recombinant mAb	FASN Rabbit Recombinant mAb detects endogenous level of total FASN.
S6248	Fasnall	Fasnall, a thiophenopyrimidine, is a selective fatty acid synthase (FASN) inhibitor that shows potent anti-tumor activity.
E1773	Fasoracetam (NS 105)	Fasoracetam (NS 105) is a metabotropic glutamate receptor activator with a potential to treat vascular dementia.
E2913	Fast Green FCF	Fast Green FCF (FD&C Green No. 3; Food green 3; C.I. 42053) is a sea green triarylmethane food dye. It is a dye used to stain proteins for IEF (isoelectric focusing) and SDS-PAGE. When bound to proteins, Fast Green FCF fluoresces near infrared (absorption maximum: 624 nm). Fast Green FCF staining is linear over a wider range of protein concentrations compared to Brilliant Blue R.
S1573	Fasudil HCl	Fasudil HCl, a potent and selective inhibitor of Rho kinase, displays less potent inhibiton over PKA, PKG, PKC and MLCK with Ki of 1.6, 1.6, 3.3, and 36 μM in cell-free assays, respectively. Fasudil is also a calcium channel blocker.
E2950	Fat Emulsion（20%）	Fat Emulsion（20%）is a safe fat emulsion that can be used as a nutritional supplement. Fat Emulsion（20%）inhibits the opening of the mitochondrial permeability transition pore and effectively protecting the heart from ischaemia-reperfusion injury. It has some potential to modulate the innate immune response.
S9785	Fatostatin	Fatostatin (125B11), a diarylthiazole derivative, is a specific inhibitor of Sterol regulatory element binding proteins (SREBPs) activation. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin suppresses growth and enhances apoptosis in cancer cells.
S8284	Fatostatin HBr	Fatostatin HBr is an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.
F2869	Fatty Acid Synthase Antibody [K10B23]	FASN,Fatty Acid Synthase,Fatty Acid Synthase/FASN
F0225	Fatty Acid Synthase Antibody [K9D22]	FASN,Fatty Acid Synthase,Fatty Acid Synthase/FASN
S7975	Favipiravir (T-705)	Favipiravir (T-705) is a potent and selective RNA-dependent RNA polymerase inhibitor, used to treat influenza virus infections.
E5928	FAZ-3532	FAZ-3532 is a potent inhibitor of G3BP that binds to G3BP1 with a Kd of 0.54 μM, inhibiting co-condensation of G3BP1, Caprin1, and RNA, and blocking stress granule formation in cells. It specifically targets the protein–protein interaction within the NTF2L domain of G3BP1 without affecting its dimerization or RNA-binding, making it a useful tool to study the immunological role of stress granules during viral infection.
S6291	FB23	FB23 is a potent and selective inhibitor of FTO demethylase with IC50 of 60 nM. FB23 directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.
S8837	FB23-2	FB23-2 is a potent and selective FTO inhibitor that directly binds to FTO and selectively inhibits FTO's N⁶-methyladenosine (m⁶A) demethylase activity with IC50 of 2.6 μM.
F2476	FBP1 Antibody [A7L2]	FBP1,FBP1/FBPase 1
E2846	FBPase-1 inhibitor-1	FBPase-1 inhibitor-1, an allosteric inhibitor of fructose-1,6-bisphosphatase (FBPase-1), exhibits similar potency (IC50 = 3.4 μM using MG; = 4.0 μM in the coupled format) in these two distinct assays of FBPase-1 activity.
F1544	Fbx32 Antibody [K16F17]
S8276	FCCP	FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone, Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone) is a potent uncoupler of oxidative phosphorylation in mitochondria that disrupts ATP synthesis by transporting protons across cell membranes.
L3800	FDA-approved & Passed Phase I Drug Library	A unique collection of 4210 drugs that are marketed around the world or have passed clinical phase 1 and can be used for high throughput screening (HTS) and high content screening (HCS).
L8000	FDA-approved Anticancer Drug Library	A unique collection of 1728 approved drugs with potential anticancer activity used for high throughput screening(HTS) and high content screening(HCS).
L1300	FDA-approved Drug Library	A unique collection of 3193 approved drugs and API included in pharmacopoeia for high throughput screening (HTS) and high content screening (HCS).
F2782	FDFT1 Antibody [H17C4]
S9689	FDI-6	FDI-6 (NCGC00099374) is an inhibitor of the Forkhead box protein M1 transcription factor (FOXM1) with IC50 of 22.5 μM.
S8795	FDL169	FDL169 is a CFTR corrector that is designed to fix and restore the function of the defective CFTR protein.
E4732	FDW028	FDW028 is a highly potent and selective inhibitor of FUT8. FDW028 demonstrates strong anti-tumor effects by promoting defucosylation and inducing lysosomal degradation of B7-H3 via the chaperone-mediated autophagy (CMA) pathway. Additionally, FDW028 suppresses the AKT/mTOR signaling pathway. FDW028 exhibits potent anti-Metastatic colorectal cancer (mCRC) activities.
S5092	Febantel	Febantel (Rintal, Combotel, Oratel, Bay Vh 5757, Negabot Plus) is a prodrug that is metabolized to fenbendazole and oxfendazole, which are undoubtedly the active parasiticides.
S1547	Febuxostat	Febuxostat (TMX 67, TEI-6720) is a selective xanthine oxidase inhibitor with K_i of 0.6 nM.
F3844	FECH Antibody [M13C12]
S2736	Fedratinib (TG101348)	Fedratinib (SAR302503, TG101348) is a selective inhibitor of JAK2 with IC50 of 3 nM in cell-free assays, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3. Fedratinib also inhibits FMS-like tyrosine kinase 3 (FLT3) and RET (c-RET) with IC50 of 15 nM and 48 nM, respectively. Fedratinib has potential antineoplastic activity. Fedratinib inhibits proliferation and induces apoptosis. Phase 2.
E5818	Fedratinib hydrochloride hydrate	Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate, SAR 302503 hydrochloride hydrate) is a small-molecule, ATP-competitive inhibitor of JAK2 with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. It induces cancer cell apoptosis and has potential for efficacious treatment of JAK2V617F-associated myeloproliferative disease.
S1330	Felbamate	Felbamate (Felbatol, ADD-03055,W-554) is an anticonvulsant drug used in the treatment of epilepsy; NMDAR antagonist.
S1885	Felodipine	Felodipine (CGH-869) is a selective L-type Ca²⁺ channel blocker with IC50 of 0.15 nM.
P1047	Felypressin Acetate	Felypressin-Acetate is a non-catecholamine vasoconstrictor that is chemically associated to vasopressin, the posterior pituitary hormone.
F4164	FEN-1 Antibody [P22D7]
A5805	FEN1 Rabbit Recombinant mAb	FEN1 Rabbit Recombinant mAb detects endogenous levels of total FEN1.
E5886	FEN1-IN-1	FEN1-IN-1 (Compound 1) is an inhibitor of Flap endonuclease 1 (FEN1), binding to its active site and inhibiting activity partly by coordinating with Mg²⁺ ions. By blocking FEN1, it initiates a DNA damage response, activating the ATM checkpoint pathway, histone H2AX phosphorylation, and FANCD2 ubiquitination in mammalian cells.
S3397	FEN1-IN-4	FEN1-IN-4 (FEN1 Inhibitor C2, JUN93587, Compound 2) is an inhibitor of human flap endonuclease-1 (hFEN1) with IC50 of 30 nM for hFEN1-336Δ.
S5517	Fenamic acid	Fenamic acid (N-Phenylanthranilic acid, 2-(Phenylamino)benzoic acid, 2-Anilinobenzoic acid, Diphenylamine-2-carboxylic acid) serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid.
S2468	Fenbendazole	Fenbendazole(Fenbendazol,Phenbendasol) is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL.
E7984	Fenbendazole-d3	Fenbendazole-d3 is a deuterium labeled Fenbendazole. Fenbendazole-d3 is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53.
S4526	Fenbufen	Fenbufen (Lederfen, CL-82204) is an orally active phenylalkanoic derivative with anti-inflammatory, analgesic and antipyretic activity. It is a non-steroidal anti-inflammatory drug.
S5379	Fenchyl Alcohol	Fenchyl Alcohol is used as a flavoring agent to provide a pine, herbal, lemon, or floral taste to food and drink.
S5279	Fendiline hydrochloride	Fendiline hydrochloride is the hydrochloride salt form of Fendiline, which is an L-type calcium channel blocker and also a specific inhibitor of K-Ras plasma membrane targeting with no detectable effect on the localization of H- and N-Ras.
S8421	Fenebrutinib (GDC-0853)	Fenebrutinib (GDC-0853) is a potent, selective, and non-covalent bruton's tyrosine kinase (BTK) inhibitor with an Ki value of 0.91 nM for Btk with >100-fold selectivity over 3 off-targets (Bmx :153-fold, Fgr: 168-fold, Src:131-fold).
S5702	Fenipentol	Fenipentol (1-phenylpentan-1-ol, 1-Phenyl-1-pentanol, 1-Phenylpentanol) is a member of benzenes and stimulates plasma secretion & exocrine pancreatic secretion.
S1794	Fenofibrate	Fenofibrate is a compound of the fibrate class and fibric acid derivative. Fenofibrate is a selective agonist of PPARα with EC50 of 30 μM. Fenofibrate binds to and inhibits cytochrome P450 epoxygenase (CYP)2C with IC50 of 0.2 μM, 0.7 μM and 9.7 μM for CYP2C19, CYP2B6 and CYP2C9, respectively. Fenofibrate induces autophagy.
S4527	Fenofibric acid	Fenofibric acid (NSC 281318, Trilipix, FNF acid) is a fibrate that acts as a lipid-lowering agent, decreasing low-density lipoprotein cholesterol and triglycerides.
S2089	Fenoldopam	Fenoldopam (SKF 82526) is a selective dopamine-1 (DA1) receptor agonist with natriuretic/diuretic properties with EC50 of 55.5 nM in stimulating cAMP accumulation in LLC-PK1 cells, which is more potent than DA .
S4618	Fenoldopam mesylate	Fenoldopam (SKF 82526, Corlopam) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.
S1823	Fenoprofen Calcium	Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.
S3027	Fenoprofen calcium hydrate	Fenoprofen calcium hydrate(Fenoprofen calcium salt dihydrate,Feprona dihydrate,Progesic dihydrate) is a non-steroidal anti-inflammatory drug (NSAID).
S5769	Fenoterol	Fenoterol (Phenoterol) is a β2 adrenoreceptor agonist with bronchodilator activity.
S5768	Fenoterol hydrobromide	Fenoterol hydrobromide (Phenoterol) is the the hydrobromide salt of fenoterol, a β2 adrenoreceptor agonist with bronchodilator activity.
S5233	Fenretinide	Fenretinide is a synthetic derivative of retinoic acid that has a broad-spectrum of cytotoxic activity against primary tumor cells, cell lines, and/or xenografts of various cancers (including neuroblastoma). Fenretinide (4-hydroxy(phenyl)retinamide; 4-HPR) is a synthetic derivative of retinoic acid, fenretinide can bind to retinoic acid receptor (RAR) and retinoid X receptor (RXR) at concentrations necessary to induce cell death.
S4090	Fenspiride HCl	Fenspiride(Decaspiride) is a bronchodilator with anti-inflammatory properties, inhibiting phosphodiesterase 4 and phosphodiesterase 3 activities with logIC50 values of 4.16 and 3.44, respectively, in human isolated bronchi.
S2031	Fenticonazole Nitrate	Fenticonazole Nitrate(Lomexin,REC 15-1476,Falvin) is an azole antifungal agent.
E3297	Fenugreek Seed Extract	Fenugreek Seed Extract is extracted from the seeds of Trigonella foenum-graecum, which acts as an antibacterial and anticancer agent.
F3007	Fer Antibody [N22A1]
E3166	Fermented Blank Bean Extract	Fermented Blank Bean Extract is extracted from the fermented Phaseolus vulgaris L., and aids in protection of the human digestive tract, mainly the colon.
E3137	Fermented Soybean Extract	Fermented Soybean Extract is obtained from Fermented soybean, which shows high antioxidant activity.
E4962	Ferric citrate	Ferric citrate (Iron(III) citrate, Zerenex) is a Class 1 ferroptosis inducer and a safe, effective oral phosphate binder that increases iron stores and reduces the need for IV iron and erythropoiesis-stimulating agents while maintaining hemoglobin. It is approved for treating hyperphosphatemia in dialysis-dependent chronic kidney disease (CKD) and for iron deficiency anemia.
F3878	Ferritin Heavy Chain Antibody [N2N7]
A5901	Ferritin Light Chain Rabbit Recombinant mAb	Ferritin Light Chain Rabbit Recombinant mAb detects endogenous levels of total Ferritin Light Chain.
A5654	Ferritin Rabbit Recombinant mAb	Ferritin Rabbit Recombinant mAb detects endogenous level of total Ferritin.
L6400	Ferroptosis Compound Library	A unique collection of 724 compounds used for exploring the mechanism of ferroptosis which is an iron-dependent form of non-apoptotic cell death.
S7243	Ferrostatin-1 (Fer-1)	Fer-1 (Ferrostatin-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM.
S6449	Ferrous Bisglycinate	Ferrous bisglycinate (Iron glycinate) is a chelate that is used as a source of dietary iron. It acts as both a chelate and a nutritionally functional.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!
S6406	Ferrous fumarate	Ferrous fumarate (Iron(II)) is the fumarate salt form of the mineral iron and is used in treatment of iron deficiency anemia.
S9221	Ferulaldehyde	Ferulaldehyde (Coniferaldehyde, Ferulyl aldehyde) is a natural intermediate of polyphenol metabolism of intestinal microflora.
S2300	Ferulic Acid	Ferulic Acid (Fumalic) is a hydroxycinnamic acid and a type of organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong. Ferulic acid is a novel fibroblast growth factor receptor (FGFR) inhibitor with IC50s of 3.78 μM and 12.5 μM for FGFR1 and FGFR2, respectively.
S5451	Ferulic acid methyl ester	Ferulic acid methyl ester (Methyl Ferulate, Methyl 4'-hydroxy-3'-methoxycinnamate) is a lipophilic derivative of ferulic acid, which is a hydroxycinnamic acid that is abundant in plants. It shows the strongest antioxidant activity and can protect against inflammation and cancer.
E7955	FeTCPP	FeTCPP (Iron(III) meso-Tetra(4-carboxyphenyl)porphine chloride) is a metallic porphyrin compound formed by the coordination of a central iron ion (Fe3+) with four 4-carboxyphenylporphyrins (TCPP). FeTCPP can be used as a catalyst for catalytic, electrochemical, photochemical and biomedical research. FeTCPP has high photocatalytic performance for p-nitrophenol under visible light. FeTCPP also has peroxisase-like activity, which is used in bionic catalysis research.
P1243	Fetuin, Fetal Bovine Serum	Fetuin, Fetal Bovine Serum, a prevalent protein found in fetal bovine plasma, is the bovine equivalent of human α2HS glycoprotein (α2HS), commonly used as a supplement in various serum-free media. It inhibits trypsin activity and enhances cellular attachment, growth, and differentiation in culture systems.
E3766	Feverfew Extract	Feverfew Extract is obtained from Tanacetum parthenium L., which is a herbal remedy used for preventing attacks of migraine.
E7323	Fevipiprant	Fevipiprant (QAW039, NVP-QAW039) is s an orally active, selective, reversible prostaglandin D2 (DP2) receptor antagonist with an Kd value of 1.14 nM. Fevipiprant has the potential for the research of bronchial asthma.
S2801	Fexagratinib (AZD4547)	Fexagratinib (AZD4547,ABSK 091) is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM in cell-free assays, weaker activity against FGFR4, VEGFR2(KDR), and little activity observed against IGFR, CDK2, and p38. Phase 2/3.
S6413	fexaramine	Fexaramine is a potent, selective farnesoid X receptor (FXR) agonist with an EC50 of 25 nM and it displays no activity at hRXRα, hPPARα, hPPARγ, hPPARδ, mPXR, hPXR, hLXRα, hTRβ, hRARβ, mCAR, mERRγ and hVDR receptors.
S2600	Fexinidazole	Fexinidazole (HOE-239, Fexinidazole Winthrop) is a 5-nitroimidazole derivative. Fexinidazole is a DNA synthesis inhibitor and the only, all-oral agent for Human African Trypanosomiasis(HAT or sleeping sickness).
E7049	Fexofenadine	Fexofenadine (MDL-16455, Terfenadine carboxylate) is a non anticholinergic and non sedative second-generation antagonist of histamine (H1) receptor. It can be used in research to treat allergic disorders by suppressing eosinophilia and systemic anaphylaxis, especially in allergic rhinitis and chronic urticaria.
S3208	Fexofenadine HCl	Fexofenadine (MDL 16455A) inhibits histamine H1 receptor with IC50 of 246 nM.
E0109	Fezolinetant	Fezolinetant (ESN-364) is a potential antagonist of the neurokinin 3 receptor (NK3R). It interrupts pulsatile lh secretion and moderates levels of ovarian hormones throughout the menstrual cycle.
S8899	FF-10101	FF-10101 is a novel irreversible FLT3 inhibitor with ic50 of 0.20 nM and 0.16 nM for FLT3 (WT) and FLT3(D835Y), respectively.
S7979	FG-2216	FG-2216 is a potent, and orally active HIF prolyl 4-hydroxylase inhibitor with IC50 of 3.9 μM for PHD2. Phase 2.
F0331	FGF Receptor 1 Antibody [C5C14]	FGF Receptor 1,FGFR1
F0779	FGF Receptor 2 Antibody [C16A22]	Bek/FGFR2,FGF Receptor 2,FGFR2
F3422	FGF1 Antibody [D5D10]	Acidic FGF,FGF1
F1541	FGF21 Antibody [H23F24]
E0621	FGFR1/DDR2 inhibitor 1	FGFR1/DDR2 inhibitor 1 is an inhibitor of fibroblast growth factor receptor 1 (FGFR1) and discoidin domain receptor 2 (DDR2).
A5777	FGFR3 Rabbit Recombinant mAb	FGFR3 Rabbit Recombinant mAb detects endogenous levels of total FGFR3.
E8065	FGFR4-IN-1	FGFR4-IN-1 is a potent inhibiotr of FGFR4 with IC50 of 0.7 nM.
E8028	FGH10019	FGH10019 is a novel sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM.
S7450	FH1	FH1 is a small molecule, which promotes differentiation of iPS-derived hepatocytes.
E1859	FHD-609	FHD-609 acts as a selective inhibitor and degrader of BRD9 protein (bromodomain-containing protein 9). FHD-609 targets ncBAF and can be used in research of various cancers involving mutations in a BAF complex subunit.
E1711	FHT-1015	FHT-1015 is a potent, small-molecule, allosteric inhibitor of SMARCA4/SMARCA2 ATPase with IC50 values ≤10 nM. FHT-1205 decreases PD1+TIM3+ cells and cytokine expression in vivo.
E1709	Fialuridine	Fialuridine(FIAU, DRG-0098, NSC 678514) is a nucleoside analog with antiviral activity. It blocks DNAsynthesis in human cytomegalovirus and hepatitis B, as well as herpes simplex.
F3066	Fibrillarin Antibody [B24C20]
F3589	Fibrillarin Antibody [C16M7]
F2821	Fibrinogen γ chain Antibody [D18L17]
E7857	Fibrinogen-Binding Peptide	Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin.
E7161	Fibronectin	Fibronectin is a glycoprotein found in blood and cells, serving as a biomarker of tissue injury and playing a key role in promoting wound repair. It also binds to extracellular matrix proteins like collagen, fibrin, and heparan sulfate proteoglycans, with elevated plasma levels observed in conditions such as inflammation, trauma, exbiting a potential tool for research.
F0886	Fibronectin/FN1 Antibody [C12E22]	Fibronectin,Fibronectin, cell binding domain,Fibronectin, Cellular,Fibronectin/FN1
F2734	Fibulin 5 Antibody [L20L7]
A5798	Fibulin 5 Rabbit Recombinant mAb	Fibulin 5 Rabbit Recombinant mAb detects endogenous levels of total Fibulin 5.
A2661	Ficlatuzumab (Anti-HGF / SF)	Ficlatuzumab (Anti-HGF / SF) is a monoclonal antibody (McAb) targeting human hepatocyte growth factor (HGF). It inhibits c-Met receptor-mediated cancer cell proliferation, migration, and invasion and can be used to treat head and neck squamous cell carcinoma (HNSCC). MW :150 KD.
E4035	Ficoll(R) 400	Ficoll(R) 400 (sucrose-epichlorohydrin copolymer) is a macromolecular crowder that plays a pivotal role in promoting liquid-liquid phase separation (LLPS) of proteins. It is currently utilized in the isolation of serum and peripheral blood mononuclear cells (PBMC) from the whole blood of Parkinson's disease (PD) patients.
E3724	Ficus carica Extract	Ficus Carica Extract is obtained from Ficus carica Linn. (Moraceae), which has been used in traditional medicine for a wide range of ailments related to digestive, endocrine, reproductive, and respiratory systems.
E3735	Ficus hirta Vahl Extract	Ficus Hirta Vahl Extract is derived from Ficus hirta Vahl. (Wuzhimaotao), which possesses hepatoprotective, antibacterial, and anti-inflammatory bioactivities and improves memory function of AD mice.
S9682	FICZ	FICZ (6-Formylindolo[3,2-b]carbazole) is a potent agonist of aryl hydrocarbon receptor (AhR) that is efficiently metabolized by AHR-regulated cytochrome P4501 enzymes.
E7937	Fidarestat	Fidarestat (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease.
E0081	FIDAS-3	FIDAS-3 effectively competes against S-adenosylmethionine (SAM) for methionine sadenosyltransferase 2A (MAT2A) binding . FIDAS-3 has anticancer activities by inhibiting the expression of oncogenes. FIDAS-3 is a stilbene derivative and is a potent Wnt inhibitor with an IC50 of 4.9 μM for MAT2A.
E4639	FIDAS-5	FIDAS-5 is a potent and orally active inhibitor of methionine S-adenosyltransferase 2A (MAT2A) with an IC50 value of 2.1 μM, respectively. FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding. FIDAS-5 also demonstrates anticancer activity.
S4227	Fidaxomicin	Fidaxomicin is a narrow spectrum macrocyclic antibiotic that inhibits RNA polymerase sigma subunit.
S7715	FIIN-3	FIIN-3 is an irreversible inhibitor of FGFR with an IC50 of 13.1, 21, 31.4, and 35.3 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.
F1638	Filamin A Antibody [F14A18]	Filamin 1,Filamin A,FLNA
E7550	Filanesib	Filanesib (ARRY-520) is a selective and noncompetitive kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity.
S7354	Filanesib hydrochloride	Filanesib (ARRY-520) hydrochloride is a kinesin spindle protein (KSP) inhibitor that blocks the separation of centrosomes and assembly of spindles in the early stage of cell mitosis, and cell proliferation.
S0843	Filastatin	Filastatin, a long-lasting inhibitor of Candida albicans filamentation, inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay.
S7605	Filgotinib (GLPG0634)	Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Phase 2.
E8153	Filipin complex	Filipin complex is a potent polyene macrolide antifungal antibiotic that integrates into membranes, sequestering cholesterol into complexes. Its treatment reduces PRRSV genome copies by 61% and lowers the PRRSV titer. It also acts as a fluorescent histochemical stain prone to autooxidation, commonly used in diagnosing Niemann-Pick Disease Type C (NP-C), a neurodegenerative lysosomal storage disorder. Researchers also employ it to study unesterified cholesterol distribution in cell and animal models of neurodegenerative diseases like NP-C and Sanfilippo syndrome (MPS IIIA).
S7402	Filipin III	Filipin III is a polyene macrolide antibiotic derived from Streptomyces filipinensis. It exhibits antifungal activity against Candida utilis with an MIC of 0.3 mg/L and Saccharomyces cerevisiae with an MIC of 0.4 mg/L by interacting with membrane sterols, leading to alterations in membrane structure. Filipin III has a strong affinity for cholesterol and exhibits fluorescent properties, with the potential to be used as a valuable tool for detecting and quantifying cholesterol in biological membranes.
E7669	Filorexant	Filorexant (MK-6096) is an orally bioavailable potent and selective reversible antagonist of OX1 and OX2 receptor(<3 nM in binding).
S4975	Fimasartan	Fimasartan (Kanarb) is a non-peptide angiotensin II receptor antagonist (ARB) with noncompetitive, insurmountable binding with the AT1 receptor. It is used for the treatment of hypertension and heart failure.
S2759	Fimepinostat (CUDC-907)	CUDC-907 is a dual PI3K and HDAC inhibitor for PI3Kα and HDAC1/2/3/10 with IC50 of 19 nM and 1.7 nM/5 nM/1.8 nM/2.8 nM, respectively. CUDC-907 induces cell cycle arrest and apoptosis in breast cancer cells. Phase 1.
S1197	Finasteride	Finasteride (MK-906) is a potent, reversible inhibitor of the rat type 1 5 alpha-reductase with K_i of 10.2 nM, used in the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB).
E3366	Fineleaf Schizonepeta Herb Extract	Fineleaf Schizonepeta Herb Extract is extracted from the leaves of Schizonepeta, which is used as a traditional medicine with antipyretic, anti-inflammatory, analgesic, and hemostatic effects.
S9702	Finerenone	Finerenone (FIN, BAY 94-8862) is a highly selective and orally available nonsteroidal antagonist of mineralocorticoid receptor (MR) with IC50 of 18 nM. Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.
S5950	Fingolimod (FTY-720)	Fingolimod (FTY-720) is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis.
S5002	Fingolimod (FTY720) HCl	Fingolimod (FTY720, Fingolimod Hydrochloride) HCl is a S1P antagonist with IC50 of 0.033 nM in K562, and NK cells. Please use saline solution rather than PBS for dilutions. PBS may cause precipitation.
E8104	Fingolimod phosphate	Fingolimod phosphate (FTY720 phosphate) is an orally active sphingosine 1-phosphate (S1P) receptor agonist. Fingolimod phosphate can promote the neuroprotective effects of microglia. Fingolimod phosphate can be used for the research of multiple sclerosis and neurologic diseases.
E1244	FINO2	FINO2 is a potent ferroptosis inducer which inhibits GPX4 activity. FINO2 causes widespread lipid peroxidation.
F0729	FIP200 Antibody [L13C2]
E7942	Fipexide	Fipexide, a parachloro-phenossiacetic acid derivative, is an orally active nootropic that improves cognitive performance through dopaminergic neurotransmission. It reduces striatal adenylate cyclase activity, enhancing memory and cognitive function. It also acts as a chemical inducer in callus formation, shoot regeneration, and Agrobacterium infection.
S6478	Fipexide hydrochloride	Fipexide (hydrochloride) is a psychoactive drug of the piperazine class.
S7321	FIPI	FIPI (5-Fluoro-2-indolyl deschlorohalopemide), a derivative of halopemide, is a potent and selective inhibitor of phospholipase D with IC50 of 25 nM and 20 nM for PLD1 and PLD2, respectively.
S5366	Fipronil	Fipronil (Fluocyanobenpyrazole, Termidor) is a recalcitrant phenylpyrazole-based pesticide used for flea/tick treatment and termite control that is distributed in urban aquatic environments via stormwater and contributes to stream toxicity.
E8183	Firategrast	Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist. Firategrast reduces trafficking of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity.
F2045	Firefly Luciferase Antibody [H5E21]	Firefly Luciferase,Luciferase
E5881	Firmonertinib	Firmonertinib is an oral, brain-penetrant, mutant-selective inhibitor of EGFR. It targets a broad spectrum of EGFR mutations, including exon 20 insertions and the T790M resistance mutation. Firmonertinib is being developed as a first-line treatment for patients with advanced non-small cell lung cancer (NSCLC) harboring EGFR exon 20 insertions.
E0500	Firocoxib (ML 1785713)	Firocoxib (ML 1785713) is a cyclooxygenase (COX)-2 inhibitor and a nonsteroidal anti-inflammatory drug. In vitro firocoxib inhibits COX-1 and COX-2 with an IC50 of 7.5 mM and 0.13 mM respectively in feline blood.
S8893	Firsocostat (GS-0976, ND-630)	Firsocostat (GS-0976, ND-630) is a reversible inhibitor of acetyl CoA carboxylase (ACC) with IC50s of 2.1 nM,6.1 nM for hACC1 and hACC2,respectively.
S8503	Fisogatinib (BLU-554)	Fisogatinib (BLU-554) is a potent, highly-selective, oral FGFR4 inhibitor with an IC50 value of 5 nM. The IC50s for FGFR1-3 is 624-2203 nM.
H2536	FITC Bcl-2 Antibody [100]
G2086	FITC Bcl-2 Antibody [BCL/10C4]
H2986	FITC BCRP1 Antibody [5D3]	Breast cancer resistance protein (BCRP1), also known as placenta-specific ATP-binding cassette (ABC) protein (ABCP) or ABC G-subfamily member 2 (ABCG2), or mitoxantrone resistance protein (MXR), is a member of the ATP-binding cassette superfamily of drug transporters thought to be involved in multi-drug resistance in human neoplastic disease. ABCG2 is expressed in drug-resistant breast, colon and gastric cancer and fibrosarcoma cancer cell lines and in blast cells from patients with acute myeloid leukemia (AML). Normal tissues that express the ABCG2 protein include placental syncytiothrophoblasts, mammary ducts and lobules, epithelium in the large intestine and colon, venous and capillary epithelium and bile canalicular membrane of the live
G0406	FITC BrdU Antibody [BU20A]	Bromodeoxyuridine (5-bromo-2-deoxyuridine, BrdU) is a synthetic nucleoside that is an analogue of thymidine. BrdU is commonly used in the detection of proliferating cells in living tissues, and can be incorporated into the newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication. Antibodies specific for BrdU can then be used to detect the incorporated chemical, thus indicating cells that were actively replicating their DNA. Binding of the antibody requires denaturation of the DNA, usually by exposing the cells to acid or heat.
G4561	FITC CCL2/MCP-1 Antibody [2H5]
G0796	FITC CD103/Integrin αE Antibody [2E7]	CD103, also known as ITGAE or Integrin alpha E, is a molecule that non-covalently associates with integrin beta 7 to form a heterodimeric integral membrane protein. This protein is part of the integrin family, characterized by an alpha chain and a beta chain. Specifically, CD103 includes a 150 kDa alpha chain and a 120 kDa beta chain, with the alpha integrin undergoing post-translational cleavage in the extracellular domain to yield disulfide-linked heavy and light chains. CD103 is primarily expressed on mucosa-associated T lymphocytes, intraepithelial lymphocytes (IELs), and activated cells, as well as a subset of TGF beta-1 cells. It is preferentially found in human intestinal IELs, where it plays a role in adhesion and may serve as an ac
G3451	FITC CD105/Endoglin Antibody [MJ7/18]	CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up-regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation-associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
G0256	FITC CD105/Endoglin Antibody [SN6]	CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
G4051	FITC CD117/c-Kit Antibody [2B8]	KIT (c-KIT), also known as CD117, is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth. c-Kit is expressed in hematopoietic stem cells, germ cell
H4381	FITC CD117/c-Kit Antibody [ACK2]
G2071	FITC CD11b+CD11c Antibody [OX42]	CD11b (Integrin αM) and CD11c (Integrin αX) are α-chain integrins that belong to the β2 integrin family. They are primarily expressed on myeloid cells, including monocytes, macrophages, dendritic cells, and neutrophils. These integrins play key roles in cell adhesion, migration, phagocytosis, and immune regulation through interactions with ligands such as iC3b, ICAM-1, and fibrinogen. CD11b is highly expressed on monocytes and neutrophils, whereas CD11c is widely used as a marker for dendritic cells.
G0091	FITC CD11c Antibody [N418]	CD11, along with CD18, form a heterodimer adhesion molecule. In particular, CD11 is composed of CD11a, CD11b and CD11c. CD11a is a leukocyte marker that is expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils and eosinophils. CD11b is primarily expressed by monocytes, macrophages, natural killer cells, some B and T-cells, and granulocytes. CD11c is expressed in monocytes, macrophages, natural killer cells, some granulocytes and less so in a subset of lymphocytes.
G0451	FITC CD127 Antibody [A7R34]	CD127, also known as the Interleukin-7 receptor alpha chain (IL-7Ralpha), is a type I glycoprotein with a molecular weight of 75-80 kDa. It forms a multi-functional receptor complex with CD132, the common gamma chain, to create the IL-7 receptor (IL-7R), which is crucial for lymphopoiesis. The active IL-7 receptor is an alpha/gamma chain heterodimer, where the gamma chain also associates with the interleukin-2 receptor and primarily activates signal transduction, while the alpha chain determines specific signaling events through its association with cytoplasmic signaling molecules. CD127 is expressed by immature B cells through the early pre-B stage, thymocytes during various stages of development, and most mature T cells, with transient do
G0826	FITC CD140a/PDGFRα Antibody [APA5]	PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
H0331	FITC CD161 Antibody [HP-3G10]	CD161, also known as NKR-P1A, is a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. CD161 exists as a homodimer and is prominently expressed on natural killer (NK) and NKT cells, where it is proposed to regulate the function of both cell types. CD161 is also found on T cell subsets, including T regulatory cells (Tregs), memory/effector CD4+ T cells, and CD8+ T cells. Th17 cells have been demonstrated to co-express CD161, as surface IL-17A+ cells are contained within the CD161+ fraction of CD4 T cells, so that CD161 (in combination with CCR6) is often used as a marker for enrichment of Th17 cells.
G0901	FITC CD169 Antibody [MOMA-1]	CD169 is a lectin-like receptor expressed by certain populations of macrophages including marginal zone metallophils of the spleen, subcapsular macrophages of lymph nodes and stromal macrophages in bone marrow. CD169 is a ~185 kDa sialic acid binding receptor containing 17 immunoglobulin-like domains. Expression of CD169 can be induced on macrophages in culture by a serum factor and further modulated by cytokine exposure.
H1291	FITC CD18 Antibody [YFC118.3]	CD18 is an integral membrane glycoprotein of ~95 kDa, also known as the beta 2 chain of the LFA-1 complex. CD18 non-covalently links to CD11a, b, or c molecules to form the heteromeric LFA-1 complex. CD18 acts as the receptor for ICAM-1 and is important for cell adhesion and cell-cell interactions.
G0601	FITC CD184/CXCR4 Antibody [2B11]	CXCR4 (Fusin, LESTR, HUMSTR) is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains, and functions as a co-receptor for X4 HIV-1 entry into CD4⁺ cells. CXCR4 has been proved to be the co-receptor for HIV-2's binding to CD4 through envelope glycoprotein gp 120 and promotes Env-mediated fusion of the virus. In other cases, CXCR4 can even function as the only receptor for HIV-2's binding to the CD4 host cells. CXCR4 is the receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. CXCR4 acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced c
G1711	FITC CD1d Antibody [1B1]	CD1d is a heavy chain associated with Beta 2 microglobulin on cortical thymocytes. Beta 2 microglobulin independent expression of CD1d has also been demonstrated on human intestinal epithelial cells. CD1d is the sole group 2 member of the CD1 family of major histocompatibility (MHC) like glycoproteins. The CD1d gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1
G1936	FITC CD204 Antibody [2F8]
G4126	FITC CD23 Antibody [B3B4]	CD23 is a 45 kDa glycoprotein that serves as a low-affinity receptor for IgE, playing a crucial role in regulating IgE responses and B cell activation. It is expressed on mature B cells, mantle zone B cells, follicular dendritic cells, and at lower levels on T cells, NK cells, Langerhans cells, and platelets. CD23 expression is upregulated upon B cell activation, and its soluble forms are biologically active, acting as potent mitogenic factors. CD23 is strongly expressed on Epstein-Barr virus (EBV)-transformed B lymphoblasts and is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells. It is also detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some centroblastic/centrocytic lym
G0271	FITC CD24 Antibody [M1/69]	CD24 is a 35-50 kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed on a variety of cell types, including erythrocytes, thymocytes, peripheral lymphocytes, and cells of the myeloid lineage. It is variably glycosylated, resulting in heterogeneity in molecular mass across different cell lineages, which can affect antibody staining levels on lymphocyte populations. In the context of B-cell development, CD24 is expressed from the pro-B-cell stage in the bone marrow through to mature, surface Ig-positive B cells, with very low or negative expression on plasma cells. It is also present on the majority of B-lineage acute lymphoblastic leukemias, B-cell chronic lymphocytic leukemias (CCLs), and B-cell non-Hodgkin's lymphomas. CD2
G1381	FITC CD244/2B4 Antibody [A24P17]
H3286	FITC CD266 Antibody [ITEM-4]
H0166	FITC CD27 Antibody [O323]	CD27 (TNFRSF7) is a cell surface homodimer of ≥55 kDa subunits that provides co-stimulatory signaling in support of T cell (TCR) and B cell (BCR) receptors. Compared to CD28, whose TCR co-stimulatory signal can trigger cell proliferation, CD27 signaling promotes cell survival and differentiation to effector/memory stages. CD27 may be shed following interaction with its ligand CD70, which is typically expressed on activated dendritic cells, T cells, and B cells. In B cells, CD27 is a phenotypic marker for memory B cells and has also been included among markers for identifying B regulatory cells (Bregs), which regulate CD4+ T cell proliferation and Foxp3/CTLA-4 expression in Treg cells.
G1096	FITC CD278 Antibody [C398.4A]
G0421	FITC CD279/PD-1 Antibody [J43]	Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. Despite its p
H3571	FITC CD282/TLR2 Antibody [TL2.1]
H0691	FITC CD284/TLR4 Antibody [HTA125]	TLR4 is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This receptor is most abundantly expressed in placenta, and in the myelomonocytic subpopulation of leukocytes. Mammalian cells respond to LPS by activating TLR4. TLR4 belongs to the multi-protein complex of the lipopolysaccharide (LPS) receptor, containing CD14, LY96, and TLR4, and is involved in signal transduction events induced by LPS found in most gram-negative bacteria. TLR4 aids in the recognition of pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents and
G0571	FITC CD29/ITG-β1 Antibody [C13M2]	CD29, also known as ITGB1 or Integrin Subunit Beta 1, is a 110 kDa cell surface glycoprotein widely expressed by various cells, including all leukocytes. It forms non-covalently linked heterodimers with at least six different alpha integrins (CD49a-f), creating VLA-1 through VLA-6 complexes, as well as with CD51. These alpha-beta integrin heterodimers mediate a range of cellular responses, including adhesion, trafficking, proliferation, and differentiation. CD29-containing integrins bind to extracellular matrix proteins such as collagen, laminin, fibronectin, and vitronectin. Some integrins also interact with cellular receptors like VCAM-1 and MadCAM-1. CD29 plays a crucial role in immune cell trafficking from blood to tissue, particularly
H3586	FITC CD303/BDCA-2 Antibody [AC144]
G4096	FITC CD326/EpCAM Antibody [G8.8]	Ep-CAM (epithelial adhesion molecule, epithelial specific antigen, ESA), also known as CD326, is a transmembrane glycoprotein expressed in the epithelium with a molecular weight of approximately 40 kDa, which functions as an epithelial cell adhesion molecule. Ep-CAM functions as a homotypic calcium-independent cell adhesion molecule, and has a direct impact on cell cycle, proliferation and metabolism of epithelial cells and fibroblasts due to its ability to rapidly induce the proto-oncogene c-myc and the cell cycle regulating genes cyclin A and E. Ep-CAM mediates Ca2+-independent homotypic interactions. Formation of Ep-CAM-mediated adhesions have a negative regulatory effect on adhesions mediated by classic cadherins, which may have strong
G3061	FITC CD335/NKp46 Antibody [29A1.4]
G0121	FITC CD34 Antibody [RAM34]	CD34 is a highly glycosylated monomeric with a molecular weight range of 111-115 kDa surface protein that is present on many stem cell populations. CD34 is a stem cell marker although its expression on human hematopoietic stem cells is reversible. CD34 may serve as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions. CD34 is possibly an adhesion molecule with a putative role for mediating the attachment of stem
G0076	FITC CD44 Antibody [IM7]	CD44 cell surface antigen is a 100 kDa type 1 transmembrane glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential. CD44 is expressed by hematopoietic, non-hematopoietic cells, epithelial tissu
G0016	FITC CD45 Antibody [30-F11]	CD45, also known as Leukocyte Common Antigen (LCA). CD45 is expressed by all hematopoietic cells excluding mature erythrocytes and platelets. The cytoplasmic portion of CD45 has tyrosine phosphatase enzymatic activity and plays an important role in activation of lymphocytes.
G0346	FITC CD45.1 Antibody [A20]	CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. Besides t
G0301	FITC CD45.2 Antibody [104]	CD45.2 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45.2 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45.2 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. Besides
G0106	FITC CD45R/B220 Antibody [RA3-6B2]	CD45R (PTPRC) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. CD45 contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. CD45 is specifically expressed in hematopoietic cells and has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists in multiple isoforms as a result of alternative splicing, and these isoforms di
H3031	FITC CD46 Antibody [MEM-258]
H1426	FITC CD47 Antibody [B6H12]
G3481	FITC CD5 Antibody [53-7.3]	CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.
H1726	FITC CD52 Antibody [YTH34.5]	The CD52 antigen is a remarkably small but heavily glycosylated peptide attached to the cell surface membrane via a GPI link. The apparent molecular mass of the native antigen on SDS-PAGE is 25-29 kDa, considerably reduced following N-glycanase treatment. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable. Humanized versions of CAMPATH-1 specific antibodies may be used for the research treatment of a range of lymphoid malignancies.
G0241	FITC CD62L/L-Selectin Antibody [MEL-14]	The human CD62L is a 74-95 kDa glycoprotein member of the selectin family of adhesion receptors. L-Selectin is comprised of an aminoterminal C-type lectin binding domain, an epidermal growth factor-like domain, two short consensus repeat (SCR) sequences homologous to those found in complement binding proteins, a short spacer region, a transmembrane region and a short cytoplasmic region. Human CD62L (L-Selectin) is constitutively expressed on all classes of leukocytes including lymphocytes (except a substantial population of memory T cells), monocytes and polymorphonuclear cells.
G0481	FITC CD68 Antibody [ED1]	CD68 antibody recognizes the rat ED1 antigen, a heavily glycosylated protein of ~90 -110 kDa, also known as rat CD68. The ED1 antigen is expressed on most macrophages populations, as well as on monocytes and is considered as a pan-macrophage marker in the rat. ED1 is expressed predominantly on the lysosomal membrane and lightly on the cell surface. The expression of ED1 antigen being predominantly cytoplasmic, flow cytometry results are improved by the use of a membrane permeabilization procedure, such as Leucoperm, prior to staining.
G0496	FITC CD68 Antibody [FA-11]	CD68 is considered a pan-macrophage marker, predominantly expressed on the intracellular lysosomes of tissue macrophages/monocytes, including Kupffer cells, microglia, histiocytes and osteoclasts, and is expressed to a lesser extent by dendritic cells and peripheral blood granulocytes. CD68 is expressed by many tumor types including some B cell lymphomas, blastic NK lymphomas, melanomas, granulocytic (myeloid) sarcomas, hairy cell leukemias, and renal, urinary and pancreatic tumors, and can be used to demonstrate the presence/localization of macrophages.
G0211	FITC CD80/B7-1 Antibody [16-10A1]	CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunct
H1741	FITC CD88 Antibody [S5/1]	Mouse anti Human CD88 antibody, recognizes the C5a receptor (C5aR) CD88, which is predominantly expressed on cells of the myeloid lineage. It was raised against a synthetic peptide comprising the N-terminal extracellular domain of the C5aR (met1-Asn31) and has recently been shown to recognise the heptameric peptide (D15DKDTLD21). It has been shown to inhibit the binding of C5a to its receptor.
G0001	FITC CD8a Antibody [53-6.7]	CD8 (Cluster of differentiation 8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation. CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer of CD8alpha and CD8beta, where it functions as a co-receptor, along with T cell receptor (TCR), for major histocompatibilty complex class I (MHC-I) molecules; whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules. CD8 exists on the cell surface, where the CD8alpha chain is essential for binding to MHC-I. CD8 is also expressed on a subset of T cells, NK cells, monocytes and dendritic cells as disulfide-linked homodimers of CD8alpha. Ligation of MH
G0736	FITC CD90.1/Thy-1.1 Antibody [HIS51]	CD90 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. It is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts. Thy 1 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
G2626	FITC CD93 Antibody [AA4.1]	CD93 (also known as AA4.1, C1qRp) is a cell-surface glycoprotein and type I membrane protein originally identified as a myeloid cell marker. Although previously considered a C1q receptor, CD93 is now recognized for its roles in intercellular adhesion and the clearance of apoptotic cells. Its intracellular tail interacts with moesin, linking CD93 to the cytoskeleton and cytoskeletal remodeling.
G2416	FITC Dectin-1 Antibody [2A11]
G0061	FITC F4/80 Antibody [BM8]
H0766	FITC FCER1A Antibody [AER-37 (CRA1)]	Fc epsilon RI alpha, also known as FcεRIα, is a subunit of the high-affinity receptor for IgE, primarily expressed on mast cells and basophils. Its expression is upregulated by the presence of IgE. FcεRIα forms a tetrameric complex with one beta and two gamma subunits, which are essential for signal transduction. The beta and gamma subunits contain immunoreceptor tyrosine-based activation motifs (ITAMs). The FcεRI complex plays a crucial role in triggering IgE-mediated allergic reactions. When allergen-bound IgE molecules bring together two or more high-affinity IgE receptors, it leads to the release of mediators such as histamine, which are responsible for allergy symptoms. This process couples allergens and mast cells to initiate inflamma
G0751	FITC FCER1A Antibody [MAR-1]	Fc epsilon RI alpha, also known as FceR1 alpha, is a subunit of the high-affinity receptor for IgE, primarily expressed on mast cells and basophils. Its expression is upregulated by the presence of IgE. Fc epsilon RI alpha forms a tetrameric complex with one beta and two gamma subunits, which are essential for signal transduction. The beta and gamma subunits contain immunoreceptor tyrosine-based activation motifs (ITAMs). The Fc epsilon RI complex plays a crucial role in triggering IgE-mediated allergic reactions. When allergen-bound IgE molecules bring together two or more high-affinity IgE receptors, it leads to the release of mediators such as histamine, which are responsible for allergy symptoms. This process couples allergens and mast
G0031	FITC FOXP3 Antibody [FJK-16s]	FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-alle
G0046	FITC FOXP3 Antibody [PCH101]	FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-alle
H0391	FITC Granzyme B Antibody [GB11]	Granzyme B is a member of the granzyme serine protease family, and is found in the granules of cytotoxic T cells and NK cells. Granzyme B has been described as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation, and CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells. Granzyme B is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells. The receptor involved in this process has been identified as mannose 6-phosphate receptor which functions as a death receptor for Granzyme B during cytotoxic T cell-induced ap
G1816	FITC Helios Antibody [22F6]
G3736	FITC HER2/ErbB2 Antibody [H24A7]	The ErbB2 (HER2) proto-oncogene encodes a 185 kDa transmembrane, receptor-like glycoprotein with intrinsic tyrosine kinase activity. While ErbB2 lacks an identified ligand, ErbB2 kinase activity can be activated in the absence of a ligand when overexpressed and through heteromeric associations with other ErbB family members. Amplification of the ErbB2 gene and overexpression of its product are detected in almost 40% of human breast cancers. Binding of the c-Cbl ubiquitin ligase to ErbB2 at Tyr1112 leads to ErbB2 poly-ubiquitination and enhances degradation of this kinase. ErbB2 is a key therapeutic target in the treatment of breast cancer and other carcinomas and targeting the regulation of ErbB2 degradation by the c-Cbl-regulated proteolyt
H2746	FITC HLA-G Antibody [87G]
H1456	FITC Human CD10 Antibody [HI10a]	CD10, also known as Neutral Endopeptidase (NEP), Enkephalinase, Atriopeptidase, and Neprilysin, is a 100 kDa type II transmembrane glycoprotein encoded by the MME (membrane metallo-endopeptidase) gene. CD10 has neutral endopeptidase activity and is also referred to as the Common Acute Lymphoblastic Leukemia Antigen (CALLA). It is expressed on a wide variety of normal and neoplastic cell types, including granulocytes, bone marrow stromal cells, a subset of B-cell progenitors, germinal center B cells, and fibroblasts. CD10 is a cell surface metalloendopeptidase that inactivates several signaling molecules, playing a significant regulatory role in the nervous, immune, and other systems.
H0451	FITC Human CD107a Antibody [H4A3]	CD107a, also known as Lysosomal-associated membrane protein 1 (LAMP-1), is a ~110 kDa type I transmembrane protein that is heavily glycosylated and widely expressed by cells primarily on the luminal surface of their lysosomes. It is also expressed on the surface of activated platelets, activated lymphocytes, cytotoxic T cells and NK cells, and some tumor cell lines, including U937 and KG1a. LAMP-1 can serve as a ligand for E-selectin-mediated cell adhesion. LAMP-1 and LAMP-2 (CD107b) are carriers for poly-N-acetyllactosamines and are able to display sialyl Le[x] termini.
H0376	FITC Human CD117 Antibody [104D2]	CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells.
H3316	FITC Human CD11a Antibody [HI111]	This antibody specifically binds to CD11a, the 180 kDa integrin α chain. This type I transmembrane glycoprotein associates with CD18 (integrin β2) to form the heterodimeric glycoprotein CD11a/CD18. This heterodimer is also known as the lymphocyte (leukocytes) function associated antigen-1 (LFA-1) that is expressed on all leukocytes. LFA-1 is an adhesion molecule involved in lymphocyte and granulocyte functions. LFA-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligand, and the intracellular adhesion molecule-1 (ICAM-1), CD54. Other ligands are ICAM-2 (CD102) and ICAM-3 (CD50). Purified Mouse Anti-Human CD11a antibody also cross reacts with all leukocytes of baboon, and both rhesus and cynomolgus ma
H0076	FITC Human CD11b Antibody [CBRM1/5]	CD11b, a 165-170 kDa type I transmembrane glycoprotein also known as αM integrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils as well as adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen and factor X.
H0061	FITC Human CD11b Antibody [ICRF44]	CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αM integrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.
H0136	FITC Human CD11c Antibody [3.9]	CD11c is a 145–150 kDa type I transmembrane glycoprotein also known as integrin αx and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.
H0481	FITC Human CD127 Antibody [HIL-7R-M21]	CD127 is a 60–90 kDa glycoprotein, also known as the IL-7 receptor alpha (IL-7Rα) subunit. The IL-7 receptor complex is a heterodimer composed of CD127 and the common gamma chain (γc, CD132), shared by other cytokine receptors (IL-2R, IL-4R, IL-9R, IL-15R, and IL-21R). CD127 is expressed on thymocytes, T- and B-cell progenitors, mature T cells, and some lymphoid and myeloid cells. In vitro experiments show the expression of CD127 is down-regulated following T cell activation. Studies indicate that the IL-7 receptor plays an important role in the proliferation and differentiation of mature T cells. Recently, it has been shown that low surface expression of CD127, in combination with intermediate to high surface expression of CD25, the α chai
H3331	FITC Human CD13 Antibody [WM15]	CD13, also known as aminopeptidase N, is a 150 kDa type II integral membrane glycoprotein. It serves as the cellular receptor for human coronavirus 229E, which can cause upper respiratory tract infections. CD13 is expressed on GM-progenitor cells, granulocytic and monocytic cells, and mast cells, but is absent on lymphocytes, platelets, and erythrocytes. It plays a role in the metabolism of various regulatory peptides.
H0991	FITC Human CD133/PROM1 Antibody [AC133]
H3466	FITC Human CD134/OX40 Antibody [Ber-ACT35 (ACT35)]
H3796	FITC Human CD137 Antibody [4B4-1]	CD137 is a 39 kD transmembrane protein also known as 4-1BB. It is expressed on activated T cells. CD137 is a type I membrane protein and a member of the tumor necrosis factor receptor superfamily. CD137 appears to be important for T cell proliferation and survival, and induces monocyte activation through its interaction with 4-1BB ligand.
H0811	FITC Human CD138 Antibody [44F9]
H0181	FITC Human CD14 Antibody [M5E2]	CD14 is a 53–55 kDa glycosylphosphatidylinositol (GPI)-anchored single-chain glycoprotein expressed at high levels on monocytes, macrophages, and neutrophils. CD14 is a multifunctional receptor and is constitutively expressed on the surface of mature monocytes and macrophages. It serves as a high-affinity receptor for lipopolysaccharide (LPS) and binds LPS in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute-phase serum protein. CD14 also exists in a soluble form (sCD14) and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. The soluble sCD14 is important for neutralizing allochthonous lipopolysaccharides by reconstituted lipoprotein particles and can discriminate structural dif
H1681	FITC Human CD144/VE-cadherin Antibody [55-7H1]	Cadherin-5, a member of the cadherin family of calcium-dependent adhesion molecules, is also known as CD144 or VE-Cadherin. CD144 is expressed on endothelial cells in vivo and in vitro. It may play a role in the organization of lateral endothelial junctions and in the control of permeability properties of vascular endothelium.
H1036	FITC Human CD146 Antibody [P1H12]	CD146, also known as MCAM, MUC18, or Mel-CAM, is a 118 kDa transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is strongly expressed by blood vessel endothelium and smooth muscle. CD146 is also found on angioblasts, mesenchymal stem cells, melanoma cells, intermediate trophoblasts, and a subset of activated T cells. CD146 is widely used as a marker for endothelial cells and plays a key role in studies of angiogenesis, cancer progression, and vascular biology.
H0661	FITC Human CD150/SLAM Antibody [A12 (7D4)]
H1366	FITC Human CD155/PVR Antibody [SKII.4]
H2806	FITC Human CD158b/j Antibody [DX27]
H1126	FITC Human CD16 Antibody [3G8]	CD16a is a ~50–65 kDa type I transmembrane glycoprotein encoded by FCGR3A (Fc fragment of IgG receptor IIIa), which belongs to the immunoglobulin superfamily. CD16a is also known as Fc-gamma RIII-alpha (FcγRIIIA or FcRIIIa) and is expressed on natural killer (NK) cells, activated monocytes, macrophages, γδ T cells, immature thymocytes, and mast cells. CD16a binds immune-complexed or aggregated IgG and associates with CD247/TCRζ in NK cells and FcεRIγ chains in phagocytes and mast cells to transduce intracellular signals. CD16a functions in antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses including phagocytosis, cytokine production, or mediator release. CD16b is a ~48 kDa glycophosphatidylinositol (GPI)-
H3496	FITC Human CD163 Antibody [GHI/61]	CD163 is also known as Scavenger receptor cysteine-rich type 1 protein M130 (M130), Hemoglobin scavenger receptor and Macrophage-associated antigen. CD163 is a 110-130 kDa transmembrane glycoprotein. CD163 is a monocyte/macrophage-restricted antigen expressed on the majority of tissue macrophages and peripheral blood monocytes. CD163 belongs to the scavenger receptor superfamily. Its expression on monocytes is upregulated upon cellular activation. CD163 expression reportedly changes on monocytes and macrophages as these cells differentiate. This finding suggests a role for this molecule in the differentiation and/or regulation of monocyte and macrophage function. CD163 may play a role in the clearance and endocytosis of hemoglobin and hapto
H2821	FITC Human CD166/ALCAM Antibody [3A6]	CD166, also known as Activated Leukocyte Cell Adhesion Molecule (ALCAM) and the CD6 ligand, is a 100–105 kDa transmembrane glycoprotein belonging to the immunoglobulin superfamily. It consists of an immunoglobulin-like extracellular domain, a transmembrane region, and a short cytoplasmic tail. CD166 is expressed on neurons, activated T cells, activated monocytes, epithelial cells, and fibroblasts. It plays a key role in mediating adhesion interactions, particularly between thymic epithelial cells and CD6+ cells during intrathymic T-cell development.
H3511	FITC Human CD172a/SIRPα Antibody [15-414]
H0001	FITC Human CD19 Antibody [HIB19]	CD19 is a 95 kDa type I transmembrane glycoprotein expressed during all stages of B-cell maturation and differentiation, except on plasma cells. It is also present on follicular dendritic cells but not found on T cells or normal granulocytes. CD19 functions as a signal transduction molecule that regulates B cell development, activation, proliferation, and differentiation. It associates with complement receptor 2 (CD21), TAPA-1 (CD81), Leu 13, and/or MHC class II to form a signal transduction complex on the surface of B cells.
H1021	FITC Human CD195 Antibody [2D7/CCR5]	CCR5, also known as CD195, is a seven transmembrane-spanning G protein-coupled receptor (GPCR) that belongs to the beta chemokine receptor family. It is expressed on a subset of T lymphocytes (CD3⁺CD45RO⁺CD95⁺). CCR5 plays a key role in regulating lymphocyte chemotaxis, activation, and transendothelial migration during inflammation by responding to at least three chemokines: RANTES (Regulated upon Activation, Normal T-cell Expressed and Secreted), MIP-1 (Macrophage Inflammatory Protein-1), and MCP-2 (Monocyte Chemoattractant Protein 2). Additionally, CCR5 serves as a coreceptor for macrophage-tropic HIV-1 on CD4⁺ T cells, which is critical for viral entry and transmission. Individuals with partial (heterozygous) or complete (homozygous) del
H1576	FITC Human CD1a Antibody [HI149]	CD1a is a type I transmembrane glycoprotein. The 49 kDa CD1a polypeptide is associated with β2-microglobulin. CD1a is expressed on cortical thymocytes, dendritic cells and Langerhans cells. CD1a has structural similarities to the MHC class I antigen, and plays a role in antigen presentation.
H1591	FITC Human CD1c Antibody [L161]	CD1c, also known as R7 or M241, is a 43 kD member of the five CD1 antigens (CD1a-e) in humans. The CD1 molecules are type I glycoprotein with structural similarities to MHC class I and are non-covalently associated with β2-microglobulin, belonging to the Ig superfamily. CD1c is expressed on cortical thymocytes, Langerhans cells, dendritic cells, and a subset of B cells. It has been reported that CD1c is also expressed on mature T cells in a tightly regulated manner. CD1c is involved in antigen-presentation of glycolipids. It may also act in T cells as an immune regulatory molecule.
H1156	FITC Human CD20 Antibody [2H7]	CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
H3556	FITC Human CD200 Antibody [OX-104]
H2086	FITC Human CD203c/E-NPP3 Antibody [NP4D6]
H2296	FITC Human CD21 Antibody [B-ly4]	CD21 is a receptor for the C3d complement fragment and for Epstein-Barr virus (EBV). CD21 is expressed on mature B cells, follicular dendritic cells, and some epithelial cells. It is also weakly expressed on the subset of mature T cells and thymocytes. CD21 plays a role in B-cell activation and proliferation. It may also play a role in modulating the function of T cells in the immune response to infections by lymphotropic viruses. Recently, CD21 was found to be part of a large complex containing CD19, CD81, and possibly other molecules. This mAb also cross-reacts with a major subset of, but not all, peripheral blood CD20+ lymphocytes of baboon, and both rhesus and cynomolgus macaque monkeys. A subset of CD3+ cells is also CD21+.
H2371	FITC Human CD218a/IL-18Rα Antibody [H44]
H3346	FITC Human CD22 Antibody [HIB22]
H1201	FITC Human CD226 Antibody [DX11]
H0871	FITC Human CD23 Antibody [M-L233]	CD23 is a type II membrane glycoprotein that is expressed by B cells, monocytes, macrophages, eosinophils, platelets and dendritic cells. CD23 mediates IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. Soluble CD23 (sCD23) can be released by CD23-positive cells as a result of proteolytic cleavage of membrane CD23. Larger fragments of sCD23 (e.g., 25-37 kDa) retain their IgE-binding capacity whereas smaller fragments (ie, ≤ 12 kDa) do not. Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types.
H1051	FITC Human CD235a Antibody [GA-R2 (HIR2)]	CD235a is also known as Glycophorin A (GYPA, GPA, GLPA), Sialoglycoprotein alpha, MN sialoglycoprotein, or PAS-2. CD235b is also known as Glycophorin B (GYPB, GPB, GLPB), Sialoglycoprotein delta, SS-active sialoglycoprotein, or PAS-3. CD235a and CD235b are type I transmembrane sialoglycoproteins expressed on human erythrocytes, erythroid precursor cells, and certain leukemic cell types. CD235a carries blood group M and N antigens, whereas CD235b contains S, s, and U antigens. Glycophorins may play a role in preventing cell agglutination. The antibody against CD235a/b is useful for the identification and characterization of erythrocytes, certain myeloid leukemic cell types, and for studies of erythroid development and infectious diseases inv
H0316	FITC Human CD24 Antibody [ML5]	CD24, also known as CD24A, signal transducer CD24, small cell lung carcinoma cluster 4 antigen, or BA-1, is a 35-70 kDa glycophosphatidylinositol (GPI)-linked glycoprotein. Its glycosylation pattern is highly variable and cell-type dependent. CD24 is expressed on neutrophils, eosinophils, dendritic cells, neural cells, epithelial cells, muscle cells, and many types of cancer cells. CD24 functions as an adhesion receptor. Several different ligands have been identified for CD24, including CD62P (P-selectin), which is expressed on activated platelets and activated endothelium. CD24 is variably expressed on all B lineage cells, except plasma cells, and can play a role in regulating the activation, proliferation, or differentiation of these cell
H1606	FITC Human CD244/2B4 Antibody [C1.7]
H4246	FITC Human CD25 Antibody [M-A251]	The CD25 antigen is also known as the human low-affinity interleukin-2 receptor α chain (IL-2Rα) and the Tac antigen. The CD25antigen is present on a subset of peripheral blood lymphocytes. Antigen density increases on phytohemagglutinin (PHA)-, concanavalin A (Con A)-, and CD3-activated T lymphocytes; T lymphocytes from mixed lymphocyte cultures; and HTLV-infected T-lymphocyte leukemia lines, for example, HUT-102. Recombinant IL-2 blocks the binding of CD25 to PHA-activated T lymphocytes. CD4+/CD25+ regulatory T cells might directly regulate the function of responsive T cells. The CD25antibody is composed of mouse IgG1 heavy chains and kappa light chains
H3361	FITC Human CD26 Antibody [BA5b]
H2161	FITC Human CD268/BAFF-R Antibody [11C1]	B cell-activating factor receptor (BAFF-R) is a 19 kD type III membrane protein. It belongs to TNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) which binds to TACI and BCMA as well. The interaction of BAFF with BAFF-R promotes NF-κB activation and plays predominant roles in B-cell maturation and survival as well as costimulates T cell activation and proliferation. TRAF3 is a BAFF-R intracellularly associated protein, which negatively regulates BAFF-R-mediated NF-κB activation.
H4111	FITC Human CD271/NGFR Antibody [ME20.4]	CD271, also known as p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR, and NGFR, is a type I transmembrane protein with a MW of 75 kD. It is expressed by many cell types including neurons, Schwann cells, mesenchymal stem/stromal cells, follicular dendritic cells and melanocytes. The extracellular portion contains four TNFR-Cys repeats that form the binding domain for its ligands (NGF, BDNF, NTF3, and NTF4). The intracellular portion of CD271 contains a death domain, which interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9, to promote cell apoptosis, and to regulate cell differentiation and neurogenesis.
H1546	FITC Human CD272/BTLA Antibody [MIH26]
H2446	FITC Human CD275/B7-H2/ICOSL Antibody [2D3]
H0436	FITC Human CD279/PD-1 Antibody [EH12.2H7]	Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 (B7-H1) and PD-L2 (B7-DC) are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
H4096	FITC Human CD28 Antibody [CD28.2]	CD28 is a 44 kDa homodimeric transmembrane glycoprotein expressed on most mature T cells, thymocytes, and plasma cells. It acts as a costimulatory receptor, binding to CD80 and CD86 ligands, and plays a crucial role in T cell-B cell interactions. CD28 is believed to initiate and regulate a distinct signal transduction pathway that is separate from those stimulated by the TCR complex. The binding of CD28 to its ligands can also influence immune responses, including the production of IL-2 and changes in intracellular calcium concentrations.
H1756	FITC Human CD294/CRTH2 Antibody [BM16]	CD294, also known as CRTH2, is a seven-transmembrane protein coupled with heterotrimeric G proteins. CRTH2 is the prostaglandin D2 receptor and is expressed by Th2 cells, eosinophils, and basophils. CD294 prevents the apoptosis of Th2 cells and mediates the chemotaxis of CRTH2 expressing cells to the sites of allergic inflammation, such as the asthmatic lung.
H4276	FITC Human CD3 Antibody [OKT-3]	CD3ε is one of five polypeptide chains that combine to form the TCR complex. CD3ε is expressed on T lymphocytes, NK-T cels, and to varying degrees on developing thymocytes. CD3 plays roles in TCR signaling, T lymphocyte activation, and antigen recognition.
H4351	FITC human CD3 Antibody [UCHT1]
H1501	FITC Human CD304 Antibody [12C2]
H0241	FITC Human CD31 Antibody [AC128]	CD31, a 120–140 kDa single-chain transmembrane glycoprotein, is present on virtually all monocytes, platelets, and granulocytes. CD31 is also expressed by lymphocyte subsets. During maturation of CD4+ T cells, the expression of CD31 changes: CD4+ recent thymic emigrants (RTEs) express CD31 in contrast to central naive T cells. CD31 is highly expressed on endothelial cells, especially at their juncture, and is also known EndoCAM. CD31 also known as Platelet endothelial cell adhesion molecule-1 (PECAM-1), a member of the immunoglobulin superfamily, widely expressed on endothelial cells, platelets, monocytes, granulocytes, hematopoietic stem cells, and undifferentiated embryonic stem cells. Structurally, its extracellular domain consists of si
H0226	FITC Human CD31 Antibody [WM59]	CD31 (PECAM-1), also known as GPIIA' or EndoCAM, is a 130 kDa type I transmembrane glycoprotein belonging to the Ig gene superfamily. It is widely expressed on platelets, monocytes, granulocytes, NK cells, T cell subsets, and in high amounts on endothelial cells. CD31 functions as a vascular endothelial cell adhesion molecule, playing a critical role in the transendothelial migration of leukocytes during inflammatory responses. It is also involved in thrombosis, angiogenesis, and wound healing. The antibody against PECAM-1 binds to an epitope near extracellular domain 2 of CD31.
H1396	FITC Human CD314/NKG2D Antibody [1D11]	CD314, also known as NKG2D or KLRK1, is a 42 kDa type II transmembrane glycoprotein and a member of the C-type lectin family. It is expressed on human NK cells, as well as on virtually all TCR γ/δ+ and CD8+ TCR α/β+ T cells. NKG2D functions as an activating receptor that binds strongly to several ligands, including MICA, MICB, and ULBP-1, -2, and -3, which are expressed by different target cell types. Unlike other natural cytotoxicity receptors (NCR), NKG2D is not restricted to NK cells. It plays a critical role in natural cytotoxicity, aiding normal NK cells in attacking a variety of tumor or normal target cells. NKG2D can complement the role of NCR in tumor cell lysis, and combined masking of both NCR and NKG2D can lead to a complete inhi
H0916	FITC Human CD33 Antibody [WM53]	CD33, also known as Sialic acid-binding Ig-like lectin 3 (Siglec-3), gp67, or p67, is a 67 kDa type I transmembrane glycoprotein expressed on monocytes, activated T cells, myeloid progenitors, and mast cells. CD33 is absent on normal platelets, lymphocytes, erythrocytes, and hematopoietic stem cells. This glycoprotein can reportedly function as a sialic acid-dependent cell adhesion molecule. This function can be modulated by endogenous sialoglycoconjugates when CD33 is expressed on the membrane.
H3616	FITC Human CD335/NKp46 Antibody [9E2]
H1066	FITC Human CD36 Antibody [CB38 (NL07)]
H3646	FITC Human CD366 Antibody [F38-2E2]	CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.
H0856	FITC Human CD38 Antibody [HIT2]	The CD38 antigen is also known as T10, ADP-ribosyl cyclase 1, and cyclic ADP ribose hydrolase 1. CD38 is a 45 kDa type II single-chain transmembrane glycoprotein present on thymocytes, activated T cells, and terminally differentiated B cells (plasma cells). It is also expressed by monocytes, macrophages, dendritic cells, NK cells, myeloid and erythroid precursors, and some epithelial cells. CD38 functions as an ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose, a Ca²⁺-mobilizing second messenger. This intracellular calcium plays an important role in cell signaling pathways leading to cellular growth, apoptosis, and differentiation. CD38 binds to CD31, contributing to lymphocyte adhesion to endothelial cells.
H3376	FITC Human CD39 Antibody [A1]	CD39 is an integral membrane protein with two transmembrane domains in humans. It exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late a
H0046	FITC Human CD4 Antibody [L200]	CD4 is a 56 kDa transmembrane glycoprotein expressed on the T-helper/inducer subset of peripheral blood lymphocytes in humans. It is primarily found on CD3-positive, CD8-negative T cells and does not react with B- or NK-cell markers. In baboons, CD4 is expressed on lymphocytes and weakly on monocytes. The distribution of CD4 on lymphocytes is similar between humans and these non-human primates.
H0031	FITC Human CD4 Antibody [RPA-T4]	CD4 is a 56 kDa transmembrane glycoprotein expressed on the T-helper/inducer subset of normal human peripheral blood lymphocytes. The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex
H0556	FITC Human CD40 Antibody [5C3]	CD40 is a 45–48 kDa type I transmembrane glycoprotein primarily expressed on B lymphocytes, though it is absent on terminally differentiated B cells. It is also found on endothelial cells, basal epithelial cells, certain epithelial cell carcinomas, follicular dendritic cells, macrophages, fibroblasts, keratinocytes, and CD34+ hematopoietic progenitor cells. CD40 plays a critical role in B-cell growth, proliferation, and differentiation, including immunoglobulin isotype switching. Engagement of CD40, particularly in the presence of IL-4 or costimulation with anti-µ or anti-CD20 antibodies, can promote B-cell proliferation.
H0886	FITC Human CD41a Antibody [HIP8]	CD41a, also known as Integrin αIIb or Platelet GPIIb, forms a calcium-dependent complex with CD61 (β3 integrin or GPIIIa) that is normally expressed on platelets and megakaryocytes. The CD41/CD61 complex serves as a receptor for fibrinogen, fibronectin, and von Willebrand factor, mediating platelet adhesion and aggregation. Blocking CD41 can completely inhibit ADP-, epinephrine-, and collagen-induced platelet activation, and partially inhibit ristocetin- and thrombin-induced activation.
H4036	FITC Human CD42b Antibody [HIP1]	CD42b is also known as the Platelet glycoprotein Ib alpha chain that is encoded by the GP1BA gene. CD42b is disulfide bonded to CD42c to form a 170 kDa heterodimer, GPIb. GPIb forms a noncovalent complex with CD42a and CD42d (CD42 complex) that is expressed on platelets and megakaryocytes. The CD42 complex serves as the von Willebrand Factor (vWF) surface receptor involved in the adhesion of platelets to the subendothelium of damaged vascular walls. This antibody inhibits the ristocetin-dependent binding of vWF to platelets and partially inhibits collagen-induced aggregation.
H0106	FITC Human CD45 Antibody [5B1]	CD45 also known as protein tyrosine phosphatase receptor type C (PTPRC), is a large type I transmembrane glycoprotein, is an evolutionary highly conserved receptor protein tyrosine phosphatase exclusively expressed on all nucleated cells of the hematopoietic system. It is characterized by the expression of several isoforms, specific to a certain cell type and the developmental or activation status of the cell. CD45 is one of the key players in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency results in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also plays a significant role in autoimmune diseases and can
H0091	FITC Human CD45 Antibody [HI30]	CD45 is encoded by the PTPRC (Protein tyrosine phosphatase receptor type C) gene. CD45, also known as the leukocyte common antigen (LCA), is a member of the protein tyrosine phosphatase (PTP) family. It is present on all human leukocytes including lymphocytes, monocytes, granulocytes, eosinophils, and thymocytes. CD45 is absent from circulating erythrocytes, platelets, or mature erythroid cells of bone marrow and non-hemopoietic tissues.
H0736	FITC Human CD45RA Antibody [HI100]	CD45RA, a 220 kDa isoform of the human leukocyte common antigen, is expressed on approximately 40–50% of peripheral CD4+ T cells, 50% of peripheral CD8+ T cells, and on a portion of B cells and monocytes. The CD45RA antigen is expressed by naïve and activated T cells. CD45RA-specific antibodies are useful for the study of the suppressor/inducer subpopulation of CD4+ lymphocytes.
H4006	FITC Human CD45RO Antibody [UCHL1]	CD45RO is a 180 kDa isoform of the CD45 molecule, also known as the Leukocyte Common Antigen. It is a type I transmembrane glycoprotein with cytoplasmic protein tyrosine phosphatase activity involved in signal transduction. Unlike other CD45 isoforms, CD45RO lacks the amino acid sequences encoded by the variable exons A, B, and C. It is expressed on most thymocytes, activated T cells, memory T cells, granulocytes, and monocytes, and on a subset of resting T cells. CD45RO and CD45RA mark largely distinct populations within resting peripheral T cells, demonstrating functional and phenotypic heterogeneity within CD4 and CD8 T cell subsets. CD45RO also interacts with CD22.
H0526	FITC Human CD49f Antibody [GoH3]	CD49f, also known as the integrin α6 chain, is a ~150 kDa type I transmembrane glycoprotein that belongs to the integrin alpha chain family of extracellular matrix and cell adhesion receptors. The integrin α6 subunit associates with the integrin β1 chain (CD29) to form VLA-6, and with the integrin β4 chain (CD104) to form the integrin α6β4 complex, also known as the laminin and kalinin receptor. CD49f is expressed mainly on T cells, monocytes, platelets, epithelial cells, endothelial cells, perineural cells, and trophoblasts of the placenta. Antibodies against CD49f can block the binding of integrin α6 to laminin P1 and E8 fragments.
H1246	FITC Human CD54 Antibody [HA58]	CD54, also known as Intercellular Adhesion Molecule 1 (ICAM-1), is an 85-110 kDa type I transmembrane glycoprotein that belongs to the immunoglobulin supergene family. A soluble form of CD54 can also be found in biological fluids. CD54 is expressed on endothelial cells, as well as on both resting (weak) and activated (moderate) lymphocytes and monocytes. It serves as a ligand for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). The CD54 adhesion molecule plays a key role in inflammatory and immune responses, as well as in neoplasia.
H4261	FITC Human CD56/NCAM-1 Antibody [B159]	CD56 is a heavily glycosylated adhesion protein that is present on a subpopulation of peripheral blood large granular lymphocytes that demonstrate natural killer activity. CD56 is also expressed on a subset of T cells but is not expressed on myeloid cells, erythrocytes or B cells. This antigen is a pan-NK-cell marker. CD56 is virtually identical to an isoform of the neural cell adhesion molecule (NCAM), a structure mediating homotypic and heterotypic cell-cell interactions.
H3961	FITC Human CD61 Antibody [VI-PL2]	CD61 is a 105 kDa transmembrane glycoprotein that is also known as integrin β3 and platelet glycoprotein IIIa (GPIIIa or GP3A). It is expressed on platelets, megakaryocytes, osteoclasts and endothelia. Integrin β3 associates with gpIIa (CD41) to form the CD41/CD61 complex which mediates platelet adhesion and aggregation. CD61 also associates with CD51 to form the CD51/CD61 complex (vitronectin receptor). CD61 appears to bind to fibrinogen, fibronectin, vWF, vitronectin, and thrombospondin to mediate cell adhesion.
H0286	FITC Human CD62L Antibody [DREG-56]	CD62L (L-selectin) is a cell surface glycoprotein expressed on neutrophils, monocytes, T- and B-lymphocyte subsets, and NK cells. CD62L functions as a lymphocyte homing receptor, playing a key role in the migration of lymphocytes to peripheral lymph nodes via high endothelial venules (HEV).
H1321	FITC Human CD63 Antibody [H5C6]	CD63 is a 53 kDa, type III lysosomal glycoprotein that belongs to the tetraspan transmembrane 4 superfamily (TM4SF). It is expressed on activated platelets, monocytes, and macrophages, and is also known by several other names, including LIMP, gp55, melanoma-associated antigen ME491, Pltgp40, and LAMP-3. CD63 is widely expressed on the surface and in the cytoplasm of various hematopoietic cells (such as monocytes and macrophages) as well as non-hematopoietic cells (including endothelium, fibroblasts, osteoclasts, and smooth muscle cells). It plays a key role in mediating cellular adhesion and motility.
H0511	FITC Human CD68 Antibody [Y1/82A]	CD68, also known as Scavenger receptor class D member 1 (SCARD1), Macrosialin, or GP110, is a 110 kDa type I transmembrane glycoprotein primarily localized in cytoplasmic granules of monocytes, macrophages, dendritic cells, granulocytes, myeloid progenitor cells, and reportedly, a subset of CD34-positive hematopoietic bone marrow progenitor cells. CD68 belongs to the sialomucin family and functions as a scavenger receptor, capable of binding and internalizing oxidized low-density lipoproteins (LDL). Antibodies targeting CD68 are commonly used in studies of myeloid cell development and function.
H0271	FITC Human CD69 Antibody [FN50]
H3991	FITC Human CD7 Antibody [M-T701]	CD7 is a 40 kDa type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily. The CD7 antigen is also known as Leu-9, TP41, Tp40, GP40, and T-cell leukemia antigen. It is expressed on thymocytes, T cells, pre-B cells, and NK cells. CD7 is present in reduced density on monocytic cells and cell lines. Functional studies demonstrate that crosslinking of the CD7 can induce transmembrane calcium flux in T cells.
H1876	FITC Human CD70 Antibody [113-16]
H3931	FITC Human CD71 Antibody [M-A712]	This antibody specifically binds to CD71 which is also known as the transferrin receptor (TFR). This type II transmembrane glycoprotein is expressed on cells as a disulfide-linked homodimer comprised of 95 kDa monomers. CD71 is expressed on activated lymphocytes, monocytes, macrophages, erythroid progenitors, brain endothelium, and most proliferating cells. CD71 is not expressed on resting lymphocytes and is upregulated during lymphocyte responses to antigens or mitogens. Through an endocytic pathway, the transferrin receptor mediates cellular iron uptake by binding and internalizing iron that is bound to transferrin. After releasing iron within the low pH endosomal environment, transferrin and its receptor can be recycled to the cell surfa
H0361	FITC Human CD73 Antibody [AD2]	CD73, also known as ecto-5'-nucleotidase, is a 70 kDa, glycosyl phosphatidylinositol (GPI)-anchored glycoprotein. CD73 is expressed on subsets of T and B lymphocytes, follicular dendritic cells, epithelial cells, endothelial cells and mesenchymal stem cells. Its expression on lymphocytes increases during T and B cell development. CD73 has enzymatic activity and catalyzes the dephosphorylation of adenosine monophosphate (AMP), converting it to adenosine. It has been suggested that CD73 can mediate costimulatory signals in T cell activation and adhesion of lymphocytes to endothelium.
H1996	FITC Human CD79b/Igβ Antibody [CB3-1]
H0541	FITC Human CD8 Antibody [SK1]	CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
H2416	FITC Human CD81 Antibody [JS-81]	CD81 is an ~26 kDa transmembrane protein that belongs to the tetraspanin (TM4SF) family. It is involved in cell growth and signal transduction. CD81 has a very broad cellular distribution, being expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin. In hematopoietic cells, the CD81 antigen is expressed on B and T lymphocytes, NK cells, thymocytes, eosinophils, germinal center follicular dendritic cells, and to a variable extent on monocytes. The CD81 antigen is not expressed on neutrophils, platelets, or erythrocytes. CD81-specific antibodies have been shown to have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. They are also reported to induce homotyp
H1471	FITC Human CD83 Antibody [HB15e]	CD83 is a 45 kDa type I transmembrane glycoprotein that belongs to the immunoglobulin (Ig) superfamily. It is composed of a single V-type Ig extracellular domain and a C-terminal cytoplasmic tail. CD83 is primarily expressed on the surface of follicular dendritic cells, circulating dendritic cells, interdigitating dendritic cells in lymphoid tissues, in vitro-generated dendritic cells, and thymic dendritic cells. However, its expression is not limited to dendritic cells; it is also found on some germinal center B cells and certain lymphoblastoid cell lines. While the exact function of CD83 is not fully understood, it is believed to play a role in cell-cell interactions during antigen presentation.
H4021	FITC Human CD9 Antibody [HI9a]
H0301	FITC Human CD90 Antibody [P15F7]	CD90, also known as Thy-1, is a 25-35 kDa glycophosphatidylinositol-anchored membrane glycoprotein of the Ig superfamily. It is expressed on 1-4% of human fetal liver cells, cord blood cells, and bone marrow cells. CD90 is present on a subset of immature CD34+ cells and a distinct subset of mature CD34- cells that are CD3+CD4+. The CD90+CD34+ population is highly enriched for cells capable of long-term culture. The anti-CD90 antibody is useful for enriching high proliferative potential colony-forming cells (HIPP-CFC), which are primitive progenitor cells.
H1816	FITC Human CD94 Antibody [HP-3D9]
H2041	FITC Human CD99 Antibody [3B2/TA8]
H1696	FITC Human Galectin-9 Antibody [9M1-3]
H2071	FITC Human Granzyme A Antibody [CB9]	Granzyme A is a 28 kD disulfide-linked homodimeric protein and the most abundant of the proteases occurring in CTL granules. It is homologous to other serine esterases, including other granyzmes, mast cell proteases, and neutrophil cathepsins. Granzyme B is thought to be a rapidly-acting apoptotic enzyme, while Granzyme A is slow acting.
H3091	FITC Human Granzyme K Antibody [GM26E7]
H1786	FITC Human HLA-A2 Antibody [BB7.2]	HLA-A2 is a class I molecule of the major histocompatibility complex (MHC) and part of the highly polymorphic group of cell-surface proteins encoded by the MHC gene locus. It plays a crucial role in the immune response by binding and presenting small antigenic protein fragments to antigen-specific receptors on T cells (TCR). Class I MHC molecules, like HLA-A2, bind peptides derived from intracellular antigens, such as viral and some bacterial antigens, which are recognized by CD8+ T cells. The TCRs recognize these processed peptides bound to the MHC, as well as regions of the MHC molecule itself, while CD4 and CD8 accessory molecules enhance the interaction by binding non-polymorphic regions of the MHC.
H0466	FITC Human HLA-DR Antibody [G46-6]	HLA-DR, a major histocompatibility complex (MHC) class II antigen, is encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells including B cells, dendritic cells, monocytes, macrophages, Langerhans cells, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.
H2611	FITC Human HLA-DR DP DQ Antibody [Tu39]
H3676	FITC Human Ig light chain lambda Antibody [MHL-38]
H3661	FITC Human Ig light chain κ Antibody [MHK-49]
H3691	FITC Human IgD Antibody [IA6-2]	IgD is a member of the immunoglobulin superfamily that exists in type 1-membrane (mIgD) and soluble glycoprotein forms. mIgD is expressed on mature naïve B cells (along with membrane IgM) and serves as a B-cell receptor for antigen (BCR). In response to antigen binding, the mIgD BCR, in association with other signaling molecules including CD79a and CD79b, can transduce activating or tolerizing signals intracellularly into B lymphocytes.
H3706	FITC Human IgG Antibody [G18-145]	IgG plays a critical role in the humoral immune response, helping to control infections. It is produced by plasma B-cells and is found in extracellular fluids such as blood, lymph, peritoneal, and cerebrospinal fluids. IgG molecules are monomers consisting of two identical heavy chains and two identical light chains, forming a Y-shaped structure with two antigen-binding sites. IgG facilitates pathogen neutralization, activates the complement system, promotes phagocytosis, and mediates antibody-dependent cellular cytotoxicity. It is also the main antibody involved in long-term immunity and can cross the placenta to provide passive immunity to the fetus. There are four IgG subclasses in humans, mice, and rats-IgG1, IgG2, IgG3, and IgG4-each w
H2266	FITC Human IgG Fc Antibody [M1310G05]	IgG Fc is a homodimer that is composed of the constant region of the two heavy chains that form the IgG molecule. The Fc fragment mediates opsonization, antibody dependent cellular cytotoxicity (ADCC), and complement activation through binding to Fc receptors such as CD16, CD32, CD64, and the complement factor C1.
H1006	FITC Human IgM Antibody [MHM-88]	IgM is the first immunoglobulin made by B cells in the immune response. Surface IgM is expressed on immature and mature B cells, while IgM heavy (μ) chain is expressed intracellularly in pre-B cells.
H1216	FITC Human IL-2 Antibody [MQ1-17H12]	Interleukin-2 (IL-2) is a key cytokine involved in immune response and tolerance. It is produced by activated T cells and plays a crucial role in the activation, growth, proliferation, and differentiation of various immune cells, including T and B lymphocytes, LAK cells, NK cells, and monocytes/macrophages. IL-2 exerts its effects through binding to IL-2 receptor complexes, which include the intermediate-affinity IL-2R (comprising IL-2Rβ and γc) and the high-affinity IL-2R (which also includes IL-2Rα, along with IL-2Rβ and γc). IL-2 is essential for the proper functioning of the immune system, particularly in promoting T cell expansion and immune responses.
H0421	FITC Human IL-4 Antibody [MP4-25D2]
H2626	FITC Human NKB1 Antibody [DX9]
H2851	FITC Human P-glycoprotein/CD243 Antibody [17F9]
H2476	FITC Human Siglec-8 Antibody [7C9]
H0961	FITC Human TCR gammadelta Antibody [B1]	The γ/δ TCR is a heterodimeric glycoprotein that is noncovalently associated with the CD3 antigen. The γ and δ TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. The γ chain forms either disulfide-linked or non–disulfide-linked heterodimers with the δ-subunit.
H2491	FITC Human TCR Vgamma9 Antibody [B3]	The Vγ9 TCR is a variant of the TCR γ chain expressed on a subset of γ/δ T cells. Vγ9Vδ2 T lymphocytes, a major γ/δ T cell subset in humans, recognize phosphoantigens, certain tumor cells, and cells treated with aminobisphosphonates. This cell population displays cytolytic activity against various tumor cells. The γ/δ TCR is a heterodimeric TCR complex composed of covalently bound γ and δ chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3δ, γ, ε, and ζ chains. The B3 antibody reacts specifically with human TCR Vγ9. Human TCR Vγ9 is also known as TCR Vγ2.
H3766	FITC Human TCR Vα24-Jα18 Antibody [6B11]
H1846	FITC Human TCR Vα7.2 Antibody [3C10]	The antibody recognizes the Vα7.2 T cell antigen receptor (TCR) α-chain segment which, joined with the Jα33 segment, constitutes an invariant TCR that is a characteristic of the mucosalassociated invariant T cells (MAIT cells). MAIT cells are restricted by a nonpolymorphic class Ib major histocompatibility complex (MHC) molecule, MHC-related molecule 1 (MR1). MAIT cells are present in human blood (1-8% of T cells), mesenteric lymph nodes, liver, and intestinal mucosa. MAIT cells play a role in detecting and fighting off microbial infections
H1486	FITC Human TCR α/β Antibody [IP26]	TCR α/β is a monomorphic determinant of the α/β T-cell receptor, which is expressed on over 95% of normal peripheral blood CD3+ T cells. The α/β T-cell receptor (TCR) plays a crucial role in recognizing peptides bound to MHC molecules, leading to T-cell activation.
G1591	FITC Human/Mouse Integrin β7 Antibody [FIB504]	Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via i
H0121	FITC IFN-gamma Antibody [4S.B3]
G0946	FITC IgM Antibody [II/41]	Mouse IgM is an immunoglobulin M antibody that is produced by B cells in response to an antigen. It is the first antibody produced during an immune response and is the largest immunoglobulin in the serum. Mouse IgM is composed of five heavy chains and five light chains, and it is involved in complement activation and agglutination of antigens. It plays a crucial role in the innate immune response and is important for neutralizing pathogens before the adaptive immune response is fully activated. Mouse IgM is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry.
G0181	FITC IL-17A Antibody [G2J2]
G1921	FITC IL-6 Antibody [MQ2-13A5]
G2536	FITC IRF4 Antibody [3E4]
G3946	FITC Junctional Adhesion Molecule 1/JAM-A Antibody [C23D13]
G0316	FITC Ki-67 Antibody [SolA15]	Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic t
G2656	FITC LAMP2 Antibody [H4B4]
G0361	FITC Ly-6A/E/Sca-1 Antibody [D7]	Stem Cell Antigen-1 (Sca-1) is a member of the lymphocyte antigen 6 (Ly-6) family. It is expressed on multipotent hematopoietic stem cells (HSC) and is used as a marker of HSC in mice. Sca-1 is used in combination with lineage depletion antibodies to identify murine HSC. Sca-1 can be found in fetal liver, adult bone marrow, and adult peripheral blood and spleen. Sca-1 may be involved in the regulation of B and T cell activation.
G3466	FITC Ly-6B.2 Alloantigen Antibody [7/4]	Rat anti Mouse Ly-6B.2 monoclonal antibody, recognizes the Ly-6B.2 antigen. Ly-6B.2 is a ~25-30 kDa GPI-anchored, heavily glycosylated protein expressed on neutrophils, inflammatory monocytes and some activated macrophages. High levels of expression are seen in bone marrow, spleen, lung and lymph nodes. N-glycanase treatment of thioglycollate elicited peritoneal neutrophil lysates lowers the apparent molecular weight of Ly-6B.2 to ~15 kDa. In common with other Ly-6 antigens Ly-6B.2 demonstrates a polymorphic expression on inbred mouse strains. Rat anti mouse Ly-6B.2, recognizes the Ly-6B.2 antigen in 129J; AKR; C57BL/6; C57BL/10; C58; DBA/2; NZB; NZW; SJL; MFI; Swiss (PO) Strains whilst A2G; A/Sn; ASW; BALB/c; C3H/HEH: CBA.T6T6 are negative
G2521	FITC MHC Class I/H-2Db Antibody [28-14-8]
G0436	FITC Mouse CD107a Antibody [1D4B]	CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1), is a type I transmembrane glycoprotein that serves as a key marker of lysosomes. It is composed of a 40 kDa core protein that is heavily glycosylated, resulting in a mature glycoprotein ranging from 110 to 140 kDa. CD107a is predominantly expressed in epithelial cells and macrophages across various organs. Upon cellular activation, it translocates to the cell surface of lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Surface expression of CD107a is involved in intercellular and extracellular matrix adhesion and is widely used as a functional marker of cytotoxic activity in NK cells and CD8+ T cells, as well as in identifying som
G2671	FITC Mouse CD107b Antibody [M3/84]
G0976	FITC Mouse CD146 Antibody [ME-9F1]	CD146, also known as melanoma cell adhesion molecule (MCAM or Mel-CAM), MUC18, S-Endo1, and A32 antigen, is an integral membrane glycoprotein that belongs to the Ig superfamily. CD146 is strongly expressed by murine vascular endothelial cells. It is expressed on about 30% of neutrophils and 60% of NK cells. Unlike in humans, CD146 is undetectable on monocytes, dendritic cells, T cells, NKT cells, B cells, or smooth muscle cells in mouse. It has been reported that an increase in CD146 expression is associated with NK cell maturation. Combined with using CD27 and CD11b staining, CD146 may be an alternative marker to detect final stages of NK cell maturation and define NK cell subsets. CD146+ NK cells were found to be less cytotoxic and to pro
G1531	FITC Mouse CD16.2/FcgammaRIV Antibody [9E9]
G4231	FITC Mouse CD16/CD32 Antibody [2.4G2]	CD16 and CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. These receptors bind to the Fc portion of antibody-antigen complexes and play a role in adaptive immune responses.
G3001	FITC Mouse CD172a/SIRPα Antibody [P84]
G1156	FITC Mouse CD18 Antibody [M18/2]
G1081	FITC Mouse CD185 Antibody [2G8]	The Rat Anti-Mouse CD185 (CXCR5) monoclonal antibody specifically binds to the mouse C-X-C Chemokine Receptor type 5, CXCR5. CXCR5 is also known as CD185, BLR1, NLR and MDR15. CXCR5 is a seven-transmembrane, G-protein-coupled receptor that is specific for the CXC chemokine, CXCL13/BLC/BCA-1. The expression of CXCR5 has been detected in spleen, lymph nodes, tonsils, brain, bone marrow, T cells, B cells, cerebrum, cerebellum, hippcampus and pituitary. In mouse spleen, CXCR5 was strictly expressed by mature B cells and a small subset of T lymphocytes. CXCR5 plays a role in directing the migration of B and T cells to B cell follicles with the spleen and certain other lymphoid tissues. The immunogen used to generate 2G8 hybridoma was a recombina
G4381	FITC Mouse CD19 Antibody [1D3]	CD19, a B lymphocyte-lineage differentiation antigen and a 95-kDa transmembrane glycoprotein, is a member of the immunoglobulin superfamily and is expressed throughout B-lymphocyte development from the pro-B cell stage through mature B cells. Terminally differentiated plasma cells do not express CD19. On mature B cells, CD19 associates with CD21 (CR-2) and CD81 (TAPA-1), forming a multimolecular complex that synergizes with surface immunoglobulin to promote cellular activation. Studies in CD19-deficient mice suggest that the level of CD19 expression influences the generation and maturation of B cells in both bone marrow and peripheral tissues. B-1 lineage B cells, also called CD5+ B cells, are drastically reduced or absent in CD19-deficient
G4066	FITC Mouse CD206/MMR Antibody [C068C2]	CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and ada
G0811	FITC Mouse CD21/CD35 Antibody [7G6]	This antibody recognizes an epitope shared by 145-150-kDa and 190-kDa complement receptor proteins, originally designated CR2 (CD21) and CR1 (CD35), respectively. In the mouse, CD21 and CD35 are expressed on the majority of peripheral B lymphocytes, on the majority of resident peritoneal macrophages and mast cells, on peripheral blood granulocytes after treatment with N-formyl-Met-Leu-Phe, and on follicular dendritic cells, but not on thymocytes, T cells, erythrocytes, or platelets. CD21 is a ligand-binding component of the CD19/CD21/CD81 signal-transduction complex associated with the antigen receptor on B lymphocytes. CD21/CD35 also co-localizes with CD19 on the surface of peritoneal mast cells. Cr2null mice display impaired inflammatory
G2851	FITC Mouse CD22 Antibody [Cy34.1]
G4201	FITC Mouse CD25/IL-2Rα Antibody [PC61.5]	Interleukin-2 receptor alpha (IL-2Rα), also known as CD25, Ly-43, p55, or Tac, is the 55 kDa ligand-binding subunit of the interleukin-2 receptor. IL-2Rα is expressed on activated mature T and B lymphocytes, thymocyte subsets, pre-B cells, and T regulatory cells. IL-2Rα plays roles in lymphocyte differentiation, activation, and proliferation. Alone, IL-2Rα binds IL-2 with relatively low affinity; however, when IL-2Rα associates with IL-2Rβ (CD122) and the common gamma chain (CD132), the complex binds IL-2 with high affinity.
G2866	FITC Mouse CD26 Antibody [H194-112]
G1861	FITC Mouse CD268/BAFF-R Antibody [7H22-E16]	BAFF (B cell-activating factor belonging to the TNF family) receptor (BAFF-R) is one of the three receptors that bind to BAFF. It is a type III transmembrane TNF receptor family member. BAFF-R is expressed at high levels in resting B cells and at lower levels in activated B cells, a small subset of activated/memory CD4+ T cells. It is a major mediator of BAFF dependent co-stimulatory response in peripheral B and T cells. It was reported that the mice expressing defective BAFF-R have disrupted B cell maturation. BAFF receptor appears to be particularly important for the regulation of normal B cell survival and maturation, as well as in the pathophysiology of aggressive B-cell malignancies and autoimmune diseases.
G4636	FITC Mouse CD3 Antibody [17A2]	CD3ε is one of five polypeptide chains that combine to form the TCR complex. CD3ε is expressed on T lymphocytes, NK-T cels, and to varying degrees on developing thymocytes. CD3 plays roles in TCR signaling, T lymphocyte activation, and antigen recognition.
G1411	FITC Mouse CD317 Antibody [927]
G1246	FITC Mouse CD357/GITR Antibody [DTA-1]	CD357, also known as GITR (Glucocorticoid-induced Tumor Necrosis Factor Receptor family-Related), is a 66-70 kDa homodimer glycoprotein that belongs to the TNF receptor superfamily. It is also referred to as TNFRSF18. GITR expression was first identified in T lymphocytes treated with dexamethasone, a glucocorticoid. In normal naive mice, GITR is expressed at moderate levels on CD25-positive/CD4-positive/CD8a-negative thymocytes and on CD25-positive/CD4-positive/CD45RB-low splenocytes. It is also expressed at low levels on splenic CD25-negative/CD4-positive/CD45RB-low T lymphocytes, B lymphocytes, macrophages, and dendritic cells. GITR expression is upregulated upon activation of T and B lymphocytes. As a costimulatory receptor, GITR plays a
G0841	FITC Mouse CD38 Antibody [90]	CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscle, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.
G4156	FITC Mouse CD3epsilon Antibody [145-2C11]	CD3epsilon is a 20 kDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. It is one of five polypeptide chains that combine to form the T cell receptor (TCR) complex. CD3ε is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. CD3 plays critical roles in TCR signaling, T lymphocyte activation, and antigen recognition.
G4141	FITC Mouse CD4 Antibody [GK1.5]	The CD4 antigen is a 55 kDa cell surface type I membrane glycoprotein belonging to the immunoglobulin superfamily. CD4 acts as a co-receptor which, in cooperation with the T cell receptor (TCR), interacts with class II MHC molecules displayed by antigen-presenting cells (APC). CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells, and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.
G0511	FITC Mouse CD40 Antibody [1C10]
G0856	FITC Mouse CD41 Antibody [MWReg30]	CD41 is a transmembrane glycoprotein that is encoded by Itga2b. CD41 associates with Integrin β3 chain (gpIIIa or CD61) to form the gpIIb/IIIa (CD41/CD61) complex. CD41/CD61 is expressed on platelets, megakaryocytes, and early hematopoietic progenitors. The integrin complex binds to fibrinogen, fibronectin, vitronectin, von Willebrand factor, and thrombospondin. It is important for platelet adhesion and aggregation, and it may play a role in osteolytic tumor metastasis.
G1036	FITC Mouse CD43 Activation-Associated Glycoform Antibody [1B11]	CD43, also known as Ly-48, Leukosialin, Sialophorin, Leukocyte Sialoglycoprotein, and gp115, is a large single chain of type I transmembrane glycoprotein with abundant O-glycosylation and sialylation sites. Due to variable glycosylation and sialylation, two isoforms of CD43 have been identified. The 115 kD glycoform of CD43 is expressed on most hematopietic cells including T lymphocytes, NK cells, monocytes, granulocytes, platelets, and CD5+ B cells. It is not present on resting B cells and erythrocytes. While the 130 kD glycoform is thought to be activation-associated form primarily expressed on myeloid cells, pre-B cells, and activated T cells. It has been reported that CD43 binds to CD54 and Siglec-1. CD43 plays dual roles in cell adhesi
G1651	FITC Mouse CD45RB Antibody [C363.16A]
G0526	FITC Mouse CD49b Antibody [DX5]	CD49b is a 150 kDa transmembrane glycoprotein that non-covalently associates with CD29 (integrin β1) to form the integrin α2β1 complex known as VLA-2. The rat anti-mouse CD49b antibody has been reported to identify the majority of NK cells and a small T-cell subpopulation in most mouse strains (e.g., A/J, AKR, BALB/c, C3H/HeJ, C57BL/6, C57BL/10, C57BR, C58, CBA/Ca, DBA/1, DBA/2, SJL, SWR, 129/J, but not NOD). The DX5 antibody also recognizes platelets that express high levels of CD49b.
G0541	FITC Mouse CD49b Antibody [HMα2]	CD49b is a 150 kD glycoprotein, also known as α2 integrin, VLA-2 α chain, Integrin α2 chain, and HMα2. It is a member of the integrin family, expressed on NK cells, a subset of splenic CD4+ T cells, NK-T cells, intestinal intraepithelial and lamina propria lymphocytes, epithelial cells, and platelets. By associating with CD29 (integrin β1 subunit), CD49b forms the VLA-2 (integrin α2β1 ) complex. It plays a critical role in both adhesion and lymphocyte activation. The primary ligands for CD49b are collagen, laminin, and fibronectin.
G1111	FITC Mouse CD54 Antibody [YN1/1.7.4]	CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. Antibodies against CD54 can block its interaction with LFA-1 and Mac-1, thereby inhibiting cell-cell adhesion, impairing antigen prese
G2461	FITC Mouse CD55 Antibody [RIKO-3]
G2941	FITC Mouse CD64 Antibody [X54-5/7.1]	CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcRI. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and mast cells. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).
G1741	FITC Mouse CD79b/Igβ Antibody [HM79-12]
G1321	FITC Mouse CD83 Antibody [Michel-19]
G4411	FITC Mouse CD86 Antibody [GL1]	CD86, along with CD80, is a member of the B7 family of costimulatory molecules and plays a crucial role in T cell activation and immune response regulation. CD86 is expressed at low levels on B cells, macrophages, and dendritic cells, and its expression is upregulated on B cells through various stimuli, including the BCR complex, CD40, and certain cytokine receptors. As a type I membrane protein and member of the immunoglobulin superfamily, CD86 serves as a ligand for the T cell surface proteins CD28 and CTLA-4 (CD152). The interaction between CD86 and CD28 provides a costimulatory signal essential for T cell activation during antigen presentation, while binding with CTLA-4 negatively regulates T cell activation, diminishing the immune resp
G4456	FITC Mouse CD8a Antibody [2.43]	The CD8 antigen is a transmembrane glycoprotein that acts as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to class I MHC molecules displayed by antigen presenting cells (APC). CD8 is primarily expressed on the surface of cytotoxic T cells, but can also be found on thymocytes, natural killer cells, and some dendritic cell subsets. CD8 most commonly exists as a heterodimer composed of one CD8α and one CD8β chain however, it can also exist as a homodimer composed of two CD8α chains. Both the CD8α and CD8β chains share significant homology to immunoglobulin variable light chains. The molecular weight of each CD8 chain is approximately 34 kDa.
G4846	FITC Mouse CD8β Antibody [53-5.8]	The CD8 antigen is a transmembrane glycoprotein that acts as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to class I MHC molecules displayed by antigen presenting cells (APC). CD8 is primarily expressed on the surface of cytotoxic T cells, but can also be found on thymocytes, natural killer cells, and some dendritic cell subsets. CD8 most commonly exists as a heterodimer composed of one CD8α and one CD8β chain however, it can also exist as a homodimer composed of two CD8α chains. Both the CD8α and CD8β chains share significant homology to immunoglobulin variable light chains. The molecular weight of each CD8 chain is approximately 34 kDa.
G1051	FITC Mouse CX3CR1 Antibody [SA011F11]	CX3CR1 is a 40 kD, G-protein coupled receptor, with seven transmembrane regions. CX3CR1 is expressed by resident and alternatively activated macrophages (M2), a subset of monocytes, dendritic cells (DCs), NK cells, a subset of memory T cells, and mast cells. CX3CR1 is involved in cell recruitment during inflammation and participates in cell adhesion and extravasation from blood vessels. Its ligand is CX3CL1, also known as fractalkine or neurotactin. CX3CR1 is also a coreceptor for HIV1 and variations in this gene leads to increased susceptibility to HIV. In the brain, it is expressed by glial cells, which interact with CX3CL1 expressed by neurons.
G1801	FITC Mouse H-2Kb Antibody [AF6-88.5]	H-2Kb is a mouse MHC class I alloantigen expressed on all nucleated cells of mice with the H-2^b haplotype. It plays a key role in presenting endogenous peptides to CD8+ T cells, enabling immune surveillance and cytotoxic T cell responses.
G1501	FITC Mouse I-A[b] Antibody [AF6-120.1]	I-A[b] is a major histocompatibility complex (MHC) class II molecule found on antigen-presenting cells such as B cells, dendritic cells, and macrophages. It presents peptides derived from extracellular proteins to CD4+ T helper cells, playing a critical role in initiating and regulating adaptive immune responses
G4171	FITC Mouse IFNγ Antibody [R4-6A2]
G3121	FITC Mouse Ig, lambda1, lambda2 & lambda3 Light Chain Antibody [R26-46]
G3136	FITC Mouse IgD Antibody [11-26c.2a]	IgD is a crucial marker for B cell differentiation, appearing when B cells leave the bone marrow and mature in peripheral lymphoid tissues. It is co-expressed with IgM on mature naïve B cells and acts as an antigen receptor. IgD plays an essential role in regulating B cell activation, survival, and tolerance. The expression of IgD helps distinguish mature B cells from immature ones, contributing to the shaping of the naïve B cell compartment and maintaining immune homeostasis.
G3151	FITC Mouse IgG1 Antibody [A85-1]	IgG1 is a subclass of immunoglobulin G, consisting of two identical gamma heavy chains and two identical light chains, forming a Y-shaped glycoprotein. Produced by plasma B cells, IgG1 plays a key role in immune defense by recognizing and neutralizing pathogens. Its variable regions bind specific antigens, while the constant region mediates effector functions such as complement activation and binding to Fc receptors. In mice, IgG1 is the predominant IgG subclass produced in response to protein antigens and is commonly found on the surface of B cells and in the serum.
G4186	FITC Mouse IgG1 isotype control Antibody [MOPC-21]	Mouse IgG1 isotype control is a mouse myeloma protein. It was selected as an isotype control following screening for low background on a variety of mouse and human tissues.
G3166	FITC Mouse IgG2a Antibody [R19-15]	The antibody recognizes an epitope in the CH3 domain of mouse IgG2a, with strong reactivity to the Igh-I[a] allotype and weaker reactivity to Igh-I[b]. It does not react with other Ig isotypes. Molecular genetic analyses suggest that the Igh-I[b] allele, which encodes IgG2a[b], is derived from a locus found in several wild mouse subspecies, but not domestic mice, which encodes the IgG2c isotype.
G4876	FITC Mouse IgG2a isotype control Antibody [C1.18.4]	The Mouse IgG2a isotype control antibody is ideal for use as a non-reactive isotype-matched control for mouse IgG2a antibodies in most in vivo and in vitro applications.
G0871	FITC Mouse IgG2a kappa Isotype Control Antibody [G155-178]	The Mouse IgG2a kappa Isotype Control has an unknown specificity. Trinitrophenol (TNP), the immunogen, is a hapten not expressed on human, mouse, rat or non-human primate cells. In the absence of specific binding, this antibody may bind non-specifically to immunoglobulin Fc receptors.
G3181	FITC Mouse IgG2b Antibody [RMG2b-1]
G0781	FITC Mouse IL-10 Antibody [JES5-16E3]	IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. D
G4276	FITC Mouse IL-6 Antibody [MP5-20F3]
G4321	FITC Mouse LAG-3 Antibody [C9B7W]
G1636	FITC Mouse LAP/TGF-β1 Antibody [TW7-16B4]
G4306	FITC Mouse LFA-1α/CD11a Antibody [M17/4]	LFA-1α (lymphocyte function-associated antigen 1 alpha), also known as integrin alpha L chain and CD11a, pairs with CD18 to form LFA-1, a 180 kDa integrin glycoprotein belonging to the integrin family. LFA-1 is expressed on the surface of all leukocytes, including lymphocytes, monocytes, macrophages, and granulocytes. It plays a central role in leukocyte intercellular adhesion through interactions with its ligands ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50), and also contributes to lymphocyte costimulatory signaling.
G4426	FITC Mouse Ly6G Antibody [1A8]	Lymphocyte antigen 6 complex, locus G (Ly-6G), is a 21–25 kDa GPI-anchored protein expressed primarily on peripheral granulocytes and highly specific for neutrophils. Ly-6G serves as a robust marker for neutrophil identification and depletion in mice. Ly-6G modulates neutrophil migration and recruitment to sites of inflammation via interaction with β2 integrins. Its downregulation is associated with age-related functional decline in neutrophils.
G4336	FITC Mouse Ly6G/Ly6C Antibody [RB6-8C5]	Lymphocyte antigen 6 complex, locus G (Ly-6G), also known as Ly6C, Gr-1, is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein with a molecular weight of approximately 21–25 kDa. It is commonly used as a specific marker for peripheral granulocytes, particularly neutrophils, in mice. Ly-6G is predominantly expressed on myeloid-derived cells in the bone marrow and exhibits high specificity for neutrophils, though it can also be detected on some monocytes and granulocyte subsets. This specificity makes Ly-6G a robust marker for identifying and studying neutrophil populations and their roles in immune responses in murine models.
G4246	FITC Mouse NK1.1 Antibody [PK136]	NK1.1, also known as CD161b/CD161c, KLRB1, NKR-P1A, and Ly-55, is a type II integral membrane glycoprotein with a C-type lectin domain and is encoded by the Klrb1c/NKR-P1C gene. NK1.1 plays roles in NK cell activation and differentiation, IFN-γ production, cytotoxic granule release, and is thought to be involved in the generation of Th2 cells. NK1.1 is predominantly expressed as a disulfide-linked homodimer on NK cells; however, it is also expressed on NK-T cells, a rare population of T lymphocytes. NK1.1 is only expressed by C57BL/6, FVB/N, and NZB strains of mice and not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129 strains.
G4801	FITC Mouse OX40 Antibody [OX-86]
G1666	FITC Mouse TCR Vα2 Antibody [B20.1]	TCR Vα2 is a distinct T-cell receptor (TCR) subfamily found in mice with the a, b, and c haplotypes. The TCR α chain complexes with the TCR β chain in 95% of T cells, forming the T cell receptor (α/β TCR), while the remaining 5% of T cells express gamma (γ) and delta (δ) chains (γ/δ TCR). TCR Vα2 represents a specific variant of the TCR α chain that plays a role in antigen recognition and is useful in the study of T-cell function and immune responses in mice with these specific haplotypes.
G4351	FITC Mouse Ter-119 Antibody [TER-119]	TER-119 is a lineage marker for erythroid cells from early proerythroblast to mature erythrocyte stages in adult blood, spleen, and bone marrow. It is also present in yolk sac, and fetal and newborn liver. The TER-119 antigen is not expressed by cells of earlier erythroid development at BFU-e (blast-forming unit erythroid) stage or CFU-e (colony-forming unit erythroid) stage.
G4891	FITC mouse TIGIT Antibody [1G9]	TIGIT is a 26 kDa, type I transmembrane protein and a member of the poliovirus receptor (PVR) family. TIGIT has been found to be expressed on follicular T helper cells in mice while in humans it’s expressed by many T cell subsets including activated T cells, follicular T helper cells, memory T cells, and regulatory T cells as well as on NK cells. TIGIT can interact with certain members of the PVR and PVR-like families, including PVR, PVRL2, PVRL3, CD155, and CD112. TIGIT is thought to negatively regulate NK and T cell activation. Binding of TIGIT on T cells by dendritic cells results in their differentiation into a tolerogenic phenotype, with increased secretion of IL-10 and diminished production of IL-12. TIGIT knock-out mice are more susc
G4666	FITC mouse/human CD11b Antibody [M1/70]
G2026	FITC Mouse/rat CD81 Antibody [Eat-2]	CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1. CD81 is expressed on T and B cells, NK cells, dendritic cells, thymocytes, endothelial cells, and fibroblasts. CD81 induces B cell adhesion via the VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.
G3256	FITC Mouse/rat XCR1 Antibody [ZET]
H4216	FITC Neuron-specific beta-III Tubulin Antibody [TuJ-1]	β-III Tubulin, also known as tubulin β-4, is regarded as a neuron-specific marker. The expression of β-III Tubulin has been suggested to be one of the earliest markers to signal commitment in primitive neuroepithelium.
G3841	FITC Phospho-Histone H2A.X (Ser139) Antibody [E5F13]
G3886	FITC Phospho-Zap-70 (Tyr319)/Syk (Tyr352) Antibody [L15L21]
G1291	FITC Podoplanin Antibody [L7B2]	Podoplanin (PDPN, T1A, gp38, Aggrus) is a mucin type-1 glycoprotein with a 40-43 kDa molecular weight. Podoplanin is expressed in many tumors and normal cells, especially lymphatic epithelial cells and follicular DCs. Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. Podoplanin appears to serve as a ligand for CLEC-2 and expression is positively correlated with tumors expressing greater invasive and metastatic potential. Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue. Further, it has also been determined that
G4291	FITC Rat IgG2a isotype control Antibody [2A3]	Rat IgG2a isotype control antibodies are immunoglobulins that lack specificity for mammalian antigens. They serve as essential negative controls in immunological assays, helping to distinguish specific antibody binding from background or non-specific interactions in both in vivo and in vitro applications.
G0631	FITC Rat IgG2a kappa Isotype Control Antibody [eBR2a]	Rat IgG2a is an immunoglobulin subclass that is commonly used in research and diagnostic applications. It is produced by the rat immune system and is known for its ability to activate complement and mediate antibody-dependent cell-mediated cytotoxicity (ADCC). Rat IgG2a has a molecular weight of approximately 160 kDa and is composed of two heavy chains and two light chains. It is often used as a control or reference antibody in experiments involving rat models, and is also commonly used in flow cytometry and immunohistochemistry applications.
G3661	FITC Rat IgG2a λ Isotype Control Antibody [G013C12]
G4486	FITC Rat IgG2b Isotype Antibody [LTF-2]	The Rat IgG2b isotype antibody reacts with keyhole limpet hemocyanin (KLH). Because KLH is not expressed by mammals this antibody is ideal for use as an isotype-matched control for rat IgG2b antibodies in most in vivo and in vitro applications.
G0886	FITC Rat IgG2b kappa Isotype Control Antibody [eB149/10H5]	Rat IgG2b is a protein-coding gene that encodes for the immunoglobulin G2b (IgG2b) subclass of rat antibodies. IgG2b is a major subclass of rat immunoglobulins that plays a crucial role in the immune response by neutralizing pathogens and promoting opsonization. Rat IgG2b is commonly used in research applications, such as in immunohistochemistry, flow cytometry, and Western blotting.
G0616	FITC T-bet Antibody [B2D24]	T-bet, also known as TBX21, is a T-cell specific transcription factor containing a single T-box DNA-binding domain. It controls the expression of the TH1 cytokine, interferon-gamma. Both Th1 and Th17 cells are crucial in immune regulation and autoimmune disease development. T-bet initiates Th1 lineage development from naive Th precursor cells and directs T cell differentiation to Th1 versus Th17. T-bet is cooperating with Stat4 (signal tranducer and activator of transcription 4) in programming chromatin architecture for Th1 gene expression. Genetic variations in T-bet are associated with susceptibility to aspirin-induced asthma and nasal polyps.
G0916	FITC TCR gammadelta Antibody [J18P6]	TCR gamma/delta (T-cell receptor gamma/delta) are specialized T-cells in the immune system. The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflamm
H3271	FITC TCR Vδ1 Antibody [TS8.2]
G0286	FITC TCR-β Antibody [H57-597]	The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system c
H1306	FITC TIGIT Antibody [MBSA43]
G3421	FITC TLR4/MD-2 Complex Antibody [MTS510]	MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.
H2341	FITC TLR9 Antibody [26C593.2]	Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. TLR9 forms a subfamily along with TLR7 and TLR8 that recognize viral RNA and CpG DNA sequences and are localized in intracellular acidic compartments such as the phagolysosome. Unlike other TLRs which act through adaptor molecules such as TOLLIP, TIRAP, TRIF, and MyD88 to activate various kinases and transcription factors to respond to potential infection, TLR9 is strictly dependent on MyD88.
H0346	FITC TNF-α Antibody [MAb11]	TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. It is mainly secreted by macrophages and binds to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. It exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions. Knockout studies in mice suggested the neuroprotective function of TNF alpha, and it has been observed to cause tumor necrosis when injected into tumor-bearing mice. Other functions of TNF-alpha include its role in the immune response to
G3916	FITC VISTA Antibody [G23H7]
G3856	FITC Zap-70 Antibody [A12A8]
E2695	FITC-Dextran (MW 10000)	FITC-Dextran(MW 10000) are polysaccharides comprised of varying lengths of branched glucose molecules and can be used to determine solute, ion and protein permeability of the blood-brain barrier (BBB) based on the size of the dextran used.
S2595	FK-3311	FK-3311 (COX-2 Inhibitor V) is a selective, cell-permeable and orally available inhibitor of cyclooxygenase-2 (COX-2) with antiinflammatory. FK-3311 has protective effects against hepatic warm ischemia-reperfusion injury by marked inhibition of TxA2.
S2799	FK866 (Daporinad)	Daporinad (FK866) effectively inhibits nicotinamide phosphoribosyltransferase (NMPRTase; Nampt) with IC50 of 0.09 nM in a cell-free assay. Daporinad (FK866, APO866) triggers autophagy. Phase 1/2.
S0535	FK962	FK962, a derivative of FK960 with putative anti-dementia properties, significantly enhances high K+-evoked somatostatin release from rat hippocampal slices at 1-1000 nM, also significantly reduces somatostatin-induced inhibition of Ca2+ channels at 1-100 nM in single rat hippocampal neurons.
F3489	FKBP12 Antibody [H17G5]
A5897	FKBP12 Rabbit Recombinant mAb	FKBP12 Rabbit Recombinant mAb detects endogenous levels of total Mutant FKBP12.
F1130	FKBP51 Antibody [B3H8]	FKBP5,FKBP51
F3799	FKBP52 Antibody [P6D1]
S1027	FL-411	FL-411 (BRD4-IN-1) is a potent and selective inhibitor of Bromodomain-containing protein 4 (BRD4) with IC50 of 0.43 μM for BRD4(1). FL-411 induces ATG5-dependent autophagy-associated cell death (ACD) by blocking BRD4-AMPK interaction.
E1713	FL118	FL118(10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin analog, is a potent and orally active inhibitor of Survivin. FL118 also selectively and independently inhibits three additional cancer-associated survival genes Mcl-1, XIAP, and cIAP2 in a p53 status-independent manner. FL118 displays potent antitumor activity and can be used in cancer research.
E8157	FLAG peptide	DYKDDDDK peptide is an eight-amino-acid (Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys) epitope tag used for protein purification and detection. It enables antibody-mediated purification via affinity chromatography, Western blot, and immunoprecipitation. The hydrophilic and immunogenic tag can be fused to either the N- or C-terminus of proteins.
E7573	Flagelin 22	Flagelin 22 (flg22; Flagellin 22) is a synthetic 22-amino-acid peptide derived from bacterial flagellin that serves as a potent elicitor of plant innate immunity. It specifically binds to the pattern recognition receptor FLAGELLIN SENSITIVE 2 (FLS2), triggering the formation of a receptor complex with the coreceptor BRI1-ASSOCIATED KINASE 1 (BAK1) and initiating FLS2 endocytosis. This receptor activation leads to a cascade of immune responses, most notably the rapid production of reactive oxygen species (ROS).
E7736	FlAsH-EDT2	FlAsH-EDT2 is a protein labeling reagent. FlAsH-EDT2 also is a membrane-permeant fluorogenic biarsenicals. FlAsH-EDT2 binds to CCXXCC motifs and non-specifically to endogenous cysteine-rich proteins. FlAsH-EDT2 can be useful only for labeling those recombinant proteins that express at a very high level.
E3094	Flatstem Milkvetch Seed Extract	Flatstem Milkvetch Seed Extract is obtained from the dried ripe seed of Flatstem Milkvetch, benefits the liver and the kidney, arrests seminal discharge, restrains urination and improves eyesight.
S3679	Flavanone	Flavanones (2,3-Dihydroflavone, 4-Flavanone, 2-Phenyl-4-chromanone, 2-Phenylchroman-4-one) show strong antioxidant and radical scavenging activity, and appear to be associated with a reduced risk of certain chronic diseases, the prevention of some cardiovascular disorders, and certain kinds of cancer. Flavanones also exhibit antiviral, antimicrobial, and anti-inflammatory activities, beneficial effects on capillary fragility, and an ability to inhibit human platelet aggregation, anti-ulcer, and anti-allergenic properties.
E0705	Flavin Adenine Dinucleotide Disodium	Flavin Adenine Dinucleotide Disodium is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.
S5600	Flavokawain A	Flavokawain A, extracted from kava, is an apoptotic inducers and anticarcinogenic agent. Flavokawain A can down-regulation of antiapoptotic proteins, such as XIAP, survivin, and Bcl-xL, thereby changing the balance between apoptotic and antiapoptotic molecules and then induce cell death in tumor cells.
S3967	Flavone	Flavone (2-Phenylchromone, 2-Phenyl-4-chromone, 2-Phenyl-4-benzopyron), a class of flavonoids, mainly found in spices and red or purple plant foods with antioxidant, anti-proliferative, anti-tumor, anti-microbial, estrogenic, acetyl cholinesterase, anti-inflammatory activities and are also used in cancer, cardiovascular disease, neurodegenerative disorders etc.
L7700	Flavonoid Compound Library	A unique collection of 264 flavonoid compounds used for high throughput screening(HTS) and high content screening(HCS).
S1230	Flavopiridol (Alvocidib)	Flavopiridol (Alvocidib) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4, CDK6, and CDK9 with IC50 values in the 20-100 nM range. It is more selective for CDK1, 2, 4, 6, 9 versus CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Flavopiridol induces autophagy and ER stress. Flavopiridol blocks HIV-1 replication. Phase 1/2.
S2679	Flavopiridol (Alvocidib) HCl	Flavopiridol (Alvocidib) HCl competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM in cell-free assays. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Flavopiridol HCl induces autophagy and ER stress. Flavopiridol HCl blocks HIV-1 replication. Phase 1/2.
S4027	Flavoxate HCl	Flavoxate (NSC-114649) is a muscarinic AChR antagonist with IC50 of 12.2 μM.
E3796	Flaxseed Extract	Flaxseed Extract is drawed from Linum usitatissimum, which can regulate the growth of MCF-7 cells and induce apoptosis.
F0730	FLCN Antibody [B7L9]
E0528	Flecainide	Flecainide is a common medication used to help restore and maintain sinus rhythm in patients with atrial fibrillation.
E4893	Flecainide hydrochloride	Flecainide hydrochloride, an antiarrhythmic drug, is a blocker of hydrophilic sodium channels with a pKa of 9.3. At pH 7.4. It also inhibits the ryanodine receptor (RyR2), reducing spontaneous calcium release from the sarcoplasmic reticulum.
S2469	Fleroxacin	Fleroxacin (Ro 23-6240,AM-833,Quinodis, Megalocin) is a new broad-spectrum fluoroquinolone.
E8290	Flezurafenib	Flezurafenib is an oral inhibitor of pan-RAF with potential antineoplastic activity.
S7399	FLI-06	FLI-06 is a novel inhibitor of Notch signaling with EC50 of 2.3 μM.
F2418	FLI1 Antibody [N12C20]
S3716	Flibanserin	Flibanserin (BIMT-17, BIMT-17-BS) is a nonhormonal, centrally acting molecule that acts as an agonist at postsynaptic 5-HT1A receptors and as an antagonist at 5-HT2A receptors.
F0682	FLIP Antibody [D8J7]	FLIP,FLIPS/L
S7259	FLLL32	FLLL32 is a potent JAK2/STAT3 inhibitor with IC50 of <5 μM. FLLL32 inhibits the induction of STAT3 phosphorylation by IFNα and IL-6 in breast cancer cells.
E4720	Flonoltinib	Flonoltinib (JAK2/FLT3-IN-1) is a potent and selective dual inhibitor of JAK2 and FLT3, with IC50 of of 0.8, 1.4, and 15 nM against JAK2, JAK2^V617F, and FLT3, respectively, in in vitro kinase assays. It also inhibits cell proliferation and induces G2/M cell cycle arrest and apoptosis in Hemophagocytic Lymphohistiocytosis (HLH) patients' CD8+T cells, CTLL2 cells, and RAW 264.7 cells.
S4249	Flopropione	Flopropione is a spasmolytic or antispasmodic agent, and acts as a 5-HT1A receptor antagonist.
S4201	Florfenicol	Florfenicol (SCH-25298,(-)-Florfenicol) is a fluorinated synthetic analog of thiamphenicol with broad-spectrum, primarily bacteriostatic activity.
E3787	Flos Inulae Extract	Flos Inulae Extract is drawed from Flos Inulae, which can be applied to antimutation, antityrosinase and anti-inflammation.
A4072	Flotetuzumab (Anti-CD3 & CD123)	Flotetuzumab is a bispecific DART antibody targeting CD123 on tumor cells and CD3ε on T-cells to stimulate immune cell-mediated tumor lysis. It is being developed for the treatment of hematological malignancies by enhancing T-cell responses against CD123-expressing tumors. M.W 58.91 kDa
F3788	Flotillin 1 Antibody [J14F12]	Flotillin 1,Flotillin-1
F0683	Flotillin-1 Antibody [B16D19]	Flotillin 1,Flotillin-1
A5227	Flotillin-2 Rabbit Recombinant mAb	Flotillin-2 Rabbit Recombinant mAb detects endogenous level of total Flotillin-2.
S1299	Floxuridine (FUDR)	Floxuridine (FUDR) is a prodrug that is rapidly catabolized to 5-fluorouracil in vivo. Floxuridine is used to treat various cancers, particularly metastases to the liver. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage and apoptosis. Floxuridine has antiviral effects against HSV and CMV.
E2387	FLT3-IN-2	FLT3-IN-2 is a FLT3 inhibitor with IC50 of ＜ 1 μM.
S5986	FLT3-IN-3	FLT3-IN-3 is a potent inhibitor of FLT3 with IC50 values of 13 nM and 8 nM for FLT3 WT and FLT3 D835Y, respectively. FLT3-IN-3 effectively suppresses the proliferation of FLT3-ITD-positive MV4-11 and MOLM-13 cell lines at low nanomolar concentrations.
S1837	Flubendazole	Flubendazole (Flumoxanal, NSC 313680) is an autophagy inducer by targeting Atg4B, used to treat internal parasite and worm infection.
S4850	Flucloxacillin sodium	Flucloxacillin sodium (Floxacillin sodium) is the sodium salt of flucloxacillin, a penicillin antibiotic used to treat bacterial infections.
S1331	Fluconazole	Fluconazole is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol,used in the treatment and prevention of superficial and systemic fungal infections.
S1666	Flucytosine (5-Fluorocytosine)	Flucytosine (5-Fluorocytosine) is an antifungal drug with IC50 of 0.93 μM in C. albicans.
S1491	Fludarabine	Fludarabine is a STAT1 activation inhibitor which causes a specific depletion of STAT1 protein (and mRNA) but not of other STATs. Also a DNA synthesis inhibitor in vascular smooth muscle cells. Fludarabine induces apoptosis.
S1229	Fludarabine Phosphate	Fludarabine Phosphate is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis.
E6062	Fludrocortisone	Fludrocortisone (Alflorone, 9α-Fludrocortisone) is a synthetic mineralocorticoid which increases pressor sensitivity to circulating catecholamines and angiotensin, alters intravascular volume, and has central adrenergic effects. It is beneficial in the treatment of hypotensive disorders: orthostatic hypotension, vasodepressor carotid sinus syndrome, and vasodepressor neurocardiogenic syndrome.
S3659	Fludrocortisone acetate	Fludrocortisone (9α-fluorocortisol) is a synthetic pregnane steroid and a halogenated derivative of cortisol. It is used to treat adrenogenital syndrome, postural hypotension, and adrenal insufficiency.
S4268	Flufenamic acid	Flufenamic Acid is an anti-inflammatory agent, and also acts as an ion channel modulator.
E0514	Flugestone 17-acetate	Flugestone 17-acetate (Flurogestone acetate) is a corticosteroid hormone.
S9973	Flumatinib (HH-GV-678)	Flumatinib (HH-GV-678) is a novel inhibitor of Bcr-Abl with IC50 values of 1.2 nM, 307.6 nM and 665.5 nM for c-Abl, PDGFRβand c-Kit, respectively.
S1332	Flumazenil	Flumazenil is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses.
S3181	Flumequine	Flumequine(R-802) is a synthetic chemotherapeutic antibiotic, inhibiting topoisomerase II with IC50 of 15 μM.
S4088	Flumethasone	Flumethasone (RS-2177, NSC-54702,Flumetasone) is a glucocorticoid receptor agonist, this complex binds to the nucleus causing a variety of genetic activation and repressions.
S2030	Flunarizine 2HCl	Flunarizine 2HCl (KW-3149, R14950) is a dihydrochloride salt form which is a calcium channel blocker with a K_i of 68 nM.
S2108	Flunixin Meglumin	Flunixin Meglumin(Banamine) is a potent inhibitor of the enzyme cyclooxygenase (COX) used as analgesic agent with anti-inflammatory and antipyretic activity.
S2470	Fluocinolone Acetonide	Fluocinolone Acetonide (Flucort-N) is a corticosteroid that binds to the cytosolic glucocorticoid receptor.
S2608	Fluocinonide	Fluocinonide (Vanos,nsc 101791) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema.
E7376	Fluorene	Fluorene, a polycyclic aromatic hydrocarbon (PAH), is a precursor to other fluorene compounds. Fluorene and its derivative can be used as a precursor to fluorene-based dyes.
S5488	Fluorescein	Fluorescein (Solvent Yellow 94, Resorcinolphthalein, Yellow fluorescein) is a manufactured organic compound and dye.
E7506	Fluorescein di(β-D-galactopyranoside)	Fluorescein di(β-D-galactopyranoside) is a fluorogenic substrate for β-galactosidase (λex=485 nm, λem=535 nm).
E7017	Fluorescein Diacetate	Fluorescein diacetate is a cell permeable esterase-substrate. Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1.
S6928	Fluorescein-5-isothiocyanate (FITC)	Fluorescein-5-isothiocyanate (FITC, Fluorescein isothiocyanate isomer I, 5-FITC) is a fluorescent probe capable of being conjugated to tissue and proteins.
E7087	Fluorescein-5-maleimide	Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm.
E4034	Fluorescent Brightener 28	Fluorescent Brightener 28 (Tinopal UNPA-GX) is a viability stain used for identification of structure chitin and fungi. It is also used as a fluorescent brightening agent for cellulose and polyamide fabrics, paper and in detergents and soaps.
E8230	fluorobenzene-d5	Fluorobenzene-d5 is the deuterated form of fluorobenzene.Fluorobenzene is used to prepare fluorine-containing antibacterial drugs (such as quinolones).
E1620	Fluorofurimazine	Fluorofurimazine is a novel furimazine analogue, with increased aqueous solubility enabling higher signal emission than furimazine for bioluminescence imaging. Fluorofurimazine enables higher substrate loading and improved optical imaging sensitivity in in-vivo.
S5486	Fluorometholone	Fluorometholone (Oxylone) is a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. It is usually used as eye drops in the treatment of allergic and inflammatory conditions of the eye.
S4228	Fluorometholone Acetate	Fluorometholone Acetate (NSC 47438,Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.
S5421	Fluoroquinolonic Acid	Fluoroquinolonic Acid (Ciprofloxacin Impurity A, Q-Acid) is an antibiotic and antimicrobial agent.
E4812	Fluoxetine	Fluoxetine (LY-110140 free base) is a selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine is used widely in the treatment of depression, anxiety-related symptoms and also displays anticonvulsant activity.
S1333	Fluoxetine HCl	Fluoxetine HCl is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, used in the treatment of depression.
S4569	Fluphenazine dihydrochloride	Fluphenazine dihydrochloride (Prolixin) is a phenothiazine-class D1DR and D2DR inhibitor. It also inhibits Histamine H1 Receptor.
S1334	Flupirtine maleate	Flupirtine maleate is the salt form of Flupirtine, which is a centrally acting non-opioid analgesia, is a selective neuronal potassium channel opener that also has NMDA receptor antagonist properties.
S6470	Fluralaner	Fluralaner (A1443, AH252723) is a systemic insecticide and acaricide that is administered orally.Fluralaner inhibits γ-aminobutyric acid (GABA)-gated chloride channels (GABAA receptors) and L-glutamate-gated chloride channels (GluCls)
S1679	Flurbiprofen	Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs).
S6457	Flurbiprofen Axetil	Flurbiprofen Axetil is one of the commonly used nonsteroidal anti-inflammatory drugs (NSAIDs) that nonselectively inhibits cyclooxygenase.
E1410	Fluspirilene	Fluspirilene(R 6218; Redeptin) is a non-competitive antagonist of L-type calcium channels with an IC50 of 0.03 μM in cell-free assays. Fluspirileneis a long-acting injectable depot antipsychotic agent used for schizophrenia.
S1908	Flutamide	Flutamide (SCH-13521) is an antiandrogen drug, with its active metablolite binding at androgen receptor with K_i values of 55 nM, and primarily used to treat prostate cancer.
S6487	fluticasone furoate	Fluticasone furoate (GW685698) is an inhaled corticosteroid/long-acting beta-agonist combination with a prolonged bronchodilator duration of action. It is used for the treatment of non-allergic and allergic rhinitis administered by a nasal spray.
S1992	Fluticasone propionate	Fluticasone Propionate (CCI-187881) is a synthetic glucocorticoid, used to treat non-allergic and allergic rhinitis.
E7391	Flutrimazole	Flutrimazole is an imidazole antifungal with dual anti-inflammatory and antifungal activity. Flutrimazole shows scarce transdermal penetration. Flutrimazole has the advantageous in the research of topical fungal infections with an inflammatory component.
E4981	Fluvastatin	Fluvastatin is a competitive inhibitor of HMG-CoA reductase with an IC50 value of 40 and 100 nM in human liver microsomes. Fluvastatin also exerts cytoprotective effects against oxidative stress through the Nrf2-dependent antioxidant pathway.
S1909	Fluvastatin Sodium	Fluvastatin Sodium inhibits HMG-CoA reductase activity with IC50 of 8 nM in a cell-free assay.
S1336	Fluvoxamine (DU-23000) maleate	Fluvoxamine maleate (DU-23000, MK-264) is a selective serotonin (5-HT) reuptake inhibitor (SSRI), used in the treatment of obsessive-compulsive disorder.
E7658	Fluxametamide	Fluxametamide is an insecticide with wide spectrum, acts as an antagonist of GABA- and glutamate-gated chloride channels, with IC50 of 1.95 nM and 225 nM for M. domestica GABACls and GluCls.
S9712	Fluzoparib (SHR-3162)	Fluzoparib (SHR3162, HS10160) is a potent Poly (ADP-ribose) polymerase (PARP) inhibitor that shows anti-tumor activity, with an IC50 of 1.46±0.72 nM for PARP1.
S8541	FM-381	FM-381 is a JAK3 specific reversible covalent inhibitor with IC50 of 127 pM for JAK3 and demonstrates 400-, 2,700- and 3,600-fold selectivity over JAK1, JAK2, and TYK2, respectively.
E7594	FM1-43	FM1-43 is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM1-43 is widely used in endocytic and exospic membrane structure markers.
E1712	FM19G11	FM19G11 is a hypoxia-inducible factor-1-alpha (HIF-1α) inhibitor, and it inhibits hypoxia-induced luciferase activity with an IC50 of 80 nM in HeLa cells.
E1892	FM4-64	FM4-64 is a highly lipophilic yet water-soluble styryl dye that specifically binds to cellular membranes and intracellular organelles, generating fluorescence. This compound serves as a valuable marker for studying endocytic and exocytic membrane structures.
E7754	FMK 9a	FMK 9a is an autophagin-1 inhibitor with IC50 values of 80 and 73 μM in FRET and LRA assay.
F3200	FMO3 Antibody [B22C1]
E8239	Fmoc-L-Val-OH-d8	Fmoc-L-Val-OH-d8 is the deuterated derivative of Fmoc-D-Val-OH. Fmoc-D-Val-OH is a valine derivative.
E8240	Fmoc-Leu-d10	Fmoc-Leu-d10 is the deuterated form of Fmoc-Leu-OH. Fmoc-Leu-OH is an intermediate used to protect leucine in solid phase peptide synthesis. The peptide drugs synthesized by Fmoc-Leu-OH may have activities such as regulating insulin sensitivity.
S0091	Fmoc-Val-Ala-PAB	Fmoc-Val-Ala-PAB (Fmoc-Val-Ala-PAB-OH) is a useful and cleavalbe linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery.
S6688	Fmoc-Val-Cit-PAB	Fmoc-Val-Cit-PAB (Fmoc-Val-Cit-PAB-OH) is a cleavable linker for antibody-drug conjugates (ADC).
E8241	Fmoc-α-d2-glycine	Fmoc-α-d2-glycine is the deuterated derivative of Fmoc-Gly-OH. Fmoc-Gly-OH is a glycine derivative protected by an Fmoc group and can be used in compound synthesis.
F1373	FMRP Antibody [D18E17]	FMRP,Fragile X Mental Retardation Protein
E2658	FN-1501	FN-1501 is a potent inhibitor of Fms-like receptor tyrosine kinase 3 (FLT3) and cyclin-dependent kinase (CDK), with IC50s of 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively.
F1645	FNDC5 Antibody [H22N1]
F3977	FNIP1 Antibody [B16M7]
A5331	FNTB Rabbit Recombinant mAb	FNTB Rabbit Recombinant mAb detects endogenous level of total FNTB.
E3768	Foeniculum Vulgare Extract	Foeniculum Vulgare Extract is obtained from Foeniculum vulgare (Apiaceae), which is traditionally suggested for the fertility improvement in Iranian lore due to its antioxidant and phytoestrogen compounds.
F2457	Folate Binding Protein / FBP Antibody [E8P21]
S4605	Folic acid	Folic acid (Folacin, Vitamin B9, Vitamin M, Pteroylglutamic acid, Folate), a B vitamin, plays an important role in cell division and in the synthesis of amino acids and nucleic acids like DNA.
S5790	Folinic acid (Leucovorin)	Folinic acid (Leucovorin) is a biological folic acid that increases the level of reduced folates in tissues, which promotes the inhibition of thymidylate synthase (TS).Solutions are unstable and should be fresh-prepared.
E8122	Folitixorin	Folitixorin (5,10-methylenetetrahydrofolate) is a cofactor and an analog of leucovorin. Folitixorin is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research.
S1717	Fomepizole	Fomepizole (4-methylpyrazole, Antizol, Antizol-Vet) is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
S3736	Fondaparinux Sodium (Org 31540)	Fondaparinux Sodium (Org 31540, Natural heparin pentasaccharide, Fondaparin, SR-90107A) is a synthetic glucopyranoside with antithrombotic activity. It selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin; a synthetic inhibitor of Factor Xa.
S6159	Food Yellow 3	Food Yellow 3 (Sunset yellow) is an azo dye that is useful in fermented foods which must be heat treated.
S5306	Forchlorfenuron (CPPU)	Forchlorfenuron (CPPU) is a synthetic cytokinin that inhibits septins and exhibits anti-parasitic, anticancer, and anti-angiogenic activities.
S1111	Foretinib	Foretinib is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met (c-Met) and KDR with IC50 of 0.4 nM and 0.9 nM in cell-free assays. Less potent against Ron, Flt-1/3/4, Kit (c-Kit), PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR. Phase 2.
E2922	Formamide	Formamide (Methanamide; Formimidic acid) is a clear liquid amide derived from formic acid. It allows for the denaturation and renaturation of nucleic acids at room temperature. Formamide-induced DNA denaturation when combined with detection of denatured DNA with a monoclonal antibody (MAb) makes it possible to specifically identify the apoptotic cells.
E2995	Formamide deionized	Formamide deionized(Methanamide, Formimidic acid) is a clear liquid amide derived from formic acid that serves as an essential solvent for catalytic hydrogenation reactions and acts as a reagent in the creation of diverse organometallic compounds.
S2208	Formestane	Formestane (CGP-32349, NSC 282175) is a second generation selective aromatase inhibitor with an IC50 of 80 nM.
S2299	Formononetin	Formononetin (Formononetol, Biochanin B) is a phytoestrogen from the root of Astragalus membranaceus and an O-methylated isoflavone.
E4892	Formoterol	Formoterol is a highly selective and potent long-acting beta2-adrenergic agonist that functions by binding to and activating beta2-adrenergic receptors on the smooth muscle cells of the airways. It is used in the treatment of patients with chronic obstructive pulmonary disease (COPD).
S2020	Formoterol Hemifumarate	Formoterol Hemifumarate (Eformoterol, CGP 25827A, NSC 299587, YM 08316,Formoterol fumarate) is a potent, selective and long-acting β2-adrenoceptor agonist used in the management of asthma and chronic obstructive pulmonary disease(COPD).
E8203	Forodesine	Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels.
S2449	Forskolin (Colforsin)	Forskolin (Colforsin) is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types, commonly used to raise levels of cAMP in the study and research of cell physiology. Forskolin also activates PXR and FXR activity. Forskolin stimulates autophagy.
E3415	Forsythia suspensa Extract	Forsythia suspensa Extract is extracted from Forsythia suspensa.
S3926	Forsythin	Forsythin (FOR, Phillyrin) is an active ingredient extracted from the fruit of the medicinal plant Forsythia suspensa (Thunb.) Vahl and has been shown to have antioxidant, antibacterial and antiinflammatory properties.
S9184	Forsythoside B	Forsythoside B is a phenylethanoid glycoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant. Forsythoside B has potent neuroprotective effects and has anti-inflammation, antioxidant, and antisepsis properties. Forsythoside B could inhibit TNF-alpha, IL-6, IκB and modulate NF-κB.
F3379	Fos B Antibody [G14F16]	Fos B,FosB
E6028	Fosamprenavir	Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester proagent of the antiretroviral protease inhibitor Amprenavir, with improved solubility. Anti-HIV infection.
S6581	Fosamprenavir calcium salt	Fosamprenavir(GW433908G) is a pro-drug of the protease inhibitor and antiretroviral drug amprenavir. It is used for the treatment of HIV-1 infections.
S3038	Fosaprepitant dimeglumine salt	Fosaprepitant dimeglumine salt (MK-0517) is a water-soluble phosphoryl prodrug for Aprepitant which is a NK1 antagonist.
S7204	Fosbretabulin (Combretastatin A4 Phosphate) Disodium	Fosbretabulin (Combretastatin A4 Phosphate) Disodium is the water-soluble prodrug of Combretastatin A4 (CA4), which is a microtubule-targeting agent that binds β-tubulin with K_d of 0.4 μM in a cell-free assay. Fosbretabulin Disodium inhibits the polymerization of tubulin with IC50 of 2.4 μM, and also disrupts tumor vasculature. Fosbretabulin disodium induces mitotic arrest and apoptosis in endothelial cells. Phase 3.
S3076	Foscarnet Sodium	Foscarnet Sodium (Phosphonoformate) inhibits viral RNA polymerases, reverse transcriptase, and DNA polymerases through noncompetitive inhibition with dNTPs.
S8968	Foscenvivint (PRI-724)	Foscenvivint (PRI-724) is a potent and specific inhibitor that disrupts the interaction of β-catenin and CBP.
E0465	Fosciclopirox	Fosciclopirox(CPX-POM) selectively delivers the active metabolite, Ciclopirox (CPX) that targets γ-secretase complex (Presenilin 1 and Nicastrin)2. It is used in the treatment of urothelial cancer and a number of solid and hematologic malignancies.
S6467	Fosfluconazole	Fosfluconazole is a water-soluble phosphate prodrug of fluconazole, which is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
S3710	Fosfomycin calcium	Fosfomycin (phosphomycin, phosphonomycin) is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.
S5048	Fosfomycin Disodium	Fosfomycin (Phosphonemycin) is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an early stage in cell wall synthesis.
S5729	Fosfosal	Fosfosal (2-phosphonoxy benzoic acid) is a non-acetylated salicylic acid derivative, with analgesic and anti-inflammatory activity, but without effects on PG biosynthesis in vitro.
S2095	Fosinopril Sodium	Fosinopril Sodium (SQ28555) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.
E7956	Fosmidomycin sodium salt	Fosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial agent, which is active against both Gram-negative and Gram-positive bacteria.
S6482	Fosphenytoin (disodium)	Fosphenytoin (disodium) is the sodium salt form of fosphenytoin, a prodrug that is hydrolyzed to the anticonvulsant phenytoin upon parental administration.
S2625	Fostamatinib (R788)	Fostamatinib (R788), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.
S2206	Fostamatinib (R788) disodium	Fostamatinib disodium (R788, Tamatinib Fosdium), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.
S4944	Fostamatinib disodium hexahydrate	Fostamatinib (R788) disodium (Tamatinib Fosdium) hexahydrate, a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM in a cell-free assay.
S7220	Fostemsavir	Fostemsavir (BMS-663068, Rukobia), the phosphonooxymethyl prodrug of BMS626529, is an attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells with EC50 of < 10 nM.
E4891	Fostemsavir Tris	Fostemsavir Tris(BMS-663068 Tris) is a phosphonooxymethyl prodrug of BMS-626529, formulated as a tris(hydroxymethyl)aminomethane salt. It inhibits human immunodeficiency virus type 1 (HIV-1) by binding to the gp120 protein, preventing the virus from attaching to CD4+ T-cells.
E4752	FOT1（CN128）hydrochloride	FOT1 (CN128, CN328) hydrochloride is a potent and orally active hydroxypyridinone iron chelator with potential for treating systemic iron overload and β-thalassemia. It also helps prevent the onset and slows early-stage Parkinson’s disease symptoms by reducing oxidants and toxic intermediates from iron-mediated dopamine oxidation.
F2921	Fox2 / RBM9 Antibody [M18D7]	Fox2 / RBM9,RBM9
F2156	FOXA1 Antibody [E4N8]	FOXA1,FoxA1/HNF3α
F3403	FOXA2 Antibody [H18B12]	FOXA2,FoxA2/HNF3β
F1084	FOXC1 Antibody [B1N18]
F1331	FoxC2 Antibody [C7N1]
F1332	FoxD3 Antibody [N18E17]
F3932	FOXJ1 Antibody [P11C9]
F0378	FoxM1 Antibody [K19K15]
F0141	FoxO1 Antibody [J3J15]	FKHR/FOXO1,FoxO1,FOXO1A
A5001	FOXO1A Rabbit Recombinant mAb	FOXO1A Rabbit Recombinant mAb detects endogenous levels of total FOXO1a.
F4129	FoxO3a Antibody [L2E7]
F1037	FOXO4/AFX Antibody [K6L17]	FoxO4,FOXO4/AFX
F0887	FoxP1 Antibody [J18J7]
A5142	FOXP1 Rabbit Recombinant mAb	FOXP1 Rabbit Recombinant mAb detects endogenous level of FOXP1.
F2642	FoxP2 Antibody [E2F20]
F0054	FOXP3 Antibody [L7A5]
S6961	Foxy-5	Foxy-5, a Wnt-5a mimicking hexapeptide, is a WNT signalling pathway modulator potentially for the treatment of metastatic breast cancer, prostate cancer and colorectal cancer.
S3511	FOY251	FOY251, an active metabolite of camostat mesilate, is an inhibitor of synthetic serine protease. FOY251 inhibits SARS-CoV-2 infection.
S7451	FPH1	FPH1 is a small molecule, which promotes expansion of iPS-derived hepatocytes.
S7452	FPH2 (BRD-9424)	FPH2 (BRD-9424) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.
S0759	FPL 62064	FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and prostaglandin synthetase (cyclooxygenase, COX) with IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and seminal vesicle prostaglandin synthetase, respectively. FPL 62064 has potent anti-inflammatory activity.
E7571	FPR Agonist 43	FPR Agonist 43 (compound 43) is a dual formyl peptide receptor 1 (FPR1) and formyl peptide receptor 2 (FPR2)/ALX agonist.
S8185	FPS-ZM1	FPS-ZM1 is a blood-brain-barrier permeant, non-toxic, tertiary amide compound which is a high affinity RAGE-specific inhibitor, blocking Aβ binding to the V domain of RAGE.
E1275	FR054	FR054 is a novel inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3 with a remarkable anti-breast cancer effect.
F0731	FRA1 Antibody [H14K9]
F1284	Fra2 Antibody [K7K7]
F2434	Fragilis Antibody [B5B19]	Fragilis,IFITM3
L1600	Fragment Library	A unique collection of 1015 Fragment compounds for Fragment-Based Drug Discovery (FBDD).
E0511	Framycetin sulphate	Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM, and competes for specific divalent metal ion binding sites in RNase P RNA, also inhibits hammerhead ribozyme with a Ki of 13.5 μM.
S9503	Fraxetin	Fraxetin (7,8-dihydroxy-6-methoxy coumarin), found in Fraxinus rhynchophylla, shows potent antioxidant activity.fraxetin alleviates lipid peroxidation, enhances hepatic antioxidant capabilities, inhibits CYP2E1 activity, and reduced the inflammatory mediators, including TNF-α and IL-1β via up-regulation of hemeoxygenase-1 (HO-1) protein.
S9296	Fraxin	Fraxin (Fraxetin-8-O-glucoside), a main active component isolated from Cortex Fraxini, possesses a variety of bioactivities such as anti-inflammatory, antioxidant, analgesic, antimicrobial, antiviral, immunomodulatory, anti-hyperuricemia and diuresis.
S2418	Frentizole	Frentizole (Frentizol) is a novel inhibitor of amyloid beta peptide (Abeta) binding alcohol dehydrogenase (ABAD) interaction with IC50 of 200 μM. Frentizole is a nontoxic antiviral and immunosuppressive agent used clinically in rheumatoid arthritis and systemic lupus erythematosus.
E3578	Fringed pink Extract	Fringed Pink Extract is extracted from Dianthus superbus, which has anti-inflammatory activity.
E3099	Fritillaria Cirrhosa Seed Extract	Fritillaria Cirrhosa Seed Extract is extracted from the seeds of Fritillaria Cirrhosa, which is famous for its antitussive, expectorant, anti-asthma and anti-inflammatory properties, and is widely used to treat respiratory diseases.
E3098	Fritillariae Cirrhosae Bulbus Extract	Fritillariae Cirrhosae Bulbus Extract is obtained from Fritillariae cirrhosae, mediates apoptosis through a STAT1 and STAT4-mediated co-regulatory network, which may be the key novel mechanism for its antitumor activity.
E3867	Fritillariae Thunbergii Bulbus Extract	Fritillariae Thunbergii Bulbus Extract is extracted from Fritillariae thunbergii bulbus, which is used to treat symptoms of cough and airway congestion in the chest due to pathological colds and damp phlegm.
A5847	Frizzled 8 Rabbit Recombinant mAb	Frizzled 8 Rabbit Recombinant mAb detects endogenous levels of total Frizzled 8
S5848	Frovatriptan Succinate	Frovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.
E6067	Frovatriptan succinate hydrate	Frovatriptan succinate hydrate ((R)-Frovatriptan succinate hydrate, SB 209509 succinate) is a potent, selective and orally active agonist of 5-HT1B with pEC50 value of 8.2 and 5-HT1D receptor. It displays >10-fold selectivity for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1F, and 5-HT7 and a >1000-fold selectivity over other 5-HT, dopamine, histamine H1, and α1-adrenoceptor.
E7386	Fructose	Fructose (beta-D-Fructopyranose) is a highly soluble, sweet monosaccharide used as a sweetener in food and beverages, providing moisture retention and enhancing flavor. It functions as a humectant, lowers freezing points, and improves texture in various products.
E3847	Fructus Akebiae Extract	Fructus Akebiae Extract is extracted from Fructus akebiae, which is used for the treatment of mental disorders.
E3006	Fructus Anisi Stellati Extract	Fructus Anisi Stellati Extract is extracted from the fruit of Illicium verum, which involves in signalling pathways that target cancer cell apoptosis, proliferation, and tumour metastasis in Gastric cancer cells.
E3474	Fructus Chebulae Extract	Fructus Chebulae Extract is extracted from the mature fruit of Terminalia chebula Retz., which can rescue neuronal cell death against ischemia-related damage.
E3721	Fructus mume Extract	Fructus mume Extract is obtained from the processed fruit of Fructus mume Sieb. et Zucc., which effectively improves cognitive impairment in familial Alzheimer's disease, scopolamine-induced memory impairment, and chronic cerebral hypoperfusion-induced cognitive impairment.
E3393	Fructus azedarach Extract	Fructus azedarach Extract is extracted from Fructus azedarach.
S5667	Fruquintinib	Fruquintinib is a small molecule inhibitor with strong potency and high selectivity against VEGFR family. It inhibits VEGFR 1, 2, 3, with IC50 values of 33 nM, 35 nM and 0.5 nM, respectively and shows only weak inhibition of RET, FGFR-1 and c-kit kinases.
E1574	FSEN1	FSEN1 is a potent and non-competitive FSP1 inhibitor with an IC50 value of 313 nM. It triggers iron death in cancer cells by inhibiting FSP1 and can be used in research of cancer.
E0309	FSG67	FSG67 is an inhibitor of glycerol 3-phosphate acyltransferase (GPAT) with an IC50 of 24 μM. It increases oxidative metabolism in mature adipocytes and blunts liver regeneration after acetaminophen overdose by altering GSK3β and Wnt/β-catenin signaling.
S8428	FSL-1	FSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection.
E7157	FSLLRY-NH2	FSLLRY-NH2 is a protease-activated receptor 2 (PAR2) inhibitor.
S9915	FSLLRY-NH2 TFA	FSLLRY-NH2 TFA (FSY-NH2) is a selective protease-activated receptor 2 (PAR2) inhibitor with an ic50 of 50 µM in PAR2-KNRK cells.
E7749	FT011	FT011 is an anti-fibrotic agent, reduces mRNA expression of collagens I and III and inhibits collagen synthesis. FT011 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
S6666	FT113	FT113 is a potent inhibitor of fatty acid synthase (FAS/FASN) with ic50 of 213 nM.
S6464	Ftaxilide	Ftaxilide is a novel antituberculosis agent.
S7465	FTI 277 HCl	FTI 277 HCl is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia.
F2236	FTO Antibody [K15C9]	Fatso,FTO,FTO Antibody
E7916	FTY720 (S)-Phosphate	FTY720 (S)-Phosphate is an agonist of S1P receptor 1 (S1PR1), used in the research of acute inflammatory diseases such as acute lung injury.
F2762	FUBP1 Antibody [E17K24]
A5347	FUBP1 Rabbit Recombinant mAb	FUBP1 Rabbit Recombinant mAb detects endogenous level of total FUBP1.
E0365	Fucoidan	Fucoidan is an anionic sulfated polysaccharide extracted from marine brown algae with a large range of biological activities, including anti-inflammatory, anti-cancer, anti-viral, anti-oxidation, anticoagulant, antithrombotic, anti-angiogenic and anti-Helicobacter pylori, etc.
E3488	Fucus vesiculosis Extract	Fucus Vesiculosis Extract is extrcated from Fucus vesiculosus, which has antifungal properties.
S2129	Fudosteine	Fudosteine is a cysteine derivative and a MUC5AC mucin hypersecretion inhibitor, used as a muco-active agent with indications for chronic respiratory diseases.
S0042	Fulacimstat	Fulacimstat (BAY1142524) is an orally available inhibitor of chymase with IC50 of 4 nM and 3 nM for human and hamster chymase enzyme, respectively.
S1191	Fulvestrant (ICI-182780)	Fulvestrant is an estrogen receptor (ER) antagonist with IC50 of 0.94 nM in a cell-free assay. Fulvestrant also induces autophagy and apoptosis and has antitumor activity.
E1843	Fulzerasib	Fulzerasib (IBI351, GFH925) is an irreversible small molecule inhibitor for KRAS G12C mutation blocking KRAS pathway signaling pERK with an IC50 of 37 nM. It demonstrates potent anti-tumor activity in multiple KRAS G12C-mutant tumor models including human pancreatic cancer, human lung adenocarcinoma, colorectal adenocarcinoma, and lung cancer models.
S7784	Fumagillin	Fumagillin(Amebacilin,NSC9168) is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.
F0888	Fumarase Antibody [E1P13]
E1403	Fumarate hydratase-IN-1	Fumarate hydratase-IN-1 is a small molecule cell-permeable inhibitor of fumarate hydratase. It induce alteration of TCA cycle metabolites, modulation of cytosolic processes, and substantial redox stress responses.
S4952	Fumaric acid	Fumaric acid (Fumarate, 2-Butenedioic acid, Trans-Butenedioic acid) is an intermediate in the citric acid cycle used by cells to produce energy in the form of adenosine triphosphate (ATP) from food; also a product of the urea cycle.
E7980	Fumitremorgin C	Fumitremorgin C is a potent and selective ABCG2/BRCP inhibitor.
S7866	Fumonisin B1	Fumonisin B1 (Macrofusine) is a mycotoxin produced by Fusarium moniliforme Sheldon and a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase), an enzyme vital for the de novo synthesis of sphingolipids. It exhibits an IC50 of 0.1 µM for N-acyltransferase (ceramide synthase) in rat liver microsomes and also reduces the conversion of [3H]sphingosine to [3H]ceramide in intact hepatocytes.
E7400	Furafylline	Furafylline is a potent and selective inhibitor of human cytochrome P450IA2 with an IC50 of 0.07 μM.
S3709	Furagin	Furagin (NF-416, F-35, Akritoin, Furazidin, Furazidine) is 2-substituted 5-nitrofuran, chemically and structurally similar to well-known antibacterial compound nitrofurantoin with antimicrobial activities.
S4203	Furaltadone HCl	Furaltadone HCl(Altafur hydrochloride) is an antibacterial and has distinct curative effect in the treatment of coccidiosis.
E7603	Furamidine dihydrochloride	Furamidine dihydrochloride (DB75 dihydrochloride, NSC 305831 dihydrochloride) is a potent and selective inhibitor of protein arginine methyltransferase 1 (PRMT1) with an IC50 of 9.4 μM. It is also a potent inhibitor of tyrosyl-DNA phosphodiesterase (Tdp1). It exhibits potent anti-Plasmodium vivax and antiparasitic activity in vitro and in vivo, and its ability to disrupt mitochondrial membranes also supports its use as an antimicrobial agent.
S4528	Furazolidone	Furazolidone(Furoxone) is a synthetic nitrofuran derivative with bactericidal or bacteriostatic activity when used against Gram-positive and Gram-negative bacteria.Furazolidone can be used to induce animal models of Cardiomyopathy.
S5831	Furfuryl acetate	Furfuryl acetate (Furan-2-ylmethyl, 2-Furanmethanol, 2-Acetoxymethylfuran) is widely used as a flavoring agent in food and bakery.
E5806	Furimazine	Furimazine (PBI 3939) is a synthetic imidazopyrazinone compound that serves as a substrate for the NanoLuc luciferase (Nluc) enzyme. When combined with Nluc, Furimazine produces exceptionally bright bioluminescent signals in mammalian cells, significantly enhancing the sensitivity of bioluminescence imaging (BLI) applications.
S1603	Furosemide	Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used in the treatment of congestive heart failure and edema.
S5194	Furosemide sodium	Furosemide (Frusemide) sodium is a potent and orally active inhibitor of Na-K-Cl cotransporter (NKCC). Furosemide sodium is a subtype-selective antagonist of gamma-aminobutyric acid type A (GABAA) receptor.
S6614	Fursultiamine	Fursultiamine (Thiamine tetrahydrofurfuryl disulfide) is a nutritional supplement and vitamin B1 derivative, with potential antineoplastic activity.
A5383	FUS/TLS Rabbit Recombinant mAb	FUS/TLS Rabbit Recombinant mAb detects endogenous level of total FUS/TLS.
E8103	Fuscoside	Fuscoside (OPC-21268) is an orally effective, nonpeptide, vasopressin V1 receptor antagonist with an IC50 of 0.4 μM.
S4663	Fusidate Sodium	Fusidate Sodium (Fucidin, SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections.
S3971	Fusidine	Fusidine (Fusidic Acid), isolated from Fusidium coccineum, is a steroidal antibiotic that inhibits protein synthesis.
S8848	Futibatinib (TAS-120)	Futibatinib (TAS-120) is an irreversible fibroblast growth factor receptor (FGFR) inhibitor which inhibits all 4 subtypes of FGFR with enzyme IC50 values of 1.8 nM, 1.4 nM, 1.6 nM and 3.7 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.
E1831	FX-909	FX-909 is an orally available inverse agonist and inhibitor of the transcription factor (TF) peroxisome proliferator activated receptor gamma (PPARG, PPARγ) ), which exhibits anti-tumor activity in vivo.
S8591	FX1	FX1 is a selective BCL6 BTB inhibitor with an IC50 value of 35 μM in reporter assays. FX1 shows great selectivity against a panel of 50 different kinases. 10 μM FX1 fails to significantly inhibit of any of these kinases. FX1 induces apoptosis.
S8928	FX11	FX-11(LDHA Inhibitor FX11) is a potent inhibitor of lactate dehydrogenase A (LDHA)) with IC50 of 49.27 μM in BxPc-3 cells.
F1191	FXR1 Antibody [G10D7]
F1423	FXR2 Antibody [M16M21]
F2554	Fyn Antibody [K9B3]